3PKAA

M. tuberculosis metap with bengamide analog y02, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkaA01
1WL9A 2P98A 2EA4A 5E5BA 2BWYA 1W7VA 1JAWA 2Q93A 1O0XA 3IU9A 2NQ7A 2V6CA 3FM3A 2GZ5A 3BIQA 4U71A 5D6FA 5CDEA 5FCHA 1C23A 1W2MA 2BWWA 3D27A 2BWTA 2Q96A 2P9AA 4IKRA 1QXZA 1XGNA 2BHCA 2OAZA 3PKEA 2EVCA 1WLRA 3PKDA 4IKSA 2EVOA 1MATA 1XGSA 1C21A 4IF7A 4ZWOA 3CTZA 1KQ0A 4OOKA 4IDYA 2P99A 3MR1A 1QXWA 3MX6A 1R5HA 2GG7A 1C22A 1YW7A 4U6CA 2BHBA 4FO7A 2GGBA 4QR8A 2EVMA 3MATA 1WY2A 2OKNA 5D6EA 4Z7MA 2BHDA 3PKBA 1N51A 4IKUA 3Q6DA 2V3XA 1XGOA 2B3HA 3L24A 1QZYA 2BWUA 4U6ZA 2IW2A 4A6WA 3PKCA 1KP0A 4PNCA 4R60A 4FUKA 1WKMA 1YJ3A 2GA2A 2GGCA 4U76A 5CNXA 4U6WA 2Q95A 4FLIA 2NQ6A 4U6EA 4U73A 4FLJA 3TAVA 1WL6A 2GU5A 4S2TP 1CHMA 5CDVA 2GTXA 2Q94A 4U1BA 3IG4A 2GU6A 2GG3A 3S6BA 4S01A 2BHAA 4MATA 4U75A 2BB7A 4IECA 3RORA 2GG8A 2BN7A 1WN1A 2GG0A 2BWSA 3FMQA 4RZYA 4FLLA 4U70A 2HOWA 2GU7A 5CE6A 2DFIA 5CIKA 4ZWPA 4B28A 3CB6A 4A6VA 4S2RP 5CLSA 4IPAA 1R58A 3IU7A 3CB5A 1KQ9A 5JFRA 4EGEA 1BOAA 2ZSGA 1BN5A 1WBQA 1XGMA 1XNZA 3BIPA 3RVAA 4KM3A 2B3LA 1YW9A 3PKAA 1YVMA 2V3ZA 5CDLA 2GG5A 2ADUA 2MATA 4JUQA 2B3KA 4FLKA 4IKTA 2GU4A 3BITA 2Q8KA 1Y1NA 5JI6A 4PV4A 4RZZA 2BH3A 4FKCA 2Q92A 1M35A 2GG9A 5FCFA 4FO8A 4U69A 4S00A 4IU6A 1B59A 2EA2A 5JHUA 2G6PA 1PV9A 4HXXA 3FMRA 1YW8A 1A16A 1C24A 1QXYA 2GG2A 4ZNGA 4ZWUA 1C27A 3IU8A 3TB5A 1R5GA 2BWVA 3L7GA 4U6JA 2V3YA 1B6AA 4RGZ1 2BWXA
chains in the Genus database with same CATH superfamily
1WL9A 2P98A 2EA4A 5E5BA 2BWYA 1W7VA 1JAWA 2Q93A 1O0XA 3IU9A 2NQ7A 2V6CA 3FM3A 2GZ5A 3BIQA 4U71A 5D6FA 5CDEA 5FCHA 1C23A 1W2MA 2BWWA 3D27A 2BWTA 2Q96A 2P9AA 4IKRA 1QXZA 1XGNA 2BHCA 2OAZA 3PKEA 2EVCA 1WLRA 3PKDA 4IKSA 2EVOA 1MATA 1XGSA 1C21A 4IF7A 4ZWOA 3CTZA 1KQ0A 4OOKA 4IDYA 2P99A 3MR1A 1QXWA 3MX6A 1R5HA 2GG7A 1C22A 1YW7A 4U6CA 2BHBA 4FO7A 2GGBA 4QR8A 2EVMA 3MATA 1WY2A 2OKNA 5D6EA 4Z7MA 2BHDA 3PKBA 1N51A 4IKUA 3Q6DA 2V3XA 1XGOA 2B3HA 3L24A 1QZYA 2BWUA 4U6ZA 2IW2A 4A6WA 3PKCA 1KP0A 4PNCA 4R60A 4FUKA 1WKMA 1YJ3A 2GA2A 2GGCA 4U76A 5CNXA 4U6WA 2Q95A 