3SMMA

Crystal structure of human 14-3-3 sigma c38n/n166h in complex with task-3 peptide and stabilizer fusicoccin j aglycone
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
236
structure length
236
Chain Sequence
GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSNEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTHPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.
pubmed doi rcsb
molecule tags Peptide binding protein
source organism Homo sapiens
molecule keywords 14-3-3 protein sigma
total genus 103
structure length 236
sequence length 236
ec nomenclature
pdb deposition date 2011-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 3smmA00
3P1OA 3P1QA 5BY9A 5BTVA 4DHPA 5F74A 5HF3A 1O9CA 4J6SA 1A38A 4E2EA 2C1NA 5D3FA 3SMKA 1YZ5A 2O98A 3MHRA 3CU8A 5LVZA 4ZQ0A 4DHMA 2NPMA 2C1JA 3O8IA 2C74A 3UX0A 4N7GA 1O9FA 4FJ3A 3LW1A 4O46A 5LHOA 3P1NA 3SMNA 2C63A 2BTPA 3P1RA 4DHNA 3UALA 5D2DA 5EXAA 3IQJA 3AXYC 5D3EA 5J31A 3M51A 3RDHA 1A37A 4DX0A 3SMMA 3IQUA 3EFZA 3IQVA 1QJAA 3UBWA 2BR9A 2O8PA 4N84A 4DHTA 4F7RA 4Y5IA 4HKCA 2WH0A 4DNKA 4BG6A 3UZDA 4DHRA 5EWZA 3SPRA 4DATA 1O9DA 4DAUA 2V7DA 4JC3A 4Y32A 3P1SA 4DHOA 3U9XA 3SP5A 3SMOA 4WRQA 4Y3BA 1A4OA 5LX2A 3T0LA 3M50A 1O9EA 3SMLA 3T0MA 3P1PA 4FL5A 2C23A 4JDDA 4IHLA 4N7YA 4DHSA 4DHQA 4IEAA 4GNTA 2B05A 4QLIA 5LU1A 4ZDRA 1YWTA 1QJBA 4DHUA 4FR3A 5IQPA 2O02A 2BQ0A 5LU2A 3NKXA 3E6YA 1IB1A
chains in the Genus database with same CATH superfamily
3P1OA 3P1QA 5BY9A 5BTVA 4DHPA 5F74A 5HF3A 1O9CA 4J6SA 1A38A 4E2EA 2C1NA 5D3FA 3SMKA 3CQGA 1YZ5A 2O98A 3MHRA 3CU8A 5LVZA 4ZQ0A 4DHMA 2NPMA 2C1JA 3O8IA 2C74A 3UX0A 4N7GA 1O9FA 4FJ3A 3LW1A 4O46A 1JI6A 5LHOA 3P1NA 3SMNA 2C63A 4ARYA 2BTPA 1W99A 3P1RA 4ARXA 1CIYA 4DHNA 3EB7A 3UALA 5D2DA 5EXAA 3IQJA 3AXYC 5D3EA 5J31A 3M51A 3RDHA 1A37A 4DX0A 3SMMA 1DLCA 3X0UA 1URJA 3IQUA 3EFZA 3IQVA 1QJAA 3UBWA 2BR9A 2O8PA 4MOAA 4N84A 4DHTA 4F7RA 4Y5IA 4HKCA 2WH0A 4DNKA 3I4RA 4BG6A 3UZDA 4DHRA 5EWZA 4QX0A 3SPRA 4DATA 1O9DA 4DAUA 4QX2A 2V7DA 4JC3A 4Y32A 3P1SA 3ZHEB 4DHOA 3U9XA 3SP5A 3SMOA 4WRQA 4W8JA 3CQCA 4Y3BA 2C9KA 1A4OA 5LX2A 3T0LA 3M50A 1O9EA 3SMLA 3T0MA 1I5PA 3P1PA 4D8MA 4FL5A 2C23A 4JDDA 4IHLA 4N7YA 4QX1A 4DHSA 4DHQA 4IEAA 4GNTA 4QX3A 2B05A 4QLIA 5LU1A 4ZDRA 1YWTA 1QJBA 4DHUA 1S2XA 4FR3A 5IQPA 2O02A 2BQ0A 5LU2A 3NKXA 3E6YA 1IB1A
