3PKDA

M. tuberculosis metap with bengamide analog y10, in mn form
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
b'RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
molecule tags Hydrolase/hydrolase inhibitor
source organism Mycobacterium tuberculosis
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkdA01
4FUKA 2EVMA 2EVCA 4FLIA 2GG9A 4U71A 2MATA 2EA4A 2GG2A 4KM3A 1R5GA 1XGOA 3FM3A 2Q92A 4ZWPA 4U6CA 2P9AA 5CDEA 2GG3A 2GGBA 4FKCA 1M35A 1JAWA 1XGSA 3RORA 2GG8A 1O0XA 4PNCA 3TB5A 1R58A 4U6ZA 3BIPA 1C27A 3RVAA 1WN1A 2BWVA 4ZWOA 2BWXA 2ZSGA 3PKEA 4U6WA 4B28A 4U76A 1W2MA 2HOWA 2GU5A 2P99A 3CB5A 3L7GA 5CLSA 2B3KA 2EVOA 4MATA 1QXWA 1YW7A 3PKDA 3MR1A 1R5HA 1KP0A 1BN5A 2BN7A 2BWWA 2EA2A 1WY2A 3CB6A 2Q96A 3MX6A 1C23A 1C22A 2BWTA 5D6FA 1B59A 2V3XA 4S00A 2BHCA 3MATA 2NQ7A 3BIQA 5E5BA 4RZYA 1QXYA 2P98A 2V6CA 4EGEA 4U6JA 4IKSA 2V3YA 5FCHA 4IKUA 1KQ9A 2B3LA 2GU4A 4A6WA 2B3HA 1WLRA 5JHUA 1CHMA 2GU6A 1YVMA 2BHAA 1XGMA 2OAZA 2V3ZA 4FO8A 3PKBA 4U1BA 3D27A 4IKTA 2GG7A 1W7VA 1YJ3A 2GG5A 2IW2A 2Q93A 3FMRA 4IECA 4U70A 5D6EA 4IKRA 4HXXA 4FLJA 2BWUA 5CE6A 2NQ6A 1WL9A 1Y1NA 2BHDA 1KQ0A 3Q6DA 3FMQA 4S2TP 3PKAA 4RZZA 3BITA 4U6EA 3IU9A 4IPAA 4FO7A 4U69A 5CNXA 1MATA 1WL6A 2OKNA 3IG4A 4ZNGA 5CIKA 5FCFA 1BOAA 1N51A 1QXZA 4QR8A 2BWSA 2GU7A 4S2RP 4R60A 2BWYA 4RGZ1 2G6PA 4Z7MA 5CDVA 1YW8A 4IF7A 1PV9A 2Q8KA 1C24A 3IU8A 5CDLA 3IU7A 4ZWUA 2GG0A 2BH3A 1B6AA 1QZYA 3CTZA 1XNZA 1WKMA 3L24A 4OOKA 4U73A 2Q94A 3S6BA 2ADUA 4FLKA 2GA2A 4A6VA 1C21A 2BHBA 2GTXA 2BB7A 2Q95A 4FLLA 3TAVA 2GZ5A 1YW9A 1XGNA 2GGCA 5JFRA 5JI6A 1WBQA 2DFIA 4PV4A 4U75A 4IDYA 4JUQA 1A16A 3PKCA 4IU6A 4S01A
chains in the Genus database with same CATH superfamily
4FUKA 2EVMA 2EVCA 4FLIA 2GG9A 4U71A 2MATA 2EA4A 2GG2A 4KM3A 1R5GA 1XGOA 3FM3A 2Q92A 4ZWPA 4U6CA 2P9AA 5CDEA 2GG3A 2GGBA 4FKCA 1M35A 1JAWA 1XGSA 3RORA 2GG8A 1O0XA 4PNCA 3TB5A 1R58A 4U6ZA 3BIPA 1C27A 3RVAA 1WN1A 2BWVA 4ZWOA 2BWXA 2ZSGA 3PKEA 4U6WA 4B28A 4U76A 1W2MA 2HOWA 2GU5A 2P99A 3CB5A 3L7GA 5CLSA 2B3KA 2EVOA 4MATA 1QXWA 1YW7A 3PKDA 3MR1A 1R5HA 1KP0A 1BN5A 2BN7A 2BWWA 2EA2A 1WY2A 