3SMEA

Structure of ptp1b inactivated by h2o2/bicarbonate
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
282
structure length
282
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Biological Buffer Bicarbonate/CO(2) Potentiates H(2)O(2)-Mediated Inactivation of Protein Tyrosine Phosphatases.
pubmed doi rcsb
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
molecule tags Hydrolase
source organism Homo sapiens
total genus 98
structure length 282
sequence length 282
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2011-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3smeA00
4WOHA 1YGUA 4OHDA 2CNGA 3EZZA 4MBBA 3V0JA 2F6TA 5LXQB 3O5XA 1P15A 2H03A 2AHSA 1GWZA 3V0DA 3SR9A 2A3KA 2OC3A 2VEVA 2CNFA 1Q1MA 1OEUA 2A8BA 2BIJA 4QAHA 2VEXA 2I42A 2F6ZA 2F6WA 1C85A 4QBEA 5EHRA 1M3GA 2B4PA 2FJMA 1G4US 3O4TA 1XXVA 1XRIA 2CNIA 2GJTA 1YTWA 5AWXA 1V3AA 1BZCA 1Q6NA 2H4GA 2CMCA 1ZZWA 2I4EA 3QCGA 1X24A 3MOWA 1PTYA 3AWGA 2OUDA 4RI5A 4JMJA 2NTAA 1OESA 2GWOA 1ONYA 2BV5A 1YN9A 4NYHA 4BJOA 1Q6PA 1WCHA 3D44A 1PXHA 1PYNA 2QBQA 2G59A 1VHRA 3QCFA 4WU2A 3ZM3A 5BZZA 2ESBA 1PA1A 4BPCA 1OHDA 5M43A 1G7GA 5EHPA 2Q47A 3ZM1A 1PH0A 3BRHA 4JBCA 2QDCA 4WU3A 1FPZA 2IMGA 5K23A 1ECVA 1L8GA 1I57A 5GTJA 2P4DA 2NLKA 2E0TA 1XM2A 4RDDA 1PA9A 4OHLA 2I6MA 4OHHA 1C86A 3RGOA 2I1YA 2HNPA 3EU0A 2I6IA 3S3HA 4Y14A 1G7FA 5BUGA 2HB1A 1KAKA 2QBPA 2F6FA 2OZ5A 5KA8A 2PI7A 2SHPA 4RH9A 5KA2A 3GXHA 4PYHA 5I6VA 3OMHA 3NMEA 1XXPA 3ZM2A 3F81A 5KA4A 2QBRA 4D3QA 2B4UA 5BX1A 3ZMPA 3V0GA 1ZCLA 1NNYA 5KA3A 3QCLA 3I80A 4OHIA 2NT2A 4GE2A 1C84A 1I9SA 3QCJA 4RH5A 2I5XA 2I3UA 2F46A 2QDPA 2H4KA 4ZN5A 4YAAA 4GRYA 1RXDA 2I4HA 2GP0A 3V0FA 4GE5A 4KI9A 2B07A 1YPTA 4GFVA 4RKKA 5K24A 1PTUA 4GRZA 5BZXA 3S4EA 1G1HA 3O4UA 1D5RA 2M3VA 3LJ8A 1RPMA 3V0IA 4Z6BA 3A5KA 1Q6TA 3GXGA 3EMUA 4D3PA 1YTNA 3EAXA 5K22A 5KABA 4NWGA 2CM7A 2I6OA 4GS0A 1NL9A 3O4SA 3RO1A 3D1HA 5KADA 4RI4A 1EEOA 2FJNA 3MOZA 1Q6JA 5K9WA 3D9CA 1ONZA 2PBNA 2H02A 3V0HA 3QCBA 1T4JA 1FQ1A 3ZM0A 1LARA 1LYVA 1I9TA 4QAPA 5IBSA 2H04A 4RHGA 2PT0A 3AWEA 1OHEA 2BGDA 3F9AA 4GE6A 4D3RA 2QCTA 1WAXA 1U25A 3I36A 3ZV2A 1U24A 2CMAA 2NZ6A 5J8RA 2F70A 5KA1A 4GFUA 1PTVA 3H2XA 3MMJA 1QXKA 2PQ5A 3S3KA 4WTYA 3QCIA 2NV5A 1NWEA 4PVGA 2Y2FA 2CM8A 4IKCA 2QCJA 2F6VA 4DGPA 2I75A 2J16B 1KAVA 1C87A 4JNBA 4QBWA 2OOQA 1BZJA 1R6HA 2CJZA 2I6PA 2HXPA 2VEWA 2I3RA 4ZI4A 3F99A 3CWEA 1EENA 2NT7A 5IBMA 4OHEA 3O3LA 1QZ0A 1Q6MA 3QCHA 4I8NA 2CMBA 2B49A 1YWFA 4Y2EA 2JJDA 3RZ2A 3U96A 1T48A 2PA5A 1J4XA 2VEYA 3D1QA 2C46A 1YTSA 4H1OA 3QKQA 1BZHA 4AZ1A 5K9VA 4KYQA 1OHCA 2G6ZA 4S0GA 2HC1A 3QKPA 3QCCA 4KYRA 3ZMQA 1YZ4A 2I4GA 3AWFA 2B3OA 2AZRA 2HNQA 3D42A 3QCDA 2CNEA 5KA7A 2YDUA 5HDEA 4H34A 2MBCA 4NNDA 2CNHA 1PTTA 1XBOA 2CM3A 5KA9A 4QUNA 3BLUA 2PSZA 2QEPA 2H4VA 4ERCA 3M4UA 1LQFA 1YGRA 4HJQA 4TVVA 2F6YA 2B4OA 3BM8A 2ZN7A 4HRFA 4NWFA 2HVLA 1Q6SA 5KA0A 3QCMA 1C83A 2HC2A 2R0BA 2J16A 