3PKAA

M. tuberculosis metap with bengamide analog y02, in mn form
Total Genus 87
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkaA01
3FMRA 3PKCA 2BHAA 4R60A 2BWWA 5E5BA 3CB6A 3L7GA 2P99A 2Q96A 4IDYA 4QR8A 4PNCA 1WN1A 4FLLA 4RZYA 2HOWA 2EA4A 1C21A 1C24A 2V3ZA 4ZWOA 2BWTA 1QXWA 3IG4A 1YW9A 2GU5A 2EA2A 1B59A 1BN5A 1CHMA 1WL9A 1C27A 1XGMA 1MATA 5D6FA 1YVMA 4IECA 4FO8A 2GG3A 4FLKA 4IKSA 3RORA 2IW2A 3RVAA 4U75A 3FM3A 4IPAA 1R58A 4IKRA 4U6EA 1YJ3A 2GG5A 4OOKA 2OAZA 1C23A 3PKAA 2ZSGA 2Q95A 3PKDA 2BHDA 2GZ5A 2BWYA 4RGZ1 5CDLA 2B3HA 2GG8A 2BHCA 1W2MA 2Q94A 4FO7A 4U6ZA 5D6EA 2ADUA 4IU6A 4U76A 1XGSA 1WL6A 3BITA 3CB5A 1A16A 3BIPA 2P9AA 2Q92A 4U6WA 5FCHA 1BOAA 2BHBA 5CNXA 3IU8A 1WLRA 4EGEA 2V3YA 3CTZA 2NQ6A 4S2TP 3PKBA 2BN7A 4A6VA 4B28A 4S2RP 2Q8KA 2Q93A 4IF7A 4MATA 4U69A 1C22A 1XGNA 4FKCA 2P98A 2G6PA 1KP0A 1W7VA 2BWUA 3TAVA 4IKTA 2V3XA 2GGBA 2EVCA 5JFRA 5JI6A 4FLIA 1YW7A 1YW8A 3IU9A 4S01A 4U6JA 3MX6A 5CDEA 5CDVA 2B3LA 2GGCA 2GU7A 2BH3A 4PV4A 2EVOA 2OKNA 3FMQA 2B3KA 2DFIA 5JHUA 2NQ7A 4FLJA 3IU7A 4Z7MA 1PV9A 3BIQA 3TB5A 4U1BA 1M35A 1XGOA 4KM3A 4ZWUA 2MATA 3L24A 1JAWA 2GG9A 1QXZA 3MR1A 4FUKA 2BWXA 4S00A 1R5HA 4U71A 2BB7A 2EVMA 2GG0A 1WBQA 5CE6A 2V6CA 1XNZA 1QXYA 3PKEA 1N51A 2GU4A 5CLSA 3MATA 2GA2A 1KQ9A 5FCFA 1WY2A 2GTXA 4HXXA 4U73A 4ZNGA 4IKUA 2BWVA 3S6BA 4RZZA 1Y1NA 5CIKA 2GG2A 4ZWPA 2GG7A 3Q6DA 2BWSA 2GU6A 4U70A 1KQ0A 1WKMA 4U6CA 4A6WA 3D27A 1O0XA 4JUQA 1R5GA 1B6AA 1QZYA
chains in the Genus database with same CATH superfamily
3FMRA 3PKCA 2BHAA 4R60A 2BWWA 5E5BA 3CB6A 3L7GA 2P99A 2Q96A 4IDYA 4QR8A 4PNCA 1WN1A 4FLLA 4RZYA 2HOWA 2EA4A 1C21A 1C24A 2V3ZA 4ZWOA 2BWTA 1QXWA 3IG4A 1YW9A 2GU5A 2EA2A 1B59A 1BN5A 1CHMA 1WL9A 1C27A 1XGMA 1MATA 5D6FA 1YVMA 4IECA 4FO8A 2GG3A 4FLKA 4IKSA 3RORA 2IW2A 3RVAA 4U75A 3FM3A 4IPAA 1R58A 4IKRA 4U6EA 1YJ3A 2GG5A 4OOKA 2OAZA 1C23A 3PKAA 2ZSGA 2Q95A 3PKDA 2BHDA 2GZ5A 2BWYA 4RGZ1 5CDLA 2B3HA 2GG8A 2BHCA 1W2MA 2Q94A 4FO7A 4U6ZA 5D6EA 2ADUA 4IU6A 4U76A 1XGSA 1WL6A 3BITA 3CB5A 1A16A 3BIPA 2P9AA 2Q92A 4U6WA 5FCHA 1BOAA 