3P3EA

Crystal structure of the pseudomonas aeruginosa lpxc/lpc-009 complex
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
297
structure length
297
Chain Sequence
MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
total genus 83
structure length 297
sequence length 297
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2010-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3p3eA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3p3eA02
2IESA 3P3CA 5DRQA 3P3GA 2IERA 4ISAA 3PS1A 4LCFA 4IS9A 4FW5A 1P42A 5DROA 3PS2A 4FW6A 4FW3A 4FW4A 1YH8A 4LCGA 1YHCA 4FW7A 2JT2A 3PS3A 4U3BA 1XXEA 3U1YA 2GO3A 3P3EA 4OZEA 4OKGA 4MDTA 2GO4A 4U3DA 2J65A 4LCHA 3P76A 2O3ZA 3NZKA 2VESA 4J3DA 5DRRA 4MQYA 5DRPA 3UHMA
chains in the Genus database with same CATH superfamily
4MU3A 4HACA 2HHHI 1N32E 3M7NG 5LMUE 2IOPA 3DD6A 1ZM3A 2XEXA 2C37B 2VQFI 4GQUA 3WU3A 4HXZA 4Z7YA 4DR5E 4JI2I 4M1KA 3J81C 4DR7I 3QT5A 1H72C 3B78A 2GO3A 4LF6E 2NN6F 2BA0G 1OYRA 4OKGA 5EL9A 2CVEA 1R6LA 4YY3I 1UEKA 1ELOA 1Z0TA 3B82A 3QT6A 5BR8I 3UHMA 4JV5E 2IESA 3HULA 1KKHA 1HNWE 1XMQI 2Z5CA 5DNXA 2PNZA 5K36A 4IZKA 1IBLI 4LCFA 2NN6D 2F4VI 1Y5YA 2E1RA 1NHHA 3HJCA 4FW6A 4BA2B 3J80C 4X65I 1XNRI 1Z0BA 4JI8I 2Z5BA 3H1CA 5JEAC 3U1YA 5K36E 1Z0WA 1HNXE 1N0UA 4AIMA 1DARA 5LMNI 2VQEE 2C38A 1UDQA 3PRYA 4X64E 5DRPA 4B3ME 4DR3E 1XNQE 2IERA 2BA1G 1N33I 2OI2A 4JI0I 4DV5E 3ZKDA 4DV1E 1N34I 1NHJA 3PS2A 4LFAE 3L7ZB 3ZZTA 4OX9E 4JI7E 1KTVA 4B3RE 3T1YI 2PO2A 4U3BA 4P7AA 2UU9I 4USMA 1OYPA 5A2QQ 1ZXNA 1UDSA 2O1TA 4XTJA 3ZM7A 4DXLA 3T1HE 1HNZE 2HKEA 3GONA 5GMDA 4BA1B 4X64I 4B3TI 2NN6B 1ZM2A 4IZJB 1XNQI 3QT7A 2AJ4A 2CGEA 2UXBE 3JAMQ 3ZZUA 1Z5AA 2VF3A 2X7IA 1RHYA 4JI5I 4QNJA 4KHPE 2C39B 1KIJA 2BA0D 4DV3I 3NZKA 4LOMA 4YHHE 1HR0I 1FKAE 4LF8I 4DV0I 1RR9A 1H74A 1PKPA 4LFBI 4GKJE 4JI3I 3OTOE 1P42A 4NBQA 2HFUA 5JEAA 2A2CA 4MYUA 4AQYE 2UUCE 4PU9A 4K0KE 4U3DA 3V2UC 2O1UA 4PRXA 4DV7I 2E5LE 5DRRA 5JEAE 2WP8B 1RREA 2C37A 2F1DA 4IS9A 1J5EE 2BA1D 4LFCI 2NN6C 5A2QC 1UDNA 4IFDF 4DV2E 4MYTA 1N36I 4LF7E 1XMOI 3J7AG 1XXEA 2V2QA 2R3VA 4FWHA 3OTOI 4DPTA 1IBKI 1H73A 3P76A 1ZXMA 4MQYA 4DV4E 4IFDD 1D6TA 1Y4SA 2HKJA 4AQYI 1S4EA 2JEBB 2BM0A 3JAMC 1B62A 2JEAB 2E5LI 4IZJD 4BA2A 2DEJA 4FW9A 1FWKA 1E3HA 1N32I 5LMUI 1OJ4A 4JYAE 4GKKE 3WU5A 1I94E 