3PKAA

M. tuberculosis metap with bengamide analog y02, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Mycobacterium tuberculosis
molecule keywords Methionine aminopeptidase
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkaA01
1XGSA 3S6BA 1C27A 2DFIA 2GG2A 2GZ5A 2V6CA 4S00A 4FO8A 2GGBA 2IW2A 5CE6A 2BWXA 2BHBA 2BWUA 1M35A 4FLLA 4MATA 2P98A 4RZZA 4PV4A 2GG5A 3BITA 2GU5A 5CDLA 1XGNA 4RGZ1 4U6ZA 2NQ6A 2BHAA 2Q92A 1QXWA 2ADUA 4U73A 4S2RP 3FMRA 2MATA 2GG7A 5D6EA 3D27A 2EVOA 2GU4A 2V3ZA 5FCFA 1WN1A 1WLRA 4JUQA 4S01A 3Q6DA 5CDVA 4Z7MA 1CHMA 3BIPA 5JHUA 3MATA 4ZWOA 1N51A 2Q93A 2Q95A 1PV9A 4U69A 2BWVA 1C22A 1WKMA 4IDYA 2Q96A 1B6AA 3CB6A 4U6EA 1JAWA 1R5HA 1R58A 1YVMA 2NQ7A 3PKEA 4U76A 4A6VA 4R60A 1KQ9A 4ZNGA 2EA2A 3PKDA 2Q8KA 4KM3A 1YJ3A 2GU7A 3IG4A 3RORA 3BIQA 5FCHA 4FO7A 1KQ0A 2ZSGA 1XGMA 1WL9A 4U75A 5CLSA 2B3KA 4U1BA 1QXYA 4U6WA 5D6FA 1W2MA 4U70A 2GGCA 2GTXA 3PKBA 1R5GA 2BHCA 1XNZA 2EVMA 1QXZA 1YW9A 1A16A 1WY2A 1W7VA 2EVCA 4IPAA 1B59A 1XGOA 1YW8A 4IU6A 4ZWUA 1YW7A 1BOAA 1C21A 4U6CA 4U71A 2V3XA 2Q94A 4FKCA 2GG8A 4RZYA 1Y1NA 2GA2A 3MR1A 1O0XA 5CIKA 5CNXA 2BN7A 5E5BA 2BWWA 4B28A 3IU9A 1C23A 3IU7A 2EA4A 2GG9A 3L24A 3PKCA 3L7GA 3TAVA 3CTZA 4EGEA 4IKRA 4QR8A 4FUKA 5JI6A 2BH3A 3FMQA 1WL6A 3FM3A 2OKNA 4A6WA 4IECA 2OAZA 2G6PA 4OOKA 2GU6A 3RVAA 1QZYA 1WBQA 2BWTA 4IF7A 5JFRA 4HXXA 1C24A 4U6JA 1MATA 4PNCA 5CDEA 2B3HA 1KP0A 2V3YA 2P9AA 4IKUA 2GG3A 4ZWPA 3IU8A 3CB5A 3PKAA 2GG0A 4FLIA 3TB5A 2P99A 2HOWA 4FLJA 2BHDA 2BB7A 4IKSA 4IKTA 4FLKA 2B3LA 4S2TP 3MX6A 2BWSA 2BWYA 1BN5A
chains in the Genus database with same CATH superfamily
1XGSA 3S6BA 1C27A 2DFIA 2GG2A 2GZ5A 2V6CA 4S00A 4FO8A 2GGBA 2IW2A 5CE6A 2BWXA 2BHBA 2BWUA 1M35A 4FLLA 4MATA 2P98A 4RZZA 4PV4A 2GG5A 3BITA 2GU5A 5CDLA 1XGNA 4RGZ1 4U6ZA 2NQ6A 2BHAA 2Q92A 1QXWA 2ADUA 4U73A 4S2RP 3FMRA 2MATA 2GG7A 5D6EA 3D27A 2EVOA 2GU4A 2V3ZA 5FCFA 1WN1A 1WLRA 4JUQA 4S01A 3Q6DA 5CDVA 4Z7MA 1CHMA 3BIPA 5JHUA 3MATA 4ZWOA 1N51A 2Q93A 2Q95A 1PV9A 4U69A 2BWVA 1C22A 1WKMA 4IDYA 2Q96A 1B6AA 3CB6A 4U6EA 1JAWA 1R5HA 1R58A 1YVMA 2NQ7A 3PKEA 