3P3EA

Crystal structure of the pseudomonas aeruginosa lpxc/lpc-009 complex
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
297
structure length
297
Chain Sequence
b'MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYM'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
molecule tags Hydrolase
source organism Pseudomonas aeruginosa
publication title Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
pubmed doi rcsb
total genus 83
structure length 297
sequence length 297
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2010-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3p3eA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3p3eA02
2IESA 4MQYA 1YHCA 4OKGA 3P3GA 4FW6A 4IS9A 3P76A 4U3DA 4FW4A 5DROA 4LCHA 4FW7A 3NZKA 1YH8A 4MDTA 2GO3A 5DRRA 4OZEA 3U1YA 4FW5A 3P3EA 4LCGA 2JT2A 2IERA 3PS3A 4FW3A 4LCFA 2VESA 2O3ZA 3UHMA 5DRQA 4U3BA 3P3CA 2J65A 1P42A 5DRPA 1XXEA 3PS2A 4ISAA 3PS1A 2GO4A 4J3DA
chains in the Genus database with same CATH superfamily
1Y4UA 3B8HA 3QT6A 1NHJA 4MU0A 4FN5A 4OO1B 3LNUA 2GO3A 5BR8I 4DR7I 4JI8E 4B3SE 2UUCI 1E3HA 2BV3A 4JI1I 4X65I 4LF6E 2UUBE 4BA1B 4GKKI 4FW9A 5DNLA 5K36F 4U3BA 2NN6E 3OTOE 3GLLA 3B82A 3V2UC 2E5LE 1BKNA 1HNXI 4IZKA 4R1FA 1VISA 2E1RA 3DD6A 4LFAE 2WP8B 2V2VA 5EL9A 2NN6B 3B78A 5C0XD 4IS9A 1N32E 4LF4I 3QT8A 1OYSA 4UT4A 4MDTA 1Z0EA 1HNXE 2IERA 4DV7E 2UUBI 1ZM2A 4LF6I 4DR6I 2BM0A 3UHMA 4LF5E 1HR0I 4KHPI 2PNLA 1XNQE 4GKJI 3M7ND 2O1WA 4IZJB 4JYAI 2PNZB 4LPFA 4DXLA 2PO1B 4USMA 4JI4I 2VQEE 2HK3A 3WU5A 1QZRA 4JI5E 3ZZ0A 1MU5A 4K0KI 1XMOE 2JEBA 3PS3A 2R42A 2UXDE 5GMDA 4ZVIA 5K36A 3CDJA 3L7ZB 5JEAC 2EFGA 1IBLE 2A2DA 4LOMA 4B3SI 4DR7E 2PO2B 1FJGE 4J3DA 4LF9E 4QNKA 2V34A 2CGEA 4Z7CA 1HK7A 4DV3I 3LPSA 1NZ0A 5C0XC 4DV4I 3Q1QA 4JI5I 1RR9A 4FW5A 5JEAE 4B3MI 3PYGA 2LJPA 4X66I 2HHHE 4JI0E 4JI2E 1U2RA 4DR1E 1N36I 4DR2E 3J81C 5A2QQ 3ZZTA 2ZITA 4DPWA 4DV5E 4JG4A 1IBKI 3L7ZA 5C0XE 4JV5I 1J5EI 