3PKDA

M. tuberculosis metap with bengamide analog y10, in mn form
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkdA01
1XGMA 1YW8A 2GZ5A 5CDVA 2Q8KA 5D6FA 1CHMA 2B3KA 2ZSGA 1C22A 4IKUA 2BWUA 1A16A 5CE6A 2IW2A 1C23A 2BWYA 4FUKA 4A6WA 3Q6DA 3PKEA 1PV9A 2GTXA 4S2TP 4FKCA 4PNCA 4U1BA 2GGBA 1JAWA 4RGZ1 4U76A 4IF7A 4U6CA 2V6CA 4RZYA 2GG7A 3MX6A 4B28A 2GG2A 5E5BA 3MR1A 2BWWA 2ADUA 2GU5A 1WN1A 3L24A 3CTZA 1QXYA 3PKCA 1XGNA 2P99A 2BH3A 4IKRA 2EA4A 3IG4A 4IPAA 2BWXA 2DFIA 2Q93A 2NQ6A 4R60A 5JHUA 2OAZA 2G6PA 1XNZA 4A6VA 2BHDA 2BN7A 3FMRA 2GG5A 4IU6A 3S6BA 1WL6A 4ZWPA 3PKBA 4U6WA 1WL9A 1R58A 2BWSA 5FCHA 2GG9A 3BIQA 1WLRA 2BHCA 2P9AA 4FLIA 2MATA 2V3YA 4U6EA 3PKAA 4FO8A 1KQ0A 1W2MA 1BN5A 3RVAA 4IDYA 4IECA 3L7GA 2GG8A 1QXZA 1R5GA 4MATA 4U6JA 2BB7A 1WKMA 1WY2A 2EVMA 4S2RP 4PV4A 4U69A 4EGEA 2Q96A 1B59A 4IKTA 2EVOA 1XGSA 1O0XA 1C27A 2NQ7A 1YVMA 3FMQA 3IU9A 5JI6A 2GGCA 4HXXA 2EA2A 2GU7A 4S00A 5FCFA 1W7VA 1N51A 4ZNGA 3RORA 5CDEA 1C24A 2Q94A 1M35A 1QXWA 4FLKA 4FO7A 2GU4A 4S01A 3TB5A 2OKNA 2GU6A 3CB5A 5CLSA 5CNXA 3D27A 1BOAA 1C21A 3BIPA 2B3LA 4FLJA 2V3ZA 1XGOA 4IKSA 4JUQA 4ZWUA 2BWTA 2BHBA 1YW7A 2BWVA 2P98A 5CDLA 1MATA 2HOWA 4KM3A 4U71A 2GG0A 4Z7MA 3BITA 1YJ3A 4U6ZA 2V3XA 3PKDA 1Y1NA 3TAVA 4QR8A 2Q95A 5JFRA 1YW9A 4RZZA 4FLLA 2BHAA 2GG3A 3IU8A 4U73A 1WBQA 3IU7A 4OOKA 4U75A 2GA2A 1B6AA 3CB6A 3FM3A 2Q92A 2EVCA 1KQ9A 2B3HA 4U70A 1QZYA 4ZWOA 3MATA 5CIKA 5D6EA 1R5HA 1KP0A
chains in the Genus database with same CATH superfamily
1XGMA 1YW8A 2GZ5A 5CDVA 2Q8KA 5D6FA 1CHMA 2B3KA 2ZSGA 1C22A 4IKUA 2BWUA 1A16A 5CE6A 2IW2A 1C23A 2BWYA 4FUKA 4A6WA 3Q6DA 3PKEA 1PV9A 2GTXA 4S2TP 4FKCA 4PNCA 4U1BA 2GGBA 1JAWA 4RGZ1 4U76A 4IF7A 4U6CA 2V6CA 4RZYA 2GG7A 3MX6A 4B28A 2GG2A 5E5BA 3MR1A 2BWWA 2ADUA 2GU5A 1WN1A 3L24A 3CTZA 1QXYA 3PKCA 1XGNA 2P99A 2BH3A 4IKRA 2EA4A 3IG4A 4IPAA 2BWXA 2DFIA 2Q93A 2NQ6A 4R60A 5JHUA 2OAZA 2G6PA 1XNZA 4A6VA 2BHDA 2BN7A 3FMRA 2GG5A 4IU6A 3S6BA 1WL6A 4ZWPA 3PKBA 4U6WA 1WL9A 1R58A 2BWSA 5FCHA 2GG9A 3BIQA 1WLRA 2BHCA 2P9AA 4FLIA 2MATA 2V3YA 4U6EA 3PKAA 