3PQBA

The crystal structure of pregilvocarcin in complex with gilr, an oxidoreductase that catalyzes the terminal step of gilvocarcin biosynthesis
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
492
structure length
492
Chain Sequence
PFTVGREDPRYIELSHSDNHRFVVEPEEFFLPATPDDVVASLQKAVTEGRGVACRSGGHCGQDFVGTPRRDLVLDLHNLHAIGPAADGAGVRVGSGATVDQVQKALFRRWNAALPLGACSAVGMGGLVAGGGYGPLSRQLGLVVDHLHAVEVAVVDESRTVRLVTARADDTGDLGELFWAHTGGGGGNFGVVTAYEFRSPEHLATEPVGLPRAAGRLHVQKVVFPWAMIDETSFVTVMRRFFEWHERHSEPGSPESSLFATFFVNHVSSGVLQLMVQQDADVDPEGEILARFVASLTEGTGVVGIPRGGVMSWLTGTRYMSQADCGDVMGARSASKSAYHRAAPTDEQLSVLHRHLHADHPGQASYVMFNSYGGEINRRGPSDAAVPQRDSVVKSSWFSAWQDAELDELHLGWLRGLYEEFFAGTGGVPVTGGRTDGCYINYPDADLLDPARNRSGEPWHHLYYKDNYARLRSAKRAWDPLNTFHHSMSIGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Putative oxidoreductase
publication title The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis.
pubmed doi rcsb
source organism Streptomyces griseoflavus
molecule tags Oxidoreductase
total genus 165
structure length 492
sequence length 492
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.465.40 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3pqbA01
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3pqbA02
3TSJA 3PQBA 5L6FA 4XLOA 5I1WA 3FW7A 3D2JA 4PWCA 2BVGA 3HSUA 2BVFA 5K8EA 4PZFA 3W8XA 2Y3RA 3RJ8A 3FW9A 3VTEA 2UUVA 4PVKA 5L6GA 2Y4GA 2IPIA 2BVHA 3FWAA 2Y08A 2WDWA 3RJAA 3GSYA 3TSHA 2Y3SA 3W8WA 4DNSA 2UUUA 1ZR6A 3D2DA 3POPA 4PVJA 5I1VA 3W8ZA 4UD8A 5D79A 4PVEA 4PVHA 4EC3A 3D2HA 3FW8A 5AWVA 2AXRA 4PWBA
chains in the Genus database with same CATH superfamily
1RM6B 2NQWA 3LAEA 3DEDA 3FW7A 3PM9A 2W3SA 4XLOA 5HMRA 2O3GA 2BVGA 3S1DA 5I1WA 3BW7A 2EXRA 3SR6B 1E8FA 2R8DA 5AE2A 1V97A 3AMZA 3NVYB 5AE1A 3FW9A 3HRDC 1N63C 3VTEA 4ZOHB 2Q85A 5L6GA 1W1LA 2IPIA 2BVHA 1AHVA 1E8HA 1FFVC 1N62C 1MBBA 3TSHA 2Y3SA 2GQTA 2W55A 2UUUA 3DQ0A 5I1VA 1JRPA 4PYTA 3FW8A 5AWVA 3LLBA 1W1KA 2AXRA 2PLIA 3S1FA 1AHZA 1VAOA 5FXPA 3C0PA 2RK5A 4PWCA 1W1OA 2BVFA 1DIIA 5K8EA 1DZNA 1QLTA 1WVEA 