1OYSA 5ELWA 1VI7A 4DUZE 1PIEA 4DR5I 2EFGA 3U1KA 4LPFA 2R42A 4LF6I 1XHKA 2Z5CB 4ED4A 2A2DA 4X66E 2HK3A 4JI4E 5C0XF 4B3SE 3L7ZA 4P52A 2PO1B 4DV4I 3B4TA 4JV5I 4FW3A 2GQ0A 3PYFA 2GS8A 4OO1F 1YH8A 1IBME 4LF9E 1HNWI 2Z5BB 4JI6E 4NXME 4DV6E 2Q2EB 5IT9Q 4UTGA 5C0XD 2O3ZA 3LNUA 4FN5A 1USUA 4DR4E 4N3OA 4OO1D 1I94I 5IWAE 4MU1A 4UT4A 1HNXI 3H4LA 4IFDB 4BA1A 4JI1E 2VQEI 2NN6A 3CDIA 4IZJA 2UXDE 4RPFA 4X62E 2PO0B 4B3MI 5GMEA 4DR3I 2WNRB 1E3PA 3WU4A 2Z5EA 1FJGE 4JI4I 4B3SI 3B8HA 4LF5E 2C39A 2JE6B 4WUDA 4DV5I 4DV1I 2NN6E 3LPSA 3GCMA 3QT8A 4KQVA 4LFAI 4OX9I 3V5RA 2ZITA 4DUYE 2O1VA 4JI7I 4B3RI 4LF4E 2BR2B 4DR1E 4MU0A 5DRQA 1H7SA 1ZM4A 1FI4A 1A6FA 2X36A 1H7UA 4DV6I 1Z0EA 4NXNE 3ZZ0A 1MU5A 2BM1A 3T1HI 5K36F 1HNZI 3Q1QA 2CZ9A 2ZM6E 1BKNA 1MX0A 3Q6NA 5FLXC 1HK7A 2GO4A 2VQFE 2UXBI 2WP8A 5C0XB 4JI2E 3P3GA 5K36D 4OO1B 4KHPI 4IFDC 4DU8A 5EKWA 4LF4I 4DPYA 4YHHI 2IOQA 5IT9C 4FWGA 4NXNI 4R1FA 3P3EA 1XMQE 4GKJI 4MDTA 3GMEA 3D4JA 5DNLA 4LCHA 4MU4A 4J3DA 2VESA 3WU6A 4OZEA 1FNMA 4X65E 1QZRA 2ZM6I 1XNRE 1Y60A 3PYGA 4ZVIA 4HACB 1Z5CA 4JI8E 2JEBA 2CG9A 2JEAA 2PNLA 2UUCI 3PS1A 4K0KI 4WUBA 4FW5A 5LMNE 4FW4A 2UUAE 4LCGA 1NHIA 4AIDA 4DPWA 3HKMA 1S16A 1J5EI 2J7KA 1N33E 4DR6E 4JI0E 1N34E 2V2VA 2DEIA 4DV2I 5C0XC 4LF7I 3K1JA 1WUUA 5FLXQ 4HY1A 3T1YE 4DPXA 4OO1C 2UU9E 5K36B 2PNZB 1Z5BA 3PYDA 4DR2E 4IZKB 2PO1A 4DU7A 4I3HA 5DROA 1Z59A 3CDJA 4AM3A 2UUBE 1Z0CA 2PNMA 2WW4A 2NPFA 3M85G 2UUAI 5JEAF 1VISA 4B3TE 2C38B 3Q6MA 4JYAI 1FWLA 3GLLA 5LL6R 4IFDA 4GKKI 1U2RA 4DR6I 4DUZI 3CWVA 4JI5E 1Z0VA 3J7AM 2PO0A 2WNRA 4DV3E 4URLA 5JEAD 1NZ0A 5L3JA 4IFDE 1HR0E 4LF8E 2JE6A 2ZBKB 4DV0E 2PO2B 4DR2I 4X66I 4Z7CA 5FWKA 4LFBE 1Z0GA 3J81Q 1Y6ZA 4WUCA 4JI3E 4USKA 3K85A 2UUBI 2BR2A 1IBMI 3PYEA 4LF9I 1K47A 4JI6I 4NXMI 4ISAA 3ZKBA 3M7ND 2UXCE 3KRNA 4PRVA 5K36C 3M6AA 1R6MA 1USVA 2HFSA 4DV7E 4DR4I 2O1WA 2V2ZA 1YHCA 5IWAI 1EA6A 2JT2A 2HK2A 1EI1A 1PVGA 2HHHE 4JG4A 4JI1I 3J80Q 1N0VC 2UXDI 1MG7A 2AE8A 4X62I 4LFCE 5C0XA 1FJGI 3P3CA 1B63A 1N36E 4LF5I 4OO1A 4FWDA 1XMOE 3K17A 3F0NA 4DR7E 4QNKA 4HYMA 1IBKE 2V34A 4DUYI 4YY3E 5C0XE 4DR1I 2V8PA 5BR8E 4FW7A 4OO1E 1ZM9A 5JEAB 3PS3A 2UXCI 2LJPA 2BV3A 4EMDA 3LTOA 4DPUA 2J65A 3P06A 1IBLE 1UDOA 1KVKA 1Y4UA 3M85D 2F4VE
chains in the Genus database with same CATH topology
