3U73U

Crystal structure of stabilized human upar mutant in complex with atf
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
280
structure length
269
Chain Sequence
LRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTCSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMCHIDVSCCTKSGCNHPDLDVQY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the urokinase receptor in a ligand-free form.
pubmed doi rcsb
molecule keywords Urokinase plasminogen activator surface receptor
molecule tags Hydrolase/hydrolase receptor
source organism Homo sapiens
total genus 59
structure length 269
sequence length 280
ec nomenclature
pdb deposition date 2011-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
U PF00021 UPAR_LY6 u-PAR/Ly-6 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 3u73U01
2.10.60.10 Mainly Beta Ribbon CD59 CD59 3u73U03
2.10.60.10 Mainly Beta Ribbon CD59 CD59 3u73U02
1IJCA 4OM5A 1F8UB 5DO6A 1QKEA 1REWC 1MR6A 2HLRA 1CREA 1VB0A 2MJ0A 3BT1U 2H7ZB 3KFDE 3LAQU 1QM7A 4DO8A 1FRAA 4XJJA 2CCXA 2HLQA 1KC4A 1LSIA 1FASA 2H7ZA 4FAOE 2H64C 2VLWA 4FAOC 1QKDA 3EBXA 2LA1A 2PJYC 1I02A 2MUPA 2FD6U 1TXAA 1V6PA 2QJAC 2MFAA 1F94A 4EY8B 2ABXA 1LJZA 1KBTA 1IDIA 2CDXA 2QJBC 1B41B 1HC9B 1HAJA 2L03A 2JQPA 2H5FA 3ERAA 2L5SA 1NEAA 1PLOA 3BT2U 2GOOB 1TFSA 4ZQYA 1CDRA 2CTXA 1KL8A 1NORA 1HOYA 1XT3A 4UY2C 2BTXA 1CTXA 4HQPF 4BIKB 4QTIU 3QB4B 2UX2A 1IQ9A 1CRFA 1ERGA 1W6BA 1ES7B 1RL5A 2I9BE 1BTEA 1CODA 1JE9A 1LXGA 1ABTA 2MHYA 1KTZB 1TXBA 2JVEA 5DU1A 1CCQA 1IKCA 1CDQA 1S4YA 1KU6B 2H62D 3KFDI 1L4WA 2N99A 4AEAA 1KBSA 2CRSA 3PLCA 1HC9A 1M9ZA 1FSCA 2J8BA 1NTNA 1YWHA 3NDSA 1TGXA 6EBXA 1RGJA 1CVOA 1CDTA 1IDGA 4LFTA 3U73U 1ERAA 1NYSA 1CB9A 1LX5B 1DRSA 3EVSC 1KS6A 2H64B 2MJYA 4IYEA 4RUDA 2PJYB 1IDLA 1JGKA 5DZ5A 1CHVS 1KXIA 5IMTD 1CDSA 2CRTA 3FEVA 1FSSB 2K3GA 2X8BB 1NYUA 1MAHF 2MJ4A 3NEQA 3U74U 5EBXA 3HH7A 2NBTA 1CXNA 4OM4A 4P7UA 1JBDA 1IK8A 1COEA 2H62C 2QC1A 1FFJA 2MUOA 4BDTB 1UG4A 2LCRA 1KFHA 1NTXA 1BXPA 2UWRA 1H0JA 1ONJA 1IDHA 3VTSA 2H8UA 2OFSA 2QJ9C 1KBAA 1HAAA 5IMYC 1LXHA 1CXOA 1ZADA 3NH7A 2BHIA 2GOOC 1NXBA 2ERAA 1FF4A 1G6MA
