3SW0X

Structure of the c-terminal region (modules 18-20) of complement regulator factor h
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
186
structure length
186
Chain Sequence
GTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH).
pubmed doi rcsb
molecule keywords Complement factor H
molecule tags Immune system
source organism Homo sapiens
total genus 34
structure length 186
sequence length 186
ec nomenclature
pdb deposition date 2011-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3sw0X01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3sw0X02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3sw0X03
2JRAA 1HFIA 2RLPA 1E88A 1FBRA 1ZJKA 3L89M 4WJG2 2CKUA 2JGXA 1SRZA 2RKYA 1QO6A 2LOJA 2XWBF 1GKNA 4J38B 1E5GA 2JGWA 2XWJI 4AYEA 1OK1A 3GOVA 3OP8A 4KKDA 3M7PA 4JHSA 3O8EB 1QGBA 1GPZA 2RL0A 1H2QP 5HZPB 1H03P 4C16A 2BZMA 2V8EA 1OK3A 3ZD2A 2EC3A 1C1ZA 2A55A 3T5OA 4FXGG 4MUCA 3ERBA 5JPMG 2XRDA 2RKZA 5FO8C 1U5MA 1GKGA 4F4OC 3OXUD 1OJYA 1TPMA 2KRIA 1MD8A 1OJVA 2W81A 2XQWC 2KMSA 1VVCA 2EHFA 2MCZA 4LOSA 5HYUB 1O9AA 1SS2A 1CKLA 3KXVA 2IZ4A 4AYMA 1HFHA 4B2SA 2QY0A 5I0QB 4A5WB 4IGDA 4K12A 1Q3XA 5HYPA 3R62A 1MD7A 4YNXA 2YRAA 3IU3I 3CALA 3TVJA 1OK9A 3ZRZA 4B2RA 4ZH1D 2CG6A 2G7IA 1TPNA 1G4FA 4CSYA 1VVDA 2B5ID 1Z92B 1H04P 3IX0A 4LOTA 2MCYA 1OJWA 2IZ3A 3SW0X 4AYIA 1HCCA 4DJZA 2W80A 3OEDC 3EJHA 1GHQB 1E8BA 1TPGA 3MQLA 5HYTB 1H2PP 3RJ3D 1LY2A 3KZJA 1ELVA 2YBYA 3NFPI 1NWVA 1OK2A 2RLQA 1G4GA 1UOTP 2WIIC 3ZD1A 2O39C 4PZ5A 3INBC 2XRBA 3GXEA 1QUBA 4AYDA 1PPQA 4ONTD 2ERJA 2UWNA 2CG7A
chains in the Genus database with same CATH superfamily
2JRAA 1HFIA 2RLPA 1E88A 3F6KA 1FBRA 1ZJKA 3L89M 4WJG2 3ZLDA 2CKUA 3K3TA 2JGXA 1SRZA 3FGRA 2ZYCA 2RKYA 1QO6A 2LOJA 2XWBF 1GKNA 4J38B 1E5GA 4YIZA 2JGWA 2XWJI 4AYEA 1OK1A 3GOVA 3OP8A 2Y8RA 4KKDA 3M7PA 4JHSA 3O8EB 1QGBA 1GPZA 2I2LA 2RL0A 1H2QP 5HZPB 1H03P 4C16A 2BZMA 2V8EA 1OK3A 3ZD2A 2X2ZA 2EC3A 1C1ZA 2A55A 3CI0J 3T5OA 4APLA 4FXGG 3FGTA 3ERBA 4MUCA 5JPMG 2XRDA 3WSYA 3ZLEA 2RKZA 5FO8C 1U5MA 1GKGA 4F4OC 3OXUD 1OJYA 1TPMA 