3PKDA

M. tuberculosis metap with bengamide analog y10, in mn form
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
b'RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkdA01
2GU5A 3PKBA 4FLKA 4A6VA 5JHUA 1Y1NA 1WN1A 1R5HA 5D6EA 1CHMA 3PKEA 4OOKA 1YW9A 2EVMA 3CTZA 4ZWPA 2MATA 5CDLA 1M35A 2BH3A 2IW2A 1C27A 2DFIA 1XGNA 3BITA 5JI6A 2GG9A 3MR1A 4FO7A 1N51A 1WKMA 1QXWA 1BOAA 3IU7A 4FLIA 4IECA 4ZNGA 1W2MA 1B6AA 1MATA 1YJ3A 2GG8A 1KQ0A 2GZ5A 3CB5A 1PV9A 2EVCA 2Q96A 4U6ZA 4IU6A 3FMQA 3TAVA 4R60A 2BWVA 4U6EA 2V3XA 3L7GA 2BWWA 1W7VA 4PV4A 1XGMA 2V3YA 4S2TP 4IKTA 3RORA 1XGSA 2GU7A 2Q95A 2NQ6A 5CDEA 1QXZA 1YW7A 1O0XA 1B59A 2GA2A 3MX6A 2EVOA 1R5GA 2Q94A 4IKRA 4S00A 2OAZA 2GG5A 1YW8A 2BWSA 3IU9A 2B3LA 3RVAA 4ZWOA 3MATA 4KM3A 1WBQA 2GGBA 2GG2A 3BIQA 4IKSA 1R58A 5CNXA 4RZZA 2BWYA 4U73A 2GG7A 2GU6A 2BHAA 4IF7A 4FLLA 2B3HA 4Z7MA 3S6BA 2GG3A 4FO8A 5FCHA 5D6FA 2GTXA 4MATA 3BIPA 4EGEA 2BHBA 1KP0A 5CE6A 1BN5A 5CLSA 3PKAA 4U69A 2BWXA 1C21A 2P9AA 1KQ9A 1XGOA 2NQ7A 4FUKA 5FCFA 3L24A 3FM3A 2Q93A 4U6WA 2BHCA 1JAWA 2EA2A 2V3ZA 2P99A 4PNCA 4IKUA 5CDVA 2GG0A 4U1BA 3CB6A 4S01A 3FMRA 2OKNA 2EA4A 4S2RP 4U6CA 5JFRA 3PKCA 2GU4A 4U75A 4B28A 4U6JA 5E5BA 2HOWA 1WL6A 4U71A 1C23A 4QR8A 4RGZ1 5CIKA 1QZYA 4IDYA 2Q92A 4FLJA 2BHDA 2GGCA 1C22A 3IG4A 3PKDA 4A6WA 2ADUA 3D27A 2ZSGA 1WL9A 4JUQA 2B3KA 1QXYA 2BB7A 4ZWUA 1WY2A 1WLRA 3IU8A 2Q8KA 3TB5A 4RZYA 1C24A 4U76A 3Q6DA 2BWTA 2G6PA 4FKCA 4U70A 2BN7A 4HXXA 2V6CA 2BWUA 1YVMA 1A16A 2P98A 4IPAA 1XNZA
chains in the Genus database with same CATH superfamily
2GU5A 3PKBA 4FLKA 4A6VA 5JHUA 1Y1NA 1WN1A 1R5HA 5D6EA 1CHMA 3PKEA 4OOKA 1YW9A 2EVMA 3CTZA 4ZWPA 2MATA 5CDLA 1M35A 2BH3A 2IW2A 1C27A 2DFIA 1XGNA 3BITA 5JI6A 2GG9A 3MR1A 4FO7A 1N51A 1WKMA 1QXWA 1BOAA 3IU7A 4FLIA 4IECA 4ZNGA 1W2MA 1B6AA 1MATA 1YJ3A 2GG8A 1KQ0A 2GZ5A 3CB5A 1PV9A 2EVCA 2Q96A 4U6ZA 4IU6A 3FMQA 3TAVA 4R60A 2BWVA 4U6EA 2V3XA 3L7GA 2BWWA 1W7VA 4PV4A 1XGMA 2V3YA 4S2TP 4IKTA 3RORA 1XGSA 2GU7A 2Q95A 2NQ6A 5CDEA 1QXZA 1YW7A 1O0XA 1B59A 2GA2A 3MX6A 2EVOA 1R5GA 2Q94A 4IKRA 4S00A 2OAZA 2GG5A 