3UNNA

Monomeric structure of the human mdc1 fha domain in complex with an mdc1 phospho-t4 peptide
Total Genus 22
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
108
structure length
108
Chain Sequence
SNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQELILFADLLCQYHRL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Mediator of DNA damage checkpoint protein 1
total genus 22
structure length 108
sequence length 108
ec nomenclature
pdb deposition date 2011-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 3unnA00
5DJOA 3VPYA 1UJXA 3ELVA 3FM8A 3UOTA 1FHQA 2PIEA 1LGQA 1K3JA 4G2SA 2EH0A 3UNNA 3KT9A 2W3OA 1J4LA 1LGPA 1K3QA 3UV0A 2JQIA 2JQLA 3VA4A 3UNMA 1FHRA 2FEZA 1G3GA 3ELSA 1K3NA 1DMZA 2AFFA 4D9VA 1K2NA 3I0MA 3UN0A 3MDBA 2FF4A 4JONA 2A0TA 1J4QA 3HUEA 4EGXA 1MZKA 1YJMA 4A0EA 1QU5A 3I0NA 3HUFA 1GXCA 3PO8A 3I6WA 2BRFA 2KB3A 1YJ5C 4EJQA 2LC1A 2JPEA 3OUNA 1WLNA 3HX1A 1WV3A 2CSWA 1R21A 3UMZA 1J4PA 1G6GA 4H87A 2JQJA 2XT9B 3I6UA 2G1LA 2KFUA 4QCJA 1K2MA 1J4KA 3GQSA 2JKDA 1UHTA 3POAA 5E50A 3VA1A 1J4OA 2KB4A 5A8IA 2KKLA
chains in the Genus database with same CATH superfamily
3GMJA 5DJOA 1Y3IA 4KU0D 3VPYA 1MR1A 3VZCA 1UJXA 3ELVA 3FM8A 3UOTA 1FHQA 2PIEA 1LGQA 1U7FB 2QVLA 1SUWA 1K3JA 5JERA 3V8PA 1DD1A 3DSHA 2JGRA 4G2SA 1U7VB 2EH0A 5DHPA 4WRRA 2AN1A 3UNNA 3KT9A 2W3OA 1MJSA 1J4LA 5DHQA 1LGPA 4HAOA 1K3QA 3UV0A 2JQIA 2JQLA 3V80A 4L02A 3VA4A 3V7YA 4DY6A 2P1RA 3UNMA 3V7WA 3PFNA 5JEJA 1FHRA 2FEZA 5DHSA 1G3GA 5A8IA 5EJHA 1QWTA 5JEOA 3AFOA 3ELSA 4JIVD 1DMZA 1K3NA 3V8NA 2AFFA 4D9VA 1K2NA 1YT5A 4V24A 2QV7A 3I0MA 5EJIA 3UN0A 5EJGA 3A77A 3V7UA 3MDBA 2FF4A 4JONA 3DITA 2I1WA 2A0TA 1J4QA 3HUEA 4EGXA 1KHXA 1YJMA 1MZKA 1QU5A 3I0NA 4A0EA 5JELA 3HUFA 1J2FA 1GXCA 4A4YA 1ZOQA 5BVIA 3PO8A 3I6WA 1MK2A 2BRFA 2KB3A 1YJ5C 1U0TA 4EJQA 2LC1A 2JPEA 3OUNA 5DHRA 3VZBA 1WLNA 3VZDA 3V8QA 3HX1A 1WV3A 2CSWA 1R21A 3UMZA 1J4PA 3S40A 1Z0ZA 1G6GA 5EJFA 5DHUA 2BONA 1YGSA 1U0RA 3T5PA 1U7FA 5DHTA 1Z0UA 1G88A 2I29A 4H87A 5C4VA 2JQJA 2XT9B 1DEVA 1U7VA 5JEMA 3I6UA 2Q5FA 5JEKA 1Y3HA 2G1LA 2KFUA 4QCJA 2I2CA 1K2MA 2XXSA 1J4KA 4R9PA 2I2AA 3GQSA 2I2BA 4JIWD 2JKDA 3V8MA 2I2DA 4WERA 1Z0SA 1UHTA 3POAA 5E50A 1KHUA 3VA1A 1J4OA 2KB4A 3V8RA 2KKLA 2I2FA
chains in the Genus database with same CATH topology