2Y3RA 3AM9A 1ZXIC 2I0KA 2W3RA 1SB3B 4O95A 1N5XA 2Y4GA 1W1SA 3I99A 2VFRA 3FWAA 2Y08A 2R2ZA 3EUB3 2VFVA 2W54A 3NVZB 5FXDA 4BCAA 5HHZA 1W1JA 4HG0A 2VFTA 3D2DA 4UD8A 1F0XA 4JAYA 1QLUA 1W1RA 1E0YA 1HSKA 4PWBA 5G5GB 3PQBA 1T3QC 1W1QA 5L6FA 4ML8A 3D2JA 2GQUA 1WVFA 1I19A 3HSUA 1UXYA 5ADZA 3W8XA 5FXEA 1N5WC 3NVVB 1AHUA 2P3HA 3TX1A 1JROA 3S1CA 2QKNA 4MLAA 2E3TA 3GSYA 1MBTA 2VFUA 3B9JB 4OALA 1DIQA 4BC7A 4BC9A 4DNSA 3POPA 5D79A 4EC3A 4PVHA 2Q4WA 1FIQB 2P4PA 3S1EA 3TSJA 5AE3A 1W1MA 2PLSA 2VAOA 5G5HB 4PZFA 2YVSA 4BBYA 1N60C 1WYGA 3RJ8A 1E8GA 2UUVA 1FO4A 4PVKA 2OAIA 4JB1A 1FFUC 5HQXA 2P13A 3RJAA 2WDWA 3KJMA 2VFSA 3AN1A 3JS8A 3NS1B 4PVJA 1ZR6A 3W8ZA 2QPMA 1N61C 4PVEA 5FXFA 3ETRB 1VDVA 2MBRA 3D2HA 3NRZB 3NVWB 3W8WA
chains in the Genus database with same CATH topology
1RM6B 2NQWA 3LAEA 3DEDA 3FW7A 3PM9A 2W3SA 4XLOA 5HMRA 2O3GA 2BVGA 3S1DA 5I1WA 3BW7A 2EXRA 3SR6B 1E8FA 2R8DA 5AE2A 1V97A 3AMZA 3NVYB 5AE1A 3FW9A 3HRDC 1N63C 3VTEA 4ZOHB 2Q85A 5L6GA 1W1LA 2IPIA 2BVHA 1AHVA 1E8HA 1FFVC 1N62C 1MBBA 3TSHA 2Y3SA 2GQTA 2W55A 2UUUA 3DQ0A 5I1VA 1JRPA 4PYTA 3FW8A 5AWVA 3LLBA 1W1KA 2AXRA 2PLIA 3S1FA 1AHZA 1VAOA 5FXPA 3C0PA 2RK5A 4PWCA 1W1OA 2BVFA 1DIIA 5K8EA 1DZNA 1QLTA 1WVEA 2Y3RA 3AM9A 1ZXIC 2I0KA 2W3RA 1SB3B 4O95A 1N5XA 2Y4GA 1W1SA 3I99A 2VFRA 3FWAA 2Y08A 2R2ZA 3EUB3 2VFVA 2W54A 3NVZB 5FXDA 4BCAA 5HHZA 1W1JA 4HG0A 2VFTA 3D2DA 4UD8A 1F0XA 4JAYA 1QLUA 1W1RA 1E0YA 1HSKA 4PWBA 5G5GB 3PQBA 1T3QC 1W1QA 5L6FA 4ML8A 3D2JA 2GQUA 1WVFA 1I19A 3HSUA 1UXYA 5ADZA 3W8XA 5FXEA 1N5WC 3NVVB 1AHUA 2P3HA 3TX1A 1JROA 3S1CA 2QKNA 4MLAA 2E3TA 3GSYA 1MBTA 2VFUA 3B9JB 4OALA 1DIQA 4BC7A 4BC9A 4DNSA 3POPA 5D79A 4EC3A 4PVHA 2Q4WA 1FIQB 2P4PA 3S1EA 3TSJA 5AE3A 1W1MA 2PLSA 2VAOA 5G5HB 4PZFA 2YVSA 4BBYA 1N60C 1WYGA 3RJ8A 1E8GA 2UUVA 1FO4A 4PVKA 2OAIA 4JB1A 1FFUC 5HQXA 2P13A 3RJAA 2WDWA 3KJMA 2VFSA 3AN1A 3JS8A 3NS1B 4PVJA 1ZR6A 3W8ZA 2QPMA 1N61C 4PVEA 5FXFA 3ETRB 1VDVA 2MBRA 3D2HA 3NRZB 3NVWB 3W8WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TSJ A;  3PQB A;  5L6F A;  4XLO A;  5I1W A;  3FW7 