2CM2A 2P6XA 1U26A 4YR8B 1A5YA 3S4OA 2VEUA 1NWLA 1NZ7A 2WGPA 4R0TA 2CFVA 1L8KA 1JF7A 2DXPA 2I6JA 3QCNA 4B04A 4QUMA 2Q05A 1JLNA 2QBSA 5MMZB 2HCMA 3V0EA 1OEVA 1ZC0A 1AAXA 1SUGA 3F9BA 3EB1A 2RF6A 2F71A 4R30A 1G4WR 1ZCKA 1YFOA 2BGEA 3A5JA 2QDMA 1G1GA 3BLTA 2B4SA 3S3EA 4JMKA 3QCKA 5KACA 4ICZA 4ZRTA 1OETA 4NX8A 1OEOX 2HY3A 3QCEA 4R0SA 1FPRA 3I7ZA 1NO6A 3F41A 3OLRA 1T49A 5KAAA 1WRMA 4J51A 1GFYA 1G1FA 3B7OA 3RGQA 1OEMX 1MKPA 3CM3A 3N0AA 4DGXA 2ZMMA 4GWFA 5K25A 2J17A 3D1OA 3PS5A 2FH7A 3S3FA 1C88A 4HJPA 2C7SA 3SMEA 2Y96A 2BZLA
chains in the Genus database with same CATH superfamily
4WOHA 1YGUA 4OHDA 2CNGA 3EZZA 1EEHA 4MBBA 3V0JA 2F6TA 5LXQB 3O5XA 1P15A 2H03A 2AHSA 1GWZA 3V0DA 3SR9A 2A3KA 2OC3A 1E8CA 1P3DA 2VEVA 2CNFA 1Q1MA 1OEUA 2A8BA 2BIJA 4QAHA 2VEXA 2I42A 2F6ZA 2F6WA 1C85A 4QBEA 5EHRA 1M3GA 2B4PA 2FJMA 4UAGA 1G4US 3O4TA 4CVKA 2Y66A 1XXVA 1XRIA 2CNIA 2GJTA 1YTWA 5AWXA 1V3AA 1BZCA 1Q6NA 4BUBA 2H4GA 1JBVA 2CMCA 1ZZWA 2I4EA 3QCGA 2UAGA 1X24A 3MOWA 2XPCA 4C13A 1PTYA 1JBWA 1FGSA 3AWGA 3PYZA 4QF5A 2OUDA 4RI5A 4JMJA 2NTAA 1OESA 2GWOA 1ONYA 3ZL8A 2BV5A 2AM1A 1YN9A 4NYHA 4BJOA 1Q6PA 1WCHA 3LK7A 3D44A 1PXHA 1PYNA 2QBQA 2G59A 2VOSA 1VHRA 3QCFA 4WU2A 3ZM3A 5BZZA 2ESBA 1PA1A 4BPCA 1OHDA 5M43A 1G7GA 5EHPA 2Q47A 2Y1OA 3ZM1A 1PH0A 3BRHA 4JBCA 2QDCA 4WU3A 1FPZA 2IMGA 2XJAA 5K23A 1ECVA 1L8GA 1I57A 5GTJA 2P4DA 2NLKA 2E0TA 1XM2A 4RDDA 1PA9A 4OHLA 2I6MA 1GQQA 2GC5A 4OHHA 1C86A 3RGOA 2I1YA 2HNPA 3EU0A 5A5EA 2I6IA 3S3HA 4CVLA 4Y14A 1G7FA 5BUGA 2HB1A 1KAKA 2QBPA 2F6FA 2OZ5A 5KA8A 2PI7A 2SHPA 4RH9A 4ZIYA 5KA2A 3GXHA 4PYHA 5I6VA 3OMHA 3NMEA 1XXPA 3ZM2A 3F81A 5KA4A 2QBRA 4D3QA 2B4UA 5BX1A 3ZMPA 3V0GA 1ZCLA 2VORA 1NNYA 5KA3A 3QCLA 3I80A 4OHIA 2NT2A 3ZM5A 4GE2A 1C84A 1I9SA 3QCJA 4RH5A 2I5XA 2I3UA 2F46A 2JFHA 2QDPA 2H4KA 4ZN5A 4YAAA 4GRYA 1RXDA 2I4HA 2GP0A 1J6UA 3V0FA 4GE5A 4KI9A 2B07A 1YPTA 4GFVA 4RKKA 5K24A 1PTUA 4GRZA 5BZXA 3S4EA 1G1HA 3O4UA 1D5RA 2M3VA 3LJ8A 1RPMA 3V0IA 4Z6BA 1UAGA 3A5KA 1Q6TA 3GXGA 3EMUA 2WJPA 1YTNA 4D3PA 3EAXA 5K22A 5KABA 4NWGA 2CM7A 2I6OA 4GS0A 1NL9A 3O4SA 3RO1A 3D1HA 3N2AA 5KADA 4RI4A 1EEOA 2FJNA 3MOZA 1Q6JA 5K9WA 3D9CA 1ONZA 2PBNA 2H02A 3V0HA 3QCBA 1T4JA 1FQ1A 3ZM0A 1LARA 1LYVA 1I9TA 2JFGA 4QAPA 5IBSA 2H04A 4RHGA 2PT0A 3AWEA 1OHEA 2BGDA 3F9AA 4GE6A 4D3RA 2X5OA 1GG4A 2VTEA 2QCTA 1WAXA 1U25A 3I36A 1O5ZA 3ZV2A 1U24A 2CMAA 2NZ6A 5J8RA 2F70A 5KA1A 4GFUA 1PTVA 3H2XA 3MMJA 1QXKA 2PQ5A 1W78A 4BUCA 3S3KA 4WTYA 3QCIA 2NV5A 1NWEA 4PVGA 2Y2FA 2CM8A 4IKCA 2QCJA 2F6VA 4DGPA 2I75A 2J16B 1KAVA 1C87A 4JNBA 4QBWA 1GQYA 2OOQA 1BZJA 1R6HA 2CJZA 2I6PA 2HXPA 2VEWA 2I3RA 4ZI4A 3F99A 3CWEA 1EENA 2NT7A 5IBMA 4OHEA 3O3LA 1QZ0A 2Y67A 4HV4A 1Q6MA 3QCHA 1E0DA 4I8NA 2CMBA 1W7KA 2B49A 1YWFA 4Y2EA 2JJDA 3RZ2A 3U96A 1T48A 2PA5A 1P31A 1J4XA 2VEYA 3D1QA 2C46A 1YTSA 4H1OA 3QKQA 1BZHA 4CVMA 4AZ1A 5K9VA 4KYQA 1OHCA 4QDIA 2GCBA 2G6ZA 4S0GA 2HC1A 3QKPA 3QCCA 4KYRA 3ZMQA 