3S8ZA

Crystal structure of lrp6-e3e4
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
615
structure length
606
Chain Sequence
VPEAFLLFSRRADIRRISLETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQSGWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Low-density lipoprotein receptor-related protein 6
total genus 139
structure length 606
sequence length 615
ec nomenclature
pdb deposition date 2011-05-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00058 Ldl_recept_b Low-density lipoprotein receptor repeat class B
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.30 Mainly Beta 6 Propeller Neuraminidase TolB, C-terminal domain 3s8zA02
2.120.10.30 Mainly Beta 6 Propeller Neuraminidase TolB, C-terminal domain 3s8zA01
3I1CA 3G4HA 3S8ZA 4DG6A 2DSOA 1QBIA 2IASA 4R40A 2P4OA 3Q6TA 4GNAA 2IAPA 1PJXA 2FPBA 1CQ1A 3SRGA 3KYAA 5GX3A 5D9BA 3Q6KA 3V1SA 5D9CA 2IAOA 1C9UA 4Q1UA 1CRUA 2GVWA 3LI3A 2V91A 2HQSA 5EX7A 4GN8A 5GX2A 3KGGA 4GN7A 4O5TA 3U0SA 2W8BA 3V64C 2OJHA 3TC9A 3O4PA 1CRZA 2IAUA 1CVMA 2IVZA 4IYGA 2POOA 2IARA 4IMBA 1RWIA 2FP8A 1RWLA 3S8VA 2DG1A 1E1AA 1IJQA 5GX4A 3AMRA 4A0PA 5D9DA 5FWWA 1NPEA 2W8BB 3AMSA 2IAVA 3SOQA 3P5BL 3V65B 1POOA 1H6LA 4ZLRA 4GNCA 2IAXA 3SOBB 3G4EA 4PWZA 3FW0A 3SOVA 3FVZA 2DG0A 3WWAA 4GNBA 4HHQA 2GVVA 3DR2A 3A9GA 3HLHA 4GN9A 3SREA 5GX5A 4HW6A 2GVXA 1QLGA 2IATA 2VAQA 3S2KA 2FP9A 3A9HA 3HRPA 3E5ZA 5GX1A 2GHSA 2G8SA 3Q6PA 2IAQA 3S94A 3WW9A 1V04A 4JMLA 2FPCA 3BYCA 3DASA 3HLIA 4O5SA 1C5KA 3IAXA 2IAWA 1N7DA 2GVUA 4HHOA 3LI4A 3LI5A 1Q7FA 2QE8A 5GTQA 2ISMA
chains in the Genus database with same CATH superfamily
1MS5A 3I1CA 1ZGKA 4XJUA 3JU4A 1N1YA 1NNAA 2QWFA 2F12A 2P4OA 4FPOB 1E8VA 2YA8A 4K1JA 1IUCA 3Q6TA 4GZSA 4CPOA 5F9TA 4GNAA 3W09A 4CPYA 4D52C 4MWUA 2W5OA 2AEQA 1IVDA 1V3CA 1C9UA 1CRUA 2GVWA 2HQSA 2RKCA 2V91A 3KGGA 1F8DA 5FZJA 3SANA 2W8BA 1INXA 2XCYA 1MWEA 4BBWA 4QN6A 1MS8A 2IAUA 5FNSA 1Z4VA 1INHA 3TI3A 1RWLA 1DIMA 4WEFA 3H73A 1A4GA 3K37A 3ALXA 2SLIA 3AMSA 2IAVA 1NN2A 1H6LA 4YW4A 2ZWAA 4ZLRA 