3QVFA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with mgadp and fosfomycin vanadate
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
274
structure length
274
Chain Sequence
HHSSGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFGHGAIRDHDSTHAFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDGAGGDTILPEVDARSPEQAYAALWGSSEWDATGAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
source organism Streptomyces wedmorensis
molecule tags Transferase
molecule keywords FomA protein
total genus 84
structure length 274
sequence length 274
ec nomenclature
pdb deposition date 2011-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3qvfA00
3S6KA 2BTYA 2J4JA 1OHBA 3WWNA 2AP9A 3ZZGA 2BNEA 2R8VA 4A7WA 2R98A 2WE4A 2E9YA 1GSJA 3LKKA 3AAWA 2IJ9A 2J5VA 1YBDA 3T7BA 3C20A 3QVHA 2V5HA 1OHAA 3D41A 4Q1TA 3ZZFA 2OGXB 3WWMA 2AKOA 4USJA 2BRXA 2A1FA 3K52A 4NDPA 3D2MA 2J5TA 3AB4A 4NDQA 3U6UA 4NDQB 2V4YA 4JZ9A 3ZZIA 2BRIA 1E19A 2J0XA 3EK5A 4NDOB 2HMFA 3C1NA 4NDRA 2BNFA 2J0WA 2WXBA 3C1MA 2JI5A 3K4YA 3D40A 3KZFA 4A7XA 3QUNA 3L86A 2J4KA 2J4LA 2RD5A 3TVIA 1GS5A 2CDQA 1Z9DA 3LL5A 3S6GA 3ZZHA 4OLCA 4JZ7A 3D2PA 4F6TA 2X2WA 2W21A 4AXSA 4NDRB 3QVFA 3AB2A 4NDOA 2JJ4A 3QURA 3NWYA 2BNDA 1OH9A 2WE5A 3B8GA 3S6HA 2BMUA 3LL9A 3L76A 3QUOA 4KZTA 4AB7A 4NDPB 4I49A 4JZ8A 3K56A 3K4OA 2OGXA 3EK6A 1B7BA 2BUFA 4F6TB 2JJXA 2VA1A
chains in the Genus database with same CATH superfamily
3S6KA 2BTYA 2J4JA 1OHBA 3WWNA 2AP9A 3ZZGA 2BNEA 2R8VA 4A7WA 2R98A 2WE4A 2E9YA 1GSJA 3LKKA 3AAWA 2IJ9A 2J5VA 1YBDA 3T7BA 3C20A 3QVHA 2V5HA 1OHAA 3D41A 4Q1TA 3ZZFA 2OGXB 3WWMA 2AKOA 4USJA 2BRXA 2A1FA 3K52A 4NDPA 3D2MA 2J5TA 3AB4A 4NDQA 3U6UA 4NDQB 2V4YA 4JZ9A 3ZZIA 2BRIA 1E19A 2J0XA 3EK5A 4NDOB 2HMFA 3C1NA 4NDRA 2BNFA 2J0WA 2WXBA 3C1MA 2JI5A 3K4YA 3D40A 3KZFA 4A7XA 3QUNA 3L86A 2J4KA 2J4LA 2RD5A 3TVIA 1GS5A 2CDQA 1Z9DA 3LL5A 3S6GA 3ZZHA 4OLCA 4JZ7A 3D2PA 4F6TA 2X2WA 2W21A 4AXSA 4NDRB 3QVFA 3AB2A 4NDOA 2JJ4A 3QURA 3NWYA 2BNDA 1OH9A 2WE5A 3B8GA 3S6HA 2BMUA 3LL9A 3L76A 3QUOA 4KZTA 4AB7A 4NDPB 4I49A 4JZ8A 3K56A 3K4OA 2OGXA 3EK6A 1B7BA 2BUFA 4F6TB 2JJXA 2VA1A