1YZ4A 2I4GA 3AWFA 2B3OA 2AZRA 2F00A 2HNQA 3D42A 3QCDA 2CNEA 5KA7A 2YDUA 5HDEA 4H34A 2MBCA 2VTDA 3MVNA 4NNDA 3ZM6A 2CNHA 1PTTA 1XBOA 2CM3A 5KA9A 4QUNA 3BLUA 2PSZA 2QEPA 2H4VA 4ERCA 3M4UA 1LQFA 1YGRA 4HJQA 4TVVA 2F6YA 2B4OA 3BM8A 3HN7A 2ZN7A 4HRFA 4NWFA 2WTZA 2HVLA 1Q6SA 5KA0A 3QCMA 1C83A 2HC2A 2R0BA 2J16A 2CM2A 2P6XA 1U26A 4YR8B 1A5YA 3S4OA 2VEUA 1NWLA 1NZ7A 2WGPA 4R0TA 2CFVA 2GCAA 1L8KA 1JF7A 2DXPA 2I6JA 3QCNA 4B04A 2GC6A 4QUMA 2Q05A 1JLNA 2QBSA 5MMZB 2HCMA 2Y68A 3V0EA 1OEVA 1ZC0A 1AAXA 1SUGA 3UAGA 3F9BA 3EB1A 2RF6A 2F71A 3NRSA 4R30A 2AM2A 1G4WR 1ZCKA 2JFFA 1YFOA 2BGEA 3A5JA 2QDMA 1G1GA 3BLTA 2B4SA 3S3EA 4JMKA 3QCKA 5KACA 4ICZA 4C12A 4ZRTA 1OETA 4NX8A 1OEOX 2HY3A 3QCEA 4R0SA 1FPRA 3I7ZA 1NO6A 3F41A 3OLRA 2UUOA 1T49A 5KAAA 1WRMA 4J51A 1GFYA 1G1FA 3B7OA 3RGQA 5A5FA 1OEMX 1MKPA 3CM3A 3N0AA 4DGXA 2ZMMA 4GWFA 5K25A 2J17A 3D1OA 3PS5A 2FH7A 3S3FA 1C88A 4HJPA 2C7SA 2UUPA 3QCZA 3SMEA 2Y96A 2BZLA
chains in the Genus database with same CATH topology
4WOHA 1YGUA 4OHDA 2CNGA 3EZZA 4MBBA 3V0JA 2F6TA 5LXQB 3O5XA 1P15A 2H03A 2AHSA 1GWZA 3V0DA 3SR9A 2A3KA 2OC3A 2VEVA 2CNFA 1Q1MA 1OEUA 2A8BA 2BIJA 4QAHA 2VEXA 2I42A 2F6ZA 2F6WA 1C85A 4QBEA 5EHRA 1M3GA 2B4PA 2FJMA 1G4US 3O4TA 1XXVA 1XRIA 2CNIA 2GJTA 1YTWA 5AWXA 1V3AA 1BZCA 1Q6NA 2H4GA 2CMCA 1ZZWA 2I4EA 3QCGA 1X24A 3MOWA 1PTYA 3AWGA 2OUDA 4RI5A 4JMJA 2NTAA 1OESA 2GWOA 1ONYA 2BV5A 1YN9A 4NYHA 4BJOA 1Q6PA 1WCHA 3D44A 1PXHA 1PYNA 2QBQA 2G59A 1VHRA 3QCFA 4WU2A 3ZM3A 5BZZA 2ESBA 1PA1A 4BPCA 1OHDA 5M43A 1G7GA 5EHPA 2Q47A 3ZM1A 1PH0A 3BRHA 4JBCA 2QDCA 4WU3A 1FPZA 2IMGA 5K23A 1ECVA 1L8GA 1I57A 5GTJA 2P4DA 2NLKA 2E0TA 1XM2A 4RDDA 1PA9A 4OHLA 2I6MA 4OHHA 1C86A 3RGOA 2I1YA 2HNPA 3EU0A 2I6IA 3S3HA 4Y14A 1G7FA 5BUGA 2HB1A 1KAKA 2QBPA 2F6FA 2OZ5A 5KA8A 2PI7A 2SHPA 4RH9A 5KA2A 3GXHA 4PYHA 5I6VA 3OMHA 3NMEA 1XXPA 3ZM2A 3F81A 5KA4A 2QBRA 4D3QA 2B4UA 5BX1A 3ZMPA 3V0GA 1ZCLA 1NNYA 5KA3A 3QCLA 3I80A 4OHIA 2NT2A 4GE2A 1C84A 1I9SA 3QCJA 4RH5A 2I5XA 2I3UA 2F46A 2QDPA 2H4KA 4ZN5A 4YAAA 4GRYA 1RXDA 2I4HA 2GP0A 3V0FA 4GE5A 4KI9A 2B07A 1YPTA 4GFVA 4RKKA 5K24A 1PTUA 4GRZA 5BZXA 3S4EA 1G1HA 3O4UA 1D5RA 2M3VA 3LJ8A 1RPMA 3V0IA 4Z6BA 3A5KA 1Q6TA 3GXGA 3EMUA 4D3PA 1YTNA 3EAXA 5K22A 5KABA 4NWGA 2CM7A 2I6OA 4GS0A 1NL9A 3O4SA 3RO1A 3D1HA 5KADA 4RI4A 1EEOA 2FJNA 3MOZA 1Q6JA 5K9WA 3D9CA 1ONZA 2PBNA 2H02A 3V0HA 3QCBA 1T4JA 1FQ1A 3ZM0A 1LARA 1LYVA 1I9TA 4QAPA 5IBSA 2H04A 4RHGA 2PT0A 3AWEA 1OHEA 2BGDA 3F9AA 4GE6A 4D3RA 2QCTA 1WAXA 1U25A 3I36A 3ZV2A 1U24A 2CMAA 2NZ6A 5J8RA 2F70A 5KA1A 4GFUA 1PTVA 3H2XA 3MMJA 1QXKA 2PQ5A 3S3KA 4WTYA 3QCIA 2NV5A 1NWEA 4PVGA 2Y2FA 2CM8A 4IKCA 2QCJA 2F6VA 4DGPA 2I75A 2J16B 1KAVA 1C87A 4JNBA 4QBWA 2OOQA 1BZJA 1R6HA 2CJZA 2I6PA 2HXPA 2VEWA 2I3RA 4ZI4A 3F99A 3CWEA 1EENA 2NT7A 5IBMA 4OHEA 3O3LA 1QZ0A 1Q6MA 3QCHA 4I8NA 2CMBA 2B49A 1YWFA 4Y2EA 2JJDA 3RZ2A 3U96A 1T48A 2PA5A 1J4XA 2VEYA 3D1QA 2C46A 1YTSA 