3QN2A

Structure-based design of a disulfide-linked oligomeric form of the simian virus 40 (sv40) large t antigen dna binding domain
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
127
structure length
126
Chain Sequence
KVEDPKDFPSELLSFLSHAVCSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLATFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLEHCF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Large T antigen
publication title Structure-based design of a disulfide-linked oligomeric form of the simian virus 40 (SV40) large T antigen DNA-binding domain.
pubmed doi rcsb
source organism Simian virus 40
total genus 30
structure length 126
sequence length 127
ec nomenclature ec 3.6.4.-:
pdb deposition date 2011-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 3qn2A00
3QFQA 2IF9A 2NTCA 1UUTA 2TBDA 1L5IA 1TBDA 2FUFA 4ZQ9A 2NL8A 3QN2A 4NBPA 5BYGA 5D9IA 1L2MA 1RZ9A 1M55A 4FGNA 2HW0A 2IPRA 4GDFA 5DCXA 5CYNA 4LMDA 4FB3A 2ITLA 4ZO0A 3QK2A 4LIFA 1Z1DB 2ITJA
chains in the Genus database with same CATH superfamily
3QFQA 1KSXA 2IF9A 2NTCA 1F08A 1UUTA 2TBDA 1L5IA 3DKXA 1TBDA 2FUFA 4ZQ9A 2NL8A 3QN2A 4NBPA 5BYGA 5D9IA 1L2MA 1R9WA 1RZ9A 1M55A 4FGNA 2HW0A 2IPRA 4GDFA 5DCXA 5CYNA 3DKYA 4LMDA 4FB3A 1KSYA 2ITLA 4ZO0A 3QK2A 4LIFA 4U87A 1Z1DB 4KW3A 2ITJA
chains in the Genus database with same CATH topology
3QFQA 1KSXA 2IF9A 2NTCA 1F08A 1UUTA 2TBDA 1L5IA 3DKXA 1TBDA 2FUFA 4ZQ9A 2NL8A 3QN2A 4NBPA 5BYGA 5D9IA 1L2MA 1R9WA 1RZ9A 1M55A 4FGNA 2HW0A 2IPRA 4GDFA 5DCXA 5CYNA 3DKYA 4LMDA 4FB3A 1KSYA 2ITLA 4ZO0A 3QK2A 4LIFA 4U87A 1Z1DB 4KW3A 2ITJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QFQ A;  2IF9 A;  2NTC A;  1UUT A;  2TBD A;  1L5I A;  1TBD A;  2FUF A;  4ZQ9 A;  2NL8 A;  3QN2 A;  4NBP A;  5BYG A;  5D9I A;  1L2M A;  1RZ9 A;  1M55 A;  4FGN A;  2HW0 A;  2IPR A;  4GDF A;  5DCX A;  5CYN A;  4LMD A;  4FB3 A;  2ITL A;  4ZO0 A;  3QK2 A;  4LIF A;  1Z1D B;  2ITJ A; 
#chains in the Genus database with same CATH topology
 3QFQ A;  1KSX A;  2IF9 A;  2NTC A;  1F08 A;  1UUT A;  2TBD A;  1L5I A;  3DKX A;  1TBD A;  2FUF A;  4ZQ9 A;  2NL8 A;  3QN2 A;  4NBP A;  5BYG A;  5D9I A;  1L2M A;  1R9W A;  1RZ9 A;  1M55 A;  4FGN A;  2HW0 A;  2IPR A;  4GDF A;  5DCX A;  5CYN A;  3DKY A;  4LMD A;  4FB3 A;  1KSY A;  2ITL A;  4ZO0 A;  3QK2 A;  4LIF A;  4U87 A;  1Z1D B;  4KW3 A;  2ITJ A; 
#chains in the Genus database with same CATH homology
 3QFQ A;  1KSX A;  2IF9 A;  2NTC A;  1F08 A;  1UUT A;  2TBD A;  1L5I A;  3DKX A;  1TBD A;  2FUF A;  4ZQ9 A;  2NL8 A;  3QN2 A;  4NBP A;  5BYG A;  5D9I A;  1L2M A;  1R9W A;  1RZ9 A;  1M55 A;  4FGN A;  2HW0 A;  2IPR A;  4GDF A;  5DCX A;  5CYN A;  3DKY A;  4LMD A;  4FB3 A;  1KSY A;  2ITL A;  4ZO0 A;  3QK2 A;  4LIF A;  4U87 A;  1Z1D B;  4KW3 A;  2ITJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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