3PKDA

M. tuberculosis metap with bengamide analog y10, in mn form
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkdA01
1O0XA 2BH3A 3S6BA 1M35A 2V3XA 2GA2A 2BWWA 4QR8A 1JAWA 1WL9A 2GU4A 1MATA 2BN7A 4S2TP 1WY2A 1C27A 3TB5A 1WN1A 4FO8A 4IDYA 4A6WA 4FLIA 1XGSA 4OOKA 4IKTA 1C23A 1WBQA 1KQ0A 4IPAA 2B3LA 4IU6A 2P99A 4FKCA 3BIPA 3IU7A 2G6PA 4U6WA 4U6EA 2P98A 3IU8A 5CIKA 2BWUA 1C21A 5D6EA 1KQ9A 3FMQA 2GG3A 2BWYA 2Q95A 3CB6A 2NQ6A 4JUQA 2GG8A 2GG2A 5CDLA 3IU9A 4U73A 2GG7A 4KM3A 4RGZ1 4IKSA 1XGOA 4R60A 2OAZA 5JFRA 4U75A 2BWTA 2EVCA 2GG9A 3MR1A 1WLRA 1PV9A 3IG4A 4RZYA 2BWSA 4U6ZA 3RVAA 4Z7MA 5JI6A 4IKUA 1CHMA 1YVMA 1C22A 4FLLA 2NQ7A 2BWVA 5E5BA 2GZ5A 2GGCA 4U76A 2V3YA 2EVMA 2ADUA 2IW2A 5CDEA 3TAVA 3BIQA 1A16A 5CLSA 3PKEA 1YJ3A 1W2MA 2EVOA 2B3HA 3D27A 4RZZA 1BOAA 4IF7A 3L24A 1QXZA 2Q94A 4B28A 4PNCA 3PKAA 3CTZA 5D6FA 2Q8KA 4FLKA 2V6CA 3PKBA 5CDVA 3BITA 1C24A 4U71A 1YW9A 4IECA 4U1BA 5FCFA 4MATA 2HOWA 2Q92A 4S01A 4EGEA 1KP0A 1R5HA 3FM3A 5FCHA 3MATA 4IKRA 2BHDA 1R5GA 1QXYA 2P9AA 5JHUA 2GG0A 4U6JA 2EA4A 1BN5A 2MATA 2V3ZA 4FLJA 1W7VA 1QXWA 2BHBA 2OKNA 4ZNGA 3PKCA 1YW7A 2GU7A 4PV4A 2GGBA 4ZWUA 4S00A 1XGMA 4A6VA 1WL6A 2EA2A 4ZWOA 2Q93A 3Q6DA 2GU5A 2BWXA 4ZWPA 2DFIA 1WKMA 2BHAA 3FMRA 3L7GA 4FUKA 4U6CA 2GG5A 4HXXA 4FO7A 2GU6A 3CB5A 3RORA 1N51A 2BHCA 2BB7A 1XGNA 2GTXA 4U69A 3PKDA 2Q96A 4S2RP 2ZSGA 1XNZA 1Y1NA 1YW8A 4U70A 1B6AA 3MX6A 1B59A 2B3KA 5CNXA 5CE6A 1R58A 1QZYA
chains in the Genus database with same CATH superfamily
1O0XA 2BH3A 3S6BA 1M35A 2V3XA 2GA2A 2BWWA 4QR8A 1JAWA 1WL9A 2GU4A 1MATA 2BN7A 4S2TP 1WY2A 1C27A 3TB5A 1WN1A 4FO8A 4IDYA 4A6WA 4FLIA 1XGSA 4OOKA 4IKTA 1C23A 1WBQA 1KQ0A 4IPAA 2B3LA 4IU6A 2P99A 4FKCA 3BIPA 3IU7A 2G6PA 4U6WA 4U6EA 2P98A 3IU8A 5CIKA 2BWUA 1C21A 5D6EA 1KQ9A 3FMQA 2GG3A 2BWYA 2Q95A 3CB6A 2NQ6A 4JUQA 2GG8A 2GG2A 5CDLA 3IU9A 4U73A 2GG7A 4KM3A 4RGZ1 4IKSA 1XGOA 4R60A 2OAZA 5JFRA 4U75A 2BWTA 2EVCA 2GG9A 3MR1A 1WLRA 1PV9A 3IG4A 4RZYA 2BWSA 4U6ZA 3RVAA 4Z7MA 5JI6A 4IKUA 1CHMA 1YVMA 1C22A 4FLLA 2NQ7A 2BWVA 5E5BA 2GZ5A 2GGCA 4U76A 