The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
143
|
sequence length |
453
|
structure length |
445
|
Chain Sequence |
TMSFFDLLNERAKRSLLCVGLDPRAKTAAAAVEECKRLIEQTHEYAAAYKPNAAFFEFFGAEGWAALSEVIRAVPAGIPVVLDAKRGDIADTADAYATSAFKHLNAHAITASPYMGSDSLQPFMRYPDKAVFVLCKTSNKGSNDLQCLRVGDRYLYEAVAERAEGPWNVNGNVGLVVGATDPVALARVRARAPTLWFLVPGIGAQGGSLKASLDAGLRADGSGMLINVSRGLARAADPRAAAKELCEEINAIRFAKGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMRLVAREYAKVLRHYKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAAIEGEYKKGDRVVIIDDLVSTETKVEAIEKLRSAGLEVVSIVVLVDRDMGAKAFLNKLGYDFEAVVGLHQLLPLWRKSNAITSQQEADVRAFLGQW
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
molecule tags |
Transferase, lyase
|
source organism |
Leishmania donovani
|
publication title |
The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.
pubmed doi rcsb |
molecule keywords |
UMP synthase
|
total genus |
143
|
structure length |
445
|
sequence length |
453
|
chains with identical sequence |
C
|
ec nomenclature |
ec
2.4.2.10: Orotate phosphoribosyltransferase. |
pdb deposition date | 2011-02-26 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
B | PF00156 | Pribosyltran | Phosphoribosyl transferase domain |
B | PF00215 | OMPdecase | Orotidine 5'-phosphate decarboxylase / HUMPS family |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Aldolase class I | ||
Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Rossmann fold |