3QCMA

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-{[3-({n-[2-(methylamino)ethyl]glycyl}amino)phenyl]ethynyl}benzoic acid
Total Genus 99
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
299
structure length
286
Chain Sequence
MEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPLPGSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIIMITNLVEKGRRKCDQYWPTENTEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Receptor-type tyrosine-protein phosphatase gamma
total genus 99
structure length 286
sequence length 299
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2011-01-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3qcmA00
3CM3A 3QCGA 4HJQA 3D1OA 1NL9A 4DGXA 2PT0A 4R0SA 4ICZA 3O4TA 2I42A 2P6XA 4OHHA 5KABA 4QBWA 2I3RA 2B07A 4NWFA 2F70A 4GE5A 1NZ7A 1PYNA 2I4HA 2H03A 1OEOX 2AHSA 4KYRA 3ZMQA 1YN9A 1ZZWA 4R0TA 3QCHA 1WAXA 1OEVA 2H4GA 2PQ5A 3AWEA 1G4US 2NTAA 4Z6BA 3MOWA 1L8GA 5K9VA 5K23A 2NT2A 5HDEA 4H34A 2B3OA 5KA0A 1T4JA 2A8BA 4MBBA 3B7OA 3D9CA 4BPCA 3S4OA 4QUNA 3QCNA 5KA8A 1PTVA 1XBOA 4IKCA 2QBSA 3BRHA 3S3FA 3BLUA 2QDCA 2I6PA 4Y14A 3EAXA 4R30A 1C84A 3QCLA 2CNHA 4B04A 2WGPA 1U25A 3LJ8A 4DGPA 1JF7A 2OUDA 2CM8A 2VEXA 2OZ5A 2PSZA 1FPZA 1ZCLA 2NT7A 5BZXA 3V0IA 4WTYA 2FH7A 3EZZA 1Q1MA 3ZM1A 1YPTA 2J17A 5BX1A 4TVVA 1ZC0A 3I80A 4I8NA 2CNEA 2P4DA 2HNQA 3ZM0A 2B4OA 1WCHA 4ERCA 2F6YA 5AWXA 1JLNA 2BGEA 3F81A 4OHLA 2CJZA 2CM7A 1Q6TA 1YTSA 1LARA 3QKPA 3NMEA 1FPRA 1BZCA 1XXVA 5KA1A 3SR9A 1VHRA 4JMKA 2HXPA 2ZN7A 4OHDA 3PS5A 2HC1A 3S3HA 1NWEA 2CM2A 5KA9A 3V0HA 3D1HA 1OHEA 3AWGA 4AZ1A 1BZHA 5EHRA 4GRZA 4NWGA 2PBNA 2B4PA 4QBEA 2BIJA 2HVLA 5K25A 4S0GA 1U24A 2QBPA 3D42A 4WU2A 2AZRA 3QCJA 2QDMA 3BLTA 5K22A 2GJTA 4GE2A 1R6HA 3QCKA 1PTTA 1YFOA 1P15A 3QCEA 4YR8B 2F71A 2E0TA 2HC2A 1FQ1A 4JBCA 3ZM2A 2NZ6A 1AAXA 5K24A 1PXHA 2MBCA 1LYVA 1X24A 5GTJA 1BZJA 1ONZA 2SHPA 3BM8A 3QCIA 3I7ZA 1ZCKA 2BGDA 2Y2FA 5LXQB 1XRIA 1YGRA 1RPMA 2F6WA 1WRMA 2CNIA 2QBRA 3A5KA 5MMZB 2F6VA 2BZLA 2HNPA 1Q6MA 4RH5A 1OEUA 2QBQA 3V0DA 5KA7A 2B49A 4NYHA 2GWOA 5M43A 3D1QA 1XXPA 4BJOA 5KA4A 2H04A 2I4EA 3V0FA 5KA3A 2I5XA 1G1HA 4RI4A 4GRYA 2GP0A 1OEMX 2OC3A 3O3LA 2F6FA 2FJNA 1G7GA 2F46A 5K9WA 5KACA 3F9AA 3V0JA 4KI9A 1OESA 1PTUA 4YAAA 3I36A 1Q6JA 4D3RA 4H1OA 3QCMA 1C83A 1C87A 3GXHA 1GWZA 1I9TA 3S4EA 1Q6NA 1G7FA 5IBSA 2RF6A 5BUGA 2I75A 2JJDA 3QCFA 1OETA 2CFVA 3F99A 2I4GA 3O4UA 2CMBA 1YGUA 3ZM3A 1I9SA 1T49A 2BV5A 3O5XA 3EU0A 2DXPA 2G59A 1NO6A 2VEYA 1EEOA 1OHDA 1XM2A 1ECVA 3CWEA 4KYQA 3SMEA 2ESBA 1KAVA 1G4WR 1D5RA 3EB1A 3OMHA 3QCBA 2C7SA 5KADA 3F41A 3A5JA 2CNGA 1PH0A 1NNYA 2HB1A 2R0BA 4JNBA 2F6TA 5EHPA 1YWFA 1M3GA 2H4KA 2YDUA 2VEUA 4OHIA 3AWFA 4RDDA 4QUMA 1ONYA 3OLRA 4D3PA 2CMCA 3QKQA 5J8RA 4JMJA 3V0GA 1L8KA 1C86A 4ZN5A 4RHGA 2OOQA 5KA2A 1I57A 3RGOA 1Q6PA 2HY3A 4PYHA 4QAPA 4GWFA 3V0EA 5I6VA 2HCMA 2VEVA 2B4SA 1EENA 3GXGA 1A5YA 4PVGA 4J51A 2ZMMA 3S3EA 2B4UA 4WOHA 2PI7A 