3UAIA

Structure of the shq1-cbf5-nop10-gar1 complex from saccharomyces cerevisiae
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
361
structure length
357
Chain Sequence
DTSEWPLLLKNFDKLLVRSGHYTPIPAGSSPLKRDLKSYISSGVINLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHDALKDEKDLGRSLENLTGALFQRPPLKRQLRVRTIYESNLIEFDNKRNLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGALSENDNMVTLHDVMDAQWVYDNTRDESYLRSIIQPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIELYDEIVLITTKGEAIAVAIAQMSTVDLASCDHGVVASVKRCIMERDLYPRRWGLGPVAQKKKQMKADGKLDKYGRVNENT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords H/ACA ribonucleoprotein complex subunit 4
publication title Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Isomerase/chaperone
total genus 94
structure length 357
sequence length 361
ec nomenclature ec 5.4.99.-:
pdb deposition date 2011-10-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 3uaiA02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 3uaiA01
1KSKA 3LWOA 1WXWA 1K8WA 1R3FA 1Q7HA 1ZL3A 3MQKA 2AB4A 1IT7A 1QYUA 2I82A 1SQWA 3LDFA 1V9KA 1PRZA 1IQ8A 2CX0A 4Q1TA 2P38A 1R3EA 1T5YA 2J5VA 3VSEA 4LGTA 3LWQA 3LWRA 2RFKA 3HAXA 2HVYA 3HJWA 1ZE1A 1KSVA 1SGVA 1J2BA 1V9FA 2AS0A 1ZS7A 1XPIA 3HJYA 1IT8A 1WXXA 2APOA 2J5TA 4LABA 2EY4A 3U28A 2B78A 1ZE2A 2CWWA 3DH3A 3LWVA 2Q07A 3UAIA 3D79A 1KSLA 2AUSA 2ISTA 4DMGA 3C0KA 3LWPA 2CX1A
chains in the Genus database with same CATH superfamily
2ANEA 1S04A 2CX0A 2P38A 2J5VA 2KKUA 1SGVA 2AS0A 1WXXA 2Z0TA 2EY4A 3U28A 2B78A 1ZE2A 3LWVA 1XNEA 3C0KA 3LWPA 2CX1A 2DP9A 1WXWA 3M6XA 1ZL3A 3MQKA 3M6WA 2I82A 1V9KA 1IQ8A 1R3EA 2RFKA 3HJYA 3HJWA 1ZE1A 1KSVA 1J2BA 1V9FA 2E5OA 4TZ4C 2APOA 1WK2A 2CWWA 3IUWA 2Q07A 3LJCA 3UAIA 3D79A 3M65A 1SI7A 3LWOA 1K8WA 2AB4A 1QYUA 1SQWA 2FRXA 1PRZA 1ZBOA 3M6VA 4CI1B 1T5YA 1SZWA 3VSEA 3LWQA 3HAXA 2HVYA 1SB7A 1ZS7A 1XPIA 3ZV0C 4LABA 3DH3A 1Z2ZA 2ISTA 1KSKA 1R3FA 1Q7HA 4CI3B 1IT7A 4CI2B 3M6UA 3LDFA 4Q1TA 3LWRA 4LGTA 3M4XA 1TE7A 1IT8A 2J5TA 1UOYA 2AUSA 1KSLA 4DMGA
chains in the Genus database with same CATH topology
