3Q2ZA

Human squalene synthase in complex with n-[(3r,5s)-7-chloro-5-(2,3-dimethoxyphenyl)-1-neopentyl-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-acetyl]-l-aspartic acid
Total Genus 140
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
140
sequence length
333
structure length
333
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Squalene synthase
publication title Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/transferase inhibitor
total genus 140
structure length 333
sequence length 333
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2010-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3q2zA00
2ZEVA 3BNXA 3TS7A 3ZCDA 5DJPF 5B0MA 5AFXA 1YYUA 1UBWA 3WCJA 5DJRF 5E8KA 2DH4A 2PS8A 3TFPA 1JFAA 5B0LA 3V1VA 4RXCA 3P5RA 2PS5A 3ICMA 4NKFA 5ILIA 3APZA 5JV2F 3KB9A 1V4EA 4MC8A 1YYRA 4OGUA 4MC0A 4MC3A 3OACB 1VG7A 5IL8A 1YV5A 4PVXF 1HXCA 3WCCA 2E92A 3ICKA 4NUAA 3VJBA 1VG3A 4ZQ8A 1YYTA 4KWDA 3KBKA 1EZFA 2ZCOA 3VJ8A 4GA3A 5IL3A 5I1UA 2E94A 2Z52A 4OKMA 2EWGA 3AE0A 3N49F 3WCIA 1N23A 4LOBA 3M00A 1UBYA 4GAXA 4KQUA 3SDRA 3ICZA 2RAHA 3LDWA 5B02A 3EGTA 3LEEA 2OA6A 4RXDA 3CP6A 3PYAA 4GP2A 2ZEUA 5DGSF 3N3DA 2F8ZF 3WC9A 3CC9A 4QXSF 3ACXA 4OMGA 2H8OA 5JA0F 2AZKA 3NPKA 2J5CA 5IM1A 4KFAA 4LFVF 4P0WA 2F7MF 3WCMA 2Q9ZA 3S4JA 2VF6A 4KQSA 5H9DA 4DXJA 4DZWA 1WY0A 3P5PA 3WEJA 1WL1A 3S9VA 4OMHA 3SDTA 3Q30A 4KVDA 5ERNA 3LZ9A 5DZ2A 4KUXA 3N0FA 2J1OA 1RTRA 5B03A 3EZ3A 4LA5A 4LXWA 5B0IA 5HNAA 5JV0F 4EA1A 2AZJA 3AQBB 3ID0A 4E1EA 3WCBA 2F92F 5HN8A 3KRCB 4LUUA 3DYGA 4PVYF 5IMPA 5DHKA 2ONHA 1RQIA 4NFIF 5EATA 2E93A 5IK0A 4F6XA 3KRAA 3RYEA 4WK5A 3KROB 4JXYA 3RBMA 3VJEA 1FPSA 1WL3A 4F62A 4N9UA 5DGMF 3CKEA 1N20A 5A0JA 3WCLA 5DHIA 3KRPB 3OABB 4KK2A 1WKZA 2FTZA 4LPHF 3UCAA 3PYBA 4EA2A 3PDEA 4JZBA 4LZ3A 2PS4A 3WCFA 5IMIA 3LGZB 5B0KA 5ILKA 3P41A 3KRFB 4KPDA 4DWBA 4E9UA 4LPGF 2Z4YA 1YJ4A 1KIYA 4DI5A 2Z7HA 2Z4WA 5HN9A 2E8TA 5IK9A 1VG6A 1YHLA 3VJCA 1ZW5A 3V1XA 2ZCRA 1VG2A 3N3LF 3LMDA 5ILJA 4NG6A 5EROA 3N46F 3SDVA 5IKAA 3EFQA 4LLTA 1YYSA 4DWGA 1HXGA 3LSNA 4LTVA 4XQSF 4XQRF 3WSAA 4DEMF 2F94F 3OYRA 5ILDA 3OACA 2Q9YA 1V4IA 5DW7A 1N22A 1V4HA 2E8VA 5IKHA 4E9ZA 1WL2A 5IK6A 2OPMA 4FJQA 3G4FA 4OKZA 3LK5A 2E8XA 4NFJF 5ILZA 2J1PA 4H5CF 2ZY1A 4K10A 5DIQF 3WJKA 4JYXA 3NPRA 3TFVA 3WEIA 4NFKF 5EAUA 4RNQA 2F89F 3RMGA 1YQ7A 4XQTF 2AEKA 5HN7A 3WCGA 2Z78A 1N1ZA 1YHKA 4JZXA 4RXEA 1YYQA 4RYPA 3LOMA 2OPNA 4H5DF 4LA6A 5B01A 2PS7A 2E8WA 3Q2QA 4KKMA 4KVIA 3N0GA 3P8RA 1V4KA 3WJOA 3DYHA 1HM7A 1RQJA 3W7FA 3ZMBA 2E4OA 2F9KF 5DGNF 4LFEA 3WCDA 1VG4A 5IN8A 3MAVA 1PS1A 2QISA 5IMNA 3ZMCA 5AHUB 3QQVA 4LZCA 3M02A 2Z7IA 3LVSA 3WCEA 1N24A 3N45F 3PH7A 1HX9A 4KQ5A 2P1CA 3NRIA 1DGPA 3ADZA 4Q23A 2FORA 3LJIA 3KRCA 2AELA 3IPIA 2ZCSA 4FP4A 3LLWA 3Q1OA 4LLSA 3WEGA 3KROA 3Q2ZA 3SDQA 3WJNA 5JV1F 2PS6A 5E8LA 3WCAA 3N5HF 3M0GA 3N6KF 4GP1A 5IVGA 3ZL6A 