3R5WA

Structure of ddn, the deazaflavin-dependent nitroreductase from mycobacterium tuberculosis involved in bioreductive activation of pa-824, with co-factor f420
Total Genus 31
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
109
structure length
109
Chain Sequence
KIPVALLTTTGRKTGQPRVNPLYFLRDGGRVIVAASKGGAEKNPMWYLNLKANPKVQVQIKKEVLDLTARDATDEERAEYWPQLVTMYPSYQDYQSWTDRTIPIVVCEP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
molecule keywords Deazaflavin-dependent nitroreductase
total genus 31
structure length 109
sequence length 109
chains with identical sequence B, C, D, E, K, L, M, N, O
ec nomenclature ec 1.-.-.-:
pdb deposition date 2011-03-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.110.10 Mainly Beta Roll Pnp Oxidase; Chain A Electron Transport, Fmn-binding Protein; Chain A 3r5wA00
3A6QA 1EJEA 1I0SA 3K88A 2OU5A 4N7RC 1AXJA 3ZOGA 1Y30A 2HTIA 2E83A 3HMZA 3VY5A 3ZOHA 3EC6A 3R5YA 3FGEA 4XHYA 1W3QA 2IG6A 5JABA 4Y9IA 4XJ2A 1G77A 1DNLA 1TY9A 1WLIA 4R82A 2FG9A 2FHQA 3ZOCA 3R5WA 3DB0A 4HMTA 5CHOA 3DNHA 2QEAA 1G78A 1VL7A 1RZ1A 5ESCA 2ASFA 2ED4A 1USCA 3BA3A 4HMSA 3H96A 2R6VA 3K87A 2I02A 4HMVA 3AMFA 3E4VA 1W9AA 1JNWA 1WLKA 2X1KA 3DMBA 3VYAA 2FURA 3U35A 3RH7A 2GJGA 2ECUA 4F07A 1XXOA 2VPAA 3PFTA 3AWHA 2ECRA 1G79A 3U5WA 3BPKA 3R5PA 4YWNA 1CI0A 1YOAA 1T9MA 1FLMA 1USFA 2IABA 1W3RA 3KYFA 3CP3A 4L82A 2HQ9A 1WGBA 2D5MA 3R5LA 3ZOFA 2I51A 1W3PA 2D37A 2RE7A 3KYGA 2QCKA 4HMUA 2NR4A 3A20A 2D36A 2OL5A 1W3OA 3K86A 1RFEA 2Q9KA 2X1JA 3FKHA 3HY8A 4HX6A 3U0IA 2HTDA 3B5MA 3NFWA 2ARZA 3BNKA 4HMWA 3A6RA 1G76A 1NRGA 2RDEA 2AQ6A 5BNCA 2IMLA 2R0XA 4Z85A 3IN6A 4QVBA 3GASA 3ZODA 1YLNA 1WV4A 3R5ZA 3R5RA 4ZKYA 2D38A 3CB0A 4HMXA 1RZ0A 4IRAA 3TGVA 3VY2A 3ZOEA 2HHZA 3F7EA 4YBNA 2PTFA 2HQ7A 1XHNA 2A2JA 1I0RA 3SWJA 3U34A 5CHEC
chains in the Genus database with same CATH superfamily