4U76A 4A6VA 4R60A 1KQ9A 4ZNGA 2EA2A 3PKDA 2Q8KA 4KM3A 1YJ3A 2GU7A 3IG4A 3RORA 3BIQA 5FCHA 4FO7A 1KQ0A 2ZSGA 1XGMA 1WL9A 4U75A 5CLSA 2B3KA 4U1BA 1QXYA 4U6WA 5D6FA 1W2MA 4U70A 2GGCA 2GTXA 3PKBA 1R5GA 2BHCA 1XNZA 2EVMA 1QXZA 1YW9A 1A16A 1WY2A 1W7VA 2EVCA 4IPAA 1B59A 1XGOA 1YW8A 4IU6A 4ZWUA 1YW7A 1BOAA 1C21A 4U6CA 4U71A 2V3XA 2Q94A 4FKCA 2GG8A 4RZYA 1Y1NA 2GA2A 3MR1A 1O0XA 5CIKA 5CNXA 2BN7A 5E5BA 2BWWA 4B28A 3IU9A 1C23A 3IU7A 2EA4A 2GG9A 3L24A 3PKCA 3L7GA 3TAVA 3CTZA 4EGEA 4IKRA 4QR8A 4FUKA 5JI6A 2BH3A 3FMQA 1WL6A 3FM3A 2OKNA 4A6WA 4IECA 2OAZA 2G6PA 4OOKA 2GU6A 3RVAA 1QZYA 1WBQA 2BWTA 4IF7A 5JFRA 4HXXA 1C24A 4U6JA 1MATA 4PNCA 5CDEA 2B3HA 1KP0A 2V3YA 2P9AA 4IKUA 2GG3A 4ZWPA 3IU8A 3CB5A 3PKAA 2GG0A 4FLIA 3TB5A 2P99A 2HOWA 4FLJA 2BHDA 2BB7A 4IKSA 4IKTA 4FLKA 2B3LA 4S2TP 3MX6A 2BWSA 2BWYA 1BN5A
chains in the Genus database with same CATH topology
1XGSA 3S6BA 1C27A 2DFIA 2GG2A 2GZ5A 2V6CA 4S00A 4FO8A 2GGBA 2IW2A 5CE6A 2BWXA 2BHBA 2BWUA 1M35A 4FLLA 4MATA 2P98A 4RZZA 4PV4A 2GG5A 3BITA 2GU5A 5CDLA 1XGNA 4RGZ1 4U6ZA 2NQ6A 2BHAA 2Q92A 1QXWA 2ADUA 4U73A 4S2RP 3FMRA 2MATA 2GG7A 5D6EA 3D27A 2EVOA 2GU4A 2V3ZA 5FCFA 1WN1A 1WLRA 4JUQA 4S01A 3Q6DA 5CDVA 4Z7MA 1CHMA 3BIPA 5JHUA 3MATA 4ZWOA 1N51A 2Q93A 2Q95A 1PV9A 4U69A 2BWVA 1C22A 1WKMA 4IDYA 2Q96A 1B6AA 3CB6A 4U6EA 1JAWA 1R5HA 1R58A 1YVMA 2NQ7A 3PKEA 4U76A 4A6VA 4R60A 1KQ9A 4ZNGA 2EA2A 3PKDA 2Q8KA 4KM3A 1YJ3A 2GU7A 3IG4A 3RORA 3BIQA 5FCHA 4FO7A 1KQ0A 2ZSGA 1XGMA 1WL9A 4U75A 5CLSA 2B3KA 4U1BA 1QXYA 4U6WA 5D6FA 1W2MA 4U70A 2GGCA 2GTXA 3PKBA 1R5GA 2BHCA 1XNZA 2EVMA 1QXZA 1YW9A 1A16A 1WY2A 1W7VA 2EVCA 4IPAA 1B59A 1XGOA 1YW8A 4IU6A 4ZWUA 1YW7A 1BOAA 1C21A 4U6CA 4U71A 2V3XA 2Q94A 4FKCA 2GG8A 4RZYA 1Y1NA 2GA2A 3MR1A 1O0XA 5CIKA 5CNXA 2BN7A 5E5BA 2BWWA 4B28A 3IU9A 1C23A 3IU7A 2EA4A 2GG9A 3L24A 3PKCA 3L7GA 3TAVA 3CTZA 4EGEA 4IKRA 4QR8A 4FUKA 5JI6A 2BH3A 3FMQA 1WL6A 3FM3A 2OKNA 4A6WA 4IECA 2OAZA 2G6PA 4OOKA 2GU6A 3RVAA 1QZYA 1WBQA 2BWTA 4IF7A 5JFRA 4HXXA 1C24A 4U6JA 1MATA 4PNCA 5CDEA 2B3HA 1KP0A 2V3YA 2P9AA 4IKUA 2GG3A 4ZWPA 3IU8A 3CB5A 3PKAA 