chains in the Genus database with same CATH superfamily
1IJCA 4OM5A 1F8UB 5DO6A 1QKEA 1REWC 1MR6A 2HLRA 1CREA 1VB0A 2MJ0A 3BT1U 2H7ZB 3KFDE 3LAQU 1QM7A 4DO8A 1FRAA 4XJJA 2CCXA 2HLQA 1KC4A 1LSIA 1FASA 2H7ZA 4FAOE 2H64C 2VLWA 4FAOC 1QKDA 3EBXA 2LA1A 2PJYC 1I02A 2MUPA 2FD6U 4KSNA 1TXAA 1V6PA 2QJAC 2MFAA 1F94A 4EY8B 2ABXA 1LJZA 1KBTA 1IDIA 2CDXA 2QJBC 1B41B 1HC9B 1HAJA 2L03A 2JQPA 2H5FA 3ERAA 2L5SA 1NEAA 1PLOA 3BT2U 2GOOB 1TFSA 4ZQYA 1CDRA 2CTXA 1KL8A 1NORA 1HOYA 1XT3A 4UY2C 2BTXA 1CTXA 4HQPF 4BIKB 4QTIU 3QB4B 2UX2A 1IQ9A 1CRFA 1ERGA 1W6BA 1ES7B 1RL5A 2I9BE 1BTEA 1CODA 1JE9A 1LXGA 1ABTA 2MHYA 1KTZB 1TXBA 2JVEA 5DU1A 1CCQA 1IKCA 1CDQA 1S4YA 1KU6B 2H62D 3KFDI 1L4WA 2N99A 4AEAA 1KBSA 2CRSA 3PLCA 1HC9A 1M9ZA 1FSCA 2J8BA 1NTNA 1YWHA 3NDSA 1TGXA 6EBXA 1RGJA 1CVOA 1CDTA 1IDGA 4LFTA 3U73U 1ERAA 1NYSA 1CB9A 1LX5B 1DRSA 3EVSC 1KS6A 2H64B 2MJYA 4IYEA 4RUDA 2PJYB 1IDLA 1JGKA 5DZ5A 1CHVS 1KXIA 5IMTD 1CDSA 2CRTA 3FEVA 1FSSB 2K3GA 2X8BB 1NYUA 1MAHF 2MJ4A 3NEQA 3U74U 5EBXA 3HH7A 2NBTA 1CXNA 4OM4A 4P7UA 1JBDA 1IK8A 1COEA 2H62C 2QC1A 1FFJA 2MUOA 4BDTB 1UG4A 2LCRA 1KFHA 1NTXA 1BXPA 2UWRA 1H0JA 1ONJA 1IDHA 3VTSA 2H8UA 2OFSA 2QJ9C 1KBAA 1HAAA 5IMYC 1LXHA 1CXOA 1ZADA 3NH7A 2BHIA 2GOOC 1NXBA 2ERAA 1FF4A 1G6MA
chains in the Genus database with same CATH topology
1IJCA 4OM5A 1F8UB 5DO6A 1QKEA 1REWC 1MR6A 2HLRA 1CREA 1VB0A 2MJ0A 3BT1U 2H7ZB 3KFDE 3LAQU 1QM7A 4DO8A 1FRAA 4XJJA 2CCXA 2HLQA 1KC4A 1LSIA 1FASA 2H7ZA 4FAOE 2H64C 2VLWA 4FAOC 1QKDA 3EBXA 2LA1A 2PJYC 1I02A 2MUPA 2FD6U 4KSNA 1TXAA 1V6PA 2QJAC 2MFAA 1F94A 4EY8B 2ABXA 1LJZA 1KBTA 1IDIA 2CDXA 2QJBC 1B41B 1HC9B 1HAJA 2L03A 2JQPA 2H5FA 3ERAA 2L5SA 1NEAA 1PLOA 3BT2U 2GOOB 1TFSA 4ZQYA 1CDRA 2CTXA 1KL8A 1NORA 1HOYA 1XT3A 4UY2C 2BTXA 1CTXA 4HQPF 4BIKB 4QTIU 3QB4B 2UX2A 1IQ9A 1CRFA 1ERGA 1W6BA 1ES7B 1RL5A 2I9BE 1BTEA 1CODA 1JE9A 1LXGA 1ABTA 2MHYA 1KTZB 1TXBA 2JVEA 5DU1A 1CCQA 1IKCA 1CDQA 1S4YA 1KU6B 2H62D 3KFDI 1L4WA 2N99A 4AEAA 1KBSA 2CRSA 3PLCA 1HC9A 