4FO8A 1KQ0A 1W2MA 1BN5A 3RVAA 4IDYA 4IECA 3L7GA 2GG8A 1QXZA 1R5GA 4MATA 4U6JA 2BB7A 1WKMA 1WY2A 2EVMA 4S2RP 4PV4A 4U69A 4EGEA 2Q96A 1B59A 4IKTA 2EVOA 1XGSA 1O0XA 1C27A 2NQ7A 1YVMA 3FMQA 3IU9A 5JI6A 2GGCA 4HXXA 2EA2A 2GU7A 4S00A 5FCFA 1W7VA 1N51A 4ZNGA 3RORA 5CDEA 1C24A 2Q94A 1M35A 1QXWA 4FLKA 4FO7A 2GU4A 4S01A 3TB5A 2OKNA 2GU6A 3CB5A 5CLSA 5CNXA 3D27A 1BOAA 1C21A 3BIPA 2B3LA 4FLJA 2V3ZA 1XGOA 4IKSA 4JUQA 4ZWUA 2BWTA 2BHBA 1YW7A 2BWVA 2P98A 5CDLA 1MATA 2HOWA 4KM3A 4U71A 2GG0A 4Z7MA 3BITA 1YJ3A 4U6ZA 2V3XA 3PKDA 1Y1NA 3TAVA 4QR8A 2Q95A 5JFRA 1YW9A 4RZZA 4FLLA 2BHAA 2GG3A 3IU8A 4U73A 1WBQA 3IU7A 4OOKA 4U75A 2GA2A 1B6AA 3CB6A 3FM3A 2Q92A 2EVCA 1KQ9A 2B3HA 4U70A 1QZYA 4ZWOA 3MATA 5CIKA 5D6EA 1R5HA 1KP0A
chains in the Genus database with same CATH topology
1XGMA 1YW8A 2GZ5A 5CDVA 2Q8KA 5D6FA 1CHMA 2B3KA 2ZSGA 1C22A 4IKUA 2BWUA 1A16A 5CE6A 2IW2A 1C23A 2BWYA 4FUKA 4A6WA 3Q6DA 3PKEA 1PV9A 2GTXA 4S2TP 4FKCA 4PNCA 4U1BA 2GGBA 1JAWA 4RGZ1 4U76A 4IF7A 4U6CA 2V6CA 4RZYA 2GG7A 3MX6A 4B28A 2GG2A 5E5BA 3MR1A 2BWWA 2ADUA 2GU5A 1WN1A 3L24A 3CTZA 1QXYA 3PKCA 1XGNA 2P99A 2BH3A 4IKRA 2EA4A 3IG4A 4IPAA 2BWXA 2DFIA 2Q93A 2NQ6A 4R60A 5JHUA 2OAZA 2G6PA 1XNZA 4A6VA 2BHDA 2BN7A 3FMRA 2GG5A 4IU6A 3S6BA 1WL6A 4ZWPA 3PKBA 4U6WA 1WL9A 1R58A 2BWSA 5FCHA 2GG9A 3BIQA 1WLRA 2BHCA 2P9AA 4FLIA 2MATA 2V3YA 4U6EA 3PKAA 4FO8A 1KQ0A 1W2MA 1BN5A 3RVAA 4IDYA 4IECA 3L7GA 2GG8A 1QXZA 1R5GA 4MATA 4U6JA 2BB7A 1WKMA 1WY2A 2EVMA 4S2RP 4PV4A 4U69A 4EGEA 2Q96A 1B59A 4IKTA 2EVOA 1XGSA 1O0XA 1C27A 2NQ7A 1YVMA 3FMQA 3IU9A 5JI6A 2GGCA 4HXXA 2EA2A 2GU7A 4S00A 5FCFA 1W7VA 1N51A 4ZNGA 3RORA 5CDEA 1C24A 2Q94A 1M35A 1QXWA 4FLKA 4FO7A 2GU4A 4S01A 3TB5A 2OKNA 2GU6A 3CB5A 5CLSA 5CNXA 3D27A 1BOAA 1C21A 3BIPA 2B3LA 4FLJA 2V3ZA 1XGOA 4IKSA 4JUQA 4ZWUA 2BWTA 2BHBA 1YW7A 2BWVA 2P98A 5CDLA 1MATA 2HOWA 4KM3A 4U71A 2GG0A 4Z7MA 3BITA 1YJ3A 4U6ZA 2V3XA 3PKDA 1Y1NA 3TAVA 4QR8A 2Q95A 5JFRA 1YW9A 4RZZA 4FLLA 2BHAA 2GG3A 3IU8A 4U73A 1WBQA 3IU7A 4OOKA 4U75A 2GA2A 1B6AA 3CB6A 3FM3A 2Q92A 2EVCA 1KQ9A 2B3HA 4U70A 1QZYA 