3T62D

Crystal structure of recombinant kunitz type serine protease inhibitor-1 from the caribbean sea anemone stichodactyla helianthus in complex with bovine chymotrypsin
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
54
structure length
54
Chain Sequence
SICSEPKKVGRCKGYFPRFYFDSETGKCTPFIYGGCGGNGNNFETLHQCRAICR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Chymotrypsinogen A
publication title Structural insights into chymotrypsin inhibition by the Kunitz-type inhibitor-1 from the marine invertebrate Stichodactyla helianthus
rcsb
source organism Stichodactyla helianthus
total genus 7
structure length 54
sequence length 54
chains with identical sequence E, F
ec nomenclature
pdb deposition date 2011-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3t62D00
2FI3I 2LFLA 2ZVXA 1BZXI 4BD9B 1TOCR 2UUXA 1JV9A 3LDIA 4PTIA 3OFWA 1FY8I 2FI5I 3BTWI 1EJMB 1P2KI 2TGPI 3CI7A 3BTHI 2JOTA 3AUGA 2RA3C 3UOUB 1BRBI 1FANA 1F5RI 1T8NB 3TGJI 4Y0ZI 4Y10I 1T8MB 1YLDB 3U1JE 1PITA 1BZ5A 1ZR0B 5JB6A 2DDJA 1B0CA 3T62D 1KNTA 1YKTB 1BPTA 4DG4C 1KIGI 1OA65 1CO7I 4U32X 3AUHA 1YC0I 3BTKI 1F7ZI 8PTIA 2CA7A 2J6DA 3BTGI 3OTJI 2KCRA 1UUBA 1Y62A 3P92E 1BPIA 4U30W 1EAWB 1BUNB 1MTND 5C67C 1AAPA 1G6XA 1TAWB 4ISOB 3L33E 1CBWD 4NTYB 1P2OB 1T8LB 2FTLI 3AUEA 6PTIA 3FP6I 3BYBA 9PTIA 3GYMI 3BTTI 1BTIA 4TPII 5PTIA 3LDJA 4Y11I 2IJOI 4ISNB 3UIRC 2FTMB 1D0DB 2W8XA 1TFXC 1KUNA 1ADZA 1OA55 4Y0YI 1JC6A 1DTXA 1IRHA 2M99A 1P2JI 1P2MB 4BQDA 3AUDA 3L3TE 1BHCA 2FI4I 1DTKA 1D0DA 3D65I 1ZJDB 2HEXA 2LFKA 1AALA 1FAKI 1T8OB 1SHPA 3AUBA 3TGKI 1QLQA 3AUIA 3BTFI 3M7QB 3FP8I 3BTDI 1UUAA 1NAGA 3TGII 1DEMA 1BIKA 2KNTA 4NTWB 4WXVC 1JV8A 2ZJXA 1P2II 2PTCI 3AUCA 3P95E 2TPII 1BF0A 1LD5A 4BNRI 3WNYA 2M01A 1TCPA 5JB4A 1BRCI 1TAPA 1K6UA 3BTQI 5JB5A 1LD6A 4NTXB 3BTEI 1P2NB 5JB7A 3TPII 3LDMA 2DDIA 1KTHA 4WWYC 7PTIA 3FP7J 4DTGK 1CA0D 2R9PE 3BTMI 4ISLB 1BTHP 2KAII 1P2QB 2UUYB 1DENA 1TPAI 2ODYE 1YLCB 1T7CB
chains in the Genus database with same CATH superfamily
2FI3I 2LFLA 2ZVXA 1BZXI 4BD9B 1TOCR 2UUXA 1JV9A 3LDIA 4PTIA 3OFWA 1FY8I 2FI5I 3BTWI 1EJMB 1P2KI 2TGPI 3CI7A 3BTHI 2JOTA 3AUGA 2RA3C 3UOUB 1BRBI 1FANA 1F5RI 1T8NB 3TGJI 4Y0ZI 4Y10I 1T8MB 1YLDB 3U1JE 1PITA 1BZ5A 1ZR0B 5JB6A 2DDJA 1B0CA 3T62D 1KNTA 1YKTB 1BPTA 4DG4C 1KIGI 1OA65 1CO7I 4U32X 3AUHA 1YC0I 3BTKI 1F7ZI 8PTIA 2CA7A 2J6DA 3BTGI 3OTJI 2KCRA 1UUBA 1Y62A 3P92E 1BPIA 4U30W 1EAWB 1BUNB 1MTND 5C67C 1AAPA 