3RYWA

Crystal structure of p. vivax geranylgeranyl diphosphate synthase complexed with bph-811
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
363
structure length
358
Chain Sequence
LAFFRNMYDKYRDAFLSHLNEYSLEEEIKEHISKYYKLLFDYNCLGGKNNRGILVILIYEYVKNRINSSEWEKAACLAWCIEILQAAFLVADDIMDKGEMRRNKYCWYLLKDVETKNAVNDVLLLYNSIYKLIEIYLRNESCYVDVIATFRDATLKTIIGQHLDTNIFSDKYSEIDVNNINVPEQPVIDINMINFGVYKNIVIHKTAYYSFFLPIVCGMLLAGIAVDNLIYKKIEDISMLMGEYFQIHDDYLDIFGDSTKTGKVGSDIQNNKLTWPLIKTFELCSEPDKIKIVKNYGKNNLACVKVIDSLYEQYKIRKHYESYEKAQKAKILSAINELHHEGIEYVLKYLLEILFTGV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
molecule tags Transferase
source organism Plasmodium vivax
total genus 141
structure length 358
sequence length 363
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3rywA00
3V1XA 3TC1A 3NF2A 1YV5A 5DJVF 5DIQF 2E8WA 3VJBA 1VG7A 3WCFA 5ILJA 5ILHA 1HX9A 4NKFA 3EFQA 4P0XA 4KVIA 5E8LA 2FORA 3APZA 3PYAA 2H8OA 4KVWA 5A0JA 3SDUA 3EGTA 4JXYA 3LEEA 3N3LF 3IPIA 4EA2A 3TFNA 1JFGA 3ICKA 4F6XA 4LZ3A 5H9DA 3PDEA 3ZMBA 3N49F 2E93A 3KRAB 2E4OA 3ASXA 1V4KA 3SAEA 3P5PA 3N5JF 1WL1A 4JXNA 4RXDA 3G4DA 1KIZA 1VG4A 3WCGA 3WCAA 3LDWA 5ILIA 3WSAA 3QKCA 2QISA 3OYRA 5CG6A 3SDRA 4LLSA 5ER8A 1ZW5A 4GP2A 3ICMA 5JUZF 3WCHA 3WJNA 2Z52A 4E9UA 3M9UA 3MAVA 3P8LA 3ZL6A 3KBKA 3DYGA 2Z4ZA 5KSXF 4PVXF 4OMGA 3N0GA 2ZEVA 3KRPB 2E8XA 5IK9A 2EWGA 3LVSA 1YHKA 4N1ZF 3Q2ZA 4KQSA 2J1OA 1N21A 3VJ8A 2FTZA 4FP4A 2I19A 3S4JA 4F62A 1KIYA 4LXWA 2P1CA 3EZ3A 3TFPA 1YHLA 2ZCRA 4ZQ8A 4DZWA 3CKEA 3RBMA 4OMHA 2J1PA 2Z50A 2Z4XA 1YYSA 4RXCA 3N3DA 2E8VA 3KRAA 3TS7A 4E1EA 2OPMA 3N5HF 1YYUA 3N0FA 5AHUB 3MZVA 3Q30A 1WY0A 1RQJA 1N1BA 1EZFA 1DI1A 1HXCA 2PS6A 4L2XF 2RAHA 4DXJA 2OA6A 3WCDA 4KVDA 2Z7IA 5B0JA 5IKAA 3AE0A 2F94F 3ACXA 3ICZA 4LTVA 4RYPA 2E94A 3WJKA 4NUAA 3SDQA 4KPJA 5E8KA 5HN7A 1N20A 3KRPA 2ZY1A 3N45F 3WCIA 3N6KF 3WEGA 4K10A 4DEMF 4LFGA 4RXAA 5A0IA 3N1WF 3LZ9A 4QXSF 3VJCA 2PS8A 5IN8A 4QPFA 3M0GA 1VG6A 3KROB 2Q80A 3DYHA 5ERNA 5IVGA 3LOMA 4KUXA 4DI5A 4P0WA 5B02A 2ONHA 2Z4YA 5CG5A 1HXGA 3ZMCA 4LZCA 5EASA 3LJIA 4LIXA 5HNAA 3NPKA 3LLWA 2J5CA 4EA0A 2E8UA 2Z4WA 4PVYF 5JV2F 3NPRA 4KKMA 2AZKA 3WEKA 3V1VA 4GP1A 4OKZA 4FJQA 1N23A 4LZ0A 1UBYA 3Q1OA 1PS1A 3BNXA 2O1OA 3B7LA 4KPDA 3WSBA 2E95A 5DJRF 2OPNA 1DGPA 3AQBB 2ZCQA 2AETA 3PH7A 5IMPA 4LPHF 3G4FA 1WL2A 4LOBA 1RTRA 1YHMA 5EROA 3KRCB 5HN9A 2F7MF 1VG3A 3WE9A 1V4HA 3PKOA 2F9KF 4H5CF 2AEKA 2Q9YA 2Z4VA 4P0VA 3KROA 3UCAA 3PYBA 3WCMA 4LA5A 1VG2A 2AZJA 4XQSF 4LLTA 3LGZB 3VJDA 5JA0F 3WJOA 4EA1A 2AZLA 3W7FA 1N1ZA 3WC9A 2PS7A 2OGDA 2Q9ZA 3N46F 5I1UA 2ZEUA 2PS5A 4Q23A 3ACYA 5B03A 5IL8A 2ZCSA 3WCBA 5B0KA 3ACWA 4LFVF 1V4IA 1FPSA 3KRFB 3KB9A 3ZCDA 4KWDA 3SDVA 4MC0A 2Z7HA 3ZOUA 4F6VA 1WKZA 4JYXA 5ILZA 4GAXA 4OKMA 3NRIA 3WCEA 3DYFA 3LMDA 1HM4A 4OGUA 4KK2A 5DZ2A 5EAUA 2PS4A 3M01A 5ILYA 3M02A 3WCLA 3TFVA 4LA6A 1JFAA 3ICNA 5HN8A 1YYRA 1N22A 