3PKAA

M. tuberculosis metap with bengamide analog y02, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
b'PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkaA01
1QXYA 2BWXA 3MATA 2GG3A 2IW2A 2B3HA 1C27A 1KQ0A 3IG4A 4U76A 2V3YA 4HXXA 3D27A 4S2RP 4U6WA 2GA2A 1C22A 1BN5A 2GG9A 4U75A 4ZWUA 2GGBA 3FMQA 4FKCA 2GG0A 4FLLA 2BHBA 1C23A 1N51A 3BITA 4IDYA 1QXWA 3FMRA 4IPAA 3S6BA 2BB7A 2V3ZA 2BWWA 4RGZ1 1YVMA 3IU8A 4OOKA 2GU4A 4FLJA 1WLRA 4IKUA 4U73A 1WL6A 2NQ7A 1QZYA 5E5BA 2OAZA 1KP0A 2BHAA 3L7GA 2EVOA 2Q93A 5CLSA 5CDVA 2GU6A 2MATA 3IU7A 5CDLA 3TB5A 4ZWOA 4A6WA 3MR1A 2GTXA 2GU5A 2DFIA 5CE6A 1A16A 4U1BA 2EA2A 1XGMA 3L24A 1W7VA 4PV4A 2GG2A 3PKAA 2G6PA 4S01A 4RZYA 1CHMA 3RORA 4PNCA 4U71A 2ADUA 4Z7MA 1PV9A 3MX6A 1O0XA 4RZZA 3RVAA 2BWTA 1BOAA 2GG7A 3BIQA 1XNZA 2Q8KA 3IU9A 5CNXA 2BHCA 3CTZA 2ZSGA 2B3LA 1KQ9A 2GZ5A 2P9AA 4S2TP 4MATA 3PKBA 1C24A 2OKNA 4ZWPA 4FO8A 5D6FA 1B59A 1WBQA 4FLKA 1WN1A 1XGNA 2P99A 4ZNGA 5JHUA 4FO7A 2V6CA 1YW7A 1WY2A 4EGEA 1YJ3A 2BHDA 5D6EA 5FCFA 2GG5A 5CIKA 1XGOA 1YW8A 4IECA 2Q95A 2HOWA 1R58A 4R60A 5FCHA 4U69A 1W2MA 3PKEA 4JUQA 2BWSA 1WKMA 1Y1NA 1M35A 1B6AA 1R5HA 1XGSA 2EVMA 3PKCA 2B3KA 3FM3A 4FUKA 4U6JA 2Q92A 2BWUA 2GGCA 4KM3A 1YW9A 2BN7A 4U6ZA 5CDEA 3TAVA 3CB6A 4FLIA 2Q94A 4U6CA 1WL9A 4IKRA 2V3XA 4B28A 3BIPA 1C21A 4IU6A 4U6EA 1R5GA 2BH3A 2NQ6A 2Q96A 1JAWA 2BWVA 2GU7A 4A6VA 3Q6DA 4IF7A 4IKTA 2EA4A 4S00A 5JFRA 4IKSA 4QR8A 3CB5A 5JI6A 1MATA 1QXZA 3PKDA 2EVCA 2GG8A 2BWYA 2P98A 4U70A
chains in the Genus database with same CATH superfamily
1QXYA 2BWXA 3MATA 2GG3A 2IW2A 2B3HA 1C27A 1KQ0A 3IG4A 4U76A 2V3YA 4HXXA 3D27A 4S2RP 4U6WA 2GA2A 1C22A 1BN5A 2GG9A 4U75A 4ZWUA 2GGBA 3FMQA 4FKCA 2GG0A 4FLLA 2BHBA 1C23A 1N51A 3BITA 4IDYA 1QXWA 3FMRA 4IPAA 3S6BA 2BB7A 2V3ZA 2BWWA 4RGZ1 1YVMA 3IU8A 4OOKA 2GU4A 4FLJA 1WLRA 4IKUA 4U73A 1WL6A 2NQ7A 1QZYA 5E5BA 2OAZA 1KP0A 2BHAA 3L7GA 2EVOA 2Q93A 5CLSA 5CDVA 2GU6A 2MATA 3IU7A 5CDLA 3TB5A 4ZWOA 4A6WA 3MR1A 2GTXA 2GU5A 2DFIA 5CE6A 1A16A 4U1BA 2EA2A 1XGMA 3L24A 1W7VA 4PV4A 2GG2A 3PKAA 2G6PA 4S01A 4RZYA 1CHMA 