chains in the Genus database with same CATH topology
3S6KA 2BTYA 2J4JA 1OHBA 3WWNA 2AP9A 3ZZGA 2BNEA 2R8VA 4A7WA 2R98A 2WE4A 2E9YA 1GSJA 3LKKA 3AAWA 2IJ9A 2J5VA 1YBDA 3T7BA 3C20A 3QVHA 2V5HA 1OHAA 3D41A 4Q1TA 3ZZFA 2OGXB 3WWMA 2AKOA 4USJA 2BRXA 2A1FA 3K52A 4NDPA 3D2MA 2J5TA 3AB4A 4NDQA 3U6UA 4NDQB 2V4YA 4JZ9A 3ZZIA 2BRIA 1E19A 2J0XA 3EK5A 4NDOB 2HMFA 3C1NA 4NDRA 2BNFA 2J0WA 2WXBA 3C1MA 2JI5A 3K4YA 3D40A 3KZFA 4A7XA 3QUNA 3L86A 2J4KA 2J4LA 2RD5A 3TVIA 1GS5A 2CDQA 1Z9DA 3LL5A 3S6GA 3ZZHA 4OLCA 4JZ7A 3D2PA 4F6TA 2X2WA 2W21A 4AXSA 4NDRB 3QVFA 3AB2A 4NDOA 2JJ4A 3QURA 3NWYA 2BNDA 1OH9A 2WE5A 3B8GA 3S6HA 2BMUA 3LL9A 3L76A 3QUOA 4KZTA 4AB7A 4NDPB 4I49A 4JZ8A 3K56A 3K4OA 2OGXA 3EK6A 1B7BA 2BUFA 4F6TB 2JJXA 2VA1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S6K A;  2BTY A;  2J4J A;  1OHB A;  3WWN A;  2AP9 A;  3ZZG A;  2BNE A;  2R8V A;  4A7W A;  2R98 A;  2WE4 A;  2E9Y A;  1GSJ A;  3LKK A;  3AAW A;  2IJ9 A;  2J5V A;  1YBD A;  3T7B A;  3C20 A;  3QVH A;  2V5H A;  1OHA A;  3D41 A;  4Q1T A;  3ZZF A;  2OGX B;  3WWM A;  2AKO A;  4USJ A;  2BRX A;  2A1F A;  3K52 A;  4NDP A;  3D2M A;  2J5T A;  3AB4 A;  4NDQ A;  3U6U A;  4NDQ B;  2V4Y A;  4JZ9 A;  3ZZI A;  2BRI A;  1E19 A;  2J0X A;  3EK5 A;  4NDO B;  2HMF A;  3C1N A;  4NDR A;  2BNF A;  2J0W A;  2WXB A;  3C1M A;  2JI5 A;  3K4Y A;  3D40 A;  3KZF A;  4A7X A;  3QUN A;  3L86 A;  2J4K A;  2J4L A;  2RD5 A;  3TVI A;  1GS5 A;  2CDQ A;  1Z9D A;  3LL5 A;  3S6G A;  3ZZH A;  4OLC A;  4JZ7 A;  3D2P A;  4F6T A;  2X2W A;  2W21 A;  4AXS A;  4NDR B;  3QVF A;  3AB2 A;  4NDO A;  2JJ4 A;  3QUR A;  3NWY A;  2BND A;  1OH9 A;  2WE5 A;  3B8G A;  3S6H A;  2BMU A;  3LL9 A;  3L76 A;  3QUO A;  4KZT A;  4AB7 A;  4NDP B;  4I49 A;  4JZ8 A;  3K56 A;  3K4O A;  2OGX A;  3EK6 A;  1B7B A;  2BUF A;  4F6T B;  2JJX A;  2VA1 A; 
#chains in the Genus database with same CATH topology
