3T3XA

1.57 a structure of friedreich's ataxia frataxin variant r165c
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
122
structure length
122
Chain Sequence
SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKCYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
pubmed doi rcsb
molecule keywords Frataxin, mitochondrial
molecule tags Oxidoreductase
source organism Homo sapiens
total genus 35
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2011-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 3t3xA00
4JPDA 2EFFA 1EW4A 4HS5A 3T3LA 2P1XA 3T3KA 2FQLA 2GA5A 3S4MA 3T3TA 3T3JA 4EC2A 3T3XA 3OEQA 1SOYA 3OERA 3S5EA 3S5FA 4LP1A 4LK8A 1LY7A 3S5DA 1EKGA
chains in the Genus database with same CATH superfamily
4JPDA 4P78C 3IMOA 2EFFA 3A5PA 1WHZA 1EW4A 4HS5A 3T3LA 3SSDA 2P1XA 3T3KA 3IAM7 2FQLA 2GA5A 3S4MA 3T3TA 4C26A 1V5RA 3T3JA 4EC2A 3T3XA 2FUG7 3SSEA 3OEQA 1SOYA 3IAS7 3OERA 3S5EA 3I9V7 1D2MA 4HEA7 3S5FA 3GD0A 3SSCA 4LP1A 4LK8A 3GD9A 1LY7A 3S5DA 1EKGA
chains in the Genus database with same CATH topology
4JPDA 2EFFA 1EW4A 4HS5A 3T3LA 2P1XA 3T3KA 2FQLA 2GA5A 3S4MA 3T3TA 3T3JA 4EC2A 3T3XA 3OEQA 1SOYA 3OERA 3S5EA 3S5FA 4LP1A 4LK8A 1LY7A 3S5DA 1EKGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JPD A;  2EFF A;  1EW4 A;  4HS5 A;  3T3L A;  2P1X A;  3T3K A;  2FQL A;  2GA5 A;  3S4M A;  3T3T A;  3T3J A;  4EC2 A;  3T3X A;  3OEQ A;  1SOY A;  3OER A;  3S5E A;  3S5F A;  4LP1 A;  4LK8 A;  1LY7 A;  3S5D A;  1EKG A; 
#chains in the Genus database with same CATH topology
 4JPD A;  4P78 C;  3IMO A;  2EFF A;  3A5P A;  1WHZ A;  1EW4 A;  4HS5 A;  3T3L A;  3SSD A;  2P1X A;  3T3K A;  3IAM 7;  2FQL A;  2GA5 A;  3S4M A;  3T3T A;  4C26 A;  1V5R A;  3T3J A;  4EC2 A;  3T3X A;  2FUG 7;  3SSE A;  3OEQ A;  1SOY A;  3IAS 7;  3OER A;  3S5E A;  3I9V 7;  1D2M A;  4HEA 7;  3S5F A;  3GD0 A;  3SSC A;  4LP1 A;  4LK8 A;  3GD9 A;  1LY7 A;  3S5D A;  1EKG A; 
#chains in the Genus database with same CATH homology
 4JPD A;  2EFF A;  1EW4 A;  4HS5 A;  3T3L A;  2P1X A;  3T3K A;  2FQL A;  2GA5 A;  3S4M A;  3T3T A;  3T3J A;  4EC2 A;  3T3X A;  3OEQ A;  1SOY A;  3OER A;  3S5E A;  3S5F A;  4LP1 A;  4LK8 A;  1LY7 A;  3S5D A;  1EKG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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