2VF6A 3P41A 2F89F 2Q58A 4MC3A 4NFKF 3QQVA 4H5DF 3KRCA 3VJAA 1HXAA 3P5RA 1YQ7A 4DWGA 2F8CF 3RYEA 3CP6A 2DH4A 3SDTA 3BNYA 1RQIA 3S9VA 3WEJA 3P8RA 4DHDA 3OACB 5DGSF 5B0IA 1WL0A 1YJ4A 3VJ9A 3IBAA 5AELA 4HD1A 4KQUA 3AQ0A 3OABB 4LUUA 1UBXA 4RNQA 5B0MA 5IKHA 1YYQA 5AYPA 4KQ5A 5DJPF 3WCJA 3LK5A 5DW7A 5DHIA 4JZXA 1WL3A 3WEHA 4NFJF 4KVYA 1V4JA 1WMWA 2AELA 1N24A 4LTZA 1HM7A 5DGMF 3KRFA 4WK5A 3V66A 5IL3A 2F8ZF 5ILKA 1UBWA 3WEIA 2E91A 2Z78A 5ERMA 5ILDA 4DWBA 5IM1A 3AQCB 5B0LA 2E8TA 4NFIF 3WCCA 4MC8A 5B01A 1UBVA 5DHKA 5IMIA 4UMJA 3N1VF 1YYTA 4JZBA 3ID0A 5A0KA 4N9UA 5DGNF 5EATA 3M00A 3LSNA 3WEFA 2E92A 4E9ZA 4XQTF 3ADZA 3RMGA 3LGKA 3OACA 4RXEA 5JV1F 5JV0F 3LG5A 3VJEA 2ONGA 5AFXA 5C05A 3OABA 4H5EF 5IMNA 5B00A 3RYWA 3CC9A 2F92F 4NKEA 5IK0A 3Q2QA 4LPGF 4XQRF 1V4EA 2ZCOA 5E8HA 2E90A 4GA3A 5IK6A 4LFEA 4JVJF 4KFAA 4NG6A
chains in the Genus database with same CATH superfamily
3V1XA 3TC1A 3NF2A 1YV5A 5DJVF 5DIQF 2E8WA 3VJBA 1VG7A 3WCFA 5ILJA 5ILHA 1HX9A 4NKFA 3EFQA 4P0XA 4KVIA 5E8LA 2FORA 3APZA 3PYAA 2H8OA 4KVWA 5A0JA 3SDUA 3EGTA 4JXYA 3LEEA 3N3LF 3IPIA 4EA2A 3TFNA 1JFGA 3ICKA 4F6XA 4LZ3A 5H9DA 3PDEA 3ZMBA 3N49F 2E93A 3KRAB 2E4OA 3ASXA 1V4KA 3SAEA 3P5PA 3N5JF 1WL1A 4JXNA 4RXDA 3G4DA 1KIZA 1VG4A 3WCGA 3WCAA 3LDWA 5ILIA 3WSAA 3QKCA 2QISA 3OYRA 5CG6A 3SDRA 4LLSA 5ER8A 1ZW5A 4GP2A 3ICMA 5JUZF 3WCHA 3WJNA 2Z52A 4E9UA 3M9UA 3MAVA 3P8LA 3ZL6A 3KBKA 3DYGA 2Z4ZA 5KSXF 4PVXF 4OMGA 3N0GA 2ZEVA 3KRPB 2E8XA 5IK9A 2EWGA 3LVSA 1YHKA 4N1ZF 3Q2ZA 4KQSA 2J1OA 1N21A 3VJ8A 2FTZA 4FP4A 2I19A 3S4JA 4F62A 1KIYA 4LXWA 2P1CA 3EZ3A 3TFPA 1YHLA 2ZCRA 4ZQ8A 4DZWA 3CKEA 3RBMA 4OMHA 2J1PA 2Z50A 2Z4XA 1YYSA 4RXCA 3N3DA 2E8VA 3KRAA 3TS7A 4E1EA 2OPMA 3N5HF 1YYUA 3N0FA 5AHUB 3MZVA 3Q30A 1WY0A 1RQJA 1N1BA 1EZFA 1DI1A 1HXCA 2PS6A 4L2XF 2RAHA 4DXJA 2OA6A 3WCDA 4KVDA 2Z7IA 5B0JA 5IKAA 3AE0A 2F94F 3ACXA 3ICZA 4LTVA 4RYPA 2E94A 3WJKA 4NUAA 3SDQA 4KPJA 5E8KA 5HN7A 1N20A 3KRPA 2ZY1A 3N45F 3WCIA 3N6KF 3WEGA 4K10A 4DEMF 4LFGA 4RXAA 5A0IA 3N1WF 3LZ9A 4QXSF 3VJCA 2PS8A 5IN8A 4QPFA 3M0GA 1VG6A 3KROB 2Q80A 3DYHA 5ERNA 5IVGA 3LOMA 4KUXA 4DI5A 4P0WA 5B02A 2ONHA 2Z4YA 5CG5A 1HXGA 3ZMCA 4LZCA 5EASA 3LJIA 4LIXA 5HNAA 3NPKA 3LLWA 2J5CA 4EA0A 2E8UA 2Z4WA 4PVYF 5JV2F 3NPRA 4KKMA 2AZKA 3WEKA 3V1VA 4GP1A 4OKZA 4FJQA 1N23A 4LZ0A 1UBYA 3Q1OA 1PS1A 3BNXA 2O1OA 3B7LA 4KPDA 3WSBA 2E95A 5DJRF 2OPNA 1DGPA 3AQBB 2ZCQA 2AETA 3PH7A 5IMPA 4LPHF 3G4FA 1WL2A 4LOBA 1RTRA 1YHMA 5EROA 3KRCB 5HN9A 2F7MF 1VG3A 3WE9A 1V4HA 3PKOA 2F9KF 4H5CF 2AEKA 2Q9YA 2Z4VA 4P0VA 3KROA 3UCAA 3PYBA 3WCMA 4LA5A 1VG2A 2AZJA 4XQSF 4LLTA 3LGZB 3VJDA 5JA0F 3WJOA 4EA1A 2AZLA 3W7FA 1N1ZA 3WC9A 2PS7A 2OGDA 2Q9ZA 3N46F 5I1UA 2ZEUA 2PS5A 4Q23A 3ACYA 5B03A 5IL8A 2ZCSA 3WCBA 5B0KA 3ACWA 4LFVF 1V4IA 1FPSA 3KRFB 3KB9A 3ZCDA 4KWDA 3SDVA 4MC0A 2Z7HA 3ZOUA 4F6VA 1WKZA 4JYXA 5ILZA 4GAXA 4OKMA 3NRIA 3WCEA 3DYFA 3LMDA 1HM4A 4OGUA 4KK2A 