3QCKA

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]benzoic acid
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
302
structure length
289
Chain Sequence
MEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPLPSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
pubmed doi rcsb
molecule keywords Receptor-type tyrosine-protein phosphatase gamma
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 96
structure length 289
sequence length 302
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2011-01-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3qckA00
3MOZA 2PSZA 1ZC0A 2FJMA 4GE2A 1OETA 2HVLA 1Q6PA 1VHRA 2HC1A 3QCLA 3ZMPA 5K9VA 3S3HA 1NL9A 2OOQA 1ZCKA 4IKCA 1LQFA 1G7FA 5IBSA 4DGPA 5KA9A 3S3FA 5KAAA 2CNHA 2OC3A 2Q47A 2HNQA 3QCHA 3BRHA 1D5RA 1PTTA 4RDDA 3D9CA 3S3EA 4I8NA 1YWFA 2F6FA 3V0EA 1YTWA 2VEUA 4KYRA 4RH5A 1U26A 2JJDA 2QBRA 1RPMA 1OEUA 4HRFA 2NZ6A 2J16A 3QCIA 4KYQA 1LARA 3N0AA 1T4JA 1OHEA 2P6XA 1PTUA 2CFVA 2CNFA 3QCBA 2H4KA 5K22A 1G7GA 3ZM2A 2J17A 2I6PA 4WOHA 4H34A 3F41A 2PA5A 2A8BA 2C46A 2I6IA 2I1YA 1KAVA 1A5YA 1J4XA 2PQ5A 5J8RA 4QBEA 2FJNA 3V0HA 2I6OA 5IBMA 1YTNA 5KA8A 1XRIA 1I9TA 2NT7A 4GFVA 2BIJA 1OHCA 1WAXA 1YTSA 2ZMMA 1NZ7A 3AWGA 1C84A 1PA9A 3S4EA 2CM3A 2GJTA 3O5XA 3I7ZA 1BZJA 1G4US 3ZM3A 3V0JA 5KA7A 1C86A 1NO6A 4YR8B 4Y2EA 2FH7A 3MOWA 1L8GA 2P4DA 2QCJA 3SR9A 2ZN7A 2F6YA 3V0IA 3QCCA 4DGXA 4YAAA 4R30A 4AZ1A 4RKKA 4QUMA 2AZRA 2RF6A 1XBOA 3F9BA 4OHLA 3QCGA 3D1HA 1LYVA 2QDMA 4J51A 4RHGA 1Q1MA 1YGUA 1R6HA 2B4UA 3RGOA 3QKPA 2B3OA 3O4UA 4H1OA 3V0GA 4GFUA 3EMUA 3F9AA 2F70A 2VEXA 2Y96A 4D3QA 1YPTA 5KA2A 2OZ5A 5MMZB 1Q6NA 2QDPA 1L8KA 5GTJA 1OEOX 3EZZA 2G6ZA 4ERCA 1SUGA 2HXPA 4D3PA 2B49A 1KAKA 1PYNA 2BV5A 2DXPA 2YDUA 1WRMA 1XM2A 1T48A 3QCEA 2F6WA 4OHDA 1BZCA 3S4OA 3QCFA 5K9WA 2VEWA 3RGQA 3SMEA 2CM7A 5EHPA 1P15A 2BZLA 1M3GA 4S0GA 2OUDA 2CNEA 4WTYA 2PT0A 4GE5A 3BM8A 3AWEA 2BGEA 3EU0A 4GRYA 5LXQB 2H4VA 3NMEA 3EB1A 3QCDA 2HY3A 1QZ0A 4GE6A 2F6VA 1PA1A 3GXGA 2VEVA 4GS0A 2I3RA 3ZMQA 4GWFA 4ZN5A 4KI9A 2BGDA 3RO1A 3D44A 4HJPA 5EHRA 3BLUA 4B04A 4Z6BA 2HC2A 3I36A 1PXHA 2SHPA 3QCNA 3ZV2A 1AAXA 1XXPA 4MBBA 3D42A 3MMJA 5BX1A 3EAXA 4NX8A 4JBCA 4WU3A 3QCJA 5KADA 2CJZA 1G1GA 1C85A 2CM2A 1OEMX 4TVVA 3ZM1A 4PYHA 3CM3A 1BZHA 2HB1A 1WCHA 3D1QA 3O3LA 1C83A 4QBWA 4PVGA 1YZ4A 2B4OA 3A5KA 4JMKA 1XXVA 1G4WR 2H4GA 5KA1A 5HDEA 1PH0A 3QKQA 2QBPA 2I4GA 2H03A 4R0SA 4ICZA 2CMBA 5BZZA 1V3AA 1I57A 5BZXA 2NV5A 1C87A 4BPCA 2B4PA 1QXKA 1YN9A 5KA3A 2PBNA 4ZI4A 1Q6TA 2HCMA 1GWZA 1NNYA 1PTVA 3QCMA 2CMAA 1U25A 3A5JA 2GP0A 4RI5A 2CNGA 3U96A 3CWEA 2H02A 4R0TA 4OHIA 4Y14A 5KA0A 1EENA 2HNPA 1JF7A 1GFYA 3PS5A 2IMGA 1RXDA 2QBSA 1ZCLA 1PTYA 3O4SA 1G1HA 4NNDA 2NTAA 2CNIA 2QCTA 2H04A 3BLTA 2CMCA 4QAPA 1X24A 1Q6MA 3I80A 2WGPA 2MBCA 3OMHA 5M43A 1T49A 2VEYA 3GXHA 3H2XA 4BJOA 4WU2A 2CM8A 1ONZA 5AWXA 4JNBA 2F46A 1Q6SA 2I42A 2Q05A 2QEPA 2NT2A 1NWLA 