3RL5A

Rat metallophosphodiesterase mpped2 h67r mutant
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
281
structure length
279
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTRSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Metallophosphoesterase MPPED2
total genus 91
structure length 279
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl5A00
3P71C 4I5NC 2P6BA 1Z2XA 3K7WC 1S3NA 2ZBMA 1IT6A 4XPNA 4KKZA 4MOVA 3RL4A 4LACC 1WAO1 4H2FA 1XM7A 4H1YP 4UT3B 2NYLC 2Z1AA 4IYPC 3V4YA 2Z06A 3HVQA 4I5LC 4B2OA 4DT2A 2O8GA 2BCDA 4HD0A 3H66A 2WDCA 1OIEA 4ZX2A 3JYFA 1Z2WA 4F0ZA 1UF3A 4ORCA 5F3WA 3THOB 3QFNA 4TUIA 3H64A 1SU1A 3H60A 1UTEA 4V0WA 3IB7A 4MP0A 1USHA 5JPFA 1G5BA 3H68A 3N5UA 4FBQA 3PSNA 5DNYA 4O24A 4O43A 3LL8A 4V0XA 3DW8C 2QFRA 4Q7FA 4ORAA 3QFMA 3ZTVA 2QJCA 3H61A 3RQZA 2AHDA 2DFJA 5HPEA 1KBPA 3H62B 4WWLA 1T70A 2JOGA 2NXFA 2BDXA 3QFKA 4MOYA 4TUGA 4G9JA 1S3MA 4V0VA 4LU9A 2HY1A 5B8IA 4KBPA 4J6OA 1M63A 2IE3C 2HYOA 1S3LA 4YKEA 1OIDA 1NNWA 2HYPA 3H63A 1S8EA 3IB8A 4OR9A 2A22A 4ZVZA 1U32A 1JK7A 1S95A 3EGHA 4NZVA 4IL1A 4FBKA 4H2BA 2USHA 1TCOA 4LTYA 2BQ8X 3AUZA 2IAEC 3DSCA 5IOHA 4UT3A 4FCXA 5EQVA 3AV0A 1QFCA 3QFOA 5J28A 2R17A 1HPUA 4H2IA 1II7A 3C9FA 3QG5C 5INBA 2GJUA 4UT2A 4H2GA 1XZWA 3C5WC 4O4KA 2NPPC 1WARA 3E7AA 3DSDA 3IVDA 3FGAC 3CK2A 1OI8A 2WDDA 2IE4C 4O5GA 4DSYA 2NYMC 2Q8UA 3H69A 3RL3A 3EGGA 2XMOA 3H67A 3PSOA 4ORBA 4FBWA 1V73A 3KBPA 3RL5A 2Z72A 1HP1A 1W24A 4UWQA 4M0VA 2O8AA 1FJMA 3ICFA 5C1VA 3E7BA 4JA9A 3K7VC 2WDEA 3IVEA 1S70A 3ZU0A 2KKNA 1AUIA 2WDFA 5JJTA 1MF8A 3THNA 3T1IA 3GVEA 1HO5A 3TGHA 5JPEA 2QFPA 4H1SA 4JA7A 4DHLA 1T71A 2CV9A 2YVTA 1QHWA 5GTUA
chains in the Genus database with same CATH superfamily
3P71C 4I5NC 2P6BA 1Z2XA 3K7WC 1S3NA 2ZBMA 1IT6A 2ZO9B 4XPNA 4KKZA 4MOVA 3RL4A 4LACC 1WAO1 3D03A 1XM7A 4H2FA 4H1YP 4UT3B 2NYLC 2Z1AA 4IYPC 3V4YA 2Z06A 3HVQA 4I5LC 4B2OA 4DT2A 2O8GA 2BCDA 4HD0A 2ZOAA 3H66A 2WDCA 1OIEA 4ZX2A 3JYFA 1Z2WA 4F0ZA 1UF3A 4ORCA 5F3WA 3THOB 2DXNA 3QFNA 4TUIA 3H64A 1SU1A 3H60A 1UTEA 4V0WA 3IB7A 4MP0A 1USHA 5JPFA 1G5BA 3H68A 3N5UA 4FBQA 3PSNA 5DNYA 4O24A 4O43A 