4ZWOA 3MATA 5CIKA 5D6EA 1R5HA 1KP0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XGM A;  1YW8 A;  2GZ5 A;  5CDV A;  2Q8K A;  5D6F A;  1CHM A;  2B3K A;  2ZSG A;  1C22 A;  4IKU A;  2BWU A;  1A16 A;  5CE6 A;  2IW2 A;  1C23 A;  2BWY A;  4FUK A;  4A6W A;  3Q6D A;  3PKE A;  1PV9 A;  2GTX A;  4S2T P;  4FKC A;  4PNC A;  4U1B A;  2GGB A;  1JAW A;  4RGZ 1;  4U76 A;  4IF7 A;  4U6C A;  2V6C A;  4RZY A;  2GG7 A;  3MX6 A;  4B28 A;  2GG2 A;  5E5B A;  3MR1 A;  2BWW A;  2ADU A;  2GU5 A;  1WN1 A;  3L24 A;  3CTZ A;  1QXY A;  3PKC A;  1XGN A;  2P99 A;  2BH3 A;  4IKR A;  2EA4 A;  3IG4 A;  4IPA A;  2BWX A;  2DFI A;  2Q93 A;  2NQ6 A;  4R60 A;  5JHU A;  2OAZ A;  2G6P A;  1XNZ A;  4A6V A;  2BHD A;  2BN7 A;  3FMR A;  2GG5 A;  4IU6 A;  3S6B A;  1WL6 A;  4ZWP A;  3PKB A;  4U6W A;  1WL9 A;  1R58 A;  2BWS A;  5FCH A;  2GG9 A;  3BIQ A;  1WLR A;  2BHC A;  2P9A A;  4FLI A;  2MAT A;  2V3Y A;  4U6E A;  3PKA A;  4FO8 A;  1KQ0 A;  1W2M A;  1BN5 A;  3RVA A;  4IDY A;  4IEC A;  3L7G A;  2GG8 A;  1QXZ A;  1R5G A;  4MAT A;  4U6J A;  2BB7 A;  1WKM A;  1WY2 A;  2EVM A;  4S2R P;  4PV4 A;  4U69 A;  4EGE A;  2Q96 A;  1B59 A;  4IKT A;  2EVO A;  1XGS A;  1O0X A;  1C27 A;  2NQ7 A;  1YVM A;  3FMQ A;  3IU9 A;  5JI6 A;  2GGC A;  4HXX A;  2EA2 A;  2GU7 A;  4S00 A;  5FCF A;  1W7V A;  1N51 A;  4ZNG A;  3ROR A;  5CDE A;  1C24 A;  2Q94 A;  1M35 A;  1QXW A;  4FLK A;  4FO7 A;  2GU4 A;  4S01 A;  3TB5 A;  2OKN A;  2GU6 A;  3CB5 A;  5CLS A;  5CNX A;  3D27 A;  1BOA A;  1C21 A;  3BIP A;  2B3L A;  4FLJ A;  2V3Z A;  1XGO A;  4IKS A;  4JUQ A;  4ZWU A;  2BWT A;  2BHB A;  1YW7 A;  2BWV A;  2P98 A;  5CDL A;  1MAT A;  2HOW A;  4KM3 A;  4U71 A;  2GG0 A;  4Z7M A;  3BIT A;  1YJ3 A;  4U6Z A;  2V3X A;  3PKD A;  1Y1N A;  3TAV A;  4QR8 A;  2Q95 A;  5JFR A;  1YW9 A;  4RZZ A;  4FLL A;  2BHA A;  2GG3 A;  3IU8 A;  4U73 A;  1WBQ A;  3IU7 A;  4OOK A;  4U75 A;  2GA2 A;  1B6A A;  3CB6 A;  3FM3 A;  2Q92 A;  2EVC A;  1KQ9 A;  2B3H A;  4U70 A;  1QZY A;  4ZWO A;  3MAT A;  5CIK A;  5D6E A;  1R5H A;  1KP0 A; 
