3SLPA

Crystal structure of lambda exonuclease in complex with a 12 bp symmetric dna duplex
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
226
structure length
226
Chain Sequence
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFDEIVPEFIEKMDEALAEIGFVFGEQWR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Enterobacteria phage lambda
molecule keywords Exonuclease
total genus 75
structure length 226
sequence length 226
chains with identical sequence B, C
ec nomenclature ec 3.1.11.3: Exodeoxyribonuclease (lambda-induced).
pdb deposition date 2011-06-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09588 YqaJ YqaJ-like viral recombinase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 3slpA00
4IC1A 3SM4A 4CEJA 3H4RA 4CEHA 3L0AA 3K70B 3SZ5A 3U4QA 3SYYA 3K93A 3SZ4A 5LD2B 4WUZA 3SLPA 1AVQA 3U44A 1W36B 4R5QA 4CEIA
chains in the Genus database with same CATH superfamily
1HBUC 3M2VC 5A8RC 1HBNC 4IC1A 3M2RC 3SM4A 4CEJA 3H4RA 5A8KC 4R5QA 1E6VC 1HBOC 3M30C 4CEHA 3L0AA 3M1VC 3K70B 5A0YC 3SZ5A 1HBMC 3U4QA 3M2UC 5A8WC 3SYYA 3K93A 3SZ4A 5LD2B 3M32C 4WUZA 3SLPA 1AVQA 3U44A 1W36B 3SQGC 5G0RC 1MROC 3POTC 1E6YC 4CEIA
chains in the Genus database with same CATH topology
4IC1A 3SM4A 4CEJA 3H4RA 4CEHA 3L0AA 3K70B 3SZ5A 3U4QA 3SYYA 3K93A 3SZ4A 5LD2B 4WUZA 3SLPA 1AVQA 3U44A 1W36B 4R5QA 4CEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IC1 A;  3SM4 A;  4CEJ A;  3H4R A;  4CEH A;  3L0A A;  3K70 B;  3SZ5 A;  3U4Q A;  3SYY A;  3K93 A;  3SZ4 A;  5LD2 B;  4WUZ A;  3SLP A;  1AVQ A;  3U44 A;  1W36 B;  4R5Q A;  4CEI A; 
#chains in the Genus database with same CATH topology
 1HBU C;  3M2V C;  5A8R C;  1HBN C;  4IC1 A;  3M2R C;  3SM4 A;  4CEJ A;  3H4R A;  5A8K C;  4R5Q A;  1E6V C;  1HBO C;  3M30 C;  4CEH A;  3L0A A;  3M1V C;  3K70 B;  5A0Y C;  3SZ5 A;  1HBM C;  3U4Q A;  3M2U C;  5A8W C;  3SYY A;  3K93 A;  3SZ4 A;  5LD2 B;  3M32 C;  4WUZ A;  3SLP A;  1AVQ A;  3U44 A;  1W36 B;  3SQG C;  5G0R C;  1MRO C;  3POT C;  1E6Y C;  4CEI A; 
#chains in the Genus database with same CATH homology
 4IC1 A;  3SM4 A;  4CEJ A;  3H4R A;  4CEH A;  3L0A A;  3K70 B;  3SZ5 A;  3U4Q A;  3SYY A;  3K93 A;  3SZ4 A;  5LD2 B;  4WUZ A;  3SLP A;  1AVQ A;  3U44 A;  1W36 B;  4R5Q A;  4CEI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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