3MOZA 2QCJA 5BZZA 2I1YA 2J16A 4GFUA 1LQFA 3EMUA 1YTNA 4HRFA 1PA9A 1PA1A 3M4UA 2J16B 5IBMA 1QXKA 1GFYA 1OHCA 2G6ZA 3MMJA 2I6OA 2NV5A 2VEWA 2I3UA 5KAAA 4OHEA 3ZV2A 1G1GA 3ZMPA 1KAKA 2I6JA 2F6ZA 4ZI4A 4D3QA 1YZ4A 2QCTA 2CMAA 3D44A 2M3VA 2I6IA 2Q05A 3F9BA 1J4XA 4RH9A 3H2XA 2Y96A 2QEPA 2PA5A 3N0AA 4GE6A 2C46A 2IMGA 2H02A 1C88A 3RGQA 4QAHA 2I6MA 1NWLA 3QCCA 1SUGA 1T48A 2H4VA 4WU3A 1PTYA 3S3KA 2FJMA 4HJPA 2NLKA 1MKPA 3RZ2A 4ZRTA 4RI5A 3U96A 3RO1A 4GFVA 1G1FA 1Q6SA 2A3KA 2CNFA 2CM3A 2Q47A 4GS0A 4RKKA 1YTWA 3O4SA 1C85A 2QDPA 1QZ0A 1RXDA 1V3AA 4NNDA 4Y2EA 3QCDA 1U26A 4NX8A
chains in the Genus database with same CATH superfamily
3CM3A 3QCGA 4HJQA 5A5FA 3D1OA 1NL9A 4DGXA 2PT0A 4R0SA 4ICZA 3O4TA 2I42A 2P6XA 4OHHA 5KABA 4QBWA 2I3RA 2B07A 4NWFA 2F70A 4GE5A 1NZ7A 1PYNA 2AM2A 2I4HA 2H03A 1OEOX 2AHSA 4KYRA 3ZMQA 1YN9A 1ZZWA 4R0TA 3QCHA 1WAXA 2VTDA 1OEVA 2H4GA 2PQ5A 3AWEA 1G4US 2NTAA 4Z6BA 3MOWA 1L8GA 5K9VA 5K23A 2NT2A 5HDEA 4H34A 2B3OA 3PYZA 5KA0A 1T4JA 2A8BA 4MBBA 3B7OA 3D9CA 4BPCA 3S4OA 4QUNA 3QCNA 2JFGA 5KA8A 1PTVA 3ZM5A 3HN7A 2X5OA 1XBOA 4IKCA 2QBSA 3BRHA 3UAGA 3S3FA 3BLUA 2QDCA 2I6PA 4Y14A 3ZL8A 3EAXA 1JBWA 4R30A 1C84A 3QCLA 2CNHA 4B04A 2WGPA 1U25A 3LJ8A 4DGPA 2Y66A 1JF7A 2OUDA 2CM8A 2VEXA 2OZ5A 2PSZA 1FPZA 1ZCLA 2NT7A 5BZXA 3V0IA 2XPCA 4WTYA 2FH7A 3EZZA 1Q1MA 3ZM1A 1YPTA 2J17A 5BX1A 4TVVA 1ZC0A 3I80A 4I8NA 2CNEA 2P4DA 2HNQA 3ZM0A 2B4OA 1FGSA 1WCHA 4ERCA 2F6YA 5AWXA 1GG4A 1JLNA 1GQYA 2BGEA 2UUPA 3F81A 4OHLA 2CJZA 2CM7A 4C13A 1Q6TA 1YTSA 1LARA 3QKPA 3NMEA 4HV4A 1FPRA 1BZCA 1XXVA 5KA1A 3SR9A 1VHRA 4JMKA 2HXPA 2ZN7A 4OHDA 3PS5A 2HC1A 3S3HA 1NWEA 2CM2A 5KA9A 3V0HA 3D1HA 1OHEA 1UAGA 1O5ZA 3AWGA 4AZ1A 1BZHA 5EHRA 4GRZA 4NWGA 2PBNA 2B4PA 4QBEA 2BIJA 2HVLA 5K25A 4S0GA 1U24A 2QBPA 3D42A 4WU2A 2AZRA 3QCJA 2QDMA 3BLTA 5K22A 1GQQA 2GJTA 4QF5A 4GE2A 1R6HA 3QCKA 1PTTA 1YFOA 1P15A 3QCEA 4YR8B 2F71A 2UUOA 2GCAA 2E0TA 2HC2A 1FQ1A 4JBCA 3ZM2A 2NZ6A 1AAXA 1P3DA 5K24A 1PXHA 2MBCA 1LYVA 1X24A 5GTJA 4QDIA 1BZJA 1ONZA 2SHPA 3BM8A 3QCIA 3I7ZA 1ZCKA 2BGDA 2Y2FA 5LXQB 1XRIA 1YGRA 1RPMA 2F6WA 1WRMA 2CNIA 2JFFA 2QBRA 3A5KA 1EEHA 5MMZB 3LK7A 2F6VA 2GC6A 2BZLA 2HNPA 1Q6MA 4RH5A 1E0DA 1OEUA 2QBQA 3V0DA 5KA7A 2B49A 4NYHA 2GWOA 5M43A 3D1QA 1XXPA 4BJOA 5KA4A 2H04A 2I4EA 3V0FA 5KA3A 2I5XA 1G1HA 4RI4A 2F00A 4GRYA 2GP0A 1OEMX 2OC3A 3O3LA 2F6FA 1W7KA 1G7GA 2FJNA 2F46A 4C12A 2WJPA 5K9WA 5KACA 3F9AA 3V0JA 4KI9A 1OESA 1PTUA 4YAAA 3I36A 1Q6JA 4D3RA 4H1OA 2VTEA 3QCMA 1C83A 1C87A 3GXHA 1GWZA 1I9TA 3S4EA 1G7FA 1Q6NA 5IBSA 2RF6A 5BUGA 2I75A 2JJDA 3QCFA 1OETA 2CFVA 3F99A 2I4GA 3O4UA 2CMBA 1YGUA 3ZM3A 1I9SA 1T49A 2BV5A 3O5XA 3EU0A 2DXPA 2G59A 4BUCA 1NO6A 2VEYA 1EEOA 2GCBA 1OHDA 1XM2A 1ECVA 3CWEA 4KYQA 3SMEA 2ESBA 4ZIYA 3N2AA 1KAVA 1G4WR 1D5RA 3EB1A 3OMHA 3QCBA 2C7SA 1JBVA 5KADA 3F41A 3A5JA 2CNGA 1PH0A 1NNYA 2HB1A 5A5EA 2R0BA 3ZM6A 2GC5A 4CVMA 2VORA 4JNBA 2F6TA 5EHPA 1YWFA 1M3GA 2H4KA 