1FNMA 4DR6E 2JEBB 1H74A 5IWAI 1OYRA 2R3VA 1PVGA 4M1KA 4JI3E 4JI6I 4FWGA 4OZEA 1EA6A 2C39B 1IBKE 2BA1G 2NN6F 3P3EA 2PO1A 2GS8A 4URLA 1E3PA 4HYMA 1OJ4A 1USUA 2PNZA 1DARA 4WUCA 4B3RI 4DV0E 5ELWA 5LMNI 1XMQE 1P42A 4N3OA 4LFAI 1WUUA 4AM3A 1HNZI 3PYFA 4GKKE 4DV3E 5LL6R 1IBME 2DEIA 1KTVA 4LF8E 2O1VA 1FJGI 4JI8I 3K1JA 3F0NA 4IZJD 4DV5I 4DU8A 2UU9I 4LCFA 1FWLA 1VI7A 1UDNA 4Z7YA 4DR1I 2J65A 1PIEA 4DV6I 1Z0TA 5C0XF 3ZZUA 1Z5BA 1YHCA 2UXCE 2BA0G 1HNWE 1MX0A 4AIMA 2BM1A 4LFBE 2C37B 3QT7A 4ED4A 4OO1A 2F1DA 2JE6B 4OO1F 5L3JA 2CZ9A 3HJCA 1Z5CA 1IBMI 5IT9Q 1H72C 2PO0B 4LFBI 1EI1A 1ZM4A 5DRPA 4DR3I 3PS2A 3H4LA 4MU4A 4K0KE 1XNRI 2IESA 1S4EA 2XEXA 4LFCE 5FLXQ 4DV0I 1S16A 2HFSA 4DPUA 4YY3E 5A2QC 1H7UA 1UDQA 2Z5CB 4JYAE 4DV2E 3K17A 2UU9E 2ZM6I 1Z5AA 4AIDA 1N34I 3OTOI 3PRYA 4KHPE 1HR0E 4LF5I 4LF8I 5IWAE 4P7AA 3J7AM 4MYTA 4MYUA 5JEAF 4USKA 4HACA 3J80C 3Q6MA 3T1YE 2UUCE 1J5EE 4JV5E 4YHHI 4NXME 4WUDA 1RHYA 4DPXA 4FW4A 4LF4E 2HK2A 1N36E 2JE6A 4JI2I 4YY3I 2JEAA 2UXBI 2C37A 3GONA 2BR2A 1NHHA 4DUYI 2AJ4A 5LMUI 1XNRE 2IOQA 2Z5EA 5JEAA 1N33E 1FKAE 4NBQA 2IOPA 3V5RA 1H73A 2WNRB 1Z0BA 4P52A 4MU1A 4LF9I 4XTJA 4LF7I 5DROA 1KVKA 4DR2I 1Z0VA 1D6TA 1YH8A 5DRRA 4RPFA 4OX9E 5K36E 3U1YA 5C0XB 5EKWA 3T1HE 4HXZA 3M85G 4X66E 1Z0WA 4DV6E 4PU9A 4B3ME 3H1CA 2UUAE 1ZXMA 2C38A 4NXNE 2X7IA 3P3CA 1Z59A 1Y4SA 3GCMA 4UTGA 2VQEI 4JI4E 2UXBE 1Y6ZA 3ZKDA 4HY1A 2V2ZA 1KKHA 2GQ0A 3JAMC 1R6LA 4LF7E 3PYDA 5K36C 4FW6A 2X36A 1N0UA 4DU7A 4LCHA 1R6MA 1RREA 1UDOA 2V2QA 2C39A 4GQUA 3J81Q 4MU3A 2UXDI 5K36D 5FWKA 4FW3A 1N34E 1XMOI 2ZM6E 2CVEA 5LMUE 4DUZE 4DV1E 2NN6D 3CDIA 5LMNE 3K85A 2VQFE 2GO4A 4JI7E 4AQYI 2AE8A 4DPYA 4LFCI 4YHHE 2Z5BA 4DUZI 2F4VE 3QT5A 3J7AG 4JI6E 3NZKA 4JI3I 3D4JA 3WU6A 1A6FA 2ZBKB 2JT2A 4DV7I 2Z5BB 1Y60A 3GMEA 4X62E 1I94E 2WW4A 2PO2A 1ZM3A 1N32I 3HKMA 1XXEA 3M6AA 2O1UA 3PS1A 2PNMA 4DR4E 1ZM9A 2HKEA 5K36B 4MQYA 1Z0CA 3P3GA 4DR5E 4FW7A 4QNJA 5GMEA 1NHIA 4OX9I 4X65E 1MG7A 