3PVUG

Bovine grk2 in complex with gbetagamma subunits and a selective kinase inhibitor (cmpd101)
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
60
structure length
60
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
molecule keywords Beta-adrenergic receptor kinase 1
molecule tags Transferase/signaling protein/inhibitor
source organism Bos taurus
total genus 13
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2010-12-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 3pvuG00
5HE2G 3PSCG 2PBIA 2TRCG 3V5WG 4KFMG 3SN6G 3KRWG 3CIKG 4PNKG 1XHMB 3KRXG 5HE0G 5HE3G 2BCJG 5KDOG 1OMWG 1GOTG 4MK0G 3PVUG 1B9XB 5TDHG 5HE1G 1GP2G 3AH8G 3PVWG 1B9YB 1GG2G 1TBGE 1A0RG
chains in the Genus database with same CATH superfamily
1HFES 5HE2G 3PSCG 2PBIA 2TRCG 3V5WG 4KFMG 3SN6G 3KRWG 3CIKG 4PNKG 1XHMB 3KRXG 5HE0G 1IOJA 5HE3G 2BCJG 5KDOG 1OMWG 1GOTG 4MK0G 3PVUG 1B9XB 5TDHG 5HE1G 1GP2G 3AH8G 3PVWG 1B9YB 1GG2G 1TBGE 1A0RG
chains in the Genus database with same CATH topology
5HE2G 3PSCG 2PBIA 2TRCG 3V5WG 4KFMG 3SN6G 3KRWG 3CIKG 4PNKG 1XHMB 3KRXG 5HE0G 5HE3G 2BCJG 5KDOG 1OMWG 1GOTG 4MK0G 3PVUG 1B9XB 5TDHG 5HE1G 1GP2G 3AH8G 3PVWG 1B9YB 1GG2G 1TBGE 1A0RG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HE2 G;  3PSC G;  2PBI A;  2TRC G;  3V5W G;  4KFM G;  3SN6 G;  3KRW G;  3CIK G;  4PNK G;  1XHM B;  3KRX G;  5HE0 G;  5HE3 G;  2BCJ G;  5KDO G;  1OMW G;  1GOT G;  4MK0 G;  3PVU G;  1B9X B;  5TDH G;  5HE1 G;  1GP2 G;  3AH8 G;  3PVW G;  1B9Y B;  1GG2 G;  1TBG E;  1A0R G; 
#chains in the Genus database with same CATH topology
 1HFE S;  5HE2 G;  3PSC G;  2PBI A;  2TRC G;  3V5W G;  4KFM G;  3SN6 G;  3KRW G;  3CIK G;  4PNK G;  1XHM B;  3KRX G;  5HE0 G;  1IOJ A;  5HE3 G;  2BCJ G;  5KDO G;  1OMW G;  1GOT G;  4MK0 G;  3PVU G;  1B9X B;  5TDH G;  5HE1 G;  1GP2 G;  3AH8 G;  3PVW G;  1B9Y B;  1GG2 G;  1TBG E;  1A0R G; 
#chains in the Genus database with same CATH homology
 5HE2 G;  3PSC G;  2PBI A;  2TRC G;  3V5W G;  4KFM G;  3SN6 G;  3KRW G;  3CIK G;  4PNK G;  1XHM B;  3KRX G;  5HE0 G;  5HE3 G;  2BCJ G;  5KDO G;  1OMW G;  1GOT G;  4MK0 G;  3PVU G;  1B9X B;  5TDH G;  5HE1 G;  1GP2 G;  3AH8 G;  3PVW G;  1B9Y B;  1GG2 G;  1TBG E;  1A0R G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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