3UAIA

Structure of the shq1-cbf5-nop10-gar1 complex from saccharomyces cerevisiae
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
361
structure length
357
Chain Sequence
DTSEWPLLLKNFDKLLVRSGHYTPIPAGSSPLKRDLKSYISSGVINLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHDALKDEKDLGRSLENLTGALFQRPPLKRQLRVRTIYESNLIEFDNKRNLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGALSENDNMVTLHDVMDAQWVYDNTRDESYLRSIIQPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIELYDEIVLITTKGEAIAVAIAQMSTVDLASCDHGVVASVKRCIMERDLYPRRWGLGPVAQKKKQMKADGKLDKYGRVNENT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita
pubmed doi rcsb
molecule tags Isomerase/chaperone
source organism Saccharomyces cerevisiae
molecule keywords H/ACA ribonucleoprotein complex subunit 4
total genus 94
structure length 357
sequence length 361
ec nomenclature ec 5.4.99.-:
pdb deposition date 2011-10-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 3uaiA02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 3uaiA01
1KSVA 1K8WA 2CWWA 2CX1A 1R3FA 2J5VA 4Q1TA 3LWRA 2EY4A 3VSEA 1R3EA 2P38A 3C0KA 2CX0A 1ZE1A 3LDFA 2APOA 2B78A 3LWPA 2RFKA 3LWVA 2AUSA 2HVYA 1PRZA 1QYUA 1IQ8A 1KSKA 1IT7A 1V9KA 2AS0A 1WXXA 3MQKA 1J2BA 1KSLA 3DH3A 3U28A 3LWQA 3HAXA 1ZL3A 1XPIA 4LGTA 1Q7HA 1SQWA 3LWOA 3UAIA 1WXWA 1ZS7A 3D79A 2J5TA 1V9FA 2AB4A 4LABA 3HJYA 2Q07A 1T5YA 3HJWA 2I82A 2ISTA 1IT8A 1ZE2A 1SGVA 4DMGA
chains in the Genus database with same CATH superfamily
3M6VA 3LWRA 1R3FA 1ZBOA 3M6UA 3VSEA 1R3EA 1ZE1A 2CX0A 2KKUA 2AUSA 1IQ8A 1TE7A 2DP9A 1KSLA 3U28A 1ZL3A 1SQWA 1UOYA 1ZS7A 1WK2A 2Q07A 1ZE2A 3M6WA 4Q1TA 2CX1A 3LWPA 3LDFA 2ANEA 1KSKA 2E5OA 2AS0A 1V9KA 4CI2B 1J2BA 3DH3A 4LGTA 3LWOA 3UAIA 3LJCA 2J5TA 1SI7A 2Z0TA 3IUWA 1XNEA 2AB4A 4LABA 4CI3B 3HJWA 4DMGA 2CWWA 2EY4A 2FRXA 2P38A 2B78A 3LWVA 2HVYA 1PRZA 1IT7A 3MQKA 3HAXA 1XPIA 1Z2ZA 1SB7A 1WXWA 3M4XA 1T5YA 1KSVA 1K8WA 2J5VA 1SZWA 3C0KA 2APOA 2RFKA 3M65A 1QYUA 3ZV0C 1WXXA 4TZ4C 3LWQA 1Q7HA 1S04A 4CI1B 3D79A 1V9FA 3HJYA 2I82A 2ISTA 1IT8A 3M6XA 1SGVA
chains in the Genus database with same CATH topology