5K25A 2R0BA 4RH9A 1I9SA 2B4SA 3QCKA 3S3KA 2I5XA 1ONYA 1NWEA 4OHEA 3F81A 5KABA 5KACA 3OLRA 3D1OA 2I4HA 3V0FA 1ZZWA 1ECVA 5BUGA 2I6JA 4JMJA 5I6VA 4HJQA 3F99A 5K24A 1Q6JA 1YGRA 2AHSA 4NWGA 4NYHA 2PI7A 1U24A 4GRZA 4D3RA 3AWFA 2A3KA 2E0TA 1FPZA 2J16B 2B07A 4NWFA 5KA4A 5K23A 1JLNA 1FQ1A 4QAHA 3O4TA 3V0DA 1OHDA 1OEVA 2I6MA 2Y2FA 3B7OA 3ZM0A 3RZ2A 2NLKA 2I75A 4ZRTA 2F71A 2QDCA 2G59A 2GWOA 1YFOA 2I4EA 2F6TA 1MKPA 4OHHA 2QBQA 2M3VA 3LJ8A 4RI4A 1G1FA 3M4UA 1FPRA 1C88A 2C7SA 2ESBA 2F6ZA 2I3UA 1EEOA 4QUNA 1OESA
chains in the Genus database with same CATH superfamily
3MOZA 2PSZA 1ZC0A 2Y66A 2FJMA 4GE2A 2GCAA 1OETA 2HVLA 1Q6PA 3MVNA 1VHRA 2HC1A 3QCLA 3ZMPA 5K9VA 3S3HA 1NL9A 2OOQA 1ZCKA 4IKCA 1LQFA 1G7FA 5IBSA 4DGPA 1FGSA 5KA9A 3S3FA 5KAAA 2CNHA 2OC3A 2Q47A 2HNQA 3QCHA 3BRHA 1D5RA 1PTTA 4RDDA 3D9CA 3S3EA 1JBVA 4I8NA 1YWFA 2F6FA 3V0EA 1YTWA 2VEUA 4KYRA 4RH5A 1U26A 2JJDA 2QBRA 4QDIA 1RPMA 1OEUA 4HRFA 2NZ6A 2J16A 3QCIA 4KYQA 1LARA 3N0AA 1T4JA 1OHEA 2P6XA 2WJPA 4CVKA 1W7KA 1PTUA 2CFVA 2CNFA 3QCBA 1GG4A 2H4KA 5K22A 1G7GA 3ZM2A 2J17A 2I6PA 1E0DA 1W78A 4WOHA 4H34A 3F41A 2PA5A 2A8BA 2C46A 2I6IA 2I1YA 2PQ5A 1KAVA 1A5YA 1J4XA 5J8RA 4QBEA 2FJNA 3V0HA 2I6OA 2VOSA 5IBMA 1YTNA 5KA8A 1XRIA 1I9TA 2NT7A 4GFVA 2BIJA 1OHCA 1WAXA 3ZL8A 1YTSA 2ZMMA 1NZ7A 3AWGA 1C84A 1PA9A 3S4EA 2CM3A 2GJTA 3O5XA 3I7ZA 1BZJA 1G4US 3ZM3A 3V0JA 5KA7A 1C86A 1NO6A 4YR8B 4Y2EA 2FH7A 3MOWA 1L8GA 2P4DA 2Y1OA 2GC6A 1P31A 2QCJA 3SR9A 2ZN7A 2F6YA 3V0IA 3QCCA 4DGXA 4YAAA 4R30A 4AZ1A 4RKKA 4QUMA 2AZRA 4QF5A 2RF6A 1XBOA 3F9BA 4OHLA 3QCGA 3D1HA 1LYVA 2QDMA 4J51A 4RHGA 1Q1MA 1YGUA 1R6HA 2B4UA 3RGOA 3QKPA 2B3OA 2UAGA 2X5OA 3O4UA 4H1OA 3V0GA 4GFUA 3EMUA 4CVLA 1UAGA 3F9AA 2F70A 2VEXA 2Y96A 4D3QA 2JFGA 1YPTA 5KA2A 2OZ5A 5MMZB 1Q6NA 2QDPA 1L8KA 5GTJA 1OEOX 3EZZA 2G6ZA 4ERCA 1SUGA 2HXPA 4D3PA 2B49A 2F00A 1KAKA 1PYNA 2BV5A 2DXPA 2YDUA 4HV4A 4CVMA 1WRMA 5A5EA 1XM2A 1T48A 3QCEA 2F6WA 4OHDA 1BZCA 3S4OA 3QCZA 3QCFA 5K9WA 2VEWA 3RGQA 4BUBA 3SMEA 2CM7A 5EHPA 1P15A 2BZLA 1M3GA 4S0GA 2OUDA 2VTEA 2CNEA 4WTYA 2PT0A 4GE5A 3BM8A 3AWEA 2BGEA 2Y67A 3EU0A 4GRYA 5LXQB 2H4VA 3NMEA 3EB1A 3QCDA 1GQYA 2HY3A 1QZ0A 4GE6A 2F6VA 1PA1A 3GXGA 1EEHA 2AM2A 4ZIYA 2VEVA 4GS0A 2I3RA 3ZMQA 4GWFA 4ZN5A 4KI9A 2BGDA 2GC5A 3RO1A 3D44A 4C13A 4HJPA 5EHRA 2XPCA 3BLUA 4B04A 4Z6BA 2HC2A 3I36A 2JFFA 1PXHA 3N2AA 2SHPA 3QCNA 3ZV2A 2XJAA 1AAXA 1XXPA 4MBBA 3D42A 3MMJA 5BX1A 3EAXA 4NX8A 4JBCA 4WU3A 3QCJA 5KADA 2CJZA 1G1GA 1C85A 2CM2A 1OEMX 4TVVA 3ZM1A 4PYHA 3CM3A 1BZHA 2HB1A 1WCHA 3D1QA 3O3LA 1C83A 4QBWA 4PVGA 1YZ4A 2JFHA 2B4OA 3A5KA 2Y68A 4JMKA 1XXVA 1G4WR 2H4GA 5KA1A 5HDEA 1PH0A 3QKQA 2QBPA 2I4GA 2H03A 4R0SA 4ICZA 2CMBA 5BZZA 1V3AA 1I57A 5BZXA 5A5FA 2NV5A 1C87A 4BPCA 2B4PA 1QXKA 1YN9A 5KA3A 2PBNA 4ZI4A 1Q6TA 2HCMA 1GWZA 1NNYA 1PTVA 1O5ZA 3QCMA 2CMAA 1U25A 3A5JA 2GP0A 3NRSA 4RI5A 2CNGA 3U96A 3CWEA 2H02A 4R0TA 4OHIA 4Y14A 5KA0A 1EENA 