2GG0A 4FLIA 3TB5A 2P99A 2HOWA 4FLJA 2BHDA 2BB7A 4IKSA 4IKTA 4FLKA 2B3LA 4S2TP 3MX6A 2BWSA 2BWYA 1BN5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XGS A;  3S6B A;  1C27 A;  2DFI A;  2GG2 A;  2GZ5 A;  2V6C A;  4S00 A;  4FO8 A;  2GGB A;  2IW2 A;  5CE6 A;  2BWX A;  2BHB A;  2BWU A;  1M35 A;  4FLL A;  4MAT A;  2P98 A;  4RZZ A;  4PV4 A;  2GG5 A;  3BIT A;  2GU5 A;  5CDL A;  1XGN A;  4RGZ 1;  4U6Z A;  2NQ6 A;  2BHA A;  2Q92 A;  1QXW A;  2ADU A;  4U73 A;  4S2R P;  3FMR A;  2MAT A;  2GG7 A;  5D6E A;  3D27 A;  2EVO A;  2GU4 A;  2V3Z A;  5FCF A;  1WN1 A;  1WLR A;  4JUQ A;  4S01 A;  3Q6D A;  5CDV A;  4Z7M A;  1CHM A;  3BIP A;  5JHU A;  3MAT A;  4ZWO A;  1N51 A;  2Q93 A;  2Q95 A;  1PV9 A;  4U69 A;  2BWV A;  1C22 A;  1WKM A;  4IDY A;  2Q96 A;  1B6A A;  3CB6 A;  4U6E A;  1JAW A;  1R5H A;  1R58 A;  1YVM A;  2NQ7 A;  3PKE A;  4U76 A;  4A6V A;  4R60 A;  1KQ9 A;  4ZNG A;  2EA2 A;  3PKD A;  2Q8K A;  4KM3 A;  1YJ3 A;  2GU7 A;  3IG4 A;  3ROR A;  3BIQ A;  5FCH A;  4FO7 A;  1KQ0 A;  2ZSG A;  1XGM A;  1WL9 A;  4U75 A;  5CLS A;  2B3K A;  4U1B A;  1QXY A;  4U6W A;  5D6F A;  1W2M A;  4U70 A;  2GGC A;  2GTX A;  3PKB A;  1R5G A;  2BHC A;  1XNZ A;  2EVM A;  1QXZ A;  1YW9 A;  1A16 A;  1WY2 A;  1W7V A;  2EVC A;  4IPA A;  1B59 A;  1XGO A;  1YW8 A;  4IU6 A;  4ZWU A;  1YW7 A;  1BOA A;  1C21 A;  4U6C A;  4U71 A;  2V3X A;  2Q94 A;  4FKC A;  2GG8 A;  4RZY A;  1Y1N A;  2GA2 A;  3MR1 A;  1O0X A;  5CIK A;  5CNX A;  2BN7 A;  5E5B A;  2BWW A;  4B28 A;  3IU9 A;  1C23 A;  3IU7 A;  2EA4 A;  2GG9 A;  3L24 A;  3PKC A;  3L7G A;  3TAV A;  3CTZ A;  4EGE A;  4IKR A;  4QR8 A;  4FUK A;  5JI6 A;  2BH3 A;  3FMQ A;  1WL6 A;  3FM3 A;  2OKN A;  4A6W A;  4IEC A;  2OAZ A;  2G6P A;  4OOK A;  2GU6 A;  3RVA A;  1QZY A;  1WBQ A;  2BWT A;  4IF7 A;  5JFR A;  4HXX A;  1C24 A;  4U6J A;  1MAT A;  4PNC A;  5CDE A;  2B3H A;  1KP0 A;  2V3Y A;  2P9A A;  4IKU A;  2GG3 A;  4ZWP A;  3IU8 A;  3CB5 A;  3PKA A;  2GG0 A;  4FLI A;  3TB5 A;  2P99 A;  2HOW A;  4FLJ A;  2BHD A;  2BB7 A;  4IKS A;  4IKT A;  4FLK A;  2B3L A;  4S2T P;  3MX6 A;  2BWS A;  2BWY A;  1BN5 A; 
