3R8KA

Crystal structure of human soul protein (hexagonal form)
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
180
structure length
180
Chain Sequence
AVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYNSPVKLLNRNNEVWLIQKN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural changes in the BH3 domain of SOUL protein upon interaction with the anti-apoptotic protein Bcl-xL.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Heme-binding protein 2
total genus 40
structure length 180
sequence length 180
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04832 SOUL SOUL heme-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A Regulatory factor, effector binding domain 3r8kA00
3D71A 3E0HA 3R8JA 4AYZB 3D6ZA 3IAOA 5KCBA 5KAWA 3Q1MA 5KAVA 3LURA 3GK6A 5GQQA 2BOWA 3Q5RA 3Q5SA 5KAUA 1D5YA 1R8EA 1JYHA 1EXIA 3D6YA 2HVAA 1BOWA 3D70A 3Q5PA 3Q3DA 3R8KA 5KAXA 4A1MA 1EXJA 5KATA 4AYZA 3B49A 4B0YA 2GOVA 2KCUA 3Q2YA
chains in the Genus database with same CATH superfamily
3D71A 3E0HA 3R8JA 4AYZB 3D6ZA 3IAOA 5KCBA 5KAWA 3Q1MA 5KAVA 3LURA 3GK6A 5GQQA 2BOWA 3Q5RA 3Q5SA 5KAUA 1D5YA 1R8EA 1JYHA 1EXIA 3D6YA 2HVAA 1BOWA 3D70A 3Q5PA 3Q3DA 3R8KA 5KAXA 4A1MA 1EXJA 5KATA 4AYZA 3B49A 4B0YA 2GOVA 2KCUA 3Q2YA
chains in the Genus database with same CATH topology
3D71A 3E0HA 3R8JA 4AYZB 3D6ZA 3IAOA 5KCBA 5KAWA 3Q1MA 5KAVA 3LURA 3GK6A 5GQQA 2BOWA 3Q5RA 3Q5SA 5KAUA 1D5YA 1R8EA 1JYHA 1EXIA 3D6YA 2HVAA 1BOWA 3D70A 3Q5PA 3Q3DA 3R8KA 5KAXA 4A1MA 1EXJA 5KATA 4AYZA 3B49A 4B0YA 2GOVA 2KCUA 3Q2YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D71 A;  3E0H A;  3R8J A;  4AYZ B;  3D6Z A;  3IAO A;  5KCB A;  5KAW A;  3Q1M A;  5KAV A;  3LUR A;  3GK6 A;  5GQQ A;  2BOW A;  3Q5R A;  3Q5S A;  5KAU A;  1D5Y A;  1R8E A;  1JYH A;  1EXI A;  3D6Y A;  2HVA A;  1BOW A;  3D70 A;  3Q5P A;  3Q3D A;  3R8K A;  5KAX A;  4A1M A;  1EXJ A;  5KAT A;  4AYZ A;  3B49 A;  4B0Y A;  2GOV A;  2KCU A;  3Q2Y A; 
#chains in the Genus database with same CATH topology
 3D71 A;  3E0H A;  3R8J A;  4AYZ B;  3D6Z A;  3IAO A;  5KCB A;  5KAW A;  3Q1M A;  5KAV A;  3LUR A;  3GK6 A;  5GQQ A;  2BOW A;  3Q5R A;  3Q5S A;  5KAU A;  1D5Y A;  1R8E A;  1JYH A;  1EXI A;  3D6Y A;  2HVA A;  1BOW A;  3D70 A;  3Q5P A;  3Q3D A;  3R8K A;  5KAX A;  4A1M A;  1EXJ A;  5KAT A;  4AYZ A;  3B49 A;  4B0Y A;  2GOV A;  2KCU A;  3Q2Y A; 
#chains in the Genus database with same CATH homology
 3D71 A;  3E0H A;  3R8J A;  4AYZ B;  3D6Z A;  3IAO A;  5KCB A;  5KAW A;  3Q1M A;  5KAV A;  3LUR A;  3GK6 A;  5GQQ A;  2BOW A;  3Q5R A;  3Q5S A;  5KAU A;  1D5Y A;  1R8E A;  1JYH A;  1EXI A;  3D6Y A;  2HVA A;  1BOW A;  3D70 A;  3Q5P A;  3Q3D A;  3R8K A;  5KAX A;  4A1M A;  1EXJ A;  5KAT A;  4AYZ A;  3B49 A;  4B0Y A;  2GOV A;  2KCU A;  3Q2Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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