3TV5A

Crystal structure of the humanized carboxyltransferase domain of yeast acetyl-coa caroxylase in complex with compound 1
Total Genus 225
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
225
sequence length
716
structure length
696
Chain Sequence
LRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGASALNKVLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQQAGQVWFPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPEGTVEIKFRREKLLDTMNRLDDKYRKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHQVGEASRLEKIARIRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGLKLESFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion.
pubmed doi rcsb
source organism Saccharomyces cerevisiae s288c
molecule tags Ligase
molecule keywords Acetyl-CoA carboxylase
total genus 225
structure length 696
sequence length 716
chains with identical sequence B, C
ec nomenclature ec 6.3.4.14: Biotin carboxylase.
pdb deposition date 2011-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01039 Carboxyl_trans Carboxyl transferase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.460.10 Mainly Beta Beta Barrel ClpP/crotonase fold Biotin dependent carboxylase carboxyltransferase 3tv5A02
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 3tv5A01
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 3tv5A03
2GTRA 3TZ3A 5DU6A 4FN7A 3HINA 2ZL2A 1MJ3A 1FCFA 4WCZA 1UYVA 4GM2A 4L6WA 3K8XA 2J5GA 5INFA 2HW5A 3HP0A 2VSUA 3BEZA 3H81A 2PG8A 3T89A 4YLHA 2X24A 3H0QA 2IEXA 1YG8A 4RCNA 3IBBA 5C90A 3MOYA 4QIIA 4Z0MA 2NP9A 1TG6A 3GF3A 3GMAA 4U0GH 3Q7HA 3GKBA 4B3HA 3QXZA 4JFCA 4ELXA 2VSSA 3HE2A 4FN8A 4Q0GA 3GF7A 1XO6A 1W2XA 1Q51A 2Q34A 1N6DA 2DEOA 2ZL4A 3KTKA 2J5SA 3KTGA 4B3IA 1HNOA 1UYTA 3TVWA 4NNQA 5E0SH 4FB8A 3PGQA 1NZYA 3FF6A 2J5IB 2F9IB 1EY3A 3T8BA 4MOUA 3T3WA 4JCTA 2VREA 3Q0GA 4U1AA 3DJAA 1UYSA 5CTBA 3G64A 3U9TB 4L8KA 3K50A 1WDKA 1XNWA 3QREA 5G1SA 3LKEA 3HRXA 3T8AA 5FUSA 4IZCA 3H0JA 3R9QA 4KNPA 5C9GA 1OD2A 1ON3A 4FZWA 3R9TA 3QMJA 4IZDA 3MFMA 3PEAA 4ELWA 2F9YB 2W3PA 5DU8A 1XNYA 3RRVA 3RSIA 2C8TA 4JCRA 2WTBA 3MYBA 1J7XA 1TYFA 1VRGA 5E0NX 4OG1A 4EMMA 1Y7OA 2PBPA 2DUBA 2Q35A 3MT6A 3HLN1 4I42A 2QQ3A 1ON9A 4U0GA 3ST9A 2A7SA 2A81A 2J5II 4U0HA 4ZDFA 