3RD7A

Crystal structure of acyl-coa thioesterase from mycobacterium avium
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
281
structure length
275
Chain Sequence
MISTLEDVLSLLDLQQIDDAAFVGTQPDTPNHHIIGSQVAAQALMAAGRTTPGRLAHSMHMYFLRRGDARQPIQYDVTPLRDGGTISSRRVTASQSGVVLFEALASFTIIADDVDWQQRMPDVAGPSAVHGLEDLLAPYAEEFQRPFTMRYLDAPPRVALDLSDPPPPRLRIWLRANGEVTDDPLVNSCVVAYLSALTLLECVMTTMRTTPVGPRLSALVDHTIWFHRAADFTDWLLFDQFSPSIVGRRGLATGTLYNRSGELVCIATQEGYFAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium avium
molecule keywords Acyl-CoA thioesterase
total genus 77
structure length 275
sequence length 281
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13622 4HBT_3 Thioesterase-like superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.129.90 Alpha Beta Roll Thiol Ester Dehydrase; Chain A Thiol Ester Dehydrase; Chain A 3rd7A00
4R9ZA 4QFWA 3RQBA 3BBJA 3RD7A 3CJYA 4R4UA 3U0AA
chains in the Genus database with same CATH superfamily
5DM5A 5BUXA 3LW3A 4W78A 4ZW0A 3AZ9A 1WLVA 4RV2B 3DP3A 3KG6A 5SZZA 3KV8A 5E1VA 3R3BA 5T06A 4NCPA 3KUVA 4RLWA 3R37A 3K67A 2HX5A 1SH8A 1MKBA 3LBEA 1PSUA 4I45A 3DP1A 3IR3A 3NWZA 4YBVA 3FRNA 1ZHGA 4K4CA 1Q4TA 1U1ZA 3P2SA 4RLJA 4RV2A 4W78B 4B0IA 3R36A 4ZV3A 4QD8A 2O5UA 3HRRA 3R3FA 5EGLA 3CJYA 1OHFA 3RD7A 4ZJBA 3R3DA 3U0AA 3D04A 4XY6A 5SZUA 3OMLA 3S6PA 1Q6WA 2B3MA 4B0CA 1IXLA 1T82A 1WLUA 2OV9A 4XY5A 3QOOA 5T02A 4ORDA 2W3XA 2EGJA 2EISA 3LWGA 2CWZA 1C8UA 3E1EA 2F3XA 2PZHA 1LO9A 4RLJB 4I82A 3KVIA 1WM6A 2PFCA 2OKIA 3KW1A 3KX7A 2VKZG 4R4UA 3P3FA 4RMMA 4ZRFA 5KKUA 1S9CA 4K00A 4LN9A 1Z54A 4MOBA 2H4UA 4K02A 4MZQA 5EO2A 2GVHA 1YOCA 4RLUB 3AZAA 5BYUA 3KVUA 3BBJA 3Q62A 3DOZA 3KVZA 2OAFA 5EO4A 3F5OA 3KUWA 3ED0A 3R3AA 1LO8A 3AZBA 4HZOA 1Z6BA 2DSLA 2F41A 1NJKA 3P2QA 3ESIA 2EGRA 2O6TA 3ZH7B 3D6LA 3HDUA 1S5UA 3BNVA 3LZ7A 3DP2A 2BI0A 4ZRBA 1PN4A 3D6XA 4AE8A 1SBKA 1VH9A 1J1YA 5BUWA 5BP3A 1TBUA 4GAKA 3E29A 3LMBA 4R9ZA 4RLUA 1YLIA 2Q78A 2UV8G 2FUJA 4I4JA 4MTUA 4QD9A 3HM0A 1Y7UA 2V1OA 2VZ8A 3SPSA 4E3EA 5EGJA 2CY9A 3ZH7A 4B0JA 3F1TA 4OOBA 2QQPA 1MKAA 4OOCA 3CF8A 4A0YA 3KG7A 3TEAA 3QY3A 5EP5A 3KH8A 3CF9A 4FFUA 3ZH5A 5BUYA 2EGIA 2NUJA 5HMBA 4H4GA 4IENA 4U3VA 5HWFA 1VI8A 1VH5A 3DKZA 4K4DA 4K4BA 1WN3A 3B7JA 4A0ZA 1Q4UA 2FS2A 