3GMJA 5DJOA 4KU0D 3VPYA 1MR1A 3VZCA 1UJXA 3ELVA 3FM8A 3UOTA 1FHQA 2PIEA 1LGQA 1U7FB 2QVLA 1K3JA 5JERA 1DD1A 3DSHA 2JGRA 4G2SA 1U7VB 2EH0A 4WRRA 3UNNA 3KT9A 2W3OA 1MJSA 1J4LA 1LGPA 1K3QA 3UV0A 2JQIA 2JQLA 4L02A 3VA4A 2P1RA 3UNMA 5JEJA 1FHRA 2FEZA 1G3GA 1QWTA 5JEOA 3ELSA 4JIVD 1DMZA 1K3NA 2AFFA 4D9VA 1K2NA 4V24A 2QV7A 3I0MA 3UN0A 3A77A 3MDBA 2FF4A 4JONA 3DITA 2A0TA 1J4QA 3HUEA 4EGXA 1KHXA 1YJMA 1MZKA 1QU5A 3I0NA 4A0EA 5JELA 3HUFA 1J2FA 1GXCA 4A4YA 1ZOQA 5BVIA 3PO8A 3I6WA 1MK2A 2BRFA 2KB3A 1YJ5C 4EJQA 2LC1A 2JPEA 3OUNA 3VZBA 1WLNA 3VZDA 3HX1A 1WV3A 2CSWA 1R21A 3UMZA 1J4PA 3S40A 1G6GA 2BONA 1YGSA 3T5PA 1U7FA 1G88A 4H87A 5C4VA 2JQJA 2XT9B 1DEVA 1U7VA 5JEMA 3I6UA 5JEKA 2G1LA 2KFUA 4QCJA 1K2MA 2XXSA 1J4KA 4R9PA 3GQSA 4JIWD 2JKDA 4WERA 1UHTA 3POAA 5E50A 1KHUA 3VA1A 1J4OA 2KB4A 5A8IA 2KKLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DJO A;  3VPY A;  1UJX A;  3ELV A;  3FM8 A;  3UOT A;  1FHQ A;  2PIE A;  1LGQ A;  1K3J A;  4G2S A;  2EH0 A;  3UNN A;  3KT9 A;  2W3O A;  1J4L A;  1LGP A;  1K3Q A;  3UV0 A;  2JQI A;  2JQL A;  3VA4 A;  3UNM A;  1FHR A;  2FEZ A;  1G3G A;  3ELS A;  1K3N A;  1DMZ A;  2AFF A;  4D9V A;  1K2N A;  3I0M A;  3UN0 A;  3MDB A;  2FF4 A;  4JON A;  2A0T A;  1J4Q A;  3HUE A;  4EGX A;  1MZK A;  1YJM A;  4A0E A;  1QU5 A;  3I0N A;  3HUF A;  1GXC A;  3PO8 A;  3I6W A;  2BRF A;  2KB3 A;  1YJ5 C;  4EJQ A;  2LC1 A;  2JPE A;  3OUN A;  1WLN A;  3HX1 A;  1WV3 A;  2CSW A;  1R21 A;  3UMZ A;  1J4P A;  1G6G A;  4H87 A;  2JQJ A;  2XT9 B;  3I6U A;  2G1L A;  2KFU A;  4QCJ A;  1K2M A;  1J4K A;  3GQS A;  2JKD A;  1UHT A;  3POA A;  5E50 A;  3VA1 A;  1J4O A;  2KB4 A;  5A8I A;  2KKL A; 
#chains in the Genus database with same CATH topology
 3GMJ A;  5DJO A;  1Y3I A;  4KU0 D;  3VPY A;  1MR1 A;  3VZC A;  1UJX A;  3ELV A;  3FM8 A;  3UOT A;  1FHQ A;  2PIE A;  1LGQ A;  1U7F B;  2QVL A;  1SUW A;  1K3J A;  5JER A;  3V8P A;  1DD1 A;  3DSH A;  2JGR A;  4G2S A;  1U7V B;  2EH0 A;  5DHP A;  4WRR A;  2AN1 A;  3UNN A;  3KT9 A;  2W3O A;  1MJS A;  1J4L A;  5DHQ A;  1LGP A;  4HAO A;  1K3Q A;  3UV0 A;  2JQI A;  2JQL A;  3V80 A;  4L02 A;  3VA4 A;  3V7Y A;  4DY6 A;  2P1R A;  3UNM A;  3V7W A;  3PFN A;  5JEJ A;  1FHR A;  2FEZ A;  5DHS A;  1G3G A;  5A8I A;  5EJH A;  1QWT A;  5JEO A;  3AFO A;  3ELS A;  4JIV D;  1DMZ A;  1K3N A;  3V8N A;  2AFF A;  4D9V A;  1K2N A;  1YT5 A;  