1YW8A 2BWSA 3IU9A 2B3LA 3RVAA 4ZWOA 3MATA 4KM3A 1WBQA 2GGBA 2GG2A 3BIQA 4IKSA 1R58A 5CNXA 4RZZA 2BWYA 4U73A 2GG7A 2GU6A 2BHAA 4IF7A 4FLLA 2B3HA 4Z7MA 3S6BA 2GG3A 4FO8A 5FCHA 5D6FA 2GTXA 4MATA 3BIPA 4EGEA 2BHBA 1KP0A 5CE6A 1BN5A 5CLSA 3PKAA 4U69A 2BWXA 1C21A 2P9AA 1KQ9A 1XGOA 2NQ7A 4FUKA 5FCFA 3L24A 3FM3A 2Q93A 4U6WA 2BHCA 1JAWA 2EA2A 2V3ZA 2P99A 4PNCA 4IKUA 5CDVA 2GG0A 4U1BA 3CB6A 4S01A 3FMRA 2OKNA 2EA4A 4S2RP 4U6CA 5JFRA 3PKCA 2GU4A 4U75A 4B28A 4U6JA 5E5BA 2HOWA 1WL6A 4U71A 1C23A 4QR8A 4RGZ1 5CIKA 1QZYA 4IDYA 2Q92A 4FLJA 2BHDA 2GGCA 1C22A 3IG4A 3PKDA 4A6WA 2ADUA 3D27A 2ZSGA 1WL9A 4JUQA 2B3KA 1QXYA 2BB7A 4ZWUA 1WY2A 1WLRA 3IU8A 2Q8KA 3TB5A 4RZYA 1C24A 4U76A 3Q6DA 2BWTA 2G6PA 4FKCA 4U70A 2BN7A 4HXXA 2V6CA 2BWUA 1YVMA 1A16A 2P98A 4IPAA 1XNZA
chains in the Genus database with same CATH topology
2GU5A 3PKBA 4FLKA 4A6VA 5JHUA 1Y1NA 1WN1A 1R5HA 5D6EA 1CHMA 3PKEA 4OOKA 1YW9A 2EVMA 3CTZA 4ZWPA 2MATA 5CDLA 1M35A 2BH3A 2IW2A 1C27A 2DFIA 1XGNA 3BITA 5JI6A 2GG9A 3MR1A 4FO7A 1N51A 1WKMA 1QXWA 1BOAA 3IU7A 4FLIA 4IECA 4ZNGA 1W2MA 1B6AA 1MATA 1YJ3A 2GG8A 1KQ0A 2GZ5A 3CB5A 1PV9A 2EVCA 2Q96A 4U6ZA 4IU6A 3FMQA 3TAVA 4R60A 2BWVA 4U6EA 2V3XA 3L7GA 2BWWA 1W7VA 4PV4A 1XGMA 2V3YA 4S2TP 4IKTA 3RORA 1XGSA 2GU7A 2Q95A 2NQ6A 5CDEA 1QXZA 1YW7A 1O0XA 1B59A 2GA2A 3MX6A 2EVOA 1R5GA 2Q94A 4IKRA 4S00A 2OAZA 2GG5A 1YW8A 2BWSA 3IU9A 2B3LA 3RVAA 4ZWOA 3MATA 4KM3A 1WBQA 2GGBA 2GG2A 3BIQA 4IKSA 1R58A 5CNXA 4RZZA 2BWYA 4U73A 2GG7A 2GU6A 2BHAA 4IF7A 4FLLA 2B3HA 4Z7MA 3S6BA 2GG3A 4FO8A 5FCHA 5D6FA 2GTXA 4MATA 3BIPA 4EGEA 2BHBA 1KP0A 5CE6A 1BN5A 5CLSA 3PKAA 4U69A 2BWXA 1C21A 2P9AA 1KQ9A 1XGOA 2NQ7A 4FUKA 5FCFA 3L24A 3FM3A 2Q93A 4U6WA 2BHCA 1JAWA 2EA2A 2V3ZA 2P99A 4PNCA 4IKUA 5CDVA 2GG0A 4U1BA 3CB6A 4S01A 3FMRA 2OKNA 2EA4A 4S2RP 4U6CA 5JFRA 3PKCA 2GU4A 4U75A 4B28A 4U6JA 5E5BA 2HOWA 1WL6A 4U71A 1C23A 4QR8A 4RGZ1 5CIKA 1QZYA 4IDYA 2Q92A 4FLJA 2BHDA 2GGCA 1C22A 3IG4A 3PKDA 4A6WA 2ADUA 3D27A 2ZSGA 1WL9A 4JUQA 2B3KA 1QXYA 2BB7A 4ZWUA 1WY2A 1WLRA 3IU8A 2Q8KA 3TB5A 4RZYA 1C24A 4U76A 3Q6DA 2BWTA 