3RL5A

Rat metallophosphodiesterase mpped2 h67r mutant
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
281
structure length
279
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTRSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Metallophosphoesterase MPPED2
publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 91
structure length 279
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl5A00
1W24A 3KBPA 4LACC 4JA7A 3QFMA 5C1VA 3C5WC 2HYOA 2HY1A 1AUIA 4UT3B 4TUIA 1OIEA 4H1SA 4IYPC 4DHLA 5JPFA 1UF3A 5EQVA 2R17A 1JK7A 4DSYA 4DT2A 2WDCA 3GVEA 3P71C 3RL4A 1S3NA 3H68A 4FCXA 1WARA 4KBPA 3DSCA 3THOB 3CK2A 3C9FA 2O8AA 1SU1A 4Q7FA 2ZBMA 1MF8A 3H60A 2BQ8X 3RL5A 2CV9A 1HP1A 3JYFA 3T1IA 4HD0A 4B2OA 4H2BA 5JPEA 1FJMA 3E7AA 4NZVA 1II7A 4O43A 3RQZA 3DSDA 2JOGA 4V0WA 3EGHA 3ZU0A 1U32A 1Z2XA 3RL3A 1M63A 3QFOA 4MP0A 3PSNA 4ORCA 2Z1AA 3IVDA 4LU9A 1HPUA 2HYPA 3H69A 4YKEA 3ICFA 4I5NC 1OIDA 5F3WA 3LL8A 1NNWA 3E7BA 3DW8C 2WDEA 3HVQA 3QFKA 4KKZA 1OI8A 1T71A 3N5UA 2AHDA 4MOYA 2NXFA 3TGHA 3H62B 2BDXA 2O8GA 4I5LC 2KKNA 3AV0A 3FGAC 1S3MA 4UT2A 4TUGA 4O5GA 4J6OA 1HO5A 3V4YA 5INBA 3QFNA 5J28A 1XM7A 2NYLC 3PSOA 1T70A 3H66A 1KBPA 4O4KA 5JJTA 1S3LA 1V73A 2XMOA 3H67A 1IT6A 3QG5C 2WDFA 1QFCA 5GTUA 4ORBA 5B8IA 4O24A 3H64A 1UTEA 1XZWA 1TCOA 1QHWA 4IL1A 3IB7A 4JA9A 2YVTA 1Z2WA 4UWQA 2QJCA 4UT3A 2NYMC 2QFPA 1S95A 2IE4C 1G5BA 4FBQA 4XPNA 2USHA 3AUZA 4H2FA 3THNA 2QFRA 2WDDA 4OR9A 3EGGA 4M0VA 4MOVA 4FBKA 4ZX2A 3K7WC 2GJUA 4F0ZA 5DNYA 2A22A 4G9JA 2DFJA 2Z72A 2Q8UA 4FBWA 4ZVZA 5IOHA 1WAO1 5HPEA 4ORAA 3IVEA 4H1YP 3H61A 1USHA 2IE3C 1S70A 4LTYA 2IAEC 2BCDA 3IB8A 4H2GA 3ZTVA 4V0VA 2P6BA 2NPPC 2Z06A 4WWLA 4V0XA 4H2IA 3H63A 1S8EA 3K7VC
chains in the Genus database with same CATH superfamily
3D03A 1W24A 3KBPA 4LACC 4JA7A 3QFMA 5C1VA 2ZO9B 3C5WC 2HYOA 2HY1A 1AUIA 4UT3B 4TUIA 1OIEA 4H1SA 4IYPC 4DHLA 5JPFA 1UF3A 5EQVA 2R17A 1JK7A 4DSYA 4DT2A 2WDCA 3GVEA 3P71C 3RL4A 1S3NA 3H68A 4FCXA 1WARA 2YEQA 4KBPA 3DSCA 3THOB 3CK2A 3C9FA 2O8AA 1SU1A 2ZOAA 4Q7FA 2ZBMA 1MF8A 3H60A 2BQ8X 3RL5A 2CV9A 1HP1A 3JYFA 3T1IA 4HD0A 4B2OA 4H2BA 5JPEA 1FJMA 