2KRIA 1MD8A 1OJVA 2W81A 1RLHA 2XQWC 2KMSA 1VVCA 2EHFA 2MCZA 4LOSA 5HYUB 1O9AA 5DN5A 1SS2A 1CKLA 3KXVA 2IZ4A 4AYMA 1HFHA 4B2SA 2QY0A 5I0QB 4A5WB 4IGDA 4K12A 1Q3XA 5HYPA 3R62A 1MD7A 4YNXA 2YRAA 3IU3I 5DN4A 3CALA 3TVJA 1OK9A 3ZRZA 4B2RA 4ZH1D 2CG6A 2G7IA 1TPNA 4N7EA 1G4FA 4CSYA 1VVDA 2B5ID 1Z92B 1H04P 3WSXA 3IX0A 4LOTA 2MCYA 1OJWA 2IZ3A 3SW0X 4AYIA 3VWOA 1HCCA 4DJZA 2W80A 3OEDC 3EJHA 1GHQB 3NJAA 1E8BA 1TPGA 3MQLA 5HYTB 1H2PP 3RJ3D 1LY2A 3KZJA 1ELVA 2YBYA 3NFPI 1NWVA 1OK2A 2RLQA 1G4GA 1UOTP 2WIIC 3ZD1A 2O39C 4MSLA 4PZ5A 2Y8TA 3INBC 4BWCA 2XRBA 3GXEA 4PO7A 1QUBA 2Y8SA 4AYDA 1PPQA 4ONTD 2ERJA 2UWNA 2CG7A
chains in the Genus database with same CATH topology
2JRAA 1HFIA 2RLPA 1E88A 1FBRA 1ZJKA 3L89M 4WJG2 2CKUA 2JGXA 1SRZA 2RKYA 1QO6A 2LOJA 2XWBF 1GKNA 4J38B 1E5GA 2JGWA 2XWJI 4AYEA 1OK1A 3GOVA 3OP8A 4KKDA 3M7PA 4JHSA 3O8EB 1QGBA 1GPZA 2RL0A 1H2QP 5HZPB 1H03P 4C16A 2BZMA 2V8EA 1OK3A 3ZD2A 2EC3A 1C1ZA 2A55A 3T5OA 4FXGG 4MUCA 3ERBA 5JPMG 2XRDA 2RKZA 5FO8C 1U5MA 1GKGA 4F4OC 3OXUD 1OJYA 1TPMA 2KRIA 1MD8A 1OJVA 2W81A 2XQWC 2KMSA 1VVCA 2EHFA 2MCZA 4LOSA 5HYUB 1O9AA 1SS2A 1CKLA 3KXVA 2IZ4A 4AYMA 1HFHA 4B2SA 2QY0A 5I0QB 4A5WB 4IGDA 4K12A 1Q3XA 5HYPA 3R62A 1MD7A 4YNXA 2YRAA 3IU3I 3CALA 3TVJA 1OK9A 3ZRZA 4B2RA 4ZH1D 2CG6A 2G7IA 1TPNA 1G4FA 4CSYA 1VVDA 2B5ID 1Z92B 1H04P 3IX0A 4LOTA 2MCYA 1OJWA 2IZ3A 3SW0X 4AYIA 1HCCA 4DJZA 2W80A 3OEDC 3EJHA 1GHQB 1E8BA 1TPGA 3MQLA 5HYTB 1H2PP 3RJ3D 1LY2A 3KZJA 1ELVA 2YBYA 3NFPI 1NWVA 1OK2A 2RLQA 1G4GA 1UOTP 2WIIC 3ZD1A 2O39C 4PZ5A 3INBC 2XRBA 3GXEA 1QUBA 4AYDA 1PPQA 4ONTD 2ERJA 2UWNA 2CG7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JRA A;  1HFI A;  2RLP A;  1E88 A;  1FBR A;  1ZJK A;  3L89 M;  4WJG 2;  2CKU A;  2JGX A;  1SRZ A;  2RKY A;  1QO6 A;  2LOJ A;  2XWB F;  1GKN A;  4J38 B;  1E5G A;  2JGW A;  2XWJ I;  4AYE A;  1OK1 A;  3GOV A;  3OP8 A;  4KKD A;  3M7P A;  4JHS A;  3O8E B;  1QGB A;  1GPZ A;  2RL0 A;  1H2Q P;  5HZP B;  1H03 P;  4C16 A;  2BZM A;  2V8E A;  1OK3 A;  3ZD2 A;  2EC3 A;  1C1Z A;  2A55 A;  3T5O A;  4FXG G;  4MUC