3QLSA

Candida albicans dihydrofolate reductase complexed with nadph and 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp115a)
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
192
structure length
192
Chain Sequence
MLKPNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Candida albicans Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal the Flexibility of Active Site Loop Residues Critical for Ligand Potency and Selectivity.
pubmed doi rcsb
molecule keywords Putative uncharacterized protein CaJ7.0360
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Candida albicans
total genus 56
structure length 192
sequence length 192
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2011-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3qlsA00
3DL6A 1DREA 4P3QA 4M2XA 5HQYA 3QLRA 5EAJA 5HF0X 1JUVA 1MVSA 1DR3A 4QHVA 2FZHA 4KFJA 4PSTA 4M7VA 3F0BX 4ECKA 2BLCA 4Q0DA 3E0BA 1BOZA 4HA7A 3FRAX 4M6KA 4P3RA 4KY4A 3JWMA 1DHJA 1BZFA 3CSEA 5JG0X 3S9UA 5HVEA 3QLXA 1DR6A 4HA9A 3SRSX 2W3BA 4Q0EA 1DR5A 4QJZD 4X5JA 2W3AA 1RX2A 4ELHA 3FL8A 5U26A 4M7UA 1DRBA 4EIZA 3NZAX 4KL9A 3SAIA 3CD2A 7DFRA 4HOGA 2B3ZA 1OHKA 2W3MA 3EEJA 3DL5A 1DG5A 3TQAA 1DIUA 1RF7A 4PTHA 3SGYA 3FY8X 2AZNA 2L28A 1U70A 4KJLA 3RO9A 3M08A 3LG4A 2BLBA 3K2HA 4I1NA 4CD2A 3NZ6X 3FRBX 2OIPA 3NXRA 4Q67A 5CCCA 4XECX 1DYJA 3NZBX 3L3RA 4TU5X 3F0QX 3FYWX 1DISA 3SH2A 8DFRA 4KM0A 3HJ3A 2W3WA 3SQYX 4ELFA 2HQPA 4DFRA 1RX8A 3S7AA 1CZ3A 1RX5A 3CLBA 3NTZA 4GH8A 3K45A 3QL0A 3JSUA 1LY4A 4KNEA 4KYAA 1DLRA 3NZDA 5HSUA 3FRFX 4ELGA 4M6LA 3NXOA 3M09A 3FQVA 4XT7A 2W9GA 1VJ3A 3GHCA 4KM2A 5HF2X 4G8ZX 5U27A 1J3IA 2FZIA 3I3RA 5HI6A 3NXXA 1M78A 4KJKA 4G3MA 1RX3A 1DR1A 2LF1A 3F0XX 4X5IA 5HT5A 3SA2A 2O7PA 1RX1A 1LY3A 5E8QA 2INQA 2QK8A 4KY8A 2D0KA 4KD7A 1MVTA 4KLXA 3GI2A 1TDRA 4H96A 4LAEX 1RA2A 5HVBA 1RX4A 1DYIA 4XT4A 3EEMA 3N0HA 4FGHA 4EJ1A 3TQ8A 1IA1A 4FHBA 3QLYA 2D5NA 3DG8A 3IROA 1RA3A 4DPDA 4H98A 1SEJA 4EILA 2HXVA 3UM8A 3D84X 3EIGA 1KMSA 3IA4A 1DYHA 1J3JA 2FZJA 3UM5A 1YHOA 3ZPGA 3FRDX 3UM6A 3F0SX 4QLGA 1IA3A 3OAFA 1DR2A 5ECCA 1S3WA 3JW5A 3D80A 3QYLA 1DYRA 1DDRA 3EELA 3F91A 3GHVA 4DPHA 3RG9A 3IRMA 4NX7A 3JW3A 1VDRA 2W3VA 1E26A 1RB3A 1DR7A 2JYBA 3TQ9A 3JWFA 3DGAA 4H95A 4P66A 4XT8A 3FQZA 1RH3A 3TD8A 1RA9A 3QLSA 4PSSA 3DRCA 3I8AX 1DHFA 1DG8A 1DR4A 3SR5X 2ZZAA 2DHFA 3IRNA 5HQZA 4PTJA 2W9TA 4X5GA 1S3VA 3QL3A 1RC4A 3KFYA 3NRRA 1RX7A 1RA8A 1RX9A 4QLFA 1RA1A 4IXFX 2CD2A 1HFQA 2GD9A 3IA5A 1RE7A 2BL9A 4LAGX 1DDSA 3CL9A 4G95A 1PD9A 3F0UX 1DLSA 4FGGA 1PDBA 3QLWA 3F0VX 3F8ZA 2HM9A 1JOLA 3DAUA 3FQ0A 4HOEA 3DFRA 5HT4A 1CD2A 3F8YA 4RGCA 5FDAA 3SRQX 1AO8A 4LAHX 3ROAA 3INVA 4KBNA 2XW7A 4P68A 1RG7A 1U72A 3FREX 