2G6PA 4FKCA 4U70A 2BN7A 4HXXA 2V6CA 2BWUA 1YVMA 1A16A 2P98A 4IPAA 1XNZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GU5 A;  3PKB A;  4FLK A;  4A6V A;  5JHU A;  1Y1N A;  1WN1 A;  1R5H A;  5D6E A;  1CHM A;  3PKE A;  4OOK A;  1YW9 A;  2EVM A;  3CTZ A;  4ZWP A;  2MAT A;  5CDL A;  1M35 A;  2BH3 A;  2IW2 A;  1C27 A;  2DFI A;  1XGN A;  3BIT A;  5JI6 A;  2GG9 A;  3MR1 A;  4FO7 A;  1N51 A;  1WKM A;  1QXW A;  1BOA A;  3IU7 A;  4FLI A;  4IEC A;  4ZNG A;  1W2M A;  1B6A A;  1MAT A;  1YJ3 A;  2GG8 A;  1KQ0 A;  2GZ5 A;  3CB5 A;  1PV9 A;  2EVC A;  2Q96 A;  4U6Z A;  4IU6 A;  3FMQ A;  3TAV A;  4R60 A;  2BWV A;  4U6E A;  2V3X A;  3L7G A;  2BWW A;  1W7V A;  4PV4 A;  1XGM A;  2V3Y A;  4S2T P;  4IKT A;  3ROR A;  1XGS A;  2GU7 A;  2Q95 A;  2NQ6 A;  5CDE A;  1QXZ A;  1YW7 A;  1O0X A;  1B59 A;  2GA2 A;  3MX6 A;  2EVO A;  1R5G A;  2Q94 A;  4IKR A;  4S00 A;  2OAZ A;  2GG5 A;  1YW8 A;  2BWS A;  3IU9 A;  2B3L A;  3RVA A;  4ZWO A;  3MAT A;  4KM3 A;  1WBQ A;  2GGB A;  2GG2 A;  3BIQ A;  4IKS A;  1R58 A;  5CNX A;  4RZZ A;  2BWY A;  4U73 A;  2GG7 A;  2GU6 A;  2BHA A;  4IF7 A;  4FLL A;  2B3H A;  4Z7M A;  3S6B A;  2GG3 A;  4FO8 A;  5FCH A;  5D6F A;  2GTX A;  4MAT A;  3BIP A;  4EGE A;  2BHB A;  1KP0 A;  5CE6 A;  1BN5 A;  5CLS A;  3PKA A;  4U69 A;  2BWX A;  1C21 A;  2P9A A;  1KQ9 A;  1XGO A;  2NQ7 A;  4FUK A;  5FCF A;  3L24 A;  3FM3 A;  2Q93 A;  4U6W A;  2BHC A;  1JAW A;  2EA2 A;  2V3Z A;  2P99 A;  4PNC A;  4IKU A;  5CDV A;  2GG0 A;  4U1B A;  3CB6 A;  4S01 A;  3FMR A;  2OKN A;  2EA4 A;  4S2R P;  4U6C A;  5JFR A;  3PKC A;  2GU4 A;  4U75 A;  4B28 A;  4U6J A;  5E5B A;  2HOW A;  1WL6 A;  4U71 A;  1C23 A;  4QR8 A;  4RGZ 1;  5CIK A;  1QZY A;  4IDY A;  2Q92 A;  4FLJ A;  2BHD A;  2GGC A;  1C22 A;  3IG4 A;  3PKD A;  4A6W A;  2ADU A;  3D27 A;  2ZSG A;  1WL9 A;  4JUQ A;  2B3K A;  1QXY A;  2BB7 A;  4ZWU A;  1WY2 A;  1WLR A;  3IU8 A;  2Q8K A;  3TB5 A;  4RZY A;  1C24 A;  4U76 A;  3Q6D A;  2BWT A;  2G6P A;  4FKC A;  4U70 A;  2BN7 A;  4HXX A;  2V6C A;  2BWU A;  1YVM A;  1A16 A;  2P98 A;  4IPA A;  1XNZ A; 
