3PQBA

The crystal structure of pregilvocarcin in complex with gilr, an oxidoreductase that catalyzes the terminal step of gilvocarcin biosynthesis
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
492
structure length
492
Chain Sequence
b'PFTVGREDPRYIELSHSDNHRFVVEPEEFFLPATPDDVVASLQKAVTEGRGVACRSGGHCGQDFVGTPRRDLVLDLHNLHAIGPAADGAGVRVGSGATVDQVQKALFRRWNAALPLGACSAVGMGGLVAGGGYGPLSRQLGLVVDHLHAVEVAVVDESRTVRLVTARADDTGDLGELFWAHTGGGGGNFGVVTAYEFRSPEHLATEPVGLPRAAGRLHVQKVVFPWAMIDETSFVTVMRRFFEWHERHSEPGSPESSLFATFFVNHVSSGVLQLMVQQDADVDPEGEILARFVASLTEGTGVVGIPRGGVMSWLTGTRYMSQADCGDVMGARSASKSAYHRAAPTDEQLSVLHRHLHADHPGQASYVMFNSYGGEINRRGPSDAAVPQRDSVVKSSWFSAWQDAELDELHLGWLRGLYEEFFAGTGGVPVTGGRTDGCYINYPDADLLDPARNRSGEPWHHLYYKDNYARLRSAKRAWDPLNTFHHSMSIGL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Putative oxidoreductase
publication title The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis.
pubmed doi rcsb
source organism Streptomyces griseoflavus
molecule tags Oxidoreductase
total genus 165
structure length 492
sequence length 492
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.465.40 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3pqbA01
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3pqbA02
5AWVA 2Y3RA 5I1VA 4PVHA 3POPA 2UUUA 3HSUA 2BVGA 3GSYA 1ZR6A 5L6GA 3TSHA 3RJ8A 3VTEA 2UUVA 3FW8A 5D79A 3FW7A 4PZFA 3W8ZA 2Y3SA 2BVHA 3W8WA 3RJAA 5K8EA 2Y08A 4PVKA 4PVEA 4UD8A 4EC3A 3FW9A 3W8XA 2AXRA 4PWBA 4PWCA 2IPIA 3PQBA 2BVFA 3TSJA 5L6FA 4DNSA 3D2DA 3FWAA 4XLOA 2WDWA 2Y4GA 5I1WA 4PVJA 3D2JA 3D2HA
chains in the Genus database with same CATH superfamily
5AWVA 1MBTA 2Y3RA 2OAIA 3C0PA 3I99A 3POPA 1E8HA 1ZXIC 2GQTA 1DIIA 1MBBA 2UUUA 1QLTA 3RJ8A 5L6GA 1E0YA 1WYGA 2VFUA 3FW8A 2PLIA 3FW7A 1W1SA 2Y3SA 1N63C 1V97A 2QKNA 2Y08A 5K8EA 4ZOHB 1WVFA 2EXRA 2P4PA 2YVSA 3ETRB 5AE2A 1E8FA 3S1DA 1AHUA 1W1LA 4O95A 4BC7A 4DNSA 3FWAA 2E3TA 2WDWA 4PVJA 3AM9A 1DIQA 2PLSA 3TX1A 5I1VA 3DEDA 3DQ0A 3HSUA 5AE1A 3TSHA 3BW7A 2NQWA 2UUVA 3D2HA 3NVVB 5D79A 3NVYB 1FIQB 1SB3B 