3T6AA

Structure of the c-terminal domain of bcar3
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
308
structure length
308
Chain Sequence
TVSSFRPNEFESKFLPPENKPLETALLKRAKELFTNNDPKVIAQHVLSMDCRVARILGVSEEMRRNMGVSSGLELITLPHGHQLRLDIIERHNTMAIGIAVDILGCTGTLEDRAATLSKIIQVAVELKDSMGDLYSFSALMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKLLHEGRESTCVPPNNVSVPLLMPLVTLMERQAVTFEGTDMWEKNDQSCEIMLNHLATARFMAEAADSYRMNAERILAGFQPDEEMNEICKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signaling protein
molecule keywords Breast cancer anti-estrogen resistance protein 3
total genus 131
structure length 308
sequence length 308
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00617 RasGEF RasGEF domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.840.10 Mainly Alpha Orthogonal Bundle Son of Sevenless (SoS) protein; Chain S, domain 2 Ras guanine-nucleotide exchange factors catalytic domain 3t6aA00
2II0A 4MGKE 4URZS 3T6AA 4MGYE 4US2S 4US1S 4URWS 3QXLA 3KSYA 4MH0E 4NYIS 4MGZE 1XD2C 1XD4A 5CM8A 4NYJS 3T6GA 2IJES 4URXS 4JGWA 1BKDS 4MGIE 1NVXS 1NVUS 2BYVE 4URVS 1NVWS 4US0S 4F7ZA 4URYS 1NVVS 4URUS 4NYMS 5CM9A 4L9MA 3CF6E
chains in the Genus database with same CATH superfamily
2II0A 4MGKE 4URZS 3T6AA 4MGYE 4US2S 4US1S 4URWS 3QXLA 3KSYA 4MH0E 4NYIS 4MGZE 1XD2C 1XD4A 5CM8A 4NYJS 3T6GA 2IJES 4URXS 4JGWA 1BKDS 4MGIE 1NVXS 1NVUS 2BYVE 4URVS 1NVWS 4US0S 4F7ZA 4URYS 1NVVS 4URUS 4NYMS 5CM9A 4L9MA 3CF6E
chains in the Genus database with same CATH topology
2II0A 4MGKE 4URZS 3T6AA 4MGYE 4US2S 4US1S 4URWS 3QXLA 3KSYA 4MH0E 4NYIS 4MGZE 1XD2C 1XD4A 5CM8A 4NYJS 3T6GA 2IJES 4URXS 4JGWA 1BKDS 4MGIE 1NVXS 1NVUS 2BYVE 4URVS 1NVWS 4US0S 4F7ZA 4URYS 1NVVS 4URUS 4NYMS 5CM9A 4L9MA 3CF6E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2II0 A;  4MGK E;  4URZ S;  3T6A A;  4MGY E;  4US2 S;  4US1 S;  4URW S;  3QXL A;  3KSY A;  4MH0 E;  4NYI S;  4MGZ E;  1XD2 C;  1XD4 A;  5CM8 A;  4NYJ S;  3T6G A;  2IJE S;  4URX S;  4JGW A;  1BKD S;  4MGI E;  1NVX S;  1NVU S;  2BYV E;  4URV S;  1NVW S;  4US0 S;  4F7Z A;  4URY S;  1NVV S;  4URU S;  4NYM S;  5CM9 A;  4L9M A;  3CF6 E; 
#chains in the Genus database with same CATH topology
 2II0 A;  4MGK E;  4URZ S;  3T6A A;  4MGY E;  4US2 S;  4US1 S;  4URW S;  3QXL A;  3KSY A;  4MH0 E;  4NYI S;  4MGZ E;  1XD2 C;  1XD4 A;  5CM8 A;  4NYJ S;  3T6G A;  2IJE S;  4URX S;  4JGW A;  1BKD S;  4MGI E;  1NVX S;  1NVU S;  2BYV E;  4URV S;  1NVW S;  4US0 S;  4F7Z A;  4URY S;  1NVV S;  4URU S;  4NYM S;  5CM9 A;  4L9M A;  3CF6 E; 
#chains in the Genus database with same CATH homology
 2II0 A;  4MGK E;  4URZ S;  3T6A A;  4MGY E;  4US2 S;  4US1 S;  4URW S;  3QXL A;  3KSY A;  4MH0 E;  4NYI S;  4MGZ E;  1XD2 C;  1XD4 A;  5CM8 A;  4NYJ S;  3T6G A;  2IJE S;  4URX S;  4JGW A;  1BKD S;  4MGI E;  1NVX S;  1NVU S;  2BYV E;  4URV S;  1NVW S;  4US0 S;  4F7Z A;  4URY S;  1NVV S;  4URU S;  4NYM S;  5CM9 A;  4L9M A;  3CF6 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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