5E0SA 4JSBA 3P85A 2VSSF 4ZDEA 3P2LA 3WG5A 4ELSA 4JWVA 4FNDA 2X58A 3SLLA 3NJDA 3TT6A 4KD6A 3NJBA 3IB9A 1DUBA 4QFEA 3U9RB 1WDMA 3KTJA 4I52A 3V5IA 4KPKA 4OLQA 3QWDA 2VSUF 4K3WA 5DUFA 1OD4A 5DTPA 1DCIA 3TT7A 3QXIA 3TRRA 1PIXA 4ASIA 4ZU2A 4MXIA 2ZQRA 5INIA 1SG4A 3R6HA 2VSUC 4EMLA 3RSTA 2BZRA 1FC7A 1PJHA 4HC8A 4DI1A 5DZKH 3R9SA 3TLFA 3V5EA 3QK8A 3GLMA 4ZDDA 1YG6A 5INGA 3OMEA 4HNKA 3BPPA 2F9YA 5DUCA 4JVTA 2F6QA 4FNBA 1XNVA 3PZKA 4K2NA 4LK5A 4GHNA 1EF9A 2EJ5A 3BF0A 4B3JA 3OT6A 2Q2XA 5G1QA 5MGBA 3ZW9A 4MI2A 4EMPA 5JBWA 4JCQA 3LAOA 5CTCA 3QKAA 5G1RA 3TVUA 3STAA 3TV5A 5DL1A 2ZL0A 3QYRA 2PPYA 3ZWBA 2J5IA 2FW2A 1WZ8A 3M6MA 5DKPA 4WYOB 3I47A 3ZW8A 2J5GD 3KQFA 5IKLB 2FBMA 1UIYA 3JU1A 1K39A 1UYRA 3ISAA 2D3TA 1XX4A 4FZWC 3H0SA 3TDCA 2F9IA 4JJTA 3M6NA 4F47A 4Q1IA 2UZFA 4RYFH 5DZKA 1N6EA 4KWBA 4I4ZA 2FZSA 1N6FA 4ZDCA 3ZWCA 4ZDBA 3H0UA 2ZL3A 3ZWAA 1HNUA 5FIFA 3T88A 5JBXA 4U19A 4JCSA 1NZYB 2VX2A 2VSUE 3VIVA 5DU4A 4QIJA 4WZ8B 4FJWD 3OC7A 3KTHA 2A7KA 3Q0JA 3KTIA 3SWXA 3DORA 1RJNA 3IAVA 5KDRA 2CBYA 3N6RB 4G2RA 1Q52A 3P5MA 4JOTA 3H02A 2CE3A 1X0UA 3PE8A 4JYJA 1FC6A 1HZDA 5KJPA 1WDLA 4K29A 3FDUA 1SZOA 1O8UA 1EF8A 4OMRA 2VSSE 4JYLA 1K32A 4U18A 4IZBA 5DTWA 4NEKA 3U9SB 3Q1TA 3R0OA 4RYFA 1JXZA 3L3SA 1FC9A 1RJMA 5KDRB 2F6IA 2ZQQA
chains in the Genus database with same CATH superfamily
2GTRA 3TZ3A 5DU6A 4FN7A 3HINA 2ZL2A 1MJ3A 1FCFA 4WCZA 1UYVA 4GM2A 4L6WA 3K8XA 2J5GA 5INFA 2HW5A 4HDTA 3HP0A 2VSUA 3BEZA 3H81A 2PG8A 3T89A 4YLHA 2X24A 3H0QA 2IEXA 3BPTA 1YG8A 4RCNA 3IBBA 5C90A 3MOYA 4QIIA 4Z0MA 4NARA 2NP9A 1TG6A 3GF3A 3GMAA 4U0GH 3Q7HA 3GKBA 4B3HA 3QXZA 4JFCA 4ELXA 2VSSA 3HE2A 4FN8A 4Q0GA 3GF7A 1XO6A 1W2XA 1Q51A 2Q34A 1N6DA 2DEOA 2ZL4A 3KTKA 2J5SA 3KTGA 4B3IA 1HNOA 1UYTA 3TVWA 4NNQA 5E0SH 4FB8A 3PGQA 1NZYA 3FF6A 2J5IB 2F9IB 1EY3A 3T8BA 4MOUA 3T3WA 4JCTA 2VREA 3Q0GA 4U1AA 3DJAA 1UYSA 5CTBA 3G64A 3U9TB 4L8KA 3K50A 1WDKA 1XNWA 3QREA 5G1SA 3LKEA 3HRXA 2YJGA 3T8AA 5FUSA 4IZCA 3H0JA 3R9QA 4KNPA 5C9GA 1OD2A 1ON3A 4FZWA 3R9TA 3QMJA 4IZDA 3MFMA 3PEAA 4ELWA 2F9YB 2W3PA 5DU8A 1XNYA 3RRVA 3RSIA 2C8TA 4J2UA 4JCRA 2WTBA 3MYBA 1J7XA 1TYFA 1VRGA 5E0NX 4OG1A 4EMMA 1Y7OA 2PBPA 2DUBA 2Q35A 3MT6A 3HLN1 4I42A 2QQ3A 1ON9A 4U0GA 3ST9A 2A7SA 2A81A 2J5II 4U0HA 4ZDFA 5E0SA 4JSBA 3P85A 