4H1OA 3QKQA 1BZHA 4AZ1A 5K9VA 4KYQA 1OHCA 2G6ZA 4S0GA 2HC1A 3QKPA 3QCCA 4KYRA 3ZMQA 1YZ4A 2I4GA 3AWFA 2B3OA 2AZRA 2HNQA 3D42A 3QCDA 2CNEA 5KA7A 2YDUA 5HDEA 4H34A 2MBCA 4NNDA 2CNHA 1PTTA 1XBOA 2CM3A 5KA9A 4QUNA 3BLUA 2PSZA 2QEPA 2H4VA 4ERCA 3M4UA 1LQFA 1YGRA 4HJQA 4TVVA 2F6YA 2B4OA 3BM8A 2ZN7A 4HRFA 4NWFA 2HVLA 1Q6SA 5KA0A 3QCMA 1C83A 2HC2A 2R0BA 2J16A 2CM2A 2P6XA 1U26A 4YR8B 1A5YA 3S4OA 2VEUA 1NWLA 1NZ7A 2WGPA 4R0TA 2CFVA 1L8KA 1JF7A 2DXPA 2I6JA 3QCNA 4B04A 4QUMA 2Q05A 1JLNA 2QBSA 5MMZB 2HCMA 3V0EA 1OEVA 1ZC0A 1AAXA 1SUGA 3F9BA 3EB1A 2RF6A 2F71A 4R30A 1G4WR 1ZCKA 1YFOA 2BGEA 3A5JA 2QDMA 1G1GA 3BLTA 2B4SA 3S3EA 4JMKA 3QCKA 5KACA 4ICZA 4ZRTA 1OETA 4NX8A 1OEOX 2HY3A 3QCEA 4R0SA 1FPRA 3I7ZA 1NO6A 3F41A 3OLRA 1T49A 5KAAA 1WRMA 4J51A 1GFYA 1G1FA 3B7OA 3RGQA 1OEMX 1MKPA 3CM3A 3N0AA 4DGXA 2ZMMA 4GWFA 5K25A 2J17A 3D1OA 3PS5A 2FH7A 3S3FA 1C88A 4HJPA 2C7SA 3SMEA 2Y96A 2BZLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WOH A;  1YGU A;  4OHD A;  2CNG A;  3EZZ A;  4MBB A;  3V0J A;  2F6T A;  5LXQ B;  3O5X A;  1P15 A;  2H03 A;  2AHS A;  1GWZ A;  3V0D A;  3SR9 A;  2A3K A;  2OC3 A;  2VEV A;  2CNF A;  1Q1M A;  1OEU A;  2A8B A;  2BIJ A;  4QAH A;  2VEX A;  2I42 A;  2F6Z A;  2F6W A;  1C85 A;  4QBE A;  5EHR A;  1M3G A;  2B4P A;  2FJM A;  1G4U S;  3O4T A;  1XXV A;  1XRI A;  2CNI A;  2GJT A;  1YTW A;  5AWX A;  1V3A A;  1BZC A;  1Q6N A;  2H4G A;  2CMC A;  1ZZW A;  2I4E A;  3QCG A;  1X24 A;  3MOW A;  1PTY A;  3AWG A;  2OUD A;  4RI5 A;  4JMJ A;  2NTA A;  1OES A;  2GWO A;  1ONY A;  2BV5 A;  1YN9 A;  4NYH A;  4BJO A;  1Q6P A;  1WCH A;  3D44 A;  1PXH A;  1PYN A;  2QBQ A;  2G59 A;  1VHR A;  3QCF A;  4WU2 A;  3ZM3 A;  5BZZ A;  2ESB A;  1PA1 A;  4BPC A;  1OHD A;  5M43 A;  1G7G A;  5EHP A;  2Q47 A;  3ZM1 A;  1PH0 A;  3BRH A;  4JBC A;  2QDC A;  4WU3 A;  1FPZ A;  2IMG A;  5K23 A;  1ECV A;  1L8G A;  1I57 A;  5GTJ A;  2P4D A;  2NLK A;  2E0T A;  1XM2 A;  4RDD A;  1PA9 A;  4OHL A;  2I6M A;  4OHH A;  1C86 A;  3RGO A;  2I1Y A;  2HNP A;  3EU0 A;  2I6I A;  3S3H A;  4Y14 A;  1G7F A;  5BUG A;  2HB1 A;  1KAK A;  2QBP A;  2F6F A;  2OZ5 A;  5KA8 A;  2PI7 A;  2SHP A;  4RH9 A;  5KA2 A;  3GXH A;  4PYH A;  5I6V A;  3OMH A;  3NME A;  1XXP A;  3ZM2 A;  3F81 A;  5KA4 A;  2QBR A;  4D3Q A;  2B4U A;  5BX1 A;  3ZMP A;  3V0G A;  1ZCL A;  1NNY A;  5KA3 A;  3QCL A;  3I80 A;  4OHI A;  2NT2 A;  4GE2 A;  1C84 A;  1I9S A;  3QCJ A;  4RH5 A;  2I5X A;  2I3U A;  2F46 A;  2QDP A;  2H4K A;  4ZN5 A;  4YAA A;  4GRY A;  1RXD A;  2I4H A;  2GP0 A;  3V0F A;  4GE5 A;  4KI9 A;  2B07 A;  1YPT A;  4GFV A;  4RKK A;  5K24 A;  1PTU A;  4GRZ A;  5BZX A;  3S4E A;  1G1H A;  3O4U A;  1D5R A;  2M3V A;  3LJ8 A;  1RPM A;  3V0I A;  4Z6B A;  3A5K A;  1Q6T A;  3GXG A;  3EMU A;  4D3P A;  1YTN A;  3EAX A;  5K22 A;  5KAB A;  4NWG A;  2CM7 A;  2I6O A;  4GS0 A;  1NL9 A;  3O4S A;  3RO1 A;  3D1H A;  5KAD A;  4RI4 