1M9ZA 1FSCA 2J8BA 1NTNA 1YWHA 3NDSA 1TGXA 6EBXA 1RGJA 1CVOA 1CDTA 1IDGA 4LFTA 3U73U 1ERAA 1NYSA 1CB9A 1LX5B 1DRSA 3EVSC 1KS6A 2H64B 2MJYA 4IYEA 4RUDA 2PJYB 1IDLA 1JGKA 5DZ5A 1CHVS 1KXIA 5IMTD 1CDSA 2CRTA 3FEVA 1FSSB 2K3GA 2X8BB 1NYUA 1MAHF 2MJ4A 3NEQA 3U74U 5EBXA 3HH7A 2NBTA 1CXNA 4OM4A 4P7UA 1JBDA 1IK8A 1COEA 2H62C 2QC1A 1FFJA 2MUOA 4BDTB 1UG4A 2LCRA 1KFHA 1NTXA 1BXPA 2UWRA 1H0JA 1ONJA 1IDHA 3VTSA 2H8UA 2OFSA 2QJ9C 1KBAA 1HAAA 5IMYC 1LXHA 1CXOA 1ZADA 3NH7A 2BHIA 2GOOC 1NXBA 2ERAA 1FF4A 1G6MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IJC A;  4OM5 A;  1F8U B;  5DO6 A;  1QKE A;  1REW C;  1MR6 A;  2HLR A;  1CRE A;  1VB0 A;  2MJ0 A;  3BT1 U;  2H7Z B;  3KFD E;  3LAQ U;  1QM7 A;  4DO8 A;  1FRA A;  4XJJ A;  2CCX A;  2HLQ A;  1KC4 A;  1LSI A;  1FAS A;  2H7Z A;  4FAO E;  2H64 C;  2VLW A;  4FAO C;  1QKD A;  3EBX A;  2LA1 A;  2PJY C;  1I02 A;  2MUP A;  2FD6 U;  1TXA A;  1V6P A;  2QJA C;  2MFA A;  1F94 A;  4EY8 B;  2ABX A;  1LJZ A;  1KBT A;  1IDI A;  2CDX A;  2QJB C;  1B41 B;  1HC9 B;  1HAJ A;  2L03 A;  2JQP A;  2H5F A;  3ERA A;  2L5S A;  1NEA A;  1PLO A;  3BT2 U;  2GOO B;  1TFS A;  4ZQY A;  1CDR A;  2CTX A;  1KL8 A;  1NOR A;  1HOY A;  1XT3 A;  4UY2 C;  2BTX A;  1CTX A;  4HQP F;  4BIK B;  4QTI U;  3QB4 B;  2UX2 A;  1IQ9 A;  1CRF A;  1ERG A;  1W6B A;  1ES7 B;  1RL5 A;  2I9B E;  1BTE A;  1COD A;  1JE9 A;  1LXG A;  1ABT A;  2MHY A;  1KTZ B;  1TXB A;  2JVE A;  5DU1 A;  1CCQ A;  1IKC A;  1CDQ A;  1S4Y A;  1KU6 B;  2H62 D;  3KFD I;  1L4W A;  2N99 A;  4AEA A;  1KBS A;  2CRS A;  3PLC A;  1HC9 A;  1M9Z A;  1FSC A;  2J8B A;  1NTN A;  1YWH A;  3NDS A;  1TGX A;  6EBX A;  1RGJ A;  1CVO A;  1CDT A;  1IDG A;  4LFT A;  3U73 U;  1ERA A;  1NYS A;  1CB9 A;  1LX5 B;  1DRS A;  3EVS C;  1KS6 A;  2H64 B;  2MJY A;  4IYE A;  4RUD A;  2PJY B;  1IDL A;  1JGK A;  5DZ5 A;  1CHV S;  1KXI A;  5IMT D;  1CDS A;  2CRT A;  3FEV A;  1FSS B;  2K3G A;  2X8B B;  1NYU A;  1MAH F;  2MJ4 A;  3NEQ A;  3U74 U;  5EBX A;  3HH7 A;  2NBT A;  1CXN A;  4OM4 A;  4P7U A;  1JBD A;  1IK8 A;  1COE A;  2H62 C;  2QC1 A;  1FFJ A;  2MUO A;  4BDT B;  1UG4 A;  2LCR A;  1KFH A;  1NTX A;  1BXP A;  2UWR A;  1H0J A;  1ONJ A;  1IDH A;  3VTS A;  2H8U A;  2OFS A;  2QJ9 C;  1KBA A;  1HAA A;  5IMY C;  1LXH A;  1CXO A;  1ZAD A;  3NH7 A;  2BHI A;  2GOO C;  1NXB A;  2ERA A;  1FF4 A;  1G6M A; 
