3P3EA

Crystal structure of the pseudomonas aeruginosa lpxc/lpc-009 complex
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
297
structure length
297
Chain Sequence
MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 83
structure length 297
sequence length 297
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2010-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3p3eA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3p3eA02
4LCFA 1XXEA 4U3DA 4MQYA 3P76A 3NZKA 2IESA 1YH8A 3P3GA 3P3CA 4OZEA 4U3BA 3PS2A 4FW3A 2IERA 4ISAA 1P42A 4IS9A 4J3DA 2J65A 4FW6A 4OKGA 3PS3A 4MDTA 2VESA 4FW7A 2JT2A 2O3ZA 3U1YA 3P3EA 3UHMA 2GO4A 5DRPA 4LCGA 2GO3A 1YHCA 4FW5A 5DRQA 4LCHA 4FW4A 5DRRA 5DROA 3PS1A
chains in the Genus database with same CATH superfamily
4JI0I 3HKMA 4KQVA 1Z5BA 4DUZE 4XTJA 2UU9I 4JV5E 4DV5E 2HFUA 4MYUA 3ZZ0A 4YY3I 4DR2I 2JEBA 4P52A 4LF5I 2DEJA 3J7AM 3KRNA 3WU3A 4JYAI 2VQEI 4DV6E 1N36E 1YHCA 2J7KA 4DV3E 1XNQI 4GKKE 4JI8I 2UUCE 4X62I 4LCHA 4B3RE 4LF9E 4JI1I 4OO1B 2E5LI 2BA1D 4GQUA 3J80Q 4M1KA 1RR9A 4BA2A 2Q2EB 2E1RA 2V8PA 2UUBE 3OTOI 1EI1A 4AIDA 4NXNI 4AQYI 1UDQA 4IFDD 4LF9I 1RREA 3J81Q 5L3JA 4JI3I 2ZM6E 1H74A 1N36I 4GKKI 1KIJA 2BA0D 4U3DA 1Y5YA 4DV1E 2UXDE 3P76A 4DV1I 3J81C 2XEXA 2GS8A 4HY1A 2UUAE 4B3TE 1Z0VA 1K47A 4JI5I 4X65E 3QT5A 2C38B 4B3SE 1N33E 2J65A 2UXCI 4DU8A 4Z7CA 4DV5I 4K0KE 4DUZI 2UU9E 3V5RA 3UHMA 4LF4I 3GMEA 4KHPI 2X7IA 1H7SA 3GLLA 1PIEA 4DV0I 4LF6I 4UT4A 5IWAE 4MQYA 4DR4E 1J5EE 4DV7I 4B3MI 2V2ZA 4AM3A 2C37A 2HHHE 4DV6I 4LF8I 1UEKA 3P06A 2O1UA 3HULA 2R42A 1HK7A 4MU4A 4DR4I 3K17A 5C0XE 1FKAE 5C0XC 3WU6A 3B78A 1H7UA 4DR7E 3H4LA 2WP8B 1H72C 4YHHI 2WNRA 5A2QC 4WUBA 3M7NG 3J7AG 4BA1A 3LTOA 4JI7I 1OYRA 4LFAE 3PS2A 4JI5E 2PO0A 1P42A 3ZKBA 4JI4I 2JEAA 1ZM9A 5JEAD 4QNKA 1MG7A 4X64I 2JEAB 4NXME 1Z0TA 2PNZB 5IT9C 4ZVIA 4DUYE 2Z5EA 4I3HA 3GONA 4DPYA 2ZM6I 4DR1E 2ZITA 4BA1B 1FWLA 2Z5BA 1HR0I 5DROA 4B3SI 3ZKDA 1N33I 1XMQI 5FLXQ 1Z59A 4LFBI 2Z5CB 4JV5I 4AQYE 1FI4A 4NXNE 5EL9A 2WP8A 2LJPA 5FWKA 4JI6I 4FWGA 4DV2I 1ELOA 5K36D 1EA6A 4OX9E 1DARA 2NN6E 3JAMC 4JI4E 4MU0A 1I94I 2VESA 4EMDA 5BR8I 2BR2B 1XMOE 2X36A 5JEAA 2UUCI 5EKWA 3PRYA 3ZZTA 2CGEA 5DRQA 2UUBI 5DRRA 1VISA 1BKNA 2UXBE 2NN6A 2NPFA 2CG9A 5K36E 2V2VA 3NZKA 3Q6NA 2EFGA 2A2CA 4LF4E 