2YDUA 2VEUA 4OHIA 2Y1OA 3AWFA 1W78A 2JFHA 4RDDA 4QUMA 3QCZA 1ONYA 3OLRA 4D3PA 2AM1A 2CMCA 3QKQA 5J8RA 4JMJA 3V0GA 1L8KA 1C86A 4ZN5A 4RHGA 2OOQA 1P31A 5KA2A 1I57A 3RGOA 1Q6PA 2HY3A 3MVNA 4PYHA 4QAPA 4GWFA 3V0EA 5I6VA 2HCMA 2XJAA 2VEVA 2B4SA 1EENA 3GXGA 1A5YA 4PVGA 4J51A 2ZMMA 3S3EA 2B4UA 4WOHA 2PI7A 3MOZA 2VOSA 2QCJA 5BZZA 2I1YA 2J16A 4GFUA 1LQFA 3EMUA 1YTNA 3NRSA 4HRFA 1PA9A 1PA1A 3M4UA 2J16B 5IBMA 1QXKA 1GFYA 1OHCA 2G6ZA 3MMJA 2I6OA 2NV5A 2VEWA 2I3UA 4CVLA 5KAAA 4OHEA 3ZV2A 1G1GA 4CVKA 3ZMPA 1KAKA 2I6JA 2F6ZA 4ZI4A 4D3QA 1YZ4A 1E8CA 2QCTA 2CMAA 3D44A 2M3VA 2I6IA 2Q05A 3F9BA 1J4XA 4RH9A 2Y67A 3H2XA 2Y96A 2QEPA 2PA5A 3N0AA 4GE6A 2C46A 2IMGA 2H02A 4UAGA 1C88A 3RGQA 4QAHA 2I6MA 1NWLA 3QCCA 1SUGA 1T48A 2H4VA 4WU3A 1PTYA 3S3KA 2FJMA 4HJPA 2NLKA 1MKPA 2Y68A 3RZ2A 4ZRTA 4RI5A 3U96A 4BUBA 3RO1A 4GFVA 1G1FA 1Q6SA 2A3KA 2CNFA 2CM3A 2Q47A 4GS0A 4RKKA 1YTWA 3O4SA 1C85A 2UAGA 2QDPA 1QZ0A 1RXDA 1V3AA 1J6UA 2WTZA 4NNDA 4Y2EA 3QCDA 1U26A 4NX8A
chains in the Genus database with same CATH topology
3CM3A 3QCGA 4HJQA 3D1OA 1NL9A 4DGXA 2PT0A 4R0SA 4ICZA 3O4TA 2I42A 2P6XA 4OHHA 5KABA 4QBWA 2I3RA 2B07A 4NWFA 2F70A 4GE5A 1NZ7A 1PYNA 2I4HA 2H03A 1OEOX 2AHSA 4KYRA 3ZMQA 1YN9A 1ZZWA 4R0TA 3QCHA 1WAXA 1OEVA 2H4GA 2PQ5A 3AWEA 1G4US 2NTAA 4Z6BA 3MOWA 1L8GA 5K9VA 5K23A 2NT2A 5HDEA 4H34A 2B3OA 5KA0A 1T4JA 2A8BA 4MBBA 3B7OA 3D9CA 4BPCA 3S4OA 4QUNA 3QCNA 5KA8A 1PTVA 1XBOA 4IKCA 2QBSA 3BRHA 3S3FA 3BLUA 2QDCA 2I6PA 4Y14A 3EAXA 4R30A 1C84A 3QCLA 2CNHA 4B04A 2WGPA 1U25A 3LJ8A 4DGPA 1JF7A 2OUDA 2CM8A 2VEXA 2OZ5A 2PSZA 1FPZA 1ZCLA 2NT7A 5BZXA 3V0IA 4WTYA 2FH7A 3EZZA 1Q1MA 3ZM1A 1YPTA 2J17A 5BX1A 4TVVA 1ZC0A 3I80A 4I8NA 2CNEA 2P4DA 2HNQA 3ZM0A 2B4OA 1WCHA 4ERCA 2F6YA 5AWXA 1JLNA 2BGEA 3F81A 4OHLA 2CJZA 2CM7A 1Q6TA 1YTSA 1LARA 3QKPA 3NMEA 1FPRA 1BZCA 1XXVA 5KA1A 3SR9A 1VHRA 4JMKA 2HXPA 2ZN7A 4OHDA 3PS5A 2HC1A 3S3HA 1NWEA 2CM2A 5KA9A 3V0HA 3D1HA 1OHEA 3AWGA 4AZ1A 1BZHA 5EHRA 4GRZA 4NWGA 2PBNA 2B4PA 4QBEA 2BIJA 2HVLA 5K25A 4S0GA 1U24A 2QBPA 3D42A 4WU2A 2AZRA 3QCJA 2QDMA 3BLTA 5K22A 2GJTA 4GE2A 1R6HA 3QCKA 1PTTA 1YFOA 1P15A 3QCEA 4YR8B 2F71A 2E0TA 2HC2A 1FQ1A 4JBCA 3ZM2A 2NZ6A 1AAXA 5K24A 1PXHA 2MBCA 1LYVA 1X24A 5GTJA 1BZJA 1ONZA 2SHPA 3BM8A 3QCIA 3I7ZA 1ZCKA 2BGDA 2Y2FA 5LXQB 1XRIA 1YGRA 1RPMA 2F6WA 1WRMA 2CNIA 2QBRA 3A5KA 5MMZB 2F6VA 2BZLA 2HNPA 1Q6MA 4RH5A 1OEUA 2QBQA 3V0DA 5KA7A 2B49A 4NYHA 2GWOA 5M43A 3D1QA 1XXPA 4BJOA 5KA4A 2H04A 2I4EA 3V0FA 5KA3A 2I5XA 1G1HA 4RI4A 4GRYA 2GP0A 1OEMX 2OC3A 3O3LA 2F6FA 2FJNA 1G7GA 2F46A 5K9WA 5KACA 3F9AA 3V0JA 4KI9A 1OESA 1PTUA 4YAAA 3I36A 1Q6JA 4D3RA 4H1OA 3QCMA 1C83A 1C87A 3GXHA 1GWZA 1I9TA 3S4EA 1Q6NA 1G7FA 5IBSA 2RF6A 5BUGA 2I75A 2JJDA 3QCFA 1OETA 2CFVA 3F99A 2I4GA 3O4UA 2CMBA 1YGUA 3ZM3A 1I9SA 1T49A 2BV5A 3O5XA 3EU0A 2DXPA 2G59A 1NO6A 2VEYA 1EEOA 1OHDA 1XM2A 1ECVA 3CWEA 4KYQA 3SMEA 2ESBA 1KAVA 1G4WR 1D5RA 3EB1A 3OMHA 3QCBA 