3PKAA

M. tuberculosis metap with bengamide analog y02, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkaA01
3BITA 2GG3A 1O0XA 4U70A 2NQ7A 2P9AA 3D27A 2Q94A 1YW8A 2GG2A 5JHUA 2GA2A 3TB5A 3IU8A 3L24A 4IDYA 2BN7A 1XGMA 2BH3A 5CDVA 4ZWUA 4S2RP 3PKEA 1C21A 4EGEA 1WY2A 3RORA 4IKRA 2GU6A 2BWXA 1KP0A 1W7VA 2OAZA 4OOKA 4S00A 3FMQA 4U6WA 1WKMA 4B28A 5CDLA 1BN5A 1QXZA 2V3XA 4QR8A 4U6JA 1C24A 4ZNGA 1WBQA 3PKCA 4FLJA 3CTZA 2V3ZA 2GG8A 4A6VA 1KQ0A 1Y1NA 2IW2A 2P99A 2B3HA 4IPAA 1YW7A 2BWVA 2BWWA 1QZYA 2BWUA 2Q8KA 4A6WA 2GG7A 2GTXA 4FLIA 1WL9A 3PKAA 3S6BA 1YJ3A 4R60A 2P98A 1W2MA 4FLKA 1A16A 5JI6A 4IECA 4ZWOA 4Z7MA 1WLRA 4PNCA 4HXXA 4FKCA 4FUKA 1YVMA 4U73A 5D6EA 3IU9A 5CIKA 1WN1A 2BHBA 1YW9A 4IKUA 5FCHA 2GU4A 2GG5A 4FLLA 4FO8A 1MATA 4IKSA 4U6EA 1R5GA 3MX6A 1B6AA 4RZZA 4U69A 1XNZA 1KQ9A 4IU6A 4IKTA 3PKDA 2GU7A 2EVOA 3Q6DA 1B59A 4U6CA 4S01A 3PKBA 4U6ZA 2EA2A 2Q95A 1JAWA 1QXYA 2EA4A 1C23A 2B3LA 4PV4A 3FM3A 1C22A 5CDEA 1CHMA 5JFRA 3L7GA 4MATA 2EVCA 4IF7A 2GGBA 2MATA 1XGSA 1XGOA 3CB5A 2OKNA 1XGNA 2V3YA 2DFIA 3MR1A 2BWYA 2V6CA 2BHAA 2GGCA 2Q92A 2ZSGA 3RVAA 4RZYA 3IG4A 3BIPA 5CNXA 4RGZ1 3FMRA 4KM3A 2ADUA 2BHCA 2B3KA 2BB7A 2GG9A 3IU7A 2EVMA 5CLSA 4U71A 1WL6A 4JUQA 5CE6A 3TAVA 2Q96A 2GG0A 1M35A 1QXWA 1N51A 4FO7A 4U1BA 2NQ6A 2BWSA 1PV9A 4ZWPA 2HOWA 1R58A 4U76A 3CB6A 4U75A 2BWTA 3BIQA 4S2TP 1C27A 5D6FA 2BHDA 5FCFA 2GU5A 2G6PA 3MATA 5E5BA 1R5HA 2Q93A 2GZ5A 1BOAA
chains in the Genus database with same CATH superfamily
3BITA 2GG3A 1O0XA 4U70A 2NQ7A 2P9AA 3D27A 2Q94A 1YW8A 2GG2A 5JHUA 2GA2A 3TB5A 3IU8A 3L24A 4IDYA 2BN7A 1XGMA 2BH3A 5CDVA 4ZWUA 4S2RP 3PKEA 1C21A 4EGEA 1WY2A 3RORA 4IKRA 2GU6A 2BWXA 1KP0A 1W7VA 2OAZA 4OOKA 4S00A 3FMQA 4U6WA 1WKMA 4B28A 5CDLA 1BN5A 1QXZA 2V3XA 4QR8A 4U6JA 1C24A 4ZNGA 1WBQA 3PKCA 4FLJA 3CTZA 2V3ZA 2GG8A 4A6VA 1KQ0A 1Y1NA 2IW2A 2P99A 2B3HA 4IPAA 1YW7A 2BWVA 2BWWA 1QZYA 2BWUA 2Q8KA 4A6WA 2GG7A 2GTXA 4FLIA 1WL9A 3PKAA 3S6BA 1YJ3A 4R60A 2P98A 1W2MA 4FLKA 1A16A 5JI6A 4IECA 4ZWOA 4Z7MA 1WLRA 4PNCA 4HXXA 4FKCA 4FUKA 1YVMA 4U73A 5D6EA 3IU9A 