3A6QA 1EJEA 1I0SA 3K88A 2OU5A 4N7RC 1AXJA 3ZOGA 1Y30A 2HTIA 2E83A 3HMZA 3VY5A 3ZOHA 3EC6A 3R5YA 2K4QA 3FGEA 4UHVA 1W3QA 4XHYA 2IG6A 5JABA 4Y9IA 4XJ2A 1G77A 1DNLA 1TY9A 1WLIA 4R82A 2FG9A 2FHQA 3ZOCA 3R5WA 3DB0A 4HMTA 5CHOA 3DNHA 2QEAA 1G78A 1VL7A 1RZ1A 5ESCA 2ASFA 2ED4A 1USCA 3BA3A 4HMSA 3H96A 2R6VA 3K87A 2I02A 4HMVA 3AMFA 3E4VA 1W9AA 1JNWA 1WLKA 2X1KA 3DMBA 3VYAA 2FURA 3U35A 4W64A 3RH7A 2GJGA 2ECUA 4F07A 1XXOA 2VPAA 3PFTA 3AWHA 2ECRA 1G79A 3U5WA 3BPKA 2L1TA 3R5PA 4YWNA 1CI0A 1YOAA 1T9MA 1FLMA 1USFA 2IABA 4TV4A 1Y12A 1W3RA 3KYFA 3CP3A 4L82A 2HQ9A 1WGBA 2D5MA 3R5LA 3ZOFA 2I51A 1W3PA 2D37A 2RE7A 3KYGA 2QCKA 4HMUA 2NR4A 4MTKA 3A20A 2D36A 2OL5A 1W3OA 3EAAA 1RFEA 3K86A 2Q9KA 2X1JA 3FKHA 3HY8A 4HX6A 3U0IA 2HTDA 3B5MA 3NFWA 2ARZA 3BNKA 4HMWA 3A6RA 1G76A 1NRGA 2RDEA 2AQ6A 5BNCA 2IMLA 2R0XA 4Z85A 3IN6A 4QVBA 3GASA 3ZODA 1YLNA 1WV4A 3R5ZA 3V4HA 3R5RA 4ZKYA 2D38A 3CB0A 4HMXA 1RZ0A 2GUJA 4IRAA 3TGVA 3VY2A 2P5ZX 3HE1A 3ZOEA 2HHZA 3F7EA 4YBNA 2PTFA 2HQ7A 1XHNA 2A2JA 4HKHA 1I0RA 3SWJA 3U34A 5CHEC
chains in the Genus database with same CATH topology
3A6QA 1EJEA 1I0SA 3K88A 2OU5A 4N7RC 1AXJA 3ZOGA 1Y30A 2HTIA 2E83A 3HMZA 3VY5A 3ZOHA 3EC6A 3R5YA 3FGEA 4XHYA 1W3QA 2IG6A 5JABA 4Y9IA 4XJ2A 1G77A 1DNLA 1TY9A 1WLIA 4R82A 2FG9A 2FHQA 3ZOCA 3R5WA 3DB0A 4HMTA 5CHOA 3DNHA 2QEAA 1G78A 1VL7A 1RZ1A 5ESCA 2ASFA 2ED4A 1USCA 3BA3A 4HMSA 3H96A 2R6VA 3K87A 2I02A 4HMVA 3AMFA 3E4VA 1W9AA 1JNWA 1WLKA 2X1KA 3DMBA 3VYAA 2FURA 3U35A 3RH7A 2GJGA 2ECUA 4F07A 1XXOA 2VPAA 3PFTA 3AWHA 2ECRA 1G79A 3U5WA 3BPKA 3R5PA 4YWNA 1CI0A 1YOAA 1T9MA 1FLMA 1USFA 2IABA 1W3RA 3KYFA 3CP3A 4L82A 2HQ9A 1WGBA 2D5MA 3R5LA 3ZOFA 2I51A 1W3PA 2D37A 2RE7A 3KYGA 2QCKA 4HMUA 2NR4A 3A20A 2D36A 2OL5A 1W3OA 3K86A 1RFEA 2Q9KA 2X1JA 3FKHA 3HY8A 4HX6A 3U0IA 2HTDA 3B5MA 3NFWA 2ARZA 3BNKA 4HMWA 3A6RA 1G76A 1NRGA 2RDEA 2AQ6A 5BNCA 2IMLA 2R0XA 4Z85A 3IN6A 4QVBA 3GASA 3ZODA 1YLNA 1WV4A 3R5ZA 3R5RA 4ZKYA 2D38A 3CB0A 4HMXA 1RZ0A 4IRAA 3TGVA 3VY2A 3ZOEA 2HHZA 3F7EA 4YBNA 2PTFA 2HQ7A 1XHNA 2A2JA 1I0RA 3SWJA 3U34A 5CHEC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3A6Q A;  1EJE A;  1I0S A;  3K88 A;  2OU5 A;  4N7R C;  1AXJ A;  3ZOG A;  1Y30 A;  2HTI A;  2E83 A;  3HMZ A;  3VY5 A;  3ZOH A;  3EC6 A;  3R5Y A;  3FGE A;  4XHY A;  1W3Q A;  2IG6 A;  5JAB A;  4Y9I A;  4XJ2 A;  1G77 A;  1DNL A;  1TY9 A;  1WLI A;  4R82 A;  2FG9 A;  2FHQ A;  3ZOC A;  3R5W A;  3DB0 A;  4HMT