2IESA 3P3CA 5DRQA 3P3GA 2IERA 4ISAA 3PS1A 4LCFA 4IS9A 4FW5A 1P42A 5DROA 3PS2A 4FW6A 4FW3A 4FW4A 1YH8A 4LCGA 1YHCA 4FW7A 2JT2A 3PS3A 4U3BA 1XXEA 3U1YA 2GO3A 3P3EA 4OZEA 4OKGA 4MDTA 2GO4A 4U3DA 2J65A 4LCHA 3P76A 2O3ZA 3NZKA 2VESA 4J3DA 5DRRA 4MQYA 5DRPA 3UHMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IES A;  3P3C A;  5DRQ A;  3P3G A;  2IER A;  4ISA A;  3PS1 A;  4LCF A;  4IS9 A;  4FW5 A;  1P42 A;  5DRO A;  3PS2 A;  4FW6 A;  4FW3 A;  4FW4 A;  1YH8 A;  4LCG A;  1YHC A;  4FW7 A;  2JT2 A;  3PS3 A;  4U3B A;  1XXE A;  3U1Y A;  2GO3 A;  3P3E A;  4OZE A;  4OKG A;  4MDT A;  2GO4 A;  4U3D A;  2J65 A;  4LCH A;  3P76 A;  2O3Z A;  3NZK A;  2VES A;  4J3D A;  5DRR A;  4MQY A;  5DRP A;  3UHM A; 
#chains in the Genus database with same CATH topology
 4MU3 A;  4HAC A;  2HHH I;  1N32 E;  3M7N G;  5LMU E;  2IOP A;  3DD6 A;  1ZM3 A;  2XEX A;  2C37 B;  2VQF I;  4GQU A;  3WU3 A;  4HXZ A;  4Z7Y A;  4DR5 E;  4JI2 I;  4M1K A;  3J81 C;  4DR7 I;  3QT5 A;  1H72 C;  3B78 A;  2GO3 A;  4LF6 E;  2NN6 F;  2BA0 G;  1OYR A;  4OKG A;  5EL9 A;  2CVE A;  1R6L A;  4YY3 I;  1UEK A;  1ELO A;  1Z0T A;  3B82 A;  3QT6 A;  5BR8 I;  3UHM A;  4JV5 E;  2IES A;  3HUL A;  1KKH A;  1HNW E;  1XMQ I;  2Z5C A;  5DNX A;  2PNZ A;  5K36 A;  4IZK A;  1IBL I;  4LCF A;  2NN6 D;  2F4V I;  1Y5Y A;  2E1R A;  1NHH A;  3HJC A;  4FW6 A;  4BA2 B;  3J80 C;  4X65 I;  1XNR I;  1Z0B A;  4JI8 I;  2Z5B A;  3H1C A;  5JEA C;  3U1Y A;  5K36 E;  1Z0W A;  1HNX E;  1N0U A;  4AIM A;  1DAR A;  5LMN I;  2VQE E;  2C38 A;  1UDQ A;  3PRY A;  4X64 E;  5DRP A;  4B3M E;  4DR3 E;  1XNQ E;  2IER A;  2BA1 G;  1N33 I;  2OI2 A;  4JI0 I;  4DV5 E;  3ZKD A;  4DV1 E;  1N34 I;  1NHJ A;  3PS2 A;  4LFA E;  3L7Z B;  3ZZT A;  4OX9 E;  4JI7 E;  1KTV A;  4B3R E;  3T1Y I;  2PO2 A;  4U3B A;  4P7A A;  2UU9 I;  4USM A;  1OYP A;  5A2Q Q;  1ZXN A;  1UDS A;  2O1T A;  4XTJ A;  3ZM7 A;  4DXL A;  3T1H E;  1HNZ E;  2HKE A;  3GON A;  5GMD A;  4BA1 B;  4X64 I;  4B3T I;  2NN6 B;  1ZM2 A;  4IZJ B;  1XNQ I;  3QT7 A;  2AJ4 A;  2CGE A;  2UXB E;  3JAM Q;  3ZZU A;  1Z5A A;  2VF3 A;  2X7I A;  1RHY A;  4JI5 I;  4QNJ A;  4KHP E;  2C39 B;  1KIJ A;  2BA0 D;  4DV3 I;  3NZK A;  4LOM A;  4YHH E;  1HR0 I;  1FKA E;  4LF8 I;  4DV0 I;  1RR9 A;  1H74 A;  1PKP A;  4LFB I;  4GKJ E;  4JI3 I;  3OTO E;  