1UEKA 4JI1E 2O3ZA 2V8PA 4OO1D 4IZJA 2DEJA 1IBLI 1PKPA 1N0VC 2OI2A 3M85D 4B3TE 4I3HA 2C38B 4IFDC 1HNWI 2J7KA 1N33I 4WUBA 1KIJA 3ZKBA 2F4VI 5IT9C 5C0XA 3WU4A 4DUYE 1OYPA 4AQYE 1H7SA 2VQFI 4DR4I 3LTOA 3JAMQ 4IFDF 2BA1D 3HULA 4DV1I 2NN6A 4NXMI 4IFDD 1FWKA 4X64I 5FLXC 4X62I 1B63A 2WP8A 1I94I 4GKJE 4IFDE 1XNQI 2WNRA 3WU3A 2BA0D 4IZKB 4ISAA 3T1YI 4OO1C 1Y5YA 5JEAB 4BA1A 1XHKA 4PRXA 4FWHA 5DNXA 1HNZE 3KRNA 4U3DA 3U1KA 1USVA 1Z0GA 4X64E 2BR2B 5JEAD 4DV2I 1B62A 2JEAB 3J80Q 1XMQI 2NPFA 4JI7I 3M7NG 3CWVA 2VESA 4B3RE 2VF3A 5DRQA 4OO1E 2UUAI 4FWDA 1UDSA 4HACB 4DV4E 2E5LI 4DR3E 2Q2EB 3PYEA 4B3TI 4BA2B 2O1TA 4OKGA 3P76A 1K47A 2HKJA 4DPTA 5BR8E 1ZXNA 2Z5CA 4IFDA 4IFDB 1ELOA 2HFUA 4LCGA 3Q6NA 1FI4A 3B4TA 3P06A 3ZM7A 4JI0I 2HHHI 4BA2A 2UXCI 4NXNI 4EMDA 4DR5I 4PRVA 2A2CA 2PO0A 2CG9A 2NN6C 4KQVA 3T1HI
chains in the Genus database with same CATH topology
2IESA 4MQYA 1YHCA 4OKGA 3P3GA 4FW6A 4IS9A 3P76A 4U3DA 4FW4A 5DROA 4LCHA 4FW7A 3NZKA 1YH8A 4MDTA 2GO3A 5DRRA 4OZEA 3U1YA 4FW5A 3P3EA 4LCGA 2JT2A 2IERA 3PS3A 4FW3A 4LCFA 2VESA 2O3ZA 3UHMA 5DRQA 4U3BA 3P3CA 2J65A 1P42A 5DRPA 1XXEA 3PS2A 4ISAA 3PS1A 2GO4A 4J3DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IES A;  4MQY A;  1YHC A;  4OKG A;  3P3G A;  4FW6 A;  4IS9 A;  3P76 A;  4U3D A;  4FW4 A;  5DRO A;  4LCH A;  4FW7 A;  3NZK A;  1YH8 A;  4MDT A;  2GO3 A;  5DRR A;  4OZE A;  3U1Y A;  4FW5 A;  3P3E A;  4LCG A;  2JT2 A;  2IER A;  3PS3 A;  4FW3 A;  4LCF A;  2VES A;  2O3Z A;  3UHM A;  5DRQ A;  4U3B A;  3P3C A;  2J65 A;  1P42 A;  5DRP A;  1XXE A;  3PS2 A;  4ISA A;  3PS1 A;  2GO4 A;  4J3D A; 
#chains in the Genus database with same CATH topology