1E8CA 2HNPA 1J6UA 1JF7A 1GFYA 3PS5A 2IMGA 1GQQA 1RXDA 4UAGA 2QBSA 1ZCLA 1PTYA 3O4SA 2AM1A 1G1HA 4NNDA 2NTAA 2CNIA 2QCTA 2H04A 3BLTA 2CMCA 4QAPA 1X24A 1Q6MA 3I80A 2WGPA 2MBCA 3OMHA 5M43A 1T49A 2VEYA 3GXHA 3H2XA 3ZM5A 2UUOA 4BJOA 4WU2A 2CM8A 1ONZA 5AWXA 4JNBA 2F46A 1Q6SA 2I42A 2Q05A 2QEPA 2NT2A 1NWLA 5K25A 2R0BA 4RH9A 2WTZA 1I9SA 2B4SA 3QCKA 3S3KA 2I5XA 1ONYA 1NWEA 3HN7A 4C12A 4OHEA 3F81A 5KABA 5KACA 3OLRA 3D1OA 2I4HA 3V0FA 1ZZWA 1ECVA 5BUGA 2I6JA 4JMJA 5I6VA 4HJQA 3F99A 5K24A 1Q6JA 1YGRA 2AHSA 4NWGA 3UAGA 4NYHA 2PI7A 1U24A 4GRZA 4D3RA 3AWFA 2A3KA 2E0TA 1FPZA 2J16B 2B07A 4NWFA 5KA4A 2VORA 5K23A 1JLNA 1FQ1A 4QAHA 2GCBA 3O4TA 1OHDA 3V0DA 1OEVA 2UUPA 4BUCA 2I6MA 2Y2FA 3B7OA 3ZM0A 3RZ2A 2NLKA 2I75A 3LK7A 4ZRTA 2F71A 2QDCA 2G59A 2GWOA 1YFOA 3PYZA 2VTDA 2I4EA 2F6TA 1MKPA 4OHHA 2QBQA 2M3VA 3LJ8A 4RI4A 1P3DA 1G1FA 3M4UA 3ZM6A 1FPRA 1C88A 1JBWA 2C7SA 2ESBA 2F6ZA 2I3UA 1EEOA 4QUNA 1OESA
chains in the Genus database with same CATH topology
3MOZA 2PSZA 1ZC0A 2FJMA 4GE2A 1OETA 2HVLA 1Q6PA 1VHRA 2HC1A 3QCLA 3ZMPA 5K9VA 3S3HA 1NL9A 2OOQA 1ZCKA 4IKCA 1LQFA 1G7FA 5IBSA 4DGPA 5KA9A 3S3FA 5KAAA 2CNHA 2OC3A 2Q47A 2HNQA 3QCHA 3BRHA 1D5RA 1PTTA 4RDDA 3D9CA 3S3EA 4I8NA 1YWFA 2F6FA 3V0EA 1YTWA 2VEUA 4KYRA 4RH5A 1U26A 2JJDA 2QBRA 1RPMA 1OEUA 4HRFA 2NZ6A 2J16A 3QCIA 4KYQA 1LARA 3N0AA 1T4JA 1OHEA 2P6XA 1PTUA 2CFVA 2CNFA 3QCBA 2H4KA 5K22A 1G7GA 3ZM2A 2J17A 2I6PA 4WOHA 4H34A 3F41A 2PA5A 2A8BA 2C46A 2I6IA 2I1YA 1KAVA 1A5YA 1J4XA 2PQ5A 5J8RA 4QBEA 2FJNA 3V0HA 2I6OA 5IBMA 1YTNA 5KA8A 1XRIA 1I9TA 2NT7A 4GFVA 2BIJA 1OHCA 1WAXA 1YTSA 2ZMMA 1NZ7A 3AWGA 1C84A 1PA9A 3S4EA 2CM3A 2GJTA 3O5XA 3I7ZA 1BZJA 1G4US 3ZM3A 3V0JA 5KA7A 1C86A 1NO6A 4YR8B 4Y2EA 2FH7A 3MOWA 1L8GA 2P4DA 2QCJA 3SR9A 2ZN7A 2F6YA 3V0IA 3QCCA 4DGXA 4YAAA 4R30A 4AZ1A 4RKKA 4QUMA 2AZRA 2RF6A 1XBOA 3F9BA 4OHLA 3QCGA 3D1HA 1LYVA 2QDMA 4J51A 4RHGA 1Q1MA 1YGUA 1R6HA 2B4UA 3RGOA 3QKPA 2B3OA 3O4UA 4H1OA 3V0GA 4GFUA 3EMUA 3F9AA 2F70A 2VEXA 2Y96A 4D3QA 1YPTA 5KA2A 2OZ5A 5MMZB 1Q6NA 2QDPA 1L8KA 5GTJA 1OEOX 3EZZA 2G6ZA 4ERCA 1SUGA 2HXPA 4D3PA 2B49A 1KAKA 1PYNA 2BV5A 2DXPA 2YDUA 1WRMA 1XM2A 1T48A 3QCEA 2F6WA 4OHDA 1BZCA 3S4OA 3QCFA 5K9WA 2VEWA 3RGQA 3SMEA 2CM7A 5EHPA 1P15A 2BZLA 1M3GA 4S0GA 2OUDA 2CNEA 4WTYA 2PT0A 4GE5A 3BM8A 3AWEA 2BGEA 3EU0A 4GRYA 5LXQB 2H4VA 3NMEA 3EB1A 3QCDA 2HY3A 1QZ0A 4GE6A 2F6VA 1PA1A 3GXGA 2VEVA 4GS0A 2I3RA 3ZMQA 4GWFA 4ZN5A 4KI9A 2BGDA 3RO1A 3D44A 4HJPA 5EHRA 3BLUA 4B04A 4Z6BA 2HC2A 3I36A 1PXHA 2SHPA 3QCNA 3ZV2A 1AAXA 1XXPA 4MBBA 3D42A 3MMJA 5BX1A 3EAXA 4NX8A 4JBCA 4WU3A 3QCJA 5KADA 2CJZA 1G1GA 1C85A 2CM2A 1OEMX 4TVVA 3ZM1A 4PYHA 3CM3A 1BZHA 2HB1A 1WCHA 3D1QA 3O3LA 1C83A 4QBWA 4PVGA 1YZ4A 2B4OA 3A5KA 4JMKA 1XXVA 1G4WR 2H4GA 5KA1A 5HDEA 1PH0A 3QKQA 2QBPA 2I4GA 2H03A 4R0SA 4ICZA 2CMBA 5BZZA 1V3AA 1I57A 5BZXA 2NV5A 1C87A 4BPCA 2B4PA 1QXKA 1YN9A 5KA3A 2PBNA 4ZI4A 1Q6TA 2HCMA 1GWZA 