3Q2ZA

Human squalene synthase in complex with n-[(3r,5s)-7-chloro-5-(2,3-dimethoxyphenyl)-1-neopentyl-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-acetyl]-l-aspartic acid
Total Genus 140
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
140
sequence length
333
structure length
333
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 140
structure length 333
sequence length 333
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2010-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3q2zA00
4LPHF 4QPFA 3WE9A 4NFIF 2E92A 3SDVA 3N5JF 2OGDA 5HN8A 2PS7A 3CC9A 3KRPA 3SAEA 3ICZA 3N1WF 5I1UA 1YQ7A 4KQSA 4KUXA 3AE0A 5B0LA 1VG4A 5CG6A 3M0GA 3N49F 2I19A 1ZW5A 1UBVA 5IM1A 4EA2A 5B02A 4P0VA 2ONHA 2ZCRA 3CKEA 2ZEUA 1RTRA 5IMIA 3N0GA 4PVYF 3P5PA 5ILHA 4LZ3A 3M02A 3PDEA 4WK5A 4RXAA 3S4JA 1N24A 3WEIA 4E9UA 2OPNA 4DXJA 2EWGA 5HN7A 1JFGA 3CP6A 3W7FA 1YYUA 3P8RA 2ZCOA 4DEMF 5ILJA 4LPGF 4MC0A 3APZA 4LIXA 4FJQA 1UBYA 3VJAA 3LVSA 4Q23A 3LK5A 3ZMBA 2E90A 3LJIA 4JZXA 5ER8A 3TS7A 4LZCA 3N46F 5ERNA 5EROA 5ILZA 3ASXA 4E9ZA 1YHMA 3LGZB 5CG5A 1HM4A 3AQCB 4KVYA 5DJRF 2Q9YA 1N1ZA 4L2XF 4LFVF 2PS6A 3BNYA 4MC3A 4RYPA 1YYSA 5AFXA 5B03A 4QXSF 4H5EF 3SDRA 3LLWA 3QQVA 3WCJA 1DGPA 3WEKA 3LGKA 1YYRA 5E8LA 3WSAA 2PS5A 5IKHA 3LZ9A 3NRIA 1YHKA 4DZWA 3RYEA 4LA5A 2Z4XA 3LEEA 3VJ8A 3OABA 4NKFA 3S9VA 3ADZA 1VG6A 4DWBA 5C05A 5EASA 4N1ZF 3WEHA 4JZBA 3M01A 3LDWA 4OKZA 5AELA 3LG5A 5ILKA 1HXCA 3EZ3A 3WJOA 2E94A 2E8VA 3VJEA 4N9UA 4HD1A 2Z52A 4OMHA 5DGSF 5IN8A 3KRAB 3IBAA 3LSNA 3N0FA 1WL1A 2J5CA 4UMJA 4NFJF 3N1VF 3WCIA 2AETA 4PVXF 1HM7A 4RNQA 3KRAA 2ONGA 3NPRA 2Q80A 3WJKA 3V66A 4H5DF 2PS4A 2E8XA 5ILIA 3WCGA 2ZCSA 3OACB 4JYXA 3RYWA 1HXAA 3TFVA 1HX9A 3OACA 2J1PA 2AELA 3TFPA 4JXNA 3AQ0A 3N5HF 2Q9ZA 2Z78A 4OMGA 5B00A 3WSBA 3ACXA 2F94F 4EA1A 5DHIA 2Z7HA 5IMPA 3KB9A 3TFNA 5IL3A 3KRFB 5JV0F 3MZVA 4LUUA 3KRFA 3M9UA 5E8KA 2FORA 1RQIA 5IMNA 3ID0A 5A0IA 2AZJA 5B0JA 4LTVA 3N3LF 3N6KF 3WCLA 1WMWA 4FP4A 3NF2A 4DWGA 2Z7IA 4LXWA 3WC9A 2E8TA 4DI5A 3EGTA 5JA0F 1N23A 3ZCDA 5JV2F 5AYPA 3WCMA 3WEFA 1V4KA 4LFGA 5E8HA 4LTZA 5IK0A 4LLSA 4RXDA 1UBXA 3OABB 2FTZA 2F92F 3V1XA 4OKMA 4KVWA 3WCCA 5DGMF 3EFQA 2AEKA 5IK6A 3N3DA 4XQTF 1FPSA 5KSXF 3BNXA 2E95A 3PYAA 4GP2A 3PKOA 4XQRF 5B0MA 3ACYA 3B7LA 3WCAA 3V1VA 4ZQ8A 2F89F 3Q30A 5EAUA 2Z4VA 4LA6A 5B01A 4KQUA 1JFAA 5ILYA 3KROA 1YHLA 5JV1F 4KK2A 2H8OA 4KWDA 3OYRA 5AHUB 1WKZA 4GAXA 4KPDA 4LZ0A 4LLTA 5DIQF 5A0KA 1YYTA 3UCAA 2E91A 2ZY1A 5A0JA 2O1OA 3VJDA 4NFKF 3SDQA 1DI1A 3G4FA 3DYHA 5JUZF 3RBMA 2AZKA 3ZOUA 3WEJA 2E8WA 1VG2A 1UBWA 2ZEVA 1N22A 4NKEA 3P5RA 3P41A 3AQBB 3ICMA 3ICNA 1N20A 4LOBA 1V4EA 3MAVA 2OA6A 5DW7A 4OGUA 3Q2ZA 3ZL6A 5EATA 1WL3A 4F62A 5IVGA 4EA0A 4KVIA 4KFAA 4XQSF 3PH7A 5B0IA 5H9DA 1WL0A 3LMDA 4KPJA 3QKCA 5HN9A 1YJ4A 4RXEA 1RQJA 3WCHA 3ICKA 2F9KF 2J1OA 3KBKA 2VF6A 1YYQA 3LOMA 