5FXFA 3W8ZA 1W1RA 1N5WC 3S1CA 2P13A 3W8WA 2RK5A 1FFVC 3JS8A 3B9JB 4UD8A 3W8XA 1WVEA 1N62C 2IPIA 1AHVA 3NRZB 5FXDA 5L6FA 4XLOA 5HHZA 1QLUA 1N5XA 3NVZB 4PVHA 1HSKA 1T3QC 3S1FA 2VFSA 3VTEA 1VDVA 4PYTA 1ZR6A 2VFTA 2VFVA 1UXYA 4BCAA 5AE3A 1DZNA 3SR6B 4PZFA 5HMRA 2MBRA 4BBYA 2BVHA 2P3HA 5FXEA 5HQXA 2VFRA 5FXPA 1W1MA 2W3SA 3FW9A 1F0XA 1N60C 1W1QA 4JAYA 4PWCA 4ML8A 2GQUA 2R8DA 3EUB3 4JB1A 1AHZA 1W1OA 2W3RA 3AMZA 5ADZA 2VAOA 3TSJA 2QPMA 1I19A 1FFUC 3KJMA 2Q4WA 2BVGA 3GSYA 2W54A 1RM6B 2O3GA 3LAEA 3NVWB 1E8GA 1W1KA 3AN1A 4OALA 5G5GB 4MLAA 2Q85A 4BC9A 3RJAA 4PVKA 4PVEA 3LLBA 4HG0A 3HRDC 4EC3A 2W55A 1JROA 2AXRA 4PWBA 1VAOA 1N61C 2R2ZA 1JRPA 3PQBA 2BVFA 1FO4A 3D2DA 3S1EA 3PM9A 1W1JA 2Y4GA 5I1WA 5G5HB 3D2JA 3NS1B 2I0KA
chains in the Genus database with same CATH topology
5AWVA 1MBTA 2Y3RA 2OAIA 3C0PA 3I99A 3POPA 1E8HA 1ZXIC 2GQTA 1DIIA 1MBBA 2UUUA 1QLTA 3RJ8A 5L6GA 1E0YA 1WYGA 2VFUA 3FW8A 2PLIA 3FW7A 1W1SA 2Y3SA 1N63C 1V97A 2QKNA 2Y08A 5K8EA 4ZOHB 1WVFA 2EXRA 2P4PA 2YVSA 3ETRB 5AE2A 1E8FA 3S1DA 1AHUA 1W1LA 4O95A 4BC7A 4DNSA 3FWAA 2E3TA 2WDWA 4PVJA 3AM9A 1DIQA 2PLSA 3TX1A 5I1VA 3DEDA 3DQ0A 3HSUA 5AE1A 3TSHA 3BW7A 2NQWA 2UUVA 3D2HA 3NVVB 5D79A 3NVYB 1FIQB 1SB3B 5FXFA 3W8ZA 1W1RA 1N5WC 3S1CA 2P13A 3W8WA 2RK5A 1FFVC 3JS8A 3B9JB 4UD8A 3W8XA 1WVEA 1N62C 2IPIA 1AHVA 3NRZB 5FXDA 5L6FA 4XLOA 5HHZA 1QLUA 1N5XA 3NVZB 4PVHA 1HSKA 1T3QC 3S1FA 2VFSA 3VTEA 1VDVA 4PYTA 1ZR6A 2VFTA 2VFVA 1UXYA 4BCAA 5AE3A 1DZNA 3SR6B 4PZFA 5HMRA 2MBRA 4BBYA 2BVHA 2P3HA 5FXEA 5HQXA 2VFRA 5FXPA 1W1MA 2W3SA 3FW9A 1F0XA 1N60C 1W1QA 4JAYA 4PWCA 4ML8A 2GQUA 2R8DA 3EUB3 4JB1A 1AHZA 1W1OA 2W3RA 3AMZA 5ADZA 2VAOA 3TSJA 2QPMA 1I19A 1FFUC 3KJMA 2Q4WA 2BVGA 3GSYA 2W54A 1RM6B 2O3GA 3LAEA 3NVWB 1E8GA 1W1KA 3AN1A 4OALA 5G5GB 4MLAA 2Q85A 4BC9A 3RJAA 4PVKA 4PVEA 3LLBA 4HG0A 3HRDC 4EC3A 2W55A 1JROA 2AXRA 4PWBA 1VAOA 1N61C 2R2ZA 1JRPA 3PQBA 2BVFA 1FO4A 3D2DA 3S1EA 3PM9A 1W1JA 2Y4GA 5I1WA 5G5HB 3D2JA 3NS1B 2I0KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AWV A;  2Y3R A;  5I1V A;  4PVH A;  3POP A;  