chains in the Genus database with same CATH topology
3P1OA 3P1QA 5BY9A 5BTVA 4DHPA 5F74A 5HF3A 1O9CA 4J6SA 1A38A 4E2EA 2C1NA 5D3FA 3SMKA 1YZ5A 2O98A 3MHRA 3CU8A 5LVZA 4ZQ0A 4DHMA 2NPMA 2C1JA 3O8IA 2C74A 3UX0A 4N7GA 1O9FA 4FJ3A 3LW1A 4O46A 5LHOA 3P1NA 3SMNA 2C63A 2BTPA 3P1RA 4DHNA 3UALA 5D2DA 5EXAA 3IQJA 3AXYC 5D3EA 5J31A 3M51A 3RDHA 1A37A 4DX0A 3SMMA 3IQUA 3EFZA 3IQVA 1QJAA 3UBWA 2BR9A 2O8PA 4N84A 4DHTA 4F7RA 4Y5IA 4HKCA 2WH0A 4DNKA 4BG6A 3UZDA 4DHRA 5EWZA 3SPRA 4DATA 1O9DA 4DAUA 2V7DA 4JC3A 4Y32A 3P1SA 4DHOA 3U9XA 3SP5A 3SMOA 4WRQA 4Y3BA 1A4OA 5LX2A 3T0LA 3M50A 1O9EA 3SMLA 3T0MA 3P1PA 4FL5A 2C23A 4JDDA 4IHLA 4N7YA 4DHSA 4DHQA 4IEAA 4GNTA 2B05A 4QLIA 5LU1A 4ZDRA 1YWTA 1QJBA 4DHUA 4FR3A 5IQPA 2O02A 2BQ0A 5LU2A 3NKXA 3E6YA 1IB1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P1O A;  3P1Q A;  5BY9 A;  5BTV A;  4DHP A;  5F74 A;  5HF3 A;  1O9C A;  4J6S A;  1A38 A;  4E2E A;  2C1N A;  5D3F A;  3SMK A;  1YZ5 A;  2O98 A;  3MHR A;  3CU8 A;  5LVZ A;  4ZQ0 A;  4DHM A;  2NPM A;  2C1J A;  3O8I A;  2C74 A;  3UX0 A;  4N7G A;  1O9F A;  4FJ3 A;  3LW1 A;  4O46 A;  5LHO A;  3P1N A;  3SMN A;  2C63 A;  2BTP A;  3P1R A;  4DHN A;  3UAL A;  5D2D A;  5EXA A;  3IQJ A;  3AXY C;  5D3E A;  5J31 A;  3M51 A;  3RDH A;  1A37 A;  4DX0 A;  3SMM A;  3IQU A;  3EFZ A;  3IQV A;  1QJA A;  3UBW A;  2BR9 A;  2O8P A;  4N84 A;  4DHT A;  4F7R A;  4Y5I A;  4HKC A;  2WH0 A;  4DNK A;  4BG6 A;  3UZD A;  4DHR A;  5EWZ A;  3SPR A;  4DAT A;  1O9D A;  4DAU A;  2V7D A;  4JC3 A;  4Y32 A;  3P1S A;  4DHO A;  3U9X A;  3SP5 A;  3SMO A;  4WRQ A;  4Y3B A;  1A4O A;  5LX2 A;  3T0L A;  3M50 A;  1O9E A;  3SML A;  3T0M A;  3P1P A;  4FL5 A;  2C23 A;  4JDD A;  4IHL A;  4N7Y A;  4DHS A;  4DHQ A;  4IEA A;  4GNT A;  2B05 A;  4QLI A;  5LU1 A;  4ZDR A;  1YWT A;  1QJB A;  4DHU A;  4FR3 A;  5IQP A;  2O02 A;  2BQ0 A;  5LU2 A;  3NKX A;  3E6Y A;  1IB1 A; 
#chains in the Genus database with same CATH topology