A;  1EEO A;  2FJN A;  3MOZ A;  1Q6J A;  5K9W A;  3D9C A;  1ONZ A;  2PBN A;  2H02 A;  3V0H A;  3QCB A;  1T4J A;  1FQ1 A;  3ZM0 A;  1LAR A;  1LYV A;  1I9T A;  4QAP A;  5IBS A;  2H04 A;  4RHG A;  2PT0 A;  3AWE A;  1OHE A;  2BGD A;  3F9A A;  4GE6 A;  4D3R A;  2QCT A;  1WAX A;  1U25 A;  3I36 A;  3ZV2 A;  1U24 A;  2CMA A;  2NZ6 A;  5J8R A;  2F70 A;  5KA1 A;  4GFU A;  1PTV A;  3H2X A;  3MMJ A;  1QXK A;  2PQ5 A;  3S3K A;  4WTY A;  3QCI A;  2NV5 A;  1NWE A;  4PVG A;  2Y2F A;  2CM8 A;  4IKC A;  2QCJ A;  2F6V A;  4DGP A;  2I75 A;  2J16 B;  1KAV A;  1C87 A;  4JNB A;  4QBW A;  2OOQ A;  1BZJ A;  1R6H A;  2CJZ A;  2I6P A;  2HXP A;  2VEW A;  2I3R A;  4ZI4 A;  3F99 A;  3CWE A;  1EEN A;  2NT7 A;  5IBM A;  4OHE A;  3O3L A;  1QZ0 A;  1Q6M A;  3QCH A;  4I8N A;  2CMB A;  2B49 A;  1YWF A;  4Y2E A;  2JJD A;  3RZ2 A;  3U96 A;  1T48 A;  2PA5 A;  1J4X A;  2VEY A;  3D1Q A;  2C46 A;  1YTS A;  4H1O A;  3QKQ A;  1BZH A;  4AZ1 A;  5K9V A;  4KYQ A;  1OHC A;  2G6Z A;  4S0G A;  2HC1 A;  3QKP A;  3QCC A;  4KYR A;  3ZMQ A;  1YZ4 A;  2I4G A;  3AWF A;  2B3O A;  2AZR A;  2HNQ A;  3D42 A;  3QCD A;  2CNE A;  5KA7 A;  2YDU A;  5HDE A;  4H34 A;  2MBC A;  4NND A;  2CNH A;  1PTT A;  1XBO A;  2CM3 A;  5KA9 A;  4QUN A;  3BLU A;  2PSZ A;  2QEP A;  2H4V A;  4ERC A;  3M4U A;  1LQF A;  1YGR A;  4HJQ A;  4TVV A;  2F6Y A;  2B4O A;  3BM8 A;  2ZN7 A;  4HRF A;  4NWF A;  2HVL A;  1Q6S A;  5KA0 A;  3QCM A;  1C83 A;  2HC2 A;  2R0B A;  2J16 A;  2CM2 A;  2P6X A;  1U26 A;  4YR8 B;  1A5Y A;  3S4O A;  2VEU A;  1NWL A;  1NZ7 A;  2WGP A;  4R0T A;  2CFV A;  1L8K A;  1JF7 A;  2DXP A;  2I6J A;  3QCN A;  4B04 A;  4QUM A;  2Q05 A;  1JLN A;  2QBS A;  5MMZ B;  2HCM A;  3V0E A;  1OEV A;  1ZC0 A;  1AAX A;  1SUG A;  3F9B A;  3EB1 A;  2RF6 A;  2F71 A;  4R30 A;  1G4W R;  1ZCK A;  1YFO A;  2BGE A;  3A5J A;  2QDM A;  1G1G A;  3BLT A;  2B4S A;  3S3E A;  4JMK A;  3QCK A;  5KAC A;  4ICZ A;  4ZRT A;  1OET A;  4NX8 A;  1OEO X;  2HY3 A;  3QCE A;  4R0S A;  1FPR A;  3I7Z A;  1NO6 A;  3F41 A;  3OLR A;  1T49 A;  5KAA A;  1WRM A;  4J51 A;  1GFY A;  1G1F A;  3B7O A;  3RGQ A;  1OEM X;  1MKP A;  3CM3 A;  3N0A A;  4DGX A;  2ZMM A;  4GWF A;  5K25 A;  2J17 A;  3D1O A;  3PS5 A;  2FH7 A;  3S3F A;  1C88 A;  4HJP A;  2C7S A;  3SME A;  2Y96 A;  2BZL A; 
#chains in the Genus database with same CATH topology
 4WOH A;  1YGU A;  4OHD A;  2CNG A;  3EZZ A;  1EEH A;  4MBB A;  3V0J A;  2F6T A;  5LXQ B;  3O5X A;  1P15 A;  2H03 A;  2AHS A;  1GWZ A;  3V0D A;  3SR9 A;  2A3K A;  2OC3 A;  1E8C A;  1P3D A;  2VEV A;  2CNF A;  1Q1M A;  1OEU A;  2A8B A;  2BIJ A;  4QAH A;  2VEX A;  2I42 A;  2F6Z A;  2F6W A;  1C85 A;  4QBE A;  5EHR A;  1M3G A;  2B4P A;  2FJM A;  4UAG A;  1G4U S;  3O4T A;  4CVK A;  2Y66 A;  1XXV A;  1XRI A;  2CNI A;  2GJT A;  1YTW A;  5AWX A;  1V3A A;  1BZC A;  1Q6N A;  4BUB A;  2H4G A;  1JBV A;  2CMC A;  1ZZW A;  2I4E A;  