A;  3D2J A;  4PWC A;  2BVG A;  3HSU A;  2BVF A;  5K8E A;  4PZF A;  3W8X A;  2Y3R A;  3RJ8 A;  3FW9 A;  3VTE A;  2UUV A;  4PVK A;  5L6G A;  2Y4G A;  2IPI A;  2BVH A;  3FWA A;  2Y08 A;  2WDW A;  3RJA A;  3GSY A;  3TSH A;  2Y3S A;  3W8W A;  4DNS A;  2UUU A;  1ZR6 A;  3D2D A;  3POP A;  4PVJ A;  5I1V A;  3W8Z A;  4UD8 A;  5D79 A;  4PVE A;  4PVH A;  4EC3 A;  3D2H A;  3FW8 A;  5AWV A;  2AXR A;  4PWB A; 
#chains in the Genus database with same CATH topology
 1RM6 B;  2NQW A;  3LAE A;  3DED A;  3FW7 A;  3PM9 A;  2W3S A;  4XLO A;  5HMR A;  2O3G A;  2BVG A;  3S1D A;  5I1W A;  3BW7 A;  2EXR A;  3SR6 B;  1E8F A;  2R8D A;  5AE2 A;  1V97 A;  3AMZ A;  3NVY B;  5AE1 A;  3FW9 A;  3HRD C;  1N63 C;  3VTE A;  4ZOH B;  2Q85 A;  5L6G A;  1W1L A;  2IPI A;  2BVH A;  1AHV A;  1E8H A;  1FFV C;  1N62 C;  1MBB A;  3TSH A;  2Y3S A;  2GQT A;  2W55 A;  2UUU A;  3DQ0 A;  5I1V A;  1JRP A;  4PYT A;  3FW8 A;  5AWV A;  3LLB A;  1W1K A;  2AXR A;  2PLI A;  3S1F A;  1AHZ A;  1VAO A;  5FXP A;  3C0P A;  2RK5 A;  4PWC A;  1W1O A;  2BVF A;  1DII A;  5K8E A;  1DZN A;  1QLT A;  1WVE A;  2Y3R A;  3AM9 A;  1ZXI C;  2I0K A;  2W3R A;  1SB3 B;  4O95 A;  1N5X A;  2Y4G A;  1W1S A;  3I99 A;  2VFR A;  3FWA A;  2Y08 A;  2R2Z A;  3EUB 3;  2VFV A;  2W54 A;  3NVZ B;  5FXD A;  4BCA A;  5HHZ A;  1W1J A;  4HG0 A;  2VFT A;  3D2D A;  4UD8 A;  1F0X A;  4JAY A;  1QLU A;  1W1R A;  1E0Y A;  1HSK A;  4PWB A;  5G5G B;  3PQB A;  1T3Q C;  1W1Q A;  5L6F A;  4ML8 A;  3D2J A;  2GQU A;  1WVF A;  1I19 A;  3HSU A;  1UXY A;  5ADZ A;  3W8X A;  5FXE A;  1N5W C;  3NVV B;  1AHU A;  2P3H A;  3TX1 A;  1JRO A;  3S1C A;  2QKN A;  4MLA A;  2E3T A;  3GSY A;  1MBT A;  2VFU A;  3B9J B;  4OAL A;  1DIQ A;  4BC7 A;  4BC9 A;  4DNS A;  3POP A;  5D79 A;  4EC3 A;  4PVH A;  2Q4W A;  1FIQ B;  2P4P A;  3S1E A;  3TSJ A;  5AE3 A;  1W1M A;  2PLS A;  2VAO A;  5G5H B;  4PZF A;  2YVS A;  4BBY A;  1N60 C;  1WYG A;  3RJ8 A;  1E8G A;  2UUV A;  1FO4 A;  4PVK A;  2OAI A;  4JB1 A;  1FFU C;  5HQX A;  2P13 A;  3RJA A;  2WDW A;  3KJM A;  2VFS A;  3AN1 A;  3JS8 A;  3NS1 B;  4PVJ A;  1ZR6 A;  3W8Z A;  2QPM A;  1N61 C;  4PVE A;  5FXF A;  3ETR B;  1VDV A;  2MBR A;  3D2H A;  3NRZ B;  3NVW B;  3W8W A; 