3VCOA 2CIGA 4PDJA 4LEKX 4QI9A 1IA4A 3FQCA 3OCHA 1AOEA 3QG2A 4IXGX 3QLZA 2C2SA 4XE6X 4HOFA 2ANQA 3JWKA 1ZDRA 3S3VA 4Q6AA 1DRHA 1IA2A 5HPBA 3FQFA 3TQBA 3DATA 3FS6A 3QFXA 2BLAA 1DHIA 3JVXA 3NZCX 4KJJA 1AI9A 1RB2A 2P4GA 4H97A 3JWCA 5ECXA 4EIGA 3ZPCA 6DFRA 5HUIA 4QJCA 1HFRA 3KY8A 3EEKA 3K47A 4KEBA 4NX6A 4DDRA 1S3UA 3KJRA 1KMVA 1LUDA 4XT6A 3JTWA 3NZ9X 2H2QA 2KGKA 4OSGA 1RX6A 4OR7A 4QLEA 4XT5A 1DAJA 2W9SA 2OBCA 4ELEA 4I13A 3FL9A 1S3YA 4X5HA 3IX9A 4ELBA 3HBBA 2G6VA 4XRBA 4M6JA 2ANOA 4X5FA 4IXED 1RD7A 3Q1HA 1HFPA 3SA1A 3SRWX 3NXYA 3FY9X 3SRRX 1J3KA 1KLKA 1PD8A 1OHJA 1DG7A 5DXVA 1JOMA 3FQOA 1DF7A 2DRCA 5HSRA 1DRAA 3QYOA 1M79A 4PSYA 3K74A 3QGTA 3NXVA 4DP3A 2ITHA 5CC9A 3GYFA 5DFRA 5JA3A 1M7AA 4KAKA 3SRUX 3NU0A 1QZFA 3EX8A 1D1GA 1U71A 2C2TA 2W9HA 3NXTA 3KJSA 3R33A 1DRFA 3GHWA 3KGYA 3FYVX
chains in the Genus database with same CATH superfamily
3DL6A 1DREA 4P3QA 4M2XA 5HQYA 3QLRA 5EAJA 5HF0X 1JUVA 1MVSA 1DR3A 4QHVA 2FZHA 4KFJA 4PSTA 4M7VA 3F0BX 4ECKA 2BLCA 4Q0DA 3E0BA 1BOZA 4HA7A 3FRAX 4M6KA 4P3RA 4KY4A 3JWMA 1DHJA 1BZFA 3CSEA 5JG0X 3S9UA 5HVEA 3QLXA 1DR6A 4HA9A 3SRSX 2W3BA 4Q0EA 1DR5A 4QJZD 4X5JA 2W3AA 1RX2A 4ELHA 3FL8A 5U26A 4M7UA 1DRBA 4EIZA 3NZAX 4KL9A 3SAIA 3CD2A 7DFRA 4HOGA 2B3ZA 1OHKA 2W3MA 3EEJA 3DL5A 1DG5A 3TQAA 1DIUA 1RF7A 4PTHA 3SGYA 3FY8X 2AZNA 2L28A 1U70A 4KJLA 3RO9A 3M08A 3LG4A 2BLBA 3K2HA 4I1NA 4CD2A 3NZ6X 3FRBX 2OIPA 3NXRA 4Q67A 5CCCA 4XECX 1DYJA 3NZBX 3L3RA 4TU5X 3F0QX 3FYWX 1DISA 3SH2A 8DFRA 4KM0A 3HJ3A 2W3WA 3SQYX 4ELFA 2HQPA 4DFRA 1RX8A 3S7AA 1CZ3A 1RX5A 3CLBA 3NTZA 4GH8A 3K45A 3QL0A 3JSUA 1LY4A 4KNEA 4KYAA 1DLRA 3NZDA 5HSUA 3FRFX 4ELGA 4M6LA 3NXOA 3M09A 3FQVA 4XT7A 2W9GA 1VJ3A 3GHCA 4KM2A 5HF2X 4G8ZX 5U27A 1J3IA 2FZIA 3I3RA 5HI6A 3NXXA 1M78A 4KJKA 4G3MA 1RX3A 1DR1A 2LF1A 3F0XX 4X5IA 5HT5A 3SA2A 2O7PA 1RX1A 1LY3A 5E8QA 2INQA 2QK8A 4KY8A 2D0KA 4KD7A 1MVTA 4KLXA 3GI2A 1TDRA 4H96A 4LAEX 1RA2A 5HVBA 1RX4A 1DYIA 4XT4A 3EEMA 3N0HA 4FGHA 4EJ1A 3TQ8A 1IA1A 4FHBA 3QLYA 2D5NA 3DG8A 3IROA 1RA3A 4DPDA 4H98A 1SEJA 4EILA 2HXVA 3UM8A 3D84X 3EIGA 1KMSA 3IA4A 1DYHA 1J3JA 2FZJA 3UM5A 1YHOA 3ZPGA 3FRDX 3UM6A 3F0SX 4QLGA 1IA3A 3OAFA 1DR2A 5ECCA 1S3WA 3JW5A 3D80A 3QYLA 1DYRA 1DDRA 3EELA 3F91A 3GHVA 4DPHA 3RG9A 3IRMA 4NX7A 3JW3A 1VDRA 2W3VA 1E26A 1RB3A 1DR7A 2JYBA 3TQ9A 3JWFA 3DGAA 4H95A 4P66A 4XT8A 3FQZA 1RH3A 3TD8A 1RA9A 3QLSA 4PSSA 3DRCA 3I8AX 1DHFA 1DG8A 1DR4A 3SR5X 2ZZAA 2DHFA 3IRNA 5HQZA 4PTJA 2W9TA 4X5GA 1S3VA 3QL3A 1RC4A 3KFYA 3NRRA 1RX7A 1RA8A 1RX9A 4QLFA 1RA1A 4IXFX 2CD2A 1HFQA 2GD9A 3IA5A 1RE7A 2BL9A 4LAGX 1DDSA 3CL9A 4G95A 1PD9A 3F0UX 1DLSA 4FGGA 1PDBA 3QLWA 3F0VX 3F8ZA 2HM9A 1JOLA 3DAUA 3FQ0A 4HOEA 3DFRA 5HT4A 1CD2A 3F8YA 