3RTTA

Human mmp-12 catalytic domain in complex with*(r)-n*-hydroxy-1-(phenethylsulfonyl)pyrrolidine-2-carboxamide
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Contribution of ligand free energy of solvation to design new potent MMPs inhibitors.
rcsb
molecule keywords Macrophage metalloelastase
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 45
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2011-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3rttA00
3RTTA 3G5CA 3KEKA 1MMRA 2MLRA 2O3EA 2MLSA 3DL1A 2OXWA 3L0TA 1SLNA 4XM8A 1Y8JA 4PKWA 1CXVA 1ZVXA 1DMTA 1MNCA 4H1QA 1OM6A 1CGFA 1GO7P 3O64A 4H82A 3EDHA 1BIWA 1GE6A 1KUFA 1SU3A 4L6TA 4IN9A 3GBOA 2OXUA 3OHLA 1CGLA 2EROA 5L7FA 1A85A 1ND1A 1FM1A 3DNGA 4XM6A 3LJTA 1BKCA 3I7GA 4EFSA 1CGEA 1IACA 2OW9A 5CXAA 2N8RA 1G05A 3OHOA 1EUBA 4J4MA 1A86A 1ZTQA 1L6JA 3KWVC 2Z2DA 4ILWD 4H3XA 4AXQA 1QJJA 4FXYP 3LJGA 4XM7A 966CA 1D5JA 2X3CA 2D1OA 3P24A 4AYKA 1ASTA 1OMJA 1PWVA 4I03A 2YB9A 1KUGA 1UMSA 2JIHA 2K9CA 5L79A 3LE9A 2WOAA 3ZVSA 1QJIA 4PKQA 3LIKA 3V96B 1GXDA 3VTGA 4HMAA 1O0QA 2J83A 4H2EA 1HFCA 1XURA 4DPEA 3DPFA 1YOUA 1ATLA 2OXZA 1DTHA 1JK3A 1ROSA 4JA1A 2JT6A 1Z3JA 4CTHA 2TCLA 1IAGA 1BQOA 3USNA 3HYGA 2X3AA 4PKTA 2E3XA 1BQQM 4PKRA 1GKCA 1GO8P 3HDAP 3HB2P 2OW1A 1JH1A 2RJQA 2KRJA 5I43A 4G0DA 3F18A 1C8TA 1IAAA 2V4BA 3I7IA 5JMYA 1I73A 5D1UA 1KUKA 1ZXCA 1CK7A 2ERPA 3K7LA 3AYUA 3EDGA 5D1SA 2W12A 2ERQA 4HX3A 2OZRA 1GKDA 1K7QA 4WKIA 4XCTA 3TS4A 1XFUA 2DW2A 3LUNA 4L63A 3E8RA 3Q2GA 3WV3A 1R55A 3DPEA 1IABA 3F19A 3DSLA 2Y6CA 4PKSA 1HTDA 1QUAA 3KMEA 3UVCA 3KRYA 4GR8A 4H49A 2X7MA 2K2GA 1AYKA 1G49A 1XFZA 1JANA 3AIGA 5H8XA 2E2DA 3B92A 2MZHA 1HV5A 2OVXA 2O36A 4DV8A 1D8FA 1SMPA 1K7GA 1RMZA 4WZVA 3LKAA 2DW1A 3F15A 3AYKA 1BM6A 2W0DA 3RTSA 3Q2HA 3NX7A 1PWPA 4GR0A 456CA 1ZXVA 1EAKA 2W15A 2L0RA 3TT4A 1CQRA 4QKZA 1PWQA 1YCMA 2DDYA 1OS9A 3F17A 1D8MA 4DD8A 1G12A 1OS2A 1PWWA 3SHIA 4IUWA 2QPJA 3TSKA 4GWNA 4IJOA 3ZXHA 5I0LA 1JAPA 3LIRA 4GR3A 3KECA 2AIGP 2SRTA 2DW0A 4ON1A 3U1RA 1WNIA 1HFSA 3EWJA 3LUMA 3KMCA 1BSWA 1I1IP 1G9KA 1XFVA 4PKUA 3HBVP 3KHIA 4WF6A 1H71P 1GE7A 1MMQA 2WO9A 3HY9A 4JPAA 1BUVM 1YP1A 1J7NA 2D1NA 3EDZA 3K7NA 3LGPA 3DWBA 1O0TA 3LJZA 1C3IA 1B8YA 3B8ZA 2PJTA 1BZSA 1EB6A 1JIWP 4XBHA 5B5OA 1AKLA 1R1JA 3EDIA 2FV5A 1UTZA 5BOYA 2YIGA 1OO9A 3HBUP 4PKVA 3N2VA 1GE5A 4Q1LA 2WO8A 1Q3AA 3N2UA 3EHXA 2DDFA 2I47A 1SLMA 3WV2A 3LQBA 1XFWA 1C7KA 1FLSA 3L0VA 1QIBA 4H30A 1MMPA 1XUCA 1Y0VA 5D3CA 3BA0A 1Y93A 2OW2A 2JNPA 1RM8A 4GWMA 4R3VA 1USNA 4JQGA 3LMCA 5I4OA 1YQYA 1BKCE 3WV1A 3F16A 1IAEA 1CAQA 830CA 2HU6A 4H84A 2OY4A 2OVZA 5I3MA 4G9LA 3CKIA 2OW0A 1XUDA 5BOTA 1KAPP 1XFYA 1BKCI 1R1IA 4A7BA 1I76A 2JT5A 1BUDA 2OY2A 2MZIA 1OM8A 2J0TA 3HY7A 5CZMA 1AF0A 1K7IA 2RJPA 5LABA 4WK7A 3B2ZA 2USNA 1S4BP 4ZR5A 