4V24 A;  2QV7 A;  3I0M A;  5EJI A;  3UN0 A;  5EJG A;  3A77 A;  3V7U A;  3MDB A;  2FF4 A;  4JON A;  3DIT A;  2I1W A;  2A0T A;  1J4Q A;  3HUE A;  4EGX A;  1KHX A;  1YJM A;  1MZK A;  1QU5 A;  3I0N A;  4A0E A;  5JEL A;  3HUF A;  1J2F A;  1GXC A;  4A4Y A;  1ZOQ A;  5BVI A;  3PO8 A;  3I6W A;  1MK2 A;  2BRF A;  2KB3 A;  1YJ5 C;  1U0T A;  4EJQ A;  2LC1 A;  2JPE A;  3OUN A;  5DHR A;  3VZB A;  1WLN A;  3VZD A;  3V8Q A;  3HX1 A;  1WV3 A;  2CSW A;  1R21 A;  3UMZ A;  1J4P A;  3S40 A;  1Z0Z A;  1G6G A;  5EJF A;  5DHU A;  2BON A;  1YGS A;  1U0R A;  3T5P A;  1U7F A;  5DHT A;  1Z0U A;  1G88 A;  2I29 A;  4H87 A;  5C4V A;  2JQJ A;  2XT9 B;  1DEV A;  1U7V A;  5JEM A;  3I6U A;  2Q5F A;  5JEK A;  1Y3H A;  2G1L A;  2KFU A;  4QCJ A;  2I2C A;  1K2M A;  2XXS A;  1J4K A;  4R9P A;  2I2A A;  3GQS A;  2I2B A;  4JIW D;  2JKD A;  3V8M A;  2I2D A;  4WER A;  1Z0S A;  1UHT A;  3POA A;  5E50 A;  1KHU A;  3VA1 A;  1J4O A;  2KB4 A;  3V8R A;  2KKL A;  2I2F A; 
#chains in the Genus database with same CATH homology
 3GMJ A;  5DJO A;  4KU0 D;  3VPY A;  1MR1 A;  3VZC A;  1UJX A;  3ELV A;  3FM8 A;  3UOT A;  1FHQ A;  2PIE A;  1LGQ A;  1U7F B;  2QVL A;  1K3J A;  5JER A;  1DD1 A;  3DSH A;  2JGR A;  4G2S A;  1U7V B;  2EH0 A;  4WRR A;  3UNN A;  3KT9 A;  2W3O A;  1MJS A;  1J4L A;  1LGP A;  1K3Q A;  3UV0 A;  2JQI A;  2JQL A;  4L02 A;  3VA4 A;  2P1R A;  3UNM A;  5JEJ A;  1FHR A;  2FEZ A;  1G3G A;  1QWT A;  5JEO A;  3ELS A;  4JIV D;  1DMZ A;  1K3N A;  2AFF A;  4D9V A;  1K2N A;  4V24 A;  2QV7 A;  3I0M A;  3UN0 A;  3A77 A;  3MDB A;  2FF4 A;  4JON A;  3DIT A;  2A0T A;  1J4Q A;  3HUE A;  4EGX A;  1KHX A;  1YJM A;  1MZK A;  1QU5 A;  3I0N A;  4A0E A;  5JEL A;  3HUF A;  1J2F A;  1GXC A;  4A4Y A;  1ZOQ A;  5BVI A;  3PO8 A;  3I6W A;  1MK2 A;  2BRF A;  2KB3 A;  1YJ5 C;  4EJQ A;  2LC1 A;  2JPE A;  3OUN A;  3VZB A;  1WLN A;  3VZD A;  3HX1 A;  1WV3 A;  2CSW A;  1R21 A;  3UMZ A;  1J4P A;  3S40 A;  1G6G A;  2BON A;  1YGS A;  3T5P A;  1U7F A;  1G88 A;  4H87 A;  5C4V A;  2JQJ A;  2XT9 B;  1DEV A;  1U7V A;  5JEM A;  3I6U A;  5JEK A;  2G1L A;  2KFU A;  4QCJ A;  1K2M A;  2XXS A;  1J4K A;  4R9P A;  3GQS A;  4JIW D;  2JKD A;  4WER A;  1UHT A;  3POA A;  5E50 A;  1KHU A;  3VA1 A;  1J4O A;  2KB4 A;  5A8I A;  2KKL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...