3CB6A 2Q96A 3MX6A 1C23A 1C22A 2BWTA 5D6FA 1B59A 2V3XA 4S00A 2BHCA 3MATA 2NQ7A 3BIQA 5E5BA 4RZYA 1QXYA 2P98A 2V6CA 4EGEA 4U6JA 4IKSA 2V3YA 5FCHA 4IKUA 1KQ9A 2B3LA 2GU4A 4A6WA 2B3HA 1WLRA 5JHUA 1CHMA 2GU6A 1YVMA 2BHAA 1XGMA 2OAZA 2V3ZA 4FO8A 3PKBA 4U1BA 3D27A 4IKTA 2GG7A 1W7VA 1YJ3A 2GG5A 2IW2A 2Q93A 3FMRA 4IECA 4U70A 5D6EA 4IKRA 4HXXA 4FLJA 2BWUA 5CE6A 2NQ6A 1WL9A 1Y1NA 2BHDA 1KQ0A 3Q6DA 3FMQA 4S2TP 3PKAA 4RZZA 3BITA 4U6EA 3IU9A 4IPAA 4FO7A 4U69A 5CNXA 1MATA 1WL6A 2OKNA 3IG4A 4ZNGA 5CIKA 5FCFA 1BOAA 1N51A 1QXZA 4QR8A 2BWSA 2GU7A 4S2RP 4R60A 2BWYA 4RGZ1 2G6PA 4Z7MA 5CDVA 1YW8A 4IF7A 1PV9A 2Q8KA 1C24A 3IU8A 5CDLA 3IU7A 4ZWUA 2GG0A 2BH3A 1B6AA 1QZYA 3CTZA 1XNZA 1WKMA 3L24A 4OOKA 4U73A 2Q94A 3S6BA 2ADUA 4FLKA 2GA2A 4A6VA 1C21A 2BHBA 2GTXA 2BB7A 2Q95A 4FLLA 3TAVA 2GZ5A 1YW9A 1XGNA 2GGCA 5JFRA 5JI6A 1WBQA 2DFIA 4PV4A 4U75A 4IDYA 4JUQA 1A16A 3PKCA 4IU6A 4S01A
chains in the Genus database with same CATH topology
4FUKA 2EVMA 2EVCA 4FLIA 2GG9A 4U71A 2MATA 2EA4A 2GG2A 4KM3A 1R5GA 1XGOA 3FM3A 2Q92A 4ZWPA 4U6CA 2P9AA 5CDEA 2GG3A 2GGBA 4FKCA 1M35A 1JAWA 1XGSA 3RORA 2GG8A 1O0XA 4PNCA 3TB5A 1R58A 4U6ZA 3BIPA 1C27A 3RVAA 1WN1A 2BWVA 4ZWOA 2BWXA 2ZSGA 3PKEA 4U6WA 4B28A 4U76A 1W2MA 2HOWA 2GU5A 2P99A 3CB5A 3L7GA 5CLSA 2B3KA 2EVOA 4MATA 1QXWA 1YW7A 3PKDA 3MR1A 1R5HA 1KP0A 1BN5A 2BN7A 2BWWA 2EA2A 1WY2A 3CB6A 2Q96A 3MX6A 1C23A 1C22A 2BWTA 5D6FA 1B59A 2V3XA 4S00A 2BHCA 3MATA 2NQ7A 3BIQA 5E5BA 4RZYA 1QXYA 2P98A 2V6CA 4EGEA 4U6JA 4IKSA 2V3YA 5FCHA 4IKUA 1KQ9A 2B3LA 2GU4A 4A6WA 2B3HA 1WLRA 5JHUA 1CHMA 2GU6A 1YVMA 2BHAA 1XGMA 2OAZA 2V3ZA 4FO8A 3PKBA 4U1BA 3D27A 4IKTA 2GG7A 1W7VA 1YJ3A 2GG5A 2IW2A 2Q93A 3FMRA 4IECA 4U70A 5D6EA 4IKRA 4HXXA 4FLJA 2BWUA 5CE6A 2NQ6A 1WL9A 1Y1NA 2BHDA 1KQ0A 3Q6DA 3FMQA 4S2TP 3PKAA 4RZZA 3BITA 4U6EA 3IU9A 4IPAA 4FO7A 4U69A 5CNXA 1MATA 1WL6A 2OKNA 3IG4A 4ZNGA 5CIKA 5FCFA 1BOAA 1N51A 1QXZA 4QR8A 2BWSA 2GU7A 4S2RP 4R60A 2BWYA 4RGZ1 2G6PA 4Z7MA 5CDVA 1YW8A 4IF7A 1PV9A 2Q8KA 1C24A 3IU8A 5CDLA 3IU7A 4ZWUA 2GG0A 2BH3A 1B6AA 1QZYA 3CTZA 1XNZA 1WKMA 3L24A 4OOKA 4U73A 2Q94A 3S6BA 2ADUA 