3E7AA 4NZVA 2DXLA 1II7A 4O43A 3RQZA 3DSDA 2JOGA 4V0WA 3EGHA 3ZU0A 1U32A 1Z2XA 3RL3A 1M63A 3QFOA 4MP0A 3PSNA 4ORCA 2Z1AA 3IVDA 4LU9A 1HPUA 2HYPA 3H69A 4YKEA 3ICFA 4I5NC 1OIDA 5F3WA 3LL8A 1NNWA 3E7BA 3DW8C 2WDEA 3HVQA 3QFKA 4KKZA 1OI8A 1T71A 3N5UA 2AHDA 4MOYA 2NXFA 3TGHA 3H62B 2BDXA 2O8GA 4I5LC 2KKNA 3AV0A 3FGAC 1S3MA 4UT2A 4TUGA 4O5GA 4J6OA 1HO5A 3V4YA 5INBA 3QFNA 5J28A 1XM7A 2NYLC 3PSOA 1T70A 3H66A 1KBPA 4O4KA 5JJTA 1S3LA 1V73A 2XMOA 3H67A 1IT6A 3QG5C 2WDFA 1QFCA 5GTUA 4ORBA 5B8IA 4O24A 3H64A 1UTEA 1XZWA 1TCOA 1QHWA 4IL1A 3IB7A 4JA9A 2YVTA 1Z2WA 4UWQA 2QJCA 4UT3A 2NYMC 2DXNA 2QFPA 1S95A 2IE4C 1G5BA 4FBQA 4XPNA 2USHA 3AUZA 4H2FA 3THNA 2QFRA 2WDDA 4OR9A 3EGGA 4M0VA 4MOVA 4FBKA 4ZX2A 3K7WC 2GJUA 4F0ZA 5DNYA 2A22A 4G9JA 2DFJA 2Z72A 2Q8UA 4FBWA 4ZVZA 5IOHA 1WAO1 5HPEA 3FLOA 4ORAA 3IVEA 4H1YP 3H61A 1USHA 2IE3C 1S70A 4LTYA 2IAEC 2BCDA 3IB8A 4H2GA 3ZTVA 3E0JA 4V0VA 2P6BA 2NPPC 2Z06A 4WWLA 4V0XA 4H2IA 3H63A 1S8EA 3K7VC
chains in the Genus database with same CATH topology
3D03A 1W24A 3KBPA 4LACC 4JA7A 3QFMA 5C1VA 2ZO9B 3C5WC 2HYOA 2HY1A 1AUIA 4UT3B 4TUIA 1OIEA 4H1SA 4IYPC 4DHLA 5JPFA 1UF3A 5EQVA 2R17A 1JK7A 4DSYA 4DT2A 2WDCA 3GVEA 3P71C 3RL4A 1S3NA 3H68A 4FCXA 1WARA 2YEQA 4KBPA 3DSCA 3THOB 3CK2A 3C9FA 2O8AA 1SU1A 2ZOAA 4Q7FA 2ZBMA 1MF8A 3H60A 2BQ8X 3RL5A 2CV9A 1HP1A 3JYFA 3T1IA 4HD0A 4B2OA 4H2BA 5JPEA 1FJMA 3E7AA 4NZVA 2DXLA 1II7A 4O43A 3RQZA 3DSDA 2JOGA 4V0WA 3EGHA 3ZU0A 1U32A 1Z2XA 3RL3A 1M63A 3QFOA 4MP0A 3PSNA 4ORCA 2Z1AA 3IVDA 4LU9A 1HPUA 2HYPA 3H69A 4YKEA 3ICFA 4I5NC 1OIDA 5F3WA 3LL8A 1NNWA 3E7BA 3DW8C 2WDEA 3HVQA 3QFKA 4KKZA 1OI8A 1T71A 3N5UA 2AHDA 4MOYA 2NXFA 3TGHA 3H62B 2BDXA 2O8GA 4I5LC 2KKNA 3AV0A 3FGAC 1S3MA 4UT2A 4TUGA 4O5GA 4J6OA 1HO5A 3V4YA 5INBA 3QFNA 5J28A 1XM7A 2NYLC 3PSOA 1T70A 3H66A 1KBPA 4O4KA 5JJTA 1S3LA 1V73A 2XMOA 3H67A 1IT6A 3QG5C 2WDFA 1QFCA 5GTUA 4ORBA 5B8IA 4O24A 3H64A 1UTEA 1XZWA 1TCOA 1QHWA 4IL1A 3IB7A 4JA9A 2YVTA 1Z2WA 4UWQA 2QJCA 4UT3A 2NYMC 2DXNA 2QFPA 1S95A 2IE4C 1G5BA 4FBQA 4XPNA 2USHA 3AUZA 4H2FA 3THNA 2QFRA 2WDDA 4OR9A 3EGGA 4M0VA 4MOVA 4FBKA 4ZX2A 3K7WC 2GJUA 4F0ZA 5DNYA 