#chains in the Genus database with same CATH topology
 2GU5 A;  3PKB A;  4FLK A;  4A6V A;  5JHU A;  1Y1N A;  1WN1 A;  1R5H A;  5D6E A;  1CHM A;  3PKE A;  4OOK A;  1YW9 A;  2EVM A;  3CTZ A;  4ZWP A;  2MAT A;  5CDL A;  1M35 A;  2BH3 A;  2IW2 A;  1C27 A;  2DFI A;  1XGN A;  3BIT A;  5JI6 A;  2GG9 A;  3MR1 A;  4FO7 A;  1N51 A;  1WKM A;  1QXW A;  1BOA A;  3IU7 A;  4FLI A;  4IEC A;  4ZNG A;  1W2M A;  1B6A A;  1MAT A;  1YJ3 A;  2GG8 A;  1KQ0 A;  2GZ5 A;  3CB5 A;  1PV9 A;  2EVC A;  2Q96 A;  4U6Z A;  4IU6 A;  3FMQ A;  3TAV A;  4R60 A;  2BWV A;  4U6E A;  2V3X A;  3L7G A;  2BWW A;  1W7V A;  4PV4 A;  1XGM A;  2V3Y A;  4S2T P;  4IKT A;  3ROR A;  1XGS A;  2GU7 A;  2Q95 A;  2NQ6 A;  5CDE A;  1QXZ A;  1YW7 A;  1O0X A;  1B59 A;  2GA2 A;  3MX6 A;  2EVO A;  1R5G A;  2Q94 A;  4IKR A;  4S00 A;  2OAZ A;  2GG5 A;  1YW8 A;  2BWS A;  3IU9 A;  2B3L A;  3RVA A;  4ZWO A;  3MAT A;  4KM3 A;  1WBQ A;  2GGB A;  2GG2 A;  3BIQ A;  4IKS A;  1R58 A;  5CNX A;  4RZZ A;  2BWY A;  4U73 A;  2GG7 A;  2GU6 A;  2BHA A;  4IF7 A;  4FLL A;  2B3H A;  4Z7M A;  3S6B A;  2GG3 A;  4FO8 A;  5FCH A;  5D6F A;  2GTX A;  4MAT A;  3BIP A;  4EGE A;  2BHB A;  1KP0 A;  5CE6 A;  1BN5 A;  5CLS A;  3PKA A;  4U69 A;  2BWX A;  1C21 A;  2P9A A;  1KQ9 A;  1XGO A;  2NQ7 A;  4FUK A;  5FCF A;  3L24 A;  3FM3 A;  2Q93 A;  4U6W A;  2BHC A;  1JAW A;  2EA2 A;  2V3Z A;  2P99 A;  4PNC A;  4IKU A;  5CDV A;  2GG0 A;  4U1B A;  3CB6 A;  4S01 A;  3FMR A;  2OKN A;  2EA4 A;  4S2R P;  4U6C A;  5JFR A;  3PKC A;  2GU4 A;  4U75 A;  4B28 A;  4U6J A;  5E5B A;  2HOW A;  1WL6 A;  4U71 A;  1C23 A;  4QR8 A;  4RGZ 1;  5CIK A;  1QZY A;  4IDY A;  2Q92 A;  4FLJ A;  2BHD A;  2GGC A;  1C22 A;  3IG4 A;  3PKD A;  4A6W A;  2ADU A;  3D27 A;  2ZSG A;  1WL9 A;  4JUQ A;  2B3K A;  1QXY A;  2BB7 A;  4ZWU A;  1WY2 A;  1WLR A;  3IU8 A;  2Q8K A;  3TB5 A;  4RZY A;  1C24 A;  4U76 A;  3Q6D A;  2BWT A;  2G6P A;  4FKC A;  4U70 A;  2BN7 A;  4HXX A;  2V6C A;  2BWU A;  1YVM A;  1A16 A;  2P98 A;  4IPA A;  1XNZ A; 
#chains in the Genus database with same CATH homology