5DZ2A 5EAUA 2PS4A 3M01A 5ILYA 3M02A 3WCLA 3TFVA 4LA6A 1JFAA 3ICNA 5HN8A 1YYRA 1N22A 2VF6A 3P41A 2F89F 2Q58A 4MC3A 4NFKF 3QQVA 4H5DF 3KRCA 3VJAA 1HXAA 3P5RA 1YQ7A 4DWGA 2F8CF 3RYEA 3CP6A 2DH4A 3SDTA 3BNYA 1RQIA 3S9VA 3WEJA 3P8RA 4DHDA 3OACB 5DGSF 5B0IA 1WL0A 1YJ4A 3VJ9A 3IBAA 5AELA 4HD1A 4KQUA 3AQ0A 3OABB 4LUUA 1UBXA 4RNQA 5B0MA 5IKHA 1YYQA 5AYPA 4KQ5A 5DJPF 3WCJA 3LK5A 5DW7A 5DHIA 4JZXA 1WL3A 3WEHA 4NFJF 4KVYA 1V4JA 1WMWA 2AELA 1N24A 4LTZA 1HM7A 5DGMF 3KRFA 4WK5A 3V66A 5IL3A 2F8ZF 5ILKA 1UBWA 3WEIA 2E91A 2Z78A 5ERMA 5ILDA 4DWBA 5IM1A 3AQCB 5B0LA 2E8TA 4NFIF 3WCCA 4MC8A 5B01A 1UBVA 5DHKA 5IMIA 4UMJA 3N1VF 1YYTA 4JZBA 3ID0A 5A0KA 4N9UA 5DGNF 5EATA 3M00A 3LSNA 3WEFA 2E92A 4E9ZA 4XQTF 3ADZA 3RMGA 3LGKA 3OACA 4RXEA 5JV1F 5JV0F 3LG5A 3VJEA 2ONGA 5AFXA 5C05A 3OABA 4H5EF 5IMNA 5B00A 3RYWA 3CC9A 2F92F 4NKEA 5IK0A 3Q2QA 4LPGF 4XQRF 1V4EA 2ZCOA 5E8HA 2E90A 4GA3A 5IK6A 4LFEA 4JVJF 4KFAA 4NG6A
chains in the Genus database with same CATH topology
3V1XA 3TC1A 3NF2A 1YV5A 5DJVF 5DIQF 2E8WA 3VJBA 1VG7A 3WCFA 5ILJA 5ILHA 1HX9A 4NKFA 3EFQA 4P0XA 4KVIA 5E8LA 2FORA 3APZA 3PYAA 2H8OA 4KVWA 5A0JA 3SDUA 3EGTA 4JXYA 3LEEA 3N3LF 3IPIA 4EA2A 3TFNA 1JFGA 3ICKA 4F6XA 4LZ3A 5H9DA 3PDEA 3ZMBA 3N49F 2E93A 3KRAB 2E4OA 3ASXA 1V4KA 3SAEA 3P5PA 3N5JF 1WL1A 4JXNA 4RXDA 3G4DA 1KIZA 1VG4A 3WCGA 3WCAA 3LDWA 5ILIA 3WSAA 3QKCA 2QISA 3OYRA 5CG6A 3SDRA 4LLSA 5ER8A 1ZW5A 4GP2A 3ICMA 5JUZF 3WCHA 3WJNA 2Z52A 4E9UA 3M9UA 3MAVA 3P8LA 3ZL6A 3KBKA 3DYGA 2Z4ZA 5KSXF 4PVXF 4OMGA 3N0GA 2ZEVA 3KRPB 2E8XA 5IK9A 2EWGA 3LVSA 1YHKA 4N1ZF 3Q2ZA 4KQSA 2J1OA 1N21A 3VJ8A 2FTZA 4FP4A 2I19A 3S4JA 4F62A 1KIYA 4LXWA 2P1CA 3EZ3A 3TFPA 1YHLA 2ZCRA 4ZQ8A 4DZWA 3CKEA 3RBMA 4OMHA 2J1PA 2Z50A 2Z4XA 1YYSA 4RXCA 3N3DA 2E8VA 3KRAA 3TS7A 4E1EA 2OPMA 3N5HF 1YYUA 3N0FA 5AHUB 3MZVA 3Q30A 1WY0A 1RQJA 1N1BA 1EZFA 1DI1A 1HXCA 2PS6A 4L2XF 2RAHA 4DXJA 2OA6A 3WCDA 4KVDA 2Z7IA 5B0JA 5IKAA 3AE0A 2F94F 3ACXA 3ICZA 4LTVA 4RYPA 2E94A 3WJKA 4NUAA 3SDQA 4KPJA 5E8KA 5HN7A 1N20A 3KRPA 2ZY1A 3N45F 3WCIA 3N6KF 3WEGA 4K10A 4DEMF 4LFGA 4RXAA 5A0IA 3N1WF 3LZ9A 4QXSF 3VJCA 2PS8A 5IN8A 4QPFA 3M0GA 1VG6A 3KROB 2Q80A 3DYHA 5ERNA 5IVGA 3LOMA 4KUXA 4DI5A 4P0WA 5B02A 2ONHA 2Z4YA 5CG5A 1HXGA 3ZMCA 4LZCA 5EASA 3LJIA 4LIXA 5HNAA 3NPKA 3LLWA 2J5CA 4EA0A 2E8UA 2Z4WA 4PVYF 5JV2F 3NPRA 4KKMA 2AZKA 3WEKA 3V1VA 4GP1A 4OKZA 4FJQA 1N23A 4LZ0A 1UBYA 3Q1OA 1PS1A 3BNXA 2O1OA 3B7LA 4KPDA 3WSBA 2E95A 5DJRF 2OPNA 1DGPA 3AQBB 2ZCQA 2AETA 3PH7A 5IMPA 4LPHF 3G4FA 1WL2A 4LOBA 1RTRA 1YHMA 5EROA 3KRCB 5HN9A 2F7MF 1VG3A 3WE9A 1V4HA 3PKOA 2F9KF 4H5CF 2AEKA 2Q9YA 2Z4VA 4P0VA 3KROA 3UCAA 3PYBA 3WCMA 4LA5A 1VG2A 2AZJA 4XQSF 4LLTA 3LGZB 3VJDA 5JA0F 3WJOA 4EA1A 2AZLA 3W7FA 1N1ZA 3WC9A 2PS7A 2OGDA 2Q9ZA 3N46F 5I1UA 2ZEUA 2PS5A 4Q23A 3ACYA 5B03A 5IL8A 2ZCSA 3WCBA 5B0KA 3ACWA 4LFVF 1V4IA 1FPSA 3KRFB 3KB9A 3ZCDA 4KWDA 3SDVA 4MC0A 2Z7HA 