2AZLA 5KSXF 3VJ9A 3QKCA 3KRPA 3OABA 3B7LA 3AQ0A 5C05A 1JFGA 5B0JA 2E95A 4JVJF 3ACWA 4RXAA 3KRFA 3N1WF 3RYWA 4LFGA 2Q80A 1WL0A 3SAEA 2E8UA 3AQCB 5ER8A 3WEHA 3PKOA 2O1OA 2E91A 3MZVA 3ACYA 3N5JF 3ZOUA 5JUZF 4QPFA 2Z4ZA 3M01A 3WEKA 3TFNA 3BNYA 3DYFA 1N21A 2Z4VA 3SDUA 5B00A 3LGKA 2OGDA 4L2XF 2I19A 1HM4A 2Z4XA 5AYPA 5E8HA 5A0KA 1KIZA 1HXAA 3VJDA 2E90A 4JXNA 3V66A 3WE9A 3G4DA 1DI1A 4N1ZF 5ERMA 2ZCQA 3WEFA 4KVYA 3P8LA 5CG5A 1UBXA 4H5EF 3LG5A 4HD1A 4P0XA 5ILYA 3KRAB 2AETA 3WCHA 4LIXA 5AELA 4EA0A 5A0IA 4NKEA 3TC1A 2ONGA 4UMJA 3VJAA 2Q58A 5ILHA 4KPJA 1N1BA 4LZ0A 5EASA 1V4JA 4F6VA 4KVWA 1YHMA 3M9UA 4LTZA 3NF2A 3IBAA 4DHDA 2Z50A 4P0VA 5CG6A 3N1VF 1UBVA 2F8CF 3ICNA 3WSBA 5DJVF 3ASXA 1WMWA
chains in the Genus database with same CATH superfamily
2ZEVA 3BNXA 3TS7A 3ZCDA 5DJPF 5B0MA 5AFXA 1YYUA 1UBWA 3WCJA 5DJRF 5E8KA 2DH4A 2PS8A 3TFPA 1JFAA 5B0LA 3V1VA 4RXCA 3P5RA 2PS5A 3ICMA 4NKFA 5ILIA 3APZA 5JV2F 3KB9A 1V4EA 4MC8A 1YYRA 4OGUA 4MC0A 4MC3A 3OACB 1VG7A 5IL8A 1YV5A 4PVXF 1HXCA 3WCCA 2E92A 3ICKA 4NUAA 3VJBA 1VG3A 4ZQ8A 1YYTA 4KWDA 3KBKA 1EZFA 2ZCOA 3VJ8A 4GA3A 5IL3A 5I1UA 2E94A 2Z52A 4OKMA 2EWGA 3AE0A 3N49F 3WCIA 1N23A 4LOBA 3M00A 1UBYA 4GAXA 4KQUA 3SDRA 3ICZA 2RAHA 3LDWA 5B02A 3EGTA 3LEEA 2OA6A 4RXDA 3CP6A 3PYAA 4GP2A 2ZEUA 5DGSF 3N3DA 2F8ZF 3WC9A 3CC9A 4QXSF 3ACXA 4OMGA 2H8OA 5JA0F 2AZKA 3NPKA 2J5CA 5IM1A 4KFAA 4LFVF 4P0WA 2F7MF 3WCMA 2Q9ZA 3S4JA 2VF6A 4KQSA 5H9DA 4DXJA 4DZWA 1WY0A 3P5PA 3WEJA 1WL1A 3S9VA 4OMHA 3SDTA 3Q30A 4KVDA 5ERNA 3LZ9A 5DZ2A 4KUXA 3N0FA 2J1OA 1RTRA 5B03A 3EZ3A 4LA5A 4LXWA 5B0IA 5HNAA 5JV0F 4EA1A 2AZJA 3AQBB 3ID0A 4E1EA 3WCBA 2F92F 5HN8A 3KRCB 4LUUA 3DYGA 4PVYF 5IMPA 5DHKA 2ONHA 1RQIA 4NFIF 5EATA 2E93A 5IK0A 4F6XA 3KRAA 3RYEA 4WK5A 3KROB 4JXYA 3RBMA 3VJEA 1FPSA 1WL3A 4F62A 4N9UA 5DGMF 3CKEA 1N20A 5A0JA 3WCLA 5DHIA 3KRPB 3OABB 4KK2A 1WKZA 2FTZA 4LPHF 3UCAA 3PYBA 4EA2A 3PDEA 4JZBA 4LZ3A 2PS4A 3WCFA 5IMIA 3LGZB 5B0KA 5ILKA 3P41A 3KRFB 4KPDA 4DWBA 4E9UA 4LPGF 2Z4YA 1YJ4A 1KIYA 4DI5A 2Z7HA 2Z4WA 5HN9A 2E8TA 5IK9A 1VG6A 1YHLA 3VJCA 1ZW5A 3V1XA 2ZCRA 1VG2A 3N3LF 3LMDA 5ILJA 4NG6A 5EROA 3N46F 3SDVA 5IKAA 3EFQA 4LLTA 1YYSA 4DWGA 1HXGA 3LSNA 4LTVA 4XQSF 4XQRF 3WSAA 4DEMF 2F94F 3OYRA 5ILDA 3OACA 2Q9YA 1V4IA 5DW7A 1N22A 1V4HA 2E8VA 5IKHA 4E9ZA 1WL2A 5IK6A 2OPMA 4FJQA 3G4FA 4OKZA 3LK5A 2E8XA 4NFJF 5ILZA 2J1PA 4H5CF 2ZY1A 4K10A 5DIQF 3WJKA 4JYXA 3NPRA 3TFVA 3WEIA 4NFKF 5EAUA 4RNQA 2F89F 3RMGA 1YQ7A 4XQTF 2AEKA 5HN7A 3WCGA 2Z78A 1N1ZA 1YHKA 4JZXA 4RXEA 1YYQA 4RYPA 3LOMA 2OPNA 4H5DF 4LA6A 5B01A 2PS7A 2E8WA 3Q2QA 4KKMA 4KVIA 3N0GA 3P8RA 1V4KA 3WJOA 3DYHA 1HM7A 1RQJA 3W7FA 3ZMBA 2E4OA 2F9KF 5DGNF 4LFEA 3WCDA 1VG4A 5IN8A 3MAVA 1PS1A 2QISA 5IMNA 3ZMCA 5AHUB 3QQVA 4LZCA 3M02A 2Z7IA 3LVSA 3WCEA 1N24A 3N45F 3PH7A 1HX9A 4KQ5A 2P1CA 3NRIA 1DGPA 3ADZA 4Q23A 2FORA 3LJIA 3KRCA 2AELA 3IPIA 2ZCSA 4FP4A 3LLWA 