A;  3ERB A;  5JPM G;  2XRD A;  2RKZ A;  5FO8 C;  1U5M A;  1GKG A;  4F4O C;  3OXU D;  1OJY A;  1TPM A;  2KRI A;  1MD8 A;  1OJV A;  2W81 A;  2XQW C;  2KMS A;  1VVC A;  2EHF A;  2MCZ A;  4LOS A;  5HYU B;  1O9A A;  1SS2 A;  1CKL A;  3KXV A;  2IZ4 A;  4AYM A;  1HFH A;  4B2S A;  2QY0 A;  5I0Q B;  4A5W B;  4IGD A;  4K12 A;  1Q3X A;  5HYP A;  3R62 A;  1MD7 A;  4YNX A;  2YRA A;  3IU3 I;  3CAL A;  3TVJ A;  1OK9 A;  3ZRZ A;  4B2R A;  4ZH1 D;  2CG6 A;  2G7I A;  1TPN A;  1G4F A;  4CSY A;  1VVD A;  2B5I D;  1Z92 B;  1H04 P;  3IX0 A;  4LOT A;  2MCY A;  1OJW A;  2IZ3 A;  3SW0 X;  4AYI A;  1HCC A;  4DJZ A;  2W80 A;  3OED C;  3EJH A;  1GHQ B;  1E8B A;  1TPG A;  3MQL A;  5HYT B;  1H2P P;  3RJ3 D;  1LY2 A;  3KZJ A;  1ELV A;  2YBY A;  3NFP I;  1NWV A;  1OK2 A;  2RLQ A;  1G4G A;  1UOT P;  2WII C;  3ZD1 A;  2O39 C;  4PZ5 A;  3INB C;  2XRB A;  3GXE A;  1QUB A;  4AYD A;  1PPQ A;  4ONT D;  2ERJ A;  2UWN A;  2CG7 A; 
#chains in the Genus database with same CATH topology
 2JRA A;  1HFI A;  2RLP A;  1E88 A;  3F6K A;  1FBR A;  1ZJK A;  3L89 M;  4WJG 2;  3ZLD A;  2CKU A;  3K3T A;  2JGX A;  1SRZ A;  3FGR A;  2ZYC A;  2RKY A;  1QO6 A;  2LOJ A;  2XWB F;  1GKN A;  4J38 B;  1E5G A;  4YIZ A;  2JGW A;  2XWJ I;  4AYE A;  1OK1 A;  3GOV A;  3OP8 A;  2Y8R A;  4KKD A;  3M7P A;  4JHS A;  3O8E B;  1QGB A;  1GPZ A;  2I2L A;  2RL0 A;  1H2Q P;  5HZP B;  1H03 P;  4C16 A;  2BZM A;  2V8E A;  1OK3 A;  3ZD2 A;  2X2Z A;  2EC3 A;  1C1Z A;  2A55 A;  3CI0 J;  3T5O A;  4APL A;  4FXG G;  3FGT A;  3ERB A;  4MUC A;  5JPM G;  2XRD A;  3WSY A;  3ZLE A;  2RKZ A;  5FO8 C;  1U5M A;  1GKG A;  4F4O C;  3OXU D;  1OJY A;  1TPM A;  2KRI A;  1MD8 A;  1OJV A;  2W81 A;  1RLH A;  2XQW C;  2KMS A;  1VVC A;  2EHF A;  2MCZ A;  4LOS A;  5HYU B;  1O9A A;  5DN5 A;  1SS2 A;  1CKL A;  3KXV A;  2IZ4 A;  4AYM A;  1HFH A;  4B2S A;  2QY0 A;  5I0Q B;  4A5W B;  4IGD A;  4K12 A;  1Q3X A;  5HYP A;  3R62 A;  1MD7 A;  4YNX A;  2YRA A;  3IU3 I;  5DN4 A;  3CAL A;  3TVJ A;  1OK9 A;  3ZRZ A;  4B2R A;  4ZH1 D;  2CG6 A;  2G7I A;  1TPN A;  4N7E