3P1ZB

Crystal structure of the aperopyrum pernix rna splicing endonuclease
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
180
structure length
180
Chain Sequence
PIKASGVLIGDSVLVTDVEQARSLYSCGYYGQPLDVEKPRGADFEGPLRLSLIESLYLAEKGVLEVAKPDGSSVGVEDLRTAVRGNPRFSMLYNIYRDLRERGFVVRSGLKFGSDFAVYRLGPGIDHAPFIVHAYSPEDNIDPVEIVRAGRLSHSVRKKFVFAVTRGGDVSYLMIDWFRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix, a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop
pubmed doi rcsb
molecule tags Hydrolase
source organism Aeropyrum pernix
molecule keywords Putative uncharacterized protein
total genus 46
structure length 180
sequence length 180
chains with identical sequence D, F, H, J, L
ec nomenclature ec 4.6.1.16: tRNA-intron lyase.
pdb deposition date 2010-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
B PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 3p1zB01
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3p1zB02
3AJVB 1A79A 3IEYA 1OB8A 4TKDA 2GW6A 4QBNA 1XMXA 3AJVA 2WIZA 2GJWA 2OKFA 2EO0A 4FZ2A 1Y1OA 5FDKA 2WCWA 2WCZA 2CV8A 2ZYZB 3P1YA 4QBLA 1HH1A 2OSTA 2INBA 2ZYZA 1RLVA 3FOVA 1Y88A 1ZP7A 1F1ZA 1OB9A 1R11A 3P1ZB 2FCOA 3DNXA 1IPIA 1GEFA 1R0VA 1T0FA 2WIWA 3P1ZA 4TKKA 2VLDA 1RZNA 4QBOA 2WJ0A
chains in the Genus database with same CATH superfamily
3THXA 3IEYA 4TKDA 2Z0RA 1E3MA 2GW6A 4G6VA 1WBBA 3AJVA 3BT7A 5FDKA 2VS1A 2CV8A 2O8BA 4QBLA 2DBSA 1HH1A 4E6ZA 2O8FA 1UWVA 1OH7A 1F1ZA 2O8EB 2IXSA 2FKHB 3DNXA 2O8CB 2BH2A 1YNMA 1R0VA 3THWA 1WBDA 2VLDA 1RZNA 2FLCA 4DAVA 2WIZA 2GJWA 2OKFA 2EO0A 2WCWA 2WCZA 3P1YA 2OSTA 2INBA 4EV1A 3ZLJA 3P1ZB 2W8MA 1GEFA 3THXB 2O8EA 2FL3A 2O8CA 4QBOA 3IF0X 2O8DB 1NG9A 4QBNA 2FKCA 4G6UA 4LQEA 4FZ2A 2ZYZB 3THYB 2FZ4A 1RLVA 4ZQUA 1Y88A 1ZP7A 4DA2A 4DAPA 1OH8A 1R11A 2WTUA 2FWRA 1WB9A 1T0FA 3K0SA 3IEYB 3P1ZA 2WIWA 2WJ0A 3AJVB 1A79A 1OH6A 1OB8A 1OH5A 1XMXA 2O8BB 2O8DA 1Y1OA 2O8FB 1FW6A 2ZYZA 1EWQA 3THYA 1NNEA 3FOVA 2JJQA 2CZRA 1OB9A 3THWB 2FCOA 1IPIA 4TKKA 1W7AA
chains in the Genus database with same CATH topology
3AJVB 1A79A 3IEYA 1OB8A 2Z0RA 3IF0X 4TKDA 4DAVA 2GW6A 4G6VA 4QBNA 2FKCA 1XMXA 3AJVA 2WIZA 2GJWA 4G6UA 2OKFA 4LQEA 2EO0A 3BT7A 4FZ2A 1Y1OA 5FDKA 2VS1A 2WCWA 2WCZA 2CV8A 2ZYZB 3P1YA 4QBLA 2DBSA 1HH1A 4E6ZA 2OSTA 2INBA 2ZYZA 4EV1A 1RLVA 1UWVA 3FOVA 2JJQA 1Y88A 4ZQUA 1ZP7A 1F1ZA 4DA2A 2CZRA 4DAPA 1OB9A 1R11A 3P1ZB 2IXSA 2FKHB 2FCOA 2W8MA 3DNXA 1IPIA 1GEFA 2FLCA 