3Q1OA 4LLSA 3WEGA 3KROA 3Q2ZA 3SDQA 3WJNA 5JV1F 2PS6A 5E8LA 3WCAA 3N5HF 3M0GA 3N6KF 4GP1A 5IVGA 3ZL6A 2AZLA 5KSXF 3VJ9A 3QKCA 3KRPA 3OABA 3B7LA 3AQ0A 5C05A 1JFGA 5B0JA 2E95A 4JVJF 3ACWA 4RXAA 3KRFA 3N1WF 3RYWA 4LFGA 2Q80A 1WL0A 3SAEA 2E8UA 3AQCB 5ER8A 3WEHA 3PKOA 2O1OA 2E91A 3MZVA 3ACYA 3N5JF 3ZOUA 5JUZF 4QPFA 2Z4ZA 3M01A 3WEKA 3TFNA 3BNYA 3DYFA 1N21A 2Z4VA 3SDUA 5B00A 3LGKA 2OGDA 4L2XF 2I19A 1HM4A 2Z4XA 5AYPA 5E8HA 5A0KA 1KIZA 1HXAA 3VJDA 2E90A 4JXNA 3V66A 3WE9A 3G4DA 1DI1A 4N1ZF 5ERMA 2ZCQA 3WEFA 4KVYA 3P8LA 5CG5A 1UBXA 4H5EF 3LG5A 4HD1A 4P0XA 5ILYA 3KRAB 2AETA 3WCHA 4LIXA 5AELA 4EA0A 5A0IA 4NKEA 3TC1A 2ONGA 4UMJA 3VJAA 2Q58A 5ILHA 4KPJA 1N1BA 4LZ0A 5EASA 1V4JA 4F6VA 4KVWA 1YHMA 3M9UA 4LTZA 3NF2A 3IBAA 4DHDA 2Z50A 4P0VA 5CG6A 3N1VF 1UBVA 2F8CF 3ICNA 3WSBA 5DJVF 3ASXA 1WMWA
chains in the Genus database with same CATH topology
2ZEVA 3BNXA 3TS7A 3ZCDA 5DJPF 5B0MA 5AFXA 1YYUA 1UBWA 3WCJA 5DJRF 5E8KA 2DH4A 2PS8A 3TFPA 1JFAA 5B0LA 3V1VA 4RXCA 3P5RA 2PS5A 3ICMA 4NKFA 5ILIA 3APZA 5JV2F 3KB9A 1V4EA 4MC8A 1YYRA 4OGUA 4MC0A 4MC3A 3OACB 1VG7A 5IL8A 1YV5A 4PVXF 1HXCA 3WCCA 2E92A 3ICKA 4NUAA 3VJBA 1VG3A 4ZQ8A 1YYTA 4KWDA 3KBKA 1EZFA 2ZCOA 3VJ8A 4GA3A 5IL3A 5I1UA 2E94A 2Z52A 4OKMA 2EWGA 3AE0A 3N49F 3WCIA 1N23A 4LOBA 3M00A 1UBYA 4GAXA 4KQUA 3SDRA 3ICZA 2RAHA 3LDWA 5B02A 3EGTA 3LEEA 2OA6A 4RXDA 3CP6A 3PYAA 4GP2A 2ZEUA 5DGSF 3N3DA 2F8ZF 3WC9A 3CC9A 4QXSF 3ACXA 4OMGA 2H8OA 5JA0F 2AZKA 3NPKA 2J5CA 5IM1A 4KFAA 4LFVF 4P0WA 2F7MF 3WCMA 2Q9ZA 3S4JA 2VF6A 4KQSA 5H9DA 4DXJA 4DZWA 1WY0A 3P5PA 3WEJA 1WL1A 3S9VA 4OMHA 3SDTA 3Q30A 4KVDA 5ERNA 3LZ9A 5DZ2A 4KUXA 3N0FA 2J1OA 1RTRA 5B03A 3EZ3A 4LA5A 4LXWA 5B0IA 5HNAA 5JV0F 4EA1A 2AZJA 3AQBB 3ID0A 4E1EA 3WCBA 2F92F 5HN8A 3KRCB 4LUUA 3DYGA 4PVYF 5IMPA 5DHKA 2ONHA 1RQIA 4NFIF 5EATA 2E93A 5IK0A 4F6XA 3KRAA 3RYEA 4WK5A 3KROB 4JXYA 3RBMA 3VJEA 1FPSA 1WL3A 4F62A 4N9UA 5DGMF 3CKEA 1N20A 5A0JA 3WCLA 5DHIA 3KRPB 3OABB 4KK2A 1WKZA 2FTZA 4LPHF 3UCAA 3PYBA 4EA2A 3PDEA 4JZBA 4LZ3A 2PS4A 3WCFA 5IMIA 3LGZB 5B0KA 5ILKA 3P41A 3KRFB 4KPDA 4DWBA 4E9UA 4LPGF 2Z4YA 1YJ4A 1KIYA 4DI5A 2Z7HA 2Z4WA 5HN9A 2E8TA 5IK9A 1VG6A 1YHLA 3VJCA 1ZW5A 3V1XA 2ZCRA 1VG2A 3N3LF 3LMDA 5ILJA 4NG6A 5EROA 3N46F 3SDVA 5IKAA 3EFQA 4LLTA 1YYSA 4DWGA 1HXGA 3LSNA 4LTVA 4XQSF 4XQRF 3WSAA 4DEMF 2F94F 3OYRA 5ILDA 3OACA 2Q9YA 1V4IA 5DW7A 1N22A 1V4HA 2E8VA 5IKHA 4E9ZA 1WL2A 5IK6A 2OPMA 4FJQA 3G4FA 4OKZA 3LK5A 2E8XA 4NFJF 5ILZA 2J1PA 4H5CF 2ZY1A 4K10A 5DIQF 3WJKA 4JYXA 3NPRA 3TFVA 3WEIA 4NFKF 5EAUA 4RNQA 2F89F 3RMGA 1YQ7A 4XQTF 2AEKA 5HN7A 3WCGA 2Z78A 1N1ZA 1YHKA 4JZXA 4RXEA 1YYQA 4RYPA 3LOMA 2OPNA 4H5DF 4LA6A 5B01A 2PS7A 2E8WA 3Q2QA 4KKMA 4KVIA 3N0GA 3P8RA 1V4KA 3WJOA 3DYHA 1HM7A 1RQJA 3W7FA 3ZMBA 2E4OA 2F9KF 5DGNF 4LFEA 3WCDA 1VG4A 5IN8A 3MAVA 1PS1A 2QISA 5IMNA 3ZMCA 5AHUB 3QQVA 4LZCA 3M02A 2Z7IA 3LVSA 3WCEA 1N24A 