1G6XA 1TAWB 4ISOB 3L33E 1CBWD 4NTYB 1P2OB 1T8LB 2FTLI 3AUEA 6PTIA 3FP6I 3BYBA 9PTIA 3GYMI 3BTTI 1BTIA 4TPII 5PTIA 3LDJA 4Y11I 2IJOI 4ISNB 3UIRC 2FTMB 1D0DB 2W8XA 1TFXC 1KUNA 1ADZA 1OA55 4Y0YI 1JC6A 1DTXA 1IRHA 2M99A 1P2JI 1P2MB 4BQDA 3AUDA 3L3TE 1BHCA 2FI4I 1DTKA 1D0DA 3D65I 1ZJDB 2HEXA 2LFKA 1AALA 1FAKI 1T8OB 1SHPA 3AUBA 3TGKI 1QLQA 3AUIA 3BTFI 3M7QB 3FP8I 3BTDI 1UUAA 1NAGA 3TGII 1DEMA 1BIKA 2KNTA 4NTWB 4WXVC 1JV8A 2ZJXA 1P2II 2PTCI 3AUCA 3P95E 2TPII 1BF0A 1LD5A 4BNRI 3WNYA 2M01A 1TCPA 5JB4A 1BRCI 1TAPA 1K6UA 3BTQI 5JB5A 1LD6A 4NTXB 3BTEI 1P2NB 5JB7A 3TPII 3LDMA 2DDIA 1KTHA 4WWYC 7PTIA 3FP7J 4DTGK 1CA0D 2R9PE 3BTMI 4ISLB 1BTHP 2KAII 1P2QB 2UUYB 1DENA 1TPAI 2ODYE 1YLCB 1T7CB
chains in the Genus database with same CATH topology
2FI3I 2LFLA 2ZVXA 1BZXI 4BD9B 1TOCR 2UUXA 1JV9A 3LDIA 4PTIA 3OFWA 1FY8I 2FI5I 3BTWI 1EJMB 1P2KI 2TGPI 3CI7A 3BTHI 2JOTA 3AUGA 2RA3C 3UOUB 1BRBI 1FANA 1F5RI 1T8NB 3TGJI 4Y0ZI 4Y10I 1T8MB 1YLDB 3U1JE 1PITA 1BZ5A 1ZR0B 5JB6A 2DDJA 1B0CA 3T62D 1KNTA 1YKTB 1BPTA 4DG4C 1KIGI 1OA65 1CO7I 4U32X 3AUHA 1YC0I 3BTKI 1F7ZI 8PTIA 2CA7A 2J6DA 3BTGI 3OTJI 2KCRA 1UUBA 1Y62A 3P92E 1BPIA 4U30W 1EAWB 1BUNB 1MTND 5C67C 1AAPA 1G6XA 1TAWB 4ISOB 3L33E 1CBWD 4NTYB 1P2OB 1T8LB 2FTLI 3AUEA 6PTIA 3FP6I 3BYBA 9PTIA 3GYMI 3BTTI 1BTIA 4TPII 5PTIA 3LDJA 4Y11I 2IJOI 4ISNB 3UIRC 2FTMB 1D0DB 2W8XA 1TFXC 1KUNA 1ADZA 1OA55 4Y0YI 1JC6A 1DTXA 1IRHA 2M99A 1P2JI 1P2MB 4BQDA 3AUDA 3L3TE 1BHCA 2FI4I 1DTKA 1D0DA 3D65I 1ZJDB 2HEXA 2LFKA 1AALA 1FAKI 1T8OB 1SHPA 3AUBA 3TGKI 1QLQA 3AUIA 3BTFI 3M7QB 3FP8I 3BTDI 1UUAA 1NAGA 3TGII 1DEMA 1BIKA 2KNTA 4NTWB 4WXVC 1JV8A 2ZJXA 1P2II 2PTCI 3AUCA 3P95E 2TPII 1BF0A 1LD5A 4BNRI 3WNYA 2M01A 1TCPA 5JB4A 1BRCI 1TAPA 1K6UA 3BTQI 5JB5A 1LD6A 4NTXB 3BTEI 1P2NB 5JB7A 3TPII 3LDMA 2DDIA 1KTHA 4WWYC 7PTIA 3FP7J 4DTGK 1CA0D 2R9PE 3BTMI 4ISLB 1BTHP 2KAII 1P2QB 2UUYB 1DENA 1TPAI 2ODYE 1YLCB 1T7CB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FI3 I;  2LFL A;  2ZVX A;  1BZX I;  4BD9 B;  1TOC R;  2UUX A;  1JV9 A;  3LDI A;  4PTI A;  3OFW A;  1FY8 I;  2FI5 I;  3BTW I;  1EJM B;  1P2K I;  2TGP I;  3CI7 A;  3BTH I;  2JOT A;  3AUG A;  2RA3 C;  3UOU B;  1BRB I;  1FAN A;  1F5R I;  1T8N B;  3TGJ I;  4Y0Z I;  4Y10 I;  1T8M B;  1YLD B;  3U1J E;  1PIT A;  1BZ5 A;  1ZR0 B;  5JB6 A;  2DDJ A;  1B0C A;  3T62 D;  1KNT A;  1YKT B;  1BPT A;  4DG4 C;  1KIG I;  1OA6 5;  1CO7 I;  4U32 X;  3AUH A;  1YC0 I;  3BTK