3AZ8A 4QFWA 4CL6A 4QDAA 5KL9A 2PIMA 3B18A 1ZKIA 2OWNA 4A0XA 3BJKA 2OIWA 2XFLA 4M20A 4RLTB 4WNBB 3WEWA 1LO7A 4QDBA 4K49A 1Q4SA 2GLVA 3P3IA 5F6RA 3R34A 1VPMA 3KHPA 2CYEA 5HMCA 3KG8A 2GF6A 2F0XA 3KX8A 4KEHA 4A12A 2O6UA 2C2IA 2GLPA 3DP0A 4B0BA 2HLJA 2OKHA 5HD6A 3R35A 2QQ2A 4I83A 2GLLA 3R87A 5BP2A 2O6BA 2B6EA 3EL6A 3ZH6A 4AE7A 2PRXA 4RLTA 4WNBA 3EXZA 3KV7A 4GAHA 4KC5A 4HZPA 3HRQA 4B8UA 1IQ6A 2AV9A 3P2RA 1PN2A 5SZVA 3KG9A 3CK1A 5CPGA 5SZYA 2Q2BA 3E8PA 2GLMA 3RQBA 4MOCA 1SC0A 3DOYA 5HZ4A 3HMJG 2QWZA 3GEKA 4HZNA 2ESSA 2XEMA 3R3CA 4RLWB 3B7KA 3LBBA 3S4KA 2VZ9A 3R32A 5DIOA 4FQ9A 5EGKA 1BVQA 4QD7A 5T07A 2HBOA 4K4AA
chains in the Genus database with same CATH topology
2VZ8A 3KG6A 3ZH7A 2PFCA 5E1VA 2VKZG 4R4UA 5BP2A 5KKUA 4OOCA 3ZH6A 3EL6A 3KG7A 4LN9A 4KC5A 3ZH5A 3HRQA 3BBJA 4U3VA 3FRNA 3KG9A 4QFWA 3ZH7B 3RQBA 3HMJG 3HRRA 3B18A 3CJYA 1OHFA 3RD7A 3U0AA 2VZ9A 3S6PA 5BP3A 4R9ZA 2QQPA 2UV8G 3KG8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R9Z A;  4QFW A;  3RQB A;  3BBJ A;  3RD7 A;  3CJY A;  4R4U A;  3U0A A; 
#chains in the Genus database with same CATH topology
 5DM5 A;  5BUX A;  3LW3 A;  4W78 A;  4ZW0 A;  3AZ9 A;  1WLV A;  4RV2 B;  3DP3 A;  3KG6 A;  5SZZ A;  3KV8 A;  5E1V A;  3R3B A;  5T06 A;  4NCP A;  3KUV A;  4RLW A;  3R37 A;  3K67 A;  2HX5 A;  1SH8 A;  1MKB A;  3LBE A;  1PSU A;  4I45 A;  3DP1 A;  3IR3 A;  3NWZ A;  4YBV A;  3FRN A;  1ZHG A;  4K4C A;  1Q4T A;  1U1Z A;  3P2S A;  4RLJ A;  4RV2 A;  4W78 B;  4B0I A;  3R36 A;  4ZV3 A;  4QD8 A;  2O5U A;  3HRR A;  3R3F A;  5EGL A;  3CJY A;  1OHF A;  3RD7 A;  4ZJB A;  3R3D A;  3U0A A;  3D04 A;  4XY6 A;  5SZU A;  3OML A;  3S6P A;  1Q6W A;  2B3M A;  4B0C A;  1IXL A;  1T82 A;  1WLU A;  2OV9 A;  4XY5 A;  3QOO A;  5T02 A;  4ORD A;  2W3X A;  2EGJ A;  2EIS A;  3LWG A;  2CWZ A;  1C8U A;  3E1E A;  2F3X A;  2PZH A;  1LO9 A;  4RLJ B;  4I82 A;  3KVI A;  1WM6 A;  2PFC A;  2OKI A;  3KW1 A;  3KX7 A;  2VKZ G;  4R4U A;  3P3F A;  4RMM A;  4ZRF A;  5KKU A;  1S9C A;  4K00 A;  4LN9 A;  1Z54 A;  4MOB A;  2H4U A;  4K02 A;  4MZQ A;  5EO2 A;  2GVH A;  1YOC A;  4RLU B;  3AZA A;  5BYU A;  3KVU A;  3BBJ A;  3Q62 A;  3DOZ A;  3KVZ A;  2OAF A;  5EO4 A;  3F5O A;  3KUW A;  3ED0 A;  3R3A A;  1LO8 A;  3AZB A;  