3UALA

Crystal structure of 14-3-3 epsilon with mlf1 peptide
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
230
structure length
230
Chain Sequence
DREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights of the MLF1/14-3-3 interaction.
pubmed doi rcsb
molecule tags Signaling protein/protein binding
source organism Homo sapiens
molecule keywords 14-3-3 protein epsilon
total genus 110
structure length 230
sequence length 230
ec nomenclature
pdb deposition date 2011-10-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 3ualA00
4O46A 4N7GA 3P1QA 3RDHA 4DHQA 4DHRA 2BQ0A 4WRQA 4FR3A 3SMNA 2O98A 5LHOA 3UALA 5LU1A 5LVZA 4FL5A 3P1NA 3AXYC 4DHNA 2B05A 5BTVA 3U9XA 2BTPA 3M51A 4JC3A 5BY9A 5J31A 4IEAA 1O9EA 3SMOA 2C74A 2C1NA 1A4OA 3EFZA 3SMLA 4GNTA 1A37A 4DNKA 2C23A 4DHOA 3O8IA 3P1OA 2C63A 4DATA 4Y5IA 4DHUA 2C1JA 2BR9A 4JDDA 4DHSA 1YZ5A 1IB1A 5EXAA 1A38A 1QJBA 5D3EA 4QLIA 3LW1A 2NPMA 3P1PA 2WH0A 1QJAA 4Y3BA 5D2DA 3SMMA 1YWTA 4DHPA 3NKXA 4N84A 4Y32A 3IQJA 3UZDA 4BG6A 1O9FA 3SPRA 2O02A 3IQUA 3MHRA 4DAUA 2O8PA 4IHLA 3SP5A 3E6YA 1O9CA 5LX2A 4HKCA 4J6SA 4ZQ0A 5F74A 2V7DA 4DX0A 3IQVA 3SMKA 4DHTA 5EWZA 5D3FA 3UX0A 3CU8A 4N7YA 4DHMA 5HF3A 3P1SA 3P1RA 4FJ3A 3UBWA 3T0MA 4E2EA 3T0LA 1O9DA 3M50A 4F7RA 5IQPA 4ZDRA 5LU2A
chains in the Genus database with same CATH superfamily
4O46A 4N7GA 3P1QA 3RDHA 4DHQA 4DHRA 2BQ0A 4WRQA 4FR3A 3SMNA 2C9KA 4QX1A 2O98A 5LHOA 3UALA 5LU1A 5LVZA 4FL5A 3P1NA 3AXYC 4DHNA 2B05A 5BTVA 3U9XA 2BTPA 3M51A 4JC3A 5BY9A 5J31A 4IEAA 1O9EA 3SMOA 2C74A 2C1NA 1A4OA 1URJA 3EFZA 3SMLA 4GNTA 3CQCA 4QX3A 1A37A 4W8JA 4DNKA 2C23A 4DHOA 3O8IA 3P1OA 2C63A 4ARYA 4DATA 4Y5IA 4DHUA 1CIYA 4QX2A 2C1JA 2BR9A 3EB7A 4JDDA 4DHSA 3ZHEB 1YZ5A 1IB1A 5EXAA 1A38A 1QJBA 5D3EA 4QLIA 1JI6A 3LW1A 2NPMA 3P1PA 1DLCA 2WH0A 1QJAA 5D2DA 3SMMA 1YWTA 4MOAA 4DHPA 3NKXA 4N84A 4Y32A 3IQJA 3UZDA 4BG6A 1S2XA 1O9FA 3SPRA 2O02A 3CQGA 3IQUA 3MHRA 4DAUA 3X0UA 2O8PA 4IHLA 3SP5A 3E6YA 1O9CA 5LX2A 4HKCA 4J6SA 4ZQ0A 5F74A 2V7DA 4DX0A 4ZDRA 3IQVA 3SMKA 4DHTA 4QX0A 4ARXA 5EWZA 5D3FA 3UX0A 3CU8A 4N7YA 4DHMA 5HF3A 1W99A 3P1SA 3P1RA 3I4RA 4FJ3A 1I5PA 3UBWA 3T0MA 4E2EA 3T0LA 1O9DA 4D8MA 3M50A 4F7RA 5IQPA 4Y3BA 5LU2A
chains in the Genus database with same CATH topology