2C7SA 5KADA 3F41A 3A5JA 2CNGA 1PH0A 1NNYA 2HB1A 2R0BA 4JNBA 2F6TA 5EHPA 1YWFA 1M3GA 2H4KA 2YDUA 2VEUA 4OHIA 3AWFA 4RDDA 4QUMA 1ONYA 3OLRA 4D3PA 2CMCA 3QKQA 5J8RA 4JMJA 3V0GA 1L8KA 1C86A 4ZN5A 4RHGA 2OOQA 5KA2A 1I57A 3RGOA 1Q6PA 2HY3A 4PYHA 4QAPA 4GWFA 3V0EA 5I6VA 2HCMA 2VEVA 2B4SA 1EENA 3GXGA 1A5YA 4PVGA 4J51A 2ZMMA 3S3EA 2B4UA 4WOHA 2PI7A 3MOZA 2QCJA 5BZZA 2I1YA 2J16A 4GFUA 1LQFA 3EMUA 1YTNA 4HRFA 1PA9A 1PA1A 3M4UA 2J16B 5IBMA 1QXKA 1GFYA 1OHCA 2G6ZA 3MMJA 2I6OA 2NV5A 2VEWA 2I3UA 5KAAA 4OHEA 3ZV2A 1G1GA 3ZMPA 1KAKA 2I6JA 2F6ZA 4ZI4A 4D3QA 1YZ4A 2QCTA 2CMAA 3D44A 2M3VA 2I6IA 2Q05A 3F9BA 1J4XA 4RH9A 3H2XA 2Y96A 2QEPA 2PA5A 3N0AA 4GE6A 2C46A 2IMGA 2H02A 1C88A 3RGQA 4QAHA 2I6MA 1NWLA 3QCCA 1SUGA 1T48A 2H4VA 4WU3A 1PTYA 3S3KA 2FJMA 4HJPA 2NLKA 1MKPA 3RZ2A 4ZRTA 4RI5A 3U96A 3RO1A 4GFVA 1G1FA 1Q6SA 2A3KA 2CNFA 2CM3A 2Q47A 4GS0A 4RKKA 1YTWA 3O4SA 1C85A 2QDPA 1QZ0A 1RXDA 1V3AA 4NNDA 4Y2EA 3QCDA 1U26A 4NX8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CM3 A;  3QCG A;  4HJQ A;  3D1O A;  1NL9 A;  4DGX A;  2PT0 A;  4R0S A;  4ICZ A;  3O4T A;  2I42 A;  2P6X A;  4OHH A;  5KAB A;  4QBW A;  2I3R A;  2B07 A;  4NWF A;  2F70 A;  4GE5 A;  1NZ7 A;  1PYN A;  2I4H A;  2H03 A;  1OEO X;  2AHS A;  4KYR A;  3ZMQ A;  1YN9 A;  1ZZW A;  4R0T A;  3QCH A;  1WAX A;  1OEV A;  2H4G A;  2PQ5 A;  3AWE A;  1G4U S;  2NTA A;  4Z6B A;  3MOW A;  1L8G A;  5K9V A;  5K23 A;  2NT2 A;  5HDE A;  4H34 A;  2B3O A;  5KA0 A;  1T4J A;  2A8B A;  4MBB A;  3B7O A;  3D9C A;  4BPC A;  3S4O A;  4QUN A;  3QCN A;  5KA8 A;  1PTV A;  1XBO A;  4IKC A;  2QBS A;  3BRH A;  3S3F A;  3BLU A;  2QDC A;  2I6P A;  4Y14 A;  3EAX A;  4R30 A;  1C84 A;  3QCL A;  2CNH A;  4B04 A;  2WGP A;  1U25 A;  3LJ8 A;  4DGP A;  1JF7 A;  2OUD A;  2CM8 A;  2VEX A;  2OZ5 A;  2PSZ A;  1FPZ A;  1ZCL A;  2NT7 A;  5BZX A;  3V0I A;  4WTY A;  2FH7 A;  3EZZ A;  1Q1M A;  3ZM1 A;  1YPT A;  2J17 A;  5BX1 A;  4TVV A;  1ZC0 A;  3I80 A;  4I8N A;  2CNE A;  2P4D A;  2HNQ A;  3ZM0 A;  2B4O A;  1WCH A;  4ERC A;  2F6Y A;  5AWX A;  1JLN A;  2BGE A;  3F81 A;  4OHL A;  2CJZ A;  2CM7 A;  1Q6T A;  1YTS A;  1LAR A;  3QKP A;  3NME A;  1FPR A;  1BZC A;  1XXV A;  5KA1 A;  3SR9 A;  1VHR A;  4JMK A;  2HXP A;  2ZN7 A;  4OHD A;  3PS5 A;  2HC1 A;  3S3H A;  1NWE A;  2CM2 A;  5KA9 A;  3V0H A;  3D1H A;  1OHE A;  3AWG A;  4AZ1 A;  1BZH A;  5EHR A;  4GRZ A;  4NWG A;  2PBN A;  2B4P A;  4QBE A;  2BIJ A;  2HVL A;  5K25 A;  4S0G A;  1U24 A;  2QBP A;  3D42 A;  4WU2 A;  2AZR A;  3QCJ A;  2QDM A;  3BLT A;  5K22 A;  2GJT A;  4GE2 A;  1R6H A;  3QCK A;  1PTT A;  1YFO A;  1P15 A;  3QCE A;  4YR8 B;  2F71 A;  2E0T A;  2HC2 A;  1FQ1 A;  4JBC A;  3ZM2 A;  2NZ6 A;  1AAX A;  5K24 A;  1PXH A;  2MBC A;  1LYV A;  1X24 A;  5GTJ A;  1BZJ A;  1ONZ A;  2SHP A;  3BM8 A;  3QCI A;  3I7Z A;  1ZCK A;  2BGD A;  2Y2F A;  5LXQ B;  1XRI A;  1YGR A;  1RPM A;  2F6W A;  1WRM A;  2CNI