3P1YA

Crystal structure of the chimeric archaeoglobus fulgidus rna splicing endonuclease with the broadest substrate specificity
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
314
structure length
314
Chain Sequence
IGGDFAVVKAKKSLERRGFGVKRGDKIYLHPLEVVYLQIKGIESFGELEDVLSWAESRMEDFSTYYFVYEDLRDRGNKVKIQGEFLLTKKPYLPISERKTIRMEEIAEKARNFDELRLAVVDEESEITYFRVYEPDMMGEQKEELPEIAGILSDEYVITKQTEIFSRYFYGSPLDVEKPRGADFEGPVTLSLIESLYLLDLGKLNLLNADREELVKRAREVERNFDRRYEVYRNLKERGFVVKTGFKFGSEFRVYRKVESVDDLPHSEYLVDIADSREIRLIDLARAVRLAQNVRKRMVFAYGKNYLCFERVKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix, a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop
pubmed doi rcsb
molecule tags Hydrolase
source organism Archaeoglobus fulgidus
molecule keywords tRNA-splicing endonuclease
total genus 99
structure length 314
sequence length 314
chains with identical sequence B, C, D
ec nomenclature ec 4.6.1.16: tRNA-intron lyase.
pdb deposition date 2010-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
A PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
A PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
A PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 3p1yA02
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3p1yA03
3.40.1350.150 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3p1yA01
1A79A 5FDKA 1OB8A 4TKDA 1RLVA 3P1ZB 1R11A 1F1ZA 3IEYB 3DNXA 2WCWA 1R0VA 1GEFA 1IPIA 1RZNA 1HH1A 4QBOA 2CV8A 4TKKA 2ZYZA 2WJ0A 3AJVA 2FCOA 1ZP7A 2VLDA 2OKFA 4QBNA 2GJWA 4FZ2A 2WIWA 1T0FA 2WIZA 2INBA 3P1ZA 2ZYZB 3IEYA 2WCZA 2OSTA 1Y1OA 1Y88A 2GW6A 4QBLA 3AJVB 3FOVA 3P1YA 1XMXA 1OB9A 2EO0A 3IF0X
chains in the Genus database with same CATH superfamily
1A79A 1OB8A 4TKDA 3THXA 1OH6A 1UWVA 1HH1A 1YNMA 2WTUA 4QBOA 4G6VA 2FCOA 2OKFA 2FKHB 2GJWA 2BH2A 4FZ2A 1T0FA 2INBA 2ZYZB 3FOVA 2O8EB 2DBSA 2FKCA 1OB9A 2O8BB 2O8FB 3BT7A 4G6UA 3P1ZB 1F1ZA 3IEYB 3THYB 1R0VA 4DAVA 1IPIA 4TKKA 2ZYZA 2VLDA 2O8EA 2O8BA 3THWB 2FL3A 1NG9A 2O8FA 2JJQA 2WIWA 2WIZA 3P1ZA 2OSTA 3IEYA 1FW6A 1Y1OA 4QBLA 3THYA 1XMXA 1W7AA 2EO0A 5FDKA 1RLVA 2FZ4A 1R11A 4DA2A 3DNXA 2VS1A 3THWA 1RZNA 2O8DB 4LQEA 2W8MA 2WJ0A 2FWRA 1ZP7A 4QBNA 2CZRA 4DAPA 4ZQUA 2O8CB 3ZLJA 2WCZA 2GW6A 3AJVB 3IF0X 2O8DA 1WBDA 1EWQA 2IXSA 2Z0RA 2FLCA 2WCWA 1GEFA 4EV1A 1WBBA 2CV8A 2O8CA 1NNEA 3THXB 1OH7A 3AJVA 3K0SA 1Y88A 1E3MA 1OH5A 3P1YA 4E6ZA 1WB9A 1OH8A
chains in the Genus database with same CATH topology