3ZOUA 4F6VA 1WKZA 4JYXA 5ILZA 4GAXA 4OKMA 3NRIA 3WCEA 3DYFA 3LMDA 1HM4A 4OGUA 4KK2A 5DZ2A 5EAUA 2PS4A 3M01A 5ILYA 3M02A 3WCLA 3TFVA 4LA6A 1JFAA 3ICNA 5HN8A 1YYRA 1N22A 2VF6A 3P41A 2F89F 2Q58A 4MC3A 4NFKF 3QQVA 4H5DF 3KRCA 3VJAA 1HXAA 3P5RA 1YQ7A 4DWGA 2F8CF 3RYEA 3CP6A 2DH4A 3SDTA 3BNYA 1RQIA 3S9VA 3WEJA 3P8RA 4DHDA 3OACB 5DGSF 5B0IA 1WL0A 1YJ4A 3VJ9A 3IBAA 5AELA 4HD1A 4KQUA 3AQ0A 3OABB 4LUUA 1UBXA 4RNQA 5B0MA 5IKHA 1YYQA 5AYPA 4KQ5A 5DJPF 3WCJA 3LK5A 5DW7A 5DHIA 4JZXA 1WL3A 3WEHA 4NFJF 4KVYA 1V4JA 1WMWA 2AELA 1N24A 4LTZA 1HM7A 5DGMF 3KRFA 4WK5A 3V66A 5IL3A 2F8ZF 5ILKA 1UBWA 3WEIA 2E91A 2Z78A 5ERMA 5ILDA 4DWBA 5IM1A 3AQCB 5B0LA 2E8TA 4NFIF 3WCCA 4MC8A 5B01A 1UBVA 5DHKA 5IMIA 4UMJA 3N1VF 1YYTA 4JZBA 3ID0A 5A0KA 4N9UA 5DGNF 5EATA 3M00A 3LSNA 3WEFA 2E92A 4E9ZA 4XQTF 3ADZA 3RMGA 3LGKA 3OACA 4RXEA 5JV1F 5JV0F 3LG5A 3VJEA 2ONGA 5AFXA 5C05A 3OABA 4H5EF 5IMNA 5B00A 3RYWA 3CC9A 2F92F 4NKEA 5IK0A 3Q2QA 4LPGF 4XQRF 1V4EA 2ZCOA 5E8HA 2E90A 4GA3A 5IK6A 4LFEA 4JVJF 4KFAA 4NG6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V1X A;  3TC1 A;  3NF2 A;  1YV5 A;  5DJV F;  5DIQ F;  2E8W A;  3VJB A;  1VG7 A;  3WCF A;  5ILJ A;  5ILH A;  1HX9 A;  4NKF A;  3EFQ A;  4P0X A;  4KVI A;  5E8L A;  2FOR A;  3APZ A;  3PYA A;  2H8O A;  4KVW A;  5A0J A;  3SDU A;  3EGT A;  4JXY A;  3LEE A;  3N3L F;  3IPI A;  4EA2 A;  3TFN A;  1JFG A;  3ICK A;  4F6X A;  4LZ3 A;  5H9D A;  3PDE A;  3ZMB A;  3N49 F;  2E93 A;  3KRA B;  2E4O A;  3ASX A;  1V4K A;  3SAE A;  3P5P A;  3N5J F;  1WL1 A;  4JXN A;  4RXD A;  3G4D A;  1KIZ A;  1VG4 A;  3WCG A;  3WCA A;  3LDW A;  5ILI A;  3WSA A;  3QKC A;  2QIS A;  3OYR A;  5CG6 A;  3SDR A;  4LLS A;  5ER8 A;  1ZW5 A;  4GP2 A;  3ICM A;  5JUZ F;  3WCH A;  3WJN A;  2Z52 A;  4E9U A;  3M9U A;  3MAV A;  3P8L A;  3ZL6 A;  3KBK A;  3DYG A;  2Z4Z A;  5KSX F;  4PVX F;  4OMG A;  3N0G A;  2ZEV A;  3KRP B;  2E8X A;  5IK9 A;  2EWG A;  3LVS A;  1YHK A;  4N1Z F;  3Q2Z A;  4KQS A;  2J1O A;  1N21 A;  3VJ8 A;  2FTZ A;  4FP4 A;  2I19 A;  3S4J A;  4F62 A;  1KIY A;  4LXW A;  2P1C A;  3EZ3 A;  3TFP A;  1YHL A;  2ZCR A;  4ZQ8 A;  4DZW A;  3CKE A;  3RBM A;  4OMH A;  2J1P A;  2Z50 A;  2Z4X A;  1YYS A;  4RXC A;  3N3D A;  2E8V A;  3KRA A;  3TS7 A;  4E1E A;  2OPM A;  3N5H F;  1YYU A;  3N0F A;  5AHU B;  3MZV A;  3Q30 A;  1WY0 A;  1RQJ A;  1N1B A;  1EZF A;  1DI1 A;  1HXC A;  2PS6 A;  4L2X F;  2RAH A;  4DXJ A;  2OA6 A;  3WCD A;  4KVD A;  2Z7I A;  5B0J A;  5IKA A;  3AE0 A;  2F94 F;  3ACX A;  3ICZ A;  4LTV A;  4RYP A;  2E94 A;  3WJK A;  4NUA A;  3SDQ A;  4KPJ A;  5E8K A;  5HN7 A;  1N20 A;  3KRP A;  2ZY1 A;  3N45 F;  3WCI A;  3N6K F;  3WEG A;  4K10 A;  4DEM F;  4LFG A;  4RXA A;  5A0I A;  3N1W F;  3LZ9 A;  4QXS F;  3VJC A;  2PS8 A;  5IN8 A;  4QPF A;  3M0G A;  1VG6 A;  3KRO B;  2Q80 A;  3DYH A;  5ERN A;  5IVG A;  3LOM A;  4KUX A;  4DI5 A;  4P0W A;  