3P3EA

Crystal structure of the pseudomonas aeruginosa lpxc/lpc-009 complex
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
297
structure length
297
Chain Sequence
b'MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYM'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
total genus 83
structure length 297
sequence length 297
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2010-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3p3eA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3p3eA02
5DROA 1YH8A 3P76A 3P3GA 3NZKA 4FW5A 4IS9A 4ISAA 2VESA 3U1YA 1YHCA 4LCFA 2IERA 4FW7A 4FW6A 3P3CA 4OKGA 5DRQA 2GO4A 2JT2A 2O3ZA 4J3DA 3UHMA 1P42A 3P3EA 2GO3A 4U3BA 4OZEA 4FW3A 4MQYA 2IESA 4FW4A 1XXEA 3PS1A 4MDTA 5DRRA 2J65A 3PS3A 4LCHA 5DRPA 3PS2A 4U3DA 4LCGA
chains in the Genus database with same CATH superfamily
2XEXA 2WW4A 4DV3I 4I3HA 4OO1F 2UUCI 1HNXE 3QT6A 1XNQI 2PO0B 3J7AM 4LF6I 4JI3E 3K1JA 2ZBKB 4USKA 4JV5E 4DPUA 3PYGA 1MU5A 4LFBI 2HK2A 4OO1D 1ZM4A 3B8HA 5IT9C 1Z59A 5GMDA 4LF8I 3J7AG 4IZKB 3PYDA 1HNZI 4DR5I 2V2ZA 1OYSA 1FJGI 1U2RA 1Y6ZA 2UXDI 2JE6A 1H74A 5DRQA 2NN6A 3LTOA 2UXBI 5C0XC 4J3DA 4K0KE 4DPWA 2C37A 2HKJA 4BA1B 2IESA 4DUYE 2UUAI 4IZJD 1XXEA 1XHKA 4B3RE 3PS3A 3GCMA 5JEAA 3QT7A 4OO1C 3B82A 4JG4A 1HR0I 1YH8A 3B4TA 1KIJA 3ZKBA 4JI4E 1USUA 4R1FA 2WNRA 4ISAA 1PIEA 4QNJA 2VQFE 4FN5A 1EI1A 4LF9E 1N34E 1FKAE 4GKJE 2O3ZA 2OI2A 5C0XE 2HHHE 4DU7A 4OZEA 2PNMA 1ZM3A 5DRRA 2WP8A 2C38A 1HNWE 4X65E 4DR3I 3V2UC 4YY3E 4LF5I 5IT9Q 3PYFA 4JI1I 5BR8E 4LFCI 4GKKE 3HJCA 3U1YA 4JI8I 4EMDA 1Y5YA 3M7NG 4JI2I 4OKGA 2PO2A 5C0XA 2C39A 1B62A 4LPFA 4NBQA 4AIMA 4DUZE 4FW4A 5IWAI 4X64I 3ZZTA 3DD6A 4XTJA 2HFSA 4P52A 2BR2A 2Z5CB 4MU0A 4OO1A 2PNZB 3LPSA 1R6MA 1IBLI 1Z0BA 1Z5AA 2X36A 1MX0A 4Z7CA 5LMUI 4DV5E 4DV6I 1XMQI 4B3ME 4LCFA 3P06A 1N0VC 3OTOI 2NN6C 4B3SE 4AIDA 4DR6I 3GONA 3H1CA 3CDIA 4DV7I 1USVA 4NXNI 4JI0E 4USMA 4IFDD 1NZ0A 1IBKI 1MG7A 4LOMA 2CGEA 2E5LE 1Z0CA 4JYAI 4PRXA 1R6LA 3ZM7A 2VQEE 1K47A 4DR1I 2UUBE 2ZITA 4JI5E 1BKNA 4AQYE 4LF6E 3JAMC 4YHHE 2UXCE 2NN6E 2DEIA 3UHMA 4HYMA 1N0UA 2Z5BB 4DV4I 5LMNI 4LFAE 1NHIA 4IFDC 3T1YE 1Y60A 4JI7I 1DARA 4FWDA 3CWVA 5JEAE 2PO1B 3WU6A 1RREA 1FWKA 4URLA 4MYUA 4DR5E 2JEBA 3P3GA 1B63A 1HNXI 4LF4E 1ZM2A 1UDSA 1S4EA 2IOQA 5K36B 4DR4E 2UXBE 