3RORA 4PNCA 4U71A 2ADUA 4Z7MA 1PV9A 3MX6A 1O0XA 4RZZA 3RVAA 2BWTA 1BOAA 2GG7A 3BIQA 1XNZA 2Q8KA 3IU9A 5CNXA 2BHCA 3CTZA 2ZSGA 2B3LA 1KQ9A 2GZ5A 2P9AA 4S2TP 4MATA 3PKBA 1C24A 2OKNA 4ZWPA 4FO8A 5D6FA 1B59A 1WBQA 4FLKA 1WN1A 1XGNA 2P99A 4ZNGA 5JHUA 4FO7A 2V6CA 1YW7A 1WY2A 4EGEA 1YJ3A 2BHDA 5D6EA 5FCFA 2GG5A 5CIKA 1XGOA 1YW8A 4IECA 2Q95A 2HOWA 1R58A 4R60A 5FCHA 4U69A 1W2MA 3PKEA 4JUQA 2BWSA 1WKMA 1Y1NA 1M35A 1B6AA 1R5HA 1XGSA 2EVMA 3PKCA 2B3KA 3FM3A 4FUKA 4U6JA 2Q92A 2BWUA 2GGCA 4KM3A 1YW9A 2BN7A 4U6ZA 5CDEA 3TAVA 3CB6A 4FLIA 2Q94A 4U6CA 1WL9A 4IKRA 2V3XA 4B28A 3BIPA 1C21A 4IU6A 4U6EA 1R5GA 2BH3A 2NQ6A 2Q96A 1JAWA 2BWVA 2GU7A 4A6VA 3Q6DA 4IF7A 4IKTA 2EA4A 4S00A 5JFRA 4IKSA 4QR8A 3CB5A 5JI6A 1MATA 1QXZA 3PKDA 2EVCA 2GG8A 2BWYA 2P98A 4U70A
chains in the Genus database with same CATH topology
1QXYA 2BWXA 3MATA 2GG3A 2IW2A 2B3HA 1C27A 1KQ0A 3IG4A 4U76A 2V3YA 4HXXA 3D27A 4S2RP 4U6WA 2GA2A 1C22A 1BN5A 2GG9A 4U75A 4ZWUA 2GGBA 3FMQA 4FKCA 2GG0A 4FLLA 2BHBA 1C23A 1N51A 3BITA 4IDYA 1QXWA 3FMRA 4IPAA 3S6BA 2BB7A 2V3ZA 2BWWA 4RGZ1 1YVMA 3IU8A 4OOKA 2GU4A 4FLJA 1WLRA 4IKUA 4U73A 1WL6A 2NQ7A 1QZYA 5E5BA 2OAZA 1KP0A 2BHAA 3L7GA 2EVOA 2Q93A 5CLSA 5CDVA 2GU6A 2MATA 3IU7A 5CDLA 3TB5A 4ZWOA 4A6WA 3MR1A 2GTXA 2GU5A 2DFIA 5CE6A 1A16A 4U1BA 2EA2A 1XGMA 3L24A 1W7VA 4PV4A 2GG2A 3PKAA 2G6PA 4S01A 4RZYA 1CHMA 3RORA 4PNCA 4U71A 2ADUA 4Z7MA 1PV9A 3MX6A 1O0XA 4RZZA 3RVAA 2BWTA 1BOAA 2GG7A 3BIQA 1XNZA 2Q8KA 3IU9A 5CNXA 2BHCA 3CTZA 2ZSGA 2B3LA 1KQ9A 2GZ5A 2P9AA 4S2TP 4MATA 3PKBA 1C24A 2OKNA 4ZWPA 4FO8A 5D6FA 1B59A 1WBQA 4FLKA 1WN1A 1XGNA 2P99A 4ZNGA 5JHUA 4FO7A 2V6CA 1YW7A 1WY2A 4EGEA 1YJ3A 2BHDA 5D6EA 5FCFA 2GG5A 5CIKA 1XGOA 1YW8A 4IECA 2Q95A 2HOWA 1R58A 4R60A 5FCHA 4U69A 1W2MA 3PKEA 4JUQA 2BWSA 1WKMA 1Y1NA 1M35A 1B6AA 1R5HA 1XGSA 2EVMA 3PKCA 2B3KA 3FM3A 4FUKA 4U6JA 2Q92A 2BWUA 2GGCA 4KM3A 1YW9A 2BN7A 4U6ZA 5CDEA 3TAVA 3CB6A 4FLIA 2Q94A 4U6CA 1WL9A 4IKRA 2V3XA 4B28A 3BIPA 1C21A 4IU6A 4U6EA 1R5GA 2BH3A 2NQ6A 2Q96A 1JAWA 2BWVA 2GU7A 4A6VA 3Q6DA 4IF7A 4IKTA 2EA4A 4S00A 5JFRA 4IKSA 4QR8A 