5B02 A;  2ONH A;  2Z4Y A;  5CG5 A;  1HXG A;  3ZMC A;  4LZC A;  5EAS A;  3LJI A;  4LIX A;  5HNA A;  3NPK A;  3LLW A;  2J5C A;  4EA0 A;  2E8U A;  2Z4W A;  4PVY F;  5JV2 F;  3NPR A;  4KKM A;  2AZK A;  3WEK A;  3V1V A;  4GP1 A;  4OKZ A;  4FJQ A;  1N23 A;  4LZ0 A;  1UBY A;  3Q1O A;  1PS1 A;  3BNX A;  2O1O A;  3B7L A;  4KPD A;  3WSB A;  2E95 A;  5DJR F;  2OPN A;  1DGP A;  3AQB B;  2ZCQ A;  2AET A;  3PH7 A;  5IMP A;  4LPH F;  3G4F A;  1WL2 A;  4LOB A;  1RTR A;  1YHM A;  5ERO A;  3KRC B;  5HN9 A;  2F7M F;  1VG3 A;  3WE9 A;  1V4H A;  3PKO A;  2F9K F;  4H5C F;  2AEK A;  2Q9Y A;  2Z4V A;  4P0V A;  3KRO A;  3UCA A;  3PYB A;  3WCM A;  4LA5 A;  1VG2 A;  2AZJ A;  4XQS F;  4LLT A;  3LGZ B;  3VJD A;  5JA0 F;  3WJO A;  4EA1 A;  2AZL A;  3W7F A;  1N1Z A;  3WC9 A;  2PS7 A;  2OGD A;  2Q9Z A;  3N46 F;  5I1U A;  2ZEU A;  2PS5 A;  4Q23 A;  3ACY A;  5B03 A;  5IL8 A;  2ZCS A;  3WCB A;  5B0K A;  3ACW A;  4LFV F;  1V4I A;  1FPS A;  3KRF B;  3KB9 A;  3ZCD A;  4KWD A;  3SDV A;  4MC0 A;  2Z7H A;  3ZOU A;  4F6V A;  1WKZ A;  4JYX A;  5ILZ A;  4GAX A;  4OKM A;  3NRI A;  3WCE A;  3DYF A;  3LMD A;  1HM4 A;  4OGU A;  4KK2 A;  5DZ2 A;  5EAU A;  2PS4 A;  3M01 A;  5ILY A;  3M02 A;  3WCL A;  3TFV A;  4LA6 A;  1JFA A;  3ICN A;  5HN8 A;  1YYR A;  1N22 A;  2VF6 A;  3P41 A;  2F89 F;  2Q58 A;  4MC3 A;  4NFK F;  3QQV A;  4H5D F;  3KRC A;  3VJA A;  1HXA A;  3P5R A;  1YQ7 A;  4DWG A;  2F8C F;  3RYE A;  3CP6 A;  2DH4 A;  3SDT A;  3BNY A;  1RQI A;  3S9V A;  3WEJ A;  3P8R A;  4DHD A;  3OAC B;  5DGS F;  5B0I A;  1WL0 A;  1YJ4 A;  3VJ9 A;  3IBA A;  5AEL A;  4HD1 A;  4KQU A;  3AQ0 A;  3OAB B;  4LUU A;  1UBX A;  4RNQ A;  5B0M A;  5IKH A;  1YYQ A;  5AYP A;  4KQ5 A;  5DJP F;  3WCJ A;  3LK5 A;  5DW7 A;  5DHI A;  4JZX A;  1WL3 A;  3WEH A;  4NFJ F;  4KVY A;  1V4J A;  1WMW A;  2AEL A;  1N24 A;  4LTZ A;  1HM7 A;  5DGM F;  3KRF A;  4WK5 A;  3V66 A;  5IL3 A;  2F8Z F;  5ILK A;  1UBW A;  3WEI A;  2E91 A;  2Z78 A;  5ERM A;  5ILD A;  4DWB A;  5IM1 A;  3AQC B;  5B0L A;  2E8T A;  4NFI F;  3WCC A;  4MC8 A;  5B01 A;  1UBV A;  5DHK A;  5IMI A;  4UMJ A;  3N1V F;  1YYT A;  4JZB A;  3ID0 A;  5A0K A;  4N9U A;  5DGN F;  5EAT A;  3M00 A;  3LSN A;  3WEF A;  2E92 A;  4E9Z A;  4XQT F;  3ADZ A;  3RMG A;  3LGK A;  3OAC A;  4RXE A;  5JV1 F;  5JV0 F;  3LG5 A;  3VJE A;  2ONG A;  5AFX A;  5C05 A;  3OAB A;  4H5E F;  5IMN A;  5B00 A;  3RYW A;  3CC9 A;  2F92 F;  4NKE A;  5IK0 A;  3Q2Q A;  4LPG F;  4XQR F;  1V4E A;  2ZCO A;  5E8H A;  2E90 A;  4GA3 A;  5IK6 A;  4LFE A;  4JVJ F;  4KFA A;  4NG6 A; 
#chains in the Genus database with same CATH topology