2QWCA 2SILA 3G4EA 1NMCA 1W8OA 4MWVA 3SOVA 4MZEA 4XILA 4HHQA 2XZIA 1N1TA 4FPLA 3SREA 2JKBA 3A71A 4IFJA 4M4UA 3K3AA 4N1BA 4MWLA 4FPEA 1QLGA 1BJIA 4YZ4A 1S1DA 2HT7A 3A9HA 3E5ZA 2G8SA 4FPGA 3CL0A 1Z4YA 3WW9A 1Z50A 2XZKA 3NN9A 4DGRA 2FPCA 1X2JA 2QWJA 3BYCA 1USRA 2YA5A 3DASA 4YZ3A 4YY8A 4MWYA 1MZ6A 4I00A 1EURA 4MC7A 3WN7A 4KS4A 1IVEA 1MS0A 1N1VA 4XJZA 3SLIA 1C5KA 1W8NA 4IFLX 4HIZA 4YW2A 2GVUA 2HTQA 4IQKA 3GVLA 3LI4A 3LI5A 4YW1A 4K1HA 2ISMA 1N6FA 4XE9A 3H72A 2WOZA 4L7CA 4FOWA 1MS9A 4XJAA 4XYXA 1U6DX 4DG6A 2DSOA 3ZGCA 1QBIA 2IASA 4XHXA 1INVA 4KS1A 1W0OA 2C4AA 1V0FA 2BATA 3GVJA 4ASCA 1NCAN 5HUGA 4YZ2A 1PJXA 2FPBA 4NC5A 2QWGA 3SRGA 5D9BA 3K38A 4FP2A 4XMIA 1SNTA 4SLIA 2BZDA 5D9CA 1Z4ZA 1MR5A 4K1KA 1NNCA 2VW0A 4GN7A 3U0SA 1B9SA 4X47A 4GB1A 4H53A 1WCSA 1CRZA 2VK6A 1E8UA 1USXA 4NCSA 1WCQA 2FP8A 3S8VA 1NMBN 1E1AA 4QN5A 5GX4A 4KS2A 1IVFA 3AMRA 4A0PA 1B9VA 4QN3A 1NSDA 1NPEA 4CSDA 4AH4A 3SOQA 1MS1A 2W38A 4YZ1A 4GNCA 4KS3A 1INYA 4GDJA 2YA7A 2BF6A 4B7MA 2F25A 4FPFA 3FVZA 2FHRA 1IUBA 7NN9A 5F72C 1F8EA 5B2DA 2F11A 4GNBA 4HZZA 4C1YB 2GVVA 3HLHA 2XZJA 5HUKA 2F28A 4AHAA 4GJTA 1MZ5A 1WP5A 1L7FA 2QWKA 2F24A 4D52A 1NSBA 4M4NA 4AGTA 2VW1A 2F29A 1A4QA 5EO8A 4UOUA 3CKZA 1OFZA 4WA3A 4CHBA 4GZPA 1SLLA 2FLUX 3TI6A 4FP3A 1S0JA 2AGSA 4FPKA 4MWJA 4FPCA 3HLIA 4AGIA 2IAWA 1N7DA 1W1XA 2SIMA 3BEQA 3D11A 4K1IA 2F10A 1MS4A 2H2UA 4CPMA 3B69A 1NSCA 1EUSA 2F13A 3G4HA 3D12A 3S8ZA 1N6EA 3CYEA 4XJ9A 3K36A 3TI5A 2ZZKA 4D8SA 1K32A 5JYYA 1V3EA 1NCCN 2IAPA 1V0EA 4YZ5A 1CQ1A 1INGA 5GX3A 3TI8A 2HTWA 2Z32A 5EO7A 3Q6KA 4CPLA 2QWHA 3V1SA 4FPJA 2IAOA 4IN4A 4Q1UA 3II7A 2HTUA 3NSSA 2AH2A 2BERA 1VCUA 4GN8A 5GX2A 1XOGA 3NO0A 4O5TA 4WEGA 4QN7A 3K39A 4YW3A 3SILA 3T1EA 3TICA 1Z4WA 1EUTA 5M1ZA 4WA5A 1INWA 1CVMA 2IVZA 4IYGA 2POOA 1V0ZA 1RWIA 4XJWA 1VCJA 1L7GA 2DG1A 4FZHA 4MWWA 1L7HA 2VPJA 3ADEA 2W8BB 2W5NA 2HU0A 2VSKA 3UC1A 3P5BL 1POOA 3B7EA 1IVGA 3GVKA 4FPYA 1A14N 1IVBA 1NMAN 1W21A 5H47A 1SO7A 4PWZA 4MWQA 1IVCA 1NCDN 3H6JA 3CL2A 2VSMA 2DG0A 4UF7A 4FOQA 4B7RA 4CPZA 3DR2A 3A9GA 4MWRA 