1N21A 3VJBA 5HNAA 1KIYA 4GA3A 2F8ZF 2Z4ZA 4JXYA 1KIZA 1WL2A 5IKAA 3M00A 5DGNF 3IPIA 3SDTA 5B0KA 2P1CA 4GP1A 5IL8A 4LFEA 1HXGA 3DYFA 1VG3A 3N45F 4MC8A 3WJNA 2ZCQA 3SDUA 5DZ2A 1YV5A 1VG7A 4NG6A 2RAHA 3WCEA 3Q2QA 4KKMA 3VJ9A 5IK9A 2AZLA 2Q58A 4P0WA 5DHKA 5ILDA 5DJVF 3KRCB 2E8UA 3NPKA 3DYGA 4NUAA 3RMGA 4P0XA 1PS1A 3ACWA 4DHDA 4JVJF 1WY0A 2F8CF 3KRCA 3TC1A 2PS8A 2E93A 3KROB 3WCBA 1V4HA 2F7MF 3WEGA 4E1EA 4K10A 2Z50A 3VJCA 1V4IA 1N1BA 2DH4A 4F6XA 1V4JA 1EZFA 3PYBA 4KVDA 2OPMA 2Z4WA 4H5CF 4RXCA 2QISA 3G4DA 3WCFA 3Q1OA 3ZMCA 2Z4YA 3P8LA 4KQ5A 5DJPF 3KRPB 3WCDA 4F6VA 2E4OA 5ERMA
chains in the Genus database with same CATH superfamily
4LPHF 4QPFA 3WE9A 4NFIF 2E92A 3SDVA 3N5JF 2OGDA 5HN8A 2PS7A 3CC9A 3KRPA 3SAEA 3ICZA 3N1WF 5I1UA 1YQ7A 4KQSA 4KUXA 3AE0A 5B0LA 1VG4A 5CG6A 3M0GA 3N49F 2I19A 1ZW5A 1UBVA 5IM1A 4EA2A 5B02A 4P0VA 2ONHA 2ZCRA 3CKEA 2ZEUA 1RTRA 5IMIA 3N0GA 4PVYF 3P5PA 5ILHA 4LZ3A 3M02A 3PDEA 4WK5A 4RXAA 3S4JA 1N24A 3WEIA 4E9UA 2OPNA 4DXJA 2EWGA 5HN7A 1JFGA 3CP6A 3W7FA 1YYUA 3P8RA 2ZCOA 4DEMF 5ILJA 4LPGF 4MC0A 3APZA 4LIXA 4FJQA 1UBYA 3VJAA 3LVSA 4Q23A 3LK5A 3ZMBA 2E90A 3LJIA 4JZXA 5ER8A 3TS7A 4LZCA 3N46F 5ERNA 5EROA 5ILZA 3ASXA 4E9ZA 1YHMA 3LGZB 5CG5A 1HM4A 3AQCB 4KVYA 5DJRF 2Q9YA 1N1ZA 4L2XF 4LFVF 2PS6A 3BNYA 4MC3A 4RYPA 1YYSA 5AFXA 5B03A 4QXSF 4H5EF 3SDRA 3LLWA 3QQVA 3WCJA 1DGPA 3WEKA 3LGKA 1YYRA 5E8LA 3WSAA 2PS5A 5IKHA 3LZ9A 3NRIA 1YHKA 4DZWA 3RYEA 4LA5A 2Z4XA 3LEEA 3VJ8A 3OABA 4NKFA 3S9VA 3ADZA 1VG6A 4DWBA 5C05A 5EASA 4N1ZF 3WEHA 4JZBA 3M01A 3LDWA 4OKZA 5AELA 3LG5A 5ILKA 1HXCA 3EZ3A 3WJOA 2E94A 2E8VA 3VJEA 4N9UA 4HD1A 2Z52A 4OMHA 5DGSF 5IN8A 3KRAB 3IBAA 3LSNA 3N0FA 1WL1A 2J5CA 4UMJA 4NFJF 3N1VF 3WCIA 2AETA 4PVXF 1HM7A 4RNQA 3KRAA 2ONGA 3NPRA 2Q80A 3WJKA 3V66A 4H5DF 2PS4A 2E8XA 5ILIA 3WCGA 2ZCSA 3OACB 4JYXA 3RYWA 1HXAA 3TFVA 1HX9A 3OACA 2J1PA 2AELA 3TFPA 4JXNA 3AQ0A 3N5HF 2Q9ZA 2Z78A 4OMGA 5B00A 3WSBA 3ACXA 2F94F 4EA1A 5DHIA 2Z7HA 5IMPA 3KB9A 3TFNA 5IL3A 3KRFB 5JV0F 3MZVA 4LUUA 3KRFA 3M9UA 5E8KA 2FORA 1RQIA 5IMNA 3ID0A 5A0IA 2AZJA 5B0JA 4LTVA 3N3LF 3N6KF 3WCLA 1WMWA 4FP4A 3NF2A 4DWGA 2Z7IA 4LXWA 3WC9A 2E8TA 4DI5A 3EGTA 5JA0F 1N23A 3ZCDA 5JV2F 5AYPA 3WCMA 3WEFA 1V4KA 4LFGA 5E8HA 4LTZA 5IK0A 4LLSA 4RXDA 1UBXA 3OABB 2FTZA 2F92F 3V1XA 4OKMA 4KVWA 3WCCA 5DGMF 3EFQA 2AEKA 5IK6A 3N3DA 4XQTF 1FPSA 5KSXF 3BNXA 2E95A 3PYAA 4GP2A 3PKOA 4XQRF 5B0MA 3ACYA 3B7LA 3WCAA 3V1VA 4ZQ8A 2F89F 3Q30A 5EAUA 2Z4VA 4LA6A 5B01A 4KQUA 1JFAA 5ILYA 3KROA 1YHLA 5JV1F 4KK2A 2H8OA 4KWDA 3OYRA 5AHUB 1WKZA 4GAXA 4KPDA 4LZ0A 4LLTA 5DIQF 5A0KA 1YYTA 3UCAA 2E91A 2ZY1A 5A0JA 2O1OA 3VJDA 4NFKF 3SDQA 1DI1A 3G4FA 3DYHA 5JUZF 3RBMA 2AZKA 3ZOUA 3WEJA 2E8WA 1VG2A 1UBWA 2ZEVA 1N22A 4NKEA 3P5RA 3P41A 3AQBB 3ICMA 3ICNA 1N20A 4LOBA 1V4EA 3MAVA 2OA6A 5DW7A 4OGUA 3Q2ZA 3ZL6A 5EATA 1WL3A 4F62A 5IVGA 4EA0A 4KVIA 4KFAA 