1NNYA 1PTVA 3QCMA 2CMAA 1U25A 3A5JA 2GP0A 4RI5A 2CNGA 3U96A 3CWEA 2H02A 4R0TA 4OHIA 4Y14A 5KA0A 1EENA 2HNPA 1JF7A 1GFYA 3PS5A 2IMGA 1RXDA 2QBSA 1ZCLA 1PTYA 3O4SA 1G1HA 4NNDA 2NTAA 2CNIA 2QCTA 2H04A 3BLTA 2CMCA 4QAPA 1X24A 1Q6MA 3I80A 2WGPA 2MBCA 3OMHA 5M43A 1T49A 2VEYA 3GXHA 3H2XA 4BJOA 4WU2A 2CM8A 1ONZA 5AWXA 4JNBA 2F46A 1Q6SA 2I42A 2Q05A 2QEPA 2NT2A 1NWLA 5K25A 2R0BA 4RH9A 1I9SA 2B4SA 3QCKA 3S3KA 2I5XA 1ONYA 1NWEA 4OHEA 3F81A 5KABA 5KACA 3OLRA 3D1OA 2I4HA 3V0FA 1ZZWA 1ECVA 5BUGA 2I6JA 4JMJA 5I6VA 4HJQA 3F99A 5K24A 1Q6JA 1YGRA 2AHSA 4NWGA 4NYHA 2PI7A 1U24A 4GRZA 4D3RA 3AWFA 2A3KA 2E0TA 1FPZA 2J16B 2B07A 4NWFA 5KA4A 5K23A 1JLNA 1FQ1A 4QAHA 3O4TA 3V0DA 1OHDA 1OEVA 2I6MA 2Y2FA 3B7OA 3ZM0A 3RZ2A 2NLKA 2I75A 4ZRTA 2F71A 2QDCA 2G59A 2GWOA 1YFOA 2I4EA 2F6TA 1MKPA 4OHHA 2QBQA 2M3VA 3LJ8A 4RI4A 1G1FA 3M4UA 1FPRA 1C88A 2C7SA 2ESBA 2F6ZA 2I3UA 1EEOA 4QUNA 1OESA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MOZ A;  2PSZ A;  1ZC0 A;  2FJM A;  4GE2 A;  1OET A;  2HVL A;  1Q6P A;  1VHR A;  2HC1 A;  3QCL A;  3ZMP A;  5K9V A;  3S3H A;  1NL9 A;  2OOQ A;  1ZCK A;  4IKC A;  1LQF A;  1G7F A;  5IBS A;  4DGP A;  5KA9 A;  3S3F A;  5KAA A;  2CNH A;  2OC3 A;  2Q47 A;  2HNQ A;  3QCH A;  3BRH A;  1D5R A;  1PTT A;  4RDD A;  3D9C A;  3S3E A;  4I8N A;  1YWF A;  2F6F A;  3V0E A;  1YTW A;  2VEU A;  4KYR A;  4RH5 A;  1U26 A;  2JJD A;  2QBR A;  1RPM A;  1OEU A;  4HRF A;  2NZ6 A;  2J16 A;  3QCI A;  4KYQ A;  1LAR A;  3N0A A;  1T4J A;  1OHE A;  2P6X A;  1PTU A;  2CFV A;  2CNF A;  3QCB A;  2H4K A;  5K22 A;  1G7G A;  3ZM2 A;  2J17 A;  2I6P A;  4WOH A;  4H34 A;  3F41 A;  2PA5 A;  2A8B A;  2C46 A;  2I6I A;  2I1Y A;  1KAV A;  1A5Y A;  1J4X A;  2PQ5 A;  5J8R A;  4QBE A;  2FJN A;  3V0H A;  2I6O A;  5IBM A;  1YTN A;  5KA8 A;  1XRI A;  1I9T A;  2NT7 A;  4GFV A;  2BIJ A;  1OHC A;  1WAX A;  1YTS A;  2ZMM A;  1NZ7 A;  3AWG A;  1C84 A;  1PA9 A;  3S4E A;  2CM3 A;  2GJT A;  3O5X A;  3I7Z A;  1BZJ A;  1G4U S;  3ZM3 A;  3V0J A;  5KA7 A;  1C86 A;  1NO6 A;  4YR8 B;  4Y2E A;  2FH7 A;  3MOW A;  1L8G A;  2P4D A;  2QCJ A;  3SR9 A;  2ZN7 A;  2F6Y A;  3V0I A;  3QCC A;  4DGX A;  4YAA A;  4R30 A;  4AZ1 A;  4RKK A;  4QUM A;  2AZR A;  2RF6 A;  1XBO A;  3F9B A;  4OHL A;  3QCG A;  3D1H A;  1LYV A;  2QDM A;  4J51 A;  4RHG A;  1Q1M A;  1YGU A;  1R6H A;  2B4U A;  3RGO A;  3QKP A;  2B3O A;  3O4U A;  4H1O A;  3V0G A;  4GFU A;  3EMU A;  3F9A A;  2F70 A;  2VEX A;  2Y96 A;  4D3Q A;  1YPT A;  5KA2 A;  2OZ5 A;  5MMZ B;  1Q6N A;  2QDP A;  1L8K A;  5GTJ A;  1OEO X;  3EZZ A;  2G6Z A;  4ERC A;  1SUG A;  2HXP A;  4D3P A;  2B49 A;  1KAK A;  1PYN A;  2BV5 A;  2DXP A;  2YDU A;  1WRM A;  1XM2 A;  1T48 A;  3QCE A;  2F6W A;  4OHD A;  1BZC A;  3S4O A;  3QCF A;  5K9W A;  2VEW A;  3RGQ A;  3SME A;  2CM7 A;  5EHP A;  1P15 A;  2BZL A;  1M3G A;  4S0G A;  2OUD A;  2CNE A;  4WTY A;  2PT0 A;  4GE5 A;  3BM8 