3PKDA

M. tuberculosis metap with bengamide analog y10, in mn form
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkdA01
2BWSA 1C24A 2ADUA 3PKEA 2EA2A 3IU8A 4S00A 1B59A 5CIKA 2GG0A 4U70A 4IKSA 4FO8A 4U6CA 3MX6A 1XGOA 3TB5A 2V3ZA 2Q95A 1O0XA 5JFRA 1XGMA 2P99A 4FKCA 4A6VA 1YW7A 2EVMA 2BHAA 2Q92A 4FO7A 4U6WA 2B3KA 3BITA 1R58A 1YW8A 4IKRA 5CE6A 4JUQA 2BB7A 4MATA 4A6WA 3CTZA 4U6ZA 2GA2A 3CB6A 2GG2A 5D6FA 3PKDA 5CDVA 2NQ6A 4FUKA 1PV9A 4U71A 2GU6A 2P9AA 1Y1NA 2OKNA 2GG8A 1C23A 2V3YA 4IU6A 2EVCA 2Q94A 4S01A 5FCHA 1R5HA 3PKAA 4S2RP 2NQ7A 1YJ3A 2G6PA 3TAVA 3FMRA 3MR1A 1WBQA 1WN1A 2EVOA 4PNCA 4EGEA 5CDLA 2B3LA 2GG7A 4PV4A 3IU7A 1WY2A 4ZWOA 5FCFA 2BWVA 2ZSGA 1WLRA 2DFIA 2GGCA 4QR8A 1KQ9A 2GG5A 3IU9A 1MATA 3L24A 5JI6A 4IKTA 2BWTA 4FLJA 1QXZA 3CB5A 4R60A 2GG9A 4U6JA 3BIQA 4U76A 1QZYA 1R5GA 1KQ0A 2Q8KA 1A16A 1N51A 2OAZA 1QXWA 4ZWUA 2BHDA 4IECA 1WKMA 4U73A 2V6CA 1C27A 3MATA 4U1BA 5JHUA 2GU7A 1C22A 3D27A 2GTXA 1BN5A 4FLKA 4RZZA 2BHCA 1CHMA 5CDEA 2GU5A 1JAWA 2BWXA 5D6EA 1BOAA 1QXYA 1YW9A 5CNXA 2GZ5A 2Q93A 3PKBA 1KP0A 2BN7A 4IKUA 1XGNA 2BWYA 4IPAA 1YVMA 5E5BA 5CLSA 4ZWPA 2BHBA 1C21A 2IW2A 4ZNGA 4U6EA 2GG3A 2MATA 2Q96A 4KM3A 2HOWA 4RGZ1 4U69A 1M35A 4U75A 3RORA 2GGBA 1B6AA 4Z7MA 4S2TP 3PKCA 4OOKA 2GU4A 4IF7A 2P98A 3L7GA 3Q6DA 1W2MA 1XGSA 3IG4A 2BH3A 3S6BA 4FLLA 4IDYA 4HXXA 1W7VA 3FMQA 2V3XA 3FM3A 4FLIA 1WL9A 2B3HA 2BWWA 1WL6A 3BIPA 2EA4A 1XNZA 3RVAA 2BWUA 4B28A 4RZYA
chains in the Genus database with same CATH superfamily
2BWSA 1C24A 2ADUA 3PKEA 2EA2A 3IU8A 4S00A 1B59A 5CIKA 2GG0A 4U70A 4IKSA 4FO8A 4U6CA 3MX6A 1XGOA 3TB5A 2V3ZA 2Q95A 1O0XA 5JFRA 1XGMA 2P99A 4FKCA 4A6VA 1YW7A 2EVMA 2BHAA 2Q92A 4FO7A 4U6WA 2B3KA 3BITA 1R58A 1YW8A 4IKRA 5CE6A 4JUQA 2BB7A 4MATA 4A6WA 3CTZA 4U6ZA 2GA2A 3CB6A 2GG2A 5D6FA 3PKDA 5CDVA 2NQ6A 4FUKA 1PV9A 4U71A 2GU6A 2P9AA 1Y1NA 2OKNA 2GG8A 1C23A 2V3YA 4IU6A 2EVCA 2Q94A 4S01A 5FCHA 1R5HA 3PKAA 4S2RP 2NQ7A 1YJ3A 2G6PA 3TAVA 3FMRA 3MR1A 1WBQA 1WN1A 2EVOA 4PNCA 4EGEA 5CDLA 2B3LA 2GG7A 4PV4A 3IU7A 1WY2A 4ZWOA 5FCFA 2BWVA 2ZSGA 1WLRA 