2BHBA 5CNXA 3IU8A 1WLRA 4EGEA 2V3YA 3CTZA 2NQ6A 4S2TP 3PKBA 2BN7A 4A6VA 4B28A 4S2RP 2Q8KA 2Q93A 4IF7A 4MATA 4U69A 1C22A 1XGNA 4FKCA 2P98A 2G6PA 1KP0A 1W7VA 2BWUA 3TAVA 4IKTA 2V3XA 2GGBA 2EVCA 5JFRA 5JI6A 4FLIA 1YW7A 1YW8A 3IU9A 4S01A 4U6JA 3MX6A 5CDEA 5CDVA 2B3LA 2GGCA 2GU7A 2BH3A 4PV4A 2EVOA 2OKNA 3FMQA 2B3KA 2DFIA 5JHUA 2NQ7A 4FLJA 3IU7A 4Z7MA 1PV9A 3BIQA 3TB5A 4U1BA 1M35A 1XGOA 4KM3A 4ZWUA 2MATA 3L24A 1JAWA 2GG9A 1QXZA 3MR1A 4FUKA 2BWXA 4S00A 1R5HA 4U71A 2BB7A 2EVMA 2GG0A 1WBQA 5CE6A 2V6CA 1XNZA 1QXYA 3PKEA 1N51A 2GU4A 5CLSA 3MATA 2GA2A 1KQ9A 5FCFA 1WY2A 2GTXA 4HXXA 4U73A 4ZNGA 4IKUA 2BWVA 3S6BA 4RZZA 1Y1NA 5CIKA 2GG2A 4ZWPA 2GG7A 3Q6DA 2BWSA 2GU6A 4U70A 1KQ0A 1WKMA 4U6CA 4A6WA 3D27A 1O0XA 4JUQA 1R5GA 1B6AA 1QZYA
chains in the Genus database with same CATH topology
3FMRA 3PKCA 2BHAA 4R60A 2BWWA 5E5BA 3CB6A 3L7GA 2P99A 2Q96A 4IDYA 4QR8A 4PNCA 1WN1A 4FLLA 4RZYA 2HOWA 2EA4A 1C21A 1C24A 2V3ZA 4ZWOA 2BWTA 1QXWA 3IG4A 1YW9A 2GU5A 2EA2A 1B59A 1BN5A 1CHMA 1WL9A 1C27A 1XGMA 1MATA 5D6FA 1YVMA 4IECA 4FO8A 2GG3A 4FLKA 4IKSA 3RORA 2IW2A 3RVAA 4U75A 3FM3A 4IPAA 1R58A 4IKRA 4U6EA 1YJ3A 2GG5A 4OOKA 2OAZA 1C23A 3PKAA 2ZSGA 2Q95A 3PKDA 2BHDA 2GZ5A 2BWYA 4RGZ1 5CDLA 2B3HA 2GG8A 2BHCA 1W2MA 2Q94A 4FO7A 4U6ZA 5D6EA 2ADUA 4IU6A 4U76A 1XGSA 1WL6A 3BITA 3CB5A 1A16A 3BIPA 2P9AA 2Q92A 4U6WA 5FCHA 1BOAA 2BHBA 5CNXA 3IU8A 1WLRA 4EGEA 2V3YA 3CTZA 2NQ6A 4S2TP 3PKBA 2BN7A 4A6VA 4B28A 4S2RP 2Q8KA 2Q93A 4IF7A 4MATA 4U69A 1C22A 1XGNA 4FKCA 2P98A 2G6PA 1KP0A 1W7VA 2BWUA 3TAVA 4IKTA 2V3XA 2GGBA 2EVCA 5JFRA 5JI6A 4FLIA 1YW7A 1YW8A 3IU9A 4S01A 4U6JA 3MX6A 5CDEA 5CDVA 2B3LA 2GGCA 2GU7A 2BH3A 4PV4A 2EVOA 2OKNA 3FMQA 2B3KA 2DFIA 5JHUA 2NQ7A 4FLJA 3IU7A 4Z7MA 1PV9A 3BIQA 3TB5A 4U1BA 1M35A 1XGOA 4KM3A 4ZWUA 2MATA 3L24A 1JAWA 2GG9A 1QXZA 3MR1A 4FUKA 2BWXA 4S00A 1R5HA 4U71A 2BB7A 2EVMA 2GG0A 1WBQA 5CE6A 2V6CA 1XNZA 1QXYA 3PKEA 1N51A 2GU4A 5CLSA 3MATA 2GA2A 1KQ9A 5FCFA 1WY2A 2GTXA 4HXXA 4U73A 4ZNGA 4IKUA 2BWVA 3S6BA 4RZZA 1Y1NA 5CIKA 2GG2A 4ZWPA 2GG7A 3Q6DA 2BWSA 2GU6A 