4FLIA 2NQ6A 4U6EA 4U73A 4FLJA 3TAVA 1WL6A 2GU5A 4S2TP 1CHMA 5CDVA 2GTXA 2Q94A 4U1BA 3IG4A 2GU6A 2GG3A 3S6BA 4S01A 2BHAA 4MATA 4U75A 2BB7A 4IECA 3RORA 2GG8A 2BN7A 1WN1A 2GG0A 2BWSA 3FMQA 4RZYA 4FLLA 4U70A 2HOWA 2GU7A 5CE6A 2DFIA 5CIKA 4ZWPA 4B28A 3CB6A 4A6VA 4S2RP 5CLSA 4IPAA 1R58A 3IU7A 3CB5A 1KQ9A 5JFRA 4EGEA 1BOAA 2ZSGA 1BN5A 1WBQA 1XGMA 1XNZA 3BIPA 3RVAA 4KM3A 2B3LA 1YW9A 3PKAA 1YVMA 2V3ZA 5CDLA 2GG5A 2ADUA 2MATA 4JUQA 2B3KA 4FLKA 4IKTA 2GU4A 3BITA 2Q8KA 1Y1NA 5JI6A 4PV4A 4RZZA 2BH3A 4FKCA 2Q92A 1M35A 2GG9A 5FCFA 4FO8A 4U69A 4S00A 4IU6A 1B59A 2EA2A 5JHUA 2G6PA 1PV9A 4HXXA 3FMRA 1YW8A 1A16A 1C24A 1QXYA 2GG2A 4ZNGA 4ZWUA 1C27A 3IU8A 3TB5A 1R5GA 2BWVA 3L7GA 4U6JA 2V3YA 1B6AA 4RGZ1 2BWXA
chains in the Genus database with same CATH topology
1WL9A 2P98A 2EA4A 5E5BA 2BWYA 1W7VA 1JAWA 2Q93A 1O0XA 3IU9A 2NQ7A 2V6CA 3FM3A 2GZ5A 3BIQA 4U71A 5D6FA 5CDEA 5FCHA 1C23A 1W2MA 2BWWA 3D27A 2BWTA 2Q96A 2P9AA 4IKRA 1QXZA 1XGNA 2BHCA 2OAZA 3PKEA 2EVCA 1WLRA 3PKDA 4IKSA 2EVOA 1MATA 1XGSA 1C21A 4IF7A 4ZWOA 3CTZA 1KQ0A 4OOKA 4IDYA 2P99A 3MR1A 1QXWA 3MX6A 1R5HA 2GG7A 1C22A 1YW7A 4U6CA 2BHBA 4FO7A 2GGBA 4QR8A 2EVMA 3MATA 1WY2A 2OKNA 5D6EA 4Z7MA 2BHDA 3PKBA 1N51A 4IKUA 3Q6DA 2V3XA 1XGOA 2B3HA 3L24A 1QZYA 2BWUA 4U6ZA 2IW2A 4A6WA 3PKCA 1KP0A 4PNCA 4R60A 4FUKA 1WKMA 1YJ3A 2GA2A 2GGCA 4U76A 5CNXA 4U6WA 2Q95A 4FLIA 2NQ6A 4U6EA 4U73A 4FLJA 3TAVA 1WL6A 2GU5A 4S2TP 1CHMA 5CDVA 2GTXA 2Q94A 4U1BA 3IG4A 2GU6A 2GG3A 3S6BA 4S01A 2BHAA 4MATA 4U75A 2BB7A 4IECA 3RORA 2GG8A 2BN7A 1WN1A 2GG0A 2BWSA 3FMQA 4RZYA 4FLLA 4U70A 2HOWA 2GU7A 5CE6A 2DFIA 5CIKA 4ZWPA 4B28A 3CB6A 4A6VA 4S2RP 5CLSA 4IPAA 1R58A 3IU7A 3CB5A 1KQ9A 5JFRA 4EGEA 1BOAA 2ZSGA 1BN5A 1WBQA 1XGMA 1XNZA 3BIPA 3RVAA 4KM3A 2B3LA 1YW9A 3PKAA 1YVMA 2V3ZA 5CDLA 2GG5A 2ADUA 2MATA 4JUQA 2B3KA 4FLKA 4IKTA 2GU4A 3BITA 2Q8KA 1Y1NA 5JI6A 4PV4A 4RZZA 2BH3A 4FKCA 2Q92A 1M35A 2GG9A 5FCFA 4FO8A 4U69A 4S00A 4IU6A 1B59A 2EA2A 5JHUA 2G6PA 1PV9A 4HXXA 3FMRA 1YW8A 1A16A 1C24A 1QXYA 2GG2A 4ZNGA 4ZWUA 1C27A 3IU8A 3TB5A 1R5GA 2BWVA 3L7GA 