3TIWA

Crystal structure of p97n in complex with the c-terminus of gp78
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
165
structure length
160
Chain Sequence
RPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97.
pubmed doi rcsb
molecule keywords Transitional endoplasmic reticulum ATPase
molecule tags Protein transport/ligase
source organism Homo sapiens
total genus 45
structure length 160
sequence length 165
chains with identical sequence B
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2011-08-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 3tiwA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 3tiwA02
4AAYA 1H0HA 1PQFA 1TWHA 2VPWA 1H5NA 5T5MD 1SIWA 2R93A 1DMRA 2DMRA 3QQ8A 4QIWA 5GLFA 2VPZA 1TWAA 2E7ZA 3GTOA 2YUJA 1E60A 1TWGA 3OUGA 1PT1A 1FDIA 3DMRA 3HKZA 1QCSA 2PJHB 3HU3A 3HU1A 1E32A 2JIQA 2V45A 4KLNA 4AONB 2VUMA 1KQGA 5FTKA 1I50A 5DYIA 3IR6A 5FTNA 5C1BA 1PYQA 2WAQA 1WLFA 3QC8A 3CQZA 4CRZA 3PLXB 1R7RA 3QWZA 1Q16A 1OGYA 2NYAA 1DMSA 1FDOA 1UHEA 2JIPA 2Y0SA 1KQFA 3TM7B 3CF2A 1AW8B 2R92A 1EU1A 1VC3B 3QQ7A 3GTKA 1S3SA 5B6CA 3TIWA 2JIMA 2R7ZA 1Y4ZA 3H0GA 1QDNA 1TMOA 3GTLA 1E5VA 2PMZA 4C2MA 4D7ZB 2JA5A 1ZC1A 2JV2A 3FKIA 1YLEA 4KDIA 2NAPA 5EPPA 1TWFA 2IV2X 4CS0A 5T5ID 1PQEA 4AOKB 1IW7D 1Y1VA 3O5AA 3GTJA 2NVYA 2E2IA 1PPYA 2NVXA 5DYGA 2C45A 4DMRA 1PT0A 5FTMA 1E61A 5C18A 2YU9A 1R9TA 2JIRA 1CZ4A 3GTQA 1R27A 5FTJA 4GA6A 1E18A 2JA7A 1TWCA 1SFOA 4RV0A 4GA5A 4KO8A 1WCMA 4KDLA 1Y1WA 2VPYA 1CR5A 1Y5IA 3GTPA 5FTLA 3IR7A 3GTMA 2V3VA 2EEOB 3HU2A 4AZDA 1G8KA 1AA6A 3GTGA 1K83A 2B63A 1CZ5A 2JIOA 3IR5A 2JA6A 2VPXA 1PYUB 3ML1A 1UHDA 1G8JA 1PQHA 4AYBA 4CRYG 2KI8A 1I3QA 4KODA 2WB1A 2E2HA
chains in the Genus database with same CATH superfamily
2PICA 3LGAA 4AAYA 1H0HA 1PQFA 1TWHA 1OA9A 2VPWA 1H5NA 2G6GA 5T5MD 2LW6A 1O54A 1SIWA 4AS1A 2R93A 1DMRA 2DMRA 3QQ8A 4JJOA 4QIWA 5GLFA 2VPZA 1N10A 3ZGZA 1TWAA 2E7ZA 2YUJA 3GTOA 1E60A 2PWYA 1TWGA 5H4UA 2A69D 3OUGA 1PT1A 5GLXA 1FDIA 5GLYA 2A6HD 3SUJA 2BH0A 3CZBA 3DMRA 3FPRA 3HKZA 2PI8A 1QCSA 2A6ED 2PJHB 3HU1A 1E32A 2JIQA 3HU3A 4NOHA 4ARIA 2V45A 4FFTA 4KLNA 5D6WA 2AE0X 3X2PA 4AONB 2VUMA 1KQGA 5FTKA 1I50A 2XDPA 2GFAA 4AQ7A 2PNWA 5DYIA 3IR6A 5FTNA 5C1BA 1PYQA 2WAQA 1WLFA 3QC8A 3CQZA 3X2JA 4CRZA 2ENGA 3PLXB 2MM0A 1R7RA 3QWZA 4ARCA 