4O46A 4N7GA 3P1QA 3RDHA 4DHQA 4DHRA 2BQ0A 4WRQA 4FR3A 3SMNA 2O98A 5LHOA 3UALA 5LU1A 5LVZA 4FL5A 3P1NA 3AXYC 4DHNA 2B05A 5BTVA 3U9XA 2BTPA 3M51A 4JC3A 5BY9A 5J31A 4IEAA 1O9EA 3SMOA 2C74A 2C1NA 1A4OA 3EFZA 3SMLA 4GNTA 1A37A 4DNKA 2C23A 4DHOA 3O8IA 3P1OA 2C63A 4DATA 4Y5IA 4DHUA 2C1JA 2BR9A 4JDDA 4DHSA 1YZ5A 1IB1A 5EXAA 1A38A 1QJBA 5D3EA 4QLIA 3LW1A 2NPMA 3P1PA 2WH0A 1QJAA 4Y3BA 5D2DA 3SMMA 1YWTA 4DHPA 3NKXA 4N84A 4Y32A 3IQJA 3UZDA 4BG6A 1O9FA 3SPRA 2O02A 3IQUA 3MHRA 4DAUA 2O8PA 4IHLA 3SP5A 3E6YA 1O9CA 5LX2A 4HKCA 4J6SA 4ZQ0A 5F74A 2V7DA 4DX0A 3IQVA 3SMKA 4DHTA 5EWZA 5D3FA 3UX0A 3CU8A 4N7YA 4DHMA 5HF3A 3P1SA 3P1RA 4FJ3A 3UBWA 3T0MA 4E2EA 3T0LA 1O9DA 3M50A 4F7RA 5IQPA 4ZDRA 5LU2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O46 A;  4N7G A;  3P1Q A;  3RDH A;  4DHQ A;  4DHR A;  2BQ0 A;  4WRQ A;  4FR3 A;  3SMN A;  2O98 A;  5LHO A;  3UAL A;  5LU1 A;  5LVZ A;  4FL5 A;  3P1N A;  3AXY C;  4DHN A;  2B05 A;  5BTV A;  3U9X A;  2BTP A;  3M51 A;  4JC3 A;  5BY9 A;  5J31 A;  4IEA A;  1O9E A;  3SMO A;  2C74 A;  2C1N A;  1A4O A;  3EFZ A;  3SML A;  4GNT A;  1A37 A;  4DNK A;  2C23 A;  4DHO A;  3O8I A;  3P1O A;  2C63 A;  4DAT A;  4Y5I A;  4DHU A;  2C1J A;  2BR9 A;  4JDD A;  4DHS A;  1YZ5 A;  1IB1 A;  5EXA A;  1A38 A;  1QJB A;  5D3E A;  4QLI A;  3LW1 A;  2NPM A;  3P1P A;  2WH0 A;  1QJA A;  4Y3B A;  5D2D A;  3SMM A;  1YWT A;  4DHP A;  3NKX A;  4N84 A;  4Y32 A;  3IQJ A;  3UZD A;  4BG6 A;  1O9F A;  3SPR A;  2O02 A;  3IQU A;  3MHR A;  4DAU A;  2O8P A;  4IHL A;  3SP5 A;  3E6Y A;  1O9C A;  5LX2 A;  4HKC A;  4J6S A;  4ZQ0 A;  5F74 A;  2V7D A;  4DX0 A;  3IQV A;  3SMK A;  4DHT A;  5EWZ A;  5D3F A;  3UX0 A;  3CU8 A;  4N7Y A;  4DHM A;  5HF3 A;  3P1S A;  3P1R A;  4FJ3 A;  3UBW A;  3T0M A;  4E2E A;  3T0L A;  1O9D A;  3M50 A;  4F7R A;  5IQP A;  4ZDR A;  5LU2 A; 
#chains in the Genus database with same CATH topology
 4O46 A;  4N7G A;  3P1Q A;  3RDH A;  4DHQ A;  4DHR A;  2BQ0 A;  4WRQ A;  4FR3 A;  3SMN A;  2C9K A;  4QX1 A;  2O98 A;  5LHO A;  3UAL A;  5LU1 A;  5LVZ A;  4FL5 A;  3P1N A;  3AXY C;  4DHN A;  2B05 A;  5BTV A;  3U9X A;  2BTP A;  3M51 A;  4JC3 A;  5BY9 A;  5J31 A;  4IEA A;  1O9E A;  3SMO A;  2C74 A;  2C1N A;  1A4O A;  1URJ A;  3EFZ A;  3SML A;  4GNT A;  3CQC A;  4QX3 A;  1A37 A;  4W8J A;  4DNK A;  2C23 A;  4DHO A;  3O8I A;  3P1O A;  2C63 A;  4ARY A;  4DAT A;  4Y5I A;  4DHU A;  1CIY A;  4QX2 A;  2C1J A;  2BR9 A;  3EB7 A;  4JDD A;  4DHS A;  3ZHE B;  1YZ5 A;  1IB1 A;  5EXA A;  1A38 A;  1QJB A;  5D3E A;  4QLI A;  1JI6 A;  3LW1 A;  2NPM A;  3P1P A;  1DLC A;  2WH0 A;  1QJA A;  5D2D A;  3SMM A;  1YWT A;  4MOA A;  4DHP A;  3NKX A;  4N84 A;  4Y32 A;  3IQJ A;  3UZD A;  4BG6 A;  1S2X A;  1O9F A;  3SPR A;  2O02 A;  3CQG A;  3IQU A;  3MHR A;  4DAU A;  3X0U A;  2O8P A;  4IHL A;  3SP5 A;  3E6Y A;  1O9C A;  5LX2 A;  4HKC A;  4J6S A;  4ZQ0 A;  5F74 A;  2V7D A;  4DX0 A;  4ZDR A;  3IQV A;  3SMK A;  4DHT A;  4QX0 A;  4ARX A;  5EWZ A;  5D3F A;  3UX0 A;  3CU8 A;  4N7Y A;  4DHM A;  5HF3 A;  1W99 A;  3P1S A;  3P1R A;  3I4R A;  4FJ3 A;  1I5P A;  3UBW A;  3T0M A;  4E2E A;  3T0L A;  1O9D A;  4D8M A;  3M50 A;  4F7R A;  5IQP A;  4Y3B A;  5LU2 A; 
#chains in the Genus database with same CATH homology
 4O46 A;  4N7G A;  3P1Q A;  3RDH A;  4DHQ A;  4DHR A;  2BQ0 A;  4WRQ A;  4FR3 A;  3SMN A;  2O98 A;  5LHO A;  3UAL A;  5LU1 A;  5LVZ A;  4FL5 A;  3P1N A;  3AXY C;  4DHN A;  2B05 A;  5BTV A;  3U9X A;  2BTP A;  3M51 A;  4JC3 A;  5BY9 A;  5J31 A;  4IEA A;  1O9E A;  3SMO A;  2C74 A;  2C1N A;  1A4O A;  3EFZ A;  3SML A;  4GNT A;  1A37 A;  4DNK A;  2C23 A;  4DHO A;  3O8I A;  3P1O A;  2C63 A;  4DAT A;  4Y5I A;  4DHU A;  2C1J A;  2BR9 A;  4JDD A;  4DHS A;  1YZ5 A;  1IB1 A;  5EXA A;  1A38 A;  1QJB A;  5D3E A;  4QLI A;  3LW1 A;  2NPM A;  3P1P A;  2WH0 A;  1QJA A;  4Y3B A;  5D2D A;  3SMM A;  1YWT A;  4DHP A;  3NKX A;  4N84 A;  4Y32 A;  3IQJ A;  3UZD A;  4BG6 A;  1O9F A;  3SPR A;  2O02 A;  3IQU A;  3MHR A;  4DAU A;  2O8P A;  4IHL A;  3SP5 A;  3E6Y A;  1O9C A;  5LX2 A;  4HKC A;  4J6S A;  4ZQ0 A;  5F74 A;  2V7D A;  4DX0 A;  3IQV A;  3SMK A;  4DHT A;  5EWZ A;  5D3F A;  3UX0 A;  3CU8 A;  4N7Y A;  4DHM A;  5HF3 A;  3P1S A;  3P1R A;  4FJ3 A;  3UBW A;  3T0M A;  4E2E A;  3T0L A;  1O9D A;  3M50 A;  4F7R A;  5IQP A;  4ZDR A;  5LU2 A; 
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similar chains in the Genus database (?% sequence similarity)
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