3TB3A

Crystal structure of the uch domain of uch-l5 with 6 residues deleted
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
Knots found
sequence length
220
structure length
204
Chain Sequence
EWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNAAATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Ubiquitin carboxyl-terminal hydrolase isozyme L5
publication title Length of the active-site crossover loop defines the substrate specificity of ubiquitin C-terminal hydrolases for ubiquitin chains.
pubmed doi rcsb
source organism Homo sapiens
total genus 68
structure length 204
sequence length 220
chains with identical sequence B
other databases KnotProt 2.0: S -31 -31
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2011-08-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01088 Peptidase_C12 Ubiquitin carboxyl-terminal hydrolase, family 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.532.10 Alpha Beta 3-Layer(aba) Sandwich Ubiquitin C-terminal Hydrolase UCH-l3 Peptidase C12, ubiquitin carboxyl-terminal hydrolase 3tb3A00
3IRTA 1UCHA 3TB3A 2LENA 3IHRA 3KW5A 1XD3A 1CMXA 4DM9A 4JKJA 3A7SA 3KVFA 4UELA 3RIIA 4IG7A 2ETLA 3RISA 4UEMA 3IFWA 4I6NA
chains in the Genus database with same CATH superfamily
3IRTA 1UCHA 3TB3A 2LENA 3IHRA 3KW5A 1XD3A 1CMXA 4DM9A 4JKJA 3A7SA 3KVFA 4UELA 3RIIA 4IG7A 2ETLA 3RISA 4UEMA 3IFWA 4I6NA
chains in the Genus database with same CATH topology
3IRTA 1UCHA 3TB3A 2LENA 3IHRA 3KW5A 1XD3A 1CMXA 4DM9A 4JKJA 3A7SA 3KVFA 4UELA 3RIIA 4IG7A 2ETLA 3RISA 4UEMA 3IFWA 4I6NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IRT A;  1UCH A;  3TB3 A;  2LEN A;  3IHR A;  3KW5 A;  1XD3 A;  1CMX A;  4DM9 A;  4JKJ A;  3A7S A;  3KVF A;  4UEL A;  3RII A;  4IG7 A;  2ETL A;  3RIS A;  4UEM A;  3IFW A;  4I6N A; 
#chains in the Genus database with same CATH topology
 3IRT A;  1UCH A;  3TB3 A;  2LEN A;  3IHR A;  3KW5 A;  1XD3 A;  1CMX A;  4DM9 A;  4JKJ A;  3A7S A;  3KVF A;  4UEL A;  3RII A;  4IG7 A;  2ETL A;  3RIS A;  4UEM A;  3IFW A;  4I6N A; 
#chains in the Genus database with same CATH homology
 3IRT A;  1UCH A;  3TB3 A;  2LEN A;  3IHR A;  3KW5 A;  1XD3 A;  1CMX A;  4DM9 A;  4JKJ A;  3A7S A;  3KVF A;  4UEL A;  3RII A;  4IG7 A;  2ETL A;  3RIS A;  4UEM A;  3IFW A;  4I6N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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