5CIKA 1WN1A 2BHBA 1YW9A 4IKUA 5FCHA 2GU4A 2GG5A 4FLLA 4FO8A 1MATA 4IKSA 4U6EA 1R5GA 3MX6A 1B6AA 4RZZA 4U69A 1XNZA 1KQ9A 4IU6A 4IKTA 3PKDA 2GU7A 2EVOA 3Q6DA 1B59A 4U6CA 4S01A 3PKBA 4U6ZA 2EA2A 2Q95A 1JAWA 1QXYA 2EA4A 1C23A 2B3LA 4PV4A 3FM3A 1C22A 5CDEA 1CHMA 5JFRA 3L7GA 4MATA 2EVCA 4IF7A 2GGBA 2MATA 1XGSA 1XGOA 3CB5A 2OKNA 1XGNA 2V3YA 2DFIA 3MR1A 2BWYA 2V6CA 2BHAA 2GGCA 2Q92A 2ZSGA 3RVAA 4RZYA 3IG4A 3BIPA 5CNXA 4RGZ1 3FMRA 4KM3A 2ADUA 2BHCA 2B3KA 2BB7A 2GG9A 3IU7A 2EVMA 5CLSA 4U71A 1WL6A 4JUQA 5CE6A 3TAVA 2Q96A 2GG0A 1M35A 1QXWA 1N51A 4FO7A 4U1BA 2NQ6A 2BWSA 1PV9A 4ZWPA 2HOWA 1R58A 4U76A 3CB6A 4U75A 2BWTA 3BIQA 4S2TP 1C27A 5D6FA 2BHDA 5FCFA 2GU5A 2G6PA 3MATA 5E5BA 1R5HA 2Q93A 2GZ5A 1BOAA
chains in the Genus database with same CATH topology
3BITA 2GG3A 1O0XA 4U70A 2NQ7A 2P9AA 3D27A 2Q94A 1YW8A 2GG2A 5JHUA 2GA2A 3TB5A 3IU8A 3L24A 4IDYA 2BN7A 1XGMA 2BH3A 5CDVA 4ZWUA 4S2RP 3PKEA 1C21A 4EGEA 1WY2A 3RORA 4IKRA 2GU6A 2BWXA 1KP0A 1W7VA 2OAZA 4OOKA 4S00A 3FMQA 4U6WA 1WKMA 4B28A 5CDLA 1BN5A 1QXZA 2V3XA 4QR8A 4U6JA 1C24A 4ZNGA 1WBQA 3PKCA 4FLJA 3CTZA 2V3ZA 2GG8A 4A6VA 1KQ0A 1Y1NA 2IW2A 2P99A 2B3HA 4IPAA 1YW7A 2BWVA 2BWWA 1QZYA 2BWUA 2Q8KA 4A6WA 2GG7A 2GTXA 4FLIA 1WL9A 3PKAA 3S6BA 1YJ3A 4R60A 2P98A 1W2MA 4FLKA 1A16A 5JI6A 4IECA 4ZWOA 4Z7MA 1WLRA 4PNCA 4HXXA 4FKCA 4FUKA 1YVMA 4U73A 5D6EA 3IU9A 5CIKA 1WN1A 2BHBA 1YW9A 4IKUA 5FCHA 2GU4A 2GG5A 4FLLA 4FO8A 1MATA 4IKSA 4U6EA 1R5GA 3MX6A 1B6AA 4RZZA 4U69A 1XNZA 1KQ9A 4IU6A 4IKTA 3PKDA 2GU7A 2EVOA 3Q6DA 1B59A 4U6CA 4S01A 3PKBA 4U6ZA 2EA2A 2Q95A 1JAWA 1QXYA 2EA4A 1C23A 2B3LA 4PV4A 3FM3A 1C22A 5CDEA 1CHMA 5JFRA 3L7GA 4MATA 2EVCA 4IF7A 2GGBA 2MATA 1XGSA 1XGOA 3CB5A 2OKNA 1XGNA 2V3YA 2DFIA 3MR1A 2BWYA 2V6CA 2BHAA 2GGCA 2Q92A 2ZSGA 3RVAA 4RZYA 3IG4A 3BIPA 5CNXA 4RGZ1 3FMRA 4KM3A 2ADUA 2BHCA 2B3KA 2BB7A 2GG9A 3IU7A 2EVMA 5CLSA 4U71A 1WL6A 4JUQA 5CE6A 3TAVA 2Q96A 2GG0A 1M35A 1QXWA 1N51A 4FO7A 4U1BA 2NQ6A 2BWSA 1PV9A 4ZWPA 2HOWA 1R58A 4U76A 3CB6A 4U75A 2BWTA 3BIQA 4S2TP 1C27A 5D6FA 2BHDA 5FCFA 2GU5A 2G6PA 3MATA 