4XQSF 3PH7A 5B0IA 5H9DA 1WL0A 3LMDA 4KPJA 3QKCA 5HN9A 1YJ4A 4RXEA 1RQJA 3WCHA 3ICKA 2F9KF 2J1OA 3KBKA 2VF6A 1YYQA 3LOMA 1N21A 3VJBA 5HNAA 1KIYA 4GA3A 2F8ZF 2Z4ZA 4JXYA 1KIZA 1WL2A 5IKAA 3M00A 5DGNF 3IPIA 3SDTA 5B0KA 2P1CA 4GP1A 5IL8A 4LFEA 1HXGA 3DYFA 1VG3A 3N45F 4MC8A 3WJNA 2ZCQA 3SDUA 5DZ2A 1YV5A 1VG7A 4NG6A 2RAHA 3WCEA 3Q2QA 4KKMA 3VJ9A 5IK9A 2AZLA 2Q58A 4P0WA 5DHKA 5ILDA 5DJVF 3KRCB 2E8UA 3NPKA 3DYGA 4NUAA 3RMGA 4P0XA 1PS1A 3ACWA 4DHDA 4JVJF 1WY0A 2F8CF 3KRCA 3TC1A 2PS8A 2E93A 3KROB 3WCBA 1V4HA 2F7MF 3WEGA 4E1EA 4K10A 2Z50A 3VJCA 1V4IA 1N1BA 2DH4A 4F6XA 1V4JA 1EZFA 3PYBA 4KVDA 2OPMA 2Z4WA 4H5CF 4RXCA 2QISA 3G4DA 3WCFA 3Q1OA 3ZMCA 2Z4YA 3P8LA 4KQ5A 5DJPF 3KRPB 3WCDA 4F6VA 2E4OA 5ERMA
chains in the Genus database with same CATH topology
4LPHF 4QPFA 3WE9A 4NFIF 2E92A 3SDVA 3N5JF 2OGDA 5HN8A 2PS7A 3CC9A 3KRPA 3SAEA 3ICZA 3N1WF 5I1UA 1YQ7A 4KQSA 4KUXA 3AE0A 5B0LA 1VG4A 5CG6A 3M0GA 3N49F 2I19A 1ZW5A 1UBVA 5IM1A 4EA2A 5B02A 4P0VA 2ONHA 2ZCRA 3CKEA 2ZEUA 1RTRA 5IMIA 3N0GA 4PVYF 3P5PA 5ILHA 4LZ3A 3M02A 3PDEA 4WK5A 4RXAA 3S4JA 1N24A 3WEIA 4E9UA 2OPNA 4DXJA 2EWGA 5HN7A 1JFGA 3CP6A 3W7FA 1YYUA 3P8RA 2ZCOA 4DEMF 5ILJA 4LPGF 4MC0A 3APZA 4LIXA 4FJQA 1UBYA 3VJAA 3LVSA 4Q23A 3LK5A 3ZMBA 2E90A 3LJIA 4JZXA 5ER8A 3TS7A 4LZCA 3N46F 5ERNA 5EROA 5ILZA 3ASXA 4E9ZA 1YHMA 3LGZB 5CG5A 1HM4A 3AQCB 4KVYA 5DJRF 2Q9YA 1N1ZA 4L2XF 4LFVF 2PS6A 3BNYA 4MC3A 4RYPA 1YYSA 5AFXA 5B03A 4QXSF 4H5EF 3SDRA 3LLWA 3QQVA 3WCJA 1DGPA 3WEKA 3LGKA 1YYRA 5E8LA 3WSAA 2PS5A 5IKHA 3LZ9A 3NRIA 1YHKA 4DZWA 3RYEA 4LA5A 2Z4XA 3LEEA 3VJ8A 3OABA 4NKFA 3S9VA 3ADZA 1VG6A 4DWBA 5C05A 5EASA 4N1ZF 3WEHA 4JZBA 3M01A 3LDWA 4OKZA 5AELA 3LG5A 5ILKA 1HXCA 3EZ3A 3WJOA 2E94A 2E8VA 3VJEA 4N9UA 4HD1A 2Z52A 4OMHA 5DGSF 5IN8A 3KRAB 3IBAA 3LSNA 3N0FA 1WL1A 2J5CA 4UMJA 4NFJF 3N1VF 3WCIA 2AETA 4PVXF 1HM7A 4RNQA 3KRAA 2ONGA 3NPRA 2Q80A 3WJKA 3V66A 4H5DF 2PS4A 2E8XA 5ILIA 3WCGA 2ZCSA 3OACB 4JYXA 3RYWA 1HXAA 3TFVA 1HX9A 3OACA 2J1PA 2AELA 3TFPA 4JXNA 3AQ0A 3N5HF 2Q9ZA 2Z78A 4OMGA 5B00A 3WSBA 3ACXA 2F94F 4EA1A 5DHIA 2Z7HA 5IMPA 3KB9A 3TFNA 5IL3A 3KRFB 5JV0F 3MZVA 4LUUA 3KRFA 3M9UA 5E8KA 2FORA 1RQIA 5IMNA 3ID0A 5A0IA 2AZJA 5B0JA 4LTVA 3N3LF 3N6KF 3WCLA 1WMWA 4FP4A 3NF2A 4DWGA 2Z7IA 4LXWA 3WC9A 2E8TA 4DI5A 3EGTA 5JA0F 1N23A 3ZCDA 5JV2F 5AYPA 3WCMA 3WEFA 1V4KA 4LFGA 5E8HA 4LTZA 5IK0A 4LLSA 4RXDA 1UBXA 3OABB 2FTZA 2F92F 3V1XA 4OKMA 4KVWA 3WCCA 5DGMF 3EFQA 2AEKA 5IK6A 3N3DA 4XQTF 1FPSA 5KSXF 3BNXA 2E95A 3PYAA 4GP2A 3PKOA 4XQRF 5B0MA 3ACYA 3B7LA 3WCAA 3V1VA 4ZQ8A 2F89F 3Q30A 5EAUA 2Z4VA 4LA6A 5B01A 4KQUA 1JFAA 5ILYA 3KROA 1YHLA 5JV1F 4KK2A 2H8OA 4KWDA 3OYRA 5AHUB 1WKZA 4GAXA 4KPDA 4LZ0A 4LLTA 5DIQF 5A0KA 1YYTA 3UCAA 2E91A 2ZY1A 5A0JA 2O1OA 3VJDA 4NFKF 3SDQA 1DI1A 3G4FA 3DYHA 5JUZF 3RBMA 2AZKA 3ZOUA 3WEJA 2E8WA 1VG2A 1UBWA 2ZEVA 1N22A 4NKEA 3P5RA 3P41A 