2VSSF 4ZDEA 3P2LA 3WG5A 4ELSA 4JWVA 4FNDA 2X58A 3SLLA 3NJDA 3TT6A 4KD6A 3NJBA 3IB9A 1DUBA 4QFEA 3U9RB 1WDMA 3KTJA 4I52A 3V5IA 4KPKA 4OLQA 3QWDA 2VSUF 4K3WA 5DUFA 1OD4A 5DTPA 1DCIA 3TT7A 5HUQA 3QXIA 3TRRA 1PIXA 4ASIA 4ZU2A 4MXIA 2ZQRA 5INIA 1SG4A 3R6HA 2VSUC 4EMLA 3RSTA 2BZRA 1FC7A 1PJHA 4HC8A 4DI1A 5DZKH 3R9SA 3TLFA 3V5EA 3QK8A 3GLMA 4ZDDA 1YG6A 5INGA 3OMEA 4HNKA 3BPPA 2F9YA 5DUCA 4JVTA 2F6QA 4FNBA 1XNVA 3PZKA 4K2NA 4LK5A 4GHNA 1EF9A 2EJ5A 3BF0A 4B3JA 3OT6A 2Q2XA 5G1QA 5MGBA 3ZW9A 4MI2A 4EMPA 5JBWA 4JCQA 3LAOA 5CTCA 3QKAA 5G1RA 3TVUA 3STAA 3TV5A 5DL1A 2ZL0A 3QYRA 2PPYA 3ZWBA 2J5IA 2FW2A 1WZ8A 3M6MA 5DKPA 4WYOB 3I47A 3ZW8A 2J5GD 3KQFA 5IKLB 2FBMA 1UIYA 3JU1A 1K39A 1UYRA 3ISAA 2D3TA 1XX4A 4FZWC 3H0SA 3TDCA 2F9IA 4JJTA 3M6NA 4F47A 4Q1IA 2UZFA 4RYFH 5DZKA 1N6EA 4KWBA 4I4ZA 2FZSA 1N6FA 4ZDCA 3ZWCA 4ZDBA 3H0UA 2ZL3A 3ZWAA 1HNUA 5FIFA 3T88A 5JBXA 4U19A 4JCSA 1NZYB 2VX2A 2VSUE 3VIVA 5DU4A 4QIJA 4WZ8B 4FJWD 3OC7A 3KTHA 2A7KA 3Q0JA 3KTIA 3SWXA 3DORA 1RJNA 3IAVA 5KDRA 2CBYA 3N6RB 4G2RA 1Q52A 3P5MA 4JOTA 3H02A 2CE3A 1X0UA 3PE8A 4JYJA 1FC6A 1HZDA 5KJPA 1WDLA 4K29A 3FDUA 1SZOA 1O8UA 1EF8A 4OMRA 2VSSE 4JYLA 1K32A 4U18A 4IZBA 5DTWA 4NEKA 3U9SB 3Q1TA 3R0OA 4RYFA 1JXZA 3L3SA 1FC9A 1RJMA 5KDRB 2F6IA 2ZQQA
chains in the Genus database with same CATH topology
2GTRA 3TZ3A 5DU6A 4FN7A 3HINA 2ZL2A 1MJ3A 1FCFA 4WCZA 1UYVA 4GM2A 4L6WA 3K8XA 2J5GA 5INFA 2HW5A 4HDTA 3HP0A 2VSUA 3BEZA 3H81A 2PG8A 3T89A 4YLHA 2X24A 3H0QA 2IEXA 3BPTA 1YG8A 4RCNA 3IBBA 5C90A 3MOYA 4QIIA 4Z0MA 4NARA 2NP9A 1TG6A 3GF3A 3GMAA 4U0GH 3Q7HA 3GKBA 4B3HA 3QXZA 4JFCA 4ELXA 2VSSA 3HE2A 4FN8A 4Q0GA 3GF7A 1XO6A 1W2XA 1Q51A 2Q34A 1N6DA 2DEOA 2ZL4A 3KTKA 2J5SA 3KTGA 4B3IA 1HNOA 1UYTA 3TVWA 4NNQA 5E0SH 4FB8A 3PGQA 1NZYA 3FF6A 2J5IB 2F9IB 1EY3A 3T8BA 4MOUA 3T3WA 4JCTA 2VREA 3Q0GA 4U1AA 3DJAA 1UYSA 5CTBA 3G64A 3U9TB 4L8KA 3K50A 1WDKA 1XNWA 3QREA 5G1SA 3LKEA 3HRXA 2YJGA 3T8AA 5FUSA 4IZCA 3H0JA 3R9QA 4KNPA 5C9GA 1OD2A 1ON3A 4FZWA 3R9TA 3QMJA 4IZDA 3MFMA 3PEAA 4ELWA 2F9YB 2W3PA 5DU8A 1XNYA 3RRVA 3RSIA 2C8TA 4J2UA 4JCRA 2WTBA 3MYBA 1J7XA 1TYFA 1VRGA 5E0NX 4OG1A 4EMMA 1Y7OA 2PBPA 2DUBA 2Q35A 3MT6A 3HLN1 4I42A 2QQ3A 1ON9A 4U0GA 3ST9A 2A7SA 2A81A 2J5II 4U0HA 4ZDFA 5E0SA 4JSBA 3P85A 2VSSF 4ZDEA 3P2LA 