The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
175
|
sequence length |
720
|
structure length |
674
|
Chain Sequence |
SSQGLLGYYFSDLNFQAPMVVTSSTTGDLSIPSSELPSENQYFQSAIWSGFIKVSDEYTFATSADNHVTMWVDDQEVINNKIRLEKGRLYQIKIQYQRENPTEKGLDFKLYWTDSQNKKEVISSDNLQLPELKQKSSNSRKKRPDRDNDGIPDSLEVEGYTVDVKNKRTFLSPWISNIHEKKGLTKYKSSPEKWSTASDPYSDFEKVTGRIDKNVSPEARHPLVAAYPIVHVDMENIILSKNEDSQTRTISKNTSTSRTHTSAGFSNSNSSTVAIDHSLSAGERTWAETMGLNTADTARLNANIRYVNTGTAPIYNVLPTTSLVLGKNQTLATIKAKENQLSQILAPNNYYPSKNLAPIALNAQDDFSSTPITMNYNQFLELEKTKQLRLDTDQVYGNIATYNFENGRVRVDTGSNWSEVLPQIQETTARIIFNGKDLNLVERRIAAVNPSDPLETTKPDMTLKEALKIAFGFNEPNGNLQYQGKDITEFDFNFDQQTSQNIKNQLAELNATNIYTVLDKIKLNAKMNILIRDKRFHYDRNNIAVGADESVVKEAHREVINSSTEGLLLNIDKDIRKILSGYIVEIEDTEGLKEVINDRYDMLNISSLRQDGKTFIDFKKYNDKLPLYISNPNYKVNVYAVTKENTIINPSENGDTSTNGIKKILIFSKKGYEI
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2.
pubmed doi rcsb |
| molecule tags |
Toxin
|
| source organism |
Bacillus anthracis
|
| molecule keywords |
Protective antigen
|
| total genus |
175
|
| structure length |
674
|
| sequence length |
720
|
| ec nomenclature | |
| pdb deposition date | 2011-01-06 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF03495 | Binary_toxB | Clostridial binary toxin B/anthrax toxin PA Ca-binding domain |
| A | PF07691 | PA14 | PA14 domain |
| A | PF17475 | Binary_toxB_2 | Clostridial binary toxin B/anthrax toxin PA domain 2 |
| A | PF17476 | Binary_toxB_3 | Clostridial binary toxin B/anthrax toxin PA domain 3 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulin-like | ||
| Mainly Beta | Sandwich | Jelly Rolls | Protective antigen, heptamerisation domain | ||
| Alpha Beta | Roll | Ubiquitin-like (UB roll) | Ubiquitin-like (UB roll) | ||
| Alpha Beta | Alpha-Beta Complex | Toxin - Anthrax Protective Antigen; domain 1 | Toxin - Anthrax Protective Antigen;domain 1 |