3ENGA 1Q16A 1OGYA 1WC2A 3D30A 2NYAA 1DMSA 1FDOA 2KQAA 3X2MA 3X2HA 5CCBA 1UHEA 2JIPA 2Y0SA 4FG2A 3X2KA 3TM7B 1KQFA 2Q18X 1OA7A 3CF2A 1AW8B 2R92A 4JP7A 3SUMA 1EU1A 3M3GA 1VC3B 3QQ7A 1L8FA 3GTKA 1S3SA 2BE5D 5B6CA 3TIWA 2QQSA 2JIMA 2R7ZA 1Y4ZA 3H0GA 1QDNA 1TMOA 3GTLA 1ZYRD 1E5VA 2PMZA 4C2MA 4D7ZB 1ZC1A 2JA5A 2JV2A 2QQRA 3X2IA 3FKIA 1YLEA 3SUKA 1BW4A 3ZJTA 4FERA 5D6YA 4KDIA 5GM9A 2NAPA 5EPPA 2A68D 1TWFA 1YNJD 2G5DA 2B25A 2IV2X 4CS0A 5EQJB 5T5ID 1BW3A 1PQEA 4FIBA 4JP6A 4AOKB 1IW7D 1HD5A 1Y1VA 2PJJA 3O5AA 3GTJA 2NVYA 2E2IA 1PPYA 4UC4A 2NVXA 2O5JD 4FG4A 5DYGA 2Q1AX 2C45A 4DMRA 1PT0A 5FTMA 1E61A 5C18A 3LHDA 2YU9A 2GF7A 5D6XA 3FPUA 1R9TA 3X2LA 3X2GA 2JIRA 3BQBA 1YNND 1CZ4A 1SMYD 3GTQA 1R27A 5FTJA 3MB5A 4GA6A 2Q1DX 1E18A 4AVRA 2JA7A 1TWCA 1SFOA 2KY9A 4RV0A 4CQNA 4GA5A 4KO8A 5CD1A 1WCMA 2Q1CX 4KDLA 3SULA 1Y1WA 2VPYA 1Y5IA 1CR5A 3X2NA 3GTPA 5FTLA 3FPTA 5CCXA 3IR7A 3GTMA 4L48A 2GAEA 2V3VA 4JS7A 2MM2A 2EEOB 4ENGA 1I9GA 3HU2A 4AZDA 1G8KA 1AA6A 3ZJVA 3GTGA 1K83A 2B63A 3X2OA 1CZ5A 2JIOA 3IR5A 3ZJUA 2JA6A 2Q19X 4JCWA 2VPXA 1PYUB 3ML1A 4ZM7A 2YVLA 1UHDA 1G8JA 1PQHA 5ERGB 4AYBA 4CRYG 2KI8A 1I3QA 4KODA 2HCZX 2WB1A 2CW0D 2E2HA
chains in the Genus database with same CATH topology
2PICA 3LGAA 4AAYA 1H0HA 1PQFA 1TWHA 2VPWA 1H5NA 2G6GA 5T5MD 2LW6A 1O54A 1SIWA 4AS1A 2R93A 1DMRA 2DMRA 3QQ8A 4QIWA 5GLFA 2VPZA 3ZGZA 1TWAA 2E7ZA 2YUJA 3GTOA 1E60A 2PWYA 1TWGA 2A69D 3OUGA 1PT1A 1FDIA 2A6HD 3DMRA 3CZBA 3FPRA 3HKZA 2PI8A 1QCSA 2A6ED 2PJHB 3HU1A 1E32A 2JIQA 3HU3A 4NOHA 4ARIA 2V45A 5D6WA 4KLNA 2AE0X 4AONB 2VUMA 1KQGA 5FTKA 1I50A 2XDPA 2GFAA 4AQ7A 2PNWA 5DYIA 3IR6A 5FTNA 5C1BA 1PYQA 2WAQA 1WLFA 3QC8A 3CQZA 4CRZA 2YVLA 3PLXB 2MM0A 1R7RA 3QWZA 4ARCA 1Q16A 1OGYA 2NYAA 1DMSA 1FDOA 5CCBA 1UHEA 2JIPA 2Y0SA 1KQFA 3TM7B 2Q18X 3CF2A 1AW8B 2R92A 1EU1A 1VC3B 3QQ7A 3GTKA 1S3SA 2BE5D 5B6CA 3TIWA 2QQSA 2JIMA 2R7ZA 1Y4ZA 3H0GA 1QDNA 1TMOA 3GTLA 1ZYRD 1E5VA 2PMZA 4C2MA 4D7ZB 1ZC1A 2JA5A 2JV2A 2QQRA 3FKIA 1YLEA 3ZJTA 5D6YA 4KDIA 2NAPA 5EPPA 2A68D 1TWFA 1YNJD 2G5DA 2B25A 2IV2X 4CS0A 5EQJB 5T5ID 1PQEA 4FIBA 4AOKB 1IW7D 1Y1VA 3O5AA 2PJJA 3GTJA 2NVYA 2E2IA 1PPYA 4UC4A 2NVXA 2O5JD 5DYGA 2Q1AX 2C45A 4DMRA 1PT0A 5FTMA 1E61A 5C18A 3LHDA 2YU9A 2GF7A 5D6XA 3FPUA 1R9TA 2JIRA 3BQBA 1YNND 1CZ4A 1SMYD 3GTQA 1R27A 5FTJA 3MB5A 4GA6A 