1MMBA 5D2BA 1ZP5A 1JKYA 1QIAA 1KUIA 3HDBA 1G4KA 1JAOA 1B3DA 1UTTA 2W14A 1UEAA 1KBCA 1JJ9A 1ZS0A 1XFXA 1CIZA 1KUHA 1UMTA 1R1HA 2CKIA 1D7XA 2AYKA 3MA2A 3KEJA 2POJA 1R54A 5I12A 1IADA 1OM7A 3ZUKA 1HOVA 2MZEA 4FXQA 3G42A 3LK8A 4FVLA 4JP4A 4I35A 2JSDA 5CUHA 4H76A 1QICA 2XS3A 4AIGA 3P1VA 4WKEA 5D1TA 1PWUA 2OI0A 1JAQA 4GQLA 1SATA 2CLTA 4L19A 2FV9A 4GUYA 3ELMA 5B5PA 3LILA 3O2XA 4FU4A 2A8HA 3EHYA 5BPAA 4JIJA 1SRPA 5D7WA 4DF9A 2Y6DA 1HY7A 2W13A 3LEAA 3LQ0A 4A3WA 4AUOA 2X3BA 2XS4A 4GF1A 3TVCA 1JIZA 3VI1A 3F1AA 5I2ZA 1FBLA
chains in the Genus database with same CATH superfamily
3RTTA 3G5CA 3KEKA 1MMRA 2MLRA 2O3EA 2MLSA 3DL1A 2OXWA 3L0TA 1SLNA 4XM8A 1Y8JA 4PKWA 1CXVA 1ZVXA 1DMTA 1MNCA 4H1QA 1OM6A 1CGFA 1GO7P 3O64A 4H82A 3EDHA 1BIWA 1GE6A 1KUFA 1SU3A 4L6TA 4IN9A 3GBOA 2OXUA 3OHLA 1CGLA 2EROA 5L7FA 1A85A 1ND1A 1FM1A 3DNGA 4XM6A 3LJTA 1BKCA 3I7GA 4EFSA 1CGEA 1IACA 2OW9A 5CXAA 2N8RA 1G05A 3OHOA 1EUBA 4J4MA 1A86A 1ZTQA 1L6JA 3KWVC 2Z2DA 4ILWD 4H3XA 4AXQA 1QJJA 4FXYP 3LJGA 4XM7A 966CA 1D5JA 2X3CA 2D1OA 3P24A 4AYKA 1ASTA 1OMJA 1PWVA 4I03A 2YB9A 1KUGA 1UMSA 2JIHA 2K9CA 5L79A 3LE9A 2WOAA 3ZVSA 1QJIA 4PKQA 3LIKA 3V96B 1GXDA 3VTGA 4HMAA 1O0QA 2J83A 4H2EA 1HFCA 1XURA 4DPEA 3DPFA 1YOUA 1ATLA 2OXZA 1DTHA 1JK3A 1ROSA 4JA1A 2JT6A 1Z3JA 4CTHA 2TCLA 3DTKA 1IAGA 1BQOA 3USNA 3HYGA 2X3AA 4PKTA 2E3XA 1BQQM 4PKRA 1GKCA 1GO8P 3HDAP 3HB2P 2OW1A 1JH1A 2RJQA 2KRJA 5I43A 4G0DA 3F18A 1C8TA 1IAAA 1OZ9A 2V4BA 3I7IA 5JMYA 1I73A 5D1UA 1KUKA 1ZXCA 1CK7A 2ERPA 3K7LA 3AYUA 3EDGA 5D1SA 2W12A 2ERQA 4HX3A 2OZRA 1GKDA 1K7QA 4WKIA 4XCTA 3TS4A 1XFUA 2DW2A 3LUNA 4L63A 3E8RA 3Q2GA 3WV3A 1R55A 3DPEA 1IABA 3F19A 3DTIA 3DSLA 2Y6CA 4PKSA 1HTDA 1QUAA 3KMEA 3UVCA 3KRYA 4GR8A 4H49A 2X7MA 2K2GA 1AYKA 1G49A 1XFZA 1JANA 3AIGA 5H8XA 2E2DA 3B92A 2MZHA 1HV5A 2OVXA 2O36A 4DV8A 1D8FA 1SMPA 1K7GA 1RMZA 4WZVA 3LKAA 2DW1A 3F15A 3AYKA 1BM6A 2W0DA 3RTSA 3Q2HA 3NX7A 1PWPA 4GR0A 456CA 1ZXVA 1EAKA 2W15A 2L0RA 3TT4A 1CQRA 4QKZA 1PWQA 1YCMA 2DDYA 1OS9A 3F17A 1D8MA 4DD8A 1G12A 1OS2A 4L7AA 1PWWA 3SHIA 4IUWA 2QPJA 3TSKA 4GWNA 4IJOA 3ZXHA 5I0LA 1JAPA 3LIRA 4GR3A 3KECA 2AIGP 2SRTA 2DW0A 4ON1A 3U1RA 1WNIA 1HFSA 3EWJA 3LUMA 3KMCA 1BSWA 1I1IP 1G9KA 1XFVA 4PKUA 3HBVP 3KHIA 4WF6A 1H71P 1GE7A 1MMQA 2WO9A 3HY9A 1XM5A 4JPAA 1BUVM 1YP1A 1J7NA 2D1NA 3EDZA 3K7NA 3LGPA 3DWBA 1O0TA 3LJZA 1C3IA 1B8YA 3B8ZA 2PJTA 1BZSA 1EB6A 1JIWP 4XBHA 5B5OA 1AKLA 1R1JA 3EDIA 2FV5A 1UTZA 5BOYA 2YIGA 1OO9A 3HBUP 4PKVA 3N2VA 1GE5A 4Q1LA 2WO8A 1Q3AA 3N2UA 3EHXA 2DDFA 2I47A 1SLMA 3WV2A 3LQBA 1XFWA 2YUFA 1C7KA 1FLSA 3L0VA 1QIBA 4H30A 1MMPA 1XUCA 1Y0VA 5D3CA 3BA0A 3DTEA 1Y93A 2OW2A 2JNPA 1RM8A 4GWMA 4R3VA 1USNA 4JQGA 3LMCA 5I4OA 1YQYA 1BKCE 3WV1A 3F16A 1IAEA 1CAQA 830CA 2HU6A 4H84A 2OY4A 2OVZA 5I3MA 4G9LA 3CKIA 2OW0A 1XUDA 5BOTA 1KAPP 