1KSVA 1K8WA 2CWWA 2CX1A 1R3FA 2J5VA 4Q1TA 1SZWA 3LWRA 2EY4A 3VSEA 1R3EA 2P38A 3C0KA 2CX0A 1ZE1A 3LDFA 2APOA 2B78A 3LWPA 2RFKA 3LWVA 2AUSA 2HVYA 1PRZA 1QYUA 1IQ8A 1KSKA 1IT7A 1V9KA 2AS0A 1WXXA 3MQKA 1J2BA 1KSLA 3DH3A 3U28A 3LWQA 3HAXA 1ZL3A 1XPIA 4LGTA 1Z2ZA 1Q7HA 1SQWA 1SB7A 3LWOA 3UAIA 1WXWA 1ZS7A 3D79A 2J5TA 1SI7A 1V9FA 2AB4A 4LABA 3HJYA 2Q07A 1T5YA 3HJWA 2I82A 2ISTA 1IT8A 1ZE2A 1SGVA 4DMGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KSV A;  1K8W A;  2CWW A;  2CX1 A;  1R3F A;  2J5V A;  4Q1T A;  3LWR A;  2EY4 A;  3VSE A;  1R3E A;  2P38 A;  3C0K A;  2CX0 A;  1ZE1 A;  3LDF A;  2APO A;  2B78 A;  3LWP A;  2RFK A;  3LWV A;  2AUS A;  2HVY A;  1PRZ A;  1QYU A;  1IQ8 A;  1KSK A;  1IT7 A;  1V9K A;  2AS0 A;  1WXX A;  3MQK A;  1J2B A;  1KSL A;  3DH3 A;  3U28 A;  3LWQ A;  3HAX A;  1ZL3 A;  1XPI A;  4LGT A;  1Q7H A;  1SQW A;  3LWO A;  3UAI A;  1WXW A;  1ZS7 A;  3D79 A;  2J5T A;  1V9F A;  2AB4 A;  4LAB A;  3HJY A;  2Q07 A;  1T5Y A;  3HJW A;  2I82 A;  2IST A;  1IT8 A;  1ZE2 A;  1SGV A;  4DMG A; 
#chains in the Genus database with same CATH topology
 3M6V A;  3LWR A;  1R3F A;  1ZBO A;  3M6U A;  3VSE A;  1R3E A;  1ZE1 A;  2CX0 A;  2KKU A;  2AUS A;  1IQ8 A;  1TE7 A;  2DP9 A;  1KSL A;  3U28 A;  1ZL3 A;  1SQW A;  1UOY A;  1ZS7 A;  1WK2 A;  2Q07 A;  1ZE2 A;  3M6W A;  4Q1T A;  2CX1 A;  3LWP A;  3LDF A;  2ANE A;  1KSK A;  2E5O A;  2AS0 A;  1V9K A;  4CI2 B;  1J2B A;  3DH3 A;  4LGT A;  3LWO A;  3UAI A;  3LJC A;  2J5T A;  1SI7 A;  2Z0T A;  3IUW A;  1XNE A;  2AB4 A;  4LAB A;  4CI3 B;  3HJW A;  4DMG A;  2CWW A;  2EY4 A;  2FRX A;  2P38 A;  2B78 A;  3LWV A;  2HVY A;  1PRZ A;  1IT7 A;  3MQK A;  3HAX A;  1XPI A;  1Z2Z A;  1SB7 A;  1WXW A;  3M4X A;  1T5Y A;  1KSV A;  1K8W A;  2J5V A;  1SZW A;  3C0K A;  2APO A;  2RFK A;  3M65 A;  1QYU A;  3ZV0 C;  1WXX A;  4TZ4 C;  3LWQ A;  1Q7H A;  1S04 A;  4CI1 B;  3D79 A;  1V9F A;  3HJY A;  2I82 A;  2IST A;  1IT8 A;  3M6X A;  1SGV A; 
#chains in the Genus database with same CATH homology
 1KSV A;  1K8W A;  2CWW A;  2CX1 A;  1R3F A;  2J5V A;  4Q1T A;  1SZW A;  3LWR A;  2EY4 A;  3VSE A;  1R3E A;  2P38 A;  3C0K A;  2CX0 A;  1ZE1 A;  3LDF A;  2APO A;  2B78 A;  3LWP A;  2RFK A;  3LWV A;  2AUS A;  2HVY A;  1PRZ A;  1QYU A;  1IQ8 A;  1KSK A;  1IT7 A;  1V9K A;  2AS0 A;  1WXX A;  3MQK A;  1J2B A;  1KSL A;  3DH3 A;  3U28 A;  3LWQ A;  3HAX A;  1ZL3 A;  1XPI A;  4LGT A;  1Z2Z A;  1Q7H A;  1SQW A;  1SB7 A;  3LWO A;  3UAI A;  1WXW A;  1ZS7 A;  3D79 A;  2J5T A;  1SI7 A;  1V9F A;  2AB4 A;  4LAB A;  3HJY A;  2Q07 A;  1T5Y A;  3HJW A;  2I82 A;  2IST A;  1IT8 A;  1ZE2 A;  1SGV A;  4DMG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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