2V3YA 2EVMA 2ADUA 2IW2A 5CDEA 3TAVA 3BIQA 1A16A 5CLSA 3PKEA 1YJ3A 1W2MA 2EVOA 2B3HA 3D27A 4RZZA 1BOAA 4IF7A 3L24A 1QXZA 2Q94A 4B28A 4PNCA 3PKAA 3CTZA 5D6FA 2Q8KA 4FLKA 2V6CA 3PKBA 5CDVA 3BITA 1C24A 4U71A 1YW9A 4IECA 4U1BA 5FCFA 4MATA 2HOWA 2Q92A 4S01A 4EGEA 1KP0A 1R5HA 3FM3A 5FCHA 3MATA 4IKRA 2BHDA 1R5GA 1QXYA 2P9AA 5JHUA 2GG0A 4U6JA 2EA4A 1BN5A 2MATA 2V3ZA 4FLJA 1W7VA 1QXWA 2BHBA 2OKNA 4ZNGA 3PKCA 1YW7A 2GU7A 4PV4A 2GGBA 4ZWUA 4S00A 1XGMA 4A6VA 1WL6A 2EA2A 4ZWOA 2Q93A 3Q6DA 2GU5A 2BWXA 4ZWPA 2DFIA 1WKMA 2BHAA 3FMRA 3L7GA 4FUKA 4U6CA 2GG5A 4HXXA 4FO7A 2GU6A 3CB5A 3RORA 1N51A 2BHCA 2BB7A 1XGNA 2GTXA 4U69A 3PKDA 2Q96A 4S2RP 2ZSGA 1XNZA 1Y1NA 1YW8A 4U70A 1B6AA 3MX6A 1B59A 2B3KA 5CNXA 5CE6A 1R58A 1QZYA
chains in the Genus database with same CATH topology
1O0XA 2BH3A 3S6BA 1M35A 2V3XA 2GA2A 2BWWA 4QR8A 1JAWA 1WL9A 2GU4A 1MATA 2BN7A 4S2TP 1WY2A 1C27A 3TB5A 1WN1A 4FO8A 4IDYA 4A6WA 4FLIA 1XGSA 4OOKA 4IKTA 1C23A 1WBQA 1KQ0A 4IPAA 2B3LA 4IU6A 2P99A 4FKCA 3BIPA 3IU7A 2G6PA 4U6WA 4U6EA 2P98A 3IU8A 5CIKA 2BWUA 1C21A 5D6EA 1KQ9A 3FMQA 2GG3A 2BWYA 2Q95A 3CB6A 2NQ6A 4JUQA 2GG8A 2GG2A 5CDLA 3IU9A 4U73A 2GG7A 4KM3A 4RGZ1 4IKSA 1XGOA 4R60A 2OAZA 5JFRA 4U75A 2BWTA 2EVCA 2GG9A 3MR1A 1WLRA 1PV9A 3IG4A 4RZYA 2BWSA 4U6ZA 3RVAA 4Z7MA 5JI6A 4IKUA 1CHMA 1YVMA 1C22A 4FLLA 2NQ7A 2BWVA 5E5BA 2GZ5A 2GGCA 4U76A 2V3YA 2EVMA 2ADUA 2IW2A 5CDEA 3TAVA 3BIQA 1A16A 5CLSA 3PKEA 1YJ3A 1W2MA 2EVOA 2B3HA 3D27A 4RZZA 1BOAA 4IF7A 3L24A 1QXZA 2Q94A 4B28A 4PNCA 3PKAA 3CTZA 5D6FA 2Q8KA 4FLKA 2V6CA 3PKBA 5CDVA 3BITA 1C24A 4U71A 1YW9A 4IECA 4U1BA 5FCFA 4MATA 2HOWA 2Q92A 4S01A 4EGEA 1KP0A 1R5HA 3FM3A 5FCHA 3MATA 4IKRA 2BHDA 1R5GA 1QXYA 2P9AA 5JHUA 2GG0A 4U6JA 2EA4A 1BN5A 2MATA 2V3ZA 4FLJA 1W7VA 1QXWA 2BHBA 2OKNA 4ZNGA 3PKCA 1YW7A 2GU7A 4PV4A 2GGBA 4ZWUA 4S00A 1XGMA 4A6VA 1WL6A 2EA2A 4ZWOA 2Q93A 3Q6DA 2GU5A 2BWXA 4ZWPA 2DFIA 1WKMA 2BHAA 3FMRA 3L7GA 4FUKA 4U6CA 2GG5A 4HXXA 4FO7A 2GU6A 3CB5A 3RORA 1N51A 2BHCA 2BB7A 1XGNA 2GTXA 4U69A 3PKDA 2Q96A 4S2RP 2ZSGA 1XNZA 1Y1NA 1YW8A 4U70A 1B6AA 3MX6A 