A;  2QBR A;  3A5K A;  5MMZ B;  2F6V A;  2BZL A;  2HNP A;  1Q6M A;  4RH5 A;  1OEU A;  2QBQ A;  3V0D A;  5KA7 A;  2B49 A;  4NYH A;  2GWO A;  5M43 A;  3D1Q A;  1XXP A;  4BJO A;  5KA4 A;  2H04 A;  2I4E A;  3V0F A;  5KA3 A;  2I5X A;  1G1H A;  4RI4 A;  4GRY A;  2GP0 A;  1OEM X;  2OC3 A;  3O3L A;  2F6F A;  2FJN A;  1G7G A;  2F46 A;  5K9W A;  5KAC A;  3F9A A;  3V0J A;  4KI9 A;  1OES A;  1PTU A;  4YAA A;  3I36 A;  1Q6J A;  4D3R A;  4H1O A;  3QCM A;  1C83 A;  1C87 A;  3GXH A;  1GWZ A;  1I9T A;  3S4E A;  1Q6N A;  1G7F A;  5IBS A;  2RF6 A;  5BUG A;  2I75 A;  2JJD A;  3QCF A;  1OET A;  2CFV A;  3F99 A;  2I4G A;  3O4U A;  2CMB A;  1YGU A;  3ZM3 A;  1I9S A;  1T49 A;  2BV5 A;  3O5X A;  3EU0 A;  2DXP A;  2G59 A;  1NO6 A;  2VEY A;  1EEO A;  1OHD A;  1XM2 A;  1ECV A;  3CWE A;  4KYQ A;  3SME A;  2ESB A;  1KAV A;  1G4W R;  1D5R A;  3EB1 A;  3OMH A;  3QCB A;  2C7S A;  5KAD A;  3F41 A;  3A5J A;  2CNG A;  1PH0 A;  1NNY A;  2HB1 A;  2R0B A;  4JNB A;  2F6T A;  5EHP A;  1YWF A;  1M3G A;  2H4K A;  2YDU A;  2VEU A;  4OHI A;  3AWF A;  4RDD A;  4QUM A;  1ONY A;  3OLR A;  4D3P A;  2CMC A;  3QKQ A;  5J8R A;  4JMJ A;  3V0G A;  1L8K A;  1C86 A;  4ZN5 A;  4RHG A;  2OOQ A;  5KA2 A;  1I57 A;  3RGO A;  1Q6P A;  2HY3 A;  4PYH A;  4QAP A;  4GWF A;  3V0E A;  5I6V A;  2HCM A;  2VEV A;  2B4S A;  1EEN A;  3GXG A;  1A5Y A;  4PVG A;  4J51 A;  2ZMM A;  3S3E A;  2B4U A;  4WOH A;  2PI7 A;  3MOZ A;  2QCJ A;  5BZZ A;  2I1Y A;  2J16 A;  4GFU A;  1LQF A;  3EMU A;  1YTN A;  4HRF A;  1PA9 A;  1PA1 A;  3M4U A;  2J16 B;  5IBM A;  1QXK A;  1GFY A;  1OHC A;  2G6Z A;  3MMJ A;  2I6O A;  2NV5 A;  2VEW A;  2I3U A;  5KAA A;  4OHE A;  3ZV2 A;  1G1G A;  3ZMP A;  1KAK A;  2I6J A;  2F6Z A;  4ZI4 A;  4D3Q A;  1YZ4 A;  2QCT A;  2CMA A;  3D44 A;  2M3V A;  2I6I A;  2Q05 A;  3F9B A;  1J4X A;  4RH9 A;  3H2X A;  2Y96 A;  2QEP A;  2PA5 A;  3N0A A;  4GE6 A;  2C46 A;  2IMG A;  2H02 A;  1C88 A;  3RGQ A;  4QAH A;  2I6M A;  1NWL A;  3QCC A;  1SUG A;  1T48 A;  2H4V A;  4WU3 A;  1PTY A;  3S3K A;  2FJM A;  4HJP A;  2NLK A;  1MKP A;  3RZ2 A;  4ZRT A;  4RI5 A;  3U96 A;  3RO1 A;  4GFV A;  1G1F A;  1Q6S A;  2A3K A;  2CNF A;  2CM3 A;  2Q47 A;  4GS0 A;  4RKK A;  1YTW A;  3O4S A;  1C85 A;  2QDP A;  1QZ0 A;  1RXD A;  1V3A A;  4NND A;  4Y2E A;  3QCD A;  1U26 A;  4NX8 A; 
#chains in the Genus database with same CATH topology
 3CM3 A;  3QCG A;  4HJQ A;  5A5F A;  3D1O A;  1NL9 A;  4DGX A;  2PT0 A;  4R0S A;  4ICZ A;  3O4T A;  2I42 A;  2P6X A;  4OHH A;  5KAB A;  4QBW A;  2I3R A;  2B07 A;  4NWF A;  2F70 A;  4GE5 A;  1NZ7 A;  1PYN A;  2AM2 A;  2I4H A;  2H03 A;  1OEO X;  2AHS A;  4KYR A;  3ZMQ A;  1YN9 A;  1ZZW A;  4R0T A;  3QCH A;  1WAX A;  2VTD A;  1OEV A;  2H4G A;  2PQ5 A;  3AWE A;  1G4U S;  2NTA A;  4Z6B A;  3MOW A;  1L8G A;  5K9V A;  5K23 A;  2NT2 A;  5HDE A;  4H34 A;  2B3O A;  3PYZ A;  5KA0 A;  1T4J A;  2A8B A;  4MBB