3AQBB 3ICMA 3ICNA 1N20A 4LOBA 1V4EA 3MAVA 2OA6A 5DW7A 4OGUA 3Q2ZA 3ZL6A 5EATA 1WL3A 4F62A 5IVGA 4EA0A 4KVIA 4KFAA 4XQSF 3PH7A 5B0IA 5H9DA 1WL0A 3LMDA 4KPJA 3QKCA 5HN9A 1YJ4A 4RXEA 1RQJA 3WCHA 3ICKA 2F9KF 2J1OA 3KBKA 2VF6A 1YYQA 3LOMA 1N21A 3VJBA 5HNAA 1KIYA 4GA3A 2F8ZF 2Z4ZA 4JXYA 1KIZA 1WL2A 5IKAA 3M00A 5DGNF 3IPIA 3SDTA 5B0KA 2P1CA 4GP1A 5IL8A 4LFEA 1HXGA 3DYFA 1VG3A 3N45F 4MC8A 3WJNA 2ZCQA 3SDUA 5DZ2A 1YV5A 1VG7A 4NG6A 2RAHA 3WCEA 3Q2QA 4KKMA 3VJ9A 5IK9A 2AZLA 2Q58A 4P0WA 5DHKA 5ILDA 5DJVF 3KRCB 2E8UA 3NPKA 3DYGA 4NUAA 3RMGA 4P0XA 1PS1A 3ACWA 4DHDA 4JVJF 1WY0A 2F8CF 3KRCA 3TC1A 2PS8A 2E93A 3KROB 3WCBA 1V4HA 2F7MF 3WEGA 4E1EA 4K10A 2Z50A 3VJCA 1V4IA 1N1BA 2DH4A 4F6XA 1V4JA 1EZFA 3PYBA 4KVDA 2OPMA 2Z4WA 4H5CF 4RXCA 2QISA 3G4DA 3WCFA 3Q1OA 3ZMCA 2Z4YA 3P8LA 4KQ5A 5DJPF 3KRPB 3WCDA 4F6VA 2E4OA 5ERMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LPH F;  4QPF A;  3WE9 A;  4NFI F;  2E92 A;  3SDV A;  3N5J F;  2OGD A;  5HN8 A;  2PS7 A;  3CC9 A;  3KRP A;  3SAE A;  3ICZ A;  3N1W F;  5I1U A;  1YQ7 A;  4KQS A;  4KUX A;  3AE0 A;  5B0L A;  1VG4 A;  5CG6 A;  3M0G A;  3N49 F;  2I19 A;  1ZW5 A;  1UBV A;  5IM1 A;  4EA2 A;  5B02 A;  4P0V A;  2ONH A;  2ZCR A;  3CKE A;  2ZEU A;  1RTR A;  5IMI A;  3N0G A;  4PVY F;  3P5P A;  5ILH A;  4LZ3 A;  3M02 A;  3PDE A;  4WK5 A;  4RXA A;  3S4J A;  1N24 A;  3WEI A;  4E9U A;  2OPN A;  4DXJ A;  2EWG A;  5HN7 A;  1JFG A;  3CP6 A;  3W7F A;  1YYU A;  3P8R A;  2ZCO A;  4DEM F;  5ILJ A;  4LPG F;  4MC0 A;  3APZ A;  4LIX A;  4FJQ A;  1UBY A;  3VJA A;  3LVS A;  4Q23 A;  3LK5 A;  3ZMB A;  2E90 A;  3LJI A;  4JZX A;  5ER8 A;  3TS7 A;  4LZC A;  3N46 F;  5ERN A;  5ERO A;  5ILZ A;  3ASX A;  4E9Z A;  1YHM A;  3LGZ B;  5CG5 A;  1HM4 A;  3AQC B;  4KVY A;  5DJR F;  2Q9Y A;  1N1Z A;  4L2X F;  4LFV F;  2PS6 A;  3BNY A;  4MC3 A;  4RYP A;  1YYS A;  5AFX A;  5B03 A;  4QXS F;  4H5E F;  3SDR A;  3LLW A;  3QQV A;  3WCJ A;  1DGP A;  3WEK A;  3LGK A;  1YYR A;  5E8L A;  3WSA A;  2PS5 A;  5IKH A;  3LZ9 A;  3NRI A;  1YHK A;  4DZW A;  3RYE A;  4LA5 A;  2Z4X A;  3LEE A;  3VJ8 A;  3OAB A;  4NKF A;  3S9V A;  3ADZ A;  1VG6 A;  4DWB A;  5C05 A;  5EAS A;  4N1Z F;  3WEH A;  4JZB A;  3M01 A;  3LDW A;  4OKZ A;  5AEL A;  3LG5 A;  5ILK A;  1HXC A;  3EZ3 A;  3WJO A;  2E94 A;  2E8V A;  3VJE A;  4N9U A;  4HD1 A;  2Z52 A;  4OMH A;  5DGS F;  5IN8 A;  3KRA B;  3IBA A;  3LSN A;  3N0F A;  1WL1 A;  2J5C A;  4UMJ A;  4NFJ F;  3N1V F;  3WCI A;  2AET A;  4PVX F;  1HM7 A;  4RNQ A;  3KRA A;  2ONG A;  3NPR A;  2Q80 A;  3WJK A;  3V66 A;  4H5D F;  2PS4 A;  2E8X A;  5ILI A;  3WCG A;  2ZCS A;  3OAC B;  4JYX A;  3RYW A;  1HXA A;  3TFV A;  1HX9 A;  3OAC A;  2J1P A;  2AEL A;  3TFP A;  4JXN A;  3AQ0 A;  3N5H F;  2Q9Z A;  2Z78 A;  4OMG A;  5B00 A;  3WSB A;  3ACX A;  2F94 F;  4EA1 A;  5DHI A;  2Z7H A;  5IMP A;  