3N45F 3PH7A 1HX9A 4KQ5A 2P1CA 3NRIA 1DGPA 3ADZA 4Q23A 2FORA 3LJIA 3KRCA 2AELA 3IPIA 2ZCSA 4FP4A 3LLWA 3Q1OA 4LLSA 3WEGA 3KROA 3Q2ZA 3SDQA 3WJNA 5JV1F 2PS6A 5E8LA 3WCAA 3N5HF 3M0GA 3N6KF 4GP1A 5IVGA 3ZL6A 2AZLA 5KSXF 3VJ9A 3QKCA 3KRPA 3OABA 3B7LA 3AQ0A 5C05A 1JFGA 5B0JA 2E95A 4JVJF 3ACWA 4RXAA 3KRFA 3N1WF 3RYWA 4LFGA 2Q80A 1WL0A 3SAEA 2E8UA 3AQCB 5ER8A 3WEHA 3PKOA 2O1OA 2E91A 3MZVA 3ACYA 3N5JF 3ZOUA 5JUZF 4QPFA 2Z4ZA 3M01A 3WEKA 3TFNA 3BNYA 3DYFA 1N21A 2Z4VA 3SDUA 5B00A 3LGKA 2OGDA 4L2XF 2I19A 1HM4A 2Z4XA 5AYPA 5E8HA 5A0KA 1KIZA 1HXAA 3VJDA 2E90A 4JXNA 3V66A 3WE9A 3G4DA 1DI1A 4N1ZF 5ERMA 2ZCQA 3WEFA 4KVYA 3P8LA 5CG5A 1UBXA 4H5EF 3LG5A 4HD1A 4P0XA 5ILYA 3KRAB 2AETA 3WCHA 4LIXA 5AELA 4EA0A 5A0IA 4NKEA 3TC1A 2ONGA 4UMJA 3VJAA 2Q58A 5ILHA 4KPJA 1N1BA 4LZ0A 5EASA 1V4JA 4F6VA 4KVWA 1YHMA 3M9UA 4LTZA 3NF2A 3IBAA 4DHDA 2Z50A 4P0VA 5CG6A 3N1VF 1UBVA 2F8CF 3ICNA 3WSBA 5DJVF 3ASXA 1WMWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZEV A;  3BNX A;  3TS7 A;  3ZCD A;  5DJP F;  5B0M A;  5AFX A;  1YYU A;  1UBW A;  3WCJ A;  5DJR F;  5E8K A;  2DH4 A;  2PS8 A;  3TFP A;  1JFA A;  5B0L A;  3V1V A;  4RXC A;  3P5R A;  2PS5 A;  3ICM A;  4NKF A;  5ILI A;  3APZ A;  5JV2 F;  3KB9 A;  1V4E A;  4MC8 A;  1YYR A;  4OGU A;  4MC0 A;  4MC3 A;  3OAC B;  1VG7 A;  5IL8 A;  1YV5 A;  4PVX F;  1HXC A;  3WCC A;  2E92 A;  3ICK A;  4NUA A;  3VJB A;  1VG3 A;  4ZQ8 A;  1YYT A;  4KWD A;  3KBK A;  1EZF A;  2ZCO A;  3VJ8 A;  4GA3 A;  5IL3 A;  5I1U A;  2E94 A;  2Z52 A;  4OKM A;  2EWG A;  3AE0 A;  3N49 F;  3WCI A;  1N23 A;  4LOB A;  3M00 A;  1UBY A;  4GAX A;  4KQU A;  3SDR A;  3ICZ A;  2RAH A;  3LDW A;  5B02 A;  3EGT A;  3LEE A;  2OA6 A;  4RXD A;  3CP6 A;  3PYA A;  4GP2 A;  2ZEU A;  5DGS F;  3N3D A;  2F8Z F;  3WC9 A;  3CC9 A;  4QXS F;  3ACX A;  4OMG A;  2H8O A;  5JA0 F;  2AZK A;  3NPK A;  2J5C A;  5IM1 A;  4KFA A;  4LFV F;  4P0W A;  2F7M F;  3WCM A;  2Q9Z A;  3S4J A;  2VF6 A;  4KQS A;  5H9D A;  4DXJ A;  4DZW A;  1WY0 A;  3P5P A;  3WEJ A;  1WL1 A;  3S9V A;  4OMH A;  3SDT A;  3Q30 A;  4KVD A;  5ERN A;  3LZ9 A;  5DZ2 A;  4KUX A;  3N0F A;  2J1O A;  1RTR A;  5B03 A;  3EZ3 A;  4LA5 A;  4LXW A;  5B0I A;  5HNA A;  5JV0 F;  4EA1 A;  2AZJ A;  3AQB B;  3ID0 A;  4E1E A;  3WCB A;  2F92 F;  5HN8 A;  3KRC B;  4LUU A;  3DYG A;  4PVY F;  5IMP A;  5DHK A;  2ONH A;  1RQI A;  4NFI F;  5EAT A;  2E93 A;  5IK0 A;  4F6X A;  3KRA A;  3RYE A;  4WK5 A;  3KRO B;  4JXY A;  3RBM A;  3VJE A;  1FPS A;  1WL3 A;  4F62 A;  4N9U A;  5DGM F;  3CKE A;  1N20 A;  5A0J A;  3WCL A;  5DHI A;  3KRP B;  3OAB B;  4KK2 A;  1WKZ A;  2FTZ A;  4LPH F;  3UCA A;  3PYB A;  4EA2 A;  3PDE A;  4JZB A;  4LZ3 A;  2PS4 A;  3WCF A;  5IMI A;  3LGZ B;  5B0K A;  5ILK A;  3P41 A;  3KRF B;  4KPD A;  4DWB A;  4E9U A;  4LPG F;  2Z4Y A;  1YJ4 A;  1KIY A;  4DI5 A;  2Z7H A;  2Z4W A;  5HN9 A;  