A;  3AWE A;  2BGE A;  3EU0 A;  4GRY A;  5LXQ B;  2H4V A;  3NME A;  3EB1 A;  3QCD A;  2HY3 A;  1QZ0 A;  4GE6 A;  2F6V A;  1PA1 A;  3GXG A;  2VEV A;  4GS0 A;  2I3R A;  3ZMQ A;  4GWF A;  4ZN5 A;  4KI9 A;  2BGD A;  3RO1 A;  3D44 A;  4HJP A;  5EHR A;  3BLU A;  4B04 A;  4Z6B A;  2HC2 A;  3I36 A;  1PXH A;  2SHP A;  3QCN A;  3ZV2 A;  1AAX A;  1XXP A;  4MBB A;  3D42 A;  3MMJ A;  5BX1 A;  3EAX A;  4NX8 A;  4JBC A;  4WU3 A;  3QCJ A;  5KAD A;  2CJZ A;  1G1G A;  1C85 A;  2CM2 A;  1OEM X;  4TVV A;  3ZM1 A;  4PYH A;  3CM3 A;  1BZH A;  2HB1 A;  1WCH A;  3D1Q A;  3O3L A;  1C83 A;  4QBW A;  4PVG A;  1YZ4 A;  2B4O A;  3A5K A;  4JMK A;  1XXV A;  1G4W R;  2H4G A;  5KA1 A;  5HDE A;  1PH0 A;  3QKQ A;  2QBP A;  2I4G A;  2H03 A;  4R0S A;  4ICZ A;  2CMB A;  5BZZ A;  1V3A A;  1I57 A;  5BZX A;  2NV5 A;  1C87 A;  4BPC A;  2B4P A;  1QXK A;  1YN9 A;  5KA3 A;  2PBN A;  4ZI4 A;  1Q6T A;  2HCM A;  1GWZ A;  1NNY A;  1PTV A;  3QCM A;  2CMA A;  1U25 A;  3A5J A;  2GP0 A;  4RI5 A;  2CNG A;  3U96 A;  3CWE A;  2H02 A;  4R0T A;  4OHI A;  4Y14 A;  5KA0 A;  1EEN A;  2HNP A;  1JF7 A;  1GFY A;  3PS5 A;  2IMG A;  1RXD A;  2QBS A;  1ZCL A;  1PTY A;  3O4S A;  1G1H A;  4NND A;  2NTA A;  2CNI A;  2QCT A;  2H04 A;  3BLT A;  2CMC A;  4QAP A;  1X24 A;  1Q6M A;  3I80 A;  2WGP A;  2MBC A;  3OMH A;  5M43 A;  1T49 A;  2VEY A;  3GXH A;  3H2X A;  4BJO A;  4WU2 A;  2CM8 A;  1ONZ A;  5AWX A;  4JNB A;  2F46 A;  1Q6S A;  2I42 A;  2Q05 A;  2QEP A;  2NT2 A;  1NWL A;  5K25 A;  2R0B A;  4RH9 A;  1I9S A;  2B4S A;  3QCK A;  3S3K A;  2I5X A;  1ONY A;  1NWE A;  4OHE A;  3F81 A;  5KAB A;  5KAC A;  3OLR A;  3D1O A;  2I4H A;  3V0F A;  1ZZW A;  1ECV A;  5BUG A;  2I6J A;  4JMJ A;  5I6V A;  4HJQ A;  3F99 A;  5K24 A;  1Q6J A;  1YGR A;  2AHS A;  4NWG A;  4NYH A;  2PI7 A;  1U24 A;  4GRZ A;  4D3R A;  3AWF A;  2A3K A;  2E0T A;  1FPZ A;  2J16 B;  2B07 A;  4NWF A;  5KA4 A;  5K23 A;  1JLN A;  1FQ1 A;  4QAH A;  3O4T A;  3V0D A;  1OHD A;  1OEV A;  2I6M A;  2Y2F A;  3B7O A;  3ZM0 A;  3RZ2 A;  2NLK A;  2I75 A;  4ZRT A;  2F71 A;  2QDC A;  2G59 A;  2GWO A;  1YFO A;  2I4E A;  2F6T A;  1MKP A;  4OHH A;  2QBQ A;  2M3V A;  3LJ8 A;  4RI4 A;  1G1F A;  3M4U A;  1FPR A;  1C88 A;  2C7S A;  2ESB A;  2F6Z A;  2I3U A;  1EEO A;  4QUN A;  1OES A; 
#chains in the Genus database with same CATH topology
 3MOZ A;  2PSZ A;  1ZC0 A;  2Y66 A;  2FJM A;  4GE2 A;  2GCA A;  1OET A;  2HVL A;  1Q6P A;  3MVN A;  1VHR A;  2HC1 A;  3QCL A;  3ZMP A;  5K9V A;  3S3H A;  1NL9 A;  2OOQ A;  1ZCK A;  4IKC A;  1LQF A;  1G7F A;  5IBS A;  4DGP A;  1FGS A;  5KA9 A;  3S3F A;  5KAA A;  2CNH A;  2OC3 A;  2Q47 A;  2HNQ A;  3QCH A;  3BRH A;  1D5R A;  1PTT A;  4RDD A;  3D9C A;  3S3E A;  1JBV A;  4I8N A;  1YWF A;  2F6F A;  3V0E A;  1YTW A;  2VEU A;  4KYR A;  4RH5 A;  1U26 A;  2JJD A;  2QBR A;  4QDI A;  1RPM A;  1OEU A;  4HRF A;  2NZ6 A;  2J16 A;  3QCI A;  