3SYVA

Crystal structure of mpacsin 3 f-bar domain mutant
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
285
structure length
249
Chain Sequence
SFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGAVEKGPQYGTLEKAWHAFFTAAERLSELHLEVREKLHGPDSERVRTWQRGAFHRQVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHTARKDEKEAEKMKTQYEQTLAELNRYTPRYMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQQSIEAASDEEDLRWWRSTHGPGMAQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords Protein kinase C and casein kinase II substrate protein 3
total genus 106
structure length 249
sequence length 285
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2011-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3syvA01
2RAIA 3HAJA 1I49A 4FZSA 2X3WA 3ABHA 3DYTA 3SOGA 3CAZA 4NSWA 4AVMA 2RAKA 2Z0OA 3Q0KA 2YKTA 1URUA 2D4CA 2X3VA 4WPCA 4DYLA 2Z0NA 1I4DA 3QNIA 3I2WA 3HAHA 3G9GA 2EFKA 1X04A 2D1LA 4AKVA 3OK8A 2FICA 4BNEA 3QE6A 3M3WA 4H8SA 3SYVA 2V0OA 1I4LA 2Q13A 2RAJA 1X03A 4WPEA 4ATMA 2EFLA 1Y2OA 1WDZA 3QWEA 4I1QA 5C5BB 2X3XA 3LLLA 5C5BA 3HAIA 3PLTA 1ZWWA 2ELBA 3ACOA 4DCNC 1I4TA 3Q84A 2Z0VA 4NQIA 2C08A 2Q12A
chains in the Genus database with same CATH superfamily
2Z0OA 4JL9A 2X3VA 2X5CA 5FLEX 4HR1B 1YWMA 1UPXA 1SU7A 3EJRA 3Q84A 3RV1A 3C7NA 3CV5A 3CZNA 4FZSA 3VEAA 2WINM 3BUPA 4B9QA 2Z0NA 3EJPA 1O7DB 2JNKA 4M0MA 4AZ7A 1SU6A 2D1LA 4HYBA 3OK8A 1TQSA 2WYHA 3O3NB 4EZXA 3D4YA 4EZTA 4DCNC 3DX4A 1TQUA 4AKVA 2MI7A 5FIGA 4UDYX 3OWGA 2GF4A 3A98A 4EZSA 1X04A 4IM3A 4EZZA 4BNEA 4JWIA 4AZBA 3O3MB 3QWEA 1HXKA 4G6QA 3L3OM 3DDGA 3LVTA 3ER8C 2ND0A 4D8JA 1ZWWA 1GN9A 4JWCA 4E81A 1R33A 4FZPA 4IWPA 3DDFA 4H8SA 4WPEA 1E9VA 3DPQA 3D2EA 1OAOA 1TQTA 4AZ5A 1E2UA 3I01A 2RAKA 2YKTA 3BVXA 5KBPA 3BVVA 2F18A 3D4ZA 4AZHA 3DX3A 4EZOA 3EJTA 3QA8A 4JWEA 3D52A 4JNEA 4UDXX 3O3OB 2WYIA 4EZRA 2Q12A 3KDRA 4IWOA 2YIBA 3BUBA 2GAFD 4DYLA 3T48A 3B52X 4EZPA 4R5KA 2Q13A 2YL9A 3T4AG 4I1QA 2OO2A 3VEBA 1I49A 3F7WA 3BUDA 2RT6A 2YL5A 3M3WA 2V0OA 3DPPA 4IM2A 4EZUA 3D50A 3VKHA 1I4TA 4NQIA 2NCZA 3HAJA 4AVMA 3ER9B 4AZIA 1GNLA 2YLLA 4NPHA 2FICA 2PMRA 3ERCC 2EFLA 3B51X 3ACOA 2QXLA 4R5JA 3KAVA 4AZCA 3ZEDA 4EZYA 3I04A 3CVRA 2ALWA 4KIKA 3BUQA 2F7RA 3DX0A 2Z8YA 3FD9A 2F7PA 3CKDA 4FM3A 2ZXQA 3EJQA 3KAWA 3BVWA 3DX1A 1R34A 2LXYA 5TKYA 3EJUA 2F7OA 4R5GA 3DX2A 4IW0A 3L3PA 1MJGA 1I4LA 4ATMA 1DKXA 2YI9A 4EZWA 4EZQA 3HAIA 3PLTA 4EZVA 3CZSA 2ELBA 2QKWA 4R5IA 1R5EA 4AZCB 4JN4A 4E3CA 1I4DA 4KIKB 3G9GA 1SU8A 2RAJA 4EZNA 2OW6A 4JNFA 4JLCA 5E84A 3D2FA 5C5BA 3B53X 3BLBA 3ABHA 4PO2A 2F1AA 3T49A 3Q0KA 3BVUA 2JNSA 2OZNB 3T47A 1SUFA 4R5LA 1X03A 1GNTA 3OHXM 4JWDA 2O0I1 2Z0VA 3GI7A 3RV0A 2QFFA 4H6HA 2OBMA 3DYTA 3SOGA 2YIAA 