2Q1DX 1E18A 2JA7A 1TWCA 1SFOA 2KY9A 4RV0A 4CQNA 4GA5A 4KO8A 5CD1A 1WCMA 2Q1CX 4KDLA 1Y1WA 2VPYA 1CR5A 1Y5IA 3GTPA 5FTLA 3FPTA 5CCXA 3IR7A 3GTMA 2GAEA 2V3VA 2MM2A 2EEOB 1I9GA 3HU2A 4AZDA 1G8KA 1AA6A 3ZJVA 3GTGA 1K83A 2B63A 1CZ5A 2JIOA 3IR5A 3ZJUA 2JA6A 2Q19X 2VPXA 1PYUB 3ML1A 1UHDA 1G8JA 1PQHA 5ERGB 4AYBA 4CRYG 2KI8A 1I3QA 4KODA 2WB1A 2CW0D 2E2HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AAY A;  1H0H A;  1PQF A;  1TWH A;  2VPW A;  1H5N A;  5T5M D;  1SIW A;  2R93 A;  1DMR A;  2DMR A;  3QQ8 A;  4QIW A;  5GLF A;  2VPZ A;  1TWA A;  2E7Z A;  3GTO A;  2YUJ A;  1E60 A;  1TWG A;  3OUG A;  1PT1 A;  1FDI A;  3DMR A;  3HKZ A;  1QCS A;  2PJH B;  3HU3 A;  3HU1 A;  1E32 A;  2JIQ A;  2V45 A;  4KLN A;  4AON B;  2VUM A;  1KQG A;  5FTK A;  1I50 A;  5DYI A;  3IR6 A;  5FTN A;  5C1B A;  1PYQ A;  2WAQ A;  1WLF A;  3QC8 A;  3CQZ A;  4CRZ A;  3PLX B;  1R7R A;  3QWZ A;  1Q16 A;  1OGY A;  2NYA A;  1DMS A;  1FDO A;  1UHE A;  2JIP A;  2Y0S A;  1KQF A;  3TM7 B;  3CF2 A;  1AW8 B;  2R92 A;  1EU1 A;  1VC3 B;  3QQ7 A;  3GTK A;  1S3S A;  5B6C A;  3TIW A;  2JIM A;  2R7Z A;  1Y4Z A;  3H0G A;  1QDN A;  1TMO A;  3GTL A;  1E5V A;  2PMZ A;  4C2M A;  4D7Z B;  2JA5 A;  1ZC1 A;  2JV2 A;  3FKI A;  1YLE A;  4KDI A;  2NAP A;  5EPP A;  1TWF A;  2IV2 X;  4CS0 A;  5T5I D;  1PQE A;  4AOK B;  1IW7 D;  1Y1V A;  3O5A A;  3GTJ A;  2NVY A;  2E2I A;  1PPY A;  2NVX A;  5DYG A;  2C45 A;  4DMR A;  1PT0 A;  5FTM A;  1E61 A;  5C18 A;  2YU9 A;  1R9T A;  2JIR A;  1CZ4 A;  3GTQ A;  1R27 A;  5FTJ A;  4GA6 A;  1E18 A;  2JA7 A;  1TWC A;  1SFO A;  4RV0 A;  4GA5 A;  4KO8 A;  1WCM A;  4KDL A;  1Y1W A;  2VPY A;  1CR5 A;  1Y5I A;  3GTP A;  5FTL A;  3IR7 A;  3GTM A;  2V3V A;  2EEO B;  3HU2 A;  4AZD A;  1G8K A;  1AA6 A;  3GTG A;  1K83 A;  2B63 A;  1CZ5 A;  2JIO A;  3IR5 A;  2JA6 A;  2VPX A;  1PYU B;  3ML1 A;  1UHD A;  1G8J A;  1PQH A;  4AYB A;  4CRY G;  2KI8 A;  1I3Q A;  4KOD A;  2WB1 A;  2E2H A; 
#chains in the Genus database with same CATH topology