#chains in the Genus database with same CATH topology
 1XGM A;  1YW8 A;  2GZ5 A;  5CDV A;  2Q8K A;  5D6F A;  1CHM A;  2B3K A;  2ZSG A;  1C22 A;  4IKU A;  2BWU A;  1A16 A;  5CE6 A;  2IW2 A;  1C23 A;  2BWY A;  4FUK A;  4A6W A;  3Q6D A;  3PKE A;  1PV9 A;  2GTX A;  4S2T P;  4FKC A;  4PNC A;  4U1B A;  2GGB A;  1JAW A;  4RGZ 1;  4U76 A;  4IF7 A;  4U6C A;  2V6C A;  4RZY A;  2GG7 A;  3MX6 A;  4B28 A;  2GG2 A;  5E5B A;  3MR1 A;  2BWW A;  2ADU A;  2GU5 A;  1WN1 A;  3L24 A;  3CTZ A;  1QXY A;  3PKC A;  1XGN A;  2P99 A;  2BH3 A;  4IKR A;  2EA4 A;  3IG4 A;  4IPA A;  2BWX A;  2DFI A;  2Q93 A;  2NQ6 A;  4R60 A;  5JHU A;  2OAZ A;  2G6P A;  1XNZ A;  4A6V A;  2BHD A;  2BN7 A;  3FMR A;  2GG5 A;  4IU6 A;  3S6B A;  1WL6 A;  4ZWP A;  3PKB A;  4U6W A;  1WL9 A;  1R58 A;  2BWS A;  5FCH A;  2GG9 A;  3BIQ A;  1WLR A;  2BHC A;  2P9A A;  4FLI A;  2MAT A;  2V3Y A;  4U6E A;  3PKA A;  4FO8 A;  1KQ0 A;  1W2M A;  1BN5 A;  3RVA A;  4IDY A;  4IEC A;  3L7G A;  2GG8 A;  1QXZ A;  1R5G A;  4MAT A;  4U6J A;  2BB7 A;  1WKM A;  1WY2 A;  2EVM A;  4S2R P;  4PV4 A;  4U69 A;  4EGE A;  2Q96 A;  1B59 A;  4IKT A;  2EVO A;  1XGS A;  1O0X A;  1C27 A;  2NQ7 A;  1YVM A;  3FMQ A;  3IU9 A;  5JI6 A;  2GGC A;  4HXX A;  2EA2 A;  2GU7 A;  4S00 A;  5FCF A;  1W7V A;  1N51 A;  4ZNG A;  3ROR A;  5CDE A;  1C24 A;  2Q94 A;  1M35 A;  1QXW A;  4FLK A;  4FO7 A;  2GU4 A;  4S01 A;  3TB5 A;  2OKN A;  2GU6 A;  3CB5 A;  5CLS A;  5CNX A;  3D27 A;  1BOA A;  1C21 A;  3BIP A;  2B3L A;  4FLJ A;  2V3Z A;  1XGO A;  4IKS A;  4JUQ A;  4ZWU A;  2BWT A;  2BHB A;  1YW7 A;  2BWV A;  2P98 A;  5CDL A;  1MAT A;  2HOW A;  4KM3 A;  4U71 A;  2GG0 A;  4Z7M A;  3BIT A;  1YJ3 A;  4U6Z A;  2V3X A;  3PKD A;  1Y1N A;  3TAV A;  4QR8 A;  2Q95 A;  5JFR A;  1YW9 A;  4RZZ A;  4FLL A;  2BHA A;  2GG3 A;  3IU8 A;  4U73 A;  1WBQ A;  3IU7 A;  4OOK A;  4U75 A;  2GA2 A;  1B6A A;  3CB6 A;  3FM3 A;  2Q92 A;  2EVC A;  1KQ9 A;  2B3H A;  4U70 A;  1QZY A;  4ZWO A;  3MAT A;  5CIK A;  5D6E A;  1R5H A;  1KP0 A; 
#chains in the Genus database with same CATH homology