3KB9 A;  3TFN A;  5IL3 A;  3KRF B;  5JV0 F;  3MZV A;  4LUU A;  3KRF A;  3M9U A;  5E8K A;  2FOR A;  1RQI A;  5IMN A;  3ID0 A;  5A0I A;  2AZJ A;  5B0J A;  4LTV A;  3N3L F;  3N6K F;  3WCL A;  1WMW A;  4FP4 A;  3NF2 A;  4DWG A;  2Z7I A;  4LXW A;  3WC9 A;  2E8T A;  4DI5 A;  3EGT A;  5JA0 F;  1N23 A;  3ZCD A;  5JV2 F;  5AYP A;  3WCM A;  3WEF A;  1V4K A;  4LFG A;  5E8H A;  4LTZ A;  5IK0 A;  4LLS A;  4RXD A;  1UBX A;  3OAB B;  2FTZ A;  2F92 F;  3V1X A;  4OKM A;  4KVW A;  3WCC A;  5DGM F;  3EFQ A;  2AEK A;  5IK6 A;  3N3D A;  4XQT F;  1FPS A;  5KSX F;  3BNX A;  2E95 A;  3PYA A;  4GP2 A;  3PKO A;  4XQR F;  5B0M A;  3ACY A;  3B7L A;  3WCA A;  3V1V A;  4ZQ8 A;  2F89 F;  3Q30 A;  5EAU A;  2Z4V A;  4LA6 A;  5B01 A;  4KQU A;  1JFA A;  5ILY A;  3KRO A;  1YHL A;  5JV1 F;  4KK2 A;  2H8O A;  4KWD A;  3OYR A;  5AHU B;  1WKZ A;  4GAX A;  4KPD A;  4LZ0 A;  4LLT A;  5DIQ F;  5A0K A;  1YYT A;  3UCA A;  2E91 A;  2ZY1 A;  5A0J A;  2O1O A;  3VJD A;  4NFK F;  3SDQ A;  1DI1 A;  3G4F A;  3DYH A;  5JUZ F;  3RBM A;  2AZK A;  3ZOU A;  3WEJ A;  2E8W A;  1VG2 A;  1UBW A;  2ZEV A;  1N22 A;  4NKE A;  3P5R A;  3P41 A;  3AQB B;  3ICM A;  3ICN A;  1N20 A;  4LOB A;  1V4E A;  3MAV A;  2OA6 A;  5DW7 A;  4OGU A;  3Q2Z A;  3ZL6 A;  5EAT A;  1WL3 A;  4F62 A;  5IVG A;  4EA0 A;  4KVI A;  4KFA A;  4XQS F;  3PH7 A;  5B0I A;  5H9D A;  1WL0 A;  3LMD A;  4KPJ A;  3QKC A;  5HN9 A;  1YJ4 A;  4RXE A;  1RQJ A;  3WCH A;  3ICK A;  2F9K F;  2J1O A;  3KBK A;  2VF6 A;  1YYQ A;  3LOM A;  1N21 A;  3VJB A;  5HNA A;  1KIY A;  4GA3 A;  2F8Z F;  2Z4Z A;  4JXY A;  1KIZ A;  1WL2 A;  5IKA A;  3M00 A;  5DGN F;  3IPI A;  3SDT A;  5B0K A;  2P1C A;  4GP1 A;  5IL8 A;  4LFE A;  1HXG A;  3DYF A;  1VG3 A;  3N45 F;  4MC8 A;  3WJN A;  2ZCQ A;  3SDU A;  5DZ2 A;  1YV5 A;  1VG7 A;  4NG6 A;  2RAH A;  3WCE A;  3Q2Q A;  4KKM A;  3VJ9 A;  5IK9 A;  2AZL A;  2Q58 A;  4P0W A;  5DHK A;  5ILD A;  5DJV F;  3KRC B;  2E8U A;  3NPK A;  3DYG A;  4NUA A;  3RMG A;  4P0X A;  1PS1 A;  3ACW A;  4DHD A;  4JVJ F;  1WY0 A;  2F8C F;  3KRC A;  3TC1 A;  2PS8 A;  2E93 A;  3KRO B;  3WCB A;  1V4H A;  2F7M F;  3WEG A;  4E1E A;  4K10 A;  2Z50 A;  3VJC A;  1V4I A;  1N1B A;  2DH4 A;  4F6X A;  1V4J A;  1EZF A;  3PYB A;  4KVD A;  2OPM A;  2Z4W A;  4H5C F;  4RXC A;  2QIS A;  3G4D A;  3WCF A;  3Q1O A;  3ZMC A;  2Z4Y A;  3P8L A;  4KQ5 A;  5DJP F;  3KRP B;  3WCD A;  4F6V A;  2E4O A;  5ERM A; 
#chains in the Genus database with same CATH topology