3WG5A 4ELSA 4JWVA 4FNDA 2X58A 3SLLA 3NJDA 3TT6A 4KD6A 3NJBA 3IB9A 1DUBA 4QFEA 3U9RB 1WDMA 3KTJA 4I52A 3V5IA 4KPKA 4OLQA 3QWDA 2VSUF 4K3WA 5DUFA 1OD4A 5DTPA 1DCIA 3TT7A 5HUQA 3QXIA 3TRRA 1PIXA 4ASIA 4ZU2A 4MXIA 2ZQRA 5INIA 1SG4A 3R6HA 2VSUC 4EMLA 3RSTA 2BZRA 1FC7A 1PJHA 4HC8A 4DI1A 5DZKH 3R9SA 3TLFA 3V5EA 3QK8A 3GLMA 4ZDDA 1YG6A 5INGA 3OMEA 4HNKA 3BPPA 2F9YA 5DUCA 4JVTA 2F6QA 4FNBA 1XNVA 3PZKA 4K2NA 4LK5A 4GHNA 1EF9A 2EJ5A 3BF0A 4B3JA 3OT6A 2Q2XA 5G1QA 5MGBA 3ZW9A 4MI2A 4EMPA 5JBWA 4JCQA 3LAOA 5CTCA 3QKAA 5G1RA 3TVUA 3STAA 3TV5A 5DL1A 2ZL0A 3QYRA 2PPYA 3ZWBA 2J5IA 2FW2A 1WZ8A 3M6MA 5DKPA 4WYOB 3I47A 3ZW8A 2J5GD 3KQFA 5IKLB 2FBMA 1UIYA 3JU1A 1K39A 1UYRA 3ISAA 2D3TA 1XX4A 4FZWC 3H0SA 3TDCA 2F9IA 4JJTA 3M6NA 4F47A 4Q1IA 2UZFA 4RYFH 5DZKA 1N6EA 4KWBA 4I4ZA 2FZSA 1N6FA 4ZDCA 3ZWCA 4ZDBA 3H0UA 2ZL3A 3ZWAA 1HNUA 5FIFA 3T88A 5JBXA 4U19A 4JCSA 1NZYB 2VX2A 2VSUE 3VIVA 5DU4A 4QIJA 4WZ8B 4FJWD 3OC7A 3KTHA 2A7KA 3Q0JA 3KTIA 3SWXA 3DORA 1RJNA 3IAVA 5KDRA 2CBYA 3N6RB 4G2RA 1Q52A 3P5MA 4JOTA 3H02A 2CE3A 1X0UA 3PE8A 4JYJA 1FC6A 1HZDA 5KJPA 1WDLA 4K29A 3FDUA 1SZOA 1O8UA 1EF8A 4OMRA 2VSSE 4JYLA 1K32A 4U18A 4IZBA 5DTWA 4NEKA 3U9SB 3Q1TA 3R0OA 4RYFA 1JXZA 3L3SA 1FC9A 1RJMA 5KDRB 2F6IA 2ZQQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GTR A;  3TZ3 A;  5DU6 A;  4FN7 A;  3HIN A;  2ZL2 A;  1MJ3 A;  1FCF A;  4WCZ A;  1UYV A;  4GM2 A;  4L6W A;  3K8X A;  2J5G A;  5INF A;  2HW5 A;  3HP0 A;  2VSU A;  3BEZ A;  3H81 A;  2PG8 A;  3T89 A;  4YLH A;  2X24 A;  3H0Q A;  2IEX A;  1YG8 A;  4RCN A;  3IBB A;  5C90 A;  3MOY A;  4QII A;  4Z0M A;  2NP9 A;  1TG6 A;  3GF3 A;  3GMA A;  4U0G H;  3Q7H A;  3GKB A;  4B3H A;  3QXZ A;  4JFC A;  4ELX A;  2VSS A;  3HE2 A;  4FN8 A;  4Q0G A;  3GF7 A;  1XO6 A;  1W2X A;  1Q51 A;  2Q34 A;  1N6D A;  2DEO A;  2ZL4 A;  3KTK A;  2J5S A;  3KTG A;  4B3I A;  1HNO A;  1UYT A;  3TVW A;  4NNQ A;  5E0S H;  4FB8 A;  3PGQ A;  1NZY A;  3FF6 A;  2J5I B;  2F9I B;  1EY3 A;  3T8B A;  4MOU A;  3T3W A;  4JCT A;  2VRE A;  3Q0G A;  4U1A A;  3DJA A;  1UYS A;  5CTB A;  3G64 A;  3U9T B;  4L8K A;  3K50 A;  1WDK A;  1XNW A;  3QRE A;  5G1S A;  3LKE A;  3HRX A;  3T8A A;  5FUS A;  4IZC A;  3H0J A;  3R9Q A;  4KNP A;  5C9G A;  1OD2 A;  1ON3 A;  4FZW A;  3R9T A;  