3QCG A;  2UAG A;  1X24 A;  3MOW A;  2XPC A;  4C13 A;  1PTY A;  1JBW A;  1FGS A;  3AWG A;  3PYZ A;  4QF5 A;  2OUD A;  4RI5 A;  4JMJ A;  2NTA A;  1OES A;  2GWO A;  1ONY A;  3ZL8 A;  2BV5 A;  2AM1 A;  1YN9 A;  4NYH A;  4BJO A;  1Q6P A;  1WCH A;  3LK7 A;  3D44 A;  1PXH A;  1PYN A;  2QBQ A;  2G59 A;  2VOS A;  1VHR A;  3QCF A;  4WU2 A;  3ZM3 A;  5BZZ A;  2ESB A;  1PA1 A;  4BPC A;  1OHD A;  5M43 A;  1G7G A;  5EHP A;  2Q47 A;  2Y1O A;  3ZM1 A;  1PH0 A;  3BRH A;  4JBC A;  2QDC A;  4WU3 A;  1FPZ A;  2IMG A;  2XJA A;  5K23 A;  1ECV A;  1L8G A;  1I57 A;  5GTJ A;  2P4D A;  2NLK A;  2E0T A;  1XM2 A;  4RDD A;  1PA9 A;  4OHL A;  2I6M A;  1GQQ A;  2GC5 A;  4OHH A;  1C86 A;  3RGO A;  2I1Y A;  2HNP A;  3EU0 A;  5A5E A;  2I6I A;  3S3H A;  4CVL A;  4Y14 A;  1G7F A;  5BUG A;  2HB1 A;  1KAK A;  2QBP A;  2F6F A;  2OZ5 A;  5KA8 A;  2PI7 A;  2SHP A;  4RH9 A;  4ZIY A;  5KA2 A;  3GXH A;  4PYH A;  5I6V A;  3OMH A;  3NME A;  1XXP A;  3ZM2 A;  3F81 A;  5KA4 A;  2QBR A;  4D3Q A;  2B4U A;  5BX1 A;  3ZMP A;  3V0G A;  1ZCL A;  2VOR A;  1NNY A;  5KA3 A;  3QCL A;  3I80 A;  4OHI A;  2NT2 A;  3ZM5 A;  4GE2 A;  1C84 A;  1I9S A;  3QCJ A;  4RH5 A;  2I5X A;  2I3U A;  2F46 A;  2JFH A;  2QDP A;  2H4K A;  4ZN5 A;  4YAA A;  4GRY A;  1RXD A;  2I4H A;  2GP0 A;  1J6U A;  3V0F A;  4GE5 A;  4KI9 A;  2B07 A;  1YPT A;  4GFV A;  4RKK A;  5K24 A;  1PTU A;  4GRZ A;  5BZX A;  3S4E A;  1G1H A;  3O4U A;  1D5R A;  2M3V A;  3LJ8 A;  1RPM A;  3V0I A;  4Z6B A;  1UAG A;  3A5K A;  1Q6T A;  3GXG A;  3EMU A;  2WJP A;  1YTN A;  4D3P A;  3EAX A;  5K22 A;  5KAB A;  4NWG A;  2CM7 A;  2I6O A;  4GS0 A;  1NL9 A;  3O4S A;  3RO1 A;  3D1H A;  3N2A A;  5KAD A;  4RI4 A;  1EEO A;  2FJN A;  3MOZ A;  1Q6J A;  5K9W A;  3D9C A;  1ONZ A;  2PBN A;  2H02 A;  3V0H A;  3QCB A;  1T4J A;  1FQ1 A;  3ZM0 A;  1LAR A;  1LYV A;  1I9T A;  2JFG A;  4QAP A;  5IBS A;  2H04 A;  4RHG A;  2PT0 A;  3AWE A;  1OHE A;  2BGD A;  3F9A A;  4GE6 A;  4D3R A;  2X5O A;  1GG4 A;  2VTE A;  2QCT A;  1WAX A;  1U25 A;  3I36 A;  1O5Z A;  3ZV2 A;  1U24 A;  2CMA A;  2NZ6 A;  5J8R A;  2F70 A;  5KA1 A;  4GFU A;  1PTV A;  3H2X A;  3MMJ A;  1QXK A;  2PQ5 A;  1W78 A;  4BUC A;  3S3K A;  4WTY A;  3QCI A;  2NV5 A;  1NWE A;  4PVG A;  2Y2F A;  2CM8 A;  4IKC A;  2QCJ A;  2F6V A;  4DGP A;  2I75 A;  2J16 B;  1KAV A;  1C87 A;  4JNB A;  4QBW A;  1GQY A;  2OOQ A;  1BZJ A;  1R6H A;  2CJZ A;  2I6P A;  2HXP A;  2VEW A;  2I3R A;  4ZI4 A;  3F99 A;  3CWE A;  1EEN A;  2NT7 A;  5IBM A;  4OHE A;  3O3L A;  1QZ0 A;  2Y67 A;  4HV4 A;  1Q6M A;  3QCH A;  1E0D A;  4I8N A;  2CMB A;  1W7K A;  2B49 A;  1YWF A;  4Y2E A;  2JJD A;  3RZ2 A;  3U96 A;  1T48 A;  2PA5 A;  1P31 A;  1J4X A;  2VEY A;  3D1Q A;  2C46 A;  1YTS A;  4H1O A;  3QKQ A;  1BZH A;  4CVM A;  4AZ1 A;  5K9V A;  4KYQ A;  1OHC A;  4QDI A;  2GCB A;  2G6Z A;  4S0G A;  2HC1 A;  3QKP A;  3QCC A;  4KYR A;  3ZMQ A;  1YZ4 