2DFIA 2GGCA 4QR8A 1KQ9A 2GG5A 3IU9A 1MATA 3L24A 5JI6A 4IKTA 2BWTA 4FLJA 1QXZA 3CB5A 4R60A 2GG9A 4U6JA 3BIQA 4U76A 1QZYA 1R5GA 1KQ0A 2Q8KA 1A16A 1N51A 2OAZA 1QXWA 4ZWUA 2BHDA 4IECA 1WKMA 4U73A 2V6CA 1C27A 3MATA 4U1BA 5JHUA 2GU7A 1C22A 3D27A 2GTXA 1BN5A 4FLKA 4RZZA 2BHCA 1CHMA 5CDEA 2GU5A 1JAWA 2BWXA 5D6EA 1BOAA 1QXYA 1YW9A 5CNXA 2GZ5A 2Q93A 3PKBA 1KP0A 2BN7A 4IKUA 1XGNA 2BWYA 4IPAA 1YVMA 5E5BA 5CLSA 4ZWPA 2BHBA 1C21A 2IW2A 4ZNGA 4U6EA 2GG3A 2MATA 2Q96A 4KM3A 2HOWA 4RGZ1 4U69A 1M35A 4U75A 3RORA 2GGBA 1B6AA 4Z7MA 4S2TP 3PKCA 4OOKA 2GU4A 4IF7A 2P98A 3L7GA 3Q6DA 1W2MA 1XGSA 3IG4A 2BH3A 3S6BA 4FLLA 4IDYA 4HXXA 1W7VA 3FMQA 2V3XA 3FM3A 4FLIA 1WL9A 2B3HA 2BWWA 1WL6A 3BIPA 2EA4A 1XNZA 3RVAA 2BWUA 4B28A 4RZYA
chains in the Genus database with same CATH topology
2BWSA 1C24A 2ADUA 3PKEA 2EA2A 3IU8A 4S00A 1B59A 5CIKA 2GG0A 4U70A 4IKSA 4FO8A 4U6CA 3MX6A 1XGOA 3TB5A 2V3ZA 2Q95A 1O0XA 5JFRA 1XGMA 2P99A 4FKCA 4A6VA 1YW7A 2EVMA 2BHAA 2Q92A 4FO7A 4U6WA 2B3KA 3BITA 1R58A 1YW8A 4IKRA 5CE6A 4JUQA 2BB7A 4MATA 4A6WA 3CTZA 4U6ZA 2GA2A 3CB6A 2GG2A 5D6FA 3PKDA 5CDVA 2NQ6A 4FUKA 1PV9A 4U71A 2GU6A 2P9AA 1Y1NA 2OKNA 2GG8A 1C23A 2V3YA 4IU6A 2EVCA 2Q94A 4S01A 5FCHA 1R5HA 3PKAA 4S2RP 2NQ7A 1YJ3A 2G6PA 3TAVA 3FMRA 3MR1A 1WBQA 1WN1A 2EVOA 4PNCA 4EGEA 5CDLA 2B3LA 2GG7A 4PV4A 3IU7A 1WY2A 4ZWOA 5FCFA 2BWVA 2ZSGA 1WLRA 2DFIA 2GGCA 4QR8A 1KQ9A 2GG5A 3IU9A 1MATA 3L24A 5JI6A 4IKTA 2BWTA 4FLJA 1QXZA 3CB5A 4R60A 2GG9A 4U6JA 3BIQA 4U76A 1QZYA 1R5GA 1KQ0A 2Q8KA 1A16A 1N51A 2OAZA 1QXWA 4ZWUA 2BHDA 4IECA 1WKMA 4U73A 2V6CA 1C27A 3MATA 4U1BA 5JHUA 2GU7A 1C22A 3D27A 2GTXA 1BN5A 4FLKA 4RZZA 2BHCA 1CHMA 5CDEA 2GU5A 1JAWA 2BWXA 5D6EA 1BOAA 1QXYA 1YW9A 5CNXA 2GZ5A 2Q93A 3PKBA 1KP0A 2BN7A 4IKUA 1XGNA 2BWYA 4IPAA 1YVMA 5E5BA 5CLSA 4ZWPA 2BHBA 1C21A 2IW2A 4ZNGA 4U6EA 2GG3A 2MATA 2Q96A 4KM3A 2HOWA 4RGZ1 4U69A 1M35A 4U75A 3RORA 2GGBA 1B6AA 4Z7MA 4S2TP 3PKCA 4OOKA 2GU4A 4IF7A 2P98A 3L7GA 3Q6DA 1W2MA 1XGSA 3IG4A 2BH3A 3S6BA 4FLLA 4IDYA 4HXXA 1W7VA 3FMQA 2V3XA 3FM3A 4FLIA 1WL9A 2B3HA 2BWWA 1WL6A 3BIPA 