2A22A 4G9JA 2DFJA 2Z72A 2Q8UA 4FBWA 4ZVZA 5IOHA 1WAO1 5HPEA 3FLOA 4ORAA 3IVEA 4H1YP 3H61A 1USHA 2IE3C 1S70A 4LTYA 2IAEC 2BCDA 3IB8A 4H2GA 3ZTVA 3E0JA 4V0VA 2P6BA 2NPPC 2Z06A 4WWLA 4V0XA 4H2IA 3H63A 1S8EA 3K7VC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1W24 A;  3KBP A;  4LAC C;  4JA7 A;  3QFM A;  5C1V A;  3C5W C;  2HYO A;  2HY1 A;  1AUI A;  4UT3 B;  4TUI A;  1OIE A;  4H1S A;  4IYP C;  4DHL A;  5JPF A;  1UF3 A;  5EQV A;  2R17 A;  1JK7 A;  4DSY A;  4DT2 A;  2WDC A;  3GVE A;  3P71 C;  3RL4 A;  1S3N A;  3H68 A;  4FCX A;  1WAR A;  4KBP A;  3DSC A;  3THO B;  3CK2 A;  3C9F A;  2O8A A;  1SU1 A;  4Q7F A;  2ZBM A;  1MF8 A;  3H60 A;  2BQ8 X;  3RL5 A;  2CV9 A;  1HP1 A;  3JYF A;  3T1I A;  4HD0 A;  4B2O A;  4H2B A;  5JPE A;  1FJM A;  3E7A A;  4NZV A;  1II7 A;  4O43 A;  3RQZ A;  3DSD A;  2JOG A;  4V0W A;  3EGH A;  3ZU0 A;  1U32 A;  1Z2X A;  3RL3 A;  1M63 A;  3QFO A;  4MP0 A;  3PSN A;  4ORC A;  2Z1A A;  3IVD A;  4LU9 A;  1HPU A;  2HYP A;  3H69 A;  4YKE A;  3ICF A;  4I5N C;  1OID A;  5F3W A;  3LL8 A;  1NNW A;  3E7B A;  3DW8 C;  2WDE A;  3HVQ A;  3QFK A;  4KKZ A;  1OI8 A;  1T71 A;  3N5U A;  2AHD A;  4MOY A;  2NXF A;  3TGH A;  3H62 B;  2BDX A;  2O8G A;  4I5L C;  2KKN A;  3AV0 A;  3FGA C;  1S3M A;  4UT2 A;  4TUG A;  4O5G A;  4J6O A;  1HO5 A;  3V4Y A;  5INB A;  3QFN A;  5J28 A;  1XM7 A;  2NYL C;  3PSO A;  1T70 A;  3H66 A;  1KBP A;  4O4K A;  5JJT A;  1S3L A;  1V73 A;  2XMO A;  3H67 A;  1IT6 A;  3QG5 C;  2WDF A;  1QFC A;  5GTU A;  4ORB A;  5B8I A;  4O24 A;  3H64 A;  1UTE A;  1XZW A;  1TCO A;  1QHW A;  4IL1 A;  3IB7 A;  4JA9 A;  2YVT A;  1Z2W A;  4UWQ A;  2QJC A;  4UT3 A;  2NYM C;  2QFP A;  1S95 A;  2IE4 C;  1G5B A;  4FBQ A;  4XPN A;  2USH A;  3AUZ A;  4H2F A;  3THN A;  2QFR A;  2WDD A;  4OR9 A;  3EGG A;  4M0V A;  4MOV A;  4FBK A;  4ZX2 A;  3K7W C;  2GJU A;  4F0Z A;  5DNY A;  2A22 A;  4G9J A;  2DFJ A;  2Z72 A;  2Q8U A;  4FBW A;  4ZVZ A;  5IOH A;  1WAO 1;  5HPE A;  4ORA A;  3IVE A;  4H1Y P;  3H61 A;  1USH A;  2IE3 C;  1S70 A;  4LTY A;  2IAE C;  2BCD A;  3IB8 A;  4H2G A;  3ZTV A;  4V0V A;  2P6B A;  2NPP C;  2Z06 A;  4WWL A;  4V0X A;  4H2I A;  3H63 A;  1S8E A;  3K7V C; 