3LL8A 4V0XA 3DW8C 2QFRA 4Q7FA 4ORAA 3QFMA 2YEQA 3ZTVA 2QJCA 3H61A 3RQZA 2AHDA 2DFJA 5HPEA 1KBPA 3H62B 4WWLA 1T70A 2JOGA 2NXFA 2BDXA 3QFKA 4MOYA 4TUGA 4G9JA 1S3MA 4V0VA 4LU9A 2HY1A 5B8IA 4KBPA 4J6OA 1M63A 2IE3C 2HYOA 1S3LA 4YKEA 1OIDA 1NNWA 2HYPA 3H63A 1S8EA 3IB8A 4OR9A 2A22A 4ZVZA 1U32A 1JK7A 1S95A 3EGHA 4NZVA 4IL1A 4FBKA 4H2BA 2USHA 1TCOA 4LTYA 2BQ8X 3AUZA 2IAEC 3DSCA 5IOHA 4UT3A 4FCXA 5EQVA 3AV0A 1QFCA 3QFOA 5J28A 2R17A 1HPUA 4H2IA 1II7A 3C9FA 3QG5C 5INBA 2GJUA 4UT2A 4H2GA 1XZWA 3C5WC 4O4KA 2NPPC 1WARA 3E7AA 3DSDA 3IVDA 3FGAC 3CK2A 1OI8A 2WDDA 2IE4C 4O5GA 4DSYA 2NYMC 2Q8UA 3H69A 3RL3A 3EGGA 2XMOA 3H67A 3PSOA 4ORBA 4FBWA 1V73A 3KBPA 3RL5A 2Z72A 1HP1A 1W24A 4UWQA 4M0VA 2O8AA 1FJMA 3ICFA 5C1VA 3E7BA 4JA9A 3K7VC 2WDEA 3IVEA 1S70A 2DXLA 3ZU0A 2KKNA 1AUIA 2WDFA 5JJTA 1MF8A 3FLOA 3THNA 3T1IA 3GVEA 1HO5A 3TGHA 5JPEA 2QFPA 4H1SA 4JA7A 4DHLA 1T71A 2CV9A 2YVTA 1QHWA 5GTUA 3E0JA
chains in the Genus database with same CATH topology
3P71C 4I5NC 2P6BA 1Z2XA 3K7WC 1S3NA 2ZBMA 1IT6A 2ZO9B 4XPNA 4KKZA 4MOVA 3RL4A 4LACC 1WAO1 3D03A 1XM7A 4H2FA 4H1YP 4UT3B 2NYLC 2Z1AA 4IYPC 3V4YA 2Z06A 3HVQA 4I5LC 4B2OA 4DT2A 2O8GA 2BCDA 4HD0A 2ZOAA 3H66A 2WDCA 1OIEA 4ZX2A 3JYFA 1Z2WA 4F0ZA 1UF3A 4ORCA 5F3WA 3THOB 2DXNA 3QFNA 4TUIA 3H64A 1SU1A 3H60A 1UTEA 4V0WA 3IB7A 4MP0A 1USHA 5JPFA 1G5BA 3H68A 3N5UA 4FBQA 3PSNA 5DNYA 4O24A 4O43A 3LL8A 4V0XA 3DW8C 2QFRA 4Q7FA 4ORAA 3QFMA 2YEQA 3ZTVA 2QJCA 3H61A 3RQZA 2AHDA 2DFJA 5HPEA 1KBPA 3H62B 4WWLA 1T70A 2JOGA 2NXFA 2BDXA 3QFKA 4MOYA 4TUGA 4G9JA 1S3MA 4V0VA 4LU9A 2HY1A 5B8IA 4KBPA 4J6OA 1M63A 2IE3C 2HYOA 1S3LA 4YKEA 1OIDA 1NNWA 2HYPA 3H63A 1S8EA 3IB8A 4OR9A 2A22A 4ZVZA 1U32A 1JK7A 1S95A 3EGHA 4NZVA 4IL1A 4FBKA 4H2BA 2USHA 1TCOA 4LTYA 2BQ8X 3AUZA 2IAEC 3DSCA 5IOHA 4UT3A 4FCXA 5EQVA 3AV0A 1QFCA 3QFOA 5J28A 2R17A 1HPUA 4H2IA 1II7A 3C9FA 3QG5C 5INBA 2GJUA 4UT2A 4H2GA 1XZWA 3C5WC 4O4KA 2NPPC 1WARA 3E7AA 3DSDA 3IVDA 3FGAC 3CK2A 1OI8A 2WDDA 2IE4C 4O5GA 4DSYA 2NYMC 2Q8UA 3H69A 3RL3A 3EGGA 2XMOA 3H67A 3PSOA 4ORBA 4FBWA 1V73A 3KBPA 3RL5A 2Z72A 1HP1A 1W24A 4UWQA 4M0VA 2O8AA 1FJMA 3ICFA 5C1VA 