 3V1X A;  3TC1 A;  3NF2 A;  1YV5 A;  5DJV F;  5DIQ F;  2E8W A;  3VJB A;  1VG7 A;  3WCF A;  5ILJ A;  5ILH A;  1HX9 A;  4NKF A;  3EFQ A;  4P0X A;  4KVI A;  5E8L A;  2FOR A;  3APZ A;  3PYA A;  2H8O A;  4KVW A;  5A0J A;  3SDU A;  3EGT A;  4JXY A;  3LEE A;  3N3L F;  3IPI A;  4EA2 A;  3TFN A;  1JFG A;  3ICK A;  4F6X A;  4LZ3 A;  5H9D A;  3PDE A;  3ZMB A;  3N49 F;  2E93 A;  3KRA B;  2E4O A;  3ASX A;  1V4K A;  3SAE A;  3P5P A;  3N5J F;  1WL1 A;  4JXN A;  4RXD A;  3G4D A;  1KIZ A;  1VG4 A;  3WCG A;  3WCA A;  3LDW A;  5ILI A;  3WSA A;  3QKC A;  2QIS A;  3OYR A;  5CG6 A;  3SDR A;  4LLS A;  5ER8 A;  1ZW5 A;  4GP2 A;  3ICM A;  5JUZ F;  3WCH A;  3WJN A;  2Z52 A;  4E9U A;  3M9U A;  3MAV A;  3P8L A;  3ZL6 A;  3KBK A;  3DYG A;  2Z4Z A;  5KSX F;  4PVX F;  4OMG A;  3N0G A;  2ZEV A;  3KRP B;  2E8X A;  5IK9 A;  2EWG A;  3LVS A;  1YHK A;  4N1Z F;  3Q2Z A;  4KQS A;  2J1O A;  1N21 A;  3VJ8 A;  2FTZ A;  4FP4 A;  2I19 A;  3S4J A;  4F62 A;  1KIY A;  4LXW A;  2P1C A;  3EZ3 A;  3TFP A;  1YHL A;  2ZCR A;  4ZQ8 A;  4DZW A;  3CKE A;  3RBM A;  4OMH A;  2J1P A;  2Z50 A;  2Z4X A;  1YYS A;  4RXC A;  3N3D A;  2E8V A;  3KRA A;  3TS7 A;  4E1E A;  2OPM A;  3N5H F;  1YYU A;  3N0F A;  5AHU B;  3MZV A;  3Q30 A;  1WY0 A;  1RQJ A;  1N1B A;  1EZF A;  1DI1 A;  1HXC A;  2PS6 A;  4L2X F;  2RAH A;  4DXJ A;  2OA6 A;  3WCD A;  4KVD A;  2Z7I A;  5B0J A;  5IKA A;  3AE0 A;  2F94 F;  3ACX A;  3ICZ A;  4LTV A;  4RYP A;  2E94 A;  3WJK A;  4NUA A;  3SDQ A;  4KPJ A;  5E8K A;  5HN7 A;  1N20 A;  3KRP A;  2ZY1 A;  3N45 F;  3WCI A;  3N6K F;  3WEG A;  4K10 A;  4DEM F;  4LFG A;  4RXA A;  5A0I A;  3N1W F;  3LZ9 A;  4QXS F;  3VJC A;  2PS8 A;  5IN8 A;  4QPF A;  3M0G A;  1VG6 A;  3KRO B;  2Q80 A;  3DYH A;  5ERN A;  5IVG A;  3LOM A;  4KUX A;  4DI5 A;  4P0W A;  5B02 A;  2ONH A;  2Z4Y A;  5CG5 A;  1HXG A;  3ZMC A;  4LZC A;  5EAS A;  3LJI A;  4LIX A;  5HNA A;  3NPK A;  3LLW A;  2J5C A;  4EA0 A;  2E8U A;  2Z4W A;  4PVY F;  5JV2 F;  3NPR A;  4KKM A;  2AZK A;  3WEK A;  3V1V A;  4GP1 A;  4OKZ A;  4FJQ A;  1N23 A;  4LZ0 A;  1UBY A;  3Q1O A;  1PS1 A;  3BNX A;  2O1O A;  3B7L A;  4KPD A;  3WSB A;  2E95 A;  5DJR F;  2OPN A;  1DGP A;  3AQB B;  2ZCQ A;  2AET A;  3PH7 A;  5IMP A;  4LPH F;  3G4F A;  1WL2 A;  4LOB A;  1RTR A;  1YHM A;  5ERO A;  3KRC B;  5HN9 A;  2F7M F;  1VG3 A;  3WE9 A;  1V4H A;  3PKO A;  2F9K F;  4H5C F;  2AEK A;  2Q9Y A;  2Z4V A;  4P0V A;  3KRO A;  3UCA A;  3PYB A;  3WCM A;  4LA5 A;  1VG2 A;  2AZJ A;  4XQS F;  4LLT A;  3LGZ B;  3VJD A;  5JA0 F;  3WJO A;  4EA1 A;  2AZL A;  3W7F A;  1N1Z A;  3WC9 A;  2PS7 A;  2OGD A;  2Q9Z A;  3N46 F;  5I1U A;  2ZEU A;  2PS5 A;  4Q23 A;  3ACY A;  5B03 A;  5IL8 A;  2ZCS A;  3WCB A;  5B0K A;  3ACW A;  4LFV F;  1V4I A;  1FPS A;  3KRF B;  3KB9 A;  3ZCD A;  4KWD A;  3SDV A;  4MC0 A;  2Z7H A;  3ZOU A;  4F6V A;  1WKZ A;  4JYX A;  5ILZ A;  4GAX A;  4OKM A;  3NRI A;  3WCE A;  3DYF A;  3LMD A;  1HM4 A;  4OGU A;  4KK2 A;  5DZ2 A;  5EAU A;  2PS4 A;  3M01 A;  5ILY A;  3M02 A;  3WCL A;  3TFV A;  4LA6 A;  1JFA A;  3ICN A;  5HN8 A;  1YYR A;  1N22 A;  2VF6 A;  3P41 A;  2F89 F;  2Q58 A;  4MC3 