3CB5A 5JI6A 1MATA 1QXZA 3PKDA 2EVCA 2GG8A 2BWYA 2P98A 4U70A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QXY A;  2BWX A;  3MAT A;  2GG3 A;  2IW2 A;  2B3H A;  1C27 A;  1KQ0 A;  3IG4 A;  4U76 A;  2V3Y A;  4HXX A;  3D27 A;  4S2R P;  4U6W A;  2GA2 A;  1C22 A;  1BN5 A;  2GG9 A;  4U75 A;  4ZWU A;  2GGB A;  3FMQ A;  4FKC A;  2GG0 A;  4FLL A;  2BHB A;  1C23 A;  1N51 A;  3BIT A;  4IDY A;  1QXW A;  3FMR A;  4IPA A;  3S6B A;  2BB7 A;  2V3Z A;  2BWW A;  4RGZ 1;  1YVM A;  3IU8 A;  4OOK A;  2GU4 A;  4FLJ A;  1WLR A;  4IKU A;  4U73 A;  1WL6 A;  2NQ7 A;  1QZY A;  5E5B A;  2OAZ A;  1KP0 A;  2BHA A;  3L7G A;  2EVO A;  2Q93 A;  5CLS A;  5CDV A;  2GU6 A;  2MAT A;  3IU7 A;  5CDL A;  3TB5 A;  4ZWO A;  4A6W A;  3MR1 A;  2GTX A;  2GU5 A;  2DFI A;  5CE6 A;  1A16 A;  4U1B A;  2EA2 A;  1XGM A;  3L24 A;  1W7V A;  4PV4 A;  2GG2 A;  3PKA A;  2G6P A;  4S01 A;  4RZY A;  1CHM A;  3ROR A;  4PNC A;  4U71 A;  2ADU A;  4Z7M A;  1PV9 A;  3MX6 A;  1O0X A;  4RZZ A;  3RVA A;  2BWT A;  1BOA A;  2GG7 A;  3BIQ A;  1XNZ A;  2Q8K A;  3IU9 A;  5CNX A;  2BHC A;  3CTZ A;  2ZSG A;  2B3L A;  1KQ9 A;  2GZ5 A;  2P9A A;  4S2T P;  4MAT A;  3PKB A;  1C24 A;  2OKN A;  4ZWP A;  4FO8 A;  5D6F A;  1B59 A;  1WBQ A;  4FLK A;  1WN1 A;  1XGN A;  2P99 A;  4ZNG A;  5JHU A;  4FO7 A;  2V6C A;  1YW7 A;  1WY2 A;  4EGE A;  1YJ3 A;  2BHD A;  5D6E A;  5FCF A;  2GG5 A;  5CIK A;  1XGO A;  1YW8 A;  4IEC A;  2Q95 A;  2HOW A;  1R58 A;  4R60 A;  5FCH A;  4U69 A;  1W2M A;  3PKE A;  4JUQ A;  2BWS A;  1WKM A;  1Y1N A;  1M35 A;  1B6A A;  1R5H A;  1XGS A;  2EVM A;  3PKC A;  2B3K A;  3FM3 A;  4FUK A;  4U6J A;  2Q92 A;  2BWU A;  2GGC A;  4KM3 A;  1YW9 A;  2BN7 A;  4U6Z A;  5CDE A;  3TAV A;  3CB6 A;  4FLI A;  2Q94 A;  4U6C A;  1WL9 A;  4IKR A;  2V3X A;  4B28 A;  3BIP A;  1C21 A;  4IU6 A;  4U6E A;  1R5G A;  2BH3 A;  2NQ6 A;  2Q96 A;  1JAW A;  2BWV A;  2GU7 A;  4A6V A;  3Q6D A;  4IF7 A;  4IKT A;  2EA4 A;  4S00 A;  5JFR A;  4IKS A;  4QR8 A;  3CB5 A;  5JI6 A;  1MAT A;  1QXZ A;  3PKD A;  2EVC A;  2GG8 A;  2BWY A;  2P98 A;  4U70 A; 