3E7BA 4JA9A 3K7VC 2WDEA 3IVEA 1S70A 2DXLA 3ZU0A 2KKNA 1AUIA 2WDFA 5JJTA 1MF8A 3FLOA 3THNA 3T1IA 3GVEA 1HO5A 3TGHA 5JPEA 2QFPA 4H1SA 4JA7A 4DHLA 1T71A 2CV9A 2YVTA 1QHWA 5GTUA 3E0JA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3P71 C;  4I5N C;  2P6B A;  1Z2X A;  3K7W C;  1S3N A;  2ZBM A;  1IT6 A;  4XPN A;  4KKZ A;  4MOV A;  3RL4 A;  4LAC C;  1WAO 1;  4H2F A;  1XM7 A;  4H1Y P;  4UT3 B;  2NYL C;  2Z1A A;  4IYP C;  3V4Y A;  2Z06 A;  3HVQ A;  4I5L C;  4B2O A;  4DT2 A;  2O8G A;  2BCD A;  4HD0 A;  3H66 A;  2WDC A;  1OIE A;  4ZX2 A;  3JYF A;  1Z2W A;  4F0Z A;  1UF3 A;  4ORC A;  5F3W A;  3THO B;  3QFN A;  4TUI A;  3H64 A;  1SU1 A;  3H60 A;  1UTE A;  4V0W A;  3IB7 A;  4MP0 A;  1USH A;  5JPF A;  1G5B A;  3H68 A;  3N5U A;  4FBQ A;  3PSN A;  5DNY A;  4O24 A;  4O43 A;  3LL8 A;  4V0X A;  3DW8 C;  2QFR A;  4Q7F A;  4ORA A;  3QFM A;  3ZTV A;  2QJC A;  3H61 A;  3RQZ A;  2AHD A;  2DFJ A;  5HPE A;  1KBP A;  3H62 B;  4WWL A;  1T70 A;  2JOG A;  2NXF A;  2BDX A;  3QFK A;  4MOY A;  4TUG A;  4G9J A;  1S3M A;  4V0V A;  4LU9 A;  2HY1 A;  5B8I A;  4KBP A;  4J6O A;  1M63 A;  2IE3 C;  2HYO A;  1S3L A;  4YKE A;  1OID A;  1NNW A;  2HYP A;  3H63 A;  1S8E A;  3IB8 A;  4OR9 A;  2A22 A;  4ZVZ A;  1U32 A;  1JK7 A;  1S95 A;  3EGH A;  4NZV A;  4IL1 A;  4FBK A;  4H2B A;  2USH A;  1TCO A;  4LTY A;  2BQ8 X;  3AUZ A;  2IAE C;  3DSC A;  5IOH A;  4UT3 A;  4FCX A;  5EQV A;  3AV0 A;  1QFC A;  3QFO A;  5J28 A;  2R17 A;  1HPU A;  4H2I A;  1II7 A;  3C9F A;  3QG5 C;  5INB A;  2GJU A;  4UT2 A;  4H2G A;  1XZW A;  3C5W C;  4O4K A;  2NPP C;  1WAR A;  3E7A A;  3DSD A;  3IVD A;  3FGA C;  3CK2 A;  1OI8 A;  2WDD A;  2IE4 C;  4O5G A;  4DSY A;  2NYM C;  2Q8U A;  3H69 A;  3RL3 A;  3EGG A;  2XMO A;  3H67 A;  3PSO A;  4ORB A;  4FBW A;  1V73 A;  3KBP A;  3RL5 A;  2Z72 A;  1HP1 A;  1W24 A;  4UWQ A;  4M0V A;  2O8A A;  1FJM A;  3ICF A;  5C1V A;  3E7B A;  4JA9 A;  3K7V C;  2WDE A;  3IVE A;  1S70 A;  3ZU0 A;  2KKN A;  1AUI A;  2WDF A;  5JJT A;  1MF8 A;  3THN A;  3T1I A;  3GVE A;  1HO5 A;  3TGH A;  5JPE A;  2QFP A;  4H1S A;  4JA7 A;  4DHL A;  1T71 A;  2CV9 A;  2YVT A;  1QHW A;  5GTU A; 