#chains in the Genus database with same CATH homology
 1RM6 B;  2NQW A;  3LAE A;  3DED A;  3FW7 A;  3PM9 A;  2W3S A;  4XLO A;  5HMR A;  2O3G A;  2BVG A;  3S1D A;  5I1W A;  3BW7 A;  2EXR A;  3SR6 B;  1E8F A;  2R8D A;  5AE2 A;  1V97 A;  3AMZ A;  3NVY B;  5AE1 A;  3FW9 A;  3HRD C;  1N63 C;  3VTE A;  4ZOH B;  2Q85 A;  5L6G A;  1W1L A;  2IPI A;  2BVH A;  1AHV A;  1E8H A;  1FFV C;  1N62 C;  1MBB A;  3TSH A;  2Y3S A;  2GQT A;  2W55 A;  2UUU A;  3DQ0 A;  5I1V A;  1JRP A;  4PYT A;  3FW8 A;  5AWV A;  3LLB A;  1W1K A;  2AXR A;  2PLI A;  3S1F A;  1AHZ A;  1VAO A;  5FXP A;  3C0P A;  2RK5 A;  4PWC A;  1W1O A;  2BVF A;  1DII A;  5K8E A;  1DZN A;  1QLT A;  1WVE A;  2Y3R A;  3AM9 A;  1ZXI C;  2I0K A;  2W3R A;  1SB3 B;  4O95 A;  1N5X A;  2Y4G A;  1W1S A;  3I99 A;  2VFR A;  3FWA A;  2Y08 A;  2R2Z A;  3EUB 3;  2VFV A;  2W54 A;  3NVZ B;  5FXD A;  4BCA A;  5HHZ A;  1W1J A;  4HG0 A;  2VFT A;  3D2D A;  4UD8 A;  1F0X A;  4JAY A;  1QLU A;  1W1R A;  1E0Y A;  1HSK A;  4PWB A;  5G5G B;  3PQB A;  1T3Q C;  1W1Q A;  5L6F A;  4ML8 A;  3D2J A;  2GQU A;  1WVF A;  1I19 A;  3HSU A;  1UXY A;  5ADZ A;  3W8X A;  5FXE A;  1N5W C;  3NVV B;  1AHU A;  2P3H A;  3TX1 A;  1JRO A;  3S1C A;  2QKN A;  4MLA A;  2E3T A;  3GSY A;  1MBT A;  2VFU A;  3B9J B;  4OAL A;  1DIQ A;  4BC7 A;  4BC9 A;  4DNS A;  3POP A;  5D79 A;  4EC3 A;  4PVH A;  2Q4W A;  1FIQ B;  2P4P A;  3S1E A;  3TSJ A;  5AE3 A;  1W1M A;  2PLS A;  2VAO A;  5G5H B;  4PZF A;  2YVS A;  4BBY A;  1N60 C;  1WYG A;  3RJ8 A;  1E8G A;  2UUV A;  1FO4 A;  4PVK A;  2OAI A;  4JB1 A;  1FFU C;  5HQX A;  2P13 A;  3RJA A;  2WDW A;  3KJM A;  2VFS A;  3AN1 A;  3JS8 A;  3NS1 B;  4PVJ A;  1ZR6 A;  3W8Z A;  2QPM A;  1N61 C;  4PVE A;  5FXF A;  3ETR B;  1VDV A;  2MBR A;  3D2H A;  3NRZ B;  3NVW B;  3W8W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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