2O1TA 2O1VA 4DPWA 2UXDI 4RPFA 4J3DA 4WUDA 1ZM3A 4PU9A 4JI8E 2BA0G 4JI2E 1ZXMA 2C39A 2OI2A 4LOMA 4OO1E 4MU1A 4LCGA 1Y60A 4PRVA 2PNLA 3T1HI 1HNWI 1U2RA 3OTOE 3PS1A 3L7ZA 1E3HA 1OYSA 2AE8A 1HNXI 4JI6E 3J80C 1IBKE 2ZBKB 3CWVA 4OX9I 1XMQE 2UXCE 3B82A 4FW6A 3PS3A 4YHHE 1E3PA 4MDTA 4X62E 1D6TA 2GQ0A 5JEAE 4DPTA 2PNZA 3U1YA 1KVKA 4LFCI 4JI1E 2V34A 3U1KA 4LF7E 1NHIA 4WUCA 5LMNI 2BV3A 4FWHA 1VI7A 5DNXA 3GCMA 4FW4A 1HR0E 1YH8A 2A2DA 2IOPA 4X66E 1Y4SA 1Y6ZA 5JEAF 1WUUA 2BR2A 1IBMI 5K36F 3P3GA 1KTVA 4DR2E 1XMOI 2CZ9A 3M85G 1HNZE 4LFCE 3T1YI 1XNRI 4DV4E 3PYEA 1XHKA 2F4VE 1N34I 3P3EA 4JI7E 4DR7I 4FN5A 2HK3A 3CDJA 3QT6A 3M7ND 3PYGA 2PO1B 2PO1A 1USVA 1FJGE 1B63A 4B3RI 1XXEA 1PKPA 4DR5E 3M6AA 1IBLE 1ZM2A 3F0NA 3LNUA 2HFSA 4DUYI 5IT9Q 1N0UA 4IZJB 1Z0BA 4FW3A 5ELWA 2BM1A 4GKJE 2AJ4A 4DPXA 2PNMA 4DXLA 4LFAI 1H73A 1USUA 4IZKB 5DRPA 2PO2A 2PO2B 1R6LA 2C38A 5A2QQ 1B62A 4LCFA 3HJCA 5JEAC 1NHHA 2CVEA 4IFDF 2IESA 4IFDB 3WU5A 2F1DA 1Z0GA 4DU7A 1Z0CA 1A6FA 3T1YE 1XNRE 1MU5A 3T1HE 4DR3E 3B8HA 4HACB 1R6MA 1IBME 4IFDC 4IZJD 2VF3A 1MX0A 4UTGA 3L7ZB 3V2UC 4USMA 1Z0EA 3K85A 4LF7I 4IFDA 4LF5E 5IWAI 4DV0E 3ZM7A 1OJ4A 4LFBE 3LPSA 4PRXA 4OO1A 4YY3E 1KKHA 4ED4A 4MU3A 3M85D 5C0XF 1UDNA 1HNXE 4R1FA 3QT7A 1FNMA 4LF6E 1I94E 2UUAI 4B3TI 4IZJA 2GO4A 4JYAE 1HNWE 5LL6R 1HNZI 1Y4UA 2PO0B 5JEAB 2JEBB 2VQFI 4LPFA 1NZ0A 2V2QA 4FWDA 3WU4A 4IFDE 5C0XA 4JI2I 3DD6A 4JI3E 4U3BA 5LMNE 3PYFA 4BA2B 3D4JA 1OYPA 4JI0E 3Q1QA 3B4TA 2WW4A 4NXMI 2UXBI 1S16A 1QZRA 2E5LE 4N3OA 4QNJA 4DV4I 2Z5BB 5K36B 5C0XB 4FW5A 2C39B 5LMUI 1ZM4A 5LMUE 4DV7E 5BR8E 4HACA 4B3ME 3CDIA 1Z5CA 3P3CA 4OZEA 2VQEE 3H1CA 4URLA 4DV2E 4ISAA 2NN6C 2JE6A 5FLXC 2NN6B 4OKGA 3ZZUA 4K0KI 3QT8A 2IOQA 2O3ZA 2GO3A 4DPUA 1XNQE 4DV3I 4LF8E 4HXZA 2HHHI 1S4EA 2WNRB 4DR6E 4GKJI 2VQFE 2O1WA 1Z5AA 2BA1G 5K36C 1N34E 1J5EI 5C0XD 1IBLI 4NBQA 2BM0A 1N32I 4IS9A 5GMDA 2Z5CA 4HYMA 2C37B 1N32E 4DR6I 2R3VA 2HK2A 4AIMA 3JAMQ 1ZXNA 4P7AA 4OO1C 2NN6F 2NN6D 2JE6B 4X65I 4OO1F 1NHJA 5GMEA 1Z0WA 4USKA 1PVGA 5DNLA 2HKJA 3Q6MA 4Z7YA 4JG4A 4DR5I 4IZKA 4DR1I 3PYDA 1UDOA 1N0VC 1IBKI 2DEIA 4X66I 1RHYA 2IERA 3K1JA 5K36A 4DR3I 1FJGI 4FW7A 4X64E 2JT2A 4MYTA 4KHPE 4FW9A 2HKEA 4OO1D 1UDSA 1FWKA 2F4VI
chains in the Genus database with same CATH topology
