3PKAA

M. tuberculosis metap with bengamide analog y02, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkaA01
2P99A 4IECA 5D6EA 4IPAA 2GG7A 1YW8A 2G6PA 2EA4A 4A6WA 1W2MA 2Q93A 1C27A 4IKUA 4U6ZA 1QXWA 2V3ZA 4HXXA 5E5BA 4S00A 4U73A 4FLKA 4ZNGA 2NQ7A 3RVAA 2ZSGA 4OOKA 3BITA 3L24A 4R60A 2GU7A 1Y1NA 4S01A 2EVOA 1QZYA 1YW7A 1M35A 3FMQA 1XGSA 2B3KA 4RGZ1 1KP0A 1JAWA 5FCHA 2MATA 3FMRA 1QXZA 2BN7A 1O0XA 3PKAA 2Q96A 4FO8A 4EGEA 2GGCA 2OKNA 1CHMA 4PV4A 4IKRA 4FKCA 4MATA 1BN5A 1XNZA 2GG5A 1KQ9A 4A6VA 5CDVA 4PNCA 2BHCA 3MR1A 5CIKA 2EVMA 2GG9A 4IKTA 3PKCA 5D6FA 2Q95A 4U6CA 5JHUA 3BIPA 4FO7A 4S2RP 2Q8KA 2GU4A 4JUQA 3FM3A 2BH3A 1XGOA 2GTXA 1C21A 1R58A 1MATA 2BWYA 1XGMA 1WY2A 1KQ0A 2GU6A 1YW9A 1B59A 2BWVA 2V3XA 1WN1A 1WKMA 2BHAA 2GG8A 4B28A 4QR8A 3L7GA 1XGNA 4RZZA 2NQ6A 4ZWPA 2HOWA 1PV9A 1W7VA 4U75A 4Z7MA 3BIQA 3PKBA 3MX6A 2Q94A 4U1BA 2GG2A 2GZ5A 2V3YA 1QXYA 1B6AA 2BWSA 3IG4A 4IU6A 2P98A 2ADUA 3TB5A 2DFIA 4IKSA 4IF7A 4RZYA 2V6CA 2BWWA 1R5GA 5FCFA 5CE6A 3PKEA 4KM3A 1BOAA 2BHBA 2GG3A 2BHDA 2BWTA 4U76A 4S2TP 1C23A 5CLSA 2BB7A 5CDEA 2EVCA 2GA2A 3IU7A 3RORA 3TAVA 3IU9A 4FLJA 4U6JA 5JI6A 2BWUA 3CB6A 3MATA 1WBQA 1A16A 3Q6DA 4U6EA 4U6WA 1WLRA 5CNXA 3CTZA 5JFRA 1C24A 4ZWUA 3CB5A 3D27A 1YVMA 1C22A 4U71A 2EA2A 2GU5A 2P9AA 2IW2A 2B3HA 4IDYA 3PKDA 1R5HA 2B3LA 4U69A 4FLIA 1WL6A 1WL9A 2Q92A 3IU8A 3S6BA 5CDLA 2OAZA 4U70A 4FUKA 4FLLA 2GGBA 2BWXA 1N51A 4ZWOA 1YJ3A 2GG0A
chains in the Genus database with same CATH superfamily
2P99A 4IECA 5D6EA 4IPAA 2GG7A 1YW8A 2G6PA 2EA4A 4A6WA 1W2MA 2Q93A 1C27A 4IKUA 4U6ZA 1QXWA 2V3ZA 4HXXA 5E5BA 4S00A 4U73A 4FLKA 4ZNGA 2NQ7A 3RVAA 2ZSGA 4OOKA 3BITA 3L24A 4R60A 2GU7A 1Y1NA 4S01A 2EVOA 1QZYA 1YW7A 1M35A 3FMQA 1XGSA 2B3KA 4RGZ1 1KP0A 1JAWA 5FCHA 2MATA 3FMRA 1QXZA 2BN7A 1O0XA 3PKAA 2Q96A 4FO8A 4EGEA 2GGCA 2OKNA 1CHMA 4PV4A 4IKRA 4FKCA 4MATA 1BN5A 1XNZA 2GG5A 1KQ9A 4A6VA 5CDVA 4PNCA 2BHCA 3MR1A 5CIKA 2EVMA 2GG9A 4IKTA 3PKCA 5D6FA 2Q95A 4U6CA 5JHUA 3BIPA 4FO7A 4S2RP 2Q8KA 2GU4A 4JUQA 3FM3A 2BH3A 1XGOA 2GTXA 1C21A 1R58A 1MATA 2BWYA 1XGMA 