#chains in the Genus database with same CATH topology
 1XGS A;  3S6B A;  1C27 A;  2DFI A;  2GG2 A;  2GZ5 A;  2V6C A;  4S00 A;  4FO8 A;  2GGB A;  2IW2 A;  5CE6 A;  2BWX A;  2BHB A;  2BWU A;  1M35 A;  4FLL A;  4MAT A;  2P98 A;  4RZZ A;  4PV4 A;  2GG5 A;  3BIT A;  2GU5 A;  5CDL A;  1XGN A;  4RGZ 1;  4U6Z A;  2NQ6 A;  2BHA A;  2Q92 A;  1QXW A;  2ADU A;  4U73 A;  4S2R P;  3FMR A;  2MAT A;  2GG7 A;  5D6E A;  3D27 A;  2EVO A;  2GU4 A;  2V3Z A;  5FCF A;  1WN1 A;  1WLR A;  4JUQ A;  4S01 A;  3Q6D A;  5CDV A;  4Z7M A;  1CHM A;  3BIP A;  5JHU A;  3MAT A;  4ZWO A;  1N51 A;  2Q93 A;  2Q95 A;  1PV9 A;  4U69 A;  2BWV A;  1C22 A;  1WKM A;  4IDY A;  2Q96 A;  1B6A A;  3CB6 A;  4U6E A;  1JAW A;  1R5H A;  1R58 A;  1YVM A;  2NQ7 A;  3PKE A;  4U76 A;  4A6V A;  4R60 A;  1KQ9 A;  4ZNG A;  2EA2 A;  3PKD A;  2Q8K A;  4KM3 A;  1YJ3 A;  2GU7 A;  3IG4 A;  3ROR A;  3BIQ A;  5FCH A;  4FO7 A;  1KQ0 A;  2ZSG A;  1XGM A;  1WL9 A;  4U75 A;  5CLS A;  2B3K A;  4U1B A;  1QXY A;  4U6W A;  5D6F A;  1W2M A;  4U70 A;  2GGC A;  2GTX A;  3PKB A;  1R5G A;  2BHC A;  1XNZ A;  2EVM A;  1QXZ A;  1YW9 A;  1A16 A;  1WY2 A;  1W7V A;  2EVC A;  4IPA A;  1B59 A;  1XGO A;  1YW8 A;  4IU6 A;  4ZWU A;  1YW7 A;  1BOA A;  1C21 A;  4U6C A;  4U71 A;  2V3X A;  2Q94 A;  4FKC A;  2GG8 A;  4RZY A;  1Y1N A;  2GA2 A;  3MR1 A;  1O0X A;  5CIK A;  5CNX A;  2BN7 A;  5E5B A;  2BWW A;  4B28 A;  3IU9 A;  1C23 A;  3IU7 A;  2EA4 A;  2GG9 A;  3L24 A;  3PKC A;  3L7G A;  3TAV A;  3CTZ A;  4EGE A;  4IKR A;  4QR8 A;  4FUK A;  5JI6 A;  2BH3 A;  3FMQ A;  1WL6 A;  3FM3 A;  2OKN A;  4A6W A;  4IEC A;  2OAZ A;  2G6P A;  4OOK A;  2GU6 A;  3RVA A;  1QZY A;  1WBQ A;  2BWT A;  4IF7 A;  5JFR A;  4HXX A;  1C24 A;  4U6J A;  1MAT A;  4PNC A;  5CDE A;  2B3H A;  1KP0 A;  2V3Y A;  2P9A A;  4IKU A;  2GG3 A;  4ZWP A;  3IU8 A;  3CB5 A;  3PKA A;  2GG0 A;  4FLI A;  3TB5 A;  2P99 A;  2HOW A;  4FLJ A;  2BHD A;  2BB7 A;  4IKS A;  4IKT A;  4FLK A;  2B3L A;  4S2T P;  3MX6 A;  2BWS A;  2BWY A;  1BN5 A; 
#chains in the Genus database with same CATH homology
