3SIHA

The x-ray crystal structure of poly(adp-ribose) glycohydrolase (parg) from thermomonospora curvata
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
274
structure length
274
Chain Sequence
RHSRRAIAAETVEILERGRYTAPSGRVVPIADHVAQAVRGTRLYRPEKLAVLLEGLGAASDGAPTRIEVTEETTLAAARRLTGAAGDQVACLNFASAEHPGGGFLSGAHAQEEGLARSSGLYASLRAVPQFYAFHHRQRDPLYSDHLIYSPGVPVFRDDAGRLLEEPYRVAFLTSPAPNRRAIGDLRTVEEIGRVLRGRAAKVLAAARHHGHRRLVLGAWGCGVFGNDPAQVAETFAGLLLDGGPFAGRFAHVVFAVWDTAPGAPRHAAFARRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords poly(ADP-ribose) glycohydrolase
publication title The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
pubmed doi rcsb
source organism Thermomonospora curvata
molecule tags Hydrolase
total genus 94
structure length 274
sequence length 274
ec nomenclature ec 3.2.1.143: Poly(ADP-ribose) glycohydrolase.
pdb deposition date 2011-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10021 DUF2263 Uncharacterized protein conserved in bacteria (DUF2263)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3sihA00
3EJFA 4ETKA 3KQZA 3KR5A 3Q6ZA 4X2TA 3EWOA 4ABKA 4R7MA 2FG1A 1NJRA 3EWRA 3Q71A 4GVWA 4ZX8A 4ZI6A 4GVVA 4J5SA 2ACFA 1BLLE 1LAMA 1LCPA 4D86A 1GYTA 4ABLA 3IIFA 1LANA 4KYBA 2BFRA 3V45A 5DUSA 5FSUA 3PEIA 5CMSA 3SIGA 4ZY0A 2LGRA 3GPGA 5FSVA 4ZX9A 3EWPA 2BFQA 3EWQA 5D8NA 3SIHA 2AFCA 2XD7A 3EJGA 3JZTA 3H8GA 4R76A 5E3BA 3JRUA 3H8EA 4JLLA 3GPOA 4J4ZA 4K3NA 1YD9A 5HOLA 2FXKA 3GQEA 4ZYQA 5FSXA 2FAVA 1LAPA 4J5QA 3SIIA 3V2BA 3IJ3A 3IIDA 4TU0A 5HIHA 3KQXA 5CB5A 1SPVA 2L8RA 4ZY2A 3VFQA 4JCAA 4GUAA 3GPQA 5CBMA 3EKEA 3T8WA 5AILA 2EWBA 2DX6A 3H8FA 2J9AA 1BPMA 4IQYA 1HJZA 1ZR5A 4ZY1A 3KR4A 3ETIA 4ETJA 3KZWA 5FSZA 5CB3A 3SIJA 4R6TA 3GQOA 1TY8A 2X47A 3EW5A 4J5RA 1VHUA 2VRIA 4ESSA 4JGKA 1TXZA 4UMLA 4K0CA 5FSYA 4KSIA 1ZR3A 4JVVA 1BPNA 2EEEA
chains in the Genus database with same CATH superfamily
3EJFA 4ETKA 3KQZA 3KR5A 3Q6ZA 4X2TA 3EWOA 4ABKA 4R7MA 2FG1A 1NJRA 2RNKA 3EWRA 3Q71A 4GVWA 4ZX8A 4ZI6A 4GVVA 4J5SA 2ACFA 1BLLE 1LAMA 1LCPA 4D86A 1GYTA 4ABLA 3IIFA 1LANA 4KYBA 2BFRA 3V45A 5DUSA 5FSUA 2JZFA 3PEIA 5CMSA 3SIGA 4ZY0A 2LGRA 3GPGA 5FSVA 4ZX9A 3EWPA 2BFQA 3EWQA 5D8NA 3SIHA 2AFCA 2XD7A 3EJGA 3JZTA 3H8GA 4R76A 5E3BA 3JRUA 3H8EA 4JLLA 3GPOA 4J4ZA 4K3NA 1YD9A 5HOLA 2FXKA 3GQEA 4ZYQA 5FSXA 2FAVA 1LAPA 4J5QA 3SIIA 3V2BA 3IJ3A 3IIDA 4TU0A 5HIHA 3KQXA 5CB5A 1SPVA 2L8RA 4ZY2A 3VFQA 4JCAA 4GUAA 3GPQA 5CBMA 3EKEA 3T8WA 5AILA 2WCTA 2EWBA 2W2GA 2DX6A 3H8FA 2J9AA 1BPMA 4IQYA 1HJZA 1ZR5A 4ZY1A 3KR4A 3ETIA 4ETJA 2JZEA 3KZWA 5FSZA 5CB3A 3SIJA 4R6TA 3GQOA 1TY8A 2X47A 3EW5A 4J5RA 1VHUA 2VRIA 4ESSA 4JGKA 1TXZA 2KQVA 4UMLA 4K0CA 2JZDA 4KSIA 5FSYA 1ZR3A 4JVVA 1BPNA 2EEEA