1SI7A 1KSKA 3LWOA 1WXWA 1K8WA 1R3FA 1Q7HA 1ZL3A 3MQKA 2AB4A 1IT7A 1QYUA 2I82A 1SQWA 3LDFA 1V9KA 1PRZA 1IQ8A 2CX0A 4Q1TA 2P38A 1R3EA 1T5YA 1SZWA 2J5VA 3VSEA 4LGTA 3LWQA 3LWRA 2RFKA 3HAXA 2HVYA 3HJWA 1ZE1A 1KSVA 1SGVA 1J2BA 1V9FA 2AS0A 1ZS7A 1SB7A 1XPIA 3HJYA 1IT8A 1WXXA 2APOA 2J5TA 4LABA 2EY4A 1Z2ZA 2B78A 1ZE2A 2CWWA 3U28A 3LWVA 3DH3A 2Q07A 3UAIA 3D79A 1KSLA 2AUSA 2ISTA 4DMGA 3C0KA 3LWPA 2CX1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KSK A;  3LWO A;  1WXW A;  1K8W A;  1R3F A;  1Q7H A;  1ZL3 A;  3MQK A;  2AB4 A;  1IT7 A;  1QYU A;  2I82 A;  1SQW A;  3LDF A;  1V9K A;  1PRZ A;  1IQ8 A;  2CX0 A;  4Q1T A;  2P38 A;  1R3E A;  1T5Y A;  2J5V A;  3VSE A;  4LGT A;  3LWQ A;  3LWR A;  2RFK A;  3HAX A;  2HVY A;  3HJW A;  1ZE1 A;  1KSV A;  1SGV A;  1J2B A;  1V9F A;  2AS0 A;  1ZS7 A;  1XPI A;  3HJY A;  1IT8 A;  1WXX A;  2APO A;  2J5T A;  4LAB A;  2EY4 A;  3U28 A;  2B78 A;  1ZE2 A;  2CWW A;  3DH3 A;  3LWV A;  2Q07 A;  3UAI A;  3D79 A;  1KSL A;  2AUS A;  2IST A;  4DMG A;  3C0K A;  3LWP A;  2CX1 A; 
#chains in the Genus database with same CATH topology
 2ANE A;  1S04 A;  2CX0 A;  2P38 A;  2J5V A;  2KKU A;  1SGV A;  2AS0 A;  1WXX A;  2Z0T A;  2EY4 A;  3U28 A;  2B78 A;  1ZE2 A;  3LWV A;  1XNE A;  3C0K A;  3LWP A;  2CX1 A;  2DP9 A;  1WXW A;  3M6X A;  1ZL3 A;  3MQK A;  3M6W A;  2I82 A;  1V9K A;  1IQ8 A;  1R3E A;  2RFK A;  3HJY A;  3HJW A;  1ZE1 A;  1KSV A;  1J2B A;  1V9F A;  2E5O A;  4TZ4 C;  2APO A;  1WK2 A;  2CWW A;  3IUW A;  2Q07 A;  3LJC A;  3UAI A;  3D79 A;  3M65 A;  1SI7 A;  3LWO A;  1K8W A;  2AB4 A;  1QYU A;  1SQW A;  2FRX A;  1PRZ A;  1ZBO A;  3M6V A;  4CI1 B;  1T5Y A;  1SZW A;  3VSE A;  3LWQ A;  3HAX A;  2HVY A;  1SB7 A;  1ZS7 A;  1XPI A;  3ZV0 C;  4LAB A;  3DH3 A;  1Z2Z A;  2IST A;  1KSK A;  1R3F A;  1Q7H A;  4CI3 B;  1IT7 A;  4CI2 B;  3M6U A;  3LDF A;  4Q1T A;  3LWR A;  4LGT A;  3M4X A;  1TE7 A;  1IT8 A;  2J5T A;  1UOY A;  2AUS A;  1KSL A;  4DMG A; 
#chains in the Genus database with same CATH homology
 1SI7 A;  1KSK A;  3LWO A;  1WXW A;  1K8W A;  1R3F A;  1Q7H A;  1ZL3 A;  3MQK A;  2AB4 A;  1IT7 A;  1QYU A;  2I82 A;  1SQW A;  3LDF A;  1V9K A;  1PRZ A;  1IQ8 A;  2CX0 A;  4Q1T A;  2P38 A;  1R3E A;  1T5Y A;  1SZW A;  2J5V A;  3VSE A;  4LGT A;  3LWQ A;  3LWR A;  2RFK A;  3HAX A;  2HVY A;  3HJW A;  1ZE1 A;  1KSV A;  1SGV A;  1J2B A;  1V9F A;  2AS0 A;  1ZS7 A;  1SB7 A;  1XPI A;  3HJY A;  1IT8 A;  1WXX A;  2APO A;  2J5T A;  4LAB A;  2EY4 A;  1Z2Z A;  2B78 A;  1ZE2 A;  2CWW A;  3U28 A;  3LWV A;  3DH3 A;  2Q07 A;  3UAI A;  3D79 A;  1KSL A;  2AUS A;  2IST A;  4DMG A;  3C0K A;  3LWP A;  2CX1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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