#chains in the Genus database with same CATH topology
 3P71 C;  4I5N C;  2P6B A;  1Z2X A;  3K7W C;  1S3N A;  2ZBM A;  1IT6 A;  2ZO9 B;  4XPN A;  4KKZ A;  4MOV A;  3RL4 A;  4LAC C;  1WAO 1;  3D03 A;  1XM7 A;  4H2F A;  4H1Y P;  4UT3 B;  2NYL C;  2Z1A A;  4IYP C;  3V4Y A;  2Z06 A;  3HVQ A;  4I5L C;  4B2O A;  4DT2 A;  2O8G A;  2BCD A;  4HD0 A;  2ZOA A;  3H66 A;  2WDC A;  1OIE A;  4ZX2 A;  3JYF A;  1Z2W A;  4F0Z A;  1UF3 A;  4ORC A;  5F3W A;  3THO B;  2DXN A;  3QFN A;  4TUI A;  3H64 A;  1SU1 A;  3H60 A;  1UTE A;  4V0W A;  3IB7 A;  4MP0 A;  1USH A;  5JPF A;  1G5B A;  3H68 A;  3N5U A;  4FBQ A;  3PSN A;  5DNY A;  4O24 A;  4O43 A;  3LL8 A;  4V0X A;  3DW8 C;  2QFR A;  4Q7F A;  4ORA A;  3QFM A;  2YEQ A;  3ZTV A;  2QJC A;  3H61 A;  3RQZ A;  2AHD A;  2DFJ A;  5HPE A;  1KBP A;  3H62 B;  4WWL A;  1T70 A;  2JOG A;  2NXF A;  2BDX A;  3QFK A;  4MOY A;  4TUG A;  4G9J A;  1S3M A;  4V0V A;  4LU9 A;  2HY1 A;  5B8I A;  4KBP A;  4J6O A;  1M63 A;  2IE3 C;  2HYO A;  1S3L A;  4YKE A;  1OID A;  1NNW A;  2HYP A;  3H63 A;  1S8E A;  3IB8 A;  4OR9 A;  2A22 A;  4ZVZ A;  1U32 A;  1JK7 A;  1S95 A;  3EGH A;  4NZV A;  4IL1 A;  4FBK A;  4H2B A;  2USH A;  1TCO A;  4LTY A;  2BQ8 X;  3AUZ A;  2IAE C;  3DSC A;  5IOH A;  4UT3 A;  4FCX A;  5EQV A;  3AV0 A;  1QFC A;  3QFO A;  5J28 A;  2R17 A;  1HPU A;  4H2I A;  1II7 A;  3C9F A;  3QG5 C;  5INB A;  2GJU A;  4UT2 A;  4H2G A;  1XZW A;  3C5W C;  4O4K A;  2NPP C;  1WAR A;  3E7A A;  3DSD A;  3IVD A;  3FGA C;  3CK2 A;  1OI8 A;  2WDD A;  2IE4 C;  4O5G A;  4DSY A;  2NYM C;  2Q8U A;  3H69 A;  3RL3 A;  3EGG A;  2XMO A;  3H67 A;  3PSO A;  4ORB A;  4FBW A;  1V73 A;  3KBP A;  3RL5 A;  2Z72 A;  1HP1 A;  1W24 A;  4UWQ A;  4M0V A;  2O8A A;  1FJM A;  3ICF A;  5C1V A;  3E7B A;  4JA9 A;  3K7V C;  2WDE A;  3IVE A;  1S70 A;  2DXL A;  3ZU0 A;  2KKN A;  1AUI A;  2WDF A;  5JJT A;  1MF8 A;  3FLO A;  3THN A;  3T1I A;  3GVE A;  1HO5 A;  3TGH A;  5JPE A;  2QFP A;  4H1S A;  4JA7 A;  4DHL A;  1T71 A;  2CV9 A;  2YVT A;  1QHW A;  5GTU A;  3E0J A; 
#chains in the Genus database with same CATH homology