5E5BA 1R5HA 2Q93A 2GZ5A 1BOAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BIT A;  2GG3 A;  1O0X A;  4U70 A;  2NQ7 A;  2P9A A;  3D27 A;  2Q94 A;  1YW8 A;  2GG2 A;  5JHU A;  2GA2 A;  3TB5 A;  3IU8 A;  3L24 A;  4IDY A;  2BN7 A;  1XGM A;  2BH3 A;  5CDV A;  4ZWU A;  4S2R P;  3PKE A;  1C21 A;  4EGE A;  1WY2 A;  3ROR A;  4IKR A;  2GU6 A;  2BWX A;  1KP0 A;  1W7V A;  2OAZ A;  4OOK A;  4S00 A;  3FMQ A;  4U6W A;  1WKM A;  4B28 A;  5CDL A;  1BN5 A;  1QXZ A;  2V3X A;  4QR8 A;  4U6J A;  1C24 A;  4ZNG A;  1WBQ A;  3PKC A;  4FLJ A;  3CTZ A;  2V3Z A;  2GG8 A;  4A6V A;  1KQ0 A;  1Y1N A;  2IW2 A;  2P99 A;  2B3H A;  4IPA A;  1YW7 A;  2BWV A;  2BWW A;  1QZY A;  2BWU A;  2Q8K A;  4A6W A;  2GG7 A;  2GTX A;  4FLI A;  1WL9 A;  3PKA A;  3S6B A;  1YJ3 A;  4R60 A;  2P98 A;  1W2M A;  4FLK A;  1A16 A;  5JI6 A;  4IEC A;  4ZWO A;  4Z7M A;  1WLR A;  4PNC A;  4HXX A;  4FKC A;  4FUK A;  1YVM A;  4U73 A;  5D6E A;  3IU9 A;  5CIK A;  1WN1 A;  2BHB A;  1YW9 A;  4IKU A;  5FCH A;  2GU4 A;  2GG5 A;  4FLL A;  4FO8 A;  1MAT A;  4IKS A;  4U6E A;  1R5G A;  3MX6 A;  1B6A A;  4RZZ A;  4U69 A;  1XNZ A;  1KQ9 A;  4IU6 A;  4IKT A;  3PKD A;  2GU7 A;  2EVO A;  3Q6D A;  1B59 A;  4U6C A;  4S01 A;  3PKB A;  4U6Z A;  2EA2 A;  2Q95 A;  1JAW A;  1QXY A;  2EA4 A;  1C23 A;  2B3L A;  4PV4 A;  3FM3 A;  1C22 A;  5CDE A;  1CHM A;  5JFR A;  3L7G A;  4MAT A;  2EVC A;  4IF7 A;  2GGB A;  2MAT A;  1XGS A;  1XGO A;  3CB5 A;  2OKN A;  1XGN A;  2V3Y A;  2DFI A;  3MR1 A;  2BWY A;  2V6C A;  2BHA A;  2GGC A;  2Q92 A;  2ZSG A;  3RVA A;  4RZY A;  3IG4 A;  3BIP A;  5CNX A;  4RGZ 1;  3FMR A;  4KM3 A;  2ADU A;  2BHC A;  2B3K A;  2BB7 A;  2GG9 A;  3IU7 A;  2EVM A;  5CLS A;  4U71 A;  1WL6 A;  4JUQ A;  5CE6 A;  3TAV A;  2Q96 A;  2GG0 A;  1M35 A;  1QXW A;  1N51 A;  4FO7 A;  4U1B A;  2NQ6 A;  2BWS A;  1PV9 A;  4ZWP A;  2HOW A;  1R58 A;  4U76 A;  3CB6 A;  4U75 A;  2BWT A;  3BIQ A;  4S2T P;  1C27 A;  5D6F A;  2BHD A;  5FCF A;  2GU5 A;  2G6P A;  3MAT A;  5E5B A;  1R5H A;  2Q93 A;  2GZ5 A;  1BOA A; 