#chains in the Genus database with same CATH topology
 1QXY A;  2BWX A;  3MAT A;  2GG3 A;  2IW2 A;  2B3H A;  1C27 A;  1KQ0 A;  3IG4 A;  4U76 A;  2V3Y A;  4HXX A;  3D27 A;  4S2R P;  4U6W A;  2GA2 A;  1C22 A;  1BN5 A;  2GG9 A;  4U75 A;  4ZWU A;  2GGB A;  3FMQ A;  4FKC A;  2GG0 A;  4FLL A;  2BHB A;  1C23 A;  1N51 A;  3BIT A;  4IDY A;  1QXW A;  3FMR A;  4IPA A;  3S6B A;  2BB7 A;  2V3Z A;  2BWW A;  4RGZ 1;  1YVM A;  3IU8 A;  4OOK A;  2GU4 A;  4FLJ A;  1WLR A;  4IKU A;  4U73 A;  1WL6 A;  2NQ7 A;  1QZY A;  5E5B A;  2OAZ A;  1KP0 A;  2BHA A;  3L7G A;  2EVO A;  2Q93 A;  5CLS A;  5CDV A;  2GU6 A;  2MAT A;  3IU7 A;  5CDL A;  3TB5 A;  4ZWO A;  4A6W A;  3MR1 A;  2GTX A;  2GU5 A;  2DFI A;  5CE6 A;  1A16 A;  4U1B A;  2EA2 A;  1XGM A;  3L24 A;  1W7V A;  4PV4 A;  2GG2 A;  3PKA A;  2G6P A;  4S01 A;  4RZY A;  1CHM A;  3ROR A;  4PNC A;  4U71 A;  2ADU A;  4Z7M A;  1PV9 A;  3MX6 A;  1O0X A;  4RZZ A;  3RVA A;  2BWT A;  1BOA A;  2GG7 A;  3BIQ A;  1XNZ A;  2Q8K A;  3IU9 A;  5CNX A;  2BHC A;  3CTZ A;  2ZSG A;  2B3L A;  1KQ9 A;  2GZ5 A;  2P9A A;  4S2T P;  4MAT A;  3PKB A;  1C24 A;  2OKN A;  4ZWP A;  4FO8 A;  5D6F A;  1B59 A;  1WBQ A;  4FLK A;  1WN1 A;  1XGN A;  2P99 A;  4ZNG A;  5JHU A;  4FO7 A;  2V6C A;  1YW7 A;  1WY2 A;  4EGE A;  1YJ3 A;  2BHD A;  5D6E A;  5FCF A;  2GG5 A;  5CIK A;  1XGO A;  1YW8 A;  4IEC A;  2Q95 A;  2HOW A;  1R58 A;  4R60 A;  5FCH A;  4U69 A;  1W2M A;  3PKE A;  4JUQ A;  2BWS A;  1WKM A;  1Y1N A;  1M35 A;  1B6A A;  1R5H A;  1XGS A;  2EVM A;  3PKC A;  2B3K A;  3FM3 A;  4FUK A;  4U6J A;  2Q92 A;  2BWU A;  2GGC A;  4KM3 A;  1YW9 A;  2BN7 A;  4U6Z A;  5CDE A;  3TAV A;  3CB6 A;  4FLI A;  2Q94 A;  4U6C A;  1WL9 A;  4IKR A;  2V3X A;  4B28 A;  3BIP A;  1C21 A;  4IU6 A;  4U6E A;  1R5G A;  2BH3 A;  2NQ6 A;  2Q96 A;  1JAW A;  2BWV A;  2GU7 A;  4A6V A;  3Q6D A;  4IF7 A;  4IKT A;  2EA4 A;  4S00 A;  5JFR A;  4IKS A;  4QR8 A;  3CB5 A;  5JI6 A;  1MAT A;  1QXZ A;  3PKD A;  2EVC A;  2GG8 A;  2BWY A;  2P98 A;  4U70 A; 
#chains in the Genus database with same CATH homology