4U70A 1KQ0A 1WKMA 4U6CA 4A6WA 3D27A 1O0XA 4JUQA 1R5GA 1B6AA 1QZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FMR A;  3PKC A;  2BHA A;  4R60 A;  2BWW A;  5E5B A;  3CB6 A;  3L7G A;  2P99 A;  2Q96 A;  4IDY A;  4QR8 A;  4PNC A;  1WN1 A;  4FLL A;  4RZY A;  2HOW A;  2EA4 A;  1C21 A;  1C24 A;  2V3Z A;  4ZWO A;  2BWT A;  1QXW A;  3IG4 A;  1YW9 A;  2GU5 A;  2EA2 A;  1B59 A;  1BN5 A;  1CHM A;  1WL9 A;  1C27 A;  1XGM A;  1MAT A;  5D6F A;  1YVM A;  4IEC A;  4FO8 A;  2GG3 A;  4FLK A;  4IKS A;  3ROR A;  2IW2 A;  3RVA A;  4U75 A;  3FM3 A;  4IPA A;  1R58 A;  4IKR A;  4U6E A;  1YJ3 A;  2GG5 A;  4OOK A;  2OAZ A;  1C23 A;  3PKA A;  2ZSG A;  2Q95 A;  3PKD A;  2BHD A;  2GZ5 A;  2BWY A;  4RGZ 1;  5CDL A;  2B3H A;  2GG8 A;  2BHC A;  1W2M A;  2Q94 A;  4FO7 A;  4U6Z A;  5D6E A;  2ADU A;  4IU6 A;  4U76 A;  1XGS A;  1WL6 A;  3BIT A;  3CB5 A;  1A16 A;  3BIP A;  2P9A A;  2Q92 A;  4U6W A;  5FCH A;  1BOA A;  2BHB A;  5CNX A;  3IU8 A;  1WLR A;  4EGE A;  2V3Y A;  3CTZ A;  2NQ6 A;  4S2T P;  3PKB A;  2BN7 A;  4A6V A;  4B28 A;  4S2R P;  2Q8K A;  2Q93 A;  4IF7 A;  4MAT A;  4U69 A;  1C22 A;  1XGN A;  4FKC A;  2P98 A;  2G6P A;  1KP0 A;  1W7V A;  2BWU A;  3TAV A;  4IKT A;  2V3X A;  2GGB A;  2EVC A;  5JFR A;  5JI6 A;  4FLI A;  1YW7 A;  1YW8 A;  3IU9 A;  4S01 A;  4U6J A;  3MX6 A;  5CDE A;  5CDV A;  2B3L A;  2GGC A;  2GU7 A;  2BH3 A;  4PV4 A;  2EVO A;  2OKN A;  3FMQ A;  2B3K A;  2DFI A;  5JHU A;  2NQ7 A;  4FLJ A;  3IU7 A;  4Z7M A;  1PV9 A;  3BIQ A;  3TB5 A;  4U1B A;  1M35 A;  1XGO A;  4KM3 A;  4ZWU A;  2MAT A;  3L24 A;  1JAW A;  2GG9 A;  1QXZ A;  3MR1 A;  4FUK A;  2BWX A;  4S00 A;  1R5H A;  4U71 A;  2BB7 A;  2EVM A;  2GG0 A;  1WBQ A;  5CE6 A;  2V6C A;  1XNZ A;  1QXY A;  3PKE A;  1N51 A;  2GU4 A;  5CLS A;  3MAT A;  2GA2 A;  1KQ9 A;  5FCF A;  1WY2 A;  2GTX A;  4HXX A;  4U73 A;  4ZNG A;  4IKU A;  2BWV A;  3S6B A;  4RZZ A;  1Y1N A;  5CIK A;  2GG2 A;  4ZWP A;  2GG7 A;  3Q6D A;  2BWS A;  2GU6 A;  4U70 A;  1KQ0 A;  1WKM A;  4U6C A;  4A6W A;  3D27 A;  1O0X A;  4JUQ A;  1R5G A;  1B6A A;  1QZY A; 