A;  1G4F A;  4CSY A;  1VVD A;  2B5I D;  1Z92 B;  1H04 P;  3WSX A;  3IX0 A;  4LOT A;  2MCY A;  1OJW A;  2IZ3 A;  3SW0 X;  4AYI A;  3VWO A;  1HCC A;  4DJZ A;  2W80 A;  3OED C;  3EJH A;  1GHQ B;  3NJA A;  1E8B A;  1TPG A;  3MQL A;  5HYT B;  1H2P P;  3RJ3 D;  1LY2 A;  3KZJ A;  1ELV A;  2YBY A;  3NFP I;  1NWV A;  1OK2 A;  2RLQ A;  1G4G A;  1UOT P;  2WII C;  3ZD1 A;  2O39 C;  4MSL A;  4PZ5 A;  2Y8T A;  3INB C;  4BWC A;  2XRB A;  3GXE A;  4PO7 A;  1QUB A;  2Y8S A;  4AYD A;  1PPQ A;  4ONT D;  2ERJ A;  2UWN A;  2CG7 A; 
#chains in the Genus database with same CATH homology
 2JRA A;  1HFI A;  2RLP A;  1E88 A;  1FBR A;  1ZJK A;  3L89 M;  4WJG 2;  2CKU A;  2JGX A;  1SRZ A;  2RKY A;  1QO6 A;  2LOJ A;  2XWB F;  1GKN A;  4J38 B;  1E5G A;  2JGW A;  2XWJ I;  4AYE A;  1OK1 A;  3GOV A;  3OP8 A;  4KKD A;  3M7P A;  4JHS A;  3O8E B;  1QGB A;  1GPZ A;  2RL0 A;  1H2Q P;  5HZP B;  1H03 P;  4C16 A;  2BZM A;  2V8E A;  1OK3 A;  3ZD2 A;  2EC3 A;  1C1Z A;  2A55 A;  3T5O A;  4FXG G;  4MUC A;  3ERB A;  5JPM G;  2XRD A;  2RKZ A;  5FO8 C;  1U5M A;  1GKG A;  4F4O C;  3OXU D;  1OJY A;  1TPM A;  2KRI A;  1MD8 A;  1OJV A;  2W81 A;  2XQW C;  2KMS A;  1VVC A;  2EHF A;  2MCZ A;  4LOS A;  5HYU B;  1O9A A;  1SS2 A;  1CKL A;  3KXV A;  2IZ4 A;  4AYM A;  1HFH A;  4B2S A;  2QY0 A;  5I0Q B;  4A5W B;  4IGD A;  4K12 A;  1Q3X A;  5HYP A;  3R62 A;  1MD7 A;  4YNX A;  2YRA A;  3IU3 I;  3CAL A;  3TVJ A;  1OK9 A;  3ZRZ A;  4B2R A;  4ZH1 D;  2CG6 A;  2G7I A;  1TPN A;  1G4F A;  4CSY A;  1VVD A;  2B5I D;  1Z92 B;  1H04 P;  3IX0 A;  4LOT A;  2MCY A;  1OJW A;  2IZ3 A;  3SW0 X;  4AYI A;  1HCC A;  4DJZ A;  2W80 A;  3OED C;  3EJH A;  1GHQ B;  1E8B A;  1TPG A;  3MQL A;  5HYT B;  1H2P P;  3RJ3 D;  1LY2 A;  3KZJ A;  1ELV A;  2YBY A;  3NFP I;  1NWV A;  1OK2 A;  2RLQ A;  1G4G A;  1UOT P;  2WII C;  3ZD1 A;  2O39 C;  4PZ5 A;  3INB C;  2XRB A;  3GXE A;  1QUB A;  4AYD A;  1PPQ A;  4ONT D;  2ERJ A;  2UWN A;  2CG7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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