3QMJ A;  4IZD A;  3MFM A;  3PEA A;  4ELW A;  2F9Y B;  2W3P A;  5DU8 A;  1XNY A;  3RRV A;  3RSI A;  2C8T A;  4JCR A;  2WTB A;  3MYB A;  1J7X A;  1TYF A;  1VRG A;  5E0N X;  4OG1 A;  4EMM A;  1Y7O A;  2PBP A;  2DUB A;  2Q35 A;  3MT6 A;  3HLN 1;  4I42 A;  2QQ3 A;  1ON9 A;  4U0G A;  3ST9 A;  2A7S A;  2A81 A;  2J5I I;  4U0H A;  4ZDF A;  5E0S A;  4JSB A;  3P85 A;  2VSS F;  4ZDE A;  3P2L A;  3WG5 A;  4ELS A;  4JWV A;  4FND A;  2X58 A;  3SLL A;  3NJD A;  3TT6 A;  4KD6 A;  3NJB A;  3IB9 A;  1DUB A;  4QFE A;  3U9R B;  1WDM A;  3KTJ A;  4I52 A;  3V5I A;  4KPK A;  4OLQ A;  3QWD A;  2VSU F;  4K3W A;  5DUF A;  1OD4 A;  5DTP A;  1DCI A;  3TT7 A;  3QXI A;  3TRR A;  1PIX A;  4ASI A;  4ZU2 A;  4MXI A;  2ZQR A;  5INI A;  1SG4 A;  3R6H A;  2VSU C;  4EML A;  3RST A;  2BZR A;  1FC7 A;  1PJH A;  4HC8 A;  4DI1 A;  5DZK H;  3R9S A;  3TLF A;  3V5E A;  3QK8 A;  3GLM A;  4ZDD A;  1YG6 A;  5ING A;  3OME A;  4HNK A;  3BPP A;  2F9Y A;  5DUC A;  4JVT A;  2F6Q A;  4FNB A;  1XNV A;  3PZK A;  4K2N A;  4LK5 A;  4GHN A;  1EF9 A;  2EJ5 A;  3BF0 A;  4B3J A;  3OT6 A;  2Q2X A;  5G1Q A;  5MGB A;  3ZW9 A;  4MI2 A;  4EMP A;  5JBW A;  4JCQ A;  3LAO A;  5CTC A;  3QKA A;  5G1R A;  3TVU A;  3STA A;  3TV5 A;  5DL1 A;  2ZL0 A;  3QYR A;  2PPY A;  3ZWB A;  2J5I A;  2FW2 A;  1WZ8 A;  3M6M A;  5DKP A;  4WYO B;  3I47 A;  3ZW8 A;  2J5G D;  3KQF A;  5IKL B;  2FBM A;  1UIY A;  3JU1 A;  1K39 A;  1UYR A;  3ISA A;  2D3T A;  1XX4 A;  4FZW C;  3H0S A;  3TDC A;  2F9I A;  4JJT A;  3M6N A;  4F47 A;  4Q1I A;  2UZF A;  4RYF H;  5DZK A;  1N6E A;  4KWB A;  4I4Z A;  2FZS A;  1N6F A;  4ZDC A;  3ZWC A;  4ZDB A;  3H0U A;  2ZL3 A;  3ZWA A;  1HNU A;  5FIF A;  3T88 A;  5JBX A;  4U19 A;  4JCS A;  1NZY B;  2VX2 A;  2VSU E;  3VIV A;  5DU4 A;  4QIJ A;  4WZ8 B;  4FJW D;  3OC7 A;  3KTH A;  2A7K A;  3Q0J A;  3KTI A;  3SWX A;  3DOR A;  1RJN A;  3IAV A;  5KDR A;  2CBY A;  3N6R B;  4G2R A;  1Q52 A;  3P5M A;  4JOT A;  3H02 A;  2CE3 A;  1X0U A;  3PE8 A;  4JYJ A;  1FC6 A;  1HZD A;  5KJP A;  1WDL A;  4K29 A;  3FDU A;  1SZO A;  1O8U A;  1EF8 A;  4OMR A;  2VSS E;  4JYL A;  1K32 A;  4U18 A;  4IZB A;  5DTW A;  4NEK A;  3U9S B;  3Q1T A;  3R0O A;  4RYF A;  1JXZ A;  3L3S A;  1FC9 A;  1RJM A;  5KDR B;  2F6I A;  2ZQQ A; 