1P42 A;  4NBQ A;  2HFU A;  5JEA A;  2A2C A;  4MYU A;  4AQY E;  2UUC E;  4PU9 A;  4K0K E;  4U3D A;  3V2U C;  2O1U A;  4PRX A;  4DV7 I;  2E5L E;  5DRR A;  5JEA E;  2WP8 B;  1RRE A;  2C37 A;  2F1D A;  4IS9 A;  1J5E E;  2BA1 D;  4LFC I;  2NN6 C;  5A2Q C;  1UDN A;  4IFD F;  4DV2 E;  4MYT A;  1N36 I;  4LF7 E;  1XMO I;  3J7A G;  1XXE A;  2V2Q A;  2R3V A;  4FWH A;  3OTO I;  4DPT A;  1IBK I;  1H73 A;  3P76 A;  1ZXM A;  4MQY A;  4DV4 E;  4IFD D;  1D6T A;  1Y4S A;  2HKJ A;  4AQY I;  1S4E A;  2JEB B;  2BM0 A;  3JAM C;  1B62 A;  2JEA B;  2E5L I;  4IZJ D;  4BA2 A;  2DEJ A;  4FW9 A;  1FWK A;  1E3H A;  1N32 I;  5LMU I;  1OJ4 A;  4JYA E;  4GKK E;  3WU5 A;  1I94 E;  1OYS A;  5ELW A;  1VI7 A;  4DUZ E;  1PIE A;  4DR5 I;  2EFG A;  3U1K A;  4LPF A;  2R42 A;  4LF6 I;  1XHK A;  2Z5C B;  4ED4 A;  2A2D A;  4X66 E;  2HK3 A;  4JI4 E;  5C0X F;  4B3S E;  3L7Z A;  4P52 A;  2PO1 B;  4DV4 I;  3B4T A;  4JV5 I;  4FW3 A;  2GQ0 A;  3PYF A;  2GS8 A;  4OO1 F;  1YH8 A;  1IBM E;  4LF9 E;  1HNW I;  2Z5B B;  4JI6 E;  4NXM E;  4DV6 E;  2Q2E B;  5IT9 Q;  4UTG A;  5C0X D;  2O3Z A;  3LNU A;  4FN5 A;  1USU A;  4DR4 E;  4N3O A;  4OO1 D;  1I94 I;  5IWA E;  4MU1 A;  4UT4 A;  1HNX I;  3H4L A;  4IFD B;  4BA1 A;  4JI1 E;  2VQE I;  2NN6 A;  3CDI A;  4IZJ A;  2UXD E;  4RPF A;  4X62 E;  2PO0 B;  4B3M I;  5GME A;  4DR3 I;  2WNR B;  1E3P A;  3WU4 A;  2Z5E A;  1FJG E;  4JI4 I;  4B3S I;  3B8H A;  4LF5 E;  2C39 A;  2JE6 B;  4WUD A;  4DV5 I;  4DV1 I;  2NN6 E;  3LPS A;  3GCM A;  3QT8 A;  4KQV A;  4LFA I;  4OX9 I;  3V5R A;  2ZIT A;  4DUY E;  2O1V A;  4JI7 I;  4B3R I;  4LF4 E;  2BR2 B;  4DR1 E;  4MU0 A;  5DRQ A;  1H7S A;  1ZM4 A;  1FI4 A;  1A6F A;  2X36 A;  1H7U A;  4DV6 I;  1Z0E A;  4NXN E;  3ZZ0 A;  1MU5 A;  2BM1 A;  3T1H I;  5K36 F;  1HNZ I;  3Q1Q A;  2CZ9 A;  2ZM6 E;  1BKN A;  1MX0 A;  3Q6N A;  5FLX C;  1HK7 A;  2GO4 A;  2VQF E;  2UXB I;  2WP8 A;  5C0X B;  4JI2 E;  3P3G A;  5K36 D;  4OO1 B;  4KHP I;  4IFD C;  4DU8 A;  5EKW A;  4LF4 I;  4DPY A;  4YHH I;  2IOQ A;  5IT9 C;  4FWG A;  4NXN I;  4R1F A;  3P3E A;  1XMQ E;  4GKJ I;  4MDT A;  3GME A;  3D4J A;  5DNL A;  4LCH A;  4MU4 A;  4J3D A;  2VES A;  3WU6 A;  4OZE A;  1FNM A;  4X65 E;  1QZR A;  2ZM6 I;  1XNR E;  1Y60 A;  3PYG A;  4ZVI A;  4HAC B;  1Z5C A;  4JI8 