#chains in the Genus database with same CATH topology
 3FMR A;  3PKC A;  2BHA A;  4R60 A;  2BWW A;  5E5B A;  3CB6 A;  3L7G A;  2P99 A;  2Q96 A;  4IDY A;  4QR8 A;  4PNC A;  1WN1 A;  4FLL A;  4RZY A;  2HOW A;  2EA4 A;  1C21 A;  1C24 A;  2V3Z A;  4ZWO A;  2BWT A;  1QXW A;  3IG4 A;  1YW9 A;  2GU5 A;  2EA2 A;  1B59 A;  1BN5 A;  1CHM A;  1WL9 A;  1C27 A;  1XGM A;  1MAT A;  5D6F A;  1YVM A;  4IEC A;  4FO8 A;  2GG3 A;  4FLK A;  4IKS A;  3ROR A;  2IW2 A;  3RVA A;  4U75 A;  3FM3 A;  4IPA A;  1R58 A;  4IKR A;  4U6E A;  1YJ3 A;  2GG5 A;  4OOK A;  2OAZ A;  1C23 A;  3PKA A;  2ZSG A;  2Q95 A;  3PKD A;  2BHD A;  2GZ5 A;  2BWY A;  4RGZ 1;  5CDL A;  2B3H A;  2GG8 A;  2BHC A;  1W2M A;  2Q94 A;  4FO7 A;  4U6Z A;  5D6E A;  2ADU A;  4IU6 A;  4U76 A;  1XGS A;  1WL6 A;  3BIT A;  3CB5 A;  1A16 A;  3BIP A;  2P9A A;  2Q92 A;  4U6W A;  5FCH A;  1BOA A;  2BHB A;  5CNX A;  3IU8 A;  1WLR A;  4EGE A;  2V3Y A;  3CTZ A;  2NQ6 A;  4S2T P;  3PKB A;  2BN7 A;  4A6V A;  4B28 A;  4S2R P;  2Q8K A;  2Q93 A;  4IF7 A;  4MAT A;  4U69 A;  1C22 A;  1XGN A;  4FKC A;  2P98 A;  2G6P A;  1KP0 A;  1W7V A;  2BWU A;  3TAV A;  4IKT A;  2V3X A;  2GGB A;  2EVC A;  5JFR A;  5JI6 A;  4FLI A;  1YW7 A;  1YW8 A;  3IU9 A;  4S01 A;  4U6J A;  3MX6 A;  5CDE A;  5CDV A;  2B3L A;  2GGC A;  2GU7 A;  2BH3 A;  4PV4 A;  2EVO A;  2OKN A;  3FMQ A;  2B3K A;  2DFI A;  5JHU A;  2NQ7 A;  4FLJ A;  3IU7 A;  4Z7M A;  1PV9 A;  3BIQ A;  3TB5 A;  4U1B A;  1M35 A;  1XGO A;  4KM3 A;  4ZWU A;  2MAT A;  3L24 A;  1JAW A;  2GG9 A;  1QXZ A;  3MR1 A;  4FUK A;  2BWX A;  4S00 A;  1R5H A;  4U71 A;  2BB7 A;  2EVM A;  2GG0 A;  1WBQ A;  5CE6 A;  2V6C A;  1XNZ A;  1QXY A;  3PKE A;  1N51 A;  2GU4 A;  5CLS A;  3MAT A;  2GA2 A;  1KQ9 A;  5FCF A;  1WY2 A;  2GTX A;  4HXX A;  4U73 A;  4ZNG A;  4IKU A;  2BWV A;  3S6B A;  4RZZ A;  1Y1N A;  5CIK A;  2GG2 A;  4ZWP A;  2GG7 A;  3Q6D A;  2BWS A;  2GU6 A;  4U70 A;  1KQ0 A;  1WKM A;  4U6C A;  4A6W A;  3D27 A;  1O0X A;  4JUQ A;  1R5G A;  1B6A A;  1QZY A; 