4U6JA 2V3YA 1B6AA 4RGZ1 2BWXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WL9 A;  2P98 A;  2EA4 A;  5E5B A;  2BWY A;  1W7V A;  1JAW A;  2Q93 A;  1O0X A;  3IU9 A;  2NQ7 A;  2V6C A;  3FM3 A;  2GZ5 A;  3BIQ A;  4U71 A;  5D6F A;  5CDE A;  5FCH A;  1C23 A;  1W2M A;  2BWW A;  3D27 A;  2BWT A;  2Q96 A;  2P9A A;  4IKR A;  1QXZ A;  1XGN A;  2BHC A;  2OAZ A;  3PKE A;  2EVC A;  1WLR A;  3PKD A;  4IKS A;  2EVO A;  1MAT A;  1XGS A;  1C21 A;  4IF7 A;  4ZWO A;  3CTZ A;  1KQ0 A;  4OOK A;  4IDY A;  2P99 A;  3MR1 A;  1QXW A;  3MX6 A;  1R5H A;  2GG7 A;  1C22 A;  1YW7 A;  4U6C A;  2BHB A;  4FO7 A;  2GGB A;  4QR8 A;  2EVM A;  3MAT A;  1WY2 A;  2OKN A;  5D6E A;  4Z7M A;  2BHD A;  3PKB A;  1N51 A;  4IKU A;  3Q6D A;  2V3X A;  1XGO A;  2B3H A;  3L24 A;  1QZY A;  2BWU A;  4U6Z A;  2IW2 A;  4A6W A;  3PKC A;  1KP0 A;  4PNC A;  4R60 A;  4FUK A;  1WKM A;  1YJ3 A;  2GA2 A;  2GGC A;  4U76 A;  5CNX A;  4U6W A;  2Q95 A;  4FLI A;  2NQ6 A;  4U6E A;  4U73 A;  4FLJ A;  3TAV A;  1WL6 A;  2GU5 A;  4S2T P;  1CHM A;  5CDV A;  2GTX A;  2Q94 A;  4U1B A;  3IG4 A;  2GU6 A;  2GG3 A;  3S6B A;  4S01 A;  2BHA A;  4MAT A;  4U75 A;  2BB7 A;  4IEC A;  3ROR A;  2GG8 A;  2BN7 A;  1WN1 A;  2GG0 A;  2BWS A;  3FMQ A;  4RZY A;  4FLL A;  4U70 A;  2HOW A;  2GU7 A;  5CE6 A;  2DFI A;  5CIK A;  4ZWP A;  4B28 A;  3CB6 A;  4A6V A;  4S2R P;  5CLS A;  4IPA A;  1R58 A;  3IU7 A;  3CB5 A;  1KQ9 A;  5JFR A;  4EGE A;  1BOA A;  2ZSG A;  1BN5 A;  1WBQ A;  1XGM A;  1XNZ A;  3BIP A;  3RVA A;  4KM3 A;  2B3L A;  1YW9 A;  3PKA A;  1YVM A;  2V3Z A;  5CDL A;  2GG5 A;  2ADU A;  2MAT A;  4JUQ A;  2B3K A;  4FLK A;  4IKT A;  2GU4 A;  3BIT A;  2Q8K A;  1Y1N A;  5JI6 A;  4PV4 A;  4RZZ A;  2BH3 A;  4FKC A;  2Q92 A;  1M35 A;  2GG9 A;  5FCF A;  4FO8 A;  4U69 A;  4S00 A;  4IU6 A;  1B59 A;  2EA2 A;  5JHU A;  2G6P A;  1PV9 A;  4HXX A;  3FMR A;  1YW8 A;  1A16 A;  1C24 A;  1QXY A;  2GG2 A;  4ZNG A;  4ZWU A;  1C27 A;  3IU8 A;  3TB5 A;  1R5G A;  2BWV A;  3L7G A;  4U6J A;  2V3Y A;  1B6A A;  4RGZ 1;  2BWX A; 