 4LPH F;  4QPF A;  3WE9 A;  4NFI F;  2E92 A;  3SDV A;  3N5J F;  2OGD A;  5HN8 A;  2PS7 A;  3CC9 A;  3KRP A;  3SAE A;  3ICZ A;  3N1W F;  5I1U A;  1YQ7 A;  4KQS A;  4KUX A;  3AE0 A;  5B0L A;  1VG4 A;  5CG6 A;  3M0G A;  3N49 F;  2I19 A;  1ZW5 A;  1UBV A;  5IM1 A;  4EA2 A;  5B02 A;  4P0V A;  2ONH A;  2ZCR A;  3CKE A;  2ZEU A;  1RTR A;  5IMI A;  3N0G A;  4PVY F;  3P5P A;  5ILH A;  4LZ3 A;  3M02 A;  3PDE A;  4WK5 A;  4RXA A;  3S4J A;  1N24 A;  3WEI A;  4E9U A;  2OPN A;  4DXJ A;  2EWG A;  5HN7 A;  1JFG A;  3CP6 A;  3W7F A;  1YYU A;  3P8R A;  2ZCO A;  4DEM F;  5ILJ A;  4LPG F;  4MC0 A;  3APZ A;  4LIX A;  4FJQ A;  1UBY A;  3VJA A;  3LVS A;  4Q23 A;  3LK5 A;  3ZMB A;  2E90 A;  3LJI A;  4JZX A;  5ER8 A;  3TS7 A;  4LZC A;  3N46 F;  5ERN A;  5ERO A;  5ILZ A;  3ASX A;  4E9Z A;  1YHM A;  3LGZ B;  5CG5 A;  1HM4 A;  3AQC B;  4KVY A;  5DJR F;  2Q9Y A;  1N1Z A;  4L2X F;  4LFV F;  2PS6 A;  3BNY A;  4MC3 A;  4RYP A;  1YYS A;  5AFX A;  5B03 A;  4QXS F;  4H5E F;  3SDR A;  3LLW A;  3QQV A;  3WCJ A;  1DGP A;  3WEK A;  3LGK A;  1YYR A;  5E8L A;  3WSA A;  2PS5 A;  5IKH A;  3LZ9 A;  3NRI A;  1YHK A;  4DZW A;  3RYE A;  4LA5 A;  2Z4X A;  3LEE A;  3VJ8 A;  3OAB A;  4NKF A;  3S9V A;  3ADZ A;  1VG6 A;  4DWB A;  5C05 A;  5EAS A;  4N1Z F;  3WEH A;  4JZB A;  3M01 A;  3LDW A;  4OKZ A;  5AEL A;  3LG5 A;  5ILK A;  1HXC A;  3EZ3 A;  3WJO A;  2E94 A;  2E8V A;  3VJE A;  4N9U A;  4HD1 A;  2Z52 A;  4OMH A;  5DGS F;  5IN8 A;  3KRA B;  3IBA A;  3LSN A;  3N0F A;  1WL1 A;  2J5C A;  4UMJ A;  4NFJ F;  3N1V F;  3WCI A;  2AET A;  4PVX F;  1HM7 A;  4RNQ A;  3KRA A;  2ONG A;  3NPR A;  2Q80 A;  3WJK A;  3V66 A;  4H5D F;  2PS4 A;  2E8X A;  5ILI A;  3WCG A;  2ZCS A;  3OAC B;  4JYX A;  3RYW A;  1HXA A;  3TFV A;  1HX9 A;  3OAC A;  2J1P A;  2AEL A;  3TFP A;  4JXN A;  3AQ0 A;  3N5H F;  2Q9Z A;  2Z78 A;  4OMG A;  5B00 A;  3WSB A;  3ACX A;  2F94 F;  4EA1 A;  5DHI A;  2Z7H A;  5IMP A;  3KB9 A;  3TFN A;  5IL3 A;  3KRF B;  5JV0 F;  3MZV A;  4LUU A;  3KRF A;  3M9U A;  5E8K A;  2FOR A;  1RQI A;  5IMN A;  3ID0 A;  5A0I A;  2AZJ A;  5B0J A;  4LTV A;  3N3L F;  3N6K F;  3WCL A;  1WMW A;  4FP4 A;  3NF2 A;  4DWG A;  2Z7I A;  4LXW A;  3WC9 A;  2E8T A;  4DI5 A;  3EGT A;  5JA0 F;  1N23 A;  3ZCD A;  5JV2 F;  5AYP A;  3WCM A;  3WEF A;  1V4K A;  4LFG A;  5E8H A;  4LTZ A;  5IK0 A;  4LLS A;  4RXD A;  1UBX A;  3OAB B;  2FTZ A;  2F92 F;  3V1X A;  4OKM A;  4KVW A;  3WCC A;  5DGM F;  3EFQ A;  2AEK A;  5IK6 A;  3N3D A;  4XQT F;  1FPS A;  5KSX F;  3BNX A;  2E95 A;  3PYA A;  4GP2 A;  3PKO A;  4XQR F;  5B0M A;  3ACY A;  3B7L A;  3WCA A;  3V1V A;  4ZQ8 A;  2F89 F;  3Q30 A;  5EAU A;  2Z4V A;  4LA6 A;  5B01 A;  4KQU A;  1JFA A;  5ILY A;  3KRO A;  1YHL A;  5JV1 F;  4KK2 A;  2H8O A;  4KWD A;  3OYR A;  5AHU B;  1WKZ A;  4GAX A;  4KPD A;  4LZ0 A;  4LLT A;  5DIQ F;  5A0K A;  1YYT A;  3UCA A;  2E91 A;  2ZY1 A;  5A0J A;  2O1O A;  3VJD A;  4NFK F;  3SDQ A;  1DI1 A;  3G4F A;  3DYH A;  5JUZ F;  3RBM A;  2AZK A;  3ZOU A;  3WEJ A;  2E8W A;  1VG2 A;  1UBW A;  2ZEV A;  1N22 A;  4NKE A;  3P5R A;  3P41 A;  3AQB B;  3ICM A;  3ICN A;  1N20 A;  4LOB A;  1V4E A;  3MAV A;  2OA6 A;  5DW7 A;  4OGU A;  3Q2Z A;  3ZL6 A;  