A;  5CHO A;  3DNH A;  2QEA A;  1G78 A;  1VL7 A;  1RZ1 A;  5ESC A;  2ASF A;  2ED4 A;  1USC A;  3BA3 A;  4HMS A;  3H96 A;  2R6V A;  3K87 A;  2I02 A;  4HMV A;  3AMF A;  3E4V A;  1W9A A;  1JNW A;  1WLK A;  2X1K A;  3DMB A;  3VYA A;  2FUR A;  3U35 A;  3RH7 A;  2GJG A;  2ECU A;  4F07 A;  1XXO A;  2VPA A;  3PFT A;  3AWH A;  2ECR A;  1G79 A;  3U5W A;  3BPK A;  3R5P A;  4YWN A;  1CI0 A;  1YOA A;  1T9M A;  1FLM A;  1USF A;  2IAB A;  1W3R A;  3KYF A;  3CP3 A;  4L82 A;  2HQ9 A;  1WGB A;  2D5M A;  3R5L A;  3ZOF A;  2I51 A;  1W3P A;  2D37 A;  2RE7 A;  3KYG A;  2QCK A;  4HMU A;  2NR4 A;  3A20 A;  2D36 A;  2OL5 A;  1W3O A;  3K86 A;  1RFE A;  2Q9K A;  2X1J A;  3FKH A;  3HY8 A;  4HX6 A;  3U0I A;  2HTD A;  3B5M A;  3NFW A;  2ARZ A;  3BNK A;  4HMW A;  3A6R A;  1G76 A;  1NRG A;  2RDE A;  2AQ6 A;  5BNC A;  2IML A;  2R0X A;  4Z85 A;  3IN6 A;  4QVB A;  3GAS A;  3ZOD A;  1YLN A;  1WV4 A;  3R5Z A;  3R5R A;  4ZKY A;  2D38 A;  3CB0 A;  4HMX A;  1RZ0 A;  4IRA A;  3TGV A;  3VY2 A;  3ZOE A;  2HHZ A;  3F7E A;  4YBN A;  2PTF A;  2HQ7 A;  1XHN A;  2A2J A;  1I0R A;  3SWJ A;  3U34 A;  5CHE C; 
#chains in the Genus database with same CATH topology
 3A6Q A;  1EJE A;  1I0S A;  3K88 A;  2OU5 A;  4N7R C;  1AXJ A;  3ZOG A;  1Y30 A;  2HTI A;  2E83 A;  3HMZ A;  3VY5 A;  3ZOH A;  3EC6 A;  3R5Y A;  2K4Q A;  3FGE A;  4UHV A;  1W3Q A;  4XHY A;  2IG6 A;  5JAB A;  4Y9I A;  4XJ2 A;  1G77 A;  1DNL A;  1TY9 A;  1WLI A;  4R82 A;  2FG9 A;  2FHQ A;  3ZOC A;  3R5W A;  3DB0 A;  4HMT A;  5CHO A;  3DNH A;  2QEA A;  1G78 A;  1VL7 A;  1RZ1 A;  5ESC A;  2ASF A;  2ED4 A;  1USC A;  3BA3 A;  4HMS A;  3H96 A;  2R6V A;  3K87 A;  2I02 A;  4HMV A;  3AMF A;  3E4V A;  1W9A A;  1JNW A;  1WLK A;  2X1K A;  3DMB A;  3VYA A;  2FUR A;  3U35 A;  4W64 A;  3RH7 A;  2GJG A;  2ECU A;  4F07 A;  1XXO A;  2VPA A;  3PFT A;  3AWH A;  2ECR A;  1G79 A;  3U5W A;  3BPK A;  2L1T A;  3R5P A;  4YWN A;  1CI0 A;  1YOA A;  1T9M A;  1FLM A;  1USF A;  2IAB A;  4TV4 A;  1Y12 A;  1W3R A;  3KYF A;  3CP3 A;  4L82 A;  2HQ9 A;  1WGB A;  2D5M A;  3R5L A;  3ZOF A;  2I51 A;  1W3P A;  2D37 A;  2RE7 A;  3KYG A;  2QCK A;  4HMU