1B59A 2B3KA 5CNXA 5CE6A 1R58A 1QZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O0X A;  2BH3 A;  3S6B A;  1M35 A;  2V3X A;  2GA2 A;  2BWW A;  4QR8 A;  1JAW A;  1WL9 A;  2GU4 A;  1MAT A;  2BN7 A;  4S2T P;  1WY2 A;  1C27 A;  3TB5 A;  1WN1 A;  4FO8 A;  4IDY A;  4A6W A;  4FLI A;  1XGS A;  4OOK A;  4IKT A;  1C23 A;  1WBQ A;  1KQ0 A;  4IPA A;  2B3L A;  4IU6 A;  2P99 A;  4FKC A;  3BIP A;  3IU7 A;  2G6P A;  4U6W A;  4U6E A;  2P98 A;  3IU8 A;  5CIK A;  2BWU A;  1C21 A;  5D6E A;  1KQ9 A;  3FMQ A;  2GG3 A;  2BWY A;  2Q95 A;  3CB6 A;  2NQ6 A;  4JUQ A;  2GG8 A;  2GG2 A;  5CDL A;  3IU9 A;  4U73 A;  2GG7 A;  4KM3 A;  4RGZ 1;  4IKS A;  1XGO A;  4R60 A;  2OAZ A;  5JFR A;  4U75 A;  2BWT A;  2EVC A;  2GG9 A;  3MR1 A;  1WLR A;  1PV9 A;  3IG4 A;  4RZY A;  2BWS A;  4U6Z A;  3RVA A;  4Z7M A;  5JI6 A;  4IKU A;  1CHM A;  1YVM A;  1C22 A;  4FLL A;  2NQ7 A;  2BWV A;  5E5B A;  2GZ5 A;  2GGC A;  4U76 A;  2V3Y A;  2EVM A;  2ADU A;  2IW2 A;  5CDE A;  3TAV A;  3BIQ A;  1A16 A;  5CLS A;  3PKE A;  1YJ3 A;  1W2M A;  2EVO A;  2B3H A;  3D27 A;  4RZZ A;  1BOA A;  4IF7 A;  3L24 A;  1QXZ A;  2Q94 A;  4B28 A;  4PNC A;  3PKA A;  3CTZ A;  5D6F A;  2Q8K A;  4FLK A;  2V6C A;  3PKB A;  5CDV A;  3BIT A;  1C24 A;  4U71 A;  1YW9 A;  4IEC A;  4U1B A;  5FCF A;  4MAT A;  2HOW A;  2Q92 A;  4S01 A;  4EGE A;  1KP0 A;  1R5H A;  3FM3 A;  5FCH A;  3MAT A;  4IKR A;  2BHD A;  1R5G A;  1QXY A;  2P9A A;  5JHU A;  2GG0 A;  4U6J A;  2EA4 A;  1BN5 A;  2MAT A;  2V3Z A;  4FLJ A;  1W7V A;  1QXW A;  2BHB A;  2OKN A;  4ZNG A;  3PKC A;  1YW7 A;  2GU7 A;  4PV4 A;  2GGB A;  4ZWU A;  4S00 A;  1XGM A;  4A6V A;  1WL6 A;  2EA2 A;  4ZWO A;  2Q93 A;  3Q6D A;  2GU5 A;  2BWX A;  4ZWP A;  2DFI A;  1WKM A;  2BHA A;  3FMR A;  3L7G A;  4FUK A;  4U6C A;  2GG5 A;  4HXX A;  4FO7 A;  2GU6 A;  3CB5 A;  3ROR A;  1N51 A;  2BHC A;  2BB7 A;  1XGN A;  2GTX A;  4U69 A;  3PKD A;  2Q96 A;  4S2R P;  2ZSG A;  1XNZ A;  1Y1N A;  1YW8 A;  4U70 A;  1B6A A;  3MX6 A;  1B59 A;  2B3K A;  5CNX A;  5CE6 A;  1R58 A;  1QZY A; 