1A79A 5FDKA 1OB8A 4TKDA 3BT7A 4G6UA 1RLVA 3P1ZB 1R11A 1F1ZA 2IXSA 3IEYB 2Z0RA 1UWVA 4DA2A 3DNXA 2FLCA 2VS1A 2WCWA 1R0VA 4DAVA 1GEFA 1IPIA 1RZNA 4EV1A 1HH1A 1YNMA 4QBOA 2CV8A 4LQEA 2W8MA 2ZYZA 4TKKA 2WJ0A 4G6VA 3AJVA 2FCOA 1ZP7A 2VLDA 2OKFA 4QBNA 2FKHB 2GJWA 2FL3A 4FZ2A 2CZRA 2JJQA 2BH2A 2WIWA 4DAPA 1T0FA 4ZQUA 2WIZA 2INBA 3P1ZA 2ZYZB 3IEYA 2WCZA 2OSTA 1Y1OA 1Y88A 2GW6A 4QBLA 3AJVB 3FOVA 3P1YA 2DBSA 1XMXA 4E6ZA 2FKCA 1OB9A 2EO0A 3IF0X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A79 A;  5FDK A;  1OB8 A;  4TKD A;  1RLV A;  3P1Z B;  1R11 A;  1F1Z A;  3IEY B;  3DNX A;  2WCW A;  1R0V A;  1GEF A;  1IPI A;  1RZN A;  1HH1 A;  4QBO A;  2CV8 A;  4TKK A;  2ZYZ A;  2WJ0 A;  3AJV A;  2FCO A;  1ZP7 A;  2VLD A;  2OKF A;  4QBN A;  2GJW A;  4FZ2 A;  2WIW A;  1T0F A;  2WIZ A;  2INB A;  3P1Z A;  2ZYZ B;  3IEY A;  2WCZ A;  2OST A;  1Y1O A;  1Y88 A;  2GW6 A;  4QBL A;  3AJV B;  3FOV A;  3P1Y A;  1XMX A;  1OB9 A;  2EO0 A;  3IF0 X; 
#chains in the Genus database with same CATH topology
 1A79 A;  1OB8 A;  4TKD A;  3THX A;  1OH6 A;  1UWV A;  1HH1 A;  1YNM A;  2WTU A;  4QBO A;  4G6V A;  2FCO A;  2OKF A;  2FKH B;  2GJW A;  2BH2 A;  4FZ2 A;  1T0F A;  2INB A;  2ZYZ B;  3FOV A;  2O8E B;  2DBS A;  2FKC A;  1OB9 A;  2O8B B;  2O8F B;  3BT7 A;  4G6U A;  3P1Z B;  1F1Z A;  3IEY B;  3THY B;  1R0V A;  4DAV A;  1IPI A;  4TKK A;  2ZYZ A;  2VLD A;  2O8E A;  2O8B A;  3THW B;  2FL3 A;  1NG9 A;  2O8F A;  2JJQ A;  2WIW A;  2WIZ A;  3P1Z A;  2OST A;  3IEY A;  1FW6 A;  1Y1O A;  4QBL A;  3THY A;  1XMX A;  1W7A A;  2EO0 A;  5FDK A;  1RLV A;  2FZ4 A;  1R11 A;  4DA2 A;  3DNX A;  2VS1 A;  3THW A;  1RZN A;  2O8D B;  4LQE A;  2W8M A;  2WJ0 A;  2FWR A;  1ZP7 A;  4QBN A;  2CZR A;  4DAP A;  4ZQU A;  2O8C B;  3ZLJ A;  2WCZ A;  2GW6 A;  3AJV B;  3IF0 X;  2O8D A;  1WBD A;  1EWQ A;  2IXS A;  2Z0R A;  2FLC A;  2WCW A;  1GEF A;  4EV1 A;  1WBB A;  2CV8 A;  2O8C A;  1NNE A;  3THX B;  1OH7 A;  3AJV A;  3K0S A;  1Y88 A;  1E3M A;  1OH5 A;  3P1Y A;  4E6Z A;  1WB9 A;  1OH8 A; 
#chains in the Genus database with same CATH homology
 1A79 A;  5FDK A;  1OB8 A;  4TKD A;  3BT7 A;  4G6U A;  1RLV A;  3P1Z B;  1R11 A;  1F1Z A;  2IXS A;  3IEY B;  2Z0R A;  1UWV A;  4DA2 A;  3DNX A;  2FLC A;  2VS1 A;  2WCW A;  1R0V A;  4DAV A;  1GEF A;  1IPI A;  1RZN A;  4EV1 A;  1HH1 A;  1YNM A;  4QBO A;  2CV8 A;  4LQE A;  2W8M A;  2ZYZ A;  4TKK A;  2WJ0 A;  4G6V A;  3AJV A;  2FCO A;  1ZP7 A;  2VLD A;  2OKF A;  4QBN A;  2FKH B;  2GJW A;  2FL3 A;  4FZ2 A;  2CZR A;  2JJQ A;  2BH2 A;  2WIW A;  4DAP A;  1T0F A;  4ZQU A;  2WIZ A;  2INB A;  3P1Z A;  2ZYZ B;  3IEY A;  2WCZ A;  2OST A;  1Y1O A;  1Y88 A;  2GW6 A;  4QBL A;  3AJV B;  3FOV A;  3P1Y A;  2DBS A;  1XMX A;  4E6Z A;  2FKC A;  1OB9 A;  2EO0 A;  3IF0 X; 
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