A;  3B7O A;  3D9C A;  4BPC A;  3S4O A;  4QUN A;  3QCN A;  2JFG A;  5KA8 A;  1PTV A;  3ZM5 A;  3HN7 A;  2X5O A;  1XBO A;  4IKC A;  2QBS A;  3BRH A;  3UAG A;  3S3F A;  3BLU A;  2QDC A;  2I6P A;  4Y14 A;  3ZL8 A;  3EAX A;  1JBW A;  4R30 A;  1C84 A;  3QCL A;  2CNH A;  4B04 A;  2WGP A;  1U25 A;  3LJ8 A;  4DGP A;  2Y66 A;  1JF7 A;  2OUD A;  2CM8 A;  2VEX A;  2OZ5 A;  2PSZ A;  1FPZ A;  1ZCL A;  2NT7 A;  5BZX A;  3V0I A;  2XPC A;  4WTY A;  2FH7 A;  3EZZ A;  1Q1M A;  3ZM1 A;  1YPT A;  2J17 A;  5BX1 A;  4TVV A;  1ZC0 A;  3I80 A;  4I8N A;  2CNE A;  2P4D A;  2HNQ A;  3ZM0 A;  2B4O A;  1FGS A;  1WCH A;  4ERC A;  2F6Y A;  5AWX A;  1GG4 A;  1JLN A;  1GQY A;  2BGE A;  2UUP A;  3F81 A;  4OHL A;  2CJZ A;  2CM7 A;  4C13 A;  1Q6T A;  1YTS A;  1LAR A;  3QKP A;  3NME A;  4HV4 A;  1FPR A;  1BZC A;  1XXV A;  5KA1 A;  3SR9 A;  1VHR A;  4JMK A;  2HXP A;  2ZN7 A;  4OHD A;  3PS5 A;  2HC1 A;  3S3H A;  1NWE A;  2CM2 A;  5KA9 A;  3V0H A;  3D1H A;  1OHE A;  1UAG A;  1O5Z A;  3AWG A;  4AZ1 A;  1BZH A;  5EHR A;  4GRZ A;  4NWG A;  2PBN A;  2B4P A;  4QBE A;  2BIJ A;  2HVL A;  5K25 A;  4S0G A;  1U24 A;  2QBP A;  3D42 A;  4WU2 A;  2AZR A;  3QCJ A;  2QDM A;  3BLT A;  5K22 A;  1GQQ A;  2GJT A;  4QF5 A;  4GE2 A;  1R6H A;  3QCK A;  1PTT A;  1YFO A;  1P15 A;  3QCE A;  4YR8 B;  2F71 A;  2UUO A;  2GCA A;  2E0T A;  2HC2 A;  1FQ1 A;  4JBC A;  3ZM2 A;  2NZ6 A;  1AAX A;  1P3D A;  5K24 A;  1PXH A;  2MBC A;  1LYV A;  1X24 A;  5GTJ A;  4QDI A;  1BZJ A;  1ONZ A;  2SHP A;  3BM8 A;  3QCI A;  3I7Z A;  1ZCK A;  2BGD A;  2Y2F A;  5LXQ B;  1XRI A;  1YGR A;  1RPM A;  2F6W A;  1WRM A;  2CNI A;  2JFF A;  2QBR A;  3A5K A;  1EEH A;  5MMZ B;  3LK7 A;  2F6V A;  2GC6 A;  2BZL A;  2HNP A;  1Q6M A;  4RH5 A;  1E0D A;  1OEU A;  2QBQ A;  3V0D A;  5KA7 A;  2B49 A;  4NYH A;  2GWO A;  5M43 A;  3D1Q A;  1XXP A;  4BJO A;  5KA4 A;  2H04 A;  2I4E A;  3V0F A;  5KA3 A;  2I5X A;  1G1H A;  4RI4 A;  2F00 A;  4GRY A;  2GP0 A;  1OEM X;  2OC3 A;  3O3L A;  2F6F A;  1W7K A;  1G7G A;  2FJN A;  2F46 A;  4C12 A;  2WJP A;  5K9W A;  5KAC A;  3F9A A;  3V0J A;  4KI9 A;  1OES A;  1PTU A;  4YAA A;  3I36 A;  1Q6J A;  4D3R A;  4H1O A;  2VTE A;  3QCM A;  1C83 A;  1C87 A;  3GXH A;  1GWZ A;  1I9T A;  3S4E A;  1G7F A;  1Q6N A;  5IBS A;  2RF6 A;  5BUG A;  2I75 A;  2JJD A;  3QCF A;  1OET A;  2CFV A;  3F99 A;  2I4G A;  3O4U A;  2CMB A;  1YGU A;  3ZM3 A;  1I9S A;  1T49 A;  2BV5 A;  3O5X A;  3EU0 A;  2DXP A;  2G59 A;  4BUC A;  1NO6 A;  2VEY A;  1EEO A;  2GCB A;  1OHD A;  1XM2 A;  1ECV A;  3CWE A;  4KYQ A;  3SME A;  2ESB A;  4ZIY A;  3N2A A;  1KAV A;  1G4W R;  1D5R A;  3EB1 A;  3OMH A;  3QCB A;  2C7S A;  1JBV A;  5KAD A;  3F41 A;  3A5J A;  2CNG A;  1PH0 A;  1NNY A;  2HB1 A;  5A5E A;  2R0B A;  3ZM6 A;  2GC5 A;  4CVM A;  2VOR A;  4JNB A;  2F6T A;  5EHP A;  1YWF A;  1M3G A;  2H4K A;  2YDU A;  2VEU A;  4OHI A;  2Y1O A;  3AWF A;  1W78 A;  