4HZO A;  1Z6B A;  2DSL A;  2F41 A;  1NJK A;  3P2Q A;  3ESI A;  2EGR A;  2O6T A;  3ZH7 B;  3D6L A;  3HDU A;  1S5U A;  3BNV A;  3LZ7 A;  3DP2 A;  2BI0 A;  4ZRB A;  1PN4 A;  3D6X A;  4AE8 A;  1SBK A;  1VH9 A;  1J1Y A;  5BUW A;  5BP3 A;  1TBU A;  4GAK A;  3E29 A;  3LMB A;  4R9Z A;  4RLU A;  1YLI A;  2Q78 A;  2UV8 G;  2FUJ A;  4I4J A;  4MTU A;  4QD9 A;  3HM0 A;  1Y7U A;  2V1O A;  2VZ8 A;  3SPS A;  4E3E A;  5EGJ A;  2CY9 A;  3ZH7 A;  4B0J A;  3F1T A;  4OOB A;  2QQP A;  1MKA A;  4OOC A;  3CF8 A;  4A0Y A;  3KG7 A;  3TEA A;  3QY3 A;  5EP5 A;  3KH8 A;  3CF9 A;  4FFU A;  3ZH5 A;  5BUY A;  2EGI A;  2NUJ A;  5HMB A;  4H4G A;  4IEN A;  4U3V A;  5HWF A;  1VI8 A;  1VH5 A;  3DKZ A;  4K4D A;  4K4B A;  1WN3 A;  3B7J A;  4A0Z A;  1Q4U A;  2FS2 A;  3AZ8 A;  4QFW A;  4CL6 A;  4QDA A;  5KL9 A;  2PIM A;  3B18 A;  1ZKI A;  2OWN A;  4A0X A;  3BJK A;  2OIW A;  2XFL A;  4M20 A;  4RLT B;  4WNB B;  3WEW A;  1LO7 A;  4QDB A;  4K49 A;  1Q4S A;  2GLV A;  3P3I A;  5F6R A;  3R34 A;  1VPM A;  3KHP A;  2CYE A;  5HMC A;  3KG8 A;  2GF6 A;  2F0X A;  3KX8 A;  4KEH A;  4A12 A;  2O6U A;  2C2I A;  2GLP A;  3DP0 A;  4B0B A;  2HLJ A;  2OKH A;  5HD6 A;  3R35 A;  2QQ2 A;  4I83 A;  2GLL A;  3R87 A;  5BP2 A;  2O6B A;  2B6E A;  3EL6 A;  3ZH6 A;  4AE7 A;  2PRX A;  4RLT A;  4WNB A;  3EXZ A;  3KV7 A;  4GAH A;  4KC5 A;  4HZP A;  3HRQ A;  4B8U A;  1IQ6 A;  2AV9 A;  3P2R A;  1PN2 A;  5SZV A;  3KG9 A;  3CK1 A;  5CPG A;  5SZY A;  2Q2B A;  3E8P A;  2GLM A;  3RQB A;  4MOC A;  1SC0 A;  3DOY A;  5HZ4 A;  3HMJ G;  2QWZ A;  3GEK A;  4HZN A;  2ESS A;  2XEM A;  3R3C A;  4RLW B;  3B7K A;  3LBB A;  3S4K A;  2VZ9 A;  3R32 A;  5DIO A;  4FQ9 A;  5EGK A;  1BVQ A;  4QD7 A;  5T07 A;  2HBO A;  4K4A A; 
#chains in the Genus database with same CATH homology
 2VZ8 A;  3KG6 A;  3ZH7 A;  2PFC A;  5E1V A;  2VKZ G;  4R4U A;  5BP2 A;  5KKU A;  4OOC A;  3ZH6 A;  3EL6 A;  3KG7 A;  4LN9 A;  4KC5 A;  3ZH5 A;  3HRQ A;  3BBJ A;  4U3V A;  3FRN A;  3KG9 A;  4QFW A;  3ZH7 B;  3RQB A;  3HMJ G;  3HRR A;  3B18 A;  3CJY A;  1OHF A;  3RD7 A;  3U0A A;  2VZ9 A;  3S6P A;  5BP3 A;  4R9Z A;  2QQP A;  2UV8 G;  3KG8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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