2UUU A;  3HSU A;  2BVG A;  3GSY A;  1ZR6 A;  5L6G A;  3TSH A;  3RJ8 A;  3VTE A;  2UUV A;  3FW8 A;  5D79 A;  3FW7 A;  4PZF A;  3W8Z A;  2Y3S A;  2BVH A;  3W8W A;  3RJA A;  5K8E A;  2Y08 A;  4PVK A;  4PVE A;  4UD8 A;  4EC3 A;  3FW9 A;  3W8X A;  2AXR A;  4PWB A;  4PWC A;  2IPI A;  3PQB A;  2BVF A;  3TSJ A;  5L6F A;  4DNS A;  3D2D A;  3FWA A;  4XLO A;  2WDW A;  2Y4G A;  5I1W A;  4PVJ A;  3D2J A;  3D2H A; 
#chains in the Genus database with same CATH topology
 5AWV A;  1MBT A;  2Y3R A;  2OAI A;  3C0P A;  3I99 A;  3POP A;  1E8H A;  1ZXI C;  2GQT A;  1DII A;  1MBB A;  2UUU A;  1QLT A;  3RJ8 A;  5L6G A;  1E0Y A;  1WYG A;  2VFU A;  3FW8 A;  2PLI A;  3FW7 A;  1W1S A;  2Y3S A;  1N63 C;  1V97 A;  2QKN A;  2Y08 A;  5K8E A;  4ZOH B;  1WVF A;  2EXR A;  2P4P A;  2YVS A;  3ETR B;  5AE2 A;  1E8F A;  3S1D A;  1AHU A;  1W1L A;  4O95 A;  4BC7 A;  4DNS A;  3FWA A;  2E3T A;  2WDW A;  4PVJ A;  3AM9 A;  1DIQ A;  2PLS A;  3TX1 A;  5I1V A;  3DED A;  3DQ0 A;  3HSU A;  5AE1 A;  3TSH A;  3BW7 A;  2NQW A;  2UUV A;  3D2H A;  3NVV B;  5D79 A;  3NVY B;  1FIQ B;  1SB3 B;  5FXF A;  3W8Z A;  1W1R A;  1N5W C;  3S1C A;  2P13 A;  3W8W A;  2RK5 A;  1FFV C;  3JS8 A;  3B9J B;  4UD8 A;  3W8X A;  1WVE A;  1N62 C;  2IPI A;  1AHV A;  3NRZ B;  5FXD A;  5L6F A;  4XLO A;  5HHZ A;  1QLU A;  1N5X A;  3NVZ B;  4PVH A;  1HSK A;  1T3Q C;  3S1F A;  2VFS A;  3VTE A;  1VDV A;  4PYT A;  1ZR6 A;  2VFT A;  2VFV A;  1UXY A;  4BCA A;  5AE3 A;  1DZN A;  3SR6 B;  4PZF A;  5HMR A;  2MBR A;  4BBY A;  2BVH A;  2P3H A;  5FXE A;  5HQX A;  2VFR A;  5FXP A;  1W1M A;  2W3S A;  3FW9 A;  1F0X A;  1N60 C;  1W1Q A;  4JAY A;  4PWC A;  4ML8 A;  2GQU A;  2R8D A;  3EUB 3;  4JB1 A;  1AHZ A;  1W1O A;  2W3R A;  3AMZ A;  5ADZ A;  2VAO A;  3TSJ A;  2QPM A;  1I19 A;  1FFU C;  3KJM A;  2Q4W A;  2BVG A;  3GSY A;  2W54 A;  1RM6 B;  2O3G A;  3LAE A;  3NVW B;  1E8G A;  1W1K A;  3AN1 A;  4OAL A;  5G5G B;  4MLA A;  2Q85 A;  4BC9 A;  3RJA A;  4PVK A;  4PVE A;  3LLB A;  4HG0 A;  3HRD C;  4EC3 A;  2W55 A;  1JRO A;  2AXR A;  4PWB A;  1VAO A;  1N61 C;  2R2Z A;  1JRP A;  3PQB A;  2BVF A;  1FO4 A;  3D2D A;  3S1E A;  3PM9 A;  1W1J A;  2Y4G A;  5I1W A;  5G5H B;  3D2J A;  3NS1 B;  2I0K A; 