#chains in the Genus database with same CATH topology
 1IJC A;  4OM5 A;  1F8U B;  5DO6 A;  1QKE A;  1REW C;  1MR6 A;  2HLR A;  1CRE A;  1VB0 A;  2MJ0 A;  3BT1 U;  2H7Z B;  3KFD E;  3LAQ U;  1QM7 A;  4DO8 A;  1FRA A;  4XJJ A;  2CCX A;  2HLQ A;  1KC4 A;  1LSI A;  1FAS A;  2H7Z A;  4FAO E;  2H64 C;  2VLW A;  4FAO C;  1QKD A;  3EBX A;  2LA1 A;  2PJY C;  1I02 A;  2MUP A;  2FD6 U;  4KSN A;  1TXA A;  1V6P A;  2QJA C;  2MFA A;  1F94 A;  4EY8 B;  2ABX A;  1LJZ A;  1KBT A;  1IDI A;  2CDX A;  2QJB C;  1B41 B;  1HC9 B;  1HAJ A;  2L03 A;  2JQP A;  2H5F A;  3ERA A;  2L5S A;  1NEA A;  1PLO A;  3BT2 U;  2GOO B;  1TFS A;  4ZQY A;  1CDR A;  2CTX A;  1KL8 A;  1NOR A;  1HOY A;  1XT3 A;  4UY2 C;  2BTX A;  1CTX A;  4HQP F;  4BIK B;  4QTI U;  3QB4 B;  2UX2 A;  1IQ9 A;  1CRF A;  1ERG A;  1W6B A;  1ES7 B;  1RL5 A;  2I9B E;  1BTE A;  1COD A;  1JE9 A;  1LXG A;  1ABT A;  2MHY A;  1KTZ B;  1TXB A;  2JVE A;  5DU1 A;  1CCQ A;  1IKC A;  1CDQ A;  1S4Y A;  1KU6 B;  2H62 D;  3KFD I;  1L4W A;  2N99 A;  4AEA A;  1KBS A;  2CRS A;  3PLC A;  1HC9 A;  1M9Z A;  1FSC A;  2J8B A;  1NTN A;  1YWH A;  3NDS A;  1TGX A;  6EBX A;  1RGJ A;  1CVO A;  1CDT A;  1IDG A;  4LFT A;  3U73 U;  1ERA A;  1NYS A;  1CB9 A;  1LX5 B;  1DRS A;  3EVS C;  1KS6 A;  2H64 B;  2MJY A;  4IYE A;  4RUD A;  2PJY B;  1IDL A;  1JGK A;  5DZ5 A;  1CHV S;  1KXI A;  5IMT D;  1CDS A;  2CRT A;  3FEV A;  1FSS B;  2K3G A;  2X8B B;  1NYU A;  1MAH F;  2MJ4 A;  3NEQ A;  3U74 U;  5EBX A;  3HH7 A;  2NBT A;  1CXN A;  4OM4 A;  4P7U A;  1JBD A;  1IK8 A;  1COE A;  2H62 C;  2QC1 A;  1FFJ A;  2MUO A;  4BDT B;  1UG4 A;  2LCR A;  1KFH A;  1NTX A;  1BXP A;  2UWR A;  1H0J A;  1ONJ A;  1IDH A;  3VTS A;  2H8U A;  2OFS A;  2QJ9 C;  1KBA A;  1HAA A;  5IMY C;  1LXH A;  1CXO A;  1ZAD A;  3NH7 A;  2BHI A;  2GOO C;  1NXB A;  2ERA A;  1FF4 A;  1G6M A; 
