3TM2A

Crystal structure of mature thnt with a covalently bound product mimic
Total Genus 115
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
374
structure length
367
Chain Sequence
GIGGVPGPHNGLTDVPGVRVGHAGRTGDGWLTGVTVVLAPPGGAVAAVDVRGGGPGTRETDALDPRNLVQTIDAVVLTGGSAFGLDAAGGVAAWLEEQGRGFPVGADPSQVVPVVPAAALFDLGRGGTWRARPDAALGRAAVEAAAARPEGDPVEQGGVGAGTGAVVGGLKGGIGTASVVLDSGATVAALAAVNAAGSAVDPATGVLYGARTGLPGEFAGYGVPDAIGADTHARARARLAEAAEETARRRATTLAVVATDATLTRAQAQKLAGTAHDGLARAVRPVHLLSDGDTVFALSTGRRPLLPDRPDATAARAFGVHLEAGALNEVLAAGADVLTRAVVHAVLAATGVDTPGGVHPSYRELYA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords cysteine transferase
publication title Autoproteolytic Activation of ThnT Results in Structural Reorganization Necessary for Substrate Binding and Catalysis.
pubmed doi rcsb
source organism Streptomyces cattleya
total genus 115
structure length 367
sequence length 374
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03576 Peptidase_S58 Peptidase family S58
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.70.12 Alpha Beta 4-Layer Sandwich L-amino peptidase D-ALA esterase/amidase L-amino peptidase D-ALA esterase/amidase 3tm2A00
1VZ6A 1VZ8A 3TM1A 4IHEA 1B65A 3NFBA 3IT6A 3NDVA 3N33A 3S3UA 3TM2A 2YEPA 3N5IA 2VZKA 3IT4A 1VRAA 1VZ7A 3AXGA 3N2WA 4IHDA 2V4IA 2DRHA
chains in the Genus database with same CATH superfamily
1VZ6A 1VZ8A 3TM1A 4IHEA 1B65A 3NFBA 3IT6A 3NDVA 3N33A 3S3UA 3TM2A 2YEPA 3N5IA 2VZKA 3IT4A 1VRAA 1VZ7A 3AXGA 3N2WA 4IHDA 2V4IA 2DRHA
chains in the Genus database with same CATH topology
1VZ6A 1VZ8A 3TM1A 4IHEA 1B65A 3NFBA 3IT6A 3NDVA 3N33A 3S3UA 3TM2A 2YEPA 3N5IA 2VZKA 3IT4A 1VRAA 1VZ7A 3AXGA 3N2WA 4IHDA 2V4IA 2DRHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VZ6 A;  1VZ8 A;  3TM1 A;  4IHE A;  1B65 A;  3NFB A;  3IT6 A;  3NDV A;  3N33 A;  3S3U A;  3TM2 A;  2YEP A;  3N5I A;  2VZK A;  3IT4 A;  1VRA A;  1VZ7 A;  3AXG A;  3N2W A;  4IHD A;  2V4I A;  2DRH A; 
#chains in the Genus database with same CATH topology
 1VZ6 A;  1VZ8 A;  3TM1 A;  4IHE A;  1B65 A;  3NFB A;  3IT6 A;  3NDV A;  3N33 A;  3S3U A;  3TM2 A;  2YEP A;  3N5I A;  2VZK A;  3IT4 A;  1VRA A;  1VZ7 A;  3AXG A;  3N2W A;  4IHD A;  2V4I A;  2DRH A; 
#chains in the Genus database with same CATH homology
 1VZ6 A;  1VZ8 A;  3TM1 A;  4IHE A;  1B65 A;  3NFB A;  3IT6 A;  3NDV A;  3N33 A;  3S3U A;  3TM2 A;  2YEP A;  3N5I A;  2VZK A;  3IT4 A;  1VRA A;  1VZ7 A;  3AXG A;  3N2W A;  4IHD A;  2V4I A;  2DRH A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...