#chains in the Genus database with same CATH topology
 3D03 A;  1W24 A;  3KBP A;  4LAC C;  4JA7 A;  3QFM A;  5C1V A;  2ZO9 B;  3C5W C;  2HYO A;  2HY1 A;  1AUI A;  4UT3 B;  4TUI A;  1OIE A;  4H1S A;  4IYP C;  4DHL A;  5JPF A;  1UF3 A;  5EQV A;  2R17 A;  1JK7 A;  4DSY A;  4DT2 A;  2WDC A;  3GVE A;  3P71 C;  3RL4 A;  1S3N A;  3H68 A;  4FCX A;  1WAR A;  2YEQ A;  4KBP A;  3DSC A;  3THO B;  3CK2 A;  3C9F A;  2O8A A;  1SU1 A;  2ZOA A;  4Q7F A;  2ZBM A;  1MF8 A;  3H60 A;  2BQ8 X;  3RL5 A;  2CV9 A;  1HP1 A;  3JYF A;  3T1I A;  4HD0 A;  4B2O A;  4H2B A;  5JPE A;  1FJM A;  3E7A A;  4NZV A;  2DXL A;  1II7 A;  4O43 A;  3RQZ A;  3DSD A;  2JOG A;  4V0W A;  3EGH A;  3ZU0 A;  1U32 A;  1Z2X A;  3RL3 A;  1M63 A;  3QFO A;  4MP0 A;  3PSN A;  4ORC A;  2Z1A A;  3IVD A;  4LU9 A;  1HPU A;  2HYP A;  3H69 A;  4YKE A;  3ICF A;  4I5N C;  1OID A;  5F3W A;  3LL8 A;  1NNW A;  3E7B A;  3DW8 C;  2WDE A;  3HVQ A;  3QFK A;  4KKZ A;  1OI8 A;  1T71 A;  3N5U A;  2AHD A;  4MOY A;  2NXF A;  3TGH A;  3H62 B;  2BDX A;  2O8G A;  4I5L C;  2KKN A;  3AV0 A;  3FGA C;  1S3M A;  4UT2 A;  4TUG A;  4O5G A;  4J6O A;  1HO5 A;  3V4Y A;  5INB A;  3QFN A;  5J28 A;  1XM7 A;  2NYL C;  3PSO A;  1T70 A;  3H66 A;  1KBP A;  4O4K A;  5JJT A;  1S3L A;  1V73 A;  2XMO A;  3H67 A;  1IT6 A;  3QG5 C;  2WDF A;  1QFC A;  5GTU A;  4ORB A;  5B8I A;  4O24 A;  3H64 A;  1UTE A;  1XZW A;  1TCO A;  1QHW A;  4IL1 A;  3IB7 A;  4JA9 A;  2YVT A;  1Z2W A;  4UWQ A;  2QJC A;  4UT3 A;  2NYM C;  2DXN A;  2QFP A;  1S95 A;  2IE4 C;  1G5B A;  4FBQ A;  4XPN A;  2USH A;  3AUZ A;  4H2F A;  3THN A;  2QFR A;  2WDD A;  4OR9 A;  3EGG A;  4M0V A;  4MOV A;  4FBK A;  4ZX2 A;  3K7W C;  2GJU A;  4F0Z A;  5DNY A;  2A22 A;  4G9J A;  2DFJ A;  2Z72 A;  2Q8U A;  4FBW A;  4ZVZ A;  5IOH A;  1WAO 1;  5HPE A;  3FLO A;  4ORA A;  3IVE A;  4H1Y P;  3H61 A;  1USH A;  2IE3 C;  1S70 A;  4LTY A;  2IAE C;  2BCD A;  3IB8 A;  4H2G A;  3ZTV A;  3E0J A;  4V0V A;  2P6B A;  2NPP C;  2Z06 A;  4WWL A;  4V0X A;  4H2I A;  3H63 A;  1S8E A;  3K7V C; 