3QNJA 2EX3B 2PY6A 1TQWA 3QNIA 2YI8A 4AZ6A 1HTYA 2EWFA 1DKYA 1QWNA 2N3KA 2YL8A 5C5BB 1WDZA 2F7QA 3LLLA 3BVTA 2RAIA 1O7DC 2LM0A 4H6IA 2X3WA 3UITA 2D4CA 4WPCA 3I2WA 2EFKA 2YLAA 2GA9D 3I39X 1E1DA 3EJSA 1QWUA 1Y2OA 1DKZA 2X3XA 1LQ7A 2C08A 1TQVA 2YL6A 1HWWA 1OA1A 4IM0A 2KHOA 1URUA 2YIVX 2F1BA 2FYVA 4IWQA 4F01A 1ZYLA 4HR1A 3QE6A 3SYVA 3D51A 2OW7A 1U00A 4AZGA 3RPMA 1QX1A 1OA0A 3CAZA 4NSWA 3T46A 3HAHA 4HY9A 3LMFA 3DPOA 2ND1A 1JQKA 4FZOA 4F00A 3BUIA 1PS3A 1W9MA 2OBLA
chains in the Genus database with same CATH topology
2RAIA 3HAJA 1I49A 4FZSA 2X3WA 3ABHA 3DYTA 3SOGA 3CAZA 4NSWA 4AVMA 2RAKA 2Z0OA 3Q0KA 2YKTA 1URUA 2D4CA 2X3VA 4WPCA 4DYLA 2Z0NA 1I4DA 3QNIA 3I2WA 3HAHA 3G9GA 2EFKA 1X04A 2D1LA 4AKVA 3OK8A 2FICA 4BNEA 3QE6A 3M3WA 4H8SA 3SYVA 2V0OA 1I4LA 2Q13A 2RAJA 1X03A 4WPEA 4ATMA 2EFLA 1Y2OA 1WDZA 3QWEA 4I1QA 5C5BB 2X3XA 3LLLA 5C5BA 3HAIA 3PLTA 1ZWWA 2ELBA 3ACOA 4DCNC 1I4TA 3Q84A 2Z0VA 4NQIA 2C08A 2Q12A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RAI A;  3HAJ A;  1I49 A;  4FZS A;  2X3W A;  3ABH A;  3DYT A;  3SOG A;  3CAZ A;  4NSW A;  4AVM A;  2RAK A;  2Z0O A;  3Q0K A;  2YKT A;  1URU A;  2D4C A;  2X3V A;  4WPC A;  4DYL A;  2Z0N A;  1I4D A;  3QNI A;  3I2W A;  3HAH A;  3G9G A;  2EFK A;  1X04 A;  2D1L A;  4AKV A;  3OK8 A;  2FIC A;  4BNE A;  3QE6 A;  3M3W A;  4H8S A;  3SYV A;  2V0O A;  1I4L A;  2Q13 A;  2RAJ A;  1X03 A;  4WPE A;  4ATM A;  2EFL A;  1Y2O A;  1WDZ A;  3QWE A;  4I1Q A;  5C5B B;  2X3X A;  3LLL A;  5C5B A;  3HAI A;  3PLT A;  1ZWW A;  2ELB A;  3ACO A;  4DCN C;  1I4T A;  3Q84 A;  2Z0V A;  4NQI A;  2C08 A;  2Q12 A; 
#chains in the Genus database with same CATH topology
 2Z0O A;  4JL9 A;  2X3V A;  2X5C A;  5FLE X;  4HR1 B;  1YWM A;  1UPX A;  1SU7 A;  3EJR A;  3Q84 A;  3RV1 A;  3C7N A;  3CV5 A;  3CZN A;  4FZS A;  3VEA A;  2WIN M;  3BUP A;  4B9Q A;  2Z0N A;  3EJP A;  1O7D B;  2JNK A;  4M0M A;  4AZ7 A;  1SU6 A;  2D1L A;  4HYB A;  3OK8 A;  1TQS A;  2WYH A;  3O3N B;  4EZX A;  3D4Y A;  4EZT A;  4DCN C;  3DX4 A;  1TQU A;  4AKV A;  2MI7 A;  5FIG A;  4UDY X;  3OWG A;  2GF4 A;  3A98 A;  4EZS A;  1X04 A;  4IM3 A;  4EZZ A;  4BNE A;  4JWI A;  4AZB A;  3O3M B;  3QWE A;  1HXK A;  4G6Q A;  3L3O M;  3DDG A;  3LVT A;  3ER8 C;  2ND0 A;  4D8J A;  1ZWW A;  1GN9 A;  4JWC A;  4E81 A;  1R33 A;  4FZP A;  4IWP A;  3DDF A;  4H8S A;  4WPE A;  1E9V A;  3DPQ A;  3D2E A;  1OAO A;  1TQT A;  4AZ5 A;  1E2U A;  3I01 A;  2RAK A;  2YKT A;  3BVX A;  5KBP A;  3BVV A;  2F18 A;  3D4Z A;  4AZH A;  3DX3 A;  4EZO A;  3EJT A;  3QA8 A;  4JWE A;  3D52 A;  4JNE A;  4UDX X;  3O3O B;  2WYI A;  4EZR A;  2Q12 A;  3KDR A;  4IWO A;  2YIB A;  3BUB A;  2GAF D;  4DYL A;  3T48 A;  