 2PIC A;  3LGA A;  4AAY A;  1H0H A;  1PQF A;  1TWH A;  1OA9 A;  2VPW A;  1H5N A;  2G6G A;  5T5M D;  2LW6 A;  1O54 A;  1SIW A;  4AS1 A;  2R93 A;  1DMR A;  2DMR A;  3QQ8 A;  4JJO A;  4QIW A;  5GLF A;  2VPZ A;  1N10 A;  3ZGZ A;  1TWA A;  2E7Z A;  2YUJ A;  3GTO A;  1E60 A;  2PWY A;  1TWG A;  5H4U A;  2A69 D;  3OUG A;  1PT1 A;  5GLX A;  1FDI A;  5GLY A;  2A6H D;  3SUJ A;  2BH0 A;  3CZB A;  3DMR A;  3FPR A;  3HKZ A;  2PI8 A;  1QCS A;  2A6E D;  2PJH B;  3HU1 A;  1E32 A;  2JIQ A;  3HU3 A;  4NOH A;  4ARI A;  2V45 A;  4FFT A;  4KLN A;  5D6W A;  2AE0 X;  3X2P A;  4AON B;  2VUM A;  1KQG A;  5FTK A;  1I50 A;  2XDP A;  2GFA A;  4AQ7 A;  2PNW A;  5DYI A;  3IR6 A;  5FTN A;  5C1B A;  1PYQ A;  2WAQ A;  1WLF A;  3QC8 A;  3CQZ A;  3X2J A;  4CRZ A;  2ENG A;  3PLX B;  2MM0 A;  1R7R A;  3QWZ A;  4ARC A;  3ENG A;  1Q16 A;  1OGY A;  1WC2 A;  3D30 A;  2NYA A;  1DMS A;  1FDO A;  2KQA A;  3X2M A;  3X2H A;  5CCB A;  1UHE A;  2JIP A;  2Y0S A;  4FG2 A;  3X2K A;  3TM7 B;  1KQF A;  2Q18 X;  1OA7 A;  3CF2 A;  1AW8 B;  2R92 A;  4JP7 A;  3SUM A;  1EU1 A;  3M3G A;  1VC3 B;  3QQ7 A;  1L8F A;  3GTK A;  1S3S A;  2BE5 D;  5B6C A;  3TIW A;  2QQS A;  2JIM A;  2R7Z A;  1Y4Z A;  3H0G A;  1QDN A;  1TMO A;  3GTL A;  1ZYR D;  1E5V A;  2PMZ A;  4C2M A;  4D7Z B;  1ZC1 A;  2JA5 A;  2JV2 A;  2QQR A;  3X2I A;  3FKI A;  1YLE A;  3SUK A;  1BW4 A;  3ZJT A;  4FER A;  5D6Y A;  4KDI A;  5GM9 A;  2NAP A;  5EPP A;  2A68 D;  1TWF A;  1YNJ D;  2G5D A;  2B25 A;  2IV2 X;  4CS0 A;  5EQJ B;  5T5I D;  1BW3 A;  1PQE A;  4FIB A;  4JP6 A;  4AOK B;  1IW7 D;  1HD5 A;  1Y1V A;  2PJJ A;  3O5A A;  3GTJ A;  2NVY A;  2E2I A;  1PPY A;  4UC4 A;  2NVX A;  2O5J D;  4FG4 A;  5DYG A;  2Q1A X;  2C45 A;  4DMR A;  1PT0 A;  5FTM A;  1E61 A;  5C18 A;  3LHD A;  2YU9 A;  2GF7 A;  5D6X A;  3FPU A;  1R9T A;  3X2L A;  3X2G A;  2JIR A;  3BQB A;  1YNN D;  1CZ4 A;  1SMY D;  3GTQ A;  1R27 A;  5FTJ A;  3MB5 A;  4GA6 A;  2Q1D X;  1E18 A;  4AVR A;  2JA7 A;  1TWC A;  1SFO A;  2KY9 A;  4RV0 A;  4CQN A;  4GA5 A;  4KO8 A;  5CD1 A;  1WCM A;  2Q1C X;  4KDL A;  3SUL A;  1Y1W A;  2VPY A;  1Y5I A;  1CR5 A;  3X2N A;  3GTP A;  5FTL A;  3FPT A;  5CCX A;  3IR7 A;  3GTM A;  4L48 A;  2GAE A;  2V3V A;  4JS7 A;  2MM2 A;  2EEO B;  4ENG A;  1I9G A;  3HU2 A;  4AZD A;  1G8K A;  1AA6 A;  3ZJV A;  3GTG A;  1K83 A;  2B63 A;  3X2O A;  1CZ5 A;  2JIO A;  3IR5 A;  3ZJU A;  2JA6 A;  2Q19 X;  4JCW A;  2VPX A;  1PYU B;  3ML1 A;  4ZM7 A;  2YVL A;  1UHD A;  1G8J A;  1PQH A;  5ERG B;  4AYB A;  4CRY G;  2KI8 A;  1I3Q A;  4KOD A;  2HCZ X;  2WB1 A;  2CW0 D;  2E2H A; 