4RGCA 5FDAA 3SRQX 1AO8A 4LAHX 3ROAA 3INVA 4KBNA 2XW7A 4P68A 1RG7A 1U72A 3FREX 3VCOA 2CIGA 4PDJA 4LEKX 4QI9A 1IA4A 3FQCA 3OCHA 1AOEA 3QG2A 4IXGX 3QLZA 2C2SA 4XE6X 4HOFA 2ANQA 3JWKA 1ZDRA 3S3VA 4Q6AA 1DRHA 1IA2A 5HPBA 3FQFA 3TQBA 3DATA 3FS6A 3QFXA 2BLAA 1DHIA 3JVXA 3NZCX 4KJJA 1AI9A 1RB2A 2P4GA 4H97A 3JWCA 5ECXA 4EIGA 3ZPCA 6DFRA 5HUIA 4QJCA 1HFRA 3KY8A 3EEKA 3K47A 4KEBA 4NX6A 4DDRA 1S3UA 3KJRA 1KMVA 1LUDA 4XT6A 3JTWA 3NZ9X 2H2QA 2KGKA 4OSGA 1RX6A 4OR7A 4QLEA 4XT5A 1DAJA 2W9SA 2OBCA 4ELEA 4I13A 3FL9A 1S3YA 4X5HA 3IX9A 4ELBA 3HBBA 2G6VA 4XRBA 4M6JA 2ANOA 4X5FA 4IXED 1RD7A 3Q1HA 1HFPA 3SA1A 3SRWX 3NXYA 3FY9X 3SRRX 1J3KA 1KLKA 1PD8A 1OHJA 1DG7A 5DXVA 1JOMA 3FQOA 1DF7A 2DRCA 5HSRA 1DRAA 3QYOA 1M79A 4PSYA 3K74A 3QGTA 3NXVA 4DP3A 2ITHA 5CC9A 3GYFA 5DFRA 5JA3A 1M7AA 4KAKA 3SRUX 3NU0A 1QZFA 3EX8A 1D1GA 1U71A 2C2TA 2W9HA 3NXTA 3KJSA 3R33A 1DRFA 3GHWA 3KGYA 3FYVX
chains in the Genus database with same CATH topology
3DL6A 1DREA 4P3QA 4M2XA 5HQYA 3QLRA 5EAJA 5HF0X 1JUVA 1MVSA 1DR3A 4QHVA 2FZHA 4KFJA 4PSTA 4M7VA 3F0BX 4ECKA 2BLCA 4Q0DA 3E0BA 1BOZA 4HA7A 3FRAX 4M6KA 4P3RA 4KY4A 3JWMA 1DHJA 1BZFA 3CSEA 5JG0X 3S9UA 5HVEA 3QLXA 1DR6A 4HA9A 3SRSX 2W3BA 4Q0EA 1DR5A 4QJZD 4X5JA 2W3AA 1RX2A 4ELHA 3FL8A 5U26A 4M7UA 1DRBA 4EIZA 3NZAX 4KL9A 3SAIA 3CD2A 7DFRA 4HOGA 2B3ZA 1OHKA 2W3MA 3EEJA 3DL5A 1DG5A 3TQAA 1DIUA 1RF7A 4PTHA 3SGYA 3FY8X 2AZNA 2L28A 1U70A 4KJLA 3RO9A 3M08A 3LG4A 2BLBA 3K2HA 4I1NA 4CD2A 3NZ6X 3FRBX 2OIPA 3NXRA 4Q67A 5CCCA 4XECX 1DYJA 3NZBX 3L3RA 4TU5X 3F0QX 3FYWX 1DISA 3SH2A 8DFRA 4KM0A 3HJ3A 2W3WA 3SQYX 4ELFA 2HQPA 4DFRA 1RX8A 3S7AA 1CZ3A 1RX5A 3CLBA 3NTZA 4GH8A 3K45A 3QL0A 3JSUA 1LY4A 4KNEA 4KYAA 1DLRA 3NZDA 5HSUA 3FRFX 4ELGA 4M6LA 3NXOA 3M09A 3FQVA 4XT7A 2W9GA 1VJ3A 3GHCA 4KM2A 5HF2X 4G8ZX 5U27A 1J3IA 2FZIA 3I3RA 5HI6A 3NXXA 1M78A 4KJKA 4G3MA 1RX3A 1DR1A 2LF1A 3F0XX 4X5IA 5HT5A 3SA2A 2O7PA 1RX1A 1LY3A 5E8QA 2INQA 2QK8A 4KY8A 2D0KA 4KD7A 1MVTA 4KLXA 3GI2A 1TDRA 4H96A 4LAEX 1RA2A 5HVBA 1RX4A 1DYIA 4XT4A 3EEMA 3N0HA 4FGHA 4EJ1A 3TQ8A 1IA1A 4FHBA 3QLYA 2D5NA 3DG8A 3IROA 1RA3A 4DPDA 4H98A 1SEJA 4EILA 2HXVA 3UM8A 3D84X 3EIGA 1KMSA 3IA4A 1DYHA 1J3JA 2FZJA 3UM5A 1YHOA 3ZPGA 3FRDX 3UM6A 3F0SX 4QLGA 1IA3A 3OAFA 1DR2A 5ECCA 1S3WA 3JW5A 3D80A 3QYLA 1DYRA 1DDRA 3EELA 3F91A 3GHVA 4DPHA 3RG9A 3IRMA 4NX7A 3JW3A 1VDRA 2W3VA 1E26A 1RB3A 1DR7A 2JYBA 3TQ9A 3JWFA 3DGAA 4H95A 4P66A 4XT8A 3FQZA 1RH3A 3TD8A 1RA9A 3QLSA 4PSSA 3DRCA 3I8AX 1DHFA 1DG8A 1DR4A 3SR5X 2ZZAA 2DHFA 3IRNA 5HQZA 4PTJA 2W9TA 4X5GA 1S3VA 3QL3A 1RC4A 3KFYA 3NRRA 1RX7A 1RA8A 1RX9A 4QLFA 1RA1A 4IXFX 2CD2A 1HFQA 2GD9A 3IA5A 1RE7A 2BL9A 4LAGX 1DDSA 3CL9A 4G95A 1PD9A 3F0UX 1DLSA 4FGGA 1PDBA 