 1QXY A;  2BWX A;  3MAT A;  2GG3 A;  2IW2 A;  2B3H A;  1C27 A;  1KQ0 A;  3IG4 A;  4U76 A;  2V3Y A;  4HXX A;  3D27 A;  4S2R P;  4U6W A;  2GA2 A;  1C22 A;  1BN5 A;  2GG9 A;  4U75 A;  4ZWU A;  2GGB A;  3FMQ A;  4FKC A;  2GG0 A;  4FLL A;  2BHB A;  1C23 A;  1N51 A;  3BIT A;  4IDY A;  1QXW A;  3FMR A;  4IPA A;  3S6B A;  2BB7 A;  2V3Z A;  2BWW A;  4RGZ 1;  1YVM A;  3IU8 A;  4OOK A;  2GU4 A;  4FLJ A;  1WLR A;  4IKU A;  4U73 A;  1WL6 A;  2NQ7 A;  1QZY A;  5E5B A;  2OAZ A;  1KP0 A;  2BHA A;  3L7G A;  2EVO A;  2Q93 A;  5CLS A;  5CDV A;  2GU6 A;  2MAT A;  3IU7 A;  5CDL A;  3TB5 A;  4ZWO A;  4A6W A;  3MR1 A;  2GTX A;  2GU5 A;  2DFI A;  5CE6 A;  1A16 A;  4U1B A;  2EA2 A;  1XGM A;  3L24 A;  1W7V A;  4PV4 A;  2GG2 A;  3PKA A;  2G6P A;  4S01 A;  4RZY A;  1CHM A;  3ROR A;  4PNC A;  4U71 A;  2ADU A;  4Z7M A;  1PV9 A;  3MX6 A;  1O0X A;  4RZZ A;  3RVA A;  2BWT A;  1BOA A;  2GG7 A;  3BIQ A;  1XNZ A;  2Q8K A;  3IU9 A;  5CNX A;  2BHC A;  3CTZ A;  2ZSG A;  2B3L A;  1KQ9 A;  2GZ5 A;  2P9A A;  4S2T P;  4MAT A;  3PKB A;  1C24 A;  2OKN A;  4ZWP A;  4FO8 A;  5D6F A;  1B59 A;  1WBQ A;  4FLK A;  1WN1 A;  1XGN A;  2P99 A;  4ZNG A;  5JHU A;  4FO7 A;  2V6C A;  1YW7 A;  1WY2 A;  4EGE A;  1YJ3 A;  2BHD A;  5D6E A;  5FCF A;  2GG5 A;  5CIK A;  1XGO A;  1YW8 A;  4IEC A;  2Q95 A;  2HOW A;  1R58 A;  4R60 A;  5FCH A;  4U69 A;  1W2M A;  3PKE A;  4JUQ A;  2BWS A;  1WKM A;  1Y1N A;  1M35 A;  1B6A A;  1R5H A;  1XGS A;  2EVM A;  3PKC A;  2B3K A;  3FM3 A;  4FUK A;  4U6J A;  2Q92 A;  2BWU A;  2GGC A;  4KM3 A;  1YW9 A;  2BN7 A;  4U6Z A;  5CDE A;  3TAV A;  3CB6 A;  4FLI A;  2Q94 A;  4U6C A;  1WL9 A;  4IKR A;  2V3X A;  4B28 A;  3BIP A;  1C21 A;  4IU6 A;  4U6E A;  1R5G A;  2BH3 A;  2NQ6 A;  2Q96 A;  1JAW A;  2BWV A;  2GU7 A;  4A6V A;  3Q6D A;  4IF7 A;  4IKT A;  2EA4 A;  4S00 A;  5JFR A;  4IKS A;  4QR8 A;  3CB5 A;  5JI6 A;  1MAT A;  1QXZ A;  3PKD A;  2EVC A;  2GG8 A;  2BWY A;  2P98 A;  4U70 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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