5LL6R 1WUUA 4DV1E 4JI3I 4JV5I 4UTGA 4N3OA 2O1TA 2UU9E 2JEAA 2NPFA 2GS8A 3ZZUA 2J65A 2F4VE 2VF3A 1OJ4A 2ZM6E 3Q1QA 2JE6B 5DROA 2E1RA 4IS9A 1E3HA 2C37B 4FWHA 1UDQA 4Z7YA 4KHPI 5JEAB 4JI6E 4K0KI 4MU4A 1UDNA 3WU4A 2R3VA 1FNMA 4HACB 4DUYI 3V5RA 4DV2E 1IBME 3JAMQ 2Z5EA 4B3RI 1ELOA 3Q6MA 4IFDA 2LJPA 5K36F 3PS2A 4OO1E 1D6TA 4JI4I 4NXME 4MU3A 4OX9E 4BA2B 4ZVIA 3QT5A 2EFGA 1E3PA 2VQFI 1VISA 1N33E 3ZZ0A 1ZXMA 2O1VA 1YHCA 3U1KA 3J81C 4JI8E 3M85D 4LF7I 4LF9I 3P3CA 1N34I 4JI2E 2WP8B 4GKJI 2HHHI 5K36D 4DV0I 4X64E 1XMOE 4DR7E 1HNWI 4X65I 1J5EI 1EA6A 2O1UA 4DR2E 1PKPA 2R42A 4YY3I 5JEAF 1S16A 4B3TE 2X7IA 3WU3A 3P76A 5C0XB 3NZKA 1XNRE 4GKKI 4FW5A 1N36E 1KKHA 3T1HE 2DEJA 1NHJA 5A2QC 4FW6A 1QZRA 1I94E 2AE8A 4QNKA 4DR6E 1FI4A 1OYPA 2BA0G 3L7ZB 3P3EA 5FLXC 4DUZI 4HY1A 5JEAD 4X62E 1N32E 4IZJA 4U3DA 2BA1G 3PRYA 4DPYA 3K85A 4DV3E 4DV5I 4B3MI 3H4LA 2UUCE 1H7SA 4HXZA 4KQVA 2IERA 1XNQE 4B3SI 4AM3A 1UEKA 1KTVA 2IOPA 3J81Q 4X66I 4JI0I 5C0XF 2PO0A 4LFBE 4JI7E 4WUBA 4DPXA 2PNLA 4FW9A 4LF8E 2A2CA 5GMEA 1Y4UA 1HNZE 2V2QA 2VQEI 2UUBI 2VESA 3B78A 3J80C 1HK7A 5C0XD 4JI5I 2PO1A 4FW7A 4WUCA 1FJGE 5EL9A 4AQYI 4IZKA 4MU1A 1Z5BA 2UXDE 4YHHI 2UXCI 1Z0GA 2AJ4A 2J7KA 5A2QQ 5L3JA 1P42A 4LFAI 1ZXNA 5EKWA 5K36A 3F0NA 2UUAE 2JEBB 1Z0EA 3T1YI 5FLXQ 5DRPA 1FWLA 3KRNA 3PYEA 4BA1A 4WUDA 4IFDE 4LCGA 1Z5CA 2NN6B 1HR0E 3M6AA 3GMEA 4LF4I 2JEAB 4DXLA 2HFUA 3LNUA 4DR4I 4DV1I 4ED4A 1NHHA 4KHPE 2HKEA 3M7ND 2UU9I 1H72C 3PS1A 4P7AA 2F4VI 1Z0VA 4DU8A 5ELWA 2WNRB 2ZM6I 4RPFA 4DR3E 2Q2EB 4HACA 4LF5E 3HKMA 4JI1E 4LFCE 2V8PA 4LF7E 1A6FA 3CDJA 4BA2A 4JI6I 2GQ0A 1Z0WA 2C38B 3J80Q 2BV3A 4IFDB 4DV0E 2BA0D 3ZKDA 4DV2I 2NN6F 1IBMI 5IWAE 1UDOA 4M1KA 4MDTA 4LCHA 1J5EE 1KVKA 4FWGA 3K17A 2A2DA 4NXMI 4OX9I 3D4JA 1IBLE 2PO2B 1VI7A 5BR8I 1N33I 2BA1D 4UT4A 2C39B 2Z5CA 5LMUE 3QT8A 4DV6E 2NN6D 1XMQE 2PNZA 3WU5A 5FWKA 3OTOE 2GO4A 2JT2A 1ZM9A 1H7UA 1H73A 2BR2B 5DNLA 1Z0TA 3Q6NA 2GO3A 4DV7E 4U3BA 4OO1B 4MQYA 1XMOI 5K36C 4NXNE 3HULA 4DR7I 2BM0A 1IBKE 4DR2I 3L7ZA 4DPTA 4JYAE 4B3TI 2CVEA 2F1DA 2BM1A 2CG9A 4IFDF 1XNRI 1N36I 3M85G 3T1HI 4MYTA 1RR9A 4DR1E 1I94I 1PVGA 1OYRA 2V2VA 1RHYA 2HK3A 4GQUA 4IZJB 4PRVA 4X66E 2V34A 2CZ9A 4FW3A 4X62I 4PU9A 4DV4E 3GLLA 2O1WA 5LMNE 1N32I 5K36E 5JEAC 1Y4SA 2E5LI 5DNXA 2Z5BA
chains in the Genus database with same CATH topology