3QLWA 3F0VX 3F8ZA 2HM9A 1JOLA 3DAUA 3FQ0A 4HOEA 3DFRA 5HT4A 1CD2A 3F8YA 4RGCA 5FDAA 3SRQX 1AO8A 4LAHX 3ROAA 3INVA 4KBNA 2XW7A 4P68A 1RG7A 1U72A 3FREX 3VCOA 2CIGA 4PDJA 4LEKX 4QI9A 1IA4A 3FQCA 3OCHA 1AOEA 3QG2A 4IXGX 3QLZA 2C2SA 4XE6X 4HOFA 2ANQA 3JWKA 1ZDRA 3S3VA 4Q6AA 1DRHA 1IA2A 5HPBA 3FQFA 3TQBA 3DATA 3FS6A 3QFXA 2BLAA 1DHIA 3JVXA 3NZCX 4KJJA 1AI9A 1RB2A 2P4GA 4H97A 3JWCA 5ECXA 4EIGA 3ZPCA 6DFRA 5HUIA 4QJCA 1HFRA 3KY8A 3EEKA 3K47A 4KEBA 4NX6A 4DDRA 1S3UA 3KJRA 1KMVA 1LUDA 4XT6A 3JTWA 3NZ9X 2H2QA 2KGKA 4OSGA 1RX6A 4OR7A 4QLEA 4XT5A 1DAJA 2W9SA 2OBCA 4ELEA 4I13A 3FL9A 1S3YA 4X5HA 3IX9A 4ELBA 3HBBA 2G6VA 4XRBA 4M6JA 2ANOA 4X5FA 4IXED 1RD7A 3Q1HA 1HFPA 3SA1A 3SRWX 3NXYA 3FY9X 3SRRX 1J3KA 1KLKA 1PD8A 1OHJA 1DG7A 5DXVA 1JOMA 3FQOA 1DF7A 2DRCA 5HSRA 1DRAA 3QYOA 1M79A 4PSYA 3K74A 3QGTA 3NXVA 4DP3A 2ITHA 5CC9A 3GYFA 5DFRA 5JA3A 1M7AA 4KAKA 3SRUX 3NU0A 1QZFA 3EX8A 1D1GA 1U71A 2C2TA 2W9HA 3NXTA 3KJSA 3R33A 1DRFA 3GHWA 3KGYA 3FYVX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DL6 A;  1DRE A;  4P3Q A;  4M2X A;  5HQY A;  3QLR A;  5EAJ A;  5HF0 X;  1JUV A;  1MVS A;  1DR3 A;  4QHV A;  2FZH A;  4KFJ A;  4PST A;  4M7V A;  3F0B X;  4ECK A;  2BLC A;  4Q0D A;  3E0B A;  1BOZ A;  4HA7 A;  3FRA X;  4M6K A;  4P3R A;  4KY4 A;  3JWM A;  1DHJ A;  1BZF A;  3CSE A;  5JG0 X;  3S9U A;  5HVE A;  3QLX A;  1DR6 A;  4HA9 A;  3SRS X;  2W3B A;  4Q0E A;  1DR5 A;  4QJZ D;  4X5J A;  2W3A A;  1RX2 A;  4ELH A;  3FL8 A;  5U26 A;  4M7U A;  1DRB A;  4EIZ A;  3NZA X;  4KL9 A;  3SAI A;  3CD2 A;  7DFR A;  4HOG A;  2B3Z A;  1OHK A;  2W3M A;  3EEJ A;  3DL5 A;  1DG5 A;  3TQA A;  1DIU A;  1RF7 A;  4PTH A;  3SGY A;  3FY8 X;  2AZN A;  2L28 A;  1U70 A;  4KJL A;  3RO9 A;  3M08 A;  3LG4 A;  2BLB A;  3K2H A;  4I1N A;  4CD2 A;  3NZ6 X;  3FRB X;  2OIP A;  3NXR A;  4Q67 A;  5CCC A;  4XEC X;  1DYJ A;  3NZB X;  3L3R A;  4TU5 X;  3F0Q X;  3FYW X;  1DIS A;  3SH2 A;  8DFR A;  4KM0 A;  3HJ3 A;  2W3W A;  3SQY X;  4ELF A;  2HQP A;  4DFR A;  1RX8 A;  3S7A A;  1CZ3 A;  1RX5 A;  3CLB A;  3NTZ A;  4GH8 A;  3K45 A;  3QL0 A;  3JSU A;  1LY4 A;  4KNE A;  4KYA A;  1DLR A;  3NZD A;  5HSU A;  3FRF X;  4ELG A;  4M6L A;  3NXO A;  3M09 A;  3FQV A;  4XT7 A;  2W9G A;  1VJ3 A;  3GHC A;  4KM2 A;  5HF2 X;  4G8Z X;  5U27 A;  1J3I A;  2FZI A;  3I3R A;  5HI6 A;  3NXX A;  1M78 A;  4KJK A;  4G3M A;  1RX3 A;  1DR1 A;  2LF1 A;  3F0X X;  4X5I A;  5HT5 A;  3SA2 A;  2O7P A;  1RX1 A;  1LY3 A;  5E8Q A;  2INQ A;  2QK8 A;  4KY8 A;  2D0K A;  4KD7 A;  1MVT A;  4KLX A;  3GI2 A;  1TDR A;  4H96 A;  4LAE X;  1RA2 A;  5HVB A;  1RX4 A;  1DYI A;  4XT4 A;  3EEM A;  3N0H A;  4FGH A;  4EJ1 A;  3TQ8 A;  1IA1 A;  4FHB A;  3QLY