1WY2A 1KQ0A 2GU6A 1YW9A 1B59A 2BWVA 2V3XA 1WN1A 1WKMA 2BHAA 2GG8A 4B28A 4QR8A 3L7GA 1XGNA 4RZZA 2NQ6A 4ZWPA 2HOWA 1PV9A 1W7VA 4U75A 4Z7MA 3BIQA 3PKBA 3MX6A 2Q94A 4U1BA 2GG2A 2GZ5A 2V3YA 1QXYA 1B6AA 2BWSA 3IG4A 4IU6A 2P98A 2ADUA 3TB5A 2DFIA 4IKSA 4IF7A 4RZYA 2V6CA 2BWWA 1R5GA 5FCFA 5CE6A 3PKEA 4KM3A 1BOAA 2BHBA 2GG3A 2BHDA 2BWTA 4U76A 4S2TP 1C23A 5CLSA 2BB7A 5CDEA 2EVCA 2GA2A 3IU7A 3RORA 3TAVA 3IU9A 4FLJA 4U6JA 5JI6A 2BWUA 3CB6A 3MATA 1WBQA 1A16A 3Q6DA 4U6EA 4U6WA 1WLRA 5CNXA 3CTZA 5JFRA 1C24A 4ZWUA 3CB5A 3D27A 1YVMA 1C22A 4U71A 2EA2A 2GU5A 2P9AA 2IW2A 2B3HA 4IDYA 3PKDA 1R5HA 2B3LA 4U69A 4FLIA 1WL6A 1WL9A 2Q92A 3IU8A 3S6BA 5CDLA 2OAZA 4U70A 4FUKA 4FLLA 2GGBA 2BWXA 1N51A 4ZWOA 1YJ3A 2GG0A
chains in the Genus database with same CATH topology
2P99A 4IECA 5D6EA 4IPAA 2GG7A 1YW8A 2G6PA 2EA4A 4A6WA 1W2MA 2Q93A 1C27A 4IKUA 4U6ZA 1QXWA 2V3ZA 4HXXA 5E5BA 4S00A 4U73A 4FLKA 4ZNGA 2NQ7A 3RVAA 2ZSGA 4OOKA 3BITA 3L24A 4R60A 2GU7A 1Y1NA 4S01A 2EVOA 1QZYA 1YW7A 1M35A 3FMQA 1XGSA 2B3KA 4RGZ1 1KP0A 1JAWA 5FCHA 2MATA 3FMRA 1QXZA 2BN7A 1O0XA 3PKAA 2Q96A 4FO8A 4EGEA 2GGCA 2OKNA 1CHMA 4PV4A 4IKRA 4FKCA 4MATA 1BN5A 1XNZA 2GG5A 1KQ9A 4A6VA 5CDVA 4PNCA 2BHCA 3MR1A 5CIKA 2EVMA 2GG9A 4IKTA 3PKCA 5D6FA 2Q95A 4U6CA 5JHUA 3BIPA 4FO7A 4S2RP 2Q8KA 2GU4A 4JUQA 3FM3A 2BH3A 1XGOA 2GTXA 1C21A 1R58A 1MATA 2BWYA 1XGMA 1WY2A 1KQ0A 2GU6A 1YW9A 1B59A 2BWVA 2V3XA 1WN1A 1WKMA 2BHAA 2GG8A 4B28A 4QR8A 3L7GA 1XGNA 4RZZA 2NQ6A 4ZWPA 2HOWA 1PV9A 1W7VA 4U75A 4Z7MA 3BIQA 3PKBA 3MX6A 2Q94A 4U1BA 2GG2A 2GZ5A 2V3YA 1QXYA 1B6AA 2BWSA 3IG4A 4IU6A 2P98A 2ADUA 3TB5A 2DFIA 4IKSA 4IF7A 4RZYA 2V6CA 2BWWA 1R5GA 5FCFA 5CE6A 3PKEA 4KM3A 1BOAA 2BHBA 2GG3A 2BHDA 2BWTA 4U76A 4S2TP 1C23A 5CLSA 2BB7A 5CDEA 2EVCA 2GA2A 3IU7A 3RORA 3TAVA 3IU9A 4FLJA 4U6JA 5JI6A 2BWUA 3CB6A 3MATA 1WBQA 1A16A 3Q6DA 4U6EA 4U6WA 1WLRA 5CNXA 3CTZA 5JFRA 1C24A 4ZWUA 3CB5A 3D27A 1YVMA 1C22A 4U71A 2EA2A 2GU5A 2P9AA 2IW2A 2B3HA 4IDYA 3PKDA 1R5HA 2B3LA 4U69A 4FLIA 1WL6A 1WL9A 2Q92A 3IU8A 3S6BA 5CDLA 2OAZA 4U70A 4FUKA 4FLLA 2GGBA 