5DROA 1YH8A 3P76A 3P3GA 3NZKA 4FW5A 4IS9A 4ISAA 2VESA 3U1YA 1YHCA 4LCFA 2IERA 4FW7A 4FW6A 3P3CA 4OKGA 5DRQA 2GO4A 2JT2A 2O3ZA 4J3DA 3UHMA 1P42A 3P3EA 2GO3A 4U3BA 4OZEA 4FW3A 4MQYA 2IESA 4FW4A 1XXEA 3PS1A 4MDTA 5DRRA 2J65A 3PS3A 4LCHA 5DRPA 3PS2A 4U3DA 4LCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DRO A;  1YH8 A;  3P76 A;  3P3G A;  3NZK A;  4FW5 A;  4IS9 A;  4ISA A;  2VES A;  3U1Y A;  1YHC A;  4LCF A;  2IER A;  4FW7 A;  4FW6 A;  3P3C A;  4OKG A;  5DRQ A;  2GO4 A;  2JT2 A;  2O3Z A;  4J3D A;  3UHM A;  1P42 A;  3P3E A;  2GO3 A;  4U3B A;  4OZE A;  4FW3 A;  4MQY A;  2IES A;  4FW4 A;  1XXE A;  3PS1 A;  4MDT A;  5DRR A;  2J65 A;  3PS3 A;  4LCH A;  5DRP A;  3PS2 A;  4U3D A;  4LCG A; 
#chains in the Genus database with same CATH topology
 2XEX A;  2WW4 A;  4DV3 I;  4I3H A;  4OO1 F;  2UUC I;  1HNX E;  3QT6 A;  1XNQ I;  2PO0 B;  3J7A M;  4LF6 I;  4JI3 E;  3K1J A;  2ZBK B;  4USK A;  4JV5 E;  4DPU A;  3PYG A;  1MU5 A;  4LFB I;  2HK2 A;  4OO1 D;  1ZM4 A;  3B8H A;  5IT9 C;  1Z59 A;  5GMD A;  4LF8 I;  3J7A G;  4IZK B;  3PYD A;  1HNZ I;  4DR5 I;  2V2Z A;  1OYS A;  1FJG I;  1U2R A;  1Y6Z A;  2UXD I;  2JE6 A;  1H74 A;  5DRQ A;  2NN6 A;  3LTO A;  2UXB I;  5C0X C;  4J3D A;  4K0K E;  4DPW A;  2C37 A;  2HKJ A;  4BA1 B;  2IES A;  4DUY E;  2UUA I;  4IZJ D;  1XXE A;  1XHK A;  4B3R E;  3PS3 A;  3GCM A;  5JEA A;  3QT7 A;  4OO1 C;  3B82 A;  4JG4 A;  1HR0 I;  1YH8 A;  3B4T A;  1KIJ A;  3ZKB A;  4JI4 E;  1USU A;  4R1F A;  2WNR A;  4ISA A;  1PIE A;  4QNJ A;  2VQF E;  4FN5 A;  1EI1 A;  4LF9 E;  1N34 E;  1FKA E;  4GKJ E;  2O3Z A;  2OI2 A;  5C0X E;  2HHH E;  4DU7 A;  4OZE A;  2PNM A;  1ZM3 A;  5DRR A;  2WP8 A;  2C38 A;  1HNW E;  4X65 E;  4DR3 I;  3V2U C;  4YY3 E;  4LF5 I;  5IT9 Q;  3PYF A;  4JI1 I;  5BR8 E;  4LFC I;  4GKK E;  3HJC A;  3U1Y A;  4JI8 I;  4EMD A;  1Y5Y A;  3M7N G;  4JI2 I;  4OKG A;  2PO2 A;  5C0X A;  2C39 A;  1B62 A;  4LPF A;  4NBQ A;  4AIM A;  4DUZ E;  4FW4 A;  5IWA I;  4X64 I;  3ZZT A;  3DD6 A;  4XTJ A;  2HFS A;  4P52 A;  2BR2 A;  2Z5C B;  4MU0 A;  4OO1 A;  2PNZ B;  3LPS A;  1R6M A;  1IBL I;  1Z0B A;  1Z5A A;  2X36 A;  1MX0 A;  4Z7C A;  5LMU I;  4DV5 E;  4DV6 I;  1XMQ I;  4B3M E;  4LCF A;  3P06 A;  1N0V C;  3OTO I;  2NN6 C;  4B3S E;  4AID A;  4DR6 I;  