2BH2A 1YNMA 1R0VA 1T0FA 3IEYB 3P1ZA 4TKKA 2VLDA 2WIWA 2FL3A 1RZNA 4QBOA 2WJ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AJV B;  1A79 A;  3IEY A;  1OB8 A;  4TKD A;  2GW6 A;  4QBN A;  1XMX A;  3AJV A;  2WIZ A;  2GJW A;  2OKF A;  2EO0 A;  4FZ2 A;  1Y1O A;  5FDK A;  2WCW A;  2WCZ A;  2CV8 A;  2ZYZ B;  3P1Y A;  4QBL A;  1HH1 A;  2OST A;  2INB A;  2ZYZ A;  1RLV A;  3FOV A;  1Y88 A;  1ZP7 A;  1F1Z A;  1OB9 A;  1R11 A;  3P1Z B;  2FCO A;  3DNX A;  1IPI A;  1GEF A;  1R0V A;  1T0F A;  2WIW A;  3P1Z A;  4TKK A;  2VLD A;  1RZN A;  4QBO A;  2WJ0 A; 
#chains in the Genus database with same CATH topology
 3THX A;  3IEY A;  4TKD A;  2Z0R A;  1E3M A;  2GW6 A;  4G6V A;  1WBB A;  3AJV A;  3BT7 A;  5FDK A;  2VS1 A;  2CV8 A;  2O8B A;  4QBL A;  2DBS A;  1HH1 A;  4E6Z A;  2O8F A;  1UWV A;  1OH7 A;  1F1Z A;  2O8E B;  2IXS A;  2FKH B;  3DNX A;  2O8C B;  2BH2 A;  1YNM A;  1R0V A;  3THW A;  1WBD A;  2VLD A;  1RZN A;  2FLC A;  4DAV A;  2WIZ A;  2GJW A;  2OKF A;  2EO0 A;  2WCW A;  2WCZ A;  3P1Y A;  2OST A;  2INB A;  4EV1 A;  3ZLJ A;  3P1Z B;  2W8M A;  1GEF A;  3THX B;  2O8E A;  2FL3 A;  2O8C A;  4QBO A;  3IF0 X;  2O8D B;  1NG9 A;  4QBN A;  2FKC A;  4G6U A;  4LQE A;  4FZ2 A;  2ZYZ B;  3THY B;  2FZ4 A;  1RLV A;  4ZQU A;  1Y88 A;  1ZP7 A;  4DA2 A;  4DAP A;  1OH8 A;  1R11 A;  2WTU A;  2FWR A;  1WB9 A;  1T0F A;  3K0S A;  3IEY B;  3P1Z A;  2WIW A;  2WJ0 A;  3AJV B;  1A79 A;  1OH6 A;  1OB8 A;  1OH5 A;  1XMX A;  2O8B B;  2O8D A;  1Y1O A;  2O8F B;  1FW6 A;  2ZYZ A;  1EWQ A;  3THY A;  1NNE A;  3FOV A;  2JJQ A;  2CZR A;  1OB9 A;  3THW B;  2FCO A;  1IPI A;  4TKK A;  1W7A A; 
#chains in the Genus database with same CATH homology
 3AJV B;  1A79 A;  3IEY A;  1OB8 A;  2Z0R A;  3IF0 X;  4TKD A;  4DAV A;  2GW6 A;  4G6V A;  4QBN A;  2FKC A;  1XMX A;  3AJV A;  2WIZ A;  2GJW A;  4G6U A;  2OKF A;  4LQE A;  2EO0 A;  3BT7 A;  4FZ2 A;  1Y1O A;  5FDK A;  2VS1 A;  2WCW A;  2WCZ A;  2CV8 A;  2ZYZ B;  3P1Y A;  4QBL A;  2DBS A;  1HH1 A;  4E6Z A;  2OST A;  2INB A;  2ZYZ A;  4EV1 A;  1RLV A;  1UWV A;  3FOV A;  2JJQ A;  1Y88 A;  4ZQU A;  1ZP7 A;  1F1Z A;  4DA2 A;  2CZR A;  4DAP A;  1OB9 A;  1R11 A;  3P1Z B;  2IXS A;  2FKH B;  2FCO A;  2W8M A;  3DNX A;  1IPI A;  1GEF A;  2FLC A;  2BH2 A;  1YNM A;  1R0V A;  1T0F A;  3IEY B;  3P1Z A;  4TKK A;  2VLD A;  2WIW A;  2FL3 A;  1RZN A;  4QBO A;  2WJ0 A; 
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