4FLKA 2GA2A 4A6VA 1C21A 2BHBA 2GTXA 2BB7A 2Q95A 4FLLA 3TAVA 2GZ5A 1YW9A 1XGNA 2GGCA 5JFRA 5JI6A 1WBQA 2DFIA 4PV4A 4U75A 4IDYA 4JUQA 1A16A 3PKCA 4IU6A 4S01A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FUK A;  2EVM A;  2EVC A;  4FLI A;  2GG9 A;  4U71 A;  2MAT A;  2EA4 A;  2GG2 A;  4KM3 A;  1R5G A;  1XGO A;  3FM3 A;  2Q92 A;  4ZWP A;  4U6C A;  2P9A A;  5CDE A;  2GG3 A;  2GGB A;  4FKC A;  1M35 A;  1JAW A;  1XGS A;  3ROR A;  2GG8 A;  1O0X A;  4PNC A;  3TB5 A;  1R58 A;  4U6Z A;  3BIP A;  1C27 A;  3RVA A;  1WN1 A;  2BWV A;  4ZWO A;  2BWX A;  2ZSG A;  3PKE A;  4U6W A;  4B28 A;  4U76 A;  1W2M A;  2HOW A;  2GU5 A;  2P99 A;  3CB5 A;  3L7G A;  5CLS A;  2B3K A;  2EVO A;  4MAT A;  1QXW A;  1YW7 A;  3PKD A;  3MR1 A;  1R5H A;  1KP0 A;  1BN5 A;  2BN7 A;  2BWW A;  2EA2 A;  1WY2 A;  3CB6 A;  2Q96 A;  3MX6 A;  1C23 A;  1C22 A;  2BWT A;  5D6F A;  1B59 A;  2V3X A;  4S00 A;  2BHC A;  3MAT A;  2NQ7 A;  3BIQ A;  5E5B A;  4RZY A;  1QXY A;  2P98 A;  2V6C A;  4EGE A;  4U6J A;  4IKS A;  2V3Y A;  5FCH A;  4IKU A;  1KQ9 A;  2B3L A;  2GU4 A;  4A6W A;  2B3H A;  1WLR A;  5JHU A;  1CHM A;  2GU6 A;  1YVM A;  2BHA A;  1XGM A;  2OAZ A;  2V3Z A;  4FO8 A;  3PKB A;  4U1B A;  3D27 A;  4IKT A;  2GG7 A;  1W7V A;  1YJ3 A;  2GG5 A;  2IW2 A;  2Q93 A;  3FMR A;  4IEC A;  4U70 A;  5D6E A;  4IKR A;  4HXX A;  4FLJ A;  2BWU A;  5CE6 A;  2NQ6 A;  1WL9 A;  1Y1N A;  2BHD A;  1KQ0 A;  3Q6D A;  3FMQ A;  4S2T P;  3PKA A;  4RZZ A;  3BIT A;  4U6E A;  3IU9 A;  4IPA A;  4FO7 A;  4U69 A;  5CNX A;  1MAT A;  1WL6 A;  2OKN A;  3IG4 A;  4ZNG A;  5CIK A;  5FCF A;  1BOA A;  1N51 A;  1QXZ A;  4QR8 A;  2BWS A;  2GU7 A;  4S2R P;  4R60 A;  2BWY A;  4RGZ 1;  2G6P A;  4Z7M A;  5CDV A;  1YW8 A;  4IF7 A;  1PV9 A;  2Q8K A;  1C24 A;  3IU8 A;  5CDL A;  3IU7 A;  4ZWU A;  2GG0 A;  2BH3 A;  1B6A A;  1QZY A;  3CTZ A;  1XNZ A;  1WKM A;  3L24 A;  4OOK A;  4U73 A;  2Q94 A;  3S6B A;  2ADU A;  4FLK A;  2GA2 A;  4A6V A;  1C21 A;  2BHB A;  2GTX A;  2BB7 A;  2Q95 A;  4FLL A;  3TAV A;  2GZ5 A;  1YW9 A;  1XGN A;  2GGC A;  5JFR A;  5JI6 A;  1WBQ A;  2DFI A;  4PV4 A;  4U75 A;  4IDY A;  4JUQ A;  1A16 A;  3PKC A;  4IU6 A;  4S01 A; 