2EA4A 1XNZA 3RVAA 2BWUA 4B28A 4RZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BWS A;  1C24 A;  2ADU A;  3PKE A;  2EA2 A;  3IU8 A;  4S00 A;  1B59 A;  5CIK A;  2GG0 A;  4U70 A;  4IKS A;  4FO8 A;  4U6C A;  3MX6 A;  1XGO A;  3TB5 A;  2V3Z A;  2Q95 A;  1O0X A;  5JFR A;  1XGM A;  2P99 A;  4FKC A;  4A6V A;  1YW7 A;  2EVM A;  2BHA A;  2Q92 A;  4FO7 A;  4U6W A;  2B3K A;  3BIT A;  1R58 A;  1YW8 A;  4IKR A;  5CE6 A;  4JUQ A;  2BB7 A;  4MAT A;  4A6W A;  3CTZ A;  4U6Z A;  2GA2 A;  3CB6 A;  2GG2 A;  5D6F A;  3PKD A;  5CDV A;  2NQ6 A;  4FUK A;  1PV9 A;  4U71 A;  2GU6 A;  2P9A A;  1Y1N A;  2OKN A;  2GG8 A;  1C23 A;  2V3Y A;  4IU6 A;  2EVC A;  2Q94 A;  4S01 A;  5FCH A;  1R5H A;  3PKA A;  4S2R P;  2NQ7 A;  1YJ3 A;  2G6P A;  3TAV A;  3FMR A;  3MR1 A;  1WBQ A;  1WN1 A;  2EVO A;  4PNC A;  4EGE A;  5CDL A;  2B3L A;  2GG7 A;  4PV4 A;  3IU7 A;  1WY2 A;  4ZWO A;  5FCF A;  2BWV A;  2ZSG A;  1WLR A;  2DFI A;  2GGC A;  4QR8 A;  1KQ9 A;  2GG5 A;  3IU9 A;  1MAT A;  3L24 A;  5JI6 A;  4IKT A;  2BWT A;  4FLJ A;  1QXZ A;  3CB5 A;  4R60 A;  2GG9 A;  4U6J A;  3BIQ A;  4U76 A;  1QZY A;  1R5G A;  1KQ0 A;  2Q8K A;  1A16 A;  1N51 A;  2OAZ A;  1QXW A;  4ZWU A;  2BHD A;  4IEC A;  1WKM A;  4U73 A;  2V6C A;  1C27 A;  3MAT A;  4U1B A;  5JHU A;  2GU7 A;  1C22 A;  3D27 A;  2GTX A;  1BN5 A;  4FLK A;  4RZZ A;  2BHC A;  1CHM A;  5CDE A;  2GU5 A;  1JAW A;  2BWX A;  5D6E A;  1BOA A;  1QXY A;  1YW9 A;  5CNX A;  2GZ5 A;  2Q93 A;  3PKB A;  1KP0 A;  2BN7 A;  4IKU A;  1XGN A;  2BWY A;  4IPA A;  1YVM A;  5E5B A;  5CLS A;  4ZWP A;  2BHB A;  1C21 A;  2IW2 A;  4ZNG A;  4U6E A;  2GG3 A;  2MAT A;  2Q96 A;  4KM3 A;  2HOW A;  4RGZ 1;  4U69 A;  1M35 A;  4U75 A;  3ROR A;  2GGB A;  1B6A A;  4Z7M A;  4S2T P;  3PKC A;  4OOK A;  2GU4 A;  4IF7 A;  2P98 A;  3L7G A;  3Q6D A;  1W2M A;  1XGS A;  3IG4 A;  2BH3 A;  3S6B A;  4FLL A;  4IDY A;  4HXX A;  1W7V A;  3FMQ A;  2V3X A;  3FM3 A;  4FLI A;  1WL9 A;  2B3H A;  2BWW A;  1WL6 A;  3BIP A;  2EA4 A;  1XNZ A;  3RVA A;  2BWU A;  4B28 A;  4RZY A; 