5EAT A;  1WL3 A;  4F62 A;  5IVG A;  4EA0 A;  4KVI A;  4KFA A;  4XQS F;  3PH7 A;  5B0I A;  5H9D A;  1WL0 A;  3LMD A;  4KPJ A;  3QKC A;  5HN9 A;  1YJ4 A;  4RXE A;  1RQJ A;  3WCH A;  3ICK A;  2F9K F;  2J1O A;  3KBK A;  2VF6 A;  1YYQ A;  3LOM A;  1N21 A;  3VJB A;  5HNA A;  1KIY A;  4GA3 A;  2F8Z F;  2Z4Z A;  4JXY A;  1KIZ A;  1WL2 A;  5IKA A;  3M00 A;  5DGN F;  3IPI A;  3SDT A;  5B0K A;  2P1C A;  4GP1 A;  5IL8 A;  4LFE A;  1HXG A;  3DYF A;  1VG3 A;  3N45 F;  4MC8 A;  3WJN A;  2ZCQ A;  3SDU A;  5DZ2 A;  1YV5 A;  1VG7 A;  4NG6 A;  2RAH A;  3WCE A;  3Q2Q A;  4KKM A;  3VJ9 A;  5IK9 A;  2AZL A;  2Q58 A;  4P0W A;  5DHK A;  5ILD A;  5DJV F;  3KRC B;  2E8U A;  3NPK A;  3DYG A;  4NUA A;  3RMG A;  4P0X A;  1PS1 A;  3ACW A;  4DHD A;  4JVJ F;  1WY0 A;  2F8C F;  3KRC A;  3TC1 A;  2PS8 A;  2E93 A;  3KRO B;  3WCB A;  1V4H A;  2F7M F;  3WEG A;  4E1E A;  4K10 A;  2Z50 A;  3VJC A;  1V4I A;  1N1B A;  2DH4 A;  4F6X A;  1V4J A;  1EZF A;  3PYB A;  4KVD A;  2OPM A;  2Z4W A;  4H5C F;  4RXC A;  2QIS A;  3G4D A;  3WCF A;  3Q1O A;  3ZMC A;  2Z4Y A;  3P8L A;  4KQ5 A;  5DJP F;  3KRP B;  3WCD A;  4F6V A;  2E4O A;  5ERM A; 
#chains in the Genus database with same CATH homology
 4LPH F;  4QPF A;  3WE9 A;  4NFI F;  2E92 A;  3SDV A;  3N5J F;  2OGD A;  5HN8 A;  2PS7 A;  3CC9 A;  3KRP A;  3SAE A;  3ICZ A;  3N1W F;  5I1U A;  1YQ7 A;  4KQS A;  4KUX A;  3AE0 A;  5B0L A;  1VG4 A;  5CG6 A;  3M0G A;  3N49 F;  2I19 A;  1ZW5 A;  1UBV A;  5IM1 A;  4EA2 A;  5B02 A;  4P0V A;  2ONH A;  2ZCR A;  3CKE A;  2ZEU A;  1RTR A;  5IMI A;  3N0G A;  4PVY F;  3P5P A;  5ILH A;  4LZ3 A;  3M02 A;  3PDE A;  4WK5 A;  4RXA A;  3S4J A;  1N24 A;  3WEI A;  4E9U A;  2OPN A;  4DXJ A;  2EWG A;  5HN7 A;  1JFG A;  3CP6 A;  3W7F A;  1YYU A;  3P8R A;  2ZCO A;  4DEM F;  5ILJ A;  4LPG F;  4MC0 A;  3APZ A;  4LIX A;  4FJQ A;  1UBY A;  3VJA A;  3LVS A;  4Q23 A;  3LK5 A;  3ZMB A;  2E90 A;  3LJI A;  4JZX A;  5ER8 A;  3TS7 A;  4LZC A;  3N46 F;  5ERN A;  5ERO A;  5ILZ A;  3ASX A;  4E9Z A;  1YHM A;  3LGZ B;  5CG5 A;  1HM4 A;  3AQC B;  4KVY A;  5DJR F;  2Q9Y A;  1N1Z A;  4L2X F;  4LFV F;  2PS6 A;  3BNY A;  4MC3 A;  4RYP A;  1YYS A;  5AFX A;  5B03 A;  4QXS F;  4H5E F;  3SDR A;  3LLW A;  3QQV A;  3WCJ A;  1DGP A;  3WEK A;  3LGK A;  1YYR A;  5E8L A;  3WSA A;  2PS5 A;  5IKH A;  3LZ9 A;  3NRI A;  1YHK A;  4DZW A;  3RYE A;  4LA5 A;  2Z4X A;  3LEE A;  3VJ8 A;  3OAB A;  4NKF A;  3S9V A;  3ADZ A;  1VG6 A;  4DWB A;  5C05 A;  5EAS A;  4N1Z F;  3WEH A;  4JZB A;  3M01 A;  3LDW A;  4OKZ A;  5AEL A;  3LG5 A;  5ILK A;  1HXC A;  3EZ3 A;  3WJO A;  2E94 A;  2E8V A;  3VJE A;  4N9U A;  4HD1 A;  2Z52 A;  4OMH A;  5DGS F;  5IN8 A;  3KRA B;  3IBA A;  3LSN A;  3N0F A;  1WL1 A;  2J5C A;  4UMJ A;  4NFJ F;  3N1V F;  3WCI A;  2AET A;  4PVX F;  1HM7 A;  4RNQ A;  3KRA A;  2ONG A;  3NPR