1XFYA 1BKCI 1R1IA 4A7BA 1I76A 2JT5A 1BUDA 2OY2A 2MZIA 1OM8A 2J0TA 3HY7A 5CZMA 1AF0A 1K7IA 2RJPA 5LABA 4WK7A 3B2ZA 2USNA 1S4BP 4ZR5A 1MMBA 5D2BA 1ZP5A 1JKYA 1QIAA 1KUIA 3HDBA 1G4KA 1JAOA 1B3DA 1UTTA 2W14A 1UEAA 1KBCA 1JJ9A 1ZS0A 1XFXA 1CIZA 1KUHA 1UMTA 1R1HA 2CKIA 1D7XA 2AYKA 3MA2A 3KEJA 2POJA 1R54A 5I12A 1IADA 1OM7A 3ZUKA 1HOVA 2MZEA 4FXQA 3G42A 3LK8A 4FVLA 4JP4A 4I35A 2JSDA 5CUHA 1XAXA 4H76A 1QICA 2XS3A 4AIGA 3P1VA 4WKEA 5D1TA 1PWUA 2OI0A 1JAQA 4GQLA 1SATA 2CLTA 4L19A 2FV9A 4GUYA 3ELMA 5B5PA 3LILA 3O2XA 1TVIA 4FU4A 2A8HA 3EHYA 5BPAA 4JIJA 1SRPA 5D7WA 4DF9A 2Y6DA 1HY7A 2W13A 3LEAA 3LQ0A 4A3WA 4AUOA 2X3BA 2XS4A 4GF1A 3TVCA 1JIZA 3VI1A 3F1AA 5I2ZA 1FBLA
chains in the Genus database with same CATH topology
3RTTA 3G5CA 3KEKA 1MMRA 2MLRA 2O3EA 2MLSA 3DL1A 2OXWA 3L0TA 1SLNA 4XM8A 1Y8JA 4PKWA 1CXVA 1ZVXA 1DMTA 1MNCA 4H1QA 1OM6A 1CGFA 1GO7P 3O64A 4H82A 3EDHA 1BIWA 1GE6A 1KUFA 1SU3A 4L6TA 4IN9A 3GBOA 2OXUA 3OHLA 1CGLA 2EROA 5L7FA 1A85A 1ND1A 1FM1A 3DNGA 4XM6A 3LJTA 1BKCA 3I7GA 4EFSA 1CGEA 1IACA 2OW9A 5CXAA 2N8RA 1G05A 3OHOA 1EUBA 4J4MA 1A86A 1ZTQA 1L6JA 3KWVC 2Z2DA 4ILWD 4H3XA 4AXQA 1QJJA 4FXYP 3LJGA 4XM7A 966CA 1D5JA 2X3CA 2D1OA 3P24A 4AYKA 1ASTA 1OMJA 1PWVA 4I03A 2YB9A 1KUGA 1UMSA 2JIHA 2K9CA 5L79A 3LE9A 2WOAA 3ZVSA 1QJIA 4PKQA 3LIKA 3V96B 1GXDA 3VTGA 4HMAA 1O0QA 2J83A 4H2EA 1HFCA 1XURA 4DPEA 3DPFA 1YOUA 1ATLA 2OXZA 1DTHA 1JK3A 1ROSA 4JA1A 2JT6A 1Z3JA 4CTHA 2TCLA 3DTKA 1IAGA 1BQOA 3USNA 3HYGA 2X3AA 4PKTA 2E3XA 1BQQM 4PKRA 1GKCA 1GO8P 3HDAP 3HB2P 2OW1A 1JH1A 2RJQA 2KRJA 5I43A 4G0DA 3F18A 1C8TA 1IAAA 2V4BA 3I7IA 5JMYA 1I73A 5D1UA 1KUKA 1ZXCA 1CK7A 2ERPA 3K7LA 3AYUA 3EDGA 5D1SA 2W12A 2ERQA 4HX3A 2OZRA 1GKDA 1K7QA 4WKIA 4XCTA 3TS4A 1XFUA 2DW2A 3LUNA 4L63A 3E8RA 3Q2GA 3WV3A 1R55A 3DPEA 1IABA 3F19A 3DTIA 3DSLA 2Y6CA 4PKSA 1HTDA 1QUAA 3KMEA 3UVCA 3KRYA 4GR8A 4H49A 2X7MA 2K2GA 1AYKA 1G49A 1XFZA 1JANA 3AIGA 5H8XA 2E2DA 3B92A 2MZHA 1HV5A 2OVXA 2O36A 4DV8A 1D8FA 1SMPA 1K7GA 1RMZA 4WZVA 3LKAA 2DW1A 3F15A 3AYKA 1BM6A 2W0DA 3RTSA 3Q2HA 3NX7A 1PWPA 4GR0A 456CA 1ZXVA 1EAKA 2W15A 2L0RA 3TT4A 1CQRA 4QKZA 1PWQA 1YCMA 2DDYA 1OS9A 3F17A 1D8MA 4DD8A 1G12A 1OS2A 4L7AA 1PWWA 3SHIA 4IUWA 2QPJA 3TSKA 4GWNA 4IJOA 3ZXHA 5I0LA 1JAPA 3LIRA 4GR3A 3KECA 2AIGP 2SRTA 2DW0A 4ON1A 3U1RA 1WNIA 1HFSA 3EWJA 3LUMA 3KMCA 1BSWA 1I1IP 1G9KA 1XFVA 4PKUA 3HBVP 3KHIA 4WF6A 1H71P 1GE7A 1MMQA 2WO9A 3HY9A 4JPAA 1BUVM 1YP1A 1J7NA 2D1NA 3EDZA 3K7NA 3LGPA 3DWBA 1O0TA 3LJZA 1C3IA 1B8YA 3B8ZA 2PJTA 1BZSA 1EB6A 1JIWP 4XBHA 5B5OA 1AKLA 1R1JA 3EDIA 2FV5A 1UTZA 5BOYA 2YIGA 1OO9A 3HBUP 4PKVA 3N2VA 1GE5A 4Q1LA 2WO8A 1Q3AA 3N2UA 3EHXA 2DDFA 2I47A 1SLMA 3WV2A 3LQBA 1XFWA 2YUFA 1C7KA 1FLSA 3L0VA 1QIBA 4H30A 1MMPA 1XUCA 1Y0VA 5D3CA 3BA0A 3DTEA 1Y93A 2OW2A 2JNPA 1RM8A 4GWMA 4R3VA 