2E8T A;  5IK9 A;  1VG6 A;  1YHL A;  3VJC A;  1ZW5 A;  3V1X A;  2ZCR A;  1VG2 A;  3N3L F;  3LMD A;  5ILJ A;  4NG6 A;  5ERO A;  3N46 F;  3SDV A;  5IKA A;  3EFQ A;  4LLT A;  1YYS A;  4DWG A;  1HXG A;  3LSN A;  4LTV A;  4XQS F;  4XQR F;  3WSA A;  4DEM F;  2F94 F;  3OYR A;  5ILD A;  3OAC A;  2Q9Y A;  1V4I A;  5DW7 A;  1N22 A;  1V4H A;  2E8V A;  5IKH A;  4E9Z A;  1WL2 A;  5IK6 A;  2OPM A;  4FJQ A;  3G4F A;  4OKZ A;  3LK5 A;  2E8X A;  4NFJ F;  5ILZ A;  2J1P A;  4H5C F;  2ZY1 A;  4K10 A;  5DIQ F;  3WJK A;  4JYX A;  3NPR A;  3TFV A;  3WEI A;  4NFK F;  5EAU A;  4RNQ A;  2F89 F;  3RMG A;  1YQ7 A;  4XQT F;  2AEK A;  5HN7 A;  3WCG A;  2Z78 A;  1N1Z A;  1YHK A;  4JZX A;  4RXE A;  1YYQ A;  4RYP A;  3LOM A;  2OPN A;  4H5D F;  4LA6 A;  5B01 A;  2PS7 A;  2E8W A;  3Q2Q A;  4KKM A;  4KVI A;  3N0G A;  3P8R A;  1V4K A;  3WJO A;  3DYH A;  1HM7 A;  1RQJ A;  3W7F A;  3ZMB A;  2E4O A;  2F9K F;  5DGN F;  4LFE A;  3WCD A;  1VG4 A;  5IN8 A;  3MAV A;  1PS1 A;  2QIS A;  5IMN A;  3ZMC A;  5AHU B;  3QQV A;  4LZC A;  3M02 A;  2Z7I A;  3LVS A;  3WCE A;  1N24 A;  3N45 F;  3PH7 A;  1HX9 A;  4KQ5 A;  2P1C A;  3NRI A;  1DGP A;  3ADZ A;  4Q23 A;  2FOR A;  3LJI A;  3KRC A;  2AEL A;  3IPI A;  2ZCS A;  4FP4 A;  3LLW A;  3Q1O A;  4LLS A;  3WEG A;  3KRO A;  3Q2Z A;  3SDQ A;  3WJN A;  5JV1 F;  2PS6 A;  5E8L A;  3WCA A;  3N5H F;  3M0G A;  3N6K F;  4GP1 A;  5IVG A;  3ZL6 A;  2AZL A;  5KSX F;  3VJ9 A;  3QKC A;  3KRP A;  3OAB A;  3B7L A;  3AQ0 A;  5C05 A;  1JFG A;  5B0J A;  2E95 A;  4JVJ F;  3ACW A;  4RXA A;  3KRF A;  3N1W F;  3RYW A;  4LFG A;  2Q80 A;  1WL0 A;  3SAE A;  2E8U A;  3AQC B;  5ER8 A;  3WEH A;  3PKO A;  2O1O A;  2E91 A;  3MZV A;  3ACY A;  3N5J F;  3ZOU A;  5JUZ F;  4QPF A;  2Z4Z A;  3M01 A;  3WEK A;  3TFN A;  3BNY A;  3DYF A;  1N21 A;  2Z4V A;  3SDU A;  5B00 A;  3LGK A;  2OGD A;  4L2X F;  2I19 A;  1HM4 A;  2Z4X A;  5AYP A;  5E8H A;  5A0K A;  1KIZ A;  1HXA A;  3VJD A;  2E90 A;  4JXN A;  3V66 A;  3WE9 A;  3G4D A;  1DI1 A;  4N1Z F;  5ERM A;  2ZCQ A;  3WEF A;  4KVY A;  3P8L A;  5CG5 A;  1UBX A;  4H5E F;  3LG5 A;  4HD1 A;  4P0X A;  5ILY A;  3KRA B;  2AET A;  3WCH A;  4LIX A;  5AEL A;  4EA0 A;  5A0I A;  4NKE A;  3TC1 A;  2ONG A;  4UMJ A;  3VJA A;  2Q58 A;  5ILH A;  4KPJ A;  1N1B A;  4LZ0 A;  5EAS A;  1V4J A;  4F6V A;  4KVW A;  1YHM A;  3M9U A;  4LTZ A;  3NF2 A;  3IBA A;  4DHD A;  2Z50 A;  4P0V A;  5CG6 A;  3N1V F;  1UBV A;  2F8C F;  3ICN A;  3WSB A;  5DJV F;  3ASX A;  1WMW A; 
#chains in the Genus database with same CATH topology