 1Y4U A;  3B8H A;  3QT6 A;  1NHJ A;  4MU0 A;  4FN5 A;  4OO1 B;  3LNU A;  2GO3 A;  5BR8 I;  4DR7 I;  4JI8 E;  4B3S E;  2UUC I;  1E3H A;  2BV3 A;  4JI1 I;  4X65 I;  4LF6 E;  2UUB E;  4BA1 B;  4GKK I;  4FW9 A;  5DNL A;  5K36 F;  4U3B A;  2NN6 E;  3OTO E;  3GLL A;  3B82 A;  3V2U C;  2E5L E;  1BKN A;  1HNX I;  4IZK A;  4R1F A;  1VIS A;  2E1R A;  3DD6 A;  4LFA E;  2WP8 B;  2V2V A;  5EL9 A;  2NN6 B;  3B78 A;  5C0X D;  4IS9 A;  1N32 E;  4LF4 I;  3QT8 A;  1OYS A;  4UT4 A;  4MDT A;  1Z0E A;  1HNX E;  2IER A;  4DV7 E;  2UUB I;  1ZM2 A;  4LF6 I;  4DR6 I;  2BM0 A;  3UHM A;  4LF5 E;  1HR0 I;  4KHP I;  2PNL A;  1XNQ E;  4GKJ I;  3M7N D;  2O1W A;  4IZJ B;  4JYA I;  2PNZ B;  4LPF A;  4DXL A;  2PO1 B;  4USM A;  4JI4 I;  2VQE E;  2HK3 A;  3WU5 A;  1QZR A;  4JI5 E;  3ZZ0 A;  1MU5 A;  4K0K I;  1XMO E;  2JEB A;  3PS3 A;  2R42 A;  2UXD E;  5GMD A;  4ZVI A;  5K36 A;  3CDJ A;  3L7Z B;  5JEA C;  2EFG A;  1IBL E;  2A2D A;  4LOM A;  4B3S I;  4DR7 E;  2PO2 B;  1FJG E;  4J3D A;  4LF9 E;  4QNK A;  2V34 A;  2CGE A;  4Z7C A;  1HK7 A;  4DV3 I;  3LPS A;  1NZ0 A;  5C0X C;  4DV4 I;  3Q1Q A;  4JI5 I;  1RR9 A;  4FW5 A;  5JEA E;  4B3M I;  3PYG A;  2LJP A;  4X66 I;  2HHH E;  4JI0 E;  4JI2 E;  1U2R A;  4DR1 E;  1N36 I;  4DR2 E;  3J81 C;  5A2Q Q;  3ZZT A;  2ZIT A;  4DPW A;  4DV5 E;  4JG4 A;  1IBK I;  3L7Z A;  5C0X E;  4JV5 I;  1J5E I;  1FNM A;  4DR6 E;  2JEB B;  1H74 A;  5IWA I;  1OYR A;  2R3V A;  1PVG A;  4M1K A;  4JI3 E;  4JI6 I;  4FWG A;  4OZE A;  1EA6 A;  2C39 B;  1IBK E;  2BA1 G;  2NN6 F;  3P3E A;  2PO1 A;  2GS8 A;  4URL A;  1E3P A;  4HYM A;  1OJ4 A;  1USU A;  2PNZ A;  1DAR A;  4WUC A;  4B3R I;  4DV0 E;  5ELW A;  5LMN I;  1XMQ E;  1P42 A;  4N3O A;  4LFA I;  1WUU A;  4AM3 A;  1HNZ I;  3PYF A;  4GKK E;  4DV3 E;  5LL6 R;  1IBM E;  2DEI A;  1KTV A;  4LF8 E;  2O1V A;  1FJG I;  4JI8 I;  3K1J A;  3F0N A;  4IZJ D;  4DV5 I;  4DU8 A;  2UU9 I;  4LCF A;  1FWL A;  1VI7 A;  1UDN A;  4Z7Y A;  4DR1 I;  2J65 A;  1PIE A;  4DV6 I;  1Z0T A;  5C0X F;  3ZZU A;  1Z5B A;  1YHC A;  2UXC E;  2BA0 G;  1HNW E;  1MX0 A;  4AIM A;  2BM1 A;  4LFB E;  2C37 B;  3QT7 A;  4ED4 A;  4OO1 A;  2F1D A;  2JE6 B;  4OO1 F;  5L3J A;  2CZ9 A;  3HJC A;  1Z5C A;  