#chains in the Genus database with same CATH topology
 2GTR A;  3TZ3 A;  5DU6 A;  4FN7 A;  3HIN A;  2ZL2 A;  1MJ3 A;  1FCF A;  4WCZ A;  1UYV A;  4GM2 A;  4L6W A;  3K8X A;  2J5G A;  5INF A;  2HW5 A;  4HDT A;  3HP0 A;  2VSU A;  3BEZ A;  3H81 A;  2PG8 A;  3T89 A;  4YLH A;  2X24 A;  3H0Q A;  2IEX A;  3BPT A;  1YG8 A;  4RCN A;  3IBB A;  5C90 A;  3MOY A;  4QII A;  4Z0M A;  4NAR A;  2NP9 A;  1TG6 A;  3GF3 A;  3GMA A;  4U0G H;  3Q7H A;  3GKB A;  4B3H A;  3QXZ A;  4JFC A;  4ELX A;  2VSS A;  3HE2 A;  4FN8 A;  4Q0G A;  3GF7 A;  1XO6 A;  1W2X A;  1Q51 A;  2Q34 A;  1N6D A;  2DEO A;  2ZL4 A;  3KTK A;  2J5S A;  3KTG A;  4B3I A;  1HNO A;  1UYT A;  3TVW A;  4NNQ A;  5E0S H;  4FB8 A;  3PGQ A;  1NZY A;  3FF6 A;  2J5I B;  2F9I B;  1EY3 A;  3T8B A;  4MOU A;  3T3W A;  4JCT A;  2VRE A;  3Q0G A;  4U1A A;  3DJA A;  1UYS A;  5CTB A;  3G64 A;  3U9T B;  4L8K A;  3K50 A;  1WDK A;  1XNW A;  3QRE A;  5G1S A;  3LKE A;  3HRX A;  2YJG A;  3T8A A;  5FUS A;  4IZC A;  3H0J A;  3R9Q A;  4KNP A;  5C9G A;  1OD2 A;  1ON3 A;  4FZW A;  3R9T A;  3QMJ A;  4IZD A;  3MFM A;  3PEA A;  4ELW A;  2F9Y B;  2W3P A;  5DU8 A;  1XNY A;  3RRV A;  3RSI A;  2C8T A;  4J2U A;  4JCR A;  2WTB A;  3MYB A;  1J7X A;  1TYF A;  1VRG A;  5E0N X;  4OG1 A;  4EMM A;  1Y7O A;  2PBP A;  2DUB A;  2Q35 A;  3MT6 A;  3HLN 1;  4I42 A;  2QQ3 A;  1ON9 A;  4U0G A;  3ST9 A;  2A7S A;  2A81 A;  2J5I I;  4U0H A;  4ZDF A;  5E0S A;  4JSB A;  3P85 A;  2VSS F;  4ZDE A;  3P2L A;  3WG5 A;  4ELS A;  4JWV A;  4FND A;  2X58 A;  3SLL A;  3NJD A;  3TT6 A;  4KD6 A;  3NJB A;  3IB9 A;  1DUB A;  4QFE A;  3U9R B;  1WDM A;  3KTJ A;  4I52 A;  3V5I A;  4KPK A;  4OLQ A;  3QWD A;  2VSU F;  4K3W A;  5DUF A;  1OD4 A;  5DTP A;  1DCI A;  3TT7 A;  5HUQ A;  3QXI A;  3TRR A;  1PIX A;  4ASI A;  4ZU2 A;  4MXI A;  2ZQR A;  5INI A;  1SG4 A;  3R6H A;  2VSU C;  4EML A;  3RST A;  2BZR A;  1FC7 A;  1PJH A;  4HC8 A;  4DI1 A;  5DZK H;  3R9S A;  3TLF A;  3V5E A;  3QK8 A;  3GLM A;  4ZDD A;  1YG6 A;  5ING A;  3OME A;  4HNK A;  3BPP A;  2F9Y A;  5DUC A;  4JVT A;  2F6Q A;  4FNB A;  1XNV A;  3PZK A;  4K2N A;  4LK5 A;  4GHN A;  1EF9 A;  2EJ5 A;  3BF0 A;  4B3J A;  3OT6 A;  2Q2X A;  5G1Q A;  5MGB A;  3ZW9 A;  4MI2 A;  4EMP A;  5JBW A;  4JCQ A;  3LAO A;  5CTC