chains in the Genus database with same CATH topology
3EJFA 4ETKA 3KQZA 3KR5A 3Q6ZA 4X2TA 3EWOA 4ABKA 4R7MA 2FG1A 1NJRA 3EWRA 3Q71A 4GVWA 4ZX8A 4ZI6A 4GVVA 4J5SA 2ACFA 1BLLE 1LAMA 1LCPA 4D86A 1GYTA 4ABLA 3IIFA 1LANA 4KYBA 2BFRA 3V45A 5DUSA 5FSUA 3PEIA 5CMSA 3SIGA 4ZY0A 2LGRA 3GPGA 5FSVA 4ZX9A 3EWPA 2BFQA 3EWQA 5D8NA 3SIHA 2AFCA 2XD7A 3EJGA 3JZTA 3H8GA 4R76A 5E3BA 3JRUA 3H8EA 4JLLA 3GPOA 4J4ZA 4K3NA 1YD9A 5HOLA 2FXKA 3GQEA 4ZYQA 5FSXA 2FAVA 1LAPA 4J5QA 3SIIA 3V2BA 3IJ3A 3IIDA 4TU0A 5HIHA 3KQXA 5CB5A 1SPVA 2L8RA 4ZY2A 3VFQA 4JCAA 4GUAA 3GPQA 5CBMA 3EKEA 3T8WA 5AILA 2EWBA 2DX6A 3H8FA 2J9AA 1BPMA 4IQYA 1HJZA 1ZR5A 4ZY1A 3KR4A 3ETIA 4ETJA 3KZWA 5FSZA 5CB3A 3SIJA 4R6TA 3GQOA 1TY8A 2X47A 3EW5A 4J5RA 1VHUA 2VRIA 4ESSA 4JGKA 1TXZA 4UMLA 4K0CA 5FSYA 4KSIA 1ZR3A 4JVVA 1BPNA 2EEEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EJF A;  4ETK A;  3KQZ A;  3KR5 A;  3Q6Z A;  4X2T A;  3EWO A;  4ABK A;  4R7M A;  2FG1 A;  1NJR A;  3EWR A;  3Q71 A;  4GVW A;  4ZX8 A;  4ZI6 A;  4GVV A;  4J5S A;  2ACF A;  1BLL E;  1LAM A;  1LCP A;  4D86 A;  1GYT A;  4ABL A;  3IIF A;  1LAN A;  4KYB A;  2BFR A;  3V45 A;  5DUS A;  5FSU A;  3PEI A;  5CMS A;  3SIG A;  4ZY0 A;  2LGR A;  3GPG A;  5FSV A;  4ZX9 A;  3EWP A;  2BFQ A;  3EWQ A;  5D8N A;  3SIH A;  2AFC A;  2XD7 A;  3EJG A;  3JZT A;  3H8G A;  4R76 A;  5E3B A;  3JRU A;  3H8E A;  4JLL A;  3GPO A;  4J4Z A;  4K3N A;  1YD9 A;  5HOL A;  2FXK A;  3GQE A;  4ZYQ A;  5FSX A;  2FAV A;  1LAP A;  4J5Q A;  3SII A;  3V2B A;  3IJ3 A;  3IID A;  4TU0 A;  5HIH A;  3KQX A;  5CB5 A;  1SPV A;  2L8R A;  4ZY2 A;  3VFQ A;  4JCA A;  4GUA A;  3GPQ A;  5CBM A;  3EKE A;  3T8W A;  5AIL A;  2EWB A;  2DX6 A;  3H8F A;  2J9A A;  1BPM A;  4IQY A;  1HJZ A;  1ZR5 A;  4ZY1 A;  3KR4 A;  3ETI A;  4ETJ A;  3KZW A;  5FSZ A;  5CB3 A;  3SIJ A;  4R6T A;  3GQO A;  1TY8 A;  2X47 A;  3EW5 A;  4J5R A;  1VHU A;  2VRI A;  4ESS A;  4JGK A;  1TXZ A;  4UML A;  4K0C A;  5FSY A;  4KSI A;  1ZR3 A;  4JVV A;  1BPN A;  2EEE A; 
#chains in the Genus database with same CATH topology