E;  2JEB A;  2CG9 A;  2JEA A;  2PNL A;  2UUC I;  3PS1 A;  4K0K I;  4WUB A;  4FW5 A;  5LMN E;  4FW4 A;  2UUA E;  4LCG A;  1NHI A;  4AID A;  4DPW A;  3HKM A;  1S16 A;  1J5E I;  2J7K A;  1N33 E;  4DR6 E;  4JI0 E;  1N34 E;  2V2V A;  2DEI A;  4DV2 I;  5C0X C;  4LF7 I;  3K1J A;  1WUU A;  5FLX Q;  4HY1 A;  3T1Y E;  4DPX A;  4OO1 C;  2UU9 E;  5K36 B;  2PNZ B;  1Z5B A;  3PYD A;  4DR2 E;  4IZK B;  2PO1 A;  4DU7 A;  4I3H A;  5DRO A;  1Z59 A;  3CDJ A;  4AM3 A;  2UUB E;  1Z0C A;  2PNM A;  2WW4 A;  2NPF A;  3M85 G;  2UUA I;  5JEA F;  1VIS A;  4B3T E;  2C38 B;  3Q6M A;  4JYA I;  1FWL A;  3GLL A;  5LL6 R;  4IFD A;  4GKK I;  1U2R A;  4DR6 I;  4DUZ I;  3CWV A;  4JI5 E;  1Z0V A;  3J7A M;  2PO0 A;  2WNR A;  4DV3 E;  4URL A;  5JEA D;  1NZ0 A;  5L3J A;  4IFD E;  1HR0 E;  4LF8 E;  2JE6 A;  2ZBK B;  4DV0 E;  2PO2 B;  4DR2 I;  4X66 I;  4Z7C A;  5FWK A;  4LFB E;  1Z0G A;  3J81 Q;  1Y6Z A;  4WUC A;  4JI3 E;  4USK A;  3K85 A;  2UUB I;  2BR2 A;  1IBM I;  3PYE A;  4LF9 I;  1K47 A;  4JI6 I;  4NXM I;  4ISA A;  3ZKB A;  3M7N D;  2UXC E;  3KRN A;  4PRV A;  5K36 C;  3M6A A;  1R6M A;  1USV A;  2HFS A;  4DV7 E;  4DR4 I;  2O1W A;  2V2Z A;  1YHC A;  5IWA I;  1EA6 A;  2JT2 A;  2HK2 A;  1EI1 A;  1PVG A;  2HHH E;  4JG4 A;  4JI1 I;  3J80 Q;  1N0V C;  2UXD I;  1MG7 A;  2AE8 A;  4X62 I;  4LFC E;  5C0X A;  1FJG I;  3P3C A;  1B63 A;  1N36 E;  4LF5 I;  4OO1 A;  4FWD A;  1XMO E;  3K17 A;  3F0N A;  4DR7 E;  4QNK A;  4HYM A;  1IBK E;  2V34 A;  4DUY I;  4YY3 E;  5C0X E;  4DR1 I;  2V8P A;  5BR8 E;  4FW7 A;  4OO1 E;  1ZM9 A;  5JEA B;  3PS3 A;  2UXC I;  2LJP A;  2BV3 A;  4EMD A;  3LTO A;  4DPU A;  2J65 A;  3P06 A;  1IBL E;  1UDO A;  1KVK A;  1Y4U A;  3M85 D;  2F4V E; 
#chains in the Genus database with same CATH homology
 2IES A;  3P3C A;  5DRQ A;  3P3G A;  2IER A;  4ISA A;  3PS1 A;  4LCF A;  4IS9 A;  4FW5 A;  1P42 A;  5DRO A;  3PS2 A;  4FW6 A;  4FW3 A;  4FW4 A;  1YH8 A;  4LCG A;  1YHC A;  4FW7 A;  2JT2 A;  3PS3 A;  4U3B A;  1XXE A;  3U1Y A;  2GO3 A;  3P3E A;  4OZE A;  4OKG A;  4MDT A;  2GO4 A;  4U3D A;  2J65 A;  4LCH A;  3P76 A;  2O3Z A;  3NZK A;  2VES A;  4J3D A;  5DRR A;  4MQY A;  5DRP A;  3UHM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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