#chains in the Genus database with same CATH homology
 2PIC A;  3LGA A;  4AAY A;  1H0H A;  1PQF A;  1TWH A;  2VPW A;  1H5N A;  2G6G A;  5T5M D;  2LW6 A;  1O54 A;  1SIW A;  4AS1 A;  2R93 A;  1DMR A;  2DMR A;  3QQ8 A;  4QIW A;  5GLF A;  2VPZ A;  3ZGZ A;  1TWA A;  2E7Z A;  2YUJ A;  3GTO A;  1E60 A;  2PWY A;  1TWG A;  2A69 D;  3OUG A;  1PT1 A;  1FDI A;  2A6H D;  3DMR A;  3CZB A;  3FPR A;  3HKZ A;  2PI8 A;  1QCS A;  2A6E D;  2PJH B;  3HU1 A;  1E32 A;  2JIQ A;  3HU3 A;  4NOH A;  4ARI A;  2V45 A;  5D6W A;  4KLN A;  2AE0 X;  4AON B;  2VUM A;  1KQG A;  5FTK A;  1I50 A;  2XDP A;  2GFA A;  4AQ7 A;  2PNW A;  5DYI A;  3IR6 A;  5FTN A;  5C1B A;  1PYQ A;  2WAQ A;  1WLF A;  3QC8 A;  3CQZ A;  4CRZ A;  2YVL A;  3PLX B;  2MM0 A;  1R7R A;  3QWZ A;  4ARC A;  1Q16 A;  1OGY A;  2NYA A;  1DMS A;  1FDO A;  5CCB A;  1UHE A;  2JIP A;  2Y0S A;  1KQF A;  3TM7 B;  2Q18 X;  3CF2 A;  1AW8 B;  2R92 A;  1EU1 A;  1VC3 B;  3QQ7 A;  3GTK A;  1S3S A;  2BE5 D;  5B6C A;  3TIW A;  2QQS A;  2JIM A;  2R7Z A;  1Y4Z A;  3H0G A;  1QDN A;  1TMO A;  3GTL A;  1ZYR D;  1E5V A;  2PMZ A;  4C2M A;  4D7Z B;  1ZC1 A;  2JA5 A;  2JV2 A;  2QQR A;  3FKI A;  1YLE A;  3ZJT A;  5D6Y A;  4KDI A;  2NAP A;  5EPP A;  2A68 D;  1TWF A;  1YNJ D;  2G5D A;  2B25 A;  2IV2 X;  4CS0 A;  5EQJ B;  5T5I D;  1PQE A;  4FIB A;  4AOK B;  1IW7 D;  1Y1V A;  3O5A A;  2PJJ A;  3GTJ A;  2NVY A;  2E2I A;  1PPY A;  4UC4 A;  2NVX A;  2O5J D;  5DYG A;  2Q1A X;  2C45 A;  4DMR A;  1PT0 A;  5FTM A;  1E61 A;  5C18 A;  3LHD A;  2YU9 A;  2GF7 A;  5D6X A;  3FPU A;  1R9T A;  2JIR A;  3BQB A;  1YNN D;  1CZ4 A;  1SMY D;  3GTQ A;  1R27 A;  5FTJ A;  3MB5 A;  4GA6 A;  2Q1D X;  1E18 A;  2JA7 A;  1TWC A;  1SFO A;  2KY9 A;  4RV0 A;  4CQN A;  4GA5 A;  4KO8 A;  5CD1 A;  1WCM A;  2Q1C X;  4KDL A;  1Y1W A;  2VPY A;  1CR5 A;  1Y5I A;  3GTP A;  5FTL A;  3FPT A;  5CCX A;  3IR7 A;  3GTM A;  2GAE A;  2V3V A;  2MM2 A;  2EEO B;  1I9G A;  3HU2 A;  4AZD A;  1G8K A;  1AA6 A;  3ZJV A;  3GTG A;  1K83 A;  2B63 A;  1CZ5 A;  2JIO A;  3IR5 A;  3ZJU A;  2JA6 A;  2Q19 X;  2VPX A;  1PYU B;  3ML1 A;  1UHD A;  1G8J A;  1PQH A;  5ERG B;  4AYB A;  4CRY G;  2KI8 A;  1I3Q A;  4KOD A;  2WB1 A;  2CW0 D;  2E2H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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