#chains in the Genus database with same CATH topology
 4FUK A;  2EVM A;  2EVC A;  4FLI A;  2GG9 A;  4U71 A;  2MAT A;  2EA4 A;  2GG2 A;  4KM3 A;  1R5G A;  1XGO A;  3FM3 A;  2Q92 A;  4ZWP A;  4U6C A;  2P9A A;  5CDE A;  2GG3 A;  2GGB A;  4FKC A;  1M35 A;  1JAW A;  1XGS A;  3ROR A;  2GG8 A;  1O0X A;  4PNC A;  3TB5 A;  1R58 A;  4U6Z A;  3BIP A;  1C27 A;  3RVA A;  1WN1 A;  2BWV A;  4ZWO A;  2BWX A;  2ZSG A;  3PKE A;  4U6W A;  4B28 A;  4U76 A;  1W2M A;  2HOW A;  2GU5 A;  2P99 A;  3CB5 A;  3L7G A;  5CLS A;  2B3K A;  2EVO A;  4MAT A;  1QXW A;  1YW7 A;  3PKD A;  3MR1 A;  1R5H A;  1KP0 A;  1BN5 A;  2BN7 A;  2BWW A;  2EA2 A;  1WY2 A;  3CB6 A;  2Q96 A;  3MX6 A;  1C23 A;  1C22 A;  2BWT A;  5D6F A;  1B59 A;  2V3X A;  4S00 A;  2BHC A;  3MAT A;  2NQ7 A;  3BIQ A;  5E5B A;  4RZY A;  1QXY A;  2P98 A;  2V6C A;  4EGE A;  4U6J A;  4IKS A;  2V3Y A;  5FCH A;  4IKU A;  1KQ9 A;  2B3L A;  2GU4 A;  4A6W A;  2B3H A;  1WLR A;  5JHU A;  1CHM A;  2GU6 A;  1YVM A;  2BHA A;  1XGM A;  2OAZ A;  2V3Z A;  4FO8 A;  3PKB A;  4U1B A;  3D27 A;  4IKT A;  2GG7 A;  1W7V A;  1YJ3 A;  2GG5 A;  2IW2 A;  2Q93 A;  3FMR A;  4IEC A;  4U70 A;  5D6E A;  4IKR A;  4HXX A;  4FLJ A;  2BWU A;  5CE6 A;  2NQ6 A;  1WL9 A;  1Y1N A;  2BHD A;  1KQ0 A;  3Q6D A;  3FMQ A;  4S2T P;  3PKA A;  4RZZ A;  3BIT A;  4U6E A;  3IU9 A;  4IPA A;  4FO7 A;  4U69 A;  5CNX A;  1MAT A;  1WL6 A;  2OKN A;  3IG4 A;  4ZNG A;  5CIK A;  5FCF A;  1BOA A;  1N51 A;  1QXZ A;  4QR8 A;  2BWS A;  2GU7 A;  4S2R P;  4R60 A;  2BWY A;  4RGZ 1;  2G6P A;  4Z7M A;  5CDV A;  1YW8 A;  4IF7 A;  1PV9 A;  2Q8K A;  1C24 A;  3IU8 A;  5CDL A;  3IU7 A;  4ZWU A;  2GG0 A;  2BH3 A;  1B6A A;  1QZY A;  3CTZ A;  1XNZ A;  1WKM A;  3L24 A;  4OOK A;  4U73 A;  2Q94 A;  3S6B A;  2ADU A;  4FLK A;  2GA2 A;  4A6V A;  1C21 A;  2BHB A;  2GTX A;  2BB7 A;  2Q95 A;  4FLL A;  3TAV A;  2GZ5 A;  1YW9 A;  1XGN A;  2GGC A;  5JFR A;  5JI6 A;  1WBQ A;  2DFI A;  4PV4 A;  4U75 A;  4IDY A;  4JUQ A;  1A16 A;  3PKC A;  4IU6 A;  4S01 A; 
