3PVWG

Bovine grk2 in complex with gbetagamma subunits and a selective kinase inhibitor (cmpd103a)
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
60
structure length
60
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
molecule tags Transferase/signaling protein/inhibitor
source organism Bos taurus
molecule keywords Beta-adrenergic receptor kinase 1
total genus 12
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2010-12-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 3pvwG00
3AH8G 1GP2G 1GG2G 5KDOG 1B9XB 5HE2G 5HE1G 3KRXG 1B9YB 5HE3G 3PSCG 3SN6G 3KRWG 2TRCG 1TBGE 2PBIA 1GOTG 1OMWG 5HE0G 3V5WG 1A0RG 5TDHG 4KFMG 1XHMB 2BCJG 3CIKG 4PNKG 4MK0G 3PVUG 3PVWG
chains in the Genus database with same CATH superfamily
3AH8G 1GP2G 1GG2G 5KDOG 3PVUG 1B9XB 5HE2G 1IOJA 5HE1G 3KRXG 5HE3G 3PSCG 3SN6G 3KRWG 2TRCG 1TBGE 2PBIA 1GOTG 1OMWG 5HE0G 3V5WG 1A0RG 5TDHG 4KFMG 1HFES 1XHMB 2BCJG 3CIKG 4PNKG 4MK0G 1B9YB 3PVWG
chains in the Genus database with same CATH topology
3AH8G 1GP2G 1GG2G 5KDOG 1B9XB 5HE2G 5HE1G 3KRXG 1B9YB 5HE3G 3PSCG 3SN6G 3KRWG 2TRCG 1TBGE 2PBIA 1GOTG 1OMWG 5HE0G 3V5WG 1A0RG 5TDHG 4KFMG 1XHMB 2BCJG 3CIKG 4PNKG 4MK0G 3PVUG 3PVWG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AH8 G;  1GP2 G;  1GG2 G;  5KDO G;  1B9X B;  5HE2 G;  5HE1 G;  3KRX G;  1B9Y B;  5HE3 G;  3PSC G;  3SN6 G;  3KRW G;  2TRC G;  1TBG E;  2PBI A;  1GOT G;  1OMW G;  5HE0 G;  3V5W G;  1A0R G;  5TDH G;  4KFM G;  1XHM B;  2BCJ G;  3CIK G;  4PNK G;  4MK0 G;  3PVU G;  3PVW G; 
#chains in the Genus database with same CATH topology
 3AH8 G;  1GP2 G;  1GG2 G;  5KDO G;  3PVU G;  1B9X B;  5HE2 G;  1IOJ A;  5HE1 G;  3KRX G;  5HE3 G;  3PSC G;  3SN6 G;  3KRW G;  2TRC G;  1TBG E;  2PBI A;  1GOT G;  1OMW G;  5HE0 G;  3V5W G;  1A0R G;  5TDH G;  4KFM G;  1HFE S;  1XHM B;  2BCJ G;  3CIK G;  4PNK G;  4MK0 G;  1B9Y B;  3PVW G; 
#chains in the Genus database with same CATH homology
 3AH8 G;  1GP2 G;  1GG2 G;  5KDO G;  1B9X B;  5HE2 G;  5HE1 G;  3KRX G;  1B9Y B;  5HE3 G;  3PSC G;  3SN6 G;  3KRW G;  2TRC G;  1TBG E;  2PBI A;  1GOT G;  1OMW G;  5HE0 G;  3V5W G;  1A0R G;  5TDH G;  4KFM G;  1XHM B;  2BCJ G;  3CIK G;  4PNK G;  4MK0 G;  3PVU G;  3PVW G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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