4GN9A 4D52B 4M3MA 2HT8A 5B2CA 4HW6A 2GVXA 5FNQA 4X4AA 4XIKA 1V2IA 3S2KA 2FP9A 4D4UA 3HRPA 2GHSA 5FNUA 5HUNA 1N1SA 2IAQA 4MZAA 3S94A 1V04A 4XJRA 2QWDA 2QWEA 1V3BA 1S18A 4H52A 1V3DA 4B7JA 2VK5A 4IFNX 4M4VA 4O5SA 2AEPA 3IAXA 4GZXA 4ZY3A 3ALWA 4ZGCA 2YA4A 4B7QA 2QE8A 2YDTA 2ZB5A 4G3NA 4X6KA 4HZYA 4MWXA 1NNBA 3A72A 1B9TA 4FPHA 2YA6A 4KS5A 3INBA 2HTRA 4J9TA 4YW5A 4FOVA 2HU4A 2W20A 3O9JA 4R40A 4XJQA 1SUUA 4QNPA 4JF7A 1SLIA 4GEZA 4XIOA 3L6VA 4GDIA 3WDZA 4HZVA 4HZXA 3KYAA 2QWAA 3ZGDA 1DILA 1ZI0A 2CMLA 3VNHA 4B7NA 1INFA 5FNRA 5HUMA 5FZNA 2ZB6A 3LI3A 4XMAA 5EX7A 2HT5A 2A75A 1N6DA 3OPZA 3V64C 1W20A 2XN4A 2DYHA 1X2RA 2OJHA 4QN4A 3TC9A 3O4PA 4K3YA 4FOYA 2IARA 5CGJA 4IMBA 4NN9A 1W0PA 3SALA 2F27A 2B8HA 1IJQA 1E8TA 3VNGA 5D9DA 3PJQA 4C1YA 4L7DA 2H2NA 5FWWA 4MJVA 4FQ4A 4Q6KA 4X49A 3V65B 4XMBA 3TIBA 2C4LA 4MJUA 2QWIA 4FJ6A 3H71A 4WA4A 5FNTA 2IAXA 4GZOA 3SOBB 3FW0A 1KITA 4XHBA 1F8CA 4L7BA 3WWAA 4MX0A 4GZQA 5GX5A 2VWDA 1S0IA 4GZTA 2VK7A 1NCBN 2VVZA 6NN9A 4GZWA 2YDPA 2HTYA 1F8BA 2F0ZA 2IATA 1EUUA 2VAQA 5GX1A 3Q6PA 1MS3A 1XOEA 2F26A 4XJ8A 2X9MA 4JMLA 3TIAA 4FVKA 4HZWA 5NN9A 4XOGA 2QWBA 3O9KA 3TI4A 2VW2A 4CH9A 2ZW9A 2HTVA 1Z4XA 4HHOA 1Q7FA 5HX0A 4CPNA 5GTQA
chains in the Genus database with same CATH topology
3I1CA 3G4HA 3S8ZA 4DG6A 2DSOA 1QBIA 2IASA 4R40A 2P4OA 3Q6TA 4GNAA 2IAPA 1PJXA 2FPBA 1CQ1A 3SRGA 3KYAA 5GX3A 5D9BA 3Q6KA 3V1SA 5D9CA 2IAOA 1C9UA 4Q1UA 1CRUA 2GVWA 3LI3A 2V91A 2HQSA 5EX7A 4GN8A 5GX2A 3KGGA 4GN7A 4O5TA 3U0SA 2W8BA 3V64C 2OJHA 3TC9A 3O4PA 1CRZA 2IAUA 1CVMA 2IVZA 4IYGA 2POOA 2IARA 4IMBA 1RWIA 2FP8A 1RWLA 3S8VA 2DG1A 1E1AA 1IJQA 5GX4A 3AMRA 4A0PA 5D9DA 5FWWA 1NPEA 2W8BB 3AMSA 2IAVA 3SOQA 3P5BL 3V65B 1POOA 1H6LA 4ZLRA 4GNCA 2IAXA 3SOBB 3G4EA 4PWZA 3FW0A 3SOVA 3FVZA 2DG0A 3WWAA 4GNBA 4HHQA 2GVVA 3DR2A 3A9GA 3HLHA 4GN9A 3SREA 5GX5A 4HW6A 2GVXA 1QLGA 2IATA 2VAQA 3S2KA 2FP9A 3A9HA 3HRPA 3E5ZA 5GX1A 2GHSA 2G8SA 3Q6PA 2IAQA 3S94A 3WW9A 1V04A 4JMLA 2FPCA 3BYCA 3DASA 3HLIA 4O5SA 1C5KA 3IAXA 2IAWA 1N7DA 2GVUA 4HHOA 3LI4A 3LI5A 1Q7FA 