I;  1F7Z I;  8PTI A;  2CA7 A;  2J6D A;  3BTG I;  3OTJ I;  2KCR A;  1UUB A;  1Y62 A;  3P92 E;  1BPI A;  4U30 W;  1EAW B;  1BUN B;  1MTN D;  5C67 C;  1AAP A;  1G6X A;  1TAW B;  4ISO B;  3L33 E;  1CBW D;  4NTY B;  1P2O B;  1T8L B;  2FTL I;  3AUE A;  6PTI A;  3FP6 I;  3BYB A;  9PTI A;  3GYM I;  3BTT I;  1BTI A;  4TPI I;  5PTI A;  3LDJ A;  4Y11 I;  2IJO I;  4ISN B;  3UIR C;  2FTM B;  1D0D B;  2W8X A;  1TFX C;  1KUN A;  1ADZ A;  1OA5 5;  4Y0Y I;  1JC6 A;  1DTX A;  1IRH A;  2M99 A;  1P2J I;  1P2M B;  4BQD A;  3AUD A;  3L3T E;  1BHC A;  2FI4 I;  1DTK A;  1D0D A;  3D65 I;  1ZJD B;  2HEX A;  2LFK A;  1AAL A;  1FAK I;  1T8O B;  1SHP A;  3AUB A;  3TGK I;  1QLQ A;  3AUI A;  3BTF I;  3M7Q B;  3FP8 I;  3BTD I;  1UUA A;  1NAG A;  3TGI I;  1DEM A;  1BIK A;  2KNT A;  4NTW B;  4WXV C;  1JV8 A;  2ZJX A;  1P2I I;  2PTC I;  3AUC A;  3P95 E;  2TPI I;  1BF0 A;  1LD5 A;  4BNR I;  3WNY A;  2M01 A;  1TCP A;  5JB4 A;  1BRC I;  1TAP A;  1K6U A;  3BTQ I;  5JB5 A;  1LD6 A;  4NTX B;  3BTE I;  1P2N B;  5JB7 A;  3TPI I;  3LDM A;  2DDI A;  1KTH A;  4WWY C;  7PTI A;  3FP7 J;  4DTG K;  1CA0 D;  2R9P E;  3BTM I;  4ISL B;  1BTH P;  2KAI I;  1P2Q B;  2UUY B;  1DEN A;  1TPA I;  2ODY E;  1YLC B;  1T7C B; 
#chains in the Genus database with same CATH topology
 2FI3 I;  2LFL A;  2ZVX A;  1BZX I;  4BD9 B;  1TOC R;  2UUX A;  1JV9 A;  3LDI A;  4PTI A;  3OFW A;  1FY8 I;  2FI5 I;  3BTW I;  1EJM B;  1P2K I;  2TGP I;  3CI7 A;  3BTH I;  2JOT A;  3AUG A;  2RA3 C;  3UOU B;  1BRB I;  1FAN A;  1F5R I;  1T8N B;  3TGJ I;  4Y0Z I;  4Y10 I;  1T8M B;  1YLD B;  3U1J E;  1PIT A;  1BZ5 A;  1ZR0 B;  5JB6 A;  2DDJ A;  1B0C A;  3T62 D;  1KNT A;  1YKT B;  1BPT A;  4DG4 C;  1KIG I;  1OA6 5;  1CO7 I;  4U32 X;  3AUH A;  1YC0 I;  3BTK I;  1F7Z I;  8PTI A;  2CA7 A;  2J6D A;  3BTG I;  3OTJ I;  2KCR A;  1UUB A;  1Y62 A;  3P92 E;  1BPI A;  4U30 W;  1EAW B;  1BUN B;  1MTN D;  5C67 C;  1AAP A;  1G6X A;  1TAW B;  4ISO B;  3L33 E;  1CBW D;  4NTY B;  1P2O B;  1T8L B;  2FTL I;  3AUE A;  6PTI A;  3FP6 I;  3BYB A;  9PTI A;  3GYM I;  3BTT I;  1BTI A;  4TPI I;  5PTI A;  3LDJ A;  4Y11 I;  2IJO I;  4ISN B;  3UIR C;  2FTM B;  1D0D B;  2W8X A;  1TFX C;  1KUN A;  1ADZ A;  1OA5 5;  4Y0Y I;  1JC6 A;  1DTX A;  1IRH A;  2M99 A;  1P2J I;  1P2M B;  4BQD A;  3AUD A;  3L3T E;  1BHC A;  2FI4 I;  1DTK A;  1D0D A;  3D65 I;  1ZJD B;  2HEX A;  2LFK A;  1AAL A;  1FAK I;  1T8O B;  1SHP A;  3AUB A;  