 3P71 C;  4I5N C;  2P6B A;  1Z2X A;  3K7W C;  1S3N A;  2ZBM A;  1IT6 A;  2ZO9 B;  4XPN A;  4KKZ A;  4MOV A;  3RL4 A;  4LAC C;  1WAO 1;  3D03 A;  1XM7 A;  4H2F A;  4H1Y P;  4UT3 B;  2NYL C;  2Z1A A;  4IYP C;  3V4Y A;  2Z06 A;  3HVQ A;  4I5L C;  4B2O A;  4DT2 A;  2O8G A;  2BCD A;  4HD0 A;  2ZOA A;  3H66 A;  2WDC A;  1OIE A;  4ZX2 A;  3JYF A;  1Z2W A;  4F0Z A;  1UF3 A;  4ORC A;  5F3W A;  3THO B;  2DXN A;  3QFN A;  4TUI A;  3H64 A;  1SU1 A;  3H60 A;  1UTE A;  4V0W A;  3IB7 A;  4MP0 A;  1USH A;  5JPF A;  1G5B A;  3H68 A;  3N5U A;  4FBQ A;  3PSN A;  5DNY A;  4O24 A;  4O43 A;  3LL8 A;  4V0X A;  3DW8 C;  2QFR A;  4Q7F A;  4ORA A;  3QFM A;  2YEQ A;  3ZTV A;  2QJC A;  3H61 A;  3RQZ A;  2AHD A;  2DFJ A;  5HPE A;  1KBP A;  3H62 B;  4WWL A;  1T70 A;  2JOG A;  2NXF A;  2BDX A;  3QFK A;  4MOY A;  4TUG A;  4G9J A;  1S3M A;  4V0V A;  4LU9 A;  2HY1 A;  5B8I A;  4KBP A;  4J6O A;  1M63 A;  2IE3 C;  2HYO A;  1S3L A;  4YKE A;  1OID A;  1NNW A;  2HYP A;  3H63 A;  1S8E A;  3IB8 A;  4OR9 A;  2A22 A;  4ZVZ A;  1U32 A;  1JK7 A;  1S95 A;  3EGH A;  4NZV A;  4IL1 A;  4FBK A;  4H2B A;  2USH A;  1TCO A;  4LTY A;  2BQ8 X;  3AUZ A;  2IAE C;  3DSC A;  5IOH A;  4UT3 A;  4FCX A;  5EQV A;  3AV0 A;  1QFC A;  3QFO A;  5J28 A;  2R17 A;  1HPU A;  4H2I A;  1II7 A;  3C9F A;  3QG5 C;  5INB A;  2GJU A;  4UT2 A;  4H2G A;  1XZW A;  3C5W C;  4O4K A;  2NPP C;  1WAR A;  3E7A A;  3DSD A;  3IVD A;  3FGA C;  3CK2 A;  1OI8 A;  2WDD A;  2IE4 C;  4O5G A;  4DSY A;  2NYM C;  2Q8U A;  3H69 A;  3RL3 A;  3EGG A;  2XMO A;  3H67 A;  3PSO A;  4ORB A;  4FBW A;  1V73 A;  3KBP A;  3RL5 A;  2Z72 A;  1HP1 A;  1W24 A;  4UWQ A;  4M0V A;  2O8A A;  1FJM A;  3ICF A;  5C1V A;  3E7B A;  4JA9 A;  3K7V C;  2WDE A;  3IVE A;  1S70 A;  2DXL A;  3ZU0 A;  2KKN A;  1AUI A;  2WDF A;  5JJT A;  1MF8 A;  3FLO A;  3THN A;  3T1I A;  3GVE A;  1HO5 A;  3TGH A;  5JPE A;  2QFP A;  4H1S A;  4JA7 A;  4DHL A;  1T71 A;  2CV9 A;  2YVT A;  1QHW A;  5GTU A;  3E0J A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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