1USNA 4JQGA 3LMCA 5I4OA 1YQYA 1BKCE 3WV1A 3F16A 1IAEA 1CAQA 830CA 2HU6A 4H84A 2OY4A 2OVZA 5I3MA 4G9LA 3CKIA 2OW0A 1XUDA 5BOTA 1KAPP 1XFYA 1BKCI 1R1IA 4A7BA 1I76A 2JT5A 1BUDA 2OY2A 2MZIA 1OM8A 2J0TA 3HY7A 5CZMA 1AF0A 1K7IA 2RJPA 5LABA 4WK7A 3B2ZA 2USNA 1S4BP 4ZR5A 1MMBA 5D2BA 1ZP5A 1JKYA 1QIAA 1KUIA 3HDBA 1G4KA 1JAOA 1B3DA 1UTTA 2W14A 1UEAA 1KBCA 1JJ9A 1ZS0A 1XFXA 1CIZA 1KUHA 1UMTA 1R1HA 2CKIA 1D7XA 2AYKA 3MA2A 3KEJA 2POJA 1R54A 5I12A 1IADA 1OM7A 3ZUKA 1HOVA 2MZEA 4FXQA 3G42A 3LK8A 4FVLA 4JP4A 4I35A 2JSDA 5CUHA 4H76A 1QICA 2XS3A 4AIGA 3P1VA 4WKEA 5D1TA 1PWUA 2OI0A 1JAQA 4GQLA 1SATA 2CLTA 4L19A 2FV9A 4GUYA 3ELMA 5B5PA 3LILA 3O2XA 4FU4A 2A8HA 3EHYA 5BPAA 4JIJA 1SRPA 5D7WA 4DF9A 2Y6DA 1HY7A 2W13A 3LEAA 3LQ0A 4A3WA 4AUOA 2X3BA 2XS4A 4GF1A 3TVCA 1JIZA 3VI1A 3F1AA 5I2ZA 1FBLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RTT A;  3G5C A;  3KEK A;  1MMR A;  2MLR A;  2O3E A;  2MLS A;  3DL1 A;  2OXW A;  3L0T A;  1SLN A;  4XM8 A;  1Y8J A;  4PKW A;  1CXV A;  1ZVX A;  1DMT A;  1MNC A;  4H1Q A;  1OM6 A;  1CGF A;  1GO7 P;  3O64 A;  4H82 A;  3EDH A;  1BIW A;  1GE6 A;  1KUF A;  1SU3 A;  4L6T A;  4IN9 A;  3GBO A;  2OXU A;  3OHL A;  1CGL A;  2ERO A;  5L7F A;  1A85 A;  1ND1 A;  1FM1 A;  3DNG A;  4XM6 A;  3LJT A;  1BKC A;  3I7G A;  4EFS A;  1CGE A;  1IAC A;  2OW9 A;  5CXA A;  2N8R A;  1G05 A;  3OHO A;  1EUB A;  4J4M A;  1A86 A;  1ZTQ A;  1L6J A;  3KWV C;  2Z2D A;  4ILW D;  4H3X A;  4AXQ A;  1QJJ A;  4FXY P;  3LJG A;  4XM7 A;  966C A;  1D5J A;  2X3C A;  2D1O A;  3P24 A;  4AYK A;  1AST A;  1OMJ A;  1PWV A;  4I03 A;  2YB9 A;  1KUG A;  1UMS A;  2JIH A;  2K9C A;  5L79 A;  3LE9 A;  2WOA A;  3ZVS A;  1QJI A;  4PKQ A;  3LIK A;  3V96 B;  1GXD A;  3VTG A;  4HMA A;  1O0Q A;  2J83 A;  4H2E A;  1HFC A;  1XUR A;  4DPE A;  3DPF A;  1YOU A;  1ATL A;  2OXZ A;  1DTH A;  1JK3 A;  1ROS A;  4JA1 A;  2JT6 A;  1Z3J A;  4CTH A;  2TCL A;  1IAG A;  1BQO A;  3USN A;  3HYG A;  2X3A A;  4PKT A;  2E3X A;  1BQQ M;  4PKR A;  1GKC A;  1GO8 P;  3HDA P;  3HB2 P;  2OW1 A;  1JH1 A;  2RJQ A;  2KRJ A;  5I43 A;  4G0D A;  3F18 A;  1C8T A;  1IAA A;  2V4B A;  3I7I A;  5JMY A;  1I73 A;  5D1U A;  1KUK A;  1ZXC A;  1CK7 A;  2ERP A;  3K7L A;  3AYU A;  3EDG A;  5D1S A;  2W12 A;  2ERQ A;  4HX3 A;  2OZR A;  1GKD A;  1K7Q A;  4WKI A;  4XCT A;  3TS4 A;  1XFU A;  2DW2 A;  3LUN A;  4L63 A;  3E8R A;  3Q2G A;  3WV3 A;  1R55 A;  3DPE A;  1IAB A;  3F19 A;  3DSL A;  2Y6C A;  4PKS A;  1HTD A;  1QUA A;  3KME A;  3UVC A;  3KRY A;  4GR8 A;  4H49 A;  2X7M A;  2K2G A;  1AYK A;  1G49 A;  1XFZ A;  1JAN A;  3AIG A;  5H8X A;  2E2D A;  3B92 A;  2MZH A;  1HV5 A;  2OVX A;  2O36 A;  4DV8 A;  1D8F A;  1SMP A;  1K7G A;  1RMZ A;  4WZV A;  3LKA A;  2DW1 A;  3F15 A;  3AYK A;  1BM6 A;  2W0D A;  3RTS A;  