3SLPA

Crystal structure of lambda exonuclease in complex with a 12 bp symmetric dna duplex
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
226
structure length
226
Chain Sequence
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFDEIVPEFIEKMDEALAEIGFVFGEQWR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/dna
molecule keywords Exonuclease
publication title Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
pubmed doi rcsb
source organism Enterobacteria phage lambda
total genus 75
structure length 226
sequence length 226
chains with identical sequence B, C
ec nomenclature ec 3.1.11.3: Exodeoxyribonuclease (lambda-induced).
pdb deposition date 2011-06-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09588 YqaJ YqaJ-like viral recombinase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 3slpA00
3L0AA 3U44A 3K93A 3H4RA 3U4QA 4R5QA 4CEHA 4CEJA 3K70B 3SZ5A 1W36B 3SLPA 1AVQA 4WUZA 5LD2B 4CEIA 4IC1A 3SZ4A 3SYYA 3SM4A
chains in the Genus database with same CATH superfamily
1HBOC 1MROC 5A8RC 1HBUC 3L0AA 3M30C 3M2RC 3U44A 3K93A 3H4RA 1E6YC 3U4QA 4R5QA 5A8KC 4CEHA 1HBMC 4CEJA 3M1VC 5A0YC 3SZ5A 3K70B 3M2UC 1W36B 3SM4A 3SLPA 1AVQA 1HBNC 4WUZA 5LD2B 4CEIA 3M32C 5G0RC 3SQGC 1E6VC 4IC1A 5A8WC 3M2VC 3SZ4A 3SYYA 3POTC
chains in the Genus database with same CATH topology
3L0AA 3U44A 3K93A 3H4RA 3U4QA 4R5QA 4CEHA 4CEJA 3K70B 3SZ5A 1W36B 3SLPA 1AVQA 4WUZA 5LD2B 4CEIA 4IC1A 3SZ4A 3SYYA 3SM4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L0A A;  3U44 A;  3K93 A;  3H4R A;  3U4Q A;  4R5Q A;  4CEH A;  4CEJ A;  3K70 B;  3SZ5 A;  1W36 B;  3SLP A;  1AVQ A;  4WUZ A;  5LD2 B;  4CEI A;  4IC1 A;  3SZ4 A;  3SYY A;  3SM4 A; 
#chains in the Genus database with same CATH topology
 1HBO C;  1MRO C;  5A8R C;  1HBU C;  3L0A A;  3M30 C;  3M2R C;  3U44 A;  3K93 A;  3H4R A;  1E6Y C;  3U4Q A;  4R5Q A;  5A8K C;  4CEH A;  1HBM C;  4CEJ A;  3M1V C;  5A0Y C;  3SZ5 A;  3K70 B;  3M2U C;  1W36 B;  3SM4 A;  3SLP A;  1AVQ A;  1HBN C;  4WUZ A;  5LD2 B;  4CEI A;  3M32 C;  5G0R C;  3SQG C;  1E6V C;  4IC1 A;  5A8W C;  3M2V C;  3SZ4 A;  3SYY A;  3POT C; 
#chains in the Genus database with same CATH homology
 3L0A A;  3U44 A;  3K93 A;  3H4R A;  3U4Q A;  4R5Q A;  4CEH A;  4CEJ A;  3K70 B;  3SZ5 A;  1W36 B;  3SLP A;  1AVQ A;  4WUZ A;  5LD2 B;  4CEI A;  4IC1 A;  3SZ4 A;  3SYY A;  3SM4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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