 2ZEV A;  3BNX A;  3TS7 A;  3ZCD A;  5DJP F;  5B0M A;  5AFX A;  1YYU A;  1UBW A;  3WCJ A;  5DJR F;  5E8K A;  2DH4 A;  2PS8 A;  3TFP A;  1JFA A;  5B0L A;  3V1V A;  4RXC A;  3P5R A;  2PS5 A;  3ICM A;  4NKF A;  5ILI A;  3APZ A;  5JV2 F;  3KB9 A;  1V4E A;  4MC8 A;  1YYR A;  4OGU A;  4MC0 A;  4MC3 A;  3OAC B;  1VG7 A;  5IL8 A;  1YV5 A;  4PVX F;  1HXC A;  3WCC A;  2E92 A;  3ICK A;  4NUA A;  3VJB A;  1VG3 A;  4ZQ8 A;  1YYT A;  4KWD A;  3KBK A;  1EZF A;  2ZCO A;  3VJ8 A;  4GA3 A;  5IL3 A;  5I1U A;  2E94 A;  2Z52 A;  4OKM A;  2EWG A;  3AE0 A;  3N49 F;  3WCI A;  1N23 A;  4LOB A;  3M00 A;  1UBY A;  4GAX A;  4KQU A;  3SDR A;  3ICZ A;  2RAH A;  3LDW A;  5B02 A;  3EGT A;  3LEE A;  2OA6 A;  4RXD A;  3CP6 A;  3PYA A;  4GP2 A;  2ZEU A;  5DGS F;  3N3D A;  2F8Z F;  3WC9 A;  3CC9 A;  4QXS F;  3ACX A;  4OMG A;  2H8O A;  5JA0 F;  2AZK A;  3NPK A;  2J5C A;  5IM1 A;  4KFA A;  4LFV F;  4P0W A;  2F7M F;  3WCM A;  2Q9Z A;  3S4J A;  2VF6 A;  4KQS A;  5H9D A;  4DXJ A;  4DZW A;  1WY0 A;  3P5P A;  3WEJ A;  1WL1 A;  3S9V A;  4OMH A;  3SDT A;  3Q30 A;  4KVD A;  5ERN A;  3LZ9 A;  5DZ2 A;  4KUX A;  3N0F A;  2J1O A;  1RTR A;  5B03 A;  3EZ3 A;  4LA5 A;  4LXW A;  5B0I A;  5HNA A;  5JV0 F;  4EA1 A;  2AZJ A;  3AQB B;  3ID0 A;  4E1E A;  3WCB A;  2F92 F;  5HN8 A;  3KRC B;  4LUU A;  3DYG A;  4PVY F;  5IMP A;  5DHK A;  2ONH A;  1RQI A;  4NFI F;  5EAT A;  2E93 A;  5IK0 A;  4F6X A;  3KRA A;  3RYE A;  4WK5 A;  3KRO B;  4JXY A;  3RBM A;  3VJE A;  1FPS A;  1WL3 A;  4F62 A;  4N9U A;  5DGM F;  3CKE A;  1N20 A;  5A0J A;  3WCL A;  5DHI A;  3KRP B;  3OAB B;  4KK2 A;  1WKZ A;  2FTZ A;  4LPH F;  3UCA A;  3PYB A;  4EA2 A;  3PDE A;  4JZB A;  4LZ3 A;  2PS4 A;  3WCF A;  5IMI A;  3LGZ B;  5B0K A;  5ILK A;  3P41 A;  3KRF B;  4KPD A;  4DWB A;  4E9U A;  4LPG F;  2Z4Y A;  1YJ4 A;  1KIY A;  4DI5 A;  2Z7H A;  2Z4W A;  5HN9 A;  2E8T A;  5IK9 A;  1VG6 A;  1YHL A;  3VJC A;  1ZW5 A;  3V1X A;  2ZCR A;  1VG2 A;  3N3L F;  3LMD A;  5ILJ A;  4NG6 A;  5ERO A;  3N46 F;  3SDV A;  5IKA A;  3EFQ A;  4LLT A;  1YYS A;  4DWG A;  1HXG A;  3LSN A;  4LTV A;  4XQS F;  4XQR F;  3WSA A;  4DEM F;  2F94 F;  3OYR A;  5ILD A;  3OAC A;  2Q9Y A;  1V4I A;  5DW7 A;  1N22 A;  1V4H A;  2E8V A;  5IKH A;  4E9Z A;  1WL2 A;  5IK6 A;  2OPM A;  4FJQ A;  3G4F A;  4OKZ A;  3LK5 A;  2E8X A;  4NFJ F;  5ILZ A;  2J1P A;  4H5C F;  2ZY1 A;  4K10 A;  5DIQ F;  3WJK A;  4JYX A;  3NPR A;  3TFV A;  3WEI A;  4NFK F;  5EAU A;  4RNQ A;  2F89 F;  3RMG A;  1YQ7 A;  4XQT F;  2AEK A;  5HN7 A;  3WCG A;  2Z78 A;  1N1Z A;  1YHK A;  4JZX A;  4RXE A;  1YYQ A;  4RYP A;  3LOM A;  2OPN A;  4H5D F;  4LA6 A;  5B01 A;  2PS7 A;  2E8W A;  3Q2Q A;  4KKM A;  4KVI A;  3N0G A;  3P8R A;  1V4K A;  3WJO A;  3DYH A;  1HM7 A;  1RQJ A;  3W7F A;  3ZMB A;  2E4O A;  2F9K F;  5DGN F;  4LFE A;  3WCD A;  1VG4 A;  5IN8 A;  3MAV A;  1PS1 A;  2QIS A;  5IMN A;  3ZMC A;  5AHU B;  3QQV A;  4LZC A;  3M02 A;  2Z7I A;  3LVS A;  3WCE A;  1N24 A;  3N45 F;  3PH7 A;  1HX9 A;  4KQ5 A;  2P1C A;  3NRI A;  1DGP A;  3ADZ A;  4Q23 A;  2FOR A;  3LJI A;  3KRC A;  2AEL A;  3IPI A;  2ZCS A;  4FP4 A;  3LLW A;  3Q1O A;  4LLS A;  3WEG A;  3KRO A;  3Q2Z