3Q2H A;  3NX7 A;  1PWP A;  4GR0 A;  456C A;  1ZXV A;  1EAK A;  2W15 A;  2L0R A;  3TT4 A;  1CQR A;  4QKZ A;  1PWQ A;  1YCM A;  2DDY A;  1OS9 A;  3F17 A;  1D8M A;  4DD8 A;  1G12 A;  1OS2 A;  1PWW A;  3SHI A;  4IUW A;  2QPJ A;  3TSK A;  4GWN A;  4IJO A;  3ZXH A;  5I0L A;  1JAP A;  3LIR A;  4GR3 A;  3KEC A;  2AIG P;  2SRT A;  2DW0 A;  4ON1 A;  3U1R A;  1WNI A;  1HFS A;  3EWJ A;  3LUM A;  3KMC A;  1BSW A;  1I1I P;  1G9K A;  1XFV A;  4PKU A;  3HBV P;  3KHI A;  4WF6 A;  1H71 P;  1GE7 A;  1MMQ A;  2WO9 A;  3HY9 A;  4JPA A;  1BUV M;  1YP1 A;  1J7N A;  2D1N A;  3EDZ A;  3K7N A;  3LGP A;  3DWB A;  1O0T A;  3LJZ A;  1C3I A;  1B8Y A;  3B8Z A;  2PJT A;  1BZS A;  1EB6 A;  1JIW P;  4XBH A;  5B5O A;  1AKL A;  1R1J A;  3EDI A;  2FV5 A;  1UTZ A;  5BOY A;  2YIG A;  1OO9 A;  3HBU P;  4PKV A;  3N2V A;  1GE5 A;  4Q1L A;  2WO8 A;  1Q3A A;  3N2U A;  3EHX A;  2DDF A;  2I47 A;  1SLM A;  3WV2 A;  3LQB A;  1XFW A;  1C7K A;  1FLS A;  3L0V A;  1QIB A;  4H30 A;  1MMP A;  1XUC A;  1Y0V A;  5D3C A;  3BA0 A;  1Y93 A;  2OW2 A;  2JNP A;  1RM8 A;  4GWM A;  4R3V A;  1USN A;  4JQG A;  3LMC A;  5I4O A;  1YQY A;  1BKC E;  3WV1 A;  3F16 A;  1IAE A;  1CAQ A;  830C A;  2HU6 A;  4H84 A;  2OY4 A;  2OVZ A;  5I3M A;  4G9L A;  3CKI A;  2OW0 A;  1XUD A;  5BOT A;  1KAP P;  1XFY A;  1BKC I;  1R1I A;  4A7B A;  1I76 A;  2JT5 A;  1BUD A;  2OY2 A;  2MZI A;  1OM8 A;  2J0T A;  3HY7 A;  5CZM A;  1AF0 A;  1K7I A;  2RJP A;  5LAB A;  4WK7 A;  3B2Z A;  2USN A;  1S4B P;  4ZR5 A;  1MMB A;  5D2B A;  1ZP5 A;  1JKY A;  1QIA A;  1KUI A;  3HDB A;  1G4K A;  1JAO A;  1B3D A;  1UTT A;  2W14 A;  1UEA A;  1KBC A;  1JJ9 A;  1ZS0 A;  1XFX A;  1CIZ A;  1KUH A;  1UMT A;  1R1H A;  2CKI A;  1D7X A;  2AYK A;  3MA2 A;  3KEJ A;  2POJ A;  1R54 A;  5I12 A;  1IAD A;  1OM7 A;  3ZUK A;  1HOV A;  2MZE A;  4FXQ A;  3G42 A;  3LK8 A;  4FVL A;  4JP4 A;  4I35 A;  2JSD A;  5CUH A;  4H76 A;  1QIC A;  2XS3 A;  4AIG A;  3P1V A;  4WKE A;  5D1T A;  1PWU A;  2OI0 A;  1JAQ A;  4GQL A;  1SAT A;  2CLT A;  4L19 A;  2FV9 A;  4GUY A;  3ELM A;  5B5P A;  3LIL A;  3O2X A;  4FU4 A;  2A8H A;  3EHY A;  5BPA A;  4JIJ A;  1SRP A;  5D7W A;  4DF9 A;  2Y6D A;  1HY7 A;  2W13 A;  3LEA A;  3LQ0 A;  4A3W A;  4AUO A;  2X3B A;  2XS4 A;  4GF1 A;  3TVC A;  1JIZ A;  3VI1 A;  3F1A A;  5I2Z A;  1FBL A; 
#chains in the Genus database with same CATH topology