#chains in the Genus database with same CATH topology
 1O0X A;  2BH3 A;  3S6B A;  1M35 A;  2V3X A;  2GA2 A;  2BWW A;  4QR8 A;  1JAW A;  1WL9 A;  2GU4 A;  1MAT A;  2BN7 A;  4S2T P;  1WY2 A;  1C27 A;  3TB5 A;  1WN1 A;  4FO8 A;  4IDY A;  4A6W A;  4FLI A;  1XGS A;  4OOK A;  4IKT A;  1C23 A;  1WBQ A;  1KQ0 A;  4IPA A;  2B3L A;  4IU6 A;  2P99 A;  4FKC A;  3BIP A;  3IU7 A;  2G6P A;  4U6W A;  4U6E A;  2P98 A;  3IU8 A;  5CIK A;  2BWU A;  1C21 A;  5D6E A;  1KQ9 A;  3FMQ A;  2GG3 A;  2BWY A;  2Q95 A;  3CB6 A;  2NQ6 A;  4JUQ A;  2GG8 A;  2GG2 A;  5CDL A;  3IU9 A;  4U73 A;  2GG7 A;  4KM3 A;  4RGZ 1;  4IKS A;  1XGO A;  4R60 A;  2OAZ A;  5JFR A;  4U75 A;  2BWT A;  2EVC A;  2GG9 A;  3MR1 A;  1WLR A;  1PV9 A;  3IG4 A;  4RZY A;  2BWS A;  4U6Z A;  3RVA A;  4Z7M A;  5JI6 A;  4IKU A;  1CHM A;  1YVM A;  1C22 A;  4FLL A;  2NQ7 A;  2BWV A;  5E5B A;  2GZ5 A;  2GGC A;  4U76 A;  2V3Y A;  2EVM A;  2ADU A;  2IW2 A;  5CDE A;  3TAV A;  3BIQ A;  1A16 A;  5CLS A;  3PKE A;  1YJ3 A;  1W2M A;  2EVO A;  2B3H A;  3D27 A;  4RZZ A;  1BOA A;  4IF7 A;  3L24 A;  1QXZ A;  2Q94 A;  4B28 A;  4PNC A;  3PKA A;  3CTZ A;  5D6F A;  2Q8K A;  4FLK A;  2V6C A;  3PKB A;  5CDV A;  3BIT A;  1C24 A;  4U71 A;  1YW9 A;  4IEC A;  4U1B A;  5FCF A;  4MAT A;  2HOW A;  2Q92 A;  4S01 A;  4EGE A;  1KP0 A;  1R5H A;  3FM3 A;  5FCH A;  3MAT A;  4IKR A;  2BHD A;  1R5G A;  1QXY A;  2P9A A;  5JHU A;  2GG0 A;  4U6J A;  2EA4 A;  1BN5 A;  2MAT A;  2V3Z A;  4FLJ A;  1W7V A;  1QXW A;  2BHB A;  2OKN A;  4ZNG A;  3PKC A;  1YW7 A;  2GU7 A;  4PV4 A;  2GGB A;  4ZWU A;  4S00 A;  1XGM A;  4A6V A;  1WL6 A;  2EA2 A;  4ZWO A;  2Q93 A;  3Q6D A;  2GU5 A;  2BWX A;  4ZWP A;  2DFI A;  1WKM A;  2BHA A;  3FMR A;  3L7G A;  4FUK A;  4U6C A;  2GG5 A;  4HXX A;  4FO7 A;  2GU6 A;  3CB5 A;  3ROR A;  1N51 A;  2BHC A;  2BB7 A;  1XGN A;  2GTX A;  4U69 A;  3PKD A;  2Q96 A;  4S2R P;  2ZSG A;  1XNZ A;  1Y1N A;  1YW8 A;  4U70 A;  1B6A A;  3MX6 A;  1B59 A;  2B3K A;  5CNX A;  5CE6 A;  1R58 A;  1QZY A; 
#chains in the Genus database with same CATH homology