A;  3QKA A;  5G1R A;  3TVU A;  3STA A;  3TV5 A;  5DL1 A;  2ZL0 A;  3QYR A;  2PPY A;  3ZWB A;  2J5I A;  2FW2 A;  1WZ8 A;  3M6M A;  5DKP A;  4WYO B;  3I47 A;  3ZW8 A;  2J5G D;  3KQF A;  5IKL B;  2FBM A;  1UIY A;  3JU1 A;  1K39 A;  1UYR A;  3ISA A;  2D3T A;  1XX4 A;  4FZW C;  3H0S A;  3TDC A;  2F9I A;  4JJT A;  3M6N A;  4F47 A;  4Q1I A;  2UZF A;  4RYF H;  5DZK A;  1N6E A;  4KWB A;  4I4Z A;  2FZS A;  1N6F A;  4ZDC A;  3ZWC A;  4ZDB A;  3H0U A;  2ZL3 A;  3ZWA A;  1HNU A;  5FIF A;  3T88 A;  5JBX A;  4U19 A;  4JCS A;  1NZY B;  2VX2 A;  2VSU E;  3VIV A;  5DU4 A;  4QIJ A;  4WZ8 B;  4FJW D;  3OC7 A;  3KTH A;  2A7K A;  3Q0J A;  3KTI A;  3SWX A;  3DOR A;  1RJN A;  3IAV A;  5KDR A;  2CBY A;  3N6R B;  4G2R A;  1Q52 A;  3P5M A;  4JOT A;  3H02 A;  2CE3 A;  1X0U A;  3PE8 A;  4JYJ A;  1FC6 A;  1HZD A;  5KJP A;  1WDL A;  4K29 A;  3FDU A;  1SZO A;  1O8U A;  1EF8 A;  4OMR A;  2VSS E;  4JYL A;  1K32 A;  4U18 A;  4IZB A;  5DTW A;  4NEK A;  3U9S B;  3Q1T A;  3R0O A;  4RYF A;  1JXZ A;  3L3S A;  1FC9 A;  1RJM A;  5KDR B;  2F6I A;  2ZQQ A; 
#chains in the Genus database with same CATH homology
 2GTR A;  3TZ3 A;  5DU6 A;  4FN7 A;  3HIN A;  2ZL2 A;  1MJ3 A;  1FCF A;  4WCZ A;  1UYV A;  4GM2 A;  4L6W A;  3K8X A;  2J5G A;  5INF A;  2HW5 A;  4HDT A;  3HP0 A;  2VSU A;  3BEZ A;  3H81 A;  2PG8 A;  3T89 A;  4YLH A;  2X24 A;  3H0Q A;  2IEX A;  3BPT A;  1YG8 A;  4RCN A;  3IBB A;  5C90 A;  3MOY A;  4QII A;  4Z0M A;  4NAR A;  2NP9 A;  1TG6 A;  3GF3 A;  3GMA A;  4U0G H;  3Q7H A;  3GKB A;  4B3H A;  3QXZ A;  4JFC A;  4ELX A;  2VSS A;  3HE2 A;  4FN8 A;  4Q0G A;  3GF7 A;  1XO6 A;  1W2X A;  1Q51 A;  2Q34 A;  1N6D A;  2DEO A;  2ZL4 A;  3KTK A;  2J5S A;  3KTG A;  4B3I A;  1HNO A;  1UYT A;  3TVW A;  4NNQ A;  5E0S H;  4FB8 A;  3PGQ A;  1NZY A;  3FF6 A;  2J5I B;  2F9I B;  1EY3 A;  3T8B A;  4MOU A;  3T3W A;  4JCT A;  2VRE A;  3Q0G A;  4U1A A;  3DJA A;  1UYS A;  5CTB A;  3G64 A;  3U9T B;  4L8K A;  3K50 A;  1WDK A;  1XNW A;  3QRE A;  5G1S A;  3LKE A;  3HRX A;  2YJG A;  3T8A A;  5FUS A;  4IZC A;  3H0J A;  3R9Q A;  4KNP A;  5C9G A;  1OD2 A;  1ON3 A;  4FZW A;  3R9T A;  3QMJ A;  4IZD A;  3MFM A;  3PEA A;  4ELW A;  2F9Y B;  2W3P A;  5DU8 A;  1XNY A;  3RRV A;  3RSI A;  2C8T A;  4J2U A;  