A;  2D5N A;  3DG8 A;  3IRO A;  1RA3 A;  4DPD A;  4H98 A;  1SEJ A;  4EIL A;  2HXV A;  3UM8 A;  3D84 X;  3EIG A;  1KMS A;  3IA4 A;  1DYH A;  1J3J A;  2FZJ A;  3UM5 A;  1YHO A;  3ZPG A;  3FRD X;  3UM6 A;  3F0S X;  4QLG A;  1IA3 A;  3OAF A;  1DR2 A;  5ECC A;  1S3W A;  3JW5 A;  3D80 A;  3QYL A;  1DYR A;  1DDR A;  3EEL A;  3F91 A;  3GHV A;  4DPH A;  3RG9 A;  3IRM A;  4NX7 A;  3JW3 A;  1VDR A;  2W3V A;  1E26 A;  1RB3 A;  1DR7 A;  2JYB A;  3TQ9 A;  3JWF A;  3DGA A;  4H95 A;  4P66 A;  4XT8 A;  3FQZ A;  1RH3 A;  3TD8 A;  1RA9 A;  3QLS A;  4PSS A;  3DRC A;  3I8A X;  1DHF A;  1DG8 A;  1DR4 A;  3SR5 X;  2ZZA A;  2DHF A;  3IRN A;  5HQZ A;  4PTJ A;  2W9T A;  4X5G A;  1S3V A;  3QL3 A;  1RC4 A;  3KFY A;  3NRR A;  1RX7 A;  1RA8 A;  1RX9 A;  4QLF A;  1RA1 A;  4IXF X;  2CD2 A;  1HFQ A;  2GD9 A;  3IA5 A;  1RE7 A;  2BL9 A;  4LAG X;  1DDS A;  3CL9 A;  4G95 A;  1PD9 A;  3F0U X;  1DLS A;  4FGG A;  1PDB A;  3QLW A;  3F0V X;  3F8Z A;  2HM9 A;  1JOL A;  3DAU A;  3FQ0 A;  4HOE A;  3DFR A;  5HT4 A;  1CD2 A;  3F8Y A;  4RGC A;  5FDA A;  3SRQ X;  1AO8 A;  4LAH X;  3ROA A;  3INV A;  4KBN A;  2XW7 A;  4P68 A;  1RG7 A;  1U72 A;  3FRE X;  3VCO A;  2CIG A;  4PDJ A;  4LEK X;  4QI9 A;  1IA4 A;  3FQC A;  3OCH A;  1AOE A;  3QG2 A;  4IXG X;  3QLZ A;  2C2S A;  4XE6 X;  4HOF A;  2ANQ A;  3JWK A;  1ZDR A;  3S3V A;  4Q6A A;  1DRH A;  1IA2 A;  5HPB A;  3FQF A;  3TQB A;  3DAT A;  3FS6 A;  3QFX A;  2BLA A;  1DHI A;  3JVX A;  3NZC X;  4KJJ A;  1AI9 A;  1RB2 A;  2P4G A;  4H97 A;  3JWC A;  5ECX A;  4EIG A;  3ZPC A;  6DFR A;  5HUI A;  4QJC A;  1HFR A;  3KY8 A;  3EEK A;  3K47 A;  4KEB A;  4NX6 A;  4DDR A;  1S3U A;  3KJR A;  1KMV A;  1LUD A;  4XT6 A;  3JTW A;  3NZ9 X;  2H2Q A;  2KGK A;  4OSG A;  1RX6 A;  4OR7 A;  4QLE A;  4XT5 A;  1DAJ A;  2W9S A;  2OBC A;  4ELE A;  4I13 A;  3FL9 A;  1S3Y A;  4X5H A;  3IX9 A;  4ELB A;  3HBB A;  2G6V A;  4XRB A;  4M6J A;  2ANO A;  4X5F A;  4IXE D;  1RD7 A;  3Q1H A;  1HFP A;  3SA1 A;  3SRW X;  3NXY A;  3FY9 X;  3SRR X;  1J3K A;  1KLK A;  1PD8 A;  1OHJ A;  1DG7 A;  5DXV A;  1JOM A;  3FQO A;  1DF7 A;  2DRC A;  5HSR A;  1DRA A;  3QYO A;  1M79 A;  4PSY A;  3K74 A;  3QGT A;  3NXV A;  4DP3 A;  2ITH A;  5CC9 A;  3GYF A;  5DFR A;  5JA3 A;  1M7A A;  4KAK A;  3SRU X;  3NU0 A;  1QZF A;  3EX8 A;  1D1G A;  1U71 A;  2C2T A;  2W9H A;  3NXT A;  3KJS A;  3R33 A;  1DRF A;  3GHW A;  3KGY A;  3FYV X; 
#chains in the Genus database with same CATH topology