 3RTT A;  3G5C A;  3KEK A;  1MMR A;  2MLR A;  2O3E A;  2MLS A;  3DL1 A;  2OXW A;  3L0T A;  1SLN A;  4XM8 A;  1Y8J A;  4PKW A;  1CXV A;  1ZVX A;  1DMT A;  1MNC A;  4H1Q A;  1OM6 A;  1CGF A;  1GO7 P;  3O64 A;  4H82 A;  3EDH A;  1BIW A;  1GE6 A;  1KUF A;  1SU3 A;  4L6T A;  4IN9 A;  3GBO A;  2OXU A;  3OHL A;  1CGL A;  2ERO A;  5L7F A;  1A85 A;  1ND1 A;  1FM1 A;  3DNG A;  4XM6 A;  3LJT A;  1BKC A;  3I7G A;  4EFS A;  1CGE A;  1IAC A;  2OW9 A;  5CXA A;  2N8R A;  1G05 A;  3OHO A;  1EUB A;  4J4M A;  1A86 A;  1ZTQ A;  1L6J A;  3KWV C;  2Z2D A;  4ILW D;  4H3X A;  4AXQ A;  1QJJ A;  4FXY P;  3LJG A;  4XM7 A;  966C A;  1D5J A;  2X3C A;  2D1O A;  3P24 A;  4AYK A;  1AST A;  1OMJ A;  1PWV A;  4I03 A;  2YB9 A;  1KUG A;  1UMS A;  2JIH A;  2K9C A;  5L79 A;  3LE9 A;  2WOA A;  3ZVS A;  1QJI A;  4PKQ A;  3LIK A;  3V96 B;  1GXD A;  3VTG A;  4HMA A;  1O0Q A;  2J83 A;  4H2E A;  1HFC A;  1XUR A;  4DPE A;  3DPF A;  1YOU A;  1ATL A;  2OXZ A;  1DTH A;  1JK3 A;  1ROS A;  4JA1 A;  2JT6 A;  1Z3J A;  4CTH A;  2TCL A;  3DTK A;  1IAG A;  1BQO A;  3USN A;  3HYG A;  2X3A A;  4PKT A;  2E3X A;  1BQQ M;  4PKR A;  1GKC A;  1GO8 P;  3HDA P;  3HB2 P;  2OW1 A;  1JH1 A;  2RJQ A;  2KRJ A;  5I43 A;  4G0D A;  3F18 A;  1C8T A;  1IAA A;  1OZ9 A;  2V4B A;  3I7I A;  5JMY A;  1I73 A;  5D1U A;  1KUK A;  1ZXC A;  1CK7 A;  2ERP A;  3K7L A;  3AYU A;  3EDG A;  5D1S A;  2W12 A;  2ERQ A;  4HX3 A;  2OZR A;  1GKD A;  1K7Q A;  4WKI A;  4XCT A;  3TS4 A;  1XFU A;  2DW2 A;  3LUN A;  4L63 A;  3E8R A;  3Q2G A;  3WV3 A;  1R55 A;  3DPE A;  1IAB A;  3F19 A;  3DTI A;  3DSL A;  2Y6C A;  4PKS A;  1HTD A;  1QUA A;  3KME A;  3UVC A;  3KRY A;  4GR8 A;  4H49 A;  2X7M A;  2K2G A;  1AYK A;  1G49 A;  1XFZ A;  1JAN A;  3AIG A;  5H8X A;  2E2D A;  3B92 A;  2MZH A;  1HV5 A;  2OVX A;  2O36 A;  4DV8 A;  1D8F A;  1SMP A;  1K7G A;  1RMZ A;  4WZV A;  3LKA A;  2DW1 A;  3F15 A;  3AYK A;  1BM6 A;  2W0D A;  3RTS A;  3Q2H A;  3NX7 A;  1PWP A;  4GR0 A;  456C A;  1ZXV A;  1EAK A;  2W15 A;  2L0R A;  3TT4 A;  1CQR A;  4QKZ A;  1PWQ A;  1YCM A;  2DDY A;  1OS9 A;  3F17 A;  1D8M A;  4DD8 A;  1G12 A;  1OS2 A;  4L7A A;  1PWW A;  3SHI A;  4IUW A;  2QPJ A;  3TSK A;  4GWN A;  4IJO A;  3ZXH A;  5I0L A;  1JAP A;  3LIR A;  4GR3 A;  3KEC A;  2AIG P;  2SRT A;  2DW0 A;  4ON1 A;  3U1R A;  1WNI A;  1HFS A;  3EWJ A;  3LUM A;  3KMC A;  1BSW A;  1I1I P;  1G9K A;  1XFV A;  4PKU A;  3HBV P;  3KHI A;  4WF6 A;  1H71 P;  1GE7 A;  1MMQ A;  2WO9 A;  3HY9 A;  1XM5 A;  4JPA A;  1BUV M;  1YP1 A;  1J7N A;  2D1N A;  3EDZ A;  3K7N A;  3LGP A;  3DWB A;  1O0T A;  3LJZ A;  1C3I A;  1B8Y A;  3B8Z A;  2PJT A;  1BZS A;  1EB6 A;  1JIW P;  4XBH A;  5B5O A;  1AKL A;  1R1J A;  3EDI A;  2FV5 A;  1UTZ A;  5BOY A;  2YIG A;  1OO9 A;  3HBU P;  4PKV A;  3N2V A;  1GE5 A;  4Q1L A;  2WO8 A;  1Q3A A;  3N2U A;  3EHX A;  2DDF A;  2I47 A;  1SLM A;  3WV2 A;  3LQB A;  1XFW A;  2YUF A;  1C7K A;  1FLS A;  3L0V A;  1QIB A;  4H30 A;  1MMP A;  1XUC A;  1Y0V A;  5D3C A;  3BA0 A;  3DTE A;  1Y93 A;  2OW2 A;  2JNP A;  1RM8 A;  4GWM A;  4R3V A;  1USN A;  4JQG A;  3LMC A;  5I4O A;  1YQY A;  1BKC E;  3WV1 A;  3F16 A;  1IAE A;  1CAQ A;  830C A;  2HU6 A;  4H84 