4LCFA 1XXEA 4U3DA 4MQYA 3P76A 3NZKA 2IESA 1YH8A 3P3GA 3P3CA 4OZEA 4U3BA 3PS2A 4FW3A 2IERA 4ISAA 1P42A 4IS9A 4J3DA 2J65A 4FW6A 4OKGA 3PS3A 4MDTA 2VESA 4FW7A 2JT2A 2O3ZA 3U1YA 3P3EA 3UHMA 2GO4A 5DRPA 4LCGA 2GO3A 1YHCA 4FW5A 5DRQA 4LCHA 4FW4A 5DRRA 5DROA 3PS1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LCF A;  1XXE A;  4U3D A;  4MQY A;  3P76 A;  3NZK A;  2IES A;  1YH8 A;  3P3G A;  3P3C A;  4OZE A;  4U3B A;  3PS2 A;  4FW3 A;  2IER A;  4ISA A;  1P42 A;  4IS9 A;  4J3D A;  2J65 A;  4FW6 A;  4OKG A;  3PS3 A;  4MDT A;  2VES A;  4FW7 A;  2JT2 A;  2O3Z A;  3U1Y A;  3P3E A;  3UHM A;  2GO4 A;  5DRP A;  4LCG A;  2GO3 A;  1YHC A;  4FW5 A;  5DRQ A;  4LCH A;  4FW4 A;  5DRR A;  5DRO A;  3PS1 A; 
#chains in the Genus database with same CATH topology
 4JI0 I;  3HKM A;  4KQV A;  1Z5B A;  4DUZ E;  4XTJ A;  2UU9 I;  4JV5 E;  4DV5 E;  2HFU A;  4MYU A;  3ZZ0 A;  4YY3 I;  4DR2 I;  2JEB A;  4P52 A;  4LF5 I;  2DEJ A;  3J7A M;  3KRN A;  3WU3 A;  4JYA I;  2VQE I;  4DV6 E;  1N36 E;  1YHC A;  2J7K A;  4DV3 E;  1XNQ I;  4GKK E;  4JI8 I;  2UUC E;  4X62 I;  4LCH A;  4B3R E;  4LF9 E;  4JI1 I;  4OO1 B;  2E5L I;  2BA1 D;  4GQU A;  3J80 Q;  4M1K A;  1RR9 A;  4BA2 A;  2Q2E B;  2E1R A;  2V8P A;  2UUB E;  3OTO I;  1EI1 A;  4AID A;  4NXN I;  4AQY I;  1UDQ A;  4IFD D;  4LF9 I;  1RRE A;  3J81 Q;  5L3J A;  4JI3 I;  2ZM6 E;  1H74 A;  1N36 I;  4GKK I;  1KIJ A;  2BA0 D;  4U3D A;  1Y5Y A;  4DV1 E;  2UXD E;  3P76 A;  4DV1 I;  3J81 C;  2XEX A;  2GS8 A;  4HY1 A;  2UUA E;  4B3T E;  1Z0V A;  1K47 A;  4JI5 I;  4X65 E;  3QT5 A;  2C38 B;  4B3S E;  1N33 E;  2J65 A;  2UXC I;  4DU8 A;  4Z7C A;  4DV5 I;  4K0K E;  4DUZ I;  2UU9 E;  3V5R A;  3UHM A;  4LF4 I;  3GME A;  4KHP I;  2X7I A;  1H7S A;  3GLL A;  1PIE A;  4DV0 I;  4LF6 I;  4UT4 A;  5IWA E;  4MQY A;  4DR4 E;  1J5E E;  4DV7 I;  4B3M I;  2V2Z A;  4AM3 A;  2C37 A;  2HHH E;  4DV6 I;  4LF8 I;  1UEK A;  3P06 A;  2O1U A;  3HUL A;  2R42 A;  1HK7 A;  4MU4 A;  4DR4 I;  3K17 A;  5C0X E;  1FKA E;  5C0X C;  3WU6 A;  3B78 A;  1H7U A;  4DR7 E;  3H4L A;  2WP8 B;  1H72 C;  4YHH I;  2WNR A;  5A2Q C;  4WUB A;  3M7N G;  3J7A G;  4BA1 A;  3LTO A;  4JI7 I;  1OYR A;  4LFA E;  3PS2 A;  4JI5 E;  2PO0 A;  1P42 A;  3ZKB A;  4JI4 I;  2JEA A;  1ZM9 A;  5JEA D;  4QNK A;  1MG7 A;  4X64 I;  2JEA B;  4NXM