3GON A;  3H1C A;  3CDI A;  4DV7 I;  1USV A;  4NXN I;  4JI0 E;  4USM A;  4IFD D;  1NZ0 A;  1IBK I;  1MG7 A;  4LOM A;  2CGE A;  2E5L E;  1Z0C A;  4JYA I;  4PRX A;  1R6L A;  3ZM7 A;  2VQE E;  1K47 A;  4DR1 I;  2UUB E;  2ZIT A;  4JI5 E;  1BKN A;  4AQY E;  4LF6 E;  3JAM C;  4YHH E;  2UXC E;  2NN6 E;  2DEI A;  3UHM A;  4HYM A;  1N0U A;  2Z5B B;  4DV4 I;  5LMN I;  4LFA E;  1NHI A;  4IFD C;  3T1Y E;  1Y60 A;  4JI7 I;  1DAR A;  4FWD A;  3CWV A;  5JEA E;  2PO1 B;  3WU6 A;  1RRE A;  1FWK A;  4URL A;  4MYU A;  4DR5 E;  2JEB A;  3P3G A;  1B63 A;  1HNX I;  4LF4 E;  1ZM2 A;  1UDS A;  1S4E A;  2IOQ A;  5K36 B;  4DR4 E;  2UXB E;  5LL6 R;  1WUU A;  4DV1 E;  4JI3 I;  4JV5 I;  4UTG A;  4N3O A;  2O1T A;  2UU9 E;  2JEA A;  2NPF A;  2GS8 A;  3ZZU A;  2J65 A;  2F4V E;  2VF3 A;  1OJ4 A;  2ZM6 E;  3Q1Q A;  2JE6 B;  5DRO A;  2E1R A;  4IS9 A;  1E3H A;  2C37 B;  4FWH A;  1UDQ A;  4Z7Y A;  4KHP I;  5JEA B;  4JI6 E;  4K0K I;  4MU4 A;  1UDN A;  3WU4 A;  2R3V A;  1FNM A;  4HAC B;  4DUY I;  3V5R A;  4DV2 E;  1IBM E;  3JAM Q;  2Z5E A;  4B3R I;  1ELO A;  3Q6M A;  4IFD A;  2LJP A;  5K36 F;  3PS2 A;  4OO1 E;  1D6T A;  4JI4 I;  4NXM E;  4MU3 A;  4OX9 E;  4BA2 B;  4ZVI A;  3QT5 A;  2EFG A;  1E3P A;  2VQF I;  1VIS A;  1N33 E;  3ZZ0 A;  1ZXM A;  2O1V A;  1YHC A;  3U1K A;  3J81 C;  4JI8 E;  3M85 D;  4LF7 I;  4LF9 I;  3P3C A;  1N34 I;  4JI2 E;  2WP8 B;  4GKJ I;  2HHH I;  5K36 D;  4DV0 I;  4X64 E;  1XMO E;  4DR7 E;  1HNW I;  4X65 I;  1J5E I;  1EA6 A;  2O1U A;  4DR2 E;  1PKP A;  2R42 A;  4YY3 I;  5JEA F;  1S16 A;  4B3T E;  2X7I A;  3WU3 A;  3P76 A;  5C0X B;  3NZK A;  1XNR E;  4GKK I;  4FW5 A;  1N36 E;  1KKH A;  3T1H E;  2DEJ A;  1NHJ A;  5A2Q C;  4FW6 A;  1QZR A;  1I94 E;  2AE8 A;  4QNK A;  4DR6 E;  1FI4 A;  1OYP A;  2BA0 G;  3L7Z B;  3P3E A;  5FLX C;  4DUZ I;  4HY1 A;  5JEA D;  4X62 E;  1N32 E;  4IZJ A;  4U3D A;  2BA1 G;  3PRY A;  4DPY A;  3K85 A;  4DV3 E;  4DV5 I;  4B3M I;  3H4L A;  2UUC E;  1H7S A;  4HXZ A;  4KQV A;  2IER A;  1XNQ E;  4B3S I;  4AM3 A;  1UEK A;  1KTV A;  2IOP A;  3J81 Q;  4X66 I;  4JI0 I;  5C0X F;  2PO0 A;  4LFB E;  4JI7 E;  4WUB A;  4DPX A;  2PNL A;  4FW9 A;  4LF8 E;  2A2C A;  5GME A;  1Y4U A;  1HNZ E;  2V2Q A;  2VQE I;  2UUB I;  2VES A;  3B78 A;  3J80 C;  1HK7 A;  5C0X D;  4JI5 I;  