A;  2I4G A;  3AWF A;  2B3O A;  2AZR A;  2F00 A;  2HNQ A;  3D42 A;  3QCD A;  2CNE A;  5KA7 A;  2YDU A;  5HDE A;  4H34 A;  2MBC A;  2VTD A;  3MVN A;  4NND A;  3ZM6 A;  2CNH A;  1PTT A;  1XBO A;  2CM3 A;  5KA9 A;  4QUN A;  3BLU A;  2PSZ A;  2QEP A;  2H4V A;  4ERC A;  3M4U A;  1LQF A;  1YGR A;  4HJQ A;  4TVV A;  2F6Y A;  2B4O A;  3BM8 A;  3HN7 A;  2ZN7 A;  4HRF A;  4NWF A;  2WTZ A;  2HVL A;  1Q6S A;  5KA0 A;  3QCM A;  1C83 A;  2HC2 A;  2R0B A;  2J16 A;  2CM2 A;  2P6X A;  1U26 A;  4YR8 B;  1A5Y A;  3S4O A;  2VEU A;  1NWL A;  1NZ7 A;  2WGP A;  4R0T A;  2CFV A;  2GCA A;  1L8K A;  1JF7 A;  2DXP A;  2I6J A;  3QCN A;  4B04 A;  2GC6 A;  4QUM A;  2Q05 A;  1JLN A;  2QBS A;  5MMZ B;  2HCM A;  2Y68 A;  3V0E A;  1OEV A;  1ZC0 A;  1AAX A;  1SUG A;  3UAG A;  3F9B A;  3EB1 A;  2RF6 A;  2F71 A;  3NRS A;  4R30 A;  2AM2 A;  1G4W R;  1ZCK A;  2JFF A;  1YFO A;  2BGE A;  3A5J A;  2QDM A;  1G1G A;  3BLT A;  2B4S A;  3S3E A;  4JMK A;  3QCK A;  5KAC A;  4ICZ A;  4C12 A;  4ZRT A;  1OET A;  4NX8 A;  1OEO X;  2HY3 A;  3QCE A;  4R0S A;  1FPR A;  3I7Z A;  1NO6 A;  3F41 A;  3OLR A;  2UUO A;  1T49 A;  5KAA A;  1WRM A;  4J51 A;  1GFY A;  1G1F A;  3B7O A;  3RGQ A;  5A5F A;  1OEM X;  1MKP A;  3CM3 A;  3N0A A;  4DGX A;  2ZMM A;  4GWF A;  5K25 A;  2J17 A;  3D1O A;  3PS5 A;  2FH7 A;  3S3F A;  1C88 A;  4HJP A;  2C7S A;  2UUP A;  3QCZ A;  3SME A;  2Y96 A;  2BZL A; 
#chains in the Genus database with same CATH homology
 4WOH A;  1YGU A;  4OHD A;  2CNG A;  3EZZ A;  4MBB A;  3V0J A;  2F6T A;  5LXQ B;  3O5X A;  1P15 A;  2H03 A;  2AHS A;  1GWZ A;  3V0D A;  3SR9 A;  2A3K A;  2OC3 A;  2VEV A;  2CNF A;  1Q1M A;  1OEU A;  2A8B A;  2BIJ A;  4QAH A;  2VEX A;  2I42 A;  2F6Z A;  2F6W A;  1C85 A;  4QBE A;  5EHR A;  1M3G A;  2B4P A;  2FJM A;  1G4U S;  3O4T A;  1XXV A;  1XRI A;  2CNI A;  2GJT A;  1YTW A;  5AWX A;  1V3A A;  1BZC A;  1Q6N A;  2H4G A;  2CMC A;  1ZZW A;  2I4E A;  3QCG A;  1X24 A;  3MOW A;  1PTY A;  3AWG A;  2OUD A;  4RI5 A;  4JMJ A;  2NTA A;  1OES A;  2GWO A;  1ONY A;  2BV5 A;  1YN9 A;  4NYH A;  4BJO A;  1Q6P A;  1WCH A;  3D44 A;  1PXH A;  1PYN A;  2QBQ A;  2G59 A;  1VHR A;  3QCF A;  4WU2 A;  3ZM3 A;  5BZZ A;  2ESB A;  1PA1 A;  4BPC A;  1OHD A;  5M43 A;  1G7G A;  5EHP A;  2Q47 A;  3ZM1 A;  1PH0 A;  3BRH A;  4JBC A;  2QDC A;  4WU3 A;  1FPZ A;  2IMG A;  5K23 A;  1ECV A;  1L8G A;  1I57 A;  5GTJ A;  2P4D A;  2NLK A;  2E0T A;  1XM2 A;  4RDD A;  1PA9 A;  4OHL A;  2I6M A;  4OHH A;  1C86 A;  3RGO A;  2I1Y A;  2HNP A;  3EU0 A;  2I6I A;  3S3H A;  4Y14 A;  1G7F A;  5BUG A;  2HB1 A;  1KAK A;  2QBP A;  2F6F A;  2OZ5 A;  5KA8 A;  2PI7 A;  2SHP A;  4RH9 A;  5KA2 A;  3GXH A;  4PYH A;  5I6V A;  3OMH A;  3NME A;  1XXP A;  3ZM2 A;  3F81 A;  5KA4 A;  2QBR A;  4D3Q A;  2B4U A;  5BX1 A;  3ZMP A;  3V0G A;  1ZCL A;  1NNY A;  5KA3 A;  3QCL A;  3I80 A;  4OHI A;  2NT2 A;  4GE2 A;  1C84 