2BWXA 1N51A 4ZWOA 1YJ3A 2GG0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P99 A;  4IEC A;  5D6E A;  4IPA A;  2GG7 A;  1YW8 A;  2G6P A;  2EA4 A;  4A6W A;  1W2M A;  2Q93 A;  1C27 A;  4IKU A;  4U6Z A;  1QXW A;  2V3Z A;  4HXX A;  5E5B A;  4S00 A;  4U73 A;  4FLK A;  4ZNG A;  2NQ7 A;  3RVA A;  2ZSG A;  4OOK A;  3BIT A;  3L24 A;  4R60 A;  2GU7 A;  1Y1N A;  4S01 A;  2EVO A;  1QZY A;  1YW7 A;  1M35 A;  3FMQ A;  1XGS A;  2B3K A;  4RGZ 1;  1KP0 A;  1JAW A;  5FCH A;  2MAT A;  3FMR A;  1QXZ A;  2BN7 A;  1O0X A;  3PKA A;  2Q96 A;  4FO8 A;  4EGE A;  2GGC A;  2OKN A;  1CHM A;  4PV4 A;  4IKR A;  4FKC A;  4MAT A;  1BN5 A;  1XNZ A;  2GG5 A;  1KQ9 A;  4A6V A;  5CDV A;  4PNC A;  2BHC A;  3MR1 A;  5CIK A;  2EVM A;  2GG9 A;  4IKT A;  3PKC A;  5D6F A;  2Q95 A;  4U6C A;  5JHU A;  3BIP A;  4FO7 A;  4S2R P;  2Q8K A;  2GU4 A;  4JUQ A;  3FM3 A;  2BH3 A;  1XGO A;  2GTX A;  1C21 A;  1R58 A;  1MAT A;  2BWY A;  1XGM A;  1WY2 A;  1KQ0 A;  2GU6 A;  1YW9 A;  1B59 A;  2BWV A;  2V3X A;  1WN1 A;  1WKM A;  2BHA A;  2GG8 A;  4B28 A;  4QR8 A;  3L7G A;  1XGN A;  4RZZ A;  2NQ6 A;  4ZWP A;  2HOW A;  1PV9 A;  1W7V A;  4U75 A;  4Z7M A;  3BIQ A;  3PKB A;  3MX6 A;  2Q94 A;  4U1B A;  2GG2 A;  2GZ5 A;  2V3Y A;  1QXY A;  1B6A A;  2BWS A;  3IG4 A;  4IU6 A;  2P98 A;  2ADU A;  3TB5 A;  2DFI A;  4IKS A;  4IF7 A;  4RZY A;  2V6C A;  2BWW A;  1R5G A;  5FCF A;  5CE6 A;  3PKE A;  4KM3 A;  1BOA A;  2BHB A;  2GG3 A;  2BHD A;  2BWT A;  4U76 A;  4S2T P;  1C23 A;  5CLS A;  2BB7 A;  5CDE A;  2EVC A;  2GA2 A;  3IU7 A;  3ROR A;  3TAV A;  3IU9 A;  4FLJ A;  4U6J A;  5JI6 A;  2BWU A;  3CB6 A;  3MAT A;  1WBQ A;  1A16 A;  3Q6D A;  4U6E A;  4U6W A;  1WLR A;  5CNX A;  3CTZ A;  5JFR A;  1C24 A;  4ZWU A;  3CB5 A;  3D27 A;  1YVM A;  1C22 A;  4U71 A;  2EA2 A;  2GU5 A;  2P9A A;  2IW2 A;  2B3H A;  4IDY A;  3PKD A;  1R5H A;  2B3L A;  4U69 A;  4FLI A;  1WL6 A;  1WL9 A;  2Q92 A;  3IU8 A;  3S6B A;  5CDL A;  2OAZ A;  4U70 A;  4FUK A;  4FLL A;  2GGB A;  2BWX A;  1N51 A;  4ZWO A;  1YJ3 A;  2GG0 A; 