2QE8A 5GTQA 2ISMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I1C A;  3G4H A;  3S8Z A;  4DG6 A;  2DSO A;  1QBI A;  2IAS A;  4R40 A;  2P4O A;  3Q6T A;  4GNA A;  2IAP A;  1PJX A;  2FPB A;  1CQ1 A;  3SRG A;  3KYA A;  5GX3 A;  5D9B A;  3Q6K A;  3V1S A;  5D9C A;  2IAO A;  1C9U A;  4Q1U A;  1CRU A;  2GVW A;  3LI3 A;  2V91 A;  2HQS A;  5EX7 A;  4GN8 A;  5GX2 A;  3KGG A;  4GN7 A;  4O5T A;  3U0S A;  2W8B A;  3V64 C;  2OJH A;  3TC9 A;  3O4P A;  1CRZ A;  2IAU A;  1CVM A;  2IVZ A;  4IYG A;  2POO A;  2IAR A;  4IMB A;  1RWI A;  2FP8 A;  1RWL A;  3S8V A;  2DG1 A;  1E1A A;  1IJQ A;  5GX4 A;  3AMR A;  4A0P A;  5D9D A;  5FWW A;  1NPE A;  2W8B B;  3AMS A;  2IAV A;  3SOQ A;  3P5B L;  3V65 B;  1POO A;  1H6L A;  4ZLR A;  4GNC A;  2IAX A;  3SOB B;  3G4E A;  4PWZ A;  3FW0 A;  3SOV A;  3FVZ A;  2DG0 A;  3WWA A;  4GNB A;  4HHQ A;  2GVV A;  3DR2 A;  3A9G A;  3HLH A;  4GN9 A;  3SRE A;  5GX5 A;  4HW6 A;  2GVX A;  1QLG A;  2IAT A;  2VAQ A;  3S2K A;  2FP9 A;  3A9H A;  3HRP A;  3E5Z A;  5GX1 A;  2GHS A;  2G8S A;  3Q6P A;  2IAQ A;  3S94 A;  3WW9 A;  1V04 A;  4JML A;  2FPC A;  3BYC A;  3DAS A;  3HLI A;  4O5S A;  1C5K A;  3IAX A;  2IAW A;  1N7D A;  2GVU A;  4HHO A;  3LI4 A;  3LI5 A;  1Q7F A;  2QE8 A;  5GTQ A;  2ISM A; 
#chains in the Genus database with same CATH topology
 1MS5 A;  3I1C A;  1ZGK A;  4XJU A;  3JU4 A;  1N1Y A;  1NNA A;  2QWF A;  2F12 A;  2P4O A;  4FPO B;  1E8V A;  2YA8 A;  4K1J A;  1IUC A;  3Q6T A;  4GZS A;  4CPO A;  5F9T A;  4GNA A;  3W09 A;  4CPY A;  4D52 C;  4MWU A;  2W5O A;  2AEQ A;  1IVD A;  1V3C A;  1C9U A;  1CRU A;  2GVW A;  2HQS A;  2RKC A;  2V91 A;  3KGG A;  1F8D A;  5FZJ A;  3SAN A;  2W8B A;  1INX A;  2XCY A;  1MWE A;  4BBW A;  4QN6 A;  1MS8 A;  2IAU A;  5FNS A;  1Z4V A;  1INH A;  3TI3 A;  1RWL A;  1DIM A;  4WEF A;  3H73 A;  1A4G A;  3K37 A;  3ALX A;  2SLI A;  3AMS A;  2IAV A;  1NN2 A;  1H6L A;  4YW4 A;  2ZWA A;  4ZLR A;  2QWC A;  2SIL A;  3G4E A;  1NMC A;  1W8O A;  4MWV A;  3SOV A;  4MZE A;  4XIL A;  4HHQ A;  2XZI A;  