#chains in the Genus database with same CATH topology
 3BIT A;  2GG3 A;  1O0X A;  4U70 A;  2NQ7 A;  2P9A A;  3D27 A;  2Q94 A;  1YW8 A;  2GG2 A;  5JHU A;  2GA2 A;  3TB5 A;  3IU8 A;  3L24 A;  4IDY A;  2BN7 A;  1XGM A;  2BH3 A;  5CDV A;  4ZWU A;  4S2R P;  3PKE A;  1C21 A;  4EGE A;  1WY2 A;  3ROR A;  4IKR A;  2GU6 A;  2BWX A;  1KP0 A;  1W7V A;  2OAZ A;  4OOK A;  4S00 A;  3FMQ A;  4U6W A;  1WKM A;  4B28 A;  5CDL A;  1BN5 A;  1QXZ A;  2V3X A;  4QR8 A;  4U6J A;  1C24 A;  4ZNG A;  1WBQ A;  3PKC A;  4FLJ A;  3CTZ A;  2V3Z A;  2GG8 A;  4A6V A;  1KQ0 A;  1Y1N A;  2IW2 A;  2P99 A;  2B3H A;  4IPA A;  1YW7 A;  2BWV A;  2BWW A;  1QZY A;  2BWU A;  2Q8K A;  4A6W A;  2GG7 A;  2GTX A;  4FLI A;  1WL9 A;  3PKA A;  3S6B A;  1YJ3 A;  4R60 A;  2P98 A;  1W2M A;  4FLK A;  1A16 A;  5JI6 A;  4IEC A;  4ZWO A;  4Z7M A;  1WLR A;  4PNC A;  4HXX A;  4FKC A;  4FUK A;  1YVM A;  4U73 A;  5D6E A;  3IU9 A;  5CIK A;  1WN1 A;  2BHB A;  1YW9 A;  4IKU A;  5FCH A;  2GU4 A;  2GG5 A;  4FLL A;  4FO8 A;  1MAT A;  4IKS A;  4U6E A;  1R5G A;  3MX6 A;  1B6A A;  4RZZ A;  4U69 A;  1XNZ A;  1KQ9 A;  4IU6 A;  4IKT A;  3PKD A;  2GU7 A;  2EVO A;  3Q6D A;  1B59 A;  4U6C A;  4S01 A;  3PKB A;  4U6Z A;  2EA2 A;  2Q95 A;  1JAW A;  1QXY A;  2EA4 A;  1C23 A;  2B3L A;  4PV4 A;  3FM3 A;  1C22 A;  5CDE A;  1CHM A;  5JFR A;  3L7G A;  4MAT A;  2EVC A;  4IF7 A;  2GGB A;  2MAT A;  1XGS A;  1XGO A;  3CB5 A;  2OKN A;  1XGN A;  2V3Y A;  2DFI A;  3MR1 A;  2BWY A;  2V6C A;  2BHA A;  2GGC A;  2Q92 A;  2ZSG A;  3RVA A;  4RZY A;  3IG4 A;  3BIP A;  5CNX A;  4RGZ 1;  3FMR A;  4KM3 A;  2ADU A;  2BHC A;  2B3K A;  2BB7 A;  2GG9 A;  3IU7 A;  2EVM A;  5CLS A;  4U71 A;  1WL6 A;  4JUQ A;  5CE6 A;  3TAV A;  2Q96 A;  2GG0 A;  1M35 A;  1QXW A;  1N51 A;  4FO7 A;  4U1B A;  2NQ6 A;  2BWS A;  1PV9 A;  4ZWP A;  2HOW A;  1R58 A;  4U76 A;  3CB6 A;  4U75 A;  2BWT A;  3BIQ A;  4S2T P;  1C27 A;  5D6F A;  2BHD A;  5FCF A;  2GU5 A;  2G6P A;  3MAT A;  5E5B A;  1R5H A;  2Q93 A;  2GZ5 A;  1BOA A; 
#chains in the Genus database with same CATH homology