#chains in the Genus database with same CATH topology
 1WL9 A;  2P98 A;  2EA4 A;  5E5B A;  2BWY A;  1W7V A;  1JAW A;  2Q93 A;  1O0X A;  3IU9 A;  2NQ7 A;  2V6C A;  3FM3 A;  2GZ5 A;  3BIQ A;  4U71 A;  5D6F A;  5CDE A;  5FCH A;  1C23 A;  1W2M A;  2BWW A;  3D27 A;  2BWT A;  2Q96 A;  2P9A A;  4IKR A;  1QXZ A;  1XGN A;  2BHC A;  2OAZ A;  3PKE A;  2EVC A;  1WLR A;  3PKD A;  4IKS A;  2EVO A;  1MAT A;  1XGS A;  1C21 A;  4IF7 A;  4ZWO A;  3CTZ A;  1KQ0 A;  4OOK A;  4IDY A;  2P99 A;  3MR1 A;  1QXW A;  3MX6 A;  1R5H A;  2GG7 A;  1C22 A;  1YW7 A;  4U6C A;  2BHB A;  4FO7 A;  2GGB A;  4QR8 A;  2EVM A;  3MAT A;  1WY2 A;  2OKN A;  5D6E A;  4Z7M A;  2BHD A;  3PKB A;  1N51 A;  4IKU A;  3Q6D A;  2V3X A;  1XGO A;  2B3H A;  3L24 A;  1QZY A;  2BWU A;  4U6Z A;  2IW2 A;  4A6W A;  3PKC A;  1KP0 A;  4PNC A;  4R60 A;  4FUK A;  1WKM A;  1YJ3 A;  2GA2 A;  2GGC A;  4U76 A;  5CNX A;  4U6W A;  2Q95 A;  4FLI A;  2NQ6 A;  4U6E A;  4U73 A;  4FLJ A;  3TAV A;  1WL6 A;  2GU5 A;  4S2T P;  1CHM A;  5CDV A;  2GTX A;  2Q94 A;  4U1B A;  3IG4 A;  2GU6 A;  2GG3 A;  3S6B A;  4S01 A;  2BHA A;  4MAT A;  4U75 A;  2BB7 A;  4IEC A;  3ROR A;  2GG8 A;  2BN7 A;  1WN1 A;  2GG0 A;  2BWS A;  3FMQ A;  4RZY A;  4FLL A;  4U70 A;  2HOW A;  2GU7 A;  5CE6 A;  2DFI A;  5CIK A;  4ZWP A;  4B28 A;  3CB6 A;  4A6V A;  4S2R P;  5CLS A;  4IPA A;  1R58 A;  3IU7 A;  3CB5 A;  1KQ9 A;  5JFR A;  4EGE A;  1BOA A;  2ZSG A;  1BN5 A;  1WBQ A;  1XGM A;  1XNZ A;  3BIP A;  3RVA A;  4KM3 A;  2B3L A;  1YW9 A;  3PKA A;  1YVM A;  2V3Z A;  5CDL A;  2GG5 A;  2ADU A;  2MAT A;  4JUQ A;  2B3K A;  4FLK A;  4IKT A;  2GU4 A;  3BIT A;  2Q8K A;  1Y1N A;  5JI6 A;  4PV4 A;  4RZZ A;  2BH3 A;  4FKC A;  2Q92 A;  1M35 A;  2GG9 A;  5FCF A;  4FO8 A;  4U69 A;  4S00 A;  4IU6 A;  1B59 A;  2EA2 A;  5JHU A;  2G6P A;  1PV9 A;  4HXX A;  3FMR A;  1YW8 A;  1A16 A;  1C24 A;  1QXY A;  2GG2 A;  4ZNG A;  4ZWU A;  1C27 A;  3IU8 A;  3TB5 A;  1R5G A;  2BWV A;  3L7G A;  4U6J A;  2V3Y A;  1B6A A;  4RGZ 1;  2BWX A; 
#chains in the Genus database with same CATH homology