 3EJF A;  4ETK A;  3KQZ A;  3KR5 A;  3Q6Z A;  4X2T A;  3EWO A;  4ABK A;  4R7M A;  2FG1 A;  1NJR A;  2RNK A;  3EWR A;  3Q71 A;  4GVW A;  4ZX8 A;  4ZI6 A;  4GVV A;  4J5S A;  2ACF A;  1BLL E;  1LAM A;  1LCP A;  4D86 A;  1GYT A;  4ABL A;  3IIF A;  1LAN A;  4KYB A;  2BFR A;  3V45 A;  5DUS A;  5FSU A;  2JZF A;  3PEI A;  5CMS A;  3SIG A;  4ZY0 A;  2LGR A;  3GPG A;  5FSV A;  4ZX9 A;  3EWP A;  2BFQ A;  3EWQ A;  5D8N A;  3SIH A;  2AFC A;  2XD7 A;  3EJG A;  3JZT A;  3H8G A;  4R76 A;  5E3B A;  3JRU A;  3H8E A;  4JLL A;  3GPO A;  4J4Z A;  4K3N A;  1YD9 A;  5HOL A;  2FXK A;  3GQE A;  4ZYQ A;  5FSX A;  2FAV A;  1LAP A;  4J5Q A;  3SII A;  3V2B A;  3IJ3 A;  3IID A;  4TU0 A;  5HIH A;  3KQX A;  5CB5 A;  1SPV A;  2L8R A;  4ZY2 A;  3VFQ A;  4JCA A;  4GUA A;  3GPQ A;  5CBM A;  3EKE A;  3T8W A;  5AIL A;  2WCT A;  2EWB A;  2W2G A;  2DX6 A;  3H8F A;  2J9A A;  1BPM A;  4IQY A;  1HJZ A;  1ZR5 A;  4ZY1 A;  3KR4 A;  3ETI A;  4ETJ A;  2JZE A;  3KZW A;  5FSZ A;  5CB3 A;  3SIJ A;  4R6T A;  3GQO A;  1TY8 A;  2X47 A;  3EW5 A;  4J5R A;  1VHU A;  2VRI A;  4ESS A;  4JGK A;  1TXZ A;  2KQV A;  4UML A;  4K0C A;  2JZD A;  4KSI A;  5FSY A;  1ZR3 A;  4JVV A;  1BPN A;  2EEE A; 
#chains in the Genus database with same CATH homology
 3EJF A;  4ETK A;  3KQZ A;  3KR5 A;  3Q6Z A;  4X2T A;  3EWO A;  4ABK A;  4R7M A;  2FG1 A;  1NJR A;  3EWR A;  3Q71 A;  4GVW A;  4ZX8 A;  4ZI6 A;  4GVV A;  4J5S A;  2ACF A;  1BLL E;  1LAM A;  1LCP A;  4D86 A;  1GYT A;  4ABL A;  3IIF A;  1LAN A;  4KYB A;  2BFR A;  3V45 A;  5DUS A;  5FSU A;  3PEI A;  5CMS A;  3SIG A;  4ZY0 A;  2LGR A;  3GPG A;  5FSV A;  4ZX9 A;  3EWP A;  2BFQ A;  3EWQ A;  5D8N A;  3SIH A;  2AFC A;  2XD7 A;  3EJG A;  3JZT A;  3H8G A;  4R76 A;  5E3B A;  3JRU A;  3H8E A;  4JLL A;  3GPO A;  4J4Z A;  4K3N A;  1YD9 A;  5HOL A;  2FXK A;  3GQE A;  4ZYQ A;  5FSX A;  2FAV A;  1LAP A;  4J5Q A;  3SII A;  3V2B A;  3IJ3 A;  3IID A;  4TU0 A;  5HIH A;  3KQX A;  5CB5 A;  1SPV A;  2L8R A;  4ZY2 A;  3VFQ A;  4JCA A;  4GUA A;  3GPQ A;  5CBM A;  3EKE A;  3T8W A;  5AIL A;  2EWB A;  2DX6 A;  3H8F A;  2J9A A;  1BPM A;  4IQY A;  1HJZ A;  1ZR5 A;  4ZY1 A;  3KR4 A;  3ETI A;  4ETJ A;  3KZW A;  5FSZ A;  5CB3 A;  3SIJ A;  4R6T A;  3GQO A;  1TY8 A;  2X47 A;  3EW5 A;  4J5R A;  1VHU A;  2VRI A;  4ESS A;  4JGK A;  1TXZ A;  4UML A;  4K0C A;  5FSY A;  4KSI A;  1ZR3 A;  4JVV A;  1BPN A;  2EEE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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