4JCR A;  2WTB A;  3MYB A;  1J7X A;  1TYF A;  1VRG A;  5E0N X;  4OG1 A;  4EMM A;  1Y7O A;  2PBP A;  2DUB A;  2Q35 A;  3MT6 A;  3HLN 1;  4I42 A;  2QQ3 A;  1ON9 A;  4U0G A;  3ST9 A;  2A7S A;  2A81 A;  2J5I I;  4U0H A;  4ZDF A;  5E0S A;  4JSB A;  3P85 A;  2VSS F;  4ZDE A;  3P2L A;  3WG5 A;  4ELS A;  4JWV A;  4FND A;  2X58 A;  3SLL A;  3NJD A;  3TT6 A;  4KD6 A;  3NJB A;  3IB9 A;  1DUB A;  4QFE A;  3U9R B;  1WDM A;  3KTJ A;  4I52 A;  3V5I A;  4KPK A;  4OLQ A;  3QWD A;  2VSU F;  4K3W A;  5DUF A;  1OD4 A;  5DTP A;  1DCI A;  3TT7 A;  5HUQ A;  3QXI A;  3TRR A;  1PIX A;  4ASI A;  4ZU2 A;  4MXI A;  2ZQR A;  5INI A;  1SG4 A;  3R6H A;  2VSU C;  4EML A;  3RST A;  2BZR A;  1FC7 A;  1PJH A;  4HC8 A;  4DI1 A;  5DZK H;  3R9S A;  3TLF A;  3V5E A;  3QK8 A;  3GLM A;  4ZDD A;  1YG6 A;  5ING A;  3OME A;  4HNK A;  3BPP A;  2F9Y A;  5DUC A;  4JVT A;  2F6Q A;  4FNB A;  1XNV A;  3PZK A;  4K2N A;  4LK5 A;  4GHN A;  1EF9 A;  2EJ5 A;  3BF0 A;  4B3J A;  3OT6 A;  2Q2X A;  5G1Q A;  5MGB A;  3ZW9 A;  4MI2 A;  4EMP A;  5JBW A;  4JCQ A;  3LAO A;  5CTC A;  3QKA A;  5G1R A;  3TVU A;  3STA A;  3TV5 A;  5DL1 A;  2ZL0 A;  3QYR A;  2PPY A;  3ZWB A;  2J5I A;  2FW2 A;  1WZ8 A;  3M6M A;  5DKP A;  4WYO B;  3I47 A;  3ZW8 A;  2J5G D;  3KQF A;  5IKL B;  2FBM A;  1UIY A;  3JU1 A;  1K39 A;  1UYR A;  3ISA A;  2D3T A;  1XX4 A;  4FZW C;  3H0S A;  3TDC A;  2F9I A;  4JJT A;  3M6N A;  4F47 A;  4Q1I A;  2UZF A;  4RYF H;  5DZK A;  1N6E A;  4KWB A;  4I4Z A;  2FZS A;  1N6F A;  4ZDC A;  3ZWC A;  4ZDB A;  3H0U A;  2ZL3 A;  3ZWA A;  1HNU A;  5FIF A;  3T88 A;  5JBX A;  4U19 A;  4JCS A;  1NZY B;  2VX2 A;  2VSU E;  3VIV A;  5DU4 A;  4QIJ A;  4WZ8 B;  4FJW D;  3OC7 A;  3KTH A;  2A7K A;  3Q0J A;  3KTI A;  3SWX A;  3DOR A;  1RJN A;  3IAV A;  5KDR A;  2CBY A;  3N6R B;  4G2R A;  1Q52 A;  3P5M A;  4JOT A;  3H02 A;  2CE3 A;  1X0U A;  3PE8 A;  4JYJ A;  1FC6 A;  1HZD A;  5KJP A;  1WDL A;  4K29 A;  3FDU A;  1SZO A;  1O8U A;  1EF8 A;  4OMR A;  2VSS E;  4JYL A;  1K32 A;  4U18 A;  4IZB A;  5DTW A;  4NEK A;  3U9S B;  3Q1T A;  3R0O A;  4RYF A;  1JXZ A;  3L3S A;  1FC9 A;  1RJM A;  5KDR B;  2F6I A;  2ZQQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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