3PVUG

Bovine grk2 in complex with gbetagamma subunits and a selective kinase inhibitor (cmpd101)
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
60
structure length
60
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
molecule tags Transferase/signaling protein/inhibitor
source organism Bos taurus
molecule keywords Beta-adrenergic receptor kinase 1
total genus 13
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2010-12-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 3pvuG00
5KDOG 5HE0G 2BCJG 3KRWG 2PBIA 2TRCG 1OMWG 3CIKG 5HE1G 5HE3G 1GP2G 3KRXG 1TBGE 1GG2G 3PVUG 3PSCG 1B9YB 5HE2G 4MK0G 4KFMG 1B9XB 1XHMB 5TDHG 1GOTG 3SN6G 1A0RG 4PNKG 3AH8G 3PVWG 3V5WG
chains in the Genus database with same CATH superfamily
5KDOG 5HE0G 2BCJG 1HFES 3KRWG 2PBIA 2TRCG 1OMWG 3CIKG 5HE1G 5HE3G 1GP2G 3KRXG 1TBGE 1GG2G 3PVUG 3PSCG 1B9YB 5HE2G 4MK0G 4KFMG 1B9XB 1XHMB 5TDHG 1GOTG 3SN6G 1A0RG 4PNKG 1IOJA 3AH8G 3PVWG 3V5WG
chains in the Genus database with same CATH topology
5KDOG 5HE0G 2BCJG 3KRWG 2PBIA 2TRCG 1OMWG 3CIKG 5HE1G 5HE3G 1GP2G 3KRXG 1TBGE 1GG2G 3PVUG 3PSCG 1B9YB 5HE2G 4MK0G 4KFMG 1B9XB 1XHMB 5TDHG 1GOTG 3SN6G 1A0RG 4PNKG 3AH8G 3PVWG 3V5WG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KDO G;  5HE0 G;  2BCJ G;  3KRW G;  2PBI A;  2TRC G;  1OMW G;  3CIK G;  5HE1 G;  5HE3 G;  1GP2 G;  3KRX G;  1TBG E;  1GG2 G;  3PVU G;  3PSC G;  1B9Y B;  5HE2 G;  4MK0 G;  4KFM G;  1B9X B;  1XHM B;  5TDH G;  1GOT G;  3SN6 G;  1A0R G;  4PNK G;  3AH8 G;  3PVW G;  3V5W G; 
#chains in the Genus database with same CATH topology
 5KDO G;  5HE0 G;  2BCJ G;  1HFE S;  3KRW G;  2PBI A;  2TRC G;  1OMW G;  3CIK G;  5HE1 G;  5HE3 G;  1GP2 G;  3KRX G;  1TBG E;  1GG2 G;  3PVU G;  3PSC G;  1B9Y B;  5HE2 G;  4MK0 G;  4KFM G;  1B9X B;  1XHM B;  5TDH G;  1GOT G;  3SN6 G;  1A0R G;  4PNK G;  1IOJ A;  3AH8 G;  3PVW G;  3V5W G; 
#chains in the Genus database with same CATH homology
 5KDO G;  5HE0 G;  2BCJ G;  3KRW G;  2PBI A;  2TRC G;  1OMW G;  3CIK G;  5HE1 G;  5HE3 G;  1GP2 G;  3KRX G;  1TBG E;  1GG2 G;  3PVU G;  3PSC G;  1B9Y B;  5HE2 G;  4MK0 G;  4KFM G;  1B9X B;  1XHM B;  5TDH G;  1GOT G;  3SN6 G;  1A0R G;  4PNK G;  3AH8 G;  3PVW G;  3V5W G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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