4KYQ A;  1LAR A;  3N0A A;  1T4J A;  1OHE A;  2P6X A;  2WJP A;  4CVK A;  1W7K A;  1PTU A;  2CFV A;  2CNF A;  3QCB A;  1GG4 A;  2H4K A;  5K22 A;  1G7G A;  3ZM2 A;  2J17 A;  2I6P A;  1E0D A;  1W78 A;  4WOH A;  4H34 A;  3F41 A;  2PA5 A;  2A8B A;  2C46 A;  2I6I A;  2I1Y A;  2PQ5 A;  1KAV A;  1A5Y A;  1J4X A;  5J8R A;  4QBE A;  2FJN A;  3V0H A;  2I6O A;  2VOS A;  5IBM A;  1YTN A;  5KA8 A;  1XRI A;  1I9T A;  2NT7 A;  4GFV A;  2BIJ A;  1OHC A;  1WAX A;  3ZL8 A;  1YTS A;  2ZMM A;  1NZ7 A;  3AWG A;  1C84 A;  1PA9 A;  3S4E A;  2CM3 A;  2GJT A;  3O5X A;  3I7Z A;  1BZJ A;  1G4U S;  3ZM3 A;  3V0J A;  5KA7 A;  1C86 A;  1NO6 A;  4YR8 B;  4Y2E A;  2FH7 A;  3MOW A;  1L8G A;  2P4D A;  2Y1O A;  2GC6 A;  1P31 A;  2QCJ A;  3SR9 A;  2ZN7 A;  2F6Y A;  3V0I A;  3QCC A;  4DGX A;  4YAA A;  4R30 A;  4AZ1 A;  4RKK A;  4QUM A;  2AZR A;  4QF5 A;  2RF6 A;  1XBO A;  3F9B A;  4OHL A;  3QCG A;  3D1H A;  1LYV A;  2QDM A;  4J51 A;  4RHG A;  1Q1M A;  1YGU A;  1R6H A;  2B4U A;  3RGO A;  3QKP A;  2B3O A;  2UAG A;  2X5O A;  3O4U A;  4H1O A;  3V0G A;  4GFU A;  3EMU A;  4CVL A;  1UAG A;  3F9A A;  2F70 A;  2VEX A;  2Y96 A;  4D3Q A;  2JFG A;  1YPT A;  5KA2 A;  2OZ5 A;  5MMZ B;  1Q6N A;  2QDP A;  1L8K A;  5GTJ A;  1OEO X;  3EZZ A;  2G6Z A;  4ERC A;  1SUG A;  2HXP A;  4D3P A;  2B49 A;  2F00 A;  1KAK A;  1PYN A;  2BV5 A;  2DXP A;  2YDU A;  4HV4 A;  4CVM A;  1WRM A;  5A5E A;  1XM2 A;  1T48 A;  3QCE A;  2F6W A;  4OHD A;  1BZC A;  3S4O A;  3QCZ A;  3QCF A;  5K9W A;  2VEW A;  3RGQ A;  4BUB A;  3SME A;  2CM7 A;  5EHP A;  1P15 A;  2BZL A;  1M3G A;  4S0G A;  2OUD A;  2VTE A;  2CNE A;  4WTY A;  2PT0 A;  4GE5 A;  3BM8 A;  3AWE A;  2BGE A;  2Y67 A;  3EU0 A;  4GRY A;  5LXQ B;  2H4V A;  3NME A;  3EB1 A;  3QCD A;  1GQY A;  2HY3 A;  1QZ0 A;  4GE6 A;  2F6V A;  1PA1 A;  3GXG A;  1EEH A;  2AM2 A;  4ZIY A;  2VEV A;  4GS0 A;  2I3R A;  3ZMQ A;  4GWF A;  4ZN5 A;  4KI9 A;  2BGD A;  2GC5 A;  3RO1 A;  3D44 A;  4C13 A;  4HJP A;  5EHR A;  2XPC A;  3BLU A;  4B04 A;  4Z6B A;  2HC2 A;  3I36 A;  2JFF A;  1PXH A;  3N2A A;  2SHP A;  3QCN A;  3ZV2 A;  2XJA A;  1AAX A;  1XXP A;  4MBB A;  3D42 A;  3MMJ A;  5BX1 A;  3EAX A;  4NX8 A;  4JBC A;  4WU3 A;  3QCJ A;  5KAD A;  2CJZ A;  1G1G A;  1C85 A;  2CM2 A;  1OEM X;  4TVV A;  3ZM1 A;  4PYH A;  3CM3 A;  1BZH A;  2HB1 A;  1WCH A;  3D1Q A;  3O3L A;  1C83 A;  4QBW A;  4PVG A;  1YZ4 A;  2JFH A;  2B4O A;  3A5K A;  2Y68 A;  4JMK A;  1XXV A;  1G4W R;  2H4G A;  5KA1 A;  5HDE A;  1PH0 A;  3QKQ A;  2QBP A;  2I4G A;  2H03 A;  4R0S A;  4ICZ A;  2CMB A;  5BZZ A;  1V3A A;  1I57 A;  5BZX A;  5A5F A;  2NV5 A;  1C87 A;  4BPC A;  2B4P A;  1QXK A;  1YN9 A;  5KA3 A;  2PBN A;  4ZI4 A;  1Q6T A;  2HCM A;  1GWZ A;  1NNY A;  1PTV A;  1O5Z A;  3QCM A;  2CMA A;  1U25 A;  3A5J A;  2GP0 A;  3NRS A;  4RI5 A;  2CNG A;  3U96 A;  3CWE A;  2H02 A;  4R0T A;  4OHI A;  4Y14 A;  5KA0 A;  