1IBM I;  5IT9 Q;  1H72 C;  2PO0 B;  4LFB I;  1EI1 A;  1ZM4 A;  5DRP A;  4DR3 I;  3PS2 A;  3H4L A;  4MU4 A;  4K0K E;  1XNR I;  2IES A;  1S4E A;  2XEX A;  4LFC E;  5FLX Q;  4DV0 I;  1S16 A;  2HFS A;  4DPU A;  4YY3 E;  5A2Q C;  1H7U A;  1UDQ A;  2Z5C B;  4JYA E;  4DV2 E;  3K17 A;  2UU9 E;  2ZM6 I;  1Z5A A;  4AID A;  1N34 I;  3OTO I;  3PRY A;  4KHP E;  1HR0 E;  4LF5 I;  4LF8 I;  5IWA E;  4P7A A;  3J7A M;  4MYT A;  4MYU A;  5JEA F;  4USK A;  4HAC A;  3J80 C;  3Q6M A;  3T1Y E;  2UUC E;  1J5E E;  4JV5 E;  4YHH I;  4NXM E;  4WUD A;  1RHY A;  4DPX A;  4FW4 A;  4LF4 E;  2HK2 A;  1N36 E;  2JE6 A;  4JI2 I;  4YY3 I;  2JEA A;  2UXB I;  2C37 A;  3GON A;  2BR2 A;  1NHH A;  4DUY I;  2AJ4 A;  5LMU I;  1XNR E;  2IOQ A;  2Z5E A;  5JEA A;  1N33 E;  1FKA E;  4NBQ A;  2IOP A;  3V5R A;  1H73 A;  2WNR B;  1Z0B A;  4P52 A;  4MU1 A;  4LF9 I;  4XTJ A;  4LF7 I;  5DRO A;  1KVK A;  4DR2 I;  1Z0V A;  1D6T A;  1YH8 A;  5DRR A;  4RPF A;  4OX9 E;  5K36 E;  3U1Y A;  5C0X B;  5EKW A;  3T1H E;  4HXZ A;  3M85 G;  4X66 E;  1Z0W A;  4DV6 E;  4PU9 A;  4B3M E;  3H1C A;  2UUA E;  1ZXM A;  2C38 A;  4NXN E;  2X7I A;  3P3C A;  1Z59 A;  1Y4S A;  3GCM A;  4UTG A;  2VQE I;  4JI4 E;  2UXB E;  1Y6Z A;  3ZKD A;  4HY1 A;  2V2Z A;  1KKH A;  2GQ0 A;  3JAM C;  1R6L A;  4LF7 E;  3PYD A;  5K36 C;  4FW6 A;  2X36 A;  1N0U A;  4DU7 A;  4LCH A;  1R6M A;  1RRE A;  1UDO A;  2V2Q A;  2C39 A;  4GQU A;  3J81 Q;  4MU3 A;  2UXD I;  5K36 D;  5FWK A;  4FW3 A;  1N34 E;  1XMO I;  2ZM6 E;  2CVE A;  5LMU E;  4DUZ E;  4DV1 E;  2NN6 D;  3CDI A;  5LMN E;  3K85 A;  2VQF E;  2GO4 A;  4JI7 E;  4AQY I;  2AE8 A;  4DPY A;  4LFC I;  4YHH E;  2Z5B A;  4DUZ I;  2F4V E;  3QT5 A;  3J7A G;  4JI6 E;  3NZK A;  4JI3 I;  3D4J A;  3WU6 A;  1A6F A;  2ZBK B;  2JT2 A;  4DV7 I;  2Z5B B;  1Y60 A;  3GME A;  4X62 E;  1I94 E;  2WW4 A;  2PO2 A;  1ZM3 A;  1N32 I;  3HKM A;  1XXE A;  3M6A A;  2O1U A;  3PS1 A;  2PNM A;  4DR4 E;  