3T3JA

1.70 a structure of friedreich's ataxia frataxin variant n146k
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
123
structure length
123
Chain Sequence
HPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVIKKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Frataxin, mitochondrial
publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
source organism Homo sapiens
total genus 36
structure length 123
sequence length 123
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3jA00
3OERA 2FQLA 3S5DA 1EW4A 3T3JA 3T3LA 1EKGA 3T3TA 3S5EA 3OEQA 4JPDA 4EC2A 1SOYA 3T3KA 3S4MA 4LP1A 4HS5A 2P1XA 1LY7A 3S5FA 3T3XA 4LK8A 2EFFA 2GA5A
chains in the Genus database with same CATH superfamily
3OERA 2FQLA 3S5DA 1EW4A 3T3JA 3SSEA 3IAM7 1D2MA 2FUG7 3T3LA 1EKGA 3A5PA 3IMOA 3T3TA 4HEA7 3OEQA 3S5EA 4JPDA 4C26A 4EC2A 1SOYA 1V5RA 3GD0A 3SSDA 4P78C 3T3KA 3S4MA 3GD9A 3SSCA 4LP1A 3IAS7 4HS5A 1WHZA 2P1XA 1LY7A 3S5FA 3T3XA 3I9V7 4LK8A 2EFFA 2GA5A
chains in the Genus database with same CATH topology
3OERA 2FQLA 3S5DA 1EW4A 3T3JA 3T3LA 1EKGA 3T3TA 3S5EA 3OEQA 4JPDA 4EC2A 1SOYA 3T3KA 3S4MA 4LP1A 4HS5A 2P1XA 1LY7A 3S5FA 3T3XA 4LK8A 2EFFA 2GA5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OER A;  2FQL A;  3S5D A;  1EW4 A;  3T3J A;  3T3L A;  1EKG A;  3T3T A;  3S5E A;  3OEQ A;  4JPD A;  4EC2 A;  1SOY A;  3T3K A;  3S4M A;  4LP1 A;  4HS5 A;  2P1X A;  1LY7 A;  3S5F A;  3T3X A;  4LK8 A;  2EFF A;  2GA5 A; 
#chains in the Genus database with same CATH topology
 3OER A;  2FQL A;  3S5D A;  1EW4 A;  3T3J A;  3SSE A;  3IAM 7;  1D2M A;  2FUG 7;  3T3L A;  1EKG A;  3A5P A;  3IMO A;  3T3T A;  4HEA 7;  3OEQ A;  3S5E A;  4JPD A;  4C26 A;  4EC2 A;  1SOY A;  1V5R A;  3GD0 A;  3SSD A;  4P78 C;  3T3K A;  3S4M A;  3GD9 A;  3SSC A;  4LP1 A;  3IAS 7;  4HS5 A;  1WHZ A;  2P1X A;  1LY7 A;  3S5F A;  3T3X A;  3I9V 7;  4LK8 A;  2EFF A;  2GA5 A; 
#chains in the Genus database with same CATH homology
 3OER A;  2FQL A;  3S5D A;  1EW4 A;  3T3J A;  3T3L A;  1EKG A;  3T3T A;  3S5E A;  3OEQ A;  4JPD A;  4EC2 A;  1SOY A;  3T3K A;  3S4M A;  4LP1 A;  4HS5 A;  2P1X A;  1LY7 A;  3S5F A;  3T3X A;  4LK8 A;  2EFF A;  2GA5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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