3T3TA

1.38 a structure of human frataxin variant q148g
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
120
structure length
120
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKGTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Frataxin, mitochondrial
publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
source organism Homo sapiens
total genus 36
structure length 120
sequence length 120
chains with identical sequence B, C, D
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3tA00
1EW4A 3S5FA 4LK8A 3OERA 1LY7A 4JPDA 3T3KA 3S5EA 3T3LA 3T3TA 2P1XA 2EFFA 4HS5A 4EC2A 3S5DA 4LP1A 2GA5A 3T3XA 3OEQA 3S4MA 1EKGA 2FQLA 3T3JA 1SOYA
chains in the Genus database with same CATH superfamily
4P78C 1EW4A 3A5PA 3S5FA 3SSEA 4LK8A 3GD0A 3IAM7 3IMOA 3OERA 4HEA7 1LY7A 4JPDA 3T3KA 3S5EA 3T3LA 3SSCA 3T3TA 2FUG7 3GD9A 2P1XA 2EFFA 1V5RA 3SSDA 3I9V7 4HS5A 4EC2A 3S5DA 4LP1A 2GA5A 3T3XA 3OEQA 1WHZA 4C26A 3S4MA 1EKGA 3IAS7 1D2MA 2FQLA 3T3JA 1SOYA
chains in the Genus database with same CATH topology
1EW4A 3S5FA 4LK8A 3OERA 1LY7A 4JPDA 3T3KA 3S5EA 3T3LA 3T3TA 2P1XA 2EFFA 4HS5A 4EC2A 3S5DA 4LP1A 2GA5A 3T3XA 3OEQA 3S4MA 1EKGA 2FQLA 3T3JA 1SOYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EW4 A;  3S5F A;  4LK8 A;  3OER A;  1LY7 A;  4JPD A;  3T3K A;  3S5E A;  3T3L A;  3T3T A;  2P1X A;  2EFF A;  4HS5 A;  4EC2 A;  3S5D A;  4LP1 A;  2GA5 A;  3T3X A;  3OEQ A;  3S4M A;  1EKG A;  2FQL A;  3T3J A;  1SOY A; 
#chains in the Genus database with same CATH topology
 4P78 C;  1EW4 A;  3A5P A;  3S5F A;  3SSE A;  4LK8 A;  3GD0 A;  3IAM 7;  3IMO A;  3OER A;  4HEA 7;  1LY7 A;  4JPD A;  3T3K A;  3S5E A;  3T3L A;  3SSC A;  3T3T A;  2FUG 7;  3GD9 A;  2P1X A;  2EFF A;  1V5R A;  3SSD A;  3I9V 7;  4HS5 A;  4EC2 A;  3S5D A;  4LP1 A;  2GA5 A;  3T3X A;  3OEQ A;  1WHZ A;  4C26 A;  3S4M A;  1EKG A;  3IAS 7;  1D2M A;  2FQL A;  3T3J A;  1SOY A; 
#chains in the Genus database with same CATH homology
 1EW4 A;  3S5F A;  4LK8 A;  3OER A;  1LY7 A;  4JPD A;  3T3K A;  3S5E A;  3T3L A;  3T3T A;  2P1X A;  2EFF A;  4HS5 A;  4EC2 A;  3S5D A;  4LP1 A;  2GA5 A;  3T3X A;  3OEQ A;  3S4M A;  1EKG A;  2FQL A;  3T3J A;  1SOY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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