#chains in the Genus database with same CATH homology
 3D03 A;  1W24 A;  3KBP A;  4LAC C;  4JA7 A;  3QFM A;  5C1V A;  2ZO9 B;  3C5W C;  2HYO A;  2HY1 A;  1AUI A;  4UT3 B;  4TUI A;  1OIE A;  4H1S A;  4IYP C;  4DHL A;  5JPF A;  1UF3 A;  5EQV A;  2R17 A;  1JK7 A;  4DSY A;  4DT2 A;  2WDC A;  3GVE A;  3P71 C;  3RL4 A;  1S3N A;  3H68 A;  4FCX A;  1WAR A;  2YEQ A;  4KBP A;  3DSC A;  3THO B;  3CK2 A;  3C9F A;  2O8A A;  1SU1 A;  2ZOA A;  4Q7F A;  2ZBM A;  1MF8 A;  3H60 A;  2BQ8 X;  3RL5 A;  2CV9 A;  1HP1 A;  3JYF A;  3T1I A;  4HD0 A;  4B2O A;  4H2B A;  5JPE A;  1FJM A;  3E7A A;  4NZV A;  2DXL A;  1II7 A;  4O43 A;  3RQZ A;  3DSD A;  2JOG A;  4V0W A;  3EGH A;  3ZU0 A;  1U32 A;  1Z2X A;  3RL3 A;  1M63 A;  3QFO A;  4MP0 A;  3PSN A;  4ORC A;  2Z1A A;  3IVD A;  4LU9 A;  1HPU A;  2HYP A;  3H69 A;  4YKE A;  3ICF A;  4I5N C;  1OID A;  5F3W A;  3LL8 A;  1NNW A;  3E7B A;  3DW8 C;  2WDE A;  3HVQ A;  3QFK A;  4KKZ A;  1OI8 A;  1T71 A;  3N5U A;  2AHD A;  4MOY A;  2NXF A;  3TGH A;  3H62 B;  2BDX A;  2O8G A;  4I5L C;  2KKN A;  3AV0 A;  3FGA C;  1S3M A;  4UT2 A;  4TUG A;  4O5G A;  4J6O A;  1HO5 A;  3V4Y A;  5INB A;  3QFN A;  5J28 A;  1XM7 A;  2NYL C;  3PSO A;  1T70 A;  3H66 A;  1KBP A;  4O4K A;  5JJT A;  1S3L A;  1V73 A;  2XMO A;  3H67 A;  1IT6 A;  3QG5 C;  2WDF A;  1QFC A;  5GTU A;  4ORB A;  5B8I A;  4O24 A;  3H64 A;  1UTE A;  1XZW A;  1TCO A;  1QHW A;  4IL1 A;  3IB7 A;  4JA9 A;  2YVT A;  1Z2W A;  4UWQ A;  2QJC A;  4UT3 A;  2NYM C;  2DXN A;  2QFP A;  1S95 A;  2IE4 C;  1G5B A;  4FBQ A;  4XPN A;  2USH A;  3AUZ A;  4H2F A;  3THN A;  2QFR A;  2WDD A;  4OR9 A;  3EGG A;  4M0V A;  4MOV A;  4FBK A;  4ZX2 A;  3K7W C;  2GJU A;  4F0Z A;  5DNY A;  2A22 A;  4G9J A;  2DFJ A;  2Z72 A;  2Q8U A;  4FBW A;  4ZVZ A;  5IOH A;  1WAO 1;  5HPE A;  3FLO A;  4ORA A;  3IVE A;  4H1Y P;  3H61 A;  1USH A;  2IE3 C;  1S70 A;  4LTY A;  2IAE C;  2BCD A;  3IB8 A;  4H2G A;  3ZTV A;  3E0J A;  4V0V A;  2P6B A;  2NPP C;  2Z06 A;  4WWL A;  4V0X A;  4H2I A;  3H63 A;  1S8E A;  3K7V C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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