A;  4NFK F;  3QQV A;  4H5D F;  3KRC A;  3VJA A;  1HXA A;  3P5R A;  1YQ7 A;  4DWG A;  2F8C F;  3RYE A;  3CP6 A;  2DH4 A;  3SDT A;  3BNY A;  1RQI A;  3S9V A;  3WEJ A;  3P8R A;  4DHD A;  3OAC B;  5DGS F;  5B0I A;  1WL0 A;  1YJ4 A;  3VJ9 A;  3IBA A;  5AEL A;  4HD1 A;  4KQU A;  3AQ0 A;  3OAB B;  4LUU A;  1UBX A;  4RNQ A;  5B0M A;  5IKH A;  1YYQ A;  5AYP A;  4KQ5 A;  5DJP F;  3WCJ A;  3LK5 A;  5DW7 A;  5DHI A;  4JZX A;  1WL3 A;  3WEH A;  4NFJ F;  4KVY A;  1V4J A;  1WMW A;  2AEL A;  1N24 A;  4LTZ A;  1HM7 A;  5DGM F;  3KRF A;  4WK5 A;  3V66 A;  5IL3 A;  2F8Z F;  5ILK A;  1UBW A;  3WEI A;  2E91 A;  2Z78 A;  5ERM A;  5ILD A;  4DWB A;  5IM1 A;  3AQC B;  5B0L A;  2E8T A;  4NFI F;  3WCC A;  4MC8 A;  5B01 A;  1UBV A;  5DHK A;  5IMI A;  4UMJ A;  3N1V F;  1YYT A;  4JZB A;  3ID0 A;  5A0K A;  4N9U A;  5DGN F;  5EAT A;  3M00 A;  3LSN A;  3WEF A;  2E92 A;  4E9Z A;  4XQT F;  3ADZ A;  3RMG A;  3LGK A;  3OAC A;  4RXE A;  5JV1 F;  5JV0 F;  3LG5 A;  3VJE A;  2ONG A;  5AFX A;  5C05 A;  3OAB A;  4H5E F;  5IMN A;  5B00 A;  3RYW A;  3CC9 A;  2F92 F;  4NKE A;  5IK0 A;  3Q2Q A;  4LPG F;  4XQR F;  1V4E A;  2ZCO A;  5E8H A;  2E90 A;  4GA3 A;  5IK6 A;  4LFE A;  4JVJ F;  4KFA A;  4NG6 A; 
#chains in the Genus database with same CATH homology
 3V1X A;  3TC1 A;  3NF2 A;  1YV5 A;  5DJV F;  5DIQ F;  2E8W A;  3VJB A;  1VG7 A;  3WCF A;  5ILJ A;  5ILH A;  1HX9 A;  4NKF A;  3EFQ A;  4P0X A;  4KVI A;  5E8L A;  2FOR A;  3APZ A;  3PYA A;  2H8O A;  4KVW A;  5A0J A;  3SDU A;  3EGT A;  4JXY A;  3LEE A;  3N3L F;  3IPI A;  4EA2 A;  3TFN A;  1JFG A;  3ICK A;  4F6X A;  4LZ3 A;  5H9D A;  3PDE A;  3ZMB A;  3N49 F;  2E93 A;  3KRA B;  2E4O A;  3ASX A;  1V4K A;  3SAE A;  3P5P A;  3N5J F;  1WL1 A;  4JXN A;  4RXD A;  3G4D A;  1KIZ A;  1VG4 A;  3WCG A;  3WCA A;  3LDW A;  5ILI A;  3WSA A;  3QKC A;  2QIS A;  3OYR A;  5CG6 A;  3SDR A;  4LLS A;  5ER8 A;  1ZW5 A;  4GP2 A;  3ICM A;  5JUZ F;  3WCH A;  3WJN A;  2Z52 A;  4E9U A;  3M9U A;  3MAV A;  3P8L A;  3ZL6 A;  3KBK A;  3DYG A;  2Z4Z A;  5KSX F;  4PVX F;  4OMG A;  3N0G A;  2ZEV A;  3KRP B;  2E8X A;  5IK9 A;  2EWG A;  3LVS A;  1YHK A;  4N1Z F;  3Q2Z A;  4KQS A;  2J1O A;  1N21 A;  3VJ8 A;  2FTZ A;  4FP4 A;  2I19 A;  3S4J A;  4F62 A;  1KIY A;  4LXW A;  2P1C A;  3EZ3 A;  3TFP A;  1YHL A;  2ZCR A;  4ZQ8 A;  4DZW A;  3CKE A;  3RBM A;  4OMH A;  2J1P A;  2Z50 A;  2Z4X A;  1YYS A;  4RXC A;  3N3D A;  2E8V A;  3KRA A;  3TS7 A;  4E1E A;  2OPM A;  3N5H F;  1YYU A;  3N0F A;  5AHU B;  3MZV A;  3Q30 A;  1WY0 A;  1RQJ A;  1N1B A;  1EZF A;  1DI1 A;  1HXC A;  2PS6 A;  4L2X F;  2RAH A;  4DXJ A;  2OA6 A;  3WCD A;  4KVD A;  2Z7I A;  5B0J A;  5IKA A;  3AE0 A;  2F94 F;  3ACX A;  3ICZ A;  4LTV A;  4RYP A;  2E94 A;  3WJK A;  4NUA A;  3SDQ A;  4KPJ A;  5E8K A;  5HN7 A;  1N20 A;  3KRP A;  2ZY1 A;  3N45 F;  3WCI A;  3N6K F;  3WEG A;  4K10 A;  