1ZM9 A;  2HKE A;  5K36 B;  4MQY A;  1Z0C A;  3P3G A;  4DR5 E;  4FW7 A;  4QNJ A;  5GME A;  1NHI A;  4OX9 I;  4X65 E;  1MG7 A;  1UEK A;  4JI1 E;  2O3Z A;  2V8P A;  4OO1 D;  4IZJ A;  2DEJ A;  1IBL I;  1PKP A;  1N0V C;  2OI2 A;  3M85 D;  4B3T E;  4I3H A;  2C38 B;  4IFD C;  1HNW I;  2J7K A;  1N33 I;  4WUB A;  1KIJ A;  3ZKB A;  2F4V I;  5IT9 C;  5C0X A;  3WU4 A;  4DUY E;  1OYP A;  4AQY E;  1H7S A;  2VQF I;  4DR4 I;  3LTO A;  3JAM Q;  4IFD F;  2BA1 D;  3HUL A;  4DV1 I;  2NN6 A;  4NXM I;  4IFD D;  1FWK A;  4X64 I;  5FLX C;  4X62 I;  1B63 A;  2WP8 A;  1I94 I;  4GKJ E;  4IFD E;  1XNQ I;  2WNR A;  3WU3 A;  2BA0 D;  4IZK B;  4ISA A;  3T1Y I;  4OO1 C;  1Y5Y A;  5JEA B;  4BA1 A;  1XHK A;  4PRX A;  4FWH A;  5DNX A;  1HNZ E;  3KRN A;  4U3D A;  3U1K A;  1USV A;  1Z0G A;  4X64 E;  2BR2 B;  5JEA D;  4DV2 I;  1B62 A;  2JEA B;  3J80 Q;  1XMQ I;  2NPF A;  4JI7 I;  3M7N G;  3CWV A;  2VES A;  4B3R E;  2VF3 A;  5DRQ A;  4OO1 E;  2UUA I;  4FWD A;  1UDS A;  4HAC B;  4DV4 E;  2E5L I;  4DR3 E;  2Q2E B;  3PYE A;  4B3T I;  4BA2 B;  2O1T A;  4OKG A;  3P76 A;  1K47 A;  2HKJ A;  4DPT A;  5BR8 E;  1ZXN A;  2Z5C A;  4IFD A;  4IFD B;  1ELO A;  2HFU A;  4LCG A;  3Q6N A;  1FI4 A;  3B4T A;  3P06 A;  3ZM7 A;  4JI0 I;  2HHH I;  4BA2 A;  2UXC I;  4NXN I;  4EMD A;  4DR5 I;  4PRV A;  2A2C A;  2PO0 A;  2CG9 A;  2NN6 C;  4KQV A;  3T1H I; 
#chains in the Genus database with same CATH homology
 2IES A;  4MQY A;  1YHC A;  4OKG A;  3P3G A;  4FW6 A;  4IS9 A;  3P76 A;  4U3D A;  4FW4 A;  5DRO A;  4LCH A;  4FW7 A;  3NZK A;  1YH8 A;  4MDT A;  2GO3 A;  5DRR A;  4OZE A;  3U1Y A;  4FW5 A;  3P3E A;  4LCG A;  2JT2 A;  2IER A;  3PS3 A;  4FW3 A;  4LCF A;  2VES A;  2O3Z A;  3UHM A;  5DRQ A;  4U3B A;  3P3C A;  2J65 A;  1P42 A;  5DRP A;  1XXE A;  3PS2 A;  4ISA A;  3PS1 A;  2GO4 A;  4J3D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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