A;  3SDQ A;  3WJN A;  5JV1 F;  2PS6 A;  5E8L A;  3WCA A;  3N5H F;  3M0G A;  3N6K F;  4GP1 A;  5IVG A;  3ZL6 A;  2AZL A;  5KSX F;  3VJ9 A;  3QKC A;  3KRP A;  3OAB A;  3B7L A;  3AQ0 A;  5C05 A;  1JFG A;  5B0J A;  2E95 A;  4JVJ F;  3ACW A;  4RXA A;  3KRF A;  3N1W F;  3RYW A;  4LFG A;  2Q80 A;  1WL0 A;  3SAE A;  2E8U A;  3AQC B;  5ER8 A;  3WEH A;  3PKO A;  2O1O A;  2E91 A;  3MZV A;  3ACY A;  3N5J F;  3ZOU A;  5JUZ F;  4QPF A;  2Z4Z A;  3M01 A;  3WEK A;  3TFN A;  3BNY A;  3DYF A;  1N21 A;  2Z4V A;  3SDU A;  5B00 A;  3LGK A;  2OGD A;  4L2X F;  2I19 A;  1HM4 A;  2Z4X A;  5AYP A;  5E8H A;  5A0K A;  1KIZ A;  1HXA A;  3VJD A;  2E90 A;  4JXN A;  3V66 A;  3WE9 A;  3G4D A;  1DI1 A;  4N1Z F;  5ERM A;  2ZCQ A;  3WEF A;  4KVY A;  3P8L A;  5CG5 A;  1UBX A;  4H5E F;  3LG5 A;  4HD1 A;  4P0X A;  5ILY A;  3KRA B;  2AET A;  3WCH A;  4LIX A;  5AEL A;  4EA0 A;  5A0I A;  4NKE A;  3TC1 A;  2ONG A;  4UMJ A;  3VJA A;  2Q58 A;  5ILH A;  4KPJ A;  1N1B A;  4LZ0 A;  5EAS A;  1V4J A;  4F6V A;  4KVW A;  1YHM A;  3M9U A;  4LTZ A;  3NF2 A;  3IBA A;  4DHD A;  2Z50 A;  4P0V A;  5CG6 A;  3N1V F;  1UBV A;  2F8C F;  3ICN A;  3WSB A;  5DJV F;  3ASX A;  1WMW A; 
#chains in the Genus database with same CATH homology
 2ZEV A;  3BNX A;  3TS7 A;  3ZCD A;  5DJP F;  5B0M A;  5AFX A;  1YYU A;  1UBW A;  3WCJ A;  5DJR F;  5E8K A;  2DH4 A;  2PS8 A;  3TFP A;  1JFA A;  5B0L A;  3V1V A;  4RXC A;  3P5R A;  2PS5 A;  3ICM A;  4NKF A;  5ILI A;  3APZ A;  5JV2 F;  3KB9 A;  1V4E A;  4MC8 A;  1YYR A;  4OGU A;  4MC0 A;  4MC3 A;  3OAC B;  1VG7 A;  5IL8 A;  1YV5 A;  4PVX F;  1HXC A;  3WCC A;  2E92 A;  3ICK A;  4NUA A;  3VJB A;  1VG3 A;  4ZQ8 A;  1YYT A;  4KWD A;  3KBK A;  1EZF A;  2ZCO A;  3VJ8 A;  4GA3 A;  5IL3 A;  5I1U A;  2E94 A;  2Z52 A;  4OKM A;  2EWG A;  3AE0 A;  3N49 F;  3WCI A;  1N23 A;  4LOB A;  3M00 A;  1UBY A;  4GAX A;  4KQU A;  3SDR A;  3ICZ A;  2RAH A;  3LDW A;  5B02 A;  3EGT A;  3LEE A;  2OA6 A;  4RXD A;  3CP6 A;  3PYA A;  4GP2 A;  2ZEU A;  5DGS F;  3N3D A;  2F8Z F;  3WC9 A;  3CC9 A;  4QXS F;  3ACX A;  4OMG A;  2H8O A;  5JA0 F;  2AZK A;  3NPK A;  2J5C A;  5IM1 A;  4KFA A;  4LFV F;  4P0W A;  2F7M F;  3WCM A;  2Q9Z A;  3S4J A;  2VF6 A;  4KQS A;  5H9D A;  4DXJ A;  4DZW A;  1WY0 A;  3P5P A;  3WEJ A;  1WL1 A;  3S9V A;  4OMH A;  3SDT A;  3Q30 A;  4KVD A;  5ERN A;  3LZ9 A;  5DZ2 A;  4KUX A;  3N0F A;  2J1O A;  1RTR A;  5B03 A;  3EZ3 A;  4LA5 A;  4LXW A;  5B0I A;  5HNA A;  5JV0 F;  4EA1 A;  2AZJ A;  3AQB B;  3ID0 A;  4E1E A;  3WCB A;  2F92 F;  5HN8 A;  3KRC B;  4LUU A;  3DYG A;  4PVY F;  5IMP A;  5DHK A;  2ONH A;  1RQI A;  4NFI F;  5EAT A;  2E93 A;  5IK0 A;  4F6X A;  3KRA A;  3RYE A;  4WK5 A;  3KRO B;  4JXY A;  3RBM A;  3VJE A;  1FPS A;  1WL3 A;  4F62 A;  4N9U A;  5DGM F;  3CKE A;  1N20 A;  5A0J A;  3WCL A;  5DHI A;  3KRP B;  3OAB B;  4KK2 A;  