3R8JA

Crystal structure of human soul protein (orthorhombic form)
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
180
structure length
180
Chain Sequence
AVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYNSPVKLLNRNNEVWLIQKN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Heme-binding protein 2
total genus 48
structure length 180
sequence length 180
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04832 SOUL SOUL heme-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A Regulatory factor, effector binding domain 3r8jA00
3Q5PA 1EXIA 5KAWA 4AYZB 5KAVA 1EXJA 1JYHA 3Q3DA 3B49A 5KAXA 3D6ZA 3Q5RA 3D71A 3IAOA 3Q5SA 5KCBA 1R8EA 1BOWA 3R8JA 2BOWA 3GK6A 5KAUA 1D5YA 3LURA 5GQQA 4AYZA 3R8KA 3Q1MA 3Q2YA 2HVAA 4B0YA 3D6YA 3E0HA 3D70A 5KATA 4A1MA 2KCUA 2GOVA
chains in the Genus database with same CATH superfamily
3Q5PA 1EXIA 5KAWA 4AYZB 5KAVA 1EXJA 1JYHA 3Q3DA 3B49A 5KAXA 3D6ZA 3Q5RA 3D71A 3IAOA 3Q5SA 5KCBA 1R8EA 1BOWA 3R8JA 2BOWA 3GK6A 5KAUA 1D5YA 3LURA 5GQQA 4AYZA 3R8KA 3Q1MA 3Q2YA 2HVAA 4B0YA 3D6YA 3E0HA 3D70A 5KATA 4A1MA 2KCUA 2GOVA
chains in the Genus database with same CATH topology
3Q5PA 1EXIA 5KAWA 4AYZB 5KAVA 1EXJA 1JYHA 3Q3DA 3B49A 5KAXA 3D6ZA 3Q5RA 3D71A 3IAOA 3Q5SA 5KCBA 1R8EA 1BOWA 3R8JA 2BOWA 3GK6A 5KAUA 1D5YA 3LURA 5GQQA 4AYZA 3R8KA 3Q1MA 3Q2YA 2HVAA 4B0YA 3D6YA 3E0HA 3D70A 5KATA 4A1MA 2KCUA 2GOVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q5P A;  1EXI A;  5KAW A;  4AYZ B;  5KAV A;  1EXJ A;  1JYH A;  3Q3D A;  3B49 A;  5KAX A;  3D6Z A;  3Q5R A;  3D71 A;  3IAO A;  3Q5S A;  5KCB A;  1R8E A;  1BOW A;  3R8J A;  2BOW A;  3GK6 A;  5KAU A;  1D5Y A;  3LUR A;  5GQQ A;  4AYZ A;  3R8K A;  3Q1M A;  3Q2Y A;  2HVA A;  4B0Y A;  3D6Y A;  3E0H A;  3D70 A;  5KAT A;  4A1M A;  2KCU A;  2GOV A; 
#chains in the Genus database with same CATH topology
 3Q5P A;  1EXI A;  5KAW A;  4AYZ B;  5KAV A;  1EXJ A;  1JYH A;  3Q3D A;  3B49 A;  5KAX A;  3D6Z A;  3Q5R A;  3D71 A;  3IAO A;  3Q5S A;  5KCB A;  1R8E A;  1BOW A;  3R8J A;  2BOW A;  3GK6 A;  5KAU A;  1D5Y A;  3LUR A;  5GQQ A;  4AYZ A;  3R8K A;  3Q1M A;  3Q2Y A;  2HVA A;  4B0Y A;  3D6Y A;  3E0H A;  3D70 A;  5KAT A;  4A1M A;  2KCU A;  2GOV A; 
#chains in the Genus database with same CATH homology
 3Q5P A;  1EXI A;  5KAW A;  4AYZ B;  5KAV A;  1EXJ A;  1JYH A;  3Q3D A;  3B49 A;  5KAX A;  3D6Z A;  3Q5R A;  3D71 A;  3IAO A;  3Q5S A;  5KCB A;  1R8E A;  1BOW A;  3R8J A;  2BOW A;  3GK6 A;  5KAU A;  1D5Y A;  3LUR A;  5GQQ A;  4AYZ A;  3R8K A;  3Q1M A;  3Q2Y A;  2HVA A;  4B0Y A;  3D6Y A;  3E0H A;  3D70 A;  5KAT A;  4A1M A;  2KCU A;  2GOV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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