E;  1Z0T A;  2PNZ B;  5IT9 C;  4ZVI A;  4DUY E;  2Z5E A;  4I3H A;  3GON A;  4DPY A;  2ZM6 I;  4DR1 E;  2ZIT A;  4BA1 B;  1FWL A;  2Z5B A;  1HR0 I;  5DRO A;  4B3S I;  3ZKD A;  1N33 I;  1XMQ I;  5FLX Q;  1Z59 A;  4LFB I;  2Z5C B;  4JV5 I;  4AQY E;  1FI4 A;  4NXN E;  5EL9 A;  2WP8 A;  2LJP A;  5FWK A;  4JI6 I;  4FWG A;  4DV2 I;  1ELO A;  5K36 D;  1EA6 A;  4OX9 E;  1DAR A;  2NN6 E;  3JAM C;  4JI4 E;  4MU0 A;  1I94 I;  2VES A;  4EMD A;  5BR8 I;  2BR2 B;  1XMO E;  2X36 A;  5JEA A;  2UUC I;  5EKW A;  3PRY A;  3ZZT A;  2CGE A;  5DRQ A;  2UUB I;  5DRR A;  1VIS A;  1BKN A;  2UXB E;  2NN6 A;  2NPF A;  2CG9 A;  5K36 E;  2V2V A;  3NZK A;  3Q6N A;  2EFG A;  2A2C A;  4LF4 E;  2O1T A;  2O1V A;  4DPW A;  2UXD I;  4RPF A;  4J3D A;  4WUD A;  1ZM3 A;  4PU9 A;  4JI8 E;  2BA0 G;  4JI2 E;  1ZXM A;  2C39 A;  2OI2 A;  4LOM A;  4OO1 E;  4MU1 A;  4LCG A;  1Y60 A;  4PRV A;  2PNL A;  3T1H I;  1HNW I;  1U2R A;  3OTO E;  3PS1 A;  3L7Z A;  1E3H A;  1OYS A;  2AE8 A;  1HNX I;  4JI6 E;  3J80 C;  1IBK E;  2ZBK B;  3CWV A;  4OX9 I;  1XMQ E;  2UXC E;  3B82 A;  4FW6 A;  3PS3 A;  4YHH E;  1E3P A;  4MDT A;  4X62 E;  1D6T A;  2GQ0 A;  5JEA E;  4DPT A;  2PNZ A;  3U1Y A;  1KVK A;  4LFC I;  4JI1 E;  2V34 A;  3U1K A;  4LF7 E;  1NHI A;  4WUC A;  5LMN I;  2BV3 A;  4FWH A;  1VI7 A;  5DNX A;  3GCM A;  4FW4 A;  1HR0 E;  1YH8 A;  2A2D A;  2IOP A;  4X66 E;  1Y4S A;  1Y6Z A;  5JEA F;  1WUU A;  2BR2 A;  1IBM I;  5K36 F;  3P3G A;  1KTV A;  4DR2 E;  1XMO I;  2CZ9 A;  3M85 G;  1HNZ E;  4LFC E;  3T1Y I;  1XNR I;  4DV4 E;  3PYE A;  1XHK A;  2F4V E;  1N34 I;  3P3E A;  4JI7 E;  4DR7 I;  4FN5 A;  2HK3 A;  3CDJ A;  3QT6 A;  3M7N D;  3PYG A;  2PO1 B;  2PO1 A;  1USV A;  1FJG E;  1B63 A;  4B3R I;  1XXE A;  1PKP A;  4DR5 E;  3M6A A;  1IBL E;  1ZM2 A;  3F0N A;  3LNU A;  2HFS A;  4DUY I;  5IT9 Q;  1N0U A;  4IZJ B;  1Z0B A;  4FW3 A;  5ELW A;  2BM1 A;  4GKJ E;  2AJ4 A;  4DPX A;  2PNM A;  4DXL A;  4LFA I;  1H73 A;  1USU A;  4IZK B;  5DRP A;  2PO2 A;  2PO2 B;  1R6L A;  2C38 A;  5A2Q Q;  1B62 A;  4LCF A;  3HJC A;  5JEA C;  1NHH A;  2CVE A;  4IFD F;  2IES A;  4IFD B;  3WU5 A;  2F1D A;  1Z0G A;  4DU7 A;  1Z0C A;  1A6F A;  3T1Y E;  1XNR E;  1MU5 A;  3T1H E;  4DR3 E;  3B8H A;  4HAC B;  1R6M A;  1IBM E;  4IFD C;  4IZJ D;  