3T3KA

1.24 a structure of friedreich's ataxia frataxin variant q148r
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
122
structure length
122
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKRTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Frataxin, mitochondrial
publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
source organism Homo sapiens
total genus 34
structure length 122
sequence length 122
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3kA00
4HS5A 4LP1A 2FQLA 3T3KA 4JPDA 3S5EA 1SOYA 2P1XA 3T3JA 3OERA 3T3LA 3T3TA 1EKGA 3S4MA 4LK8A 3T3XA 3S5DA 2GA5A 1LY7A 3S5FA 2EFFA 3OEQA 1EW4A 4EC2A
chains in the Genus database with same CATH superfamily
1D2MA 4HS5A 4LP1A 3A5PA 2FQLA 3T3KA 1WHZA 4JPDA 3S5EA 1SOYA 3GD0A 3I9V7 2P1XA 3T3JA 3OERA 1V5RA 3SSDA 3SSCA 2FUG7 3T3LA 3GD9A 1EKGA 3S4MA 4HEA7 4LK8A 4P78C 3T3TA 4C26A 3T3XA 3IMOA 3IAS7 3S5DA 2GA5A 1LY7A 3SSEA 3S5FA 2EFFA 3IAM7 3OEQA 1EW4A 4EC2A
chains in the Genus database with same CATH topology
4HS5A 4LP1A 2FQLA 3T3KA 4JPDA 3S5EA 1SOYA 2P1XA 3T3JA 3OERA 3T3LA 3T3TA 1EKGA 3S4MA 4LK8A 3T3XA 3S5DA 2GA5A 1LY7A 3S5FA 2EFFA 3OEQA 1EW4A 4EC2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HS5 A;  4LP1 A;  2FQL A;  3T3K A;  4JPD A;  3S5E A;  1SOY A;  2P1X A;  3T3J A;  3OER A;  3T3L A;  3T3T A;  1EKG A;  3S4M A;  4LK8 A;  3T3X A;  3S5D A;  2GA5 A;  1LY7 A;  3S5F A;  2EFF A;  3OEQ A;  1EW4 A;  4EC2 A; 
#chains in the Genus database with same CATH topology
 1D2M A;  4HS5 A;  4LP1 A;  3A5P A;  2FQL A;  3T3K A;  1WHZ A;  4JPD A;  3S5E A;  1SOY A;  3GD0 A;  3I9V 7;  2P1X A;  3T3J A;  3OER A;  1V5R A;  3SSD A;  3SSC A;  2FUG 7;  3T3L A;  3GD9 A;  1EKG A;  3S4M A;  4HEA 7;  4LK8 A;  4P78 C;  3T3T A;  4C26 A;  3T3X A;  3IMO A;  3IAS 7;  3S5D A;  2GA5 A;  1LY7 A;  3SSE A;  3S5F A;  2EFF A;  3IAM 7;  3OEQ A;  1EW4 A;  4EC2 A; 
#chains in the Genus database with same CATH homology
 4HS5 A;  4LP1 A;  2FQL A;  3T3K A;  4JPD A;  3S5E A;  1SOY A;  2P1X A;  3T3J A;  3OER A;  3T3L A;  3T3T A;  1EKG A;  3S4M A;  4LK8 A;  3T3X A;  3S5D A;  2GA5 A;  1LY7 A;  3S5F A;  2EFF A;  3OEQ A;  1EW4 A;  4EC2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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