 3DL6 A;  1DRE A;  4P3Q A;  4M2X A;  5HQY A;  3QLR A;  5EAJ A;  5HF0 X;  1JUV A;  1MVS A;  1DR3 A;  4QHV A;  2FZH A;  4KFJ A;  4PST A;  4M7V A;  3F0B X;  4ECK A;  2BLC A;  4Q0D A;  3E0B A;  1BOZ A;  4HA7 A;  3FRA X;  4M6K A;  4P3R A;  4KY4 A;  3JWM A;  1DHJ A;  1BZF A;  3CSE A;  5JG0 X;  3S9U A;  5HVE A;  3QLX A;  1DR6 A;  4HA9 A;  3SRS X;  2W3B A;  4Q0E A;  1DR5 A;  4QJZ D;  4X5J A;  2W3A A;  1RX2 A;  4ELH A;  3FL8 A;  5U26 A;  4M7U A;  1DRB A;  4EIZ A;  3NZA X;  4KL9 A;  3SAI A;  3CD2 A;  7DFR A;  4HOG A;  2B3Z A;  1OHK A;  2W3M A;  3EEJ A;  3DL5 A;  1DG5 A;  3TQA A;  1DIU A;  1RF7 A;  4PTH A;  3SGY A;  3FY8 X;  2AZN A;  2L28 A;  1U70 A;  4KJL A;  3RO9 A;  3M08 A;  3LG4 A;  2BLB A;  3K2H A;  4I1N A;  4CD2 A;  3NZ6 X;  3FRB X;  2OIP A;  3NXR A;  4Q67 A;  5CCC A;  4XEC X;  1DYJ A;  3NZB X;  3L3R A;  4TU5 X;  3F0Q X;  3FYW X;  1DIS A;  3SH2 A;  8DFR A;  4KM0 A;  3HJ3 A;  2W3W A;  3SQY X;  4ELF A;  2HQP A;  4DFR A;  1RX8 A;  3S7A A;  1CZ3 A;  1RX5 A;  3CLB A;  3NTZ A;  4GH8 A;  3K45 A;  3QL0 A;  3JSU A;  1LY4 A;  4KNE A;  4KYA A;  1DLR A;  3NZD A;  5HSU A;  3FRF X;  4ELG A;  4M6L A;  3NXO A;  3M09 A;  3FQV A;  4XT7 A;  2W9G A;  1VJ3 A;  3GHC A;  4KM2 A;  5HF2 X;  4G8Z X;  5U27 A;  1J3I A;  2FZI A;  3I3R A;  5HI6 A;  3NXX A;  1M78 A;  4KJK A;  4G3M A;  1RX3 A;  1DR1 A;  2LF1 A;  3F0X X;  4X5I A;  5HT5 A;  3SA2 A;  2O7P A;  1RX1 A;  1LY3 A;  5E8Q A;  2INQ A;  2QK8 A;  4KY8 A;  2D0K A;  4KD7 A;  1MVT A;  4KLX A;  3GI2 A;  1TDR A;  4H96 A;  4LAE X;  1RA2 A;  5HVB A;  1RX4 A;  1DYI A;  4XT4 A;  3EEM A;  3N0H A;  4FGH A;  4EJ1 A;  3TQ8 A;  1IA1 A;  4FHB A;  3QLY A;  2D5N A;  3DG8 A;  3IRO A;  1RA3 A;  4DPD A;  4H98 A;  1SEJ A;  4EIL A;  2HXV A;  3UM8 A;  3D84 X;  3EIG A;  1KMS A;  3IA4 A;  1DYH A;  1J3J A;  2FZJ A;  3UM5 A;  1YHO A;  3ZPG A;  3FRD X;  3UM6 A;  3F0S X;  4QLG A;  1IA3 A;  3OAF A;  1DR2 A;  5ECC A;  1S3W A;  3JW5 A;  3D80 A;  3QYL A;  1DYR A;  1DDR A;  3EEL A;  3F91 A;  3GHV A;  4DPH A;  3RG9 A;  3IRM A;  4NX7 A;  3JW3 A;  1VDR A;  2W3V A;  1E26 A;  1RB3 A;  1DR7 A;  2JYB A;  3TQ9 A;  3JWF A;  3DGA A;  4H95 A;  4P66 A;  4XT8 A;  3FQZ A;  1RH3 A;  3TD8 A;  1RA9 A;  3QLS A;  4PSS A;  3DRC A;  3I8A X;  1DHF A;  1DG8 A;  1DR4 A;  3SR5 X;  2ZZA A;  2DHF A;  3IRN A;  5HQZ A;  4PTJ A;  2W9T A;  4X5G A;  1S3V A;  3QL3 A;  1RC4 A;  3KFY A;  3NRR A;  1RX7 A;  1RA8 A;  1RX9 A;  4QLF A;  1RA1 A;  4IXF X;  2CD2 A;  1HFQ A;  2GD9 A;  3IA5 A;  1RE7 A;  2BL9 A;  4LAG X;  1DDS A;  3CL9 A;  4G95 A;  1PD9 A;  3F0U X;  1DLS A;  4FGG A;  1PDB A;  3QLW A;  3F0V X;  3F8Z A;  2HM9 A;  1JOL A;  3DAU A;  3FQ0 A;  4HOE A;  3DFR A;  5HT4 A;  1CD2 A;  3F8Y A;  4RGC A;  5FDA A;  3SRQ X;  1AO8 A;  4LAH X;  3ROA A;  3INV A;  4KBN A;  2XW7 A;  4P68 A;  1RG7 A;  1U72 A;  3FRE X;  3VCO A;  2CIG A;  4PDJ A;  4LEK X;  4QI9 A;  1IA4 A;  3FQC A;  3OCH A;  1AOE A;  