 1O0X A;  2BH3 A;  3S6B A;  1M35 A;  2V3X A;  2GA2 A;  2BWW A;  4QR8 A;  1JAW A;  1WL9 A;  2GU4 A;  1MAT A;  2BN7 A;  4S2T P;  1WY2 A;  1C27 A;  3TB5 A;  1WN1 A;  4FO8 A;  4IDY A;  4A6W A;  4FLI A;  1XGS A;  4OOK A;  4IKT A;  1C23 A;  1WBQ A;  1KQ0 A;  4IPA A;  2B3L A;  4IU6 A;  2P99 A;  4FKC A;  3BIP A;  3IU7 A;  2G6P A;  4U6W A;  4U6E A;  2P98 A;  3IU8 A;  5CIK A;  2BWU A;  1C21 A;  5D6E A;  1KQ9 A;  3FMQ A;  2GG3 A;  2BWY A;  2Q95 A;  3CB6 A;  2NQ6 A;  4JUQ A;  2GG8 A;  2GG2 A;  5CDL A;  3IU9 A;  4U73 A;  2GG7 A;  4KM3 A;  4RGZ 1;  4IKS A;  1XGO A;  4R60 A;  2OAZ A;  5JFR A;  4U75 A;  2BWT A;  2EVC A;  2GG9 A;  3MR1 A;  1WLR A;  1PV9 A;  3IG4 A;  4RZY A;  2BWS A;  4U6Z A;  3RVA A;  4Z7M A;  5JI6 A;  4IKU A;  1CHM A;  1YVM A;  1C22 A;  4FLL A;  2NQ7 A;  2BWV A;  5E5B A;  2GZ5 A;  2GGC A;  4U76 A;  2V3Y A;  2EVM A;  2ADU A;  2IW2 A;  5CDE A;  3TAV A;  3BIQ A;  1A16 A;  5CLS A;  3PKE A;  1YJ3 A;  1W2M A;  2EVO A;  2B3H A;  3D27 A;  4RZZ A;  1BOA A;  4IF7 A;  3L24 A;  1QXZ A;  2Q94 A;  4B28 A;  4PNC A;  3PKA A;  3CTZ A;  5D6F A;  2Q8K A;  4FLK A;  2V6C A;  3PKB A;  5CDV A;  3BIT A;  1C24 A;  4U71 A;  1YW9 A;  4IEC A;  4U1B A;  5FCF A;  4MAT A;  2HOW A;  2Q92 A;  4S01 A;  4EGE A;  1KP0 A;  1R5H A;  3FM3 A;  5FCH A;  3MAT A;  4IKR A;  2BHD A;  1R5G A;  1QXY A;  2P9A A;  5JHU A;  2GG0 A;  4U6J A;  2EA4 A;  1BN5 A;  2MAT A;  2V3Z A;  4FLJ A;  1W7V A;  1QXW A;  2BHB A;  2OKN A;  4ZNG A;  3PKC A;  1YW7 A;  2GU7 A;  4PV4 A;  2GGB A;  4ZWU A;  4S00 A;  1XGM A;  4A6V A;  1WL6 A;  2EA2 A;  4ZWO A;  2Q93 A;  3Q6D A;  2GU5 A;  2BWX A;  4ZWP A;  2DFI A;  1WKM A;  2BHA A;  3FMR A;  3L7G A;  4FUK A;  4U6C A;  2GG5 A;  4HXX A;  4FO7 A;  2GU6 A;  3CB5 A;  3ROR A;  1N51 A;  2BHC A;  2BB7 A;  1XGN A;  2GTX A;  4U69 A;  3PKD A;  2Q96 A;  4S2R P;  2ZSG A;  1XNZ A;  1Y1N A;  1YW8 A;  4U70 A;  1B6A A;  3MX6 A;  1B59 A;  2B3K A;  5CNX A;  5CE6 A;  1R58 A;  1QZY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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