3T3XA

1.57 a structure of friedreich's ataxia frataxin variant r165c
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
122
structure length
122
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKCYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Frataxin, mitochondrial
publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
source organism Homo sapiens
total genus 35
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3xA00
2P1XA 1EKGA 4JPDA 3T3LA 3S4MA 4LP1A 1EW4A 2EFFA 2FQLA 1SOYA 3T3XA 3T3JA 3S5EA 3S5FA 4EC2A 3S5DA 3OEQA 4LK8A 3T3TA 2GA5A 3T3KA 1LY7A 4HS5A 3OERA
chains in the Genus database with same CATH superfamily
3IAS7 2P1XA 1D2MA 4P78C 1EKGA 3IAM7 3A5PA 4JPDA 3T3LA 3S4MA 4LP1A 1EW4A 2FQLA 1SOYA 4C26A 3T3XA 3T3JA 3GD9A 1WHZA 3S5EA 3GD0A 4HEA7 3S5FA 4EC2A 3SSEA 3IMOA 1V5RA 3S5DA 2FUG7 3SSDA 3OEQA 3I9V7 4LK8A 3T3TA 3SSCA 2GA5A 3T3KA 3OERA 1LY7A 4HS5A 2EFFA
chains in the Genus database with same CATH topology
2P1XA 1EKGA 4JPDA 3T3LA 3S4MA 4LP1A 1EW4A 2EFFA 2FQLA 1SOYA 3T3XA 3T3JA 3S5EA 3S5FA 4EC2A 3S5DA 3OEQA 4LK8A 3T3TA 2GA5A 3T3KA 1LY7A 4HS5A 3OERA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P1X A;  1EKG A;  4JPD A;  3T3L A;  3S4M A;  4LP1 A;  1EW4 A;  2EFF A;  2FQL A;  1SOY A;  3T3X A;  3T3J A;  3S5E A;  3S5F A;  4EC2 A;  3S5D A;  3OEQ A;  4LK8 A;  3T3T A;  2GA5 A;  3T3K A;  1LY7 A;  4HS5 A;  3OER A; 
#chains in the Genus database with same CATH topology
 3IAS 7;  2P1X A;  1D2M A;  4P78 C;  1EKG A;  3IAM 7;  3A5P A;  4JPD A;  3T3L A;  3S4M A;  4LP1 A;  1EW4 A;  2FQL A;  1SOY A;  4C26 A;  3T3X A;  3T3J A;  3GD9 A;  1WHZ A;  3S5E A;  3GD0 A;  4HEA 7;  3S5F A;  4EC2 A;  3SSE A;  3IMO A;  1V5R A;  3S5D A;  2FUG 7;  3SSD A;  3OEQ A;  3I9V 7;  4LK8 A;  3T3T A;  3SSC A;  2GA5 A;  3T3K A;  3OER A;  1LY7 A;  4HS5 A;  2EFF A; 
#chains in the Genus database with same CATH homology
 2P1X A;  1EKG A;  4JPD A;  3T3L A;  3S4M A;  4LP1 A;  1EW4 A;  2EFF A;  2FQL A;  1SOY A;  3T3X A;  3T3J A;  3S5E A;  3S5F A;  4EC2 A;  3S5D A;  3OEQ A;  4LK8 A;  3T3T A;  2GA5 A;  3T3K A;  1LY7 A;  4HS5 A;  3OER A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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