#chains in the Genus database with same CATH homology
 1IJC A;  4OM5 A;  1F8U B;  5DO6 A;  1QKE A;  1REW C;  1MR6 A;  2HLR A;  1CRE A;  1VB0 A;  2MJ0 A;  3BT1 U;  2H7Z B;  3KFD E;  3LAQ U;  1QM7 A;  4DO8 A;  1FRA A;  4XJJ A;  2CCX A;  2HLQ A;  1KC4 A;  1LSI A;  1FAS A;  2H7Z A;  4FAO E;  2H64 C;  2VLW A;  4FAO C;  1QKD A;  3EBX A;  2LA1 A;  2PJY C;  1I02 A;  2MUP A;  2FD6 U;  4KSN A;  1TXA A;  1V6P A;  2QJA C;  2MFA A;  1F94 A;  4EY8 B;  2ABX A;  1LJZ A;  1KBT A;  1IDI A;  2CDX A;  2QJB C;  1B41 B;  1HC9 B;  1HAJ A;  2L03 A;  2JQP A;  2H5F A;  3ERA A;  2L5S A;  1NEA A;  1PLO A;  3BT2 U;  2GOO B;  1TFS A;  4ZQY A;  1CDR A;  2CTX A;  1KL8 A;  1NOR A;  1HOY A;  1XT3 A;  4UY2 C;  2BTX A;  1CTX A;  4HQP F;  4BIK B;  4QTI U;  3QB4 B;  2UX2 A;  1IQ9 A;  1CRF A;  1ERG A;  1W6B A;  1ES7 B;  1RL5 A;  2I9B E;  1BTE A;  1COD A;  1JE9 A;  1LXG A;  1ABT A;  2MHY A;  1KTZ B;  1TXB A;  2JVE A;  5DU1 A;  1CCQ A;  1IKC A;  1CDQ A;  1S4Y A;  1KU6 B;  2H62 D;  3KFD I;  1L4W A;  2N99 A;  4AEA A;  1KBS A;  2CRS A;  3PLC A;  1HC9 A;  1M9Z A;  1FSC A;  2J8B A;  1NTN A;  1YWH A;  3NDS A;  1TGX A;  6EBX A;  1RGJ A;  1CVO A;  1CDT A;  1IDG A;  4LFT A;  3U73 U;  1ERA A;  1NYS A;  1CB9 A;  1LX5 B;  1DRS A;  3EVS C;  1KS6 A;  2H64 B;  2MJY A;  4IYE A;  4RUD A;  2PJY B;  1IDL A;  1JGK A;  5DZ5 A;  1CHV S;  1KXI A;  5IMT D;  1CDS A;  2CRT A;  3FEV A;  1FSS B;  2K3G A;  2X8B B;  1NYU A;  1MAH F;  2MJ4 A;  3NEQ A;  3U74 U;  5EBX A;  3HH7 A;  2NBT A;  1CXN A;  4OM4 A;  4P7U A;  1JBD A;  1IK8 A;  1COE A;  2H62 C;  2QC1 A;  1FFJ A;  2MUO A;  4BDT B;  1UG4 A;  2LCR A;  1KFH A;  1NTX A;  1BXP A;  2UWR A;  1H0J A;  1ONJ A;  1IDH A;  3VTS A;  2H8U A;  2OFS A;  2QJ9 C;  1KBA A;  1HAA A;  5IMY C;  1LXH A;  1CXO A;  1ZAD A;  3NH7 A;  2BHI A;  2GOO C;  1NXB A;  2ERA A;  1FF4 A;  1G6M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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