3P34A

Polo-like kinase i polo-box domain in complex with mqsptpl phosphopeptide
Total Genus 75
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
230
structure length
230
Chain Sequence
GPLGSPEFDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serine/threonine-protein kinase PLK1
publication title From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 75
structure length 230
sequence length 230
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2010-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3p34A02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3p34A01
4WHHA 3P37A 4O56A 4RCPA 4DFWA 3HIHA 4H71A 3Q1IA 1Q4KA 2OJXA 4E9CA 4E9DA 4XB0A 4WHKA 2N19A 2OGQA 1Q4OA 3BZIA 4J7BB 4WHLA 4RS6A 4H5XA 4X9RA 3P36A 4LKLA 3HIKA 4X9WA 5DNJA 3P35A 4E67A 1UMWA 4HY2A 3C5LA 5J19A 4YYPA 4O6WA 3P2ZA 5DMSA 3P2WA 4O9WA 3P34A 5LHZA 5DMVC 3FVHA 4HCOA 3RQ7A 4X9VA 4HABA 4LKMA
chains in the Genus database with same CATH superfamily
1P49A 4O56A 3HFDA 5AJ9A 1AUKA 1E2SP 3Q1IA 3HMJG 4CXSA 4N7ZA 1Q4OA 3BZIA 1E2TA 4H5XA 4FDIA 3P36A 4LKLA 1UMWA 5J19A 3P2WA 5DMVC 4N7VA 2VKZG 3GYWA 3P37A 4RCPA 3LM3A 4H71A 3GYVA 4E9CA 4G7NA 4CXKA 4NK7A 4J7BB 4RS6A 4X9RA 1N2KA 3P35A 4YYPA 4NKBA 5DMSA 1F32A 1HDHA 4CYRA 4LKMA 4HABA 4WHHA 4DFWA 2E50A 3HIHA 4FDJA 2I9ZA 2OJXA 3KDRA 4XB0A 3FS3A 4WHKA 2OGQA 3ED4A 1N2LA 2IA9A 3HIKA 1E3CP 3LXQA 4HY2A 4O6WA 3P34A 4HCOA 3RQ7A 4X9VA 2I9XA 1F34B 2QZUA 5DAYA 4CXUA 2UV8G 1Q4KA 4E9DA 1FSUA 2N19A 4WHLA 4E67A 4X9WA 5DNJA 3C5LA 1E33P 3P2ZA 4O9WA 5LHZA 1E1ZP 3FVHA 4N9JA 1A87A 4CYSA
chains in the Genus database with same CATH topology
4WHHA 3P37A 4O56A 4RCPA 4DFWA 3HIHA 4H71A 3Q1IA 1Q4KA 2OJXA 4E9CA 4E9DA 4XB0A 4WHKA 2N19A 2OGQA 1Q4OA 3BZIA 4J7BB 4WHLA 4RS6A 4H5XA 4X9RA 3P36A 4LKLA 3HIKA 4X9WA 5DNJA 3P35A 4E67A 1UMWA 4HY2A 3C5LA 5J19A 4YYPA 4O6WA 3P2ZA 5DMSA 3P2WA 4O9WA 3P34A 5LHZA 5DMVC 3FVHA 4HCOA 3RQ7A 4X9VA 4HABA 4LKMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WHH A;  3P37 A;  4O56 A;  4RCP A;  4DFW A;  3HIH A;  4H71 A;  3Q1I A;  1Q4K A;  2OJX A;  4E9C A;  4E9D A;  4XB0 A;  4WHK A;  2N19 A;  2OGQ A;  1Q4O A;  3BZI A;  4J7B B;  4WHL A;  4RS6 A;  4H5X A;  4X9R A;  3P36 A;  4LKL A;  3HIK A;  4X9W A;  5DNJ A;  3P35 A;  4E67 A;  1UMW A;  4HY2 A;  3C5L A;  5J19 A;  4YYP A;  4O6W A;  3P2Z A;  5DMS A;  3P2W A;  4O9W A;  3P34 A;  5LHZ A;  5DMV C;  3FVH A;  4HCO A;  3RQ7 A;  4X9V A;  4HAB A;  4LKM A; 
#chains in the Genus database with same CATH topology
 1P49 A;  4O56 A;  3HFD A;  5AJ9 A;  1AUK A;  1E2S P;  3Q1I A;  3HMJ G;  4CXS A;  4N7Z A;  1Q4O A;  3BZI A;  1E2T A;  4H5X A;  4FDI A;  3P36 A;  4LKL A;  1UMW A;  5J19 A;  3P2W A;  5DMV C;  4N7V A;  2VKZ G;  3GYW A;  3P37 A;  4RCP A;  3LM3 A;  4H71 A;  3GYV A;  4E9C A;  4G7N A;  4CXK A;  4NK7 A;  4J7B B;  4RS6 A;  4X9R A;  1N2K A;  3P35 A;  4YYP A;  4NKB A;  5DMS A;  1F32 A;  1HDH A;  4CYR A;  4LKM A;  4HAB A;  4WHH A;  4DFW A;  2E50 A;  3HIH A;  4FDJ A;  2I9Z A;  2OJX A;  3KDR A;  4XB0 A;  3FS3 A;  4WHK A;  2OGQ A;  3ED4 A;  1N2L A;  2IA9 A;  3HIK A;  1E3C P;  3LXQ A;  4HY2 A;  4O6W A;  3P34 A;  4HCO A;  3RQ7 A;  4X9V A;  2I9X A;  1F34 B;  2QZU A;  5DAY A;  4CXU A;  2UV8 G;  1Q4K A;  4E9D A;  1FSU A;  2N19 A;  4WHL A;  4E67 A;  4X9W A;  5DNJ A;  3C5L A;  1E33 P;  3P2Z A;  4O9W A;  5LHZ A;  1E1Z P;  3FVH A;  4N9J A;  1A87 A;  4CYS A; 
#chains in the Genus database with same CATH homology
 4WHH A;  3P37 A;  4O56 A;  4RCP A;  4DFW A;  3HIH A;  4H71 A;  3Q1I A;  1Q4K A;  2OJX A;  4E9C A;  4E9D A;  4XB0 A;  4WHK A;  2N19 A;  2OGQ A;  1Q4O A;  3BZI A;  4J7B B;  4WHL A;  4RS6 A;  4H5X A;  4X9R A;  3P36 A;  4LKL A;  3HIK A;  4X9W A;  5DNJ A;  3P35 A;  4E67 A;  1UMW A;  4HY2 A;  3C5L A;  5J19 A;  4YYP A;  4O6W A;  3P2Z A;  5DMS A;  3P2W A;  4O9W A;  3P34 A;  5LHZ A;  5DMV C;  3FVH A;  4HCO A;  3RQ7 A;  4X9V A;  4HAB A;  4LKM A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...