4DEM F;  4LFG A;  4RXA A;  5A0I A;  3N1W F;  3LZ9 A;  4QXS F;  3VJC A;  2PS8 A;  5IN8 A;  4QPF A;  3M0G A;  1VG6 A;  3KRO B;  2Q80 A;  3DYH A;  5ERN A;  5IVG A;  3LOM A;  4KUX A;  4DI5 A;  4P0W A;  5B02 A;  2ONH A;  2Z4Y A;  5CG5 A;  1HXG A;  3ZMC A;  4LZC A;  5EAS A;  3LJI A;  4LIX A;  5HNA A;  3NPK A;  3LLW A;  2J5C A;  4EA0 A;  2E8U A;  2Z4W A;  4PVY F;  5JV2 F;  3NPR A;  4KKM A;  2AZK A;  3WEK A;  3V1V A;  4GP1 A;  4OKZ A;  4FJQ A;  1N23 A;  4LZ0 A;  1UBY A;  3Q1O A;  1PS1 A;  3BNX A;  2O1O A;  3B7L A;  4KPD A;  3WSB A;  2E95 A;  5DJR F;  2OPN A;  1DGP A;  3AQB B;  2ZCQ A;  2AET A;  3PH7 A;  5IMP A;  4LPH F;  3G4F A;  1WL2 A;  4LOB A;  1RTR A;  1YHM A;  5ERO A;  3KRC B;  5HN9 A;  2F7M F;  1VG3 A;  3WE9 A;  1V4H A;  3PKO A;  2F9K F;  4H5C F;  2AEK A;  2Q9Y A;  2Z4V A;  4P0V A;  3KRO A;  3UCA A;  3PYB A;  3WCM A;  4LA5 A;  1VG2 A;  2AZJ A;  4XQS F;  4LLT A;  3LGZ B;  3VJD A;  5JA0 F;  3WJO A;  4EA1 A;  2AZL A;  3W7F A;  1N1Z A;  3WC9 A;  2PS7 A;  2OGD A;  2Q9Z A;  3N46 F;  5I1U A;  2ZEU A;  2PS5 A;  4Q23 A;  3ACY A;  5B03 A;  5IL8 A;  2ZCS A;  3WCB A;  5B0K A;  3ACW A;  4LFV F;  1V4I A;  1FPS A;  3KRF B;  3KB9 A;  3ZCD A;  4KWD A;  3SDV A;  4MC0 A;  2Z7H A;  3ZOU A;  4F6V A;  1WKZ A;  4JYX A;  5ILZ A;  4GAX A;  4OKM A;  3NRI A;  3WCE A;  3DYF A;  3LMD A;  1HM4 A;  4OGU A;  4KK2 A;  5DZ2 A;  5EAU A;  2PS4 A;  3M01 A;  5ILY A;  3M02 A;  3WCL A;  3TFV A;  4LA6 A;  1JFA A;  3ICN A;  5HN8 A;  1YYR A;  1N22 A;  2VF6 A;  3P41 A;  2F89 F;  2Q58 A;  4MC3 A;  4NFK F;  3QQV A;  4H5D F;  3KRC A;  3VJA A;  1HXA A;  3P5R A;  1YQ7 A;  4DWG A;  2F8C F;  3RYE A;  3CP6 A;  2DH4 A;  3SDT A;  3BNY A;  1RQI A;  3S9V A;  3WEJ A;  3P8R A;  4DHD A;  3OAC B;  5DGS F;  5B0I A;  1WL0 A;  1YJ4 A;  3VJ9 A;  3IBA A;  5AEL A;  4HD1 A;  4KQU A;  3AQ0 A;  3OAB B;  4LUU A;  1UBX A;  4RNQ A;  5B0M A;  5IKH A;  1YYQ A;  5AYP A;  4KQ5 A;  5DJP F;  3WCJ A;  3LK5 A;  5DW7 A;  5DHI A;  4JZX A;  1WL3 A;  3WEH A;  4NFJ F;  4KVY A;  1V4J A;  1WMW A;  2AEL A;  1N24 A;  4LTZ A;  1HM7 A;  5DGM F;  3KRF A;  4WK5 A;  3V66 A;  5IL3 A;  2F8Z F;  5ILK A;  1UBW A;  3WEI A;  2E91 A;  2Z78 A;  5ERM A;  5ILD A;  4DWB A;  5IM1 A;  3AQC B;  5B0L A;  2E8T A;  4NFI F;  3WCC A;  4MC8 A;  5B01 A;  1UBV A;  5DHK A;  5IMI A;  4UMJ A;  3N1V F;  1YYT A;  4JZB A;  3ID0 A;  5A0K A;  4N9U A;  5DGN F;  5EAT A;  3M00 A;  3LSN A;  3WEF A;  2E92 A;  4E9Z A;  4XQT F;  3ADZ A;  3RMG A;  3LGK A;  3OAC A;  4RXE A;  5JV1 F;  5JV0 F;  3LG5 A;  3VJE A;  2ONG A;  5AFX A;  5C05 A;  3OAB A;  4H5E F;  5IMN A;  5B00 A;  3RYW A;  3CC9 A;  2F92 F;  4NKE A;  5IK0 A;  3Q2Q A;  4LPG F;  4XQR F;  1V4E A;  2ZCO A;  5E8H A;  2E90 A;  4GA3 A;  5IK6 A;  4LFE A;  4JVJ F;  4KFA A;  4NG6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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