#chains in the Genus database with same CATH homology
 4FUK A;  2EVM A;  2EVC A;  4FLI A;  2GG9 A;  4U71 A;  2MAT A;  2EA4 A;  2GG2 A;  4KM3 A;  1R5G A;  1XGO A;  3FM3 A;  2Q92 A;  4ZWP A;  4U6C A;  2P9A A;  5CDE A;  2GG3 A;  2GGB A;  4FKC A;  1M35 A;  1JAW A;  1XGS A;  3ROR A;  2GG8 A;  1O0X A;  4PNC A;  3TB5 A;  1R58 A;  4U6Z A;  3BIP A;  1C27 A;  3RVA A;  1WN1 A;  2BWV A;  4ZWO A;  2BWX A;  2ZSG A;  3PKE A;  4U6W A;  4B28 A;  4U76 A;  1W2M A;  2HOW A;  2GU5 A;  2P99 A;  3CB5 A;  3L7G A;  5CLS A;  2B3K A;  2EVO A;  4MAT A;  1QXW A;  1YW7 A;  3PKD A;  3MR1 A;  1R5H A;  1KP0 A;  1BN5 A;  2BN7 A;  2BWW A;  2EA2 A;  1WY2 A;  3CB6 A;  2Q96 A;  3MX6 A;  1C23 A;  1C22 A;  2BWT A;  5D6F A;  1B59 A;  2V3X A;  4S00 A;  2BHC A;  3MAT A;  2NQ7 A;  3BIQ A;  5E5B A;  4RZY A;  1QXY A;  2P98 A;  2V6C A;  4EGE A;  4U6J A;  4IKS A;  2V3Y A;  5FCH A;  4IKU A;  1KQ9 A;  2B3L A;  2GU4 A;  4A6W A;  2B3H A;  1WLR A;  5JHU A;  1CHM A;  2GU6 A;  1YVM A;  2BHA A;  1XGM A;  2OAZ A;  2V3Z A;  4FO8 A;  3PKB A;  4U1B A;  3D27 A;  4IKT A;  2GG7 A;  1W7V A;  1YJ3 A;  2GG5 A;  2IW2 A;  2Q93 A;  3FMR A;  4IEC A;  4U70 A;  5D6E A;  4IKR A;  4HXX A;  4FLJ A;  2BWU A;  5CE6 A;  2NQ6 A;  1WL9 A;  1Y1N A;  2BHD A;  1KQ0 A;  3Q6D A;  3FMQ A;  4S2T P;  3PKA A;  4RZZ A;  3BIT A;  4U6E A;  3IU9 A;  4IPA A;  4FO7 A;  4U69 A;  5CNX A;  1MAT A;  1WL6 A;  2OKN A;  3IG4 A;  4ZNG A;  5CIK A;  5FCF A;  1BOA A;  1N51 A;  1QXZ A;  4QR8 A;  2BWS A;  2GU7 A;  4S2R P;  4R60 A;  2BWY A;  4RGZ 1;  2G6P A;  4Z7M A;  5CDV A;  1YW8 A;  4IF7 A;  1PV9 A;  2Q8K A;  1C24 A;  3IU8 A;  5CDL A;  3IU7 A;  4ZWU A;  2GG0 A;  2BH3 A;  1B6A A;  1QZY A;  3CTZ A;  1XNZ A;  1WKM A;  3L24 A;  4OOK A;  4U73 A;  2Q94 A;  3S6B A;  2ADU A;  4FLK A;  2GA2 A;  4A6V A;  1C21 A;  2BHB A;  2GTX A;  2BB7 A;  2Q95 A;  4FLL A;  3TAV A;  2GZ5 A;  1YW9 A;  1XGN A;  2GGC A;  5JFR A;  5JI6 A;  1WBQ A;  2DFI A;  4PV4 A;  4U75 A;  4IDY A;  4JUQ A;  1A16 A;  3PKC A;  4IU6 A;  4S01 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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