3QG2 A;  4IXG X;  3QLZ A;  2C2S A;  4XE6 X;  4HOF A;  2ANQ A;  3JWK A;  1ZDR A;  3S3V A;  4Q6A A;  1DRH A;  1IA2 A;  5HPB A;  3FQF A;  3TQB A;  3DAT A;  3FS6 A;  3QFX A;  2BLA A;  1DHI A;  3JVX A;  3NZC X;  4KJJ A;  1AI9 A;  1RB2 A;  2P4G A;  4H97 A;  3JWC A;  5ECX A;  4EIG A;  3ZPC A;  6DFR A;  5HUI A;  4QJC A;  1HFR A;  3KY8 A;  3EEK A;  3K47 A;  4KEB A;  4NX6 A;  4DDR A;  1S3U A;  3KJR A;  1KMV A;  1LUD A;  4XT6 A;  3JTW A;  3NZ9 X;  2H2Q A;  2KGK A;  4OSG A;  1RX6 A;  4OR7 A;  4QLE A;  4XT5 A;  1DAJ A;  2W9S A;  2OBC A;  4ELE A;  4I13 A;  3FL9 A;  1S3Y A;  4X5H A;  3IX9 A;  4ELB A;  3HBB A;  2G6V A;  4XRB A;  4M6J A;  2ANO A;  4X5F A;  4IXE D;  1RD7 A;  3Q1H A;  1HFP A;  3SA1 A;  3SRW X;  3NXY A;  3FY9 X;  3SRR X;  1J3K A;  1KLK A;  1PD8 A;  1OHJ A;  1DG7 A;  5DXV A;  1JOM A;  3FQO A;  1DF7 A;  2DRC A;  5HSR A;  1DRA A;  3QYO A;  1M79 A;  4PSY A;  3K74 A;  3QGT A;  3NXV A;  4DP3 A;  2ITH A;  5CC9 A;  3GYF A;  5DFR A;  5JA3 A;  1M7A A;  4KAK A;  3SRU X;  3NU0 A;  1QZF A;  3EX8 A;  1D1G A;  1U71 A;  2C2T A;  2W9H A;  3NXT A;  3KJS A;  3R33 A;  1DRF A;  3GHW A;  3KGY A;  3FYV X; 
#chains in the Genus database with same CATH homology
 3DL6 A;  1DRE A;  4P3Q A;  4M2X A;  5HQY A;  3QLR A;  5EAJ A;  5HF0 X;  1JUV A;  1MVS A;  1DR3 A;  4QHV A;  2FZH A;  4KFJ A;  4PST A;  4M7V A;  3F0B X;  4ECK A;  2BLC A;  4Q0D A;  3E0B A;  1BOZ A;  4HA7 A;  3FRA X;  4M6K A;  4P3R A;  4KY4 A;  3JWM A;  1DHJ A;  1BZF A;  3CSE A;  5JG0 X;  3S9U A;  5HVE A;  3QLX A;  1DR6 A;  4HA9 A;  3SRS X;  2W3B A;  4Q0E A;  1DR5 A;  4QJZ D;  4X5J A;  2W3A A;  1RX2 A;  4ELH A;  3FL8 A;  5U26 A;  4M7U A;  1DRB A;  4EIZ A;  3NZA X;  4KL9 A;  3SAI A;  3CD2 A;  7DFR A;  4HOG A;  2B3Z A;  1OHK A;  2W3M A;  3EEJ A;  3DL5 A;  1DG5 A;  3TQA A;  1DIU A;  1RF7 A;  4PTH A;  3SGY A;  3FY8 X;  2AZN A;  2L28 A;  1U70 A;  4KJL A;  3RO9 A;  3M08 A;  3LG4 A;  2BLB A;  3K2H A;  4I1N A;  4CD2 A;  3NZ6 X;  3FRB X;  2OIP A;  3NXR A;  4Q67 A;  5CCC A;  4XEC X;  1DYJ A;  3NZB X;  3L3R A;  4TU5 X;  3F0Q X;  3FYW X;  1DIS A;  3SH2 A;  8DFR A;  4KM0 A;  3HJ3 A;  2W3W A;  3SQY X;  4ELF A;  2HQP A;  4DFR A;  1RX8 A;  3S7A A;  1CZ3 A;  1RX5 A;  3CLB A;  3NTZ A;  4GH8 A;  3K45 A;  3QL0 A;  3JSU A;  1LY4 A;  4KNE A;  4KYA A;  1DLR A;  3NZD A;  5HSU A;  3FRF X;  4ELG A;  4M6L A;  3NXO A;  3M09 A;  3FQV A;  4XT7 A;  2W9G A;  1VJ3 A;  3GHC A;  4KM2 A;  5HF2 X;  4G8Z X;  5U27 A;  1J3I A;  2FZI A;  3I3R A;  5HI6 A;  3NXX A;  1M78 A;  4KJK A;  4G3M A;  1RX3 A;  1DR1 A;  2LF1 A;  3F0X X;  4X5I A;  5HT5 A;  3SA2 A;  2O7P A;  1RX1 A;  1LY3 A;  5E8Q A;  2INQ A;  2QK8 A;  4KY8 A;  2D0K A;  4KD7 A;  