 1XGS A;  3S6B A;  1C27 A;  2DFI A;  2GG2 A;  2GZ5 A;  2V6C A;  4S00 A;  4FO8 A;  2GGB A;  2IW2 A;  5CE6 A;  2BWX A;  2BHB A;  2BWU A;  1M35 A;  4FLL A;  4MAT A;  2P98 A;  4RZZ A;  4PV4 A;  2GG5 A;  3BIT A;  2GU5 A;  5CDL A;  1XGN A;  4RGZ 1;  4U6Z A;  2NQ6 A;  2BHA A;  2Q92 A;  1QXW A;  2ADU A;  4U73 A;  4S2R P;  3FMR A;  2MAT A;  2GG7 A;  5D6E A;  3D27 A;  2EVO A;  2GU4 A;  2V3Z A;  5FCF A;  1WN1 A;  1WLR A;  4JUQ A;  4S01 A;  3Q6D A;  5CDV A;  4Z7M A;  1CHM A;  3BIP A;  5JHU A;  3MAT A;  4ZWO A;  1N51 A;  2Q93 A;  2Q95 A;  1PV9 A;  4U69 A;  2BWV A;  1C22 A;  1WKM A;  4IDY A;  2Q96 A;  1B6A A;  3CB6 A;  4U6E A;  1JAW A;  1R5H A;  1R58 A;  1YVM A;  2NQ7 A;  3PKE A;  4U76 A;  4A6V A;  4R60 A;  1KQ9 A;  4ZNG A;  2EA2 A;  3PKD A;  2Q8K A;  4KM3 A;  1YJ3 A;  2GU7 A;  3IG4 A;  3ROR A;  3BIQ A;  5FCH A;  4FO7 A;  1KQ0 A;  2ZSG A;  1XGM A;  1WL9 A;  4U75 A;  5CLS A;  2B3K A;  4U1B A;  1QXY A;  4U6W A;  5D6F A;  1W2M A;  4U70 A;  2GGC A;  2GTX A;  3PKB A;  1R5G A;  2BHC A;  1XNZ A;  2EVM A;  1QXZ A;  1YW9 A;  1A16 A;  1WY2 A;  1W7V A;  2EVC A;  4IPA A;  1B59 A;  1XGO A;  1YW8 A;  4IU6 A;  4ZWU A;  1YW7 A;  1BOA A;  1C21 A;  4U6C A;  4U71 A;  2V3X A;  2Q94 A;  4FKC A;  2GG8 A;  4RZY A;  1Y1N A;  2GA2 A;  3MR1 A;  1O0X A;  5CIK A;  5CNX A;  2BN7 A;  5E5B A;  2BWW A;  4B28 A;  3IU9 A;  1C23 A;  3IU7 A;  2EA4 A;  2GG9 A;  3L24 A;  3PKC A;  3L7G A;  3TAV A;  3CTZ A;  4EGE A;  4IKR A;  4QR8 A;  4FUK A;  5JI6 A;  2BH3 A;  3FMQ A;  1WL6 A;  3FM3 A;  2OKN A;  4A6W A;  4IEC A;  2OAZ A;  2G6P A;  4OOK A;  2GU6 A;  3RVA A;  1QZY A;  1WBQ A;  2BWT A;  4IF7 A;  5JFR A;  4HXX A;  1C24 A;  4U6J A;  1MAT A;  4PNC A;  5CDE A;  2B3H A;  1KP0 A;  2V3Y A;  2P9A A;  4IKU A;  2GG3 A;  4ZWP A;  3IU8 A;  3CB5 A;  3PKA A;  2GG0 A;  4FLI A;  3TB5 A;  2P99 A;  2HOW A;  4FLJ A;  2BHD A;  2BB7 A;  4IKS A;  4IKT A;  4FLK A;  2B3L A;  4S2T P;  3MX6 A;  2BWS A;  2BWY A;  1BN5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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