1EEN A;  1E8C A;  2HNP A;  1J6U A;  1JF7 A;  1GFY A;  3PS5 A;  2IMG A;  1GQQ A;  1RXD A;  4UAG A;  2QBS A;  1ZCL A;  1PTY A;  3O4S A;  2AM1 A;  1G1H A;  4NND A;  2NTA A;  2CNI A;  2QCT A;  2H04 A;  3BLT A;  2CMC A;  4QAP A;  1X24 A;  1Q6M A;  3I80 A;  2WGP A;  2MBC A;  3OMH A;  5M43 A;  1T49 A;  2VEY A;  3GXH A;  3H2X A;  3ZM5 A;  2UUO A;  4BJO A;  4WU2 A;  2CM8 A;  1ONZ A;  5AWX A;  4JNB A;  2F46 A;  1Q6S A;  2I42 A;  2Q05 A;  2QEP A;  2NT2 A;  1NWL A;  5K25 A;  2R0B A;  4RH9 A;  2WTZ A;  1I9S A;  2B4S A;  3QCK A;  3S3K A;  2I5X A;  1ONY A;  1NWE A;  3HN7 A;  4C12 A;  4OHE A;  3F81 A;  5KAB A;  5KAC A;  3OLR A;  3D1O A;  2I4H A;  3V0F A;  1ZZW A;  1ECV A;  5BUG A;  2I6J A;  4JMJ A;  5I6V A;  4HJQ A;  3F99 A;  5K24 A;  1Q6J A;  1YGR A;  2AHS A;  4NWG A;  3UAG A;  4NYH A;  2PI7 A;  1U24 A;  4GRZ A;  4D3R A;  3AWF A;  2A3K A;  2E0T A;  1FPZ A;  2J16 B;  2B07 A;  4NWF A;  5KA4 A;  2VOR A;  5K23 A;  1JLN A;  1FQ1 A;  4QAH A;  2GCB A;  3O4T A;  1OHD A;  3V0D A;  1OEV A;  2UUP A;  4BUC A;  2I6M A;  2Y2F A;  3B7O A;  3ZM0 A;  3RZ2 A;  2NLK A;  2I75 A;  3LK7 A;  4ZRT A;  2F71 A;  2QDC A;  2G59 A;  2GWO A;  1YFO A;  3PYZ A;  2VTD A;  2I4E A;  2F6T A;  1MKP A;  4OHH A;  2QBQ A;  2M3V A;  3LJ8 A;  4RI4 A;  1P3D A;  1G1F A;  3M4U A;  3ZM6 A;  1FPR A;  1C88 A;  1JBW A;  2C7S A;  2ESB A;  2F6Z A;  2I3U A;  1EEO A;  4QUN A;  1OES A; 
#chains in the Genus database with same CATH homology
 3MOZ A;  2PSZ A;  1ZC0 A;  2FJM A;  4GE2 A;  1OET A;  2HVL A;  1Q6P A;  1VHR A;  2HC1 A;  3QCL A;  3ZMP A;  5K9V A;  3S3H A;  1NL9 A;  2OOQ A;  1ZCK A;  4IKC A;  1LQF A;  1G7F A;  5IBS A;  4DGP A;  5KA9 A;  3S3F A;  5KAA A;  2CNH A;  2OC3 A;  2Q47 A;  2HNQ A;  3QCH A;  3BRH A;  1D5R A;  1PTT A;  4RDD A;  3D9C A;  3S3E A;  4I8N A;  1YWF A;  2F6F A;  3V0E A;  1YTW A;  2VEU A;  4KYR A;  4RH5 A;  1U26 A;  2JJD A;  2QBR A;  1RPM A;  1OEU A;  4HRF A;  2NZ6 A;  2J16 A;  3QCI A;  4KYQ A;  1LAR A;  3N0A A;  1T4J A;  1OHE A;  2P6X A;  1PTU A;  2CFV A;  2CNF A;  3QCB A;  2H4K A;  5K22 A;  1G7G A;  3ZM2 A;  2J17 A;  2I6P A;  4WOH A;  4H34 A;  3F41 A;  2PA5 A;  2A8B A;  2C46 A;  2I6I A;  2I1Y A;  1KAV A;  1A5Y A;  1J4X A;  2PQ5 A;  5J8R A;  4QBE A;  2FJN A;  3V0H A;  2I6O A;  5IBM A;  1YTN A;  5KA8 A;  1XRI A;  1I9T A;  2NT7 A;  4GFV A;  2BIJ A;  1OHC A;  1WAX A;  1YTS A;  2ZMM A;  1NZ7 A;  3AWG A;  1C84 A;  1PA9 A;  3S4E A;  2CM3 A;  2GJT A;  3O5X A;  3I7Z A;  1BZJ A;  1G4U S;  3ZM3 A;  3V0J A;  5KA7 A;  1C86 A;  1NO6 A;  4YR8 B;  4Y2E A;  2FH7 A;  3MOW A;  1L8G A;  2P4D A;  2QCJ A;  3SR9 A;  2ZN7 A;  2F6Y A;  3V0I A;  3QCC A;  4DGX A;  4YAA A;  4R30 A;  4AZ1 A;  4RKK A;  4QUM A;  2AZR A;  2RF6 A;  1XBO A;  3F9B A;  4OHL A;  3QCG A;  3D1H A;  1LYV A;  2QDM A;  4J51 A;  4RHG A;  1Q1M A;  1YGU A;  1R6H A;  2B4U A;  3RGO A;  3QKP A;  2B3O A;  3O4U A;  4H1O A;  