 3S6K A;  2BTY A;  2J4J A;  1OHB A;  3WWN A;  2AP9 A;  3ZZG A;  2BNE A;  2R8V A;  4A7W A;  2R98 A;  2WE4 A;  2E9Y A;  1GSJ A;  3LKK A;  3AAW A;  2IJ9 A;  2J5V A;  1YBD A;  3T7B A;  3C20 A;  3QVH A;  2V5H A;  1OHA A;  3D41 A;  4Q1T A;  3ZZF A;  2OGX B;  3WWM A;  2AKO A;  4USJ A;  2BRX A;  2A1F A;  3K52 A;  4NDP A;  3D2M A;  2J5T A;  3AB4 A;  4NDQ A;  3U6U A;  4NDQ B;  2V4Y A;  4JZ9 A;  3ZZI A;  2BRI A;  1E19 A;  2J0X A;  3EK5 A;  4NDO B;  2HMF A;  3C1N A;  4NDR A;  2BNF A;  2J0W A;  2WXB A;  3C1M A;  2JI5 A;  3K4Y A;  3D40 A;  3KZF A;  4A7X A;  3QUN A;  3L86 A;  2J4K A;  2J4L A;  2RD5 A;  3TVI A;  1GS5 A;  2CDQ A;  1Z9D A;  3LL5 A;  3S6G A;  3ZZH A;  4OLC A;  4JZ7 A;  3D2P A;  4F6T A;  2X2W A;  2W21 A;  4AXS A;  4NDR B;  3QVF A;  3AB2 A;  4NDO A;  2JJ4 A;  3QUR A;  3NWY A;  2BND A;  1OH9 A;  2WE5 A;  3B8G A;  3S6H A;  2BMU A;  3LL9 A;  3L76 A;  3QUO A;  4KZT A;  4AB7 A;  4NDP B;  4I49 A;  4JZ8 A;  3K56 A;  3K4O A;  2OGX A;  3EK6 A;  1B7B A;  2BUF A;  4F6T B;  2JJX A;  2VA1 A; 
#chains in the Genus database with same CATH homology
 3S6K A;  2BTY A;  2J4J A;  1OHB A;  3WWN A;  2AP9 A;  3ZZG A;  2BNE A;  2R8V A;  4A7W A;  2R98 A;  2WE4 A;  2E9Y A;  1GSJ A;  3LKK A;  3AAW A;  2IJ9 A;  2J5V A;  1YBD A;  3T7B A;  3C20 A;  3QVH A;  2V5H A;  1OHA A;  3D41 A;  4Q1T A;  3ZZF A;  2OGX B;  3WWM A;  2AKO A;  4USJ A;  2BRX A;  2A1F A;  3K52 A;  4NDP A;  3D2M A;  2J5T A;  3AB4 A;  4NDQ A;  3U6U A;  4NDQ B;  2V4Y A;  4JZ9 A;  3ZZI A;  2BRI A;  1E19 A;  2J0X A;  3EK5 A;  4NDO B;  2HMF A;  3C1N A;  4NDR A;  2BNF A;  2J0W A;  2WXB A;  3C1M A;  2JI5 A;  3K4Y A;  3D40 A;  3KZF A;  4A7X A;  3QUN A;  3L86 A;  2J4K A;  2J4L A;  2RD5 A;  3TVI A;  1GS5 A;  2CDQ A;  1Z9D A;  3LL5 A;  3S6G A;  3ZZH A;  4OLC A;  4JZ7 A;  3D2P A;  4F6T A;  2X2W A;  2W21 A;  4AXS A;  4NDR B;  3QVF A;  3AB2 A;  4NDO A;  2JJ4 A;  3QUR A;  3NWY A;  2BND A;  1OH9 A;  2WE5 A;  3B8G A;  3S6H A;  2BMU A;  3LL9 A;  3L76 A;  3QUO A;  4KZT A;  4AB7 A;  4NDP B;  4I49 A;  4JZ8 A;  3K56 A;  3K4O A;  2OGX A;  3EK6 A;  1B7B A;  2BUF A;  4F6T B;  2JJX A;  2VA1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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