#chains in the Genus database with same CATH topology
 2BWS A;  1C24 A;  2ADU A;  3PKE A;  2EA2 A;  3IU8 A;  4S00 A;  1B59 A;  5CIK A;  2GG0 A;  4U70 A;  4IKS A;  4FO8 A;  4U6C A;  3MX6 A;  1XGO A;  3TB5 A;  2V3Z A;  2Q95 A;  1O0X A;  5JFR A;  1XGM A;  2P99 A;  4FKC A;  4A6V A;  1YW7 A;  2EVM A;  2BHA A;  2Q92 A;  4FO7 A;  4U6W A;  2B3K A;  3BIT A;  1R58 A;  1YW8 A;  4IKR A;  5CE6 A;  4JUQ A;  2BB7 A;  4MAT A;  4A6W A;  3CTZ A;  4U6Z A;  2GA2 A;  3CB6 A;  2GG2 A;  5D6F A;  3PKD A;  5CDV A;  2NQ6 A;  4FUK A;  1PV9 A;  4U71 A;  2GU6 A;  2P9A A;  1Y1N A;  2OKN A;  2GG8 A;  1C23 A;  2V3Y A;  4IU6 A;  2EVC A;  2Q94 A;  4S01 A;  5FCH A;  1R5H A;  3PKA A;  4S2R P;  2NQ7 A;  1YJ3 A;  2G6P A;  3TAV A;  3FMR A;  3MR1 A;  1WBQ A;  1WN1 A;  2EVO A;  4PNC A;  4EGE A;  5CDL A;  2B3L A;  2GG7 A;  4PV4 A;  3IU7 A;  1WY2 A;  4ZWO A;  5FCF A;  2BWV A;  2ZSG A;  1WLR A;  2DFI A;  2GGC A;  4QR8 A;  1KQ9 A;  2GG5 A;  3IU9 A;  1MAT A;  3L24 A;  5JI6 A;  4IKT A;  2BWT A;  4FLJ A;  1QXZ A;  3CB5 A;  4R60 A;  2GG9 A;  4U6J A;  3BIQ A;  4U76 A;  1QZY A;  1R5G A;  1KQ0 A;  2Q8K A;  1A16 A;  1N51 A;  2OAZ A;  1QXW A;  4ZWU A;  2BHD A;  4IEC A;  1WKM A;  4U73 A;  2V6C A;  1C27 A;  3MAT A;  4U1B A;  5JHU A;  2GU7 A;  1C22 A;  3D27 A;  2GTX A;  1BN5 A;  4FLK A;  4RZZ A;  2BHC A;  1CHM A;  5CDE A;  2GU5 A;  1JAW A;  2BWX A;  5D6E A;  1BOA A;  1QXY A;  1YW9 A;  5CNX A;  2GZ5 A;  2Q93 A;  3PKB A;  1KP0 A;  2BN7 A;  4IKU A;  1XGN A;  2BWY A;  4IPA A;  1YVM A;  5E5B A;  5CLS A;  4ZWP A;  2BHB A;  1C21 A;  2IW2 A;  4ZNG A;  4U6E A;  2GG3 A;  2MAT A;  2Q96 A;  4KM3 A;  2HOW A;  4RGZ 1;  4U69 A;  1M35 A;  4U75 A;  3ROR A;  2GGB A;  1B6A A;  4Z7M A;  4S2T P;  3PKC A;  4OOK A;  2GU4 A;  4IF7 A;  2P98 A;  3L7G A;  3Q6D A;  1W2M A;  1XGS A;  3IG4 A;  2BH3 A;  3S6B A;  4FLL A;  4IDY A;  4HXX A;  1W7V A;  3FMQ A;  2V3X A;  3FM3 A;  4FLI A;  1WL9 A;  2B3H A;  2BWW A;  1WL6 A;  3BIP A;  2EA4 A;  1XNZ A;  3RVA A;  2BWU A;  4B28 A;  4RZY A; 
#chains in the Genus database with same CATH homology
