3UXUA

The structure of the catalytic domain of the sulfolobus spindle-shaped viral integrase reveals an evolutionarily conserved catalytic core and supports a mechanism of dna cleavage in trans
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
159
structure length
159
Chain Sequence
IYIPTLEEIKRTLQLAKDYSENVYFIYRIALESGVRLSEVLKVLKEPERDICGNDVCYYPLSWTRGYKGVFYVFHITPLKRVEVTKWAIADFERRHKDAIAIKYFRKFVASKMAELSVPLDIIDFIQGRKPARVLTQHYVSLFGIAKEQYKKYAEWLKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structure of an Archaeal Viral Integrase Reveals an Evolutionarily Conserved Catalytic Core yet Supports a Mechanism of DNA Cleavage in trans.
pubmed doi rcsb
molecule keywords Probable integrase
molecule tags Recombination
source organism Sulfolobus virus 1
total genus 56
structure length 159
sequence length 159
ec nomenclature
pdb deposition date 2011-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16795 Phage_integr_3 Archaeal phage integrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.443.10 Mainly Alpha Orthogonal Bundle hpI Integrase; Chain A Intergrase catalytic core 3uxuA00
2HOIA 1Z19A 1KBUA 5CRXA 4DKSA 1PVQA 1P4EA 1AE9A 5DORA 5C6KA 1PVRA 1P7DA 2CRXA 1FLOA 1PVPA 1M6XC 3MGVA 2A3VA 3NKHA 1MA7A 1XO0A 4CRXA 1OUQA 3C28A 1NZBA 1A0PA 3CRXA 1CRXA 2HOFA 1AIHA 1DRGA 1Z1BA 1Q3UA 1F44A 3UXUA 1P4EC 3C29A 1M6XA 3VCFA 4A8EA 1XNSA 1Q3VA 5DCFA
chains in the Genus database with same CATH superfamily
2HOIA 3T79A 4F43A 1Z19A 1KBUA 5CRXA 4DKSA 4E0YA 1PVQA 1AE9A 1P4EA 5DORA 5C6KA 1PVRA 1P7DA 2CRXA 2V6EA 1FLOA 1PVPA 1M6XC 3MGVA 2A3VA 4E0JA 4ACOA 3NKHA 1MA7A 1XO0A 4CRXA 4E0GA 4E0PA 3SQIA 4DWPA 1OUQA 4F41A 3C28A 1NZBA 1A0PA 4E10A 3CRXA 1CRXA 2HOFA 1AIHA 1DRGA 1Z1BA 1Q3UA 1F44A 3UXUA 4E0ZA 1P4EC 3C29A 1M6XA 3VCFA 4A8EA 1XNSA 1Q3VA 5DCFA
chains in the Genus database with same CATH topology
2HOIA 1Z19A 1KBUA 5CRXA 4DKSA 1PVQA 1P4EA 1AE9A 5DORA 5C6KA 1PVRA 1P7DA 2CRXA 1FLOA 1PVPA 1M6XC 3MGVA 2A3VA 3NKHA 1MA7A 1XO0A 4CRXA 1OUQA 3C28A 1NZBA 1A0PA 3CRXA 1CRXA 2HOFA 1AIHA 1DRGA 1Z1BA 1Q3UA 1F44A 3UXUA 1P4EC 3C29A 1M6XA 3VCFA 4A8EA 1XNSA 1Q3VA 5DCFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HOI A;  1Z19 A;  1KBU A;  5CRX A;  4DKS A;  1PVQ A;  1P4E A;  1AE9 A;  5DOR A;  5C6K A;  1PVR A;  1P7D A;  2CRX A;  1FLO A;  1PVP A;  1M6X C;  3MGV A;  2A3V A;  3NKH A;  1MA7 A;  1XO0 A;  4CRX A;  1OUQ A;  3C28 A;  1NZB A;  1A0P A;  3CRX A;  1CRX A;  2HOF A;  1AIH A;  1DRG A;  1Z1B A;  1Q3U A;  1F44 A;  3UXU A;  1P4E C;  3C29 A;  1M6X A;  3VCF A;  4A8E A;  1XNS A;  1Q3V A;  5DCF A; 
#chains in the Genus database with same CATH topology
 2HOI A;  3T79 A;  4F43 A;  1Z19 A;  1KBU A;  5CRX A;  4DKS A;  4E0Y A;  1PVQ A;  1AE9 A;  1P4E A;  5DOR A;  5C6K A;  1PVR A;  1P7D A;  2CRX A;  2V6E A;  1FLO A;  1PVP A;  1M6X C;  3MGV A;  2A3V A;  4E0J A;  4ACO A;  3NKH A;  1MA7 A;  1XO0 A;  4CRX A;  4E0G A;  4E0P A;  3SQI A;  4DWP A;  1OUQ A;  4F41 A;  3C28 A;  1NZB A;  1A0P A;  4E10 A;  3CRX A;  1CRX A;  2HOF A;  1AIH A;  1DRG A;  1Z1B A;  1Q3U A;  1F44 A;  3UXU A;  4E0Z A;  1P4E C;  3C29 A;  1M6X A;  3VCF A;  4A8E A;  1XNS A;  1Q3V A;  5DCF A; 
#chains in the Genus database with same CATH homology
 2HOI A;  1Z19 A;  1KBU A;  5CRX A;  4DKS A;  1PVQ A;  1P4E A;  1AE9 A;  5DOR A;  5C6K A;  1PVR A;  1P7D A;  2CRX A;  1FLO A;  1PVP A;  1M6X C;  3MGV A;  2A3V A;  3NKH A;  1MA7 A;  1XO0 A;  4CRX A;  1OUQ A;  3C28 A;  1NZB A;  1A0P A;  3CRX A;  1CRX A;  2HOF A;  1AIH A;  1DRG A;  1Z1B A;  1Q3U A;  1F44 A;  3UXU A;  1P4E C;  3C29 A;  1M6X A;  3VCF A;  4A8E A;  1XNS A;  1Q3V A;  5DCF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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