#chains in the Genus database with same CATH topology
 2P99 A;  4IEC A;  5D6E A;  4IPA A;  2GG7 A;  1YW8 A;  2G6P A;  2EA4 A;  4A6W A;  1W2M A;  2Q93 A;  1C27 A;  4IKU A;  4U6Z A;  1QXW A;  2V3Z A;  4HXX A;  5E5B A;  4S00 A;  4U73 A;  4FLK A;  4ZNG A;  2NQ7 A;  3RVA A;  2ZSG A;  4OOK A;  3BIT A;  3L24 A;  4R60 A;  2GU7 A;  1Y1N A;  4S01 A;  2EVO A;  1QZY A;  1YW7 A;  1M35 A;  3FMQ A;  1XGS A;  2B3K A;  4RGZ 1;  1KP0 A;  1JAW A;  5FCH A;  2MAT A;  3FMR A;  1QXZ A;  2BN7 A;  1O0X A;  3PKA A;  2Q96 A;  4FO8 A;  4EGE A;  2GGC A;  2OKN A;  1CHM A;  4PV4 A;  4IKR A;  4FKC A;  4MAT A;  1BN5 A;  1XNZ A;  2GG5 A;  1KQ9 A;  4A6V A;  5CDV A;  4PNC A;  2BHC A;  3MR1 A;  5CIK A;  2EVM A;  2GG9 A;  4IKT A;  3PKC A;  5D6F A;  2Q95 A;  4U6C A;  5JHU A;  3BIP A;  4FO7 A;  4S2R P;  2Q8K A;  2GU4 A;  4JUQ A;  3FM3 A;  2BH3 A;  1XGO A;  2GTX A;  1C21 A;  1R58 A;  1MAT A;  2BWY A;  1XGM A;  1WY2 A;  1KQ0 A;  2GU6 A;  1YW9 A;  1B59 A;  2BWV A;  2V3X A;  1WN1 A;  1WKM A;  2BHA A;  2GG8 A;  4B28 A;  4QR8 A;  3L7G A;  1XGN A;  4RZZ A;  2NQ6 A;  4ZWP A;  2HOW A;  1PV9 A;  1W7V A;  4U75 A;  4Z7M A;  3BIQ A;  3PKB A;  3MX6 A;  2Q94 A;  4U1B A;  2GG2 A;  2GZ5 A;  2V3Y A;  1QXY A;  1B6A A;  2BWS A;  3IG4 A;  4IU6 A;  2P98 A;  2ADU A;  3TB5 A;  2DFI A;  4IKS A;  4IF7 A;  4RZY A;  2V6C A;  2BWW A;  1R5G A;  5FCF A;  5CE6 A;  3PKE A;  4KM3 A;  1BOA A;  2BHB A;  2GG3 A;  2BHD A;  2BWT A;  4U76 A;  4S2T P;  1C23 A;  5CLS A;  2BB7 A;  5CDE A;  2EVC A;  2GA2 A;  3IU7 A;  3ROR A;  3TAV A;  3IU9 A;  4FLJ A;  4U6J A;  5JI6 A;  2BWU A;  3CB6 A;  3MAT A;  1WBQ A;  1A16 A;  3Q6D A;  4U6E A;  4U6W A;  1WLR A;  5CNX A;  3CTZ A;  5JFR A;  1C24 A;  4ZWU A;  3CB5 A;  3D27 A;  1YVM A;  1C22 A;  4U71 A;  2EA2 A;  2GU5 A;  2P9A A;  2IW2 A;  2B3H A;  4IDY A;  3PKD A;  1R5H A;  2B3L A;  4U69 A;  4FLI A;  1WL6 A;  1WL9 A;  2Q92 A;  3IU8 A;  3S6B A;  5CDL A;  2OAZ A;  4U70 A;  4FUK A;  4FLL A;  2GGB A;  2BWX A;  1N51 A;  4ZWO A;  1YJ3 A;  2GG0 A; 
#chains in the Genus database with same CATH homology