 2BWS A;  1C24 A;  2ADU A;  3PKE A;  2EA2 A;  3IU8 A;  4S00 A;  1B59 A;  5CIK A;  2GG0 A;  4U70 A;  4IKS A;  4FO8 A;  4U6C A;  3MX6 A;  1XGO A;  3TB5 A;  2V3Z A;  2Q95 A;  1O0X A;  5JFR A;  1XGM A;  2P99 A;  4FKC A;  4A6V A;  1YW7 A;  2EVM A;  2BHA A;  2Q92 A;  4FO7 A;  4U6W A;  2B3K A;  3BIT A;  1R58 A;  1YW8 A;  4IKR A;  5CE6 A;  4JUQ A;  2BB7 A;  4MAT A;  4A6W A;  3CTZ A;  4U6Z A;  2GA2 A;  3CB6 A;  2GG2 A;  5D6F A;  3PKD A;  5CDV A;  2NQ6 A;  4FUK A;  1PV9 A;  4U71 A;  2GU6 A;  2P9A A;  1Y1N A;  2OKN A;  2GG8 A;  1C23 A;  2V3Y A;  4IU6 A;  2EVC A;  2Q94 A;  4S01 A;  5FCH A;  1R5H A;  3PKA A;  4S2R P;  2NQ7 A;  1YJ3 A;  2G6P A;  3TAV A;  3FMR A;  3MR1 A;  1WBQ A;  1WN1 A;  2EVO A;  4PNC A;  4EGE A;  5CDL A;  2B3L A;  2GG7 A;  4PV4 A;  3IU7 A;  1WY2 A;  4ZWO A;  5FCF A;  2BWV A;  2ZSG A;  1WLR A;  2DFI A;  2GGC A;  4QR8 A;  1KQ9 A;  2GG5 A;  3IU9 A;  1MAT A;  3L24 A;  5JI6 A;  4IKT A;  2BWT A;  4FLJ A;  1QXZ A;  3CB5 A;  4R60 A;  2GG9 A;  4U6J A;  3BIQ A;  4U76 A;  1QZY A;  1R5G A;  1KQ0 A;  2Q8K A;  1A16 A;  1N51 A;  2OAZ A;  1QXW A;  4ZWU A;  2BHD A;  4IEC A;  1WKM A;  4U73 A;  2V6C A;  1C27 A;  3MAT A;  4U1B A;  5JHU A;  2GU7 A;  1C22 A;  3D27 A;  2GTX A;  1BN5 A;  4FLK A;  4RZZ A;  2BHC A;  1CHM A;  5CDE A;  2GU5 A;  1JAW A;  2BWX A;  5D6E A;  1BOA A;  1QXY A;  1YW9 A;  5CNX A;  2GZ5 A;  2Q93 A;  3PKB A;  1KP0 A;  2BN7 A;  4IKU A;  1XGN A;  2BWY A;  4IPA A;  1YVM A;  5E5B A;  5CLS A;  4ZWP A;  2BHB A;  1C21 A;  2IW2 A;  4ZNG A;  4U6E A;  2GG3 A;  2MAT A;  2Q96 A;  4KM3 A;  2HOW A;  4RGZ 1;  4U69 A;  1M35 A;  4U75 A;  3ROR A;  2GGB A;  1B6A A;  4Z7M A;  4S2T P;  3PKC A;  4OOK A;  2GU4 A;  4IF7 A;  2P98 A;  3L7G A;  3Q6D A;  1W2M A;  1XGS A;  3IG4 A;  2BH3 A;  3S6B A;  4FLL A;  4IDY A;  4HXX A;  1W7V A;  3FMQ A;  2V3X A;  3FM3 A;  4FLI A;  1WL9 A;  2B3H A;  2BWW A;  1WL6 A;  3BIP A;  2EA4 A;  1XNZ A;  3RVA A;  2BWU A;  4B28 A;  4RZY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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