1N1T A;  4FPL A;  3SRE A;  2JKB A;  3A71 A;  4IFJ A;  4M4U A;  3K3A A;  4N1B A;  4MWL A;  4FPE A;  1QLG A;  1BJI A;  4YZ4 A;  1S1D A;  2HT7 A;  3A9H A;  3E5Z A;  2G8S A;  4FPG A;  3CL0 A;  1Z4Y A;  3WW9 A;  1Z50 A;  2XZK A;  3NN9 A;  4DGR A;  2FPC A;  1X2J A;  2QWJ A;  3BYC A;  1USR A;  2YA5 A;  3DAS A;  4YZ3 A;  4YY8 A;  4MWY A;  1MZ6 A;  4I00 A;  1EUR A;  4MC7 A;  3WN7 A;  4KS4 A;  1IVE A;  1MS0 A;  1N1V A;  4XJZ A;  3SLI A;  1C5K A;  1W8N A;  4IFL X;  4HIZ A;  4YW2 A;  2GVU A;  2HTQ A;  4IQK A;  3GVL A;  3LI4 A;  3LI5 A;  4YW1 A;  4K1H A;  2ISM A;  1N6F A;  4XE9 A;  3H72 A;  2WOZ A;  4L7C A;  4FOW A;  1MS9 A;  4XJA A;  4XYX A;  1U6D X;  4DG6 A;  2DSO A;  3ZGC A;  1QBI A;  2IAS A;  4XHX A;  1INV A;  4KS1 A;  1W0O A;  2C4A A;  1V0F A;  2BAT A;  3GVJ A;  4ASC A;  1NCA N;  5HUG A;  4YZ2 A;  1PJX A;  2FPB A;  4NC5 A;  2QWG A;  3SRG A;  5D9B A;  3K38 A;  4FP2 A;  4XMI A;  1SNT A;  4SLI A;  2BZD A;  5D9C A;  1Z4Z A;  1MR5 A;  4K1K A;  1NNC A;  2VW0 A;  4GN7 A;  3U0S A;  1B9S A;  4X47 A;  4GB1 A;  4H53 A;  1WCS A;  1CRZ A;  2VK6 A;  1E8U A;  1USX A;  4NCS A;  1WCQ A;  2FP8 A;  3S8V A;  1NMB N;  1E1A A;  4QN5 A;  5GX4 A;  4KS2 A;  1IVF A;  3AMR A;  4A0P A;  1B9V A;  4QN3 A;  1NSD A;  1NPE A;  4CSD A;  4AH4 A;  3SOQ A;  1MS1 A;  2W38 A;  4YZ1 A;  4GNC A;  4KS3 A;  1INY A;  4GDJ A;  2YA7 A;  2BF6 A;  4B7M A;  2F25 A;  4FPF A;  3FVZ A;  2FHR A;  1IUB A;  7NN9 A;  5F72 C;  1F8E A;  5B2D A;  2F11 A;  4GNB A;  4HZZ A;  4C1Y B;  2GVV A;  3HLH A;  2XZJ A;  5HUK A;  2F28 A;  4AHA A;  4GJT A;  1MZ5 A;  1WP5 A;  1L7F A;  2QWK A;  2F24 A;  4D52 A;  1NSB A;  4M4N A;  4AGT A;  2VW1 A;  2F29 A;  1A4Q A;  5EO8 A;  4UOU A;  3CKZ A;  1OFZ A;  4WA3 A;  4CHB A;  4GZP A;  1SLL A;  2FLU X;  3TI6 A;  4FP3 A;  1S0J A;  2AGS A;  4FPK A;  4MWJ A;  4FPC A;  3HLI A;  4AGI A;  2IAW A;  1N7D A;  1W1X A;  2SIM A;  3BEQ A;  3D11 A;  4K1I A;  2F10 A;  1MS4 A;  2H2U A;  4CPM A;  3B69 A;  1NSC A;  1EUS A;  2F13 A;  3G4H A;  3D12 A;  3S8Z A;  1N6E A;  3CYE A;  