 2P99 A;  4IEC A;  5D6E A;  4IPA A;  2GG7 A;  1YW8 A;  2G6P A;  2EA4 A;  4A6W A;  1W2M A;  2Q93 A;  1C27 A;  4IKU A;  4U6Z A;  1QXW A;  2V3Z A;  4HXX A;  5E5B A;  4S00 A;  4U73 A;  4FLK A;  4ZNG A;  2NQ7 A;  3RVA A;  2ZSG A;  4OOK A;  3BIT A;  3L24 A;  4R60 A;  2GU7 A;  1Y1N A;  4S01 A;  2EVO A;  1QZY A;  1YW7 A;  1M35 A;  3FMQ A;  1XGS A;  2B3K A;  4RGZ 1;  1KP0 A;  1JAW A;  5FCH A;  2MAT A;  3FMR A;  1QXZ A;  2BN7 A;  1O0X A;  3PKA A;  2Q96 A;  4FO8 A;  4EGE A;  2GGC A;  2OKN A;  1CHM A;  4PV4 A;  4IKR A;  4FKC A;  4MAT A;  1BN5 A;  1XNZ A;  2GG5 A;  1KQ9 A;  4A6V A;  5CDV A;  4PNC A;  2BHC A;  3MR1 A;  5CIK A;  2EVM A;  2GG9 A;  4IKT A;  3PKC A;  5D6F A;  2Q95 A;  4U6C A;  5JHU A;  3BIP A;  4FO7 A;  4S2R P;  2Q8K A;  2GU4 A;  4JUQ A;  3FM3 A;  2BH3 A;  1XGO A;  2GTX A;  1C21 A;  1R58 A;  1MAT A;  2BWY A;  1XGM A;  1WY2 A;  1KQ0 A;  2GU6 A;  1YW9 A;  1B59 A;  2BWV A;  2V3X A;  1WN1 A;  1WKM A;  2BHA A;  2GG8 A;  4B28 A;  4QR8 A;  3L7G A;  1XGN A;  4RZZ A;  2NQ6 A;  4ZWP A;  2HOW A;  1PV9 A;  1W7V A;  4U75 A;  4Z7M A;  3BIQ A;  3PKB A;  3MX6 A;  2Q94 A;  4U1B A;  2GG2 A;  2GZ5 A;  2V3Y A;  1QXY A;  1B6A A;  2BWS A;  3IG4 A;  4IU6 A;  2P98 A;  2ADU A;  3TB5 A;  2DFI A;  4IKS A;  4IF7 A;  4RZY A;  2V6C A;  2BWW A;  1R5G A;  5FCF A;  5CE6 A;  3PKE A;  4KM3 A;  1BOA A;  2BHB A;  2GG3 A;  2BHD A;  2BWT A;  4U76 A;  4S2T P;  1C23 A;  5CLS A;  2BB7 A;  5CDE A;  2EVC A;  2GA2 A;  3IU7 A;  3ROR A;  3TAV A;  3IU9 A;  4FLJ A;  4U6J A;  5JI6 A;  2BWU A;  3CB6 A;  3MAT A;  1WBQ A;  1A16 A;  3Q6D A;  4U6E A;  4U6W A;  1WLR A;  5CNX A;  3CTZ A;  5JFR A;  1C24 A;  4ZWU A;  3CB5 A;  3D27 A;  1YVM A;  1C22 A;  4U71 A;  2EA2 A;  2GU5 A;  2P9A A;  2IW2 A;  2B3H A;  4IDY A;  3PKD A;  1R5H A;  2B3L A;  4U69 A;  4FLI A;  1WL6 A;  1WL9 A;  2Q92 A;  3IU8 A;  3S6B A;  5CDL A;  2OAZ A;  4U70 A;  4FUK A;  4FLL A;  2GGB A;  2BWX A;  1N51 A;  4ZWO A;  1YJ3 A;  2GG0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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