2VF3 A;  1MX0 A;  4UTG A;  3L7Z B;  3V2U C;  4USM A;  1Z0E A;  3K85 A;  4LF7 I;  4IFD A;  4LF5 E;  5IWA I;  4DV0 E;  3ZM7 A;  1OJ4 A;  4LFB E;  3LPS A;  4PRX A;  4OO1 A;  4YY3 E;  1KKH A;  4ED4 A;  4MU3 A;  3M85 D;  5C0X F;  1UDN A;  1HNX E;  4R1F A;  3QT7 A;  1FNM A;  4LF6 E;  1I94 E;  2UUA I;  4B3T I;  4IZJ A;  2GO4 A;  4JYA E;  1HNW E;  5LL6 R;  1HNZ I;  1Y4U A;  2PO0 B;  5JEA B;  2JEB B;  2VQF I;  4LPF A;  1NZ0 A;  2V2Q A;  4FWD A;  3WU4 A;  4IFD E;  5C0X A;  4JI2 I;  3DD6 A;  4JI3 E;  4U3B A;  5LMN E;  3PYF A;  4BA2 B;  3D4J A;  1OYP A;  4JI0 E;  3Q1Q A;  3B4T A;  2WW4 A;  4NXM I;  2UXB I;  1S16 A;  1QZR A;  2E5L E;  4N3O A;  4QNJ A;  4DV4 I;  2Z5B B;  5K36 B;  5C0X B;  4FW5 A;  2C39 B;  5LMU I;  1ZM4 A;  5LMU E;  4DV7 E;  5BR8 E;  4HAC A;  4B3M E;  3CDI A;  1Z5C A;  3P3C A;  4OZE A;  2VQE E;  3H1C A;  4URL A;  4DV2 E;  4ISA A;  2NN6 C;  2JE6 A;  5FLX C;  2NN6 B;  4OKG A;  3ZZU A;  4K0K I;  3QT8 A;  2IOQ A;  2O3Z A;  2GO3 A;  4DPU A;  1XNQ E;  4DV3 I;  4LF8 E;  4HXZ A;  2HHH I;  1S4E A;  2WNR B;  4DR6 E;  4GKJ I;  2VQF E;  2O1W A;  1Z5A A;  2BA1 G;  5K36 C;  1N34 E;  1J5E I;  5C0X D;  1IBL I;  4NBQ A;  2BM0 A;  1N32 I;  4IS9 A;  5GMD A;  2Z5C A;  4HYM A;  2C37 B;  1N32 E;  4DR6 I;  2R3V A;  2HK2 A;  4AIM A;  3JAM Q;  1ZXN A;  4P7A A;  4OO1 C;  2NN6 F;  2NN6 D;  2JE6 B;  4X65 I;  4OO1 F;  1NHJ A;  5GME A;  1Z0W A;  4USK A;  1PVG A;  5DNL A;  2HKJ A;  3Q6M A;  4Z7Y A;  4JG4 A;  4DR5 I;  4IZK A;  4DR1 I;  3PYD A;  1UDO A;  1N0V C;  1IBK I;  2DEI A;  4X66 I;  1RHY A;  2IER A;  3K1J A;  5K36 A;  4DR3 I;  1FJG I;  4FW7 A;  4X64 E;  2JT2 A;  4MYT A;  4KHP E;  4FW9 A;  2HKE A;  4OO1 D;  1UDS A;  1FWK A;  2F4V I; 
#chains in the Genus database with same CATH homology
 4LCF A;  1XXE A;  4U3D A;  4MQY A;  3P76 A;  3NZK A;  2IES A;  1YH8 A;  3P3G A;  3P3C A;  4OZE A;  4U3B A;  3PS2 A;  4FW3 A;  2IER A;  4ISA A;  1P42 A;  4IS9 A;  4J3D A;  2J65 A;  4FW6 A;  4OKG A;  3PS3 A;  4MDT A;  2VES A;  4FW7 A;  2JT2 A;  2O3Z A;  3U1Y A;  3P3E A;  3UHM A;  2GO4 A;  5DRP A;  4LCG A;  2GO3 A;  1YHC A;  4FW5 A;  5DRQ A;  4LCH A;  4FW4 A;  5DRR A;  5DRO A;  3PS1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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