4XJ9 A;  3K36 A;  3TI5 A;  2ZZK A;  4D8S A;  1K32 A;  5JYY A;  1V3E A;  1NCC N;  2IAP A;  1V0E A;  4YZ5 A;  1CQ1 A;  1ING A;  5GX3 A;  3TI8 A;  2HTW A;  2Z32 A;  5EO7 A;  3Q6K A;  4CPL A;  2QWH A;  3V1S A;  4FPJ A;  2IAO A;  4IN4 A;  4Q1U A;  3II7 A;  2HTU A;  3NSS A;  2AH2 A;  2BER A;  1VCU A;  4GN8 A;  5GX2 A;  1XOG A;  3NO0 A;  4O5T A;  4WEG A;  4QN7 A;  3K39 A;  4YW3 A;  3SIL A;  3T1E A;  3TIC A;  1Z4W A;  1EUT A;  5M1Z A;  4WA5 A;  1INW A;  1CVM A;  2IVZ A;  4IYG A;  2POO A;  1V0Z A;  1RWI A;  4XJW A;  1VCJ A;  1L7G A;  2DG1 A;  4FZH A;  4MWW A;  1L7H A;  2VPJ A;  3ADE A;  2W8B B;  2W5N A;  2HU0 A;  2VSK A;  3UC1 A;  3P5B L;  1POO A;  3B7E A;  1IVG A;  3GVK A;  4FPY A;  1A14 N;  1IVB A;  1NMA N;  1W21 A;  5H47 A;  1SO7 A;  4PWZ A;  4MWQ A;  1IVC A;  1NCD N;  3H6J A;  3CL2 A;  2VSM A;  2DG0 A;  4UF7 A;  4FOQ A;  4B7R A;  4CPZ A;  3DR2 A;  3A9G A;  4MWR A;  4GN9 A;  4D52 B;  4M3M A;  2HT8 A;  5B2C A;  4HW6 A;  2GVX A;  5FNQ A;  4X4A A;  4XIK A;  1V2I A;  3S2K A;  2FP9 A;  4D4U A;  3HRP A;  2GHS A;  5FNU A;  5HUN A;  1N1S A;  2IAQ A;  4MZA A;  3S94 A;  1V04 A;  4XJR A;  2QWD A;  2QWE A;  1V3B A;  1S18 A;  4H52 A;  1V3D A;  4B7J A;  2VK5 A;  4IFN X;  4M4V A;  4O5S A;  2AEP A;  3IAX A;  4GZX A;  4ZY3 A;  3ALW A;  4ZGC A;  2YA4 A;  4B7Q A;  2QE8 A;  2YDT A;  2ZB5 A;  4G3N A;  4X6K A;  4HZY A;  4MWX A;  1NNB A;  3A72 A;  1B9T A;  4FPH A;  2YA6 A;  4KS5 A;  3INB A;  2HTR A;  4J9T A;  4YW5 A;  4FOV A;  2HU4 A;  2W20 A;  3O9J A;  4R40 A;  4XJQ A;  1SUU A;  4QNP A;  4JF7 A;  1SLI A;  4GEZ A;  4XIO A;  3L6V A;  4GDI A;  3WDZ A;  4HZV A;  4HZX A;  3KYA A;  2QWA A;  3ZGD A;  1DIL A;  1ZI0 A;  2CML A;  3VNH A;  4B7N A;  1INF A;  5FNR A;  5HUM A;  5FZN A;  2ZB6 A;  3LI3 A;  4XMA A;  5EX7 A;  2HT5 A;  2A75 A;  1N6D A;  3OPZ A;  3V64 C;  1W20 A;  2XN4 A;  2DYH A;  1X2R A;  2OJH A;  4QN4 A;  3TC9 A;  3O4P A;  4K3Y A;  4FOY A;  2IAR A;  5CGJ A;  4IMB A;  4NN9 A;  1W0P A;  3SAL A;  2F27 A;  2B8H A;  1IJQ A;  1E8T A;  3VNG A;  5D9D