3TGK I;  1QLQ A;  3AUI A;  3BTF I;  3M7Q B;  3FP8 I;  3BTD I;  1UUA A;  1NAG A;  3TGI I;  1DEM A;  1BIK A;  2KNT A;  4NTW B;  4WXV C;  1JV8 A;  2ZJX A;  1P2I I;  2PTC I;  3AUC A;  3P95 E;  2TPI I;  1BF0 A;  1LD5 A;  4BNR I;  3WNY A;  2M01 A;  1TCP A;  5JB4 A;  1BRC I;  1TAP A;  1K6U A;  3BTQ I;  5JB5 A;  1LD6 A;  4NTX B;  3BTE I;  1P2N B;  5JB7 A;  3TPI I;  3LDM A;  2DDI A;  1KTH A;  4WWY C;  7PTI A;  3FP7 J;  4DTG K;  1CA0 D;  2R9P E;  3BTM I;  4ISL B;  1BTH P;  2KAI I;  1P2Q B;  2UUY B;  1DEN A;  1TPA I;  2ODY E;  1YLC B;  1T7C B; 
#chains in the Genus database with same CATH homology
 2FI3 I;  2LFL A;  2ZVX A;  1BZX I;  4BD9 B;  1TOC R;  2UUX A;  1JV9 A;  3LDI A;  4PTI A;  3OFW A;  1FY8 I;  2FI5 I;  3BTW I;  1EJM B;  1P2K I;  2TGP I;  3CI7 A;  3BTH I;  2JOT A;  3AUG A;  2RA3 C;  3UOU B;  1BRB I;  1FAN A;  1F5R I;  1T8N B;  3TGJ I;  4Y0Z I;  4Y10 I;  1T8M B;  1YLD B;  3U1J E;  1PIT A;  1BZ5 A;  1ZR0 B;  5JB6 A;  2DDJ A;  1B0C A;  3T62 D;  1KNT A;  1YKT B;  1BPT A;  4DG4 C;  1KIG I;  1OA6 5;  1CO7 I;  4U32 X;  3AUH A;  1YC0 I;  3BTK I;  1F7Z I;  8PTI A;  2CA7 A;  2J6D A;  3BTG I;  3OTJ I;  2KCR A;  1UUB A;  1Y62 A;  3P92 E;  1BPI A;  4U30 W;  1EAW B;  1BUN B;  1MTN D;  5C67 C;  1AAP A;  1G6X A;  1TAW B;  4ISO B;  3L33 E;  1CBW D;  4NTY B;  1P2O B;  1T8L B;  2FTL I;  3AUE A;  6PTI A;  3FP6 I;  3BYB A;  9PTI A;  3GYM I;  3BTT I;  1BTI A;  4TPI I;  5PTI A;  3LDJ A;  4Y11 I;  2IJO I;  4ISN B;  3UIR C;  2FTM B;  1D0D B;  2W8X A;  1TFX C;  1KUN A;  1ADZ A;  1OA5 5;  4Y0Y I;  1JC6 A;  1DTX A;  1IRH A;  2M99 A;  1P2J I;  1P2M B;  4BQD A;  3AUD A;  3L3T E;  1BHC A;  2FI4 I;  1DTK A;  1D0D A;  3D65 I;  1ZJD B;  2HEX A;  2LFK A;  1AAL A;  1FAK I;  1T8O B;  1SHP A;  3AUB A;  3TGK I;  1QLQ A;  3AUI A;  3BTF I;  3M7Q B;  3FP8 I;  3BTD I;  1UUA A;  1NAG A;  3TGI I;  1DEM A;  1BIK A;  2KNT A;  4NTW B;  4WXV C;  1JV8 A;  2ZJX A;  1P2I I;  2PTC I;  3AUC A;  3P95 E;  2TPI I;  1BF0 A;  1LD5 A;  4BNR I;  3WNY A;  2M01 A;  1TCP A;  5JB4 A;  1BRC I;  1TAP A;  1K6U A;  3BTQ I;  5JB5 A;  1LD6 A;  4NTX B;  3BTE I;  1P2N B;  5JB7 A;  3TPI I;  3LDM A;  2DDI A;  1KTH A;  4WWY C;  7PTI A;  3FP7 J;  4DTG K;  1CA0 D;  2R9P E;  3BTM I;  4ISL B;  1BTH P;  2KAI I;  1P2Q B;  2UUY B;  1DEN A;  1TPA I;  2ODY E;  1YLC B;  1T7C B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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