A;  1I9S A;  3QCJ A;  4RH5 A;  2I5X A;  2I3U A;  2F46 A;  2QDP A;  2H4K A;  4ZN5 A;  4YAA A;  4GRY A;  1RXD A;  2I4H A;  2GP0 A;  3V0F A;  4GE5 A;  4KI9 A;  2B07 A;  1YPT A;  4GFV A;  4RKK A;  5K24 A;  1PTU A;  4GRZ A;  5BZX A;  3S4E A;  1G1H A;  3O4U A;  1D5R A;  2M3V A;  3LJ8 A;  1RPM A;  3V0I A;  4Z6B A;  3A5K A;  1Q6T A;  3GXG A;  3EMU A;  4D3P A;  1YTN A;  3EAX A;  5K22 A;  5KAB A;  4NWG A;  2CM7 A;  2I6O A;  4GS0 A;  1NL9 A;  3O4S A;  3RO1 A;  3D1H A;  5KAD A;  4RI4 A;  1EEO A;  2FJN A;  3MOZ A;  1Q6J A;  5K9W A;  3D9C A;  1ONZ A;  2PBN A;  2H02 A;  3V0H A;  3QCB A;  1T4J A;  1FQ1 A;  3ZM0 A;  1LAR A;  1LYV A;  1I9T A;  4QAP A;  5IBS A;  2H04 A;  4RHG A;  2PT0 A;  3AWE A;  1OHE A;  2BGD A;  3F9A A;  4GE6 A;  4D3R A;  2QCT A;  1WAX A;  1U25 A;  3I36 A;  3ZV2 A;  1U24 A;  2CMA A;  2NZ6 A;  5J8R A;  2F70 A;  5KA1 A;  4GFU A;  1PTV A;  3H2X A;  3MMJ A;  1QXK A;  2PQ5 A;  3S3K A;  4WTY A;  3QCI A;  2NV5 A;  1NWE A;  4PVG A;  2Y2F A;  2CM8 A;  4IKC A;  2QCJ A;  2F6V A;  4DGP A;  2I75 A;  2J16 B;  1KAV A;  1C87 A;  4JNB A;  4QBW A;  2OOQ A;  1BZJ A;  1R6H A;  2CJZ A;  2I6P A;  2HXP A;  2VEW A;  2I3R A;  4ZI4 A;  3F99 A;  3CWE A;  1EEN A;  2NT7 A;  5IBM A;  4OHE A;  3O3L A;  1QZ0 A;  1Q6M A;  3QCH A;  4I8N A;  2CMB A;  2B49 A;  1YWF A;  4Y2E A;  2JJD A;  3RZ2 A;  3U96 A;  1T48 A;  2PA5 A;  1J4X A;  2VEY A;  3D1Q A;  2C46 A;  1YTS A;  4H1O A;  3QKQ A;  1BZH A;  4AZ1 A;  5K9V A;  4KYQ A;  1OHC A;  2G6Z A;  4S0G A;  2HC1 A;  3QKP A;  3QCC A;  4KYR A;  3ZMQ A;  1YZ4 A;  2I4G A;  3AWF A;  2B3O A;  2AZR A;  2HNQ A;  3D42 A;  3QCD A;  2CNE A;  5KA7 A;  2YDU A;  5HDE A;  4H34 A;  2MBC A;  4NND A;  2CNH A;  1PTT A;  1XBO A;  2CM3 A;  5KA9 A;  4QUN A;  3BLU A;  2PSZ A;  2QEP A;  2H4V A;  4ERC A;  3M4U A;  1LQF A;  1YGR A;  4HJQ A;  4TVV A;  2F6Y A;  2B4O A;  3BM8 A;  2ZN7 A;  4HRF A;  4NWF A;  2HVL A;  1Q6S A;  5KA0 A;  3QCM A;  1C83 A;  2HC2 A;  2R0B A;  2J16 A;  2CM2 A;  2P6X A;  1U26 A;  4YR8 B;  1A5Y A;  3S4O A;  2VEU A;  1NWL A;  1NZ7 A;  2WGP A;  4R0T A;  2CFV A;  1L8K A;  1JF7 A;  2DXP A;  2I6J A;  3QCN A;  4B04 A;  4QUM A;  2Q05 A;  1JLN A;  2QBS A;  5MMZ B;  2HCM A;  3V0E A;  1OEV A;  1ZC0 A;  1AAX A;  1SUG A;  3F9B A;  3EB1 A;  2RF6 A;  2F71 A;  4R30 A;  1G4W R;  1ZCK A;  1YFO A;  2BGE A;  3A5J A;  2QDM A;  1G1G A;  3BLT A;  2B4S A;  3S3E A;  4JMK A;  3QCK A;  5KAC A;  4ICZ A;  4ZRT A;  1OET A;  4NX8 A;  1OEO X;  2HY3 A;  3QCE A;  4R0S A;  1FPR A;  3I7Z A;  1NO6 A;  3F41 A;  3OLR A;  1T49 A;  5KAA A;  1WRM A;  4J51 A;  1GFY A;  1G1F A;  3B7O A;  3RGQ A;  1OEM X;  1MKP A;  3CM3 A;  3N0A A;  4DGX A;  2ZMM A;  4GWF A;  5K25 A;  2J17 A;  3D1O A;  3PS5 A;  2FH7 A;  3S3F A;  1C88 A;  4HJP A;  2C7S A;  3SME A;  2Y96 A;  2BZL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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