2JFH A;  4RDD A;  4QUM A;  3QCZ A;  1ONY A;  3OLR A;  4D3P A;  2AM1 A;  2CMC A;  3QKQ A;  5J8R A;  4JMJ A;  3V0G A;  1L8K A;  1C86 A;  4ZN5 A;  4RHG A;  2OOQ A;  1P31 A;  5KA2 A;  1I57 A;  3RGO A;  1Q6P A;  2HY3 A;  3MVN A;  4PYH A;  4QAP A;  4GWF A;  3V0E A;  5I6V A;  2HCM A;  2XJA A;  2VEV A;  2B4S A;  1EEN A;  3GXG A;  1A5Y A;  4PVG A;  4J51 A;  2ZMM A;  3S3E A;  2B4U A;  4WOH A;  2PI7 A;  3MOZ A;  2VOS A;  2QCJ A;  5BZZ A;  2I1Y A;  2J16 A;  4GFU A;  1LQF A;  3EMU A;  1YTN A;  3NRS A;  4HRF A;  1PA9 A;  1PA1 A;  3M4U A;  2J16 B;  5IBM A;  1QXK A;  1GFY A;  1OHC A;  2G6Z A;  3MMJ A;  2I6O A;  2NV5 A;  2VEW A;  2I3U A;  4CVL A;  5KAA A;  4OHE A;  3ZV2 A;  1G1G A;  4CVK A;  3ZMP A;  1KAK A;  2I6J A;  2F6Z A;  4ZI4 A;  4D3Q A;  1YZ4 A;  1E8C A;  2QCT A;  2CMA A;  3D44 A;  2M3V A;  2I6I A;  2Q05 A;  3F9B A;  1J4X A;  4RH9 A;  2Y67 A;  3H2X A;  2Y96 A;  2QEP A;  2PA5 A;  3N0A A;  4GE6 A;  2C46 A;  2IMG A;  2H02 A;  4UAG A;  1C88 A;  3RGQ A;  4QAH A;  2I6M A;  1NWL A;  3QCC A;  1SUG A;  1T48 A;  2H4V A;  4WU3 A;  1PTY A;  3S3K A;  2FJM A;  4HJP A;  2NLK A;  1MKP A;  2Y68 A;  3RZ2 A;  4ZRT A;  4RI5 A;  3U96 A;  4BUB A;  3RO1 A;  4GFV A;  1G1F A;  1Q6S A;  2A3K A;  2CNF A;  2CM3 A;  2Q47 A;  4GS0 A;  4RKK A;  1YTW A;  3O4S A;  1C85 A;  2UAG A;  2QDP A;  1QZ0 A;  1RXD A;  1V3A A;  1J6U A;  2WTZ A;  4NND A;  4Y2E A;  3QCD A;  1U26 A;  4NX8 A; 
#chains in the Genus database with same CATH homology
 3CM3 A;  3QCG A;  4HJQ A;  3D1O A;  1NL9 A;  4DGX A;  2PT0 A;  4R0S A;  4ICZ A;  3O4T A;  2I42 A;  2P6X A;  4OHH A;  5KAB A;  4QBW A;  2I3R A;  2B07 A;  4NWF A;  2F70 A;  4GE5 A;  1NZ7 A;  1PYN A;  2I4H A;  2H03 A;  1OEO X;  2AHS A;  4KYR A;  3ZMQ A;  1YN9 A;  1ZZW A;  4R0T A;  3QCH A;  1WAX A;  1OEV A;  2H4G A;  2PQ5 A;  3AWE A;  1G4U S;  2NTA A;  4Z6B A;  3MOW A;  1L8G A;  5K9V A;  5K23 A;  2NT2 A;  5HDE A;  4H34 A;  2B3O A;  5KA0 A;  1T4J A;  2A8B A;  4MBB A;  3B7O A;  3D9C A;  4BPC A;  3S4O A;  4QUN A;  3QCN A;  5KA8 A;  1PTV A;  1XBO A;  4IKC A;  2QBS A;  3BRH A;  3S3F A;  3BLU A;  2QDC A;  2I6P A;  4Y14 A;  3EAX A;  4R30 A;  1C84 A;  3QCL A;  2CNH A;  4B04 A;  2WGP A;  1U25 A;  3LJ8 A;  4DGP A;  1JF7 A;  2OUD A;  2CM8 A;  2VEX A;  2OZ5 A;  2PSZ A;  1FPZ A;  1ZCL A;  2NT7 A;  5BZX A;  3V0I A;  4WTY A;  2FH7 A;  3EZZ A;  1Q1M A;  3ZM1 A;  1YPT A;  2J17 A;  5BX1 A;  4TVV A;  1ZC0 A;  3I80 A;  4I8N A;  2CNE A;  2P4D A;  2HNQ A;  3ZM0 A;  2B4O A;  1WCH A;  4ERC A;  2F6Y A;  5AWX A;  1JLN A;  2BGE A;  3F81 A;  4OHL A;  2CJZ A;  2CM7 A;  1Q6T A;  1YTS A;  1LAR A;  3QKP A;  3NME A;  1FPR A;  1BZC A;  1XXV A;  5KA1 A;  3SR9 A;  1VHR A;  4JMK A;  2HXP A;  2ZN7 A;  4OHD A;  3PS5 A;  2HC1 A;  3S3H A;  1NWE A;  2CM2 A;  5KA9 A;  3V0H A;  3D1H A;  1OHE A;  3AWG A;  4AZ1 A;  1BZH A;  5EHR A;  4GRZ A;  4NWG A;  2PBN A;  2B4P A;  4QBE A;  2BIJ A;  