 1XGM A;  1YW8 A;  2GZ5 A;  5CDV A;  2Q8K A;  5D6F A;  1CHM A;  2B3K A;  2ZSG A;  1C22 A;  4IKU A;  2BWU A;  1A16 A;  5CE6 A;  2IW2 A;  1C23 A;  2BWY A;  4FUK A;  4A6W A;  3Q6D A;  3PKE A;  1PV9 A;  2GTX A;  4S2T P;  4FKC A;  4PNC A;  4U1B A;  2GGB A;  1JAW A;  4RGZ 1;  4U76 A;  4IF7 A;  4U6C A;  2V6C A;  4RZY A;  2GG7 A;  3MX6 A;  4B28 A;  2GG2 A;  5E5B A;  3MR1 A;  2BWW A;  2ADU A;  2GU5 A;  1WN1 A;  3L24 A;  3CTZ A;  1QXY A;  3PKC A;  1XGN A;  2P99 A;  2BH3 A;  4IKR A;  2EA4 A;  3IG4 A;  4IPA A;  2BWX A;  2DFI A;  2Q93 A;  2NQ6 A;  4R60 A;  5JHU A;  2OAZ A;  2G6P A;  1XNZ A;  4A6V A;  2BHD A;  2BN7 A;  3FMR A;  2GG5 A;  4IU6 A;  3S6B A;  1WL6 A;  4ZWP A;  3PKB A;  4U6W A;  1WL9 A;  1R58 A;  2BWS A;  5FCH A;  2GG9 A;  3BIQ A;  1WLR A;  2BHC A;  2P9A A;  4FLI A;  2MAT A;  2V3Y A;  4U6E A;  3PKA A;  4FO8 A;  1KQ0 A;  1W2M A;  1BN5 A;  3RVA A;  4IDY A;  4IEC A;  3L7G A;  2GG8 A;  1QXZ A;  1R5G A;  4MAT A;  4U6J A;  2BB7 A;  1WKM A;  1WY2 A;  2EVM A;  4S2R P;  4PV4 A;  4U69 A;  4EGE A;  2Q96 A;  1B59 A;  4IKT A;  2EVO A;  1XGS A;  1O0X A;  1C27 A;  2NQ7 A;  1YVM A;  3FMQ A;  3IU9 A;  5JI6 A;  2GGC A;  4HXX A;  2EA2 A;  2GU7 A;  4S00 A;  5FCF A;  1W7V A;  1N51 A;  4ZNG A;  3ROR A;  5CDE A;  1C24 A;  2Q94 A;  1M35 A;  1QXW A;  4FLK A;  4FO7 A;  2GU4 A;  4S01 A;  3TB5 A;  2OKN A;  2GU6 A;  3CB5 A;  5CLS A;  5CNX A;  3D27 A;  1BOA A;  1C21 A;  3BIP A;  2B3L A;  4FLJ A;  2V3Z A;  1XGO A;  4IKS A;  4JUQ A;  4ZWU A;  2BWT A;  2BHB A;  1YW7 A;  2BWV A;  2P98 A;  5CDL A;  1MAT A;  2HOW A;  4KM3 A;  4U71 A;  2GG0 A;  4Z7M A;  3BIT A;  1YJ3 A;  4U6Z A;  2V3X A;  3PKD A;  1Y1N A;  3TAV A;  4QR8 A;  2Q95 A;  5JFR A;  1YW9 A;  4RZZ A;  4FLL A;  2BHA A;  2GG3 A;  3IU8 A;  4U73 A;  1WBQ A;  3IU7 A;  4OOK A;  4U75 A;  2GA2 A;  1B6A A;  3CB6 A;  3FM3 A;  2Q92 A;  2EVC A;  1KQ9 A;  2B3H A;  4U70 A;  1QZY A;  4ZWO A;  3MAT A;  5CIK A;  5D6E A;  1R5H A;  1KP0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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