A;  2NR4 A;  4MTK A;  3A20 A;  2D36 A;  2OL5 A;  1W3O A;  3EAA A;  1RFE A;  3K86 A;  2Q9K A;  2X1J A;  3FKH A;  3HY8 A;  4HX6 A;  3U0I A;  2HTD A;  3B5M A;  3NFW A;  2ARZ A;  3BNK A;  4HMW A;  3A6R A;  1G76 A;  1NRG A;  2RDE A;  2AQ6 A;  5BNC A;  2IML A;  2R0X A;  4Z85 A;  3IN6 A;  4QVB A;  3GAS A;  3ZOD A;  1YLN A;  1WV4 A;  3R5Z A;  3V4H A;  3R5R A;  4ZKY A;  2D38 A;  3CB0 A;  4HMX A;  1RZ0 A;  2GUJ A;  4IRA A;  3TGV A;  3VY2 A;  2P5Z X;  3HE1 A;  3ZOE A;  2HHZ A;  3F7E A;  4YBN A;  2PTF A;  2HQ7 A;  1XHN A;  2A2J A;  4HKH A;  1I0R A;  3SWJ A;  3U34 A;  5CHE C; 
#chains in the Genus database with same CATH homology
 3A6Q A;  1EJE A;  1I0S A;  3K88 A;  2OU5 A;  4N7R C;  1AXJ A;  3ZOG A;  1Y30 A;  2HTI A;  2E83 A;  3HMZ A;  3VY5 A;  3ZOH A;  3EC6 A;  3R5Y A;  3FGE A;  4XHY A;  1W3Q A;  2IG6 A;  5JAB A;  4Y9I A;  4XJ2 A;  1G77 A;  1DNL A;  1TY9 A;  1WLI A;  4R82 A;  2FG9 A;  2FHQ A;  3ZOC A;  3R5W A;  3DB0 A;  4HMT A;  5CHO A;  3DNH A;  2QEA A;  1G78 A;  1VL7 A;  1RZ1 A;  5ESC A;  2ASF A;  2ED4 A;  1USC A;  3BA3 A;  4HMS A;  3H96 A;  2R6V A;  3K87 A;  2I02 A;  4HMV A;  3AMF A;  3E4V A;  1W9A A;  1JNW A;  1WLK A;  2X1K A;  3DMB A;  3VYA A;  2FUR A;  3U35 A;  3RH7 A;  2GJG A;  2ECU A;  4F07 A;  1XXO A;  2VPA A;  3PFT A;  3AWH A;  2ECR A;  1G79 A;  3U5W A;  3BPK A;  3R5P A;  4YWN A;  1CI0 A;  1YOA A;  1T9M A;  1FLM A;  1USF A;  2IAB A;  1W3R A;  3KYF A;  3CP3 A;  4L82 A;  2HQ9 A;  1WGB A;  2D5M A;  3R5L A;  3ZOF A;  2I51 A;  1W3P A;  2D37 A;  2RE7 A;  3KYG A;  2QCK A;  4HMU A;  2NR4 A;  3A20 A;  2D36 A;  2OL5 A;  1W3O A;  3K86 A;  1RFE A;  2Q9K A;  2X1J A;  3FKH A;  3HY8 A;  4HX6 A;  3U0I A;  2HTD A;  3B5M A;  3NFW A;  2ARZ A;  3BNK A;  4HMW A;  3A6R A;  1G76 A;  1NRG A;  2RDE A;  2AQ6 A;  5BNC A;  2IML A;  2R0X A;  4Z85 A;  3IN6 A;  4QVB A;  3GAS A;  3ZOD A;  1YLN A;  1WV4 A;  3R5Z A;  3R5R A;  4ZKY A;  2D38 A;  3CB0 A;  4HMX A;  1RZ0 A;  4IRA A;  3TGV A;  3VY2 A;  3ZOE A;  2HHZ A;  3F7E A;  4YBN A;  2PTF A;  2HQ7 A;  1XHN A;  2A2J A;  1I0R A;  3SWJ A;  3U34 A;  5CHE C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...