A;  2OY4 A;  2OVZ A;  5I3M A;  4G9L A;  3CKI A;  2OW0 A;  1XUD A;  5BOT A;  1KAP P;  1XFY A;  1BKC I;  1R1I A;  4A7B A;  1I76 A;  2JT5 A;  1BUD A;  2OY2 A;  2MZI A;  1OM8 A;  2J0T A;  3HY7 A;  5CZM A;  1AF0 A;  1K7I A;  2RJP A;  5LAB A;  4WK7 A;  3B2Z A;  2USN A;  1S4B P;  4ZR5 A;  1MMB A;  5D2B A;  1ZP5 A;  1JKY A;  1QIA A;  1KUI A;  3HDB A;  1G4K A;  1JAO A;  1B3D A;  1UTT A;  2W14 A;  1UEA A;  1KBC A;  1JJ9 A;  1ZS0 A;  1XFX A;  1CIZ A;  1KUH A;  1UMT A;  1R1H A;  2CKI A;  1D7X A;  2AYK A;  3MA2 A;  3KEJ A;  2POJ A;  1R54 A;  5I12 A;  1IAD A;  1OM7 A;  3ZUK A;  1HOV A;  2MZE A;  4FXQ A;  3G42 A;  3LK8 A;  4FVL A;  4JP4 A;  4I35 A;  2JSD A;  5CUH A;  1XAX A;  4H76 A;  1QIC A;  2XS3 A;  4AIG A;  3P1V A;  4WKE A;  5D1T A;  1PWU A;  2OI0 A;  1JAQ A;  4GQL A;  1SAT A;  2CLT A;  4L19 A;  2FV9 A;  4GUY A;  3ELM A;  5B5P A;  3LIL A;  3O2X A;  1TVI A;  4FU4 A;  2A8H A;  3EHY A;  5BPA A;  4JIJ A;  1SRP A;  5D7W A;  4DF9 A;  2Y6D A;  1HY7 A;  2W13 A;  3LEA A;  3LQ0 A;  4A3W A;  4AUO A;  2X3B A;  2XS4 A;  4GF1 A;  3TVC A;  1JIZ A;  3VI1 A;  3F1A A;  5I2Z A;  1FBL A; 
#chains in the Genus database with same CATH homology
 3RTT A;  3G5C A;  3KEK A;  1MMR A;  2MLR A;  2O3E A;  2MLS A;  3DL1 A;  2OXW A;  3L0T A;  1SLN A;  4XM8 A;  1Y8J A;  4PKW A;  1CXV A;  1ZVX A;  1DMT A;  1MNC A;  4H1Q A;  1OM6 A;  1CGF A;  1GO7 P;  3O64 A;  4H82 A;  3EDH A;  1BIW A;  1GE6 A;  1KUF A;  1SU3 A;  4L6T A;  4IN9 A;  3GBO A;  2OXU A;  3OHL A;  1CGL A;  2ERO A;  5L7F A;  1A85 A;  1ND1 A;  1FM1 A;  3DNG A;  4XM6 A;  3LJT A;  1BKC A;  3I7G A;  4EFS A;  1CGE A;  1IAC A;  2OW9 A;  5CXA A;  2N8R A;  1G05 A;  3OHO A;  1EUB A;  4J4M A;  1A86 A;  1ZTQ A;  1L6J A;  3KWV C;  2Z2D A;  4ILW D;  4H3X A;  4AXQ A;  1QJJ A;  4FXY P;  3LJG A;  4XM7 A;  966C A;  1D5J A;  2X3C A;  2D1O A;  3P24 A;  4AYK A;  1AST A;  1OMJ A;  1PWV A;  4I03 A;  2YB9 A;  1KUG A;  1UMS A;  2JIH A;  2K9C A;  5L79 A;  3LE9 A;  2WOA A;  3ZVS A;  1QJI A;  4PKQ A;  3LIK A;  3V96 B;  1GXD A;  3VTG A;  4HMA A;  1O0Q A;  2J83 A;  4H2E A;  1HFC A;  1XUR A;  4DPE A;  3DPF A;  1YOU A;  1ATL A;  2OXZ A;  1DTH A;  1JK3 A;  1ROS A;  4JA1 A;  2JT6 A;  1Z3J A;  4CTH A;  2TCL A;  3DTK A;  1IAG A;  1BQO A;  3USN A;  3HYG A;  2X3A A;  4PKT A;  2E3X A;  1BQQ M;  4PKR A;  1GKC A;  1GO8 P;  3HDA P;  3HB2 P;  2OW1 A;  1JH1 A;  2RJQ A;  2KRJ A;  5I43 A;  4G0D A;  3F18 A;  1C8T A;  1IAA A;  2V4B A;  3I7I A;  5JMY A;  1I73 A;  5D1U A;  1KUK A;  1ZXC A;  1CK7 A;  2ERP A;  3K7L A;  3AYU A;  3EDG A;  5D1S A;  2W12 A;  2ERQ A;  4HX3 A;  2OZR A;  1GKD A;  1K7Q A;  4WKI A;  4XCT A;  3TS4 A;  1XFU A;  2DW2 A;  3LUN A;  4L63 A;  3E8R A;  3Q2G A;  3WV3 A;  1R55 A;  3DPE A;  1IAB A;  3F19 A;  3DTI A;  3DSL A;  2Y6C A;  