3P34A

Polo-like kinase i polo-box domain in complex with mqsptpl phosphopeptide
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
230
structure length
230
Chain Sequence
b'GPLGSPEFDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLS'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serine/threonine-protein kinase PLK1
publication title From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 75
structure length 230
sequence length 230
ec nomenclature ec 2.7.11.21: Polo kinase.
pdb deposition date 2010-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00659 POLO_box POLO box duplicated region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3p34A02
3.30.1120.30 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain POLO box domain 3p34A01
4WHHA 3BZIA 4HCOA 4RS6A 4DFWA 3P2ZA 4X9WA 3P36A 3RQ7A 4E67A 4O56A 1UMWA 5DNJA 4X9VA 4RCPA 2OGQA 4J7BB 4WHKA 3HIKA 4E9DA 4HY2A 3Q1IA 4LKLA 3P34A 4XB0A 1Q4KA 2N19A 5LHZA 3HIHA 3P2WA 3P35A 4X9RA 4E9CA 5DMVC 4LKMA 2OJXA 4H71A 4HABA 3C5LA 3FVHA 4YYPA 1Q4OA 4WHLA 5DMSA 4O6WA 4O9WA 4H5XA 3P37A 5J19A
chains in the Genus database with same CATH superfamily
4CXKA 4X9WA 4O56A 2UV8G 4RCPA 2OGQA 3HIKA 4HY2A 3Q1IA 2QZUA 4LKLA 3P34A 4XB0A 3LXQA 1F34B 5DMVC 4LKMA 4HABA 4O6WA 2E50A 4FDJA 5J19A 1FSUA 3P36A 4E67A 5AJ9A 5DNJA 4X9VA 4CYSA 4WHKA 5DAYA 1F32A 1A87A 1P49A 1N2LA 3GYVA 4N7VA 1HDHA 3GYWA 2IA9A 1AUKA 4WHHA 3BZIA 4RS6A 3P2ZA 3LM3A 1N2KA 1UMWA 2VKZG 4FDIA 3KDRA 1Q4KA 4G7NA 4CYRA 3HIHA 3P35A 4X9RA 4N7ZA 2OJXA 3C5LA 3FVHA 4NKBA 1Q4OA 4WHLA 2I9ZA 3ED4A 1E2TA 1E1ZP 1E33P 4HCOA 4DFWA 3RQ7A 4N9JA 3HMJG 4J7BB 4E9DA 2I9XA 2N19A 5LHZA 3P2WA 1E3CP 3FS3A 4E9CA 4H71A 4NK7A 4YYPA 4CXUA 5DMSA 1E2SP 4O9WA 4H5XA 3P37A 3HFDA 4CXSA
chains in the Genus database with same CATH topology
4WHHA 3BZIA 4HCOA 4RS6A 4DFWA 3P2ZA 4X9WA 3P36A 3RQ7A 4E67A 4O56A 1UMWA 5DNJA 4X9VA 4RCPA 2OGQA 4J7BB 4WHKA 3HIKA 4E9DA 4HY2A 3Q1IA 4LKLA 3P34A 4XB0A 1Q4KA 2N19A 5LHZA 3HIHA 3P2WA 3P35A 4X9RA 4E9CA 5DMVC 4LKMA 2OJXA 4H71A 4HABA 3C5LA 3FVHA 4YYPA 1Q4OA 4WHLA 5DMSA 4O6WA 4O9WA 4H5XA 3P37A 5J19A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WHH A;  3BZI A;  4HCO A;  4RS6 A;  4DFW A;  3P2Z A;  4X9W A;  3P36 A;  3RQ7 A;  4E67 A;  4O56 A;  1UMW A;  5DNJ A;  4X9V A;  4RCP A;  2OGQ A;  4J7B B;  4WHK A;  3HIK A;  4E9D A;  4HY2 A;  3Q1I A;  4LKL A;  3P34 A;  4XB0 A;  1Q4K A;  2N19 A;  5LHZ A;  3HIH A;  3P2W A;  3P35 A;  4X9R A;  4E9C A;  5DMV C;  4LKM A;  2OJX A;  4H71 A;  4HAB A;  3C5L A;  3FVH A;  4YYP A;  1Q4O A;  4WHL A;  5DMS A;  4O6W A;  4O9W A;  4H5X A;  3P37 A;  5J19 A; 
#chains in the Genus database with same CATH topology
 4CXK A;  4X9W A;  4O56 A;  2UV8 G;  4RCP A;  2OGQ A;  3HIK A;  4HY2 A;  3Q1I A;  2QZU A;  4LKL A;  3P34 A;  4XB0 A;  3LXQ A;  1F34 B;  5DMV C;  4LKM A;  4HAB A;  4O6W A;  2E50 A;  4FDJ A;  5J19 A;  1FSU A;  3P36 A;  4E67 A;  5AJ9 A;  5DNJ A;  4X9V A;  4CYS A;  4WHK A;  5DAY A;  1F32 A;  1A87 A;  1P49 A;  1N2L A;  3GYV A;  4N7V A;  1HDH A;  3GYW A;  2IA9 A;  1AUK A;  4WHH A;  3BZI A;  4RS6 A;  3P2Z A;  3LM3 A;  1N2K A;  1UMW A;  2VKZ G;  4FDI A;  3KDR A;  1Q4K A;  4G7N A;  4CYR A;  3HIH A;  3P35 A;  4X9R A;  4N7Z A;  2OJX A;  3C5L A;  3FVH A;  4NKB A;  1Q4O A;  4WHL A;  2I9Z A;  3ED4 A;  1E2T A;  1E1Z P;  1E33 P;  4HCO A;  4DFW A;  3RQ7 A;  4N9J A;  3HMJ G;  4J7B B;  4E9D A;  2I9X A;  2N19 A;  5LHZ A;  3P2W A;  1E3C P;  3FS3 A;  4E9C A;  4H71 A;  4NK7 A;  4YYP A;  4CXU A;  5DMS A;  1E2S P;  4O9W A;  4H5X A;  3P37 A;  3HFD A;  4CXS A; 
#chains in the Genus database with same CATH homology
 4WHH A;  3BZI A;  4HCO A;  4RS6 A;  4DFW A;  3P2Z A;  4X9W A;  3P36 A;  3RQ7 A;  4E67 A;  4O56 A;  1UMW A;  5DNJ A;  4X9V A;  4RCP A;  2OGQ A;  4J7B B;  4WHK A;  3HIK A;  4E9D A;  4HY2 A;  3Q1I A;  4LKL A;  3P34 A;  4XB0 A;  1Q4K A;  2N19 A;  5LHZ A;  3HIH A;  3P2W A;  3P35 A;  4X9R A;  4E9C A;  5DMV C;  4LKM A;  2OJX A;  4H71 A;  4HAB A;  3C5L A;  3FVH A;  4YYP A;  1Q4O A;  4WHL A;  5DMS A;  4O6W A;  4O9W A;  4H5X A;  3P37 A;  5J19 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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