1MVT A;  4KLX A;  3GI2 A;  1TDR A;  4H96 A;  4LAE X;  1RA2 A;  5HVB A;  1RX4 A;  1DYI A;  4XT4 A;  3EEM A;  3N0H A;  4FGH A;  4EJ1 A;  3TQ8 A;  1IA1 A;  4FHB A;  3QLY A;  2D5N A;  3DG8 A;  3IRO A;  1RA3 A;  4DPD A;  4H98 A;  1SEJ A;  4EIL A;  2HXV A;  3UM8 A;  3D84 X;  3EIG A;  1KMS A;  3IA4 A;  1DYH A;  1J3J A;  2FZJ A;  3UM5 A;  1YHO A;  3ZPG A;  3FRD X;  3UM6 A;  3F0S X;  4QLG A;  1IA3 A;  3OAF A;  1DR2 A;  5ECC A;  1S3W A;  3JW5 A;  3D80 A;  3QYL A;  1DYR A;  1DDR A;  3EEL A;  3F91 A;  3GHV A;  4DPH A;  3RG9 A;  3IRM A;  4NX7 A;  3JW3 A;  1VDR A;  2W3V A;  1E26 A;  1RB3 A;  1DR7 A;  2JYB A;  3TQ9 A;  3JWF A;  3DGA A;  4H95 A;  4P66 A;  4XT8 A;  3FQZ A;  1RH3 A;  3TD8 A;  1RA9 A;  3QLS A;  4PSS A;  3DRC A;  3I8A X;  1DHF A;  1DG8 A;  1DR4 A;  3SR5 X;  2ZZA A;  2DHF A;  3IRN A;  5HQZ A;  4PTJ A;  2W9T A;  4X5G A;  1S3V A;  3QL3 A;  1RC4 A;  3KFY A;  3NRR A;  1RX7 A;  1RA8 A;  1RX9 A;  4QLF A;  1RA1 A;  4IXF X;  2CD2 A;  1HFQ A;  2GD9 A;  3IA5 A;  1RE7 A;  2BL9 A;  4LAG X;  1DDS A;  3CL9 A;  4G95 A;  1PD9 A;  3F0U X;  1DLS A;  4FGG A;  1PDB A;  3QLW A;  3F0V X;  3F8Z A;  2HM9 A;  1JOL A;  3DAU A;  3FQ0 A;  4HOE A;  3DFR A;  5HT4 A;  1CD2 A;  3F8Y A;  4RGC A;  5FDA A;  3SRQ X;  1AO8 A;  4LAH X;  3ROA A;  3INV A;  4KBN A;  2XW7 A;  4P68 A;  1RG7 A;  1U72 A;  3FRE X;  3VCO A;  2CIG A;  4PDJ A;  4LEK X;  4QI9 A;  1IA4 A;  3FQC A;  3OCH A;  1AOE A;  3QG2 A;  4IXG X;  3QLZ A;  2C2S A;  4XE6 X;  4HOF A;  2ANQ A;  3JWK A;  1ZDR A;  3S3V A;  4Q6A A;  1DRH A;  1IA2 A;  5HPB A;  3FQF A;  3TQB A;  3DAT A;  3FS6 A;  3QFX A;  2BLA A;  1DHI A;  3JVX A;  3NZC X;  4KJJ A;  1AI9 A;  1RB2 A;  2P4G A;  4H97 A;  3JWC A;  5ECX A;  4EIG A;  3ZPC A;  6DFR A;  5HUI A;  4QJC A;  1HFR A;  3KY8 A;  3EEK A;  3K47 A;  4KEB A;  4NX6 A;  4DDR A;  1S3U A;  3KJR A;  1KMV A;  1LUD A;  4XT6 A;  3JTW A;  3NZ9 X;  2H2Q A;  2KGK A;  4OSG A;  1RX6 A;  4OR7 A;  4QLE A;  4XT5 A;  1DAJ A;  2W9S A;  2OBC A;  4ELE A;  4I13 A;  3FL9 A;  1S3Y A;  4X5H A;  3IX9 A;  4ELB A;  3HBB A;  2G6V A;  4XRB A;  4M6J A;  2ANO A;  4X5F A;  4IXE D;  1RD7 A;  3Q1H A;  1HFP A;  3SA1 A;  3SRW X;  3NXY A;  3FY9 X;  3SRR X;  1J3K A;  1KLK A;  1PD8 A;  1OHJ A;  1DG7 A;  5DXV A;  1JOM A;  3FQO A;  1DF7 A;  2DRC A;  5HSR A;  1DRA A;  3QYO A;  1M79 A;  4PSY A;  3K74 A;  3QGT A;  3NXV A;  4DP3 A;  2ITH A;  5CC9 A;  3GYF A;  5DFR A;  5JA3 A;  1M7A A;  4KAK A;  3SRU X;  3NU0 A;  1QZF A;  3EX8 A;  1D1G A;  1U71 A;  2C2T A;  2W9H A;  3NXT A;  3KJS A;  3R33 A;  1DRF A;  3GHW A;  3KGY A;  3FYV X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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