A;  3PJQ A;  4C1Y A;  4L7D A;  2H2N A;  5FWW A;  4MJV A;  4FQ4 A;  4Q6K A;  4X49 A;  3V65 B;  4XMB A;  3TIB A;  2C4L A;  4MJU A;  2QWI A;  4FJ6 A;  3H71 A;  4WA4 A;  5FNT A;  2IAX A;  4GZO A;  3SOB B;  3FW0 A;  1KIT A;  4XHB A;  1F8C A;  4L7B A;  3WWA A;  4MX0 A;  4GZQ A;  5GX5 A;  2VWD A;  1S0I A;  4GZT A;  2VK7 A;  1NCB N;  2VVZ A;  6NN9 A;  4GZW A;  2YDP A;  2HTY A;  1F8B A;  2F0Z A;  2IAT A;  1EUU A;  2VAQ A;  5GX1 A;  3Q6P A;  1MS3 A;  1XOE A;  2F26 A;  4XJ8 A;  2X9M A;  4JML A;  3TIA A;  4FVK A;  4HZW A;  5NN9 A;  4XOG A;  2QWB A;  3O9K A;  3TI4 A;  2VW2 A;  4CH9 A;  2ZW9 A;  2HTV A;  1Z4X A;  4HHO A;  1Q7F A;  5HX0 A;  4CPN A;  5GTQ A; 
#chains in the Genus database with same CATH homology
 3I1C A;  3G4H A;  3S8Z A;  4DG6 A;  2DSO A;  1QBI A;  2IAS A;  4R40 A;  2P4O A;  3Q6T A;  4GNA A;  2IAP A;  1PJX A;  2FPB A;  1CQ1 A;  3SRG A;  3KYA A;  5GX3 A;  5D9B A;  3Q6K A;  3V1S A;  5D9C A;  2IAO A;  1C9U A;  4Q1U A;  1CRU A;  2GVW A;  3LI3 A;  2V91 A;  2HQS A;  5EX7 A;  4GN8 A;  5GX2 A;  3KGG A;  4GN7 A;  4O5T A;  3U0S A;  2W8B A;  3V64 C;  2OJH A;  3TC9 A;  3O4P A;  1CRZ A;  2IAU A;  1CVM A;  2IVZ A;  4IYG A;  2POO A;  2IAR A;  4IMB A;  1RWI A;  2FP8 A;  1RWL A;  3S8V A;  2DG1 A;  1E1A A;  1IJQ A;  5GX4 A;  3AMR A;  4A0P A;  5D9D A;  5FWW A;  1NPE A;  2W8B B;  3AMS A;  2IAV A;  3SOQ A;  3P5B L;  3V65 B;  1POO A;  1H6L A;  4ZLR A;  4GNC A;  2IAX A;  3SOB B;  3G4E A;  4PWZ A;  3FW0 A;  3SOV A;  3FVZ A;  2DG0 A;  3WWA A;  4GNB A;  4HHQ A;  2GVV A;  3DR2 A;  3A9G A;  3HLH A;  4GN9 A;  3SRE A;  5GX5 A;  4HW6 A;  2GVX A;  1QLG A;  2IAT A;  2VAQ A;  3S2K A;  2FP9 A;  3A9H A;  3HRP A;  3E5Z A;  5GX1 A;  2GHS A;  2G8S A;  3Q6P A;  2IAQ A;  3S94 A;  3WW9 A;  1V04 A;  4JML A;  2FPC A;  3BYC A;  3DAS A;  3HLI A;  4O5S A;  1C5K A;  3IAX A;  2IAW A;  1N7D A;  2GVU A;  4HHO A;  3LI4 A;  3LI5 A;  1Q7F A;  2QE8 A;  5GTQ A;  2ISM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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