3V0G A;  4GFU A;  3EMU A;  3F9A A;  2F70 A;  2VEX A;  2Y96 A;  4D3Q A;  1YPT A;  5KA2 A;  2OZ5 A;  5MMZ B;  1Q6N A;  2QDP A;  1L8K A;  5GTJ A;  1OEO X;  3EZZ A;  2G6Z A;  4ERC A;  1SUG A;  2HXP A;  4D3P A;  2B49 A;  1KAK A;  1PYN A;  2BV5 A;  2DXP A;  2YDU A;  1WRM A;  1XM2 A;  1T48 A;  3QCE A;  2F6W A;  4OHD A;  1BZC A;  3S4O A;  3QCF A;  5K9W A;  2VEW A;  3RGQ A;  3SME A;  2CM7 A;  5EHP A;  1P15 A;  2BZL A;  1M3G A;  4S0G A;  2OUD A;  2CNE A;  4WTY A;  2PT0 A;  4GE5 A;  3BM8 A;  3AWE A;  2BGE A;  3EU0 A;  4GRY A;  5LXQ B;  2H4V A;  3NME A;  3EB1 A;  3QCD A;  2HY3 A;  1QZ0 A;  4GE6 A;  2F6V A;  1PA1 A;  3GXG A;  2VEV A;  4GS0 A;  2I3R A;  3ZMQ A;  4GWF A;  4ZN5 A;  4KI9 A;  2BGD A;  3RO1 A;  3D44 A;  4HJP A;  5EHR A;  3BLU A;  4B04 A;  4Z6B A;  2HC2 A;  3I36 A;  1PXH A;  2SHP A;  3QCN A;  3ZV2 A;  1AAX A;  1XXP A;  4MBB A;  3D42 A;  3MMJ A;  5BX1 A;  3EAX A;  4NX8 A;  4JBC A;  4WU3 A;  3QCJ A;  5KAD A;  2CJZ A;  1G1G A;  1C85 A;  2CM2 A;  1OEM X;  4TVV A;  3ZM1 A;  4PYH A;  3CM3 A;  1BZH A;  2HB1 A;  1WCH A;  3D1Q A;  3O3L A;  1C83 A;  4QBW A;  4PVG A;  1YZ4 A;  2B4O A;  3A5K A;  4JMK A;  1XXV A;  1G4W R;  2H4G A;  5KA1 A;  5HDE A;  1PH0 A;  3QKQ A;  2QBP A;  2I4G A;  2H03 A;  4R0S A;  4ICZ A;  2CMB A;  5BZZ A;  1V3A A;  1I57 A;  5BZX A;  2NV5 A;  1C87 A;  4BPC A;  2B4P A;  1QXK A;  1YN9 A;  5KA3 A;  2PBN A;  4ZI4 A;  1Q6T A;  2HCM A;  1GWZ A;  1NNY A;  1PTV A;  3QCM A;  2CMA A;  1U25 A;  3A5J A;  2GP0 A;  4RI5 A;  2CNG A;  3U96 A;  3CWE A;  2H02 A;  4R0T A;  4OHI A;  4Y14 A;  5KA0 A;  1EEN A;  2HNP A;  1JF7 A;  1GFY A;  3PS5 A;  2IMG A;  1RXD A;  2QBS A;  1ZCL A;  1PTY A;  3O4S A;  1G1H A;  4NND A;  2NTA A;  2CNI A;  2QCT A;  2H04 A;  3BLT A;  2CMC A;  4QAP A;  1X24 A;  1Q6M A;  3I80 A;  2WGP A;  2MBC A;  3OMH A;  5M43 A;  1T49 A;  2VEY A;  3GXH A;  3H2X A;  4BJO A;  4WU2 A;  2CM8 A;  1ONZ A;  5AWX A;  4JNB A;  2F46 A;  1Q6S A;  2I42 A;  2Q05 A;  2QEP A;  2NT2 A;  1NWL A;  5K25 A;  2R0B A;  4RH9 A;  1I9S A;  2B4S A;  3QCK A;  3S3K A;  2I5X A;  1ONY A;  1NWE A;  4OHE A;  3F81 A;  5KAB A;  5KAC A;  3OLR A;  3D1O A;  2I4H A;  3V0F A;  1ZZW A;  1ECV A;  5BUG A;  2I6J A;  4JMJ A;  5I6V A;  4HJQ A;  3F99 A;  5K24 A;  1Q6J A;  1YGR A;  2AHS A;  4NWG A;  4NYH A;  2PI7 A;  1U24 A;  4GRZ A;  4D3R A;  3AWF A;  2A3K A;  2E0T A;  1FPZ A;  2J16 B;  2B07 A;  4NWF A;  5KA4 A;  5K23 A;  1JLN A;  1FQ1 A;  4QAH A;  3O4T A;  3V0D A;  1OHD A;  1OEV A;  2I6M A;  2Y2F A;  3B7O A;  3ZM0 A;  3RZ2 A;  2NLK A;  2I75 A;  4ZRT A;  2F71 A;  2QDC A;  2G59 A;  2GWO A;  1YFO A;  2I4E A;  2F6T A;  1MKP A;  4OHH A;  2QBQ A;  2M3V A;  3LJ8 A;  4RI4 A;  1G1F A;  3M4U A;  1FPR A;  1C88 A;  2C7S A;  2ESB A;  2F6Z A;  2I3U A;  1EEO A;  4QUN A;  1OES A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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