 2GU5 A;  3PKB A;  4FLK A;  4A6V A;  5JHU A;  1Y1N A;  1WN1 A;  1R5H A;  5D6E A;  1CHM A;  3PKE A;  4OOK A;  1YW9 A;  2EVM A;  3CTZ A;  4ZWP A;  2MAT A;  5CDL A;  1M35 A;  2BH3 A;  2IW2 A;  1C27 A;  2DFI A;  1XGN A;  3BIT A;  5JI6 A;  2GG9 A;  3MR1 A;  4FO7 A;  1N51 A;  1WKM A;  1QXW A;  1BOA A;  3IU7 A;  4FLI A;  4IEC A;  4ZNG A;  1W2M A;  1B6A A;  1MAT A;  1YJ3 A;  2GG8 A;  1KQ0 A;  2GZ5 A;  3CB5 A;  1PV9 A;  2EVC A;  2Q96 A;  4U6Z A;  4IU6 A;  3FMQ A;  3TAV A;  4R60 A;  2BWV A;  4U6E A;  2V3X A;  3L7G A;  2BWW A;  1W7V A;  4PV4 A;  1XGM A;  2V3Y A;  4S2T P;  4IKT A;  3ROR A;  1XGS A;  2GU7 A;  2Q95 A;  2NQ6 A;  5CDE A;  1QXZ A;  1YW7 A;  1O0X A;  1B59 A;  2GA2 A;  3MX6 A;  2EVO A;  1R5G A;  2Q94 A;  4IKR A;  4S00 A;  2OAZ A;  2GG5 A;  1YW8 A;  2BWS A;  3IU9 A;  2B3L A;  3RVA A;  4ZWO A;  3MAT A;  4KM3 A;  1WBQ A;  2GGB A;  2GG2 A;  3BIQ A;  4IKS A;  1R58 A;  5CNX A;  4RZZ A;  2BWY A;  4U73 A;  2GG7 A;  2GU6 A;  2BHA A;  4IF7 A;  4FLL A;  2B3H A;  4Z7M A;  3S6B A;  2GG3 A;  4FO8 A;  5FCH A;  5D6F A;  2GTX A;  4MAT A;  3BIP A;  4EGE A;  2BHB A;  1KP0 A;  5CE6 A;  1BN5 A;  5CLS A;  3PKA A;  4U69 A;  2BWX A;  1C21 A;  2P9A A;  1KQ9 A;  1XGO A;  2NQ7 A;  4FUK A;  5FCF A;  3L24 A;  3FM3 A;  2Q93 A;  4U6W A;  2BHC A;  1JAW A;  2EA2 A;  2V3Z A;  2P99 A;  4PNC A;  4IKU A;  5CDV A;  2GG0 A;  4U1B A;  3CB6 A;  4S01 A;  3FMR A;  2OKN A;  2EA4 A;  4S2R P;  4U6C A;  5JFR A;  3PKC A;  2GU4 A;  4U75 A;  4B28 A;  4U6J A;  5E5B A;  2HOW A;  1WL6 A;  4U71 A;  1C23 A;  4QR8 A;  4RGZ 1;  5CIK A;  1QZY A;  4IDY A;  2Q92 A;  4FLJ A;  2BHD A;  2GGC A;  1C22 A;  3IG4 A;  3PKD A;  4A6W A;  2ADU A;  3D27 A;  2ZSG A;  1WL9 A;  4JUQ A;  2B3K A;  1QXY A;  2BB7 A;  4ZWU A;  1WY2 A;  1WLR A;  3IU8 A;  2Q8K A;  3TB5 A;  4RZY A;  1C24 A;  4U76 A;  3Q6D A;  2BWT A;  2G6P A;  4FKC A;  4U70 A;  2BN7 A;  4HXX A;  2V6C A;  2BWU A;  1YVM A;  1A16 A;  2P98 A;  4IPA A;  1XNZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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