#chains in the Genus database with same CATH homology
 5AWV A;  1MBT A;  2Y3R A;  2OAI A;  3C0P A;  3I99 A;  3POP A;  1E8H A;  1ZXI C;  2GQT A;  1DII A;  1MBB A;  2UUU A;  1QLT A;  3RJ8 A;  5L6G A;  1E0Y A;  1WYG A;  2VFU A;  3FW8 A;  2PLI A;  3FW7 A;  1W1S A;  2Y3S A;  1N63 C;  1V97 A;  2QKN A;  2Y08 A;  5K8E A;  4ZOH B;  1WVF A;  2EXR A;  2P4P A;  2YVS A;  3ETR B;  5AE2 A;  1E8F A;  3S1D A;  1AHU A;  1W1L A;  4O95 A;  4BC7 A;  4DNS A;  3FWA A;  2E3T A;  2WDW A;  4PVJ A;  3AM9 A;  1DIQ A;  2PLS A;  3TX1 A;  5I1V A;  3DED A;  3DQ0 A;  3HSU A;  5AE1 A;  3TSH A;  3BW7 A;  2NQW A;  2UUV A;  3D2H A;  3NVV B;  5D79 A;  3NVY B;  1FIQ B;  1SB3 B;  5FXF A;  3W8Z A;  1W1R A;  1N5W C;  3S1C A;  2P13 A;  3W8W A;  2RK5 A;  1FFV C;  3JS8 A;  3B9J B;  4UD8 A;  3W8X A;  1WVE A;  1N62 C;  2IPI A;  1AHV A;  3NRZ B;  5FXD A;  5L6F A;  4XLO A;  5HHZ A;  1QLU A;  1N5X A;  3NVZ B;  4PVH A;  1HSK A;  1T3Q C;  3S1F A;  2VFS A;  3VTE A;  1VDV A;  4PYT A;  1ZR6 A;  2VFT A;  2VFV A;  1UXY A;  4BCA A;  5AE3 A;  1DZN A;  3SR6 B;  4PZF A;  5HMR A;  2MBR A;  4BBY A;  2BVH A;  2P3H A;  5FXE A;  5HQX A;  2VFR A;  5FXP A;  1W1M A;  2W3S A;  3FW9 A;  1F0X A;  1N60 C;  1W1Q A;  4JAY A;  4PWC A;  4ML8 A;  2GQU A;  2R8D A;  3EUB 3;  4JB1 A;  1AHZ A;  1W1O A;  2W3R A;  3AMZ A;  5ADZ A;  2VAO A;  3TSJ A;  2QPM A;  1I19 A;  1FFU C;  3KJM A;  2Q4W A;  2BVG A;  3GSY A;  2W54 A;  1RM6 B;  2O3G A;  3LAE A;  3NVW B;  1E8G A;  1W1K A;  3AN1 A;  4OAL A;  5G5G B;  4MLA A;  2Q85 A;  4BC9 A;  3RJA A;  4PVK A;  4PVE A;  3LLB A;  4HG0 A;  3HRD C;  4EC3 A;  2W55 A;  1JRO A;  2AXR A;  4PWB A;  1VAO A;  1N61 C;  2R2Z A;  1JRP A;  3PQB A;  2BVF A;  1FO4 A;  3D2D A;  3S1E A;  3PM9 A;  1W1J A;  2Y4G A;  5I1W A;  5G5H B;  3D2J A;  3NS1 B;  2I0K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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