#chains in the Genus database with same CATH homology
 3FMR A;  3PKC A;  2BHA A;  4R60 A;  2BWW A;  5E5B A;  3CB6 A;  3L7G A;  2P99 A;  2Q96 A;  4IDY A;  4QR8 A;  4PNC A;  1WN1 A;  4FLL A;  4RZY A;  2HOW A;  2EA4 A;  1C21 A;  1C24 A;  2V3Z A;  4ZWO A;  2BWT A;  1QXW A;  3IG4 A;  1YW9 A;  2GU5 A;  2EA2 A;  1B59 A;  1BN5 A;  1CHM A;  1WL9 A;  1C27 A;  1XGM A;  1MAT A;  5D6F A;  1YVM A;  4IEC A;  4FO8 A;  2GG3 A;  4FLK A;  4IKS A;  3ROR A;  2IW2 A;  3RVA A;  4U75 A;  3FM3 A;  4IPA A;  1R58 A;  4IKR A;  4U6E A;  1YJ3 A;  2GG5 A;  4OOK A;  2OAZ A;  1C23 A;  3PKA A;  2ZSG A;  2Q95 A;  3PKD A;  2BHD A;  2GZ5 A;  2BWY A;  4RGZ 1;  5CDL A;  2B3H A;  2GG8 A;  2BHC A;  1W2M A;  2Q94 A;  4FO7 A;  4U6Z A;  5D6E A;  2ADU A;  4IU6 A;  4U76 A;  1XGS A;  1WL6 A;  3BIT A;  3CB5 A;  1A16 A;  3BIP A;  2P9A A;  2Q92 A;  4U6W A;  5FCH A;  1BOA A;  2BHB A;  5CNX A;  3IU8 A;  1WLR A;  4EGE A;  2V3Y A;  3CTZ A;  2NQ6 A;  4S2T P;  3PKB A;  2BN7 A;  4A6V A;  4B28 A;  4S2R P;  2Q8K A;  2Q93 A;  4IF7 A;  4MAT A;  4U69 A;  1C22 A;  1XGN A;  4FKC A;  2P98 A;  2G6P A;  1KP0 A;  1W7V A;  2BWU A;  3TAV A;  4IKT A;  2V3X A;  2GGB A;  2EVC A;  5JFR A;  5JI6 A;  4FLI A;  1YW7 A;  1YW8 A;  3IU9 A;  4S01 A;  4U6J A;  3MX6 A;  5CDE A;  5CDV A;  2B3L A;  2GGC A;  2GU7 A;  2BH3 A;  4PV4 A;  2EVO A;  2OKN A;  3FMQ A;  2B3K A;  2DFI A;  5JHU A;  2NQ7 A;  4FLJ A;  3IU7 A;  4Z7M A;  1PV9 A;  3BIQ A;  3TB5 A;  4U1B A;  1M35 A;  1XGO A;  4KM3 A;  4ZWU A;  2MAT A;  3L24 A;  1JAW A;  2GG9 A;  1QXZ A;  3MR1 A;  4FUK A;  2BWX A;  4S00 A;  1R5H A;  4U71 A;  2BB7 A;  2EVM A;  2GG0 A;  1WBQ A;  5CE6 A;  2V6C A;  1XNZ A;  1QXY A;  3PKE A;  1N51 A;  2GU4 A;  5CLS A;  3MAT A;  2GA2 A;  1KQ9 A;  5FCF A;  1WY2 A;  2GTX A;  4HXX A;  4U73 A;  4ZNG A;  4IKU A;  2BWV A;  3S6B A;  4RZZ A;  1Y1N A;  5CIK A;  2GG2 A;  4ZWP A;  2GG7 A;  3Q6D A;  2BWS A;  2GU6 A;  4U70 A;  1KQ0 A;  1WKM A;  4U6C A;  4A6W A;  3D27 A;  1O0X A;  4JUQ A;  1R5G A;  1B6A A;  1QZY A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...