3B52 X;  4EZP A;  4R5K A;  2Q13 A;  2YL9 A;  3T4A G;  4I1Q A;  2OO2 A;  3VEB A;  1I49 A;  3F7W A;  3BUD A;  2RT6 A;  2YL5 A;  3M3W A;  2V0O A;  3DPP A;  4IM2 A;  4EZU A;  3D50 A;  3VKH A;  1I4T A;  4NQI A;  2NCZ A;  3HAJ A;  4AVM A;  3ER9 B;  4AZI A;  1GNL A;  2YLL A;  4NPH A;  2FIC A;  2PMR A;  3ERC C;  2EFL A;  3B51 X;  3ACO A;  2QXL A;  4R5J A;  3KAV A;  4AZC A;  3ZED A;  4EZY A;  3I04 A;  3CVR A;  2ALW A;  4KIK A;  3BUQ A;  2F7R A;  3DX0 A;  2Z8Y A;  3FD9 A;  2F7P A;  3CKD A;  4FM3 A;  2ZXQ A;  3EJQ A;  3KAW A;  3BVW A;  3DX1 A;  1R34 A;  2LXY A;  5TKY A;  3EJU A;  2F7O A;  4R5G A;  3DX2 A;  4IW0 A;  3L3P A;  1MJG A;  1I4L A;  4ATM A;  1DKX A;  2YI9 A;  4EZW A;  4EZQ A;  3HAI A;  3PLT A;  4EZV A;  3CZS A;  2ELB A;  2QKW A;  4R5I A;  1R5E A;  4AZC B;  4JN4 A;  4E3C A;  1I4D A;  4KIK B;  3G9G A;  1SU8 A;  2RAJ A;  4EZN A;  2OW6 A;  4JNF A;  4JLC A;  5E84 A;  3D2F A;  5C5B A;  3B53 X;  3BLB A;  3ABH A;  4PO2 A;  2F1A A;  3T49 A;  3Q0K A;  3BVU A;  2JNS A;  2OZN B;  3T47 A;  1SUF A;  4R5L A;  1X03 A;  1GNT A;  3OHX M;  4JWD A;  2O0I 1;  2Z0V A;  3GI7 A;  3RV0 A;  2QFF A;  4H6H A;  2OBM A;  3DYT A;  3SOG A;  2YIA A;  3QNJ A;  2EX3 B;  2PY6 A;  1TQW A;  3QNI A;  2YI8 A;  4AZ6 A;  1HTY A;  2EWF A;  1DKY A;  1QWN A;  2N3K A;  2YL8 A;  5C5B B;  1WDZ A;  2F7Q A;  3LLL A;  3BVT A;  2RAI A;  1O7D C;  2LM0 A;  4H6I A;  2X3W A;  3UIT A;  2D4C A;  4WPC A;  3I2W A;  2EFK A;  2YLA A;  2GA9 D;  3I39 X;  1E1D A;  3EJS A;  1QWU A;  1Y2O A;  1DKZ A;  2X3X A;  1LQ7 A;  2C08 A;  1TQV A;  2YL6 A;  1HWW A;  1OA1 A;  4IM0 A;  2KHO A;  1URU A;  2YIV X;  2F1B A;  2FYV A;  4IWQ A;  4F01 A;  1ZYL A;  4HR1 A;  3QE6 A;  3SYV A;  3D51 A;  2OW7 A;  1U00 A;  4AZG A;  3RPM A;  1QX1 A;  1OA0 A;  3CAZ A;  4NSW A;  3T46 A;  3HAH A;  4HY9 A;  3LMF A;  3DPO A;  2ND1 A;  1JQK A;  4FZO A;  4F00 A;  3BUI A;  1PS3 A;  1W9M A;  2OBL A; 
#chains in the Genus database with same CATH homology
 2RAI A;  3HAJ A;  1I49 A;  4FZS A;  2X3W A;  3ABH A;  3DYT A;  3SOG A;  3CAZ A;  4NSW A;  4AVM A;  2RAK A;  2Z0O A;  3Q0K A;  2YKT A;  1URU A;  2D4C A;  2X3V A;  4WPC A;  4DYL A;  2Z0N A;  1I4D A;  3QNI A;  3I2W A;  3HAH A;  3G9G A;  2EFK A;  1X04 A;  2D1L A;  4AKV A;  3OK8 A;  2FIC A;  4BNE A;  3QE6 A;  3M3W A;  4H8S A;  3SYV A;  2V0O A;  1I4L A;  2Q13 A;  2RAJ A;  1X03 A;  4WPE A;  4ATM A;  2EFL A;  1Y2O A;  1WDZ A;  3QWE A;  4I1Q A;  5C5B B;  2X3X A;  3LLL A;  5C5B A;  3HAI A;  3PLT A;  1ZWW A;  2ELB A;  3ACO A;  4DCN C;  1I4T A;  3Q84 A;  2Z0V A;  4NQI A;  2C08 A;  2Q12 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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