4PKS A;  1HTD A;  1QUA A;  3KME A;  3UVC A;  3KRY A;  4GR8 A;  4H49 A;  2X7M A;  2K2G A;  1AYK A;  1G49 A;  1XFZ A;  1JAN A;  3AIG A;  5H8X A;  2E2D A;  3B92 A;  2MZH A;  1HV5 A;  2OVX A;  2O36 A;  4DV8 A;  1D8F A;  1SMP A;  1K7G A;  1RMZ A;  4WZV A;  3LKA A;  2DW1 A;  3F15 A;  3AYK A;  1BM6 A;  2W0D A;  3RTS A;  3Q2H A;  3NX7 A;  1PWP A;  4GR0 A;  456C A;  1ZXV A;  1EAK A;  2W15 A;  2L0R A;  3TT4 A;  1CQR A;  4QKZ A;  1PWQ A;  1YCM A;  2DDY A;  1OS9 A;  3F17 A;  1D8M A;  4DD8 A;  1G12 A;  1OS2 A;  4L7A A;  1PWW A;  3SHI A;  4IUW A;  2QPJ A;  3TSK A;  4GWN A;  4IJO A;  3ZXH A;  5I0L A;  1JAP A;  3LIR A;  4GR3 A;  3KEC A;  2AIG P;  2SRT A;  2DW0 A;  4ON1 A;  3U1R A;  1WNI A;  1HFS A;  3EWJ A;  3LUM A;  3KMC A;  1BSW A;  1I1I P;  1G9K A;  1XFV A;  4PKU A;  3HBV P;  3KHI A;  4WF6 A;  1H71 P;  1GE7 A;  1MMQ A;  2WO9 A;  3HY9 A;  4JPA A;  1BUV M;  1YP1 A;  1J7N A;  2D1N A;  3EDZ A;  3K7N A;  3LGP A;  3DWB A;  1O0T A;  3LJZ A;  1C3I A;  1B8Y A;  3B8Z A;  2PJT A;  1BZS A;  1EB6 A;  1JIW P;  4XBH A;  5B5O A;  1AKL A;  1R1J A;  3EDI A;  2FV5 A;  1UTZ A;  5BOY A;  2YIG A;  1OO9 A;  3HBU P;  4PKV A;  3N2V A;  1GE5 A;  4Q1L A;  2WO8 A;  1Q3A A;  3N2U A;  3EHX A;  2DDF A;  2I47 A;  1SLM A;  3WV2 A;  3LQB A;  1XFW A;  2YUF A;  1C7K A;  1FLS A;  3L0V A;  1QIB A;  4H30 A;  1MMP A;  1XUC A;  1Y0V A;  5D3C A;  3BA0 A;  3DTE A;  1Y93 A;  2OW2 A;  2JNP A;  1RM8 A;  4GWM A;  4R3V A;  1USN A;  4JQG A;  3LMC A;  5I4O A;  1YQY A;  1BKC E;  3WV1 A;  3F16 A;  1IAE A;  1CAQ A;  830C A;  2HU6 A;  4H84 A;  2OY4 A;  2OVZ A;  5I3M A;  4G9L A;  3CKI A;  2OW0 A;  1XUD A;  5BOT A;  1KAP P;  1XFY A;  1BKC I;  1R1I A;  4A7B A;  1I76 A;  2JT5 A;  1BUD A;  2OY2 A;  2MZI A;  1OM8 A;  2J0T A;  3HY7 A;  5CZM A;  1AF0 A;  1K7I A;  2RJP A;  5LAB A;  4WK7 A;  3B2Z A;  2USN A;  1S4B P;  4ZR5 A;  1MMB A;  5D2B A;  1ZP5 A;  1JKY A;  1QIA A;  1KUI A;  3HDB A;  1G4K A;  1JAO A;  1B3D A;  1UTT A;  2W14 A;  1UEA A;  1KBC A;  1JJ9 A;  1ZS0 A;  1XFX A;  1CIZ A;  1KUH A;  1UMT A;  1R1H A;  2CKI A;  1D7X A;  2AYK A;  3MA2 A;  3KEJ A;  2POJ A;  1R54 A;  5I12 A;  1IAD A;  1OM7 A;  3ZUK A;  1HOV A;  2MZE A;  4FXQ A;  3G42 A;  3LK8 A;  4FVL A;  4JP4 A;  4I35 A;  2JSD A;  5CUH A;  4H76 A;  1QIC A;  2XS3 A;  4AIG A;  3P1V A;  4WKE A;  5D1T A;  1PWU A;  2OI0 A;  1JAQ A;  4GQL A;  1SAT A;  2CLT A;  4L19 A;  2FV9 A;  4GUY A;  3ELM A;  5B5P A;  3LIL A;  3O2X A;  4FU4 A;  2A8H A;  3EHY A;  5BPA A;  4JIJ A;  1SRP A;  5D7W A;  4DF9 A;  2Y6D A;  1HY7 A;  2W13 A;  3LEA A;  3LQ0 A;  4A3W A;  4AUO A;  2X3B A;  2XS4 A;  4GF1 A;  3TVC A;  1JIZ A;  3VI1 A;  3F1A A;  5I2Z A;  1FBL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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