 3P1O A;  3P1Q A;  5BY9 A;  5BTV A;  4DHP A;  5F74 A;  5HF3 A;  1O9C A;  4J6S A;  1A38 A;  4E2E A;  2C1N A;  5D3F A;  3SMK A;  3CQG A;  1YZ5 A;  2O98 A;  3MHR A;  3CU8 A;  5LVZ A;  4ZQ0 A;  4DHM A;  2NPM A;  2C1J A;  3O8I A;  2C74 A;  3UX0 A;  4N7G A;  1O9F A;  4FJ3 A;  3LW1 A;  4O46 A;  1JI6 A;  5LHO A;  3P1N A;  3SMN A;  2C63 A;  4ARY A;  2BTP A;  1W99 A;  3P1R A;  4ARX A;  1CIY A;  4DHN A;  3EB7 A;  3UAL A;  5D2D A;  5EXA A;  3IQJ A;  3AXY C;  5D3E A;  5J31 A;  3M51 A;  3RDH A;  1A37 A;  4DX0 A;  3SMM A;  1DLC A;  3X0U A;  1URJ A;  3IQU A;  3EFZ A;  3IQV A;  1QJA A;  3UBW A;  2BR9 A;  2O8P A;  4MOA A;  4N84 A;  4DHT A;  4F7R A;  4Y5I A;  4HKC A;  2WH0 A;  4DNK A;  3I4R A;  4BG6 A;  3UZD A;  4DHR A;  5EWZ A;  4QX0 A;  3SPR A;  4DAT A;  1O9D A;  4DAU A;  4QX2 A;  2V7D A;  4JC3 A;  4Y32 A;  3P1S A;  3ZHE B;  4DHO A;  3U9X A;  3SP5 A;  3SMO A;  4WRQ A;  4W8J A;  3CQC A;  4Y3B A;  2C9K A;  1A4O A;  5LX2 A;  3T0L A;  3M50 A;  1O9E A;  3SML A;  3T0M A;  1I5P A;  3P1P A;  4D8M A;  4FL5 A;  2C23 A;  4JDD A;  4IHL A;  4N7Y A;  4QX1 A;  4DHS A;  4DHQ A;  4IEA A;  4GNT A;  4QX3 A;  2B05 A;  4QLI A;  5LU1 A;  4ZDR A;  1YWT A;  1QJB A;  4DHU A;  1S2X A;  4FR3 A;  5IQP A;  2O02 A;  2BQ0 A;  5LU2 A;  3NKX A;  3E6Y A;  1IB1 A; 
#chains in the Genus database with same CATH homology
 3P1O A;  3P1Q A;  5BY9 A;  5BTV A;  4DHP A;  5F74 A;  5HF3 A;  1O9C A;  4J6S A;  1A38 A;  4E2E A;  2C1N A;  5D3F A;  3SMK A;  1YZ5 A;  2O98 A;  3MHR A;  3CU8 A;  5LVZ A;  4ZQ0 A;  4DHM A;  2NPM A;  2C1J A;  3O8I A;  2C74 A;  3UX0 A;  4N7G A;  1O9F A;  4FJ3 A;  3LW1 A;  4O46 A;  5LHO A;  3P1N A;  3SMN A;  2C63 A;  2BTP A;  3P1R A;  4DHN A;  3UAL A;  5D2D A;  5EXA A;  3IQJ A;  3AXY C;  5D3E A;  5J31 A;  3M51 A;  3RDH A;  1A37 A;  4DX0 A;  3SMM A;  3IQU A;  3EFZ A;  3IQV A;  1QJA A;  3UBW A;  2BR9 A;  2O8P A;  4N84 A;  4DHT A;  4F7R A;  4Y5I A;  4HKC A;  2WH0 A;  4DNK A;  4BG6 A;  3UZD A;  4DHR A;  5EWZ A;  3SPR A;  4DAT A;  1O9D A;  4DAU A;  2V7D A;  4JC3 A;  4Y32 A;  3P1S A;  4DHO A;  3U9X A;  3SP5 A;  3SMO A;  4WRQ A;  4Y3B A;  1A4O A;  5LX2 A;  3T0L A;  3M50 A;  1O9E A;  3SML A;  3T0M A;  3P1P A;  4FL5 A;  2C23 A;  4JDD A;  4IHL A;  4N7Y A;  4DHS A;  4DHQ A;  4IEA A;  4GNT A;  2B05 A;  4QLI A;  5LU1 A;  4ZDR A;  1YWT A;  1QJB A;  4DHU A;  4FR3 A;  5IQP A;  2O02 A;  2BQ0 A;  5LU2 A;  3NKX A;  3E6Y A;  1IB1 A; 
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similar chains in the Genus database (?% sequence similarity)
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