2PO1 A;  4FW7 A;  4WUC A;  1FJG E;  5EL9 A;  4AQY I;  4IZK A;  4MU1 A;  1Z5B A;  2UXD E;  4YHH I;  2UXC I;  1Z0G A;  2AJ4 A;  2J7K A;  5A2Q Q;  5L3J A;  1P42 A;  4LFA I;  1ZXN A;  5EKW A;  5K36 A;  3F0N A;  2UUA E;  2JEB B;  1Z0E A;  3T1Y I;  5FLX Q;  5DRP A;  1FWL A;  3KRN A;  3PYE A;  4BA1 A;  4WUD A;  4IFD E;  4LCG A;  1Z5C A;  2NN6 B;  1HR0 E;  3M6A A;  3GME A;  4LF4 I;  2JEA B;  4DXL A;  2HFU A;  3LNU A;  4DR4 I;  4DV1 I;  4ED4 A;  1NHH A;  4KHP E;  2HKE A;  3M7N D;  2UU9 I;  1H72 C;  3PS1 A;  4P7A A;  2F4V I;  1Z0V A;  4DU8 A;  5ELW A;  2WNR B;  2ZM6 I;  4RPF A;  4DR3 E;  2Q2E B;  4HAC A;  4LF5 E;  3HKM A;  4JI1 E;  4LFC E;  2V8P A;  4LF7 E;  1A6F A;  3CDJ A;  4BA2 A;  4JI6 I;  2GQ0 A;  1Z0W A;  2C38 B;  3J80 Q;  2BV3 A;  4IFD B;  4DV0 E;  2BA0 D;  3ZKD A;  4DV2 I;  2NN6 F;  1IBM I;  5IWA E;  1UDO A;  4M1K A;  4MDT A;  4LCH A;  1J5E E;  1KVK A;  4FWG A;  3K17 A;  2A2D A;  4NXM I;  4OX9 I;  3D4J A;  1IBL E;  2PO2 B;  1VI7 A;  5BR8 I;  1N33 I;  2BA1 D;  4UT4 A;  2C39 B;  2Z5C A;  5LMU E;  3QT8 A;  4DV6 E;  2NN6 D;  1XMQ E;  2PNZ A;  3WU5 A;  5FWK A;  3OTO E;  2GO4 A;  2JT2 A;  1ZM9 A;  1H7U A;  1H73 A;  2BR2 B;  5DNL A;  1Z0T A;  3Q6N A;  2GO3 A;  4DV7 E;  4U3B A;  4OO1 B;  4MQY A;  1XMO I;  5K36 C;  4NXN E;  3HUL A;  4DR7 I;  2BM0 A;  1IBK E;  4DR2 I;  3L7Z A;  4DPT A;  4JYA E;  4B3T I;  2CVE A;  2F1D A;  2BM1 A;  2CG9 A;  4IFD F;  1XNR I;  1N36 I;  3M85 G;  3T1H I;  4MYT A;  1RR9 A;  4DR1 E;  1I94 I;  1PVG A;  1OYR A;  2V2V A;  1RHY A;  2HK3 A;  4GQU A;  4IZJ B;  4PRV A;  4X66 E;  2V34 A;  2CZ9 A;  4FW3 A;  4X62 I;  4PU9 A;  4DV4 E;  3GLL A;  2O1W A;  5LMN E;  1N32 I;  5K36 E;  5JEA C;  1Y4S A;  2E5L I;  5DNX A;  2Z5B A; 
#chains in the Genus database with same CATH homology
 5DRO A;  1YH8 A;  3P76 A;  3P3G A;  3NZK A;  4FW5 A;  4IS9 A;  4ISA A;  2VES A;  3U1Y A;  1YHC A;  4LCF A;  2IER A;  4FW7 A;  4FW6 A;  3P3C A;  4OKG A;  5DRQ A;  2GO4 A;  2JT2 A;  2O3Z A;  4J3D A;  3UHM A;  1P42 A;  3P3E A;  2GO3 A;  4U3B A;  4OZE A;  4FW3 A;  4MQY A;  2IES A;  4FW4 A;  1XXE A;  3PS1 A;  4MDT A;  5DRR A;  2J65 A;  3PS3 A;  4LCH A;  5DRP A;  3PS2 A;  4U3D A;  4LCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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