A;  2Q80 A;  3WJK A;  3V66 A;  4H5D F;  2PS4 A;  2E8X A;  5ILI A;  3WCG A;  2ZCS A;  3OAC B;  4JYX A;  3RYW A;  1HXA A;  3TFV A;  1HX9 A;  3OAC A;  2J1P A;  2AEL A;  3TFP A;  4JXN A;  3AQ0 A;  3N5H F;  2Q9Z A;  2Z78 A;  4OMG A;  5B00 A;  3WSB A;  3ACX A;  2F94 F;  4EA1 A;  5DHI A;  2Z7H A;  5IMP A;  3KB9 A;  3TFN A;  5IL3 A;  3KRF B;  5JV0 F;  3MZV A;  4LUU A;  3KRF A;  3M9U A;  5E8K A;  2FOR A;  1RQI A;  5IMN A;  3ID0 A;  5A0I A;  2AZJ A;  5B0J A;  4LTV A;  3N3L F;  3N6K F;  3WCL A;  1WMW A;  4FP4 A;  3NF2 A;  4DWG A;  2Z7I A;  4LXW A;  3WC9 A;  2E8T A;  4DI5 A;  3EGT A;  5JA0 F;  1N23 A;  3ZCD A;  5JV2 F;  5AYP A;  3WCM A;  3WEF A;  1V4K A;  4LFG A;  5E8H A;  4LTZ A;  5IK0 A;  4LLS A;  4RXD A;  1UBX A;  3OAB B;  2FTZ A;  2F92 F;  3V1X A;  4OKM A;  4KVW A;  3WCC A;  5DGM F;  3EFQ A;  2AEK A;  5IK6 A;  3N3D A;  4XQT F;  1FPS A;  5KSX F;  3BNX A;  2E95 A;  3PYA A;  4GP2 A;  3PKO A;  4XQR F;  5B0M A;  3ACY A;  3B7L A;  3WCA A;  3V1V A;  4ZQ8 A;  2F89 F;  3Q30 A;  5EAU A;  2Z4V A;  4LA6 A;  5B01 A;  4KQU A;  1JFA A;  5ILY A;  3KRO A;  1YHL A;  5JV1 F;  4KK2 A;  2H8O A;  4KWD A;  3OYR A;  5AHU B;  1WKZ A;  4GAX A;  4KPD A;  4LZ0 A;  4LLT A;  5DIQ F;  5A0K A;  1YYT A;  3UCA A;  2E91 A;  2ZY1 A;  5A0J A;  2O1O A;  3VJD A;  4NFK F;  3SDQ A;  1DI1 A;  3G4F A;  3DYH A;  5JUZ F;  3RBM A;  2AZK A;  3ZOU A;  3WEJ A;  2E8W A;  1VG2 A;  1UBW A;  2ZEV A;  1N22 A;  4NKE A;  3P5R A;  3P41 A;  3AQB B;  3ICM A;  3ICN A;  1N20 A;  4LOB A;  1V4E A;  3MAV A;  2OA6 A;  5DW7 A;  4OGU A;  3Q2Z A;  3ZL6 A;  5EAT A;  1WL3 A;  4F62 A;  5IVG A;  4EA0 A;  4KVI A;  4KFA A;  4XQS F;  3PH7 A;  5B0I A;  5H9D A;  1WL0 A;  3LMD A;  4KPJ A;  3QKC A;  5HN9 A;  1YJ4 A;  4RXE A;  1RQJ A;  3WCH A;  3ICK A;  2F9K F;  2J1O A;  3KBK A;  2VF6 A;  1YYQ A;  3LOM A;  1N21 A;  3VJB A;  5HNA A;  1KIY A;  4GA3 A;  2F8Z F;  2Z4Z A;  4JXY A;  1KIZ A;  1WL2 A;  5IKA A;  3M00 A;  5DGN F;  3IPI A;  3SDT A;  5B0K A;  2P1C A;  4GP1 A;  5IL8 A;  4LFE A;  1HXG A;  3DYF A;  1VG3 A;  3N45 F;  4MC8 A;  3WJN A;  2ZCQ A;  3SDU A;  5DZ2 A;  1YV5 A;  1VG7 A;  4NG6 A;  2RAH A;  3WCE A;  3Q2Q A;  4KKM A;  3VJ9 A;  5IK9 A;  2AZL A;  2Q58 A;  4P0W A;  5DHK A;  5ILD A;  5DJV F;  3KRC B;  2E8U A;  3NPK A;  3DYG A;  4NUA A;  3RMG A;  4P0X A;  1PS1 A;  3ACW A;  4DHD A;  4JVJ F;  1WY0 A;  2F8C F;  3KRC A;  3TC1 A;  2PS8 A;  2E93 A;  3KRO B;  3WCB A;  1V4H A;  2F7M F;  3WEG A;  4E1E A;  4K10 A;  2Z50 A;  3VJC A;  1V4I A;  1N1B A;  2DH4 A;  4F6X A;  1V4J A;  1EZF A;  3PYB A;  4KVD A;  2OPM A;  2Z4W A;  4H5C F;  4RXC A;  2QIS A;  3G4D A;  3WCF A;  3Q1O A;  3ZMC A;  2Z4Y A;  3P8L A;  4KQ5 A;  5DJP F;  3KRP B;  3WCD A;  4F6V A;  2E4O A;  5ERM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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