1WKZ A;  2FTZ A;  4LPH F;  3UCA A;  3PYB A;  4EA2 A;  3PDE A;  4JZB A;  4LZ3 A;  2PS4 A;  3WCF A;  5IMI A;  3LGZ B;  5B0K A;  5ILK A;  3P41 A;  3KRF B;  4KPD A;  4DWB A;  4E9U A;  4LPG F;  2Z4Y A;  1YJ4 A;  1KIY A;  4DI5 A;  2Z7H A;  2Z4W A;  5HN9 A;  2E8T A;  5IK9 A;  1VG6 A;  1YHL A;  3VJC A;  1ZW5 A;  3V1X A;  2ZCR A;  1VG2 A;  3N3L F;  3LMD A;  5ILJ A;  4NG6 A;  5ERO A;  3N46 F;  3SDV A;  5IKA A;  3EFQ A;  4LLT A;  1YYS A;  4DWG A;  1HXG A;  3LSN A;  4LTV A;  4XQS F;  4XQR F;  3WSA A;  4DEM F;  2F94 F;  3OYR A;  5ILD A;  3OAC A;  2Q9Y A;  1V4I A;  5DW7 A;  1N22 A;  1V4H A;  2E8V A;  5IKH A;  4E9Z A;  1WL2 A;  5IK6 A;  2OPM A;  4FJQ A;  3G4F A;  4OKZ A;  3LK5 A;  2E8X A;  4NFJ F;  5ILZ A;  2J1P A;  4H5C F;  2ZY1 A;  4K10 A;  5DIQ F;  3WJK A;  4JYX A;  3NPR A;  3TFV A;  3WEI A;  4NFK F;  5EAU A;  4RNQ A;  2F89 F;  3RMG A;  1YQ7 A;  4XQT F;  2AEK A;  5HN7 A;  3WCG A;  2Z78 A;  1N1Z A;  1YHK A;  4JZX A;  4RXE A;  1YYQ A;  4RYP A;  3LOM A;  2OPN A;  4H5D F;  4LA6 A;  5B01 A;  2PS7 A;  2E8W A;  3Q2Q A;  4KKM A;  4KVI A;  3N0G A;  3P8R A;  1V4K A;  3WJO A;  3DYH A;  1HM7 A;  1RQJ A;  3W7F A;  3ZMB A;  2E4O A;  2F9K F;  5DGN F;  4LFE A;  3WCD A;  1VG4 A;  5IN8 A;  3MAV A;  1PS1 A;  2QIS A;  5IMN A;  3ZMC A;  5AHU B;  3QQV A;  4LZC A;  3M02 A;  2Z7I A;  3LVS A;  3WCE A;  1N24 A;  3N45 F;  3PH7 A;  1HX9 A;  4KQ5 A;  2P1C A;  3NRI A;  1DGP A;  3ADZ A;  4Q23 A;  2FOR A;  3LJI A;  3KRC A;  2AEL A;  3IPI A;  2ZCS A;  4FP4 A;  3LLW A;  3Q1O A;  4LLS A;  3WEG A;  3KRO A;  3Q2Z A;  3SDQ A;  3WJN A;  5JV1 F;  2PS6 A;  5E8L A;  3WCA A;  3N5H F;  3M0G A;  3N6K F;  4GP1 A;  5IVG A;  3ZL6 A;  2AZL A;  5KSX F;  3VJ9 A;  3QKC A;  3KRP A;  3OAB A;  3B7L A;  3AQ0 A;  5C05 A;  1JFG A;  5B0J A;  2E95 A;  4JVJ F;  3ACW A;  4RXA A;  3KRF A;  3N1W F;  3RYW A;  4LFG A;  2Q80 A;  1WL0 A;  3SAE A;  2E8U A;  3AQC B;  5ER8 A;  3WEH A;  3PKO A;  2O1O A;  2E91 A;  3MZV A;  3ACY A;  3N5J F;  3ZOU A;  5JUZ F;  4QPF A;  2Z4Z A;  3M01 A;  3WEK A;  3TFN A;  3BNY A;  3DYF A;  1N21 A;  2Z4V A;  3SDU A;  5B00 A;  3LGK A;  2OGD A;  4L2X F;  2I19 A;  1HM4 A;  2Z4X A;  5AYP A;  5E8H A;  5A0K A;  1KIZ A;  1HXA A;  3VJD A;  2E90 A;  4JXN A;  3V66 A;  3WE9 A;  3G4D A;  1DI1 A;  4N1Z F;  5ERM A;  2ZCQ A;  3WEF A;  4KVY A;  3P8L A;  5CG5 A;  1UBX A;  4H5E F;  3LG5 A;  4HD1 A;  4P0X A;  5ILY A;  3KRA B;  2AET A;  3WCH A;  4LIX A;  5AEL A;  4EA0 A;  5A0I A;  4NKE A;  3TC1 A;  2ONG A;  4UMJ A;  3VJA A;  2Q58 A;  5ILH A;  4KPJ A;  1N1B A;  4LZ0 A;  5EAS A;  1V4J A;  4F6V A;  4KVW A;  1YHM A;  3M9U A;  4LTZ A;  3NF2 A;  3IBA A;  4DHD A;  2Z50 A;  4P0V A;  5CG6 A;  3N1V F;  1UBV A;  2F8C F;  3ICN A;  3WSB A;  5DJV F;  3ASX A;  1WMW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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