2HVL A;  5K25 A;  4S0G A;  1U24 A;  2QBP A;  3D42 A;  4WU2 A;  2AZR A;  3QCJ A;  2QDM A;  3BLT A;  5K22 A;  2GJT A;  4GE2 A;  1R6H A;  3QCK A;  1PTT A;  1YFO A;  1P15 A;  3QCE A;  4YR8 B;  2F71 A;  2E0T A;  2HC2 A;  1FQ1 A;  4JBC A;  3ZM2 A;  2NZ6 A;  1AAX A;  5K24 A;  1PXH A;  2MBC A;  1LYV A;  1X24 A;  5GTJ A;  1BZJ A;  1ONZ A;  2SHP A;  3BM8 A;  3QCI A;  3I7Z A;  1ZCK A;  2BGD A;  2Y2F A;  5LXQ B;  1XRI A;  1YGR A;  1RPM A;  2F6W A;  1WRM A;  2CNI A;  2QBR A;  3A5K A;  5MMZ B;  2F6V A;  2BZL A;  2HNP A;  1Q6M A;  4RH5 A;  1OEU A;  2QBQ A;  3V0D A;  5KA7 A;  2B49 A;  4NYH A;  2GWO A;  5M43 A;  3D1Q A;  1XXP A;  4BJO A;  5KA4 A;  2H04 A;  2I4E A;  3V0F A;  5KA3 A;  2I5X A;  1G1H A;  4RI4 A;  4GRY A;  2GP0 A;  1OEM X;  2OC3 A;  3O3L A;  2F6F A;  2FJN A;  1G7G A;  2F46 A;  5K9W A;  5KAC A;  3F9A A;  3V0J A;  4KI9 A;  1OES A;  1PTU A;  4YAA A;  3I36 A;  1Q6J A;  4D3R A;  4H1O A;  3QCM A;  1C83 A;  1C87 A;  3GXH A;  1GWZ A;  1I9T A;  3S4E A;  1Q6N A;  1G7F A;  5IBS A;  2RF6 A;  5BUG A;  2I75 A;  2JJD A;  3QCF A;  1OET A;  2CFV A;  3F99 A;  2I4G A;  3O4U A;  2CMB A;  1YGU A;  3ZM3 A;  1I9S A;  1T49 A;  2BV5 A;  3O5X A;  3EU0 A;  2DXP A;  2G59 A;  1NO6 A;  2VEY A;  1EEO A;  1OHD A;  1XM2 A;  1ECV A;  3CWE A;  4KYQ A;  3SME A;  2ESB A;  1KAV A;  1G4W R;  1D5R A;  3EB1 A;  3OMH A;  3QCB A;  2C7S A;  5KAD A;  3F41 A;  3A5J A;  2CNG A;  1PH0 A;  1NNY A;  2HB1 A;  2R0B A;  4JNB A;  2F6T A;  5EHP A;  1YWF A;  1M3G A;  2H4K A;  2YDU A;  2VEU A;  4OHI A;  3AWF A;  4RDD A;  4QUM A;  1ONY A;  3OLR A;  4D3P A;  2CMC A;  3QKQ A;  5J8R A;  4JMJ A;  3V0G A;  1L8K A;  1C86 A;  4ZN5 A;  4RHG A;  2OOQ A;  5KA2 A;  1I57 A;  3RGO A;  1Q6P A;  2HY3 A;  4PYH A;  4QAP A;  4GWF A;  3V0E A;  5I6V A;  2HCM A;  2VEV A;  2B4S A;  1EEN A;  3GXG A;  1A5Y A;  4PVG A;  4J51 A;  2ZMM A;  3S3E A;  2B4U A;  4WOH A;  2PI7 A;  3MOZ A;  2QCJ A;  5BZZ A;  2I1Y A;  2J16 A;  4GFU A;  1LQF A;  3EMU A;  1YTN A;  4HRF A;  1PA9 A;  1PA1 A;  3M4U A;  2J16 B;  5IBM A;  1QXK A;  1GFY A;  1OHC A;  2G6Z A;  3MMJ A;  2I6O A;  2NV5 A;  2VEW A;  2I3U A;  5KAA A;  4OHE A;  3ZV2 A;  1G1G A;  3ZMP A;  1KAK A;  2I6J A;  2F6Z A;  4ZI4 A;  4D3Q A;  1YZ4 A;  2QCT A;  2CMA A;  3D44 A;  2M3V A;  2I6I A;  2Q05 A;  3F9B A;  1J4X A;  4RH9 A;  3H2X A;  2Y96 A;  2QEP A;  2PA5 A;  3N0A A;  4GE6 A;  2C46 A;  2IMG A;  2H02 A;  1C88 A;  3RGQ A;  4QAH A;  2I6M A;  1NWL A;  3QCC A;  1SUG A;  1T48 A;  2H4V A;  4WU3 A;  1PTY A;  3S3K A;  2FJM A;  4HJP A;  2NLK A;  1MKP A;  3RZ2 A;  4ZRT A;  4RI5 A;  3U96 A;  3RO1 A;  4GFV A;  1G1F A;  1Q6S A;  2A3K A;  2CNF A;  2CM3 A;  2Q47 A;  4GS0 A;  4RKK A;  1YTW A;  3O4S A;  1C85 A;  2QDP A;  1QZ0 A;  1RXD A;  1V3A A;  4NND A;  4Y2E A;  3QCD A;  1U26 A;  4NX8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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