 3BIT A;  2GG3 A;  1O0X A;  4U70 A;  2NQ7 A;  2P9A A;  3D27 A;  2Q94 A;  1YW8 A;  2GG2 A;  5JHU A;  2GA2 A;  3TB5 A;  3IU8 A;  3L24 A;  4IDY A;  2BN7 A;  1XGM A;  2BH3 A;  5CDV A;  4ZWU A;  4S2R P;  3PKE A;  1C21 A;  4EGE A;  1WY2 A;  3ROR A;  4IKR A;  2GU6 A;  2BWX A;  1KP0 A;  1W7V A;  2OAZ A;  4OOK A;  4S00 A;  3FMQ A;  4U6W A;  1WKM A;  4B28 A;  5CDL A;  1BN5 A;  1QXZ A;  2V3X A;  4QR8 A;  4U6J A;  1C24 A;  4ZNG A;  1WBQ A;  3PKC A;  4FLJ A;  3CTZ A;  2V3Z A;  2GG8 A;  4A6V A;  1KQ0 A;  1Y1N A;  2IW2 A;  2P99 A;  2B3H A;  4IPA A;  1YW7 A;  2BWV A;  2BWW A;  1QZY A;  2BWU A;  2Q8K A;  4A6W A;  2GG7 A;  2GTX A;  4FLI A;  1WL9 A;  3PKA A;  3S6B A;  1YJ3 A;  4R60 A;  2P98 A;  1W2M A;  4FLK A;  1A16 A;  5JI6 A;  4IEC A;  4ZWO A;  4Z7M A;  1WLR A;  4PNC A;  4HXX A;  4FKC A;  4FUK A;  1YVM A;  4U73 A;  5D6E A;  3IU9 A;  5CIK A;  1WN1 A;  2BHB A;  1YW9 A;  4IKU A;  5FCH A;  2GU4 A;  2GG5 A;  4FLL A;  4FO8 A;  1MAT A;  4IKS A;  4U6E A;  1R5G A;  3MX6 A;  1B6A A;  4RZZ A;  4U69 A;  1XNZ A;  1KQ9 A;  4IU6 A;  4IKT A;  3PKD A;  2GU7 A;  2EVO A;  3Q6D A;  1B59 A;  4U6C A;  4S01 A;  3PKB A;  4U6Z A;  2EA2 A;  2Q95 A;  1JAW A;  1QXY A;  2EA4 A;  1C23 A;  2B3L A;  4PV4 A;  3FM3 A;  1C22 A;  5CDE A;  1CHM A;  5JFR A;  3L7G A;  4MAT A;  2EVC A;  4IF7 A;  2GGB A;  2MAT A;  1XGS A;  1XGO A;  3CB5 A;  2OKN A;  1XGN A;  2V3Y A;  2DFI A;  3MR1 A;  2BWY A;  2V6C A;  2BHA A;  2GGC A;  2Q92 A;  2ZSG A;  3RVA A;  4RZY A;  3IG4 A;  3BIP A;  5CNX A;  4RGZ 1;  3FMR A;  4KM3 A;  2ADU A;  2BHC A;  2B3K A;  2BB7 A;  2GG9 A;  3IU7 A;  2EVM A;  5CLS A;  4U71 A;  1WL6 A;  4JUQ A;  5CE6 A;  3TAV A;  2Q96 A;  2GG0 A;  1M35 A;  1QXW A;  1N51 A;  4FO7 A;  4U1B A;  2NQ6 A;  2BWS A;  1PV9 A;  4ZWP A;  2HOW A;  1R58 A;  4U76 A;  3CB6 A;  4U75 A;  2BWT A;  3BIQ A;  4S2T P;  1C27 A;  5D6F A;  2BHD A;  5FCF A;  2GU5 A;  2G6P A;  3MAT A;  5E5B A;  1R5H A;  2Q93 A;  2GZ5 A;  1BOA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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