 1WL9 A;  2P98 A;  2EA4 A;  5E5B A;  2BWY A;  1W7V A;  1JAW A;  2Q93 A;  1O0X A;  3IU9 A;  2NQ7 A;  2V6C A;  3FM3 A;  2GZ5 A;  3BIQ A;  4U71 A;  5D6F A;  5CDE A;  5FCH A;  1C23 A;  1W2M A;  2BWW A;  3D27 A;  2BWT A;  2Q96 A;  2P9A A;  4IKR A;  1QXZ A;  1XGN A;  2BHC A;  2OAZ A;  3PKE A;  2EVC A;  1WLR A;  3PKD A;  4IKS A;  2EVO A;  1MAT A;  1XGS A;  1C21 A;  4IF7 A;  4ZWO A;  3CTZ A;  1KQ0 A;  4OOK A;  4IDY A;  2P99 A;  3MR1 A;  1QXW A;  3MX6 A;  1R5H A;  2GG7 A;  1C22 A;  1YW7 A;  4U6C A;  2BHB A;  4FO7 A;  2GGB A;  4QR8 A;  2EVM A;  3MAT A;  1WY2 A;  2OKN A;  5D6E A;  4Z7M A;  2BHD A;  3PKB A;  1N51 A;  4IKU A;  3Q6D A;  2V3X A;  1XGO A;  2B3H A;  3L24 A;  1QZY A;  2BWU A;  4U6Z A;  2IW2 A;  4A6W A;  3PKC A;  1KP0 A;  4PNC A;  4R60 A;  4FUK A;  1WKM A;  1YJ3 A;  2GA2 A;  2GGC A;  4U76 A;  5CNX A;  4U6W A;  2Q95 A;  4FLI A;  2NQ6 A;  4U6E A;  4U73 A;  4FLJ A;  3TAV A;  1WL6 A;  2GU5 A;  4S2T P;  1CHM A;  5CDV A;  2GTX A;  2Q94 A;  4U1B A;  3IG4 A;  2GU6 A;  2GG3 A;  3S6B A;  4S01 A;  2BHA A;  4MAT A;  4U75 A;  2BB7 A;  4IEC A;  3ROR A;  2GG8 A;  2BN7 A;  1WN1 A;  2GG0 A;  2BWS A;  3FMQ A;  4RZY A;  4FLL A;  4U70 A;  2HOW A;  2GU7 A;  5CE6 A;  2DFI A;  5CIK A;  4ZWP A;  4B28 A;  3CB6 A;  4A6V A;  4S2R P;  5CLS A;  4IPA A;  1R58 A;  3IU7 A;  3CB5 A;  1KQ9 A;  5JFR A;  4EGE A;  1BOA A;  2ZSG A;  1BN5 A;  1WBQ A;  1XGM A;  1XNZ A;  3BIP A;  3RVA A;  4KM3 A;  2B3L A;  1YW9 A;  3PKA A;  1YVM A;  2V3Z A;  5CDL A;  2GG5 A;  2ADU A;  2MAT A;  4JUQ A;  2B3K A;  4FLK A;  4IKT A;  2GU4 A;  3BIT A;  2Q8K A;  1Y1N A;  5JI6 A;  4PV4 A;  4RZZ A;  2BH3 A;  4FKC A;  2Q92 A;  1M35 A;  2GG9 A;  5FCF A;  4FO8 A;  4U69 A;  4S00 A;  4IU6 A;  1B59 A;  2EA2 A;  5JHU A;  2G6P A;  1PV9 A;  4HXX A;  3FMR A;  1YW8 A;  1A16 A;  1C24 A;  1QXY A;  2GG2 A;  4ZNG A;  4ZWU A;  1C27 A;  3IU8 A;  3TB5 A;  1R5G A;  2BWV A;  3L7G A;  4U6J A;  2V3Y A;  1B6A A;  4RGZ 1;  2BWX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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