3UXUA

The structure of the catalytic domain of the sulfolobus spindle-shaped viral integrase reveals an evolutionarily conserved catalytic core and supports a mechanism of dna cleavage in trans
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
159
structure length
159
Chain Sequence
IYIPTLEEIKRTLQLAKDYSENVYFIYRIALESGVRLSEVLKVLKEPERDICGNDVCYYPLSWTRGYKGVFYVFHITPLKRVEVTKWAIADFERRHKDAIAIKYFRKFVASKMAELSVPLDIIDFIQGRKPARVLTQHYVSLFGIAKEQYKKYAEWLKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structure of an Archaeal Viral Integrase Reveals an Evolutionarily Conserved Catalytic Core yet Supports a Mechanism of DNA Cleavage in trans.
pubmed doi rcsb
molecule tags Recombination
source organism Sulfolobus virus 1
molecule keywords Probable integrase
total genus 56
structure length 159
sequence length 159
ec nomenclature
pdb deposition date 2011-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16795 Phage_integr_3 Archaeal phage integrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.443.10 Mainly Alpha Orthogonal Bundle hpI Integrase; Chain A Intergrase catalytic core 3uxuA00
1PVPA 1F44A 1M6XC 1XO0A 3MGVA 5C6KA 1KBUA 4CRXA 1Z1BA 1XNSA 1AE9A 1OUQA 3NKHA 1DRGA 1AIHA 1CRXA 3C29A 4A8EA 1Z19A 1Q3UA 4DKSA 1P4EA 1Q3VA 3CRXA 3UXUA 1FLOA 1A0PA 1M6XA 5DCFA 5CRXA 2HOIA 1PVRA 3C28A 2A3VA 1MA7A 5DORA 1PVQA 1NZBA 2HOFA 3VCFA 1P7DA 1P4EC 2CRXA
chains in the Genus database with same CATH superfamily
1PVPA 1F44A 1M6XC 1XO0A 3MGVA 5C6KA 1KBUA 4CRXA 1Z1BA 4E0ZA 1XNSA 1AE9A 4E10A 1OUQA 3NKHA 1DRGA 1AIHA 2V6EA 3SQIA 1CRXA 3C29A 4A8EA 4E0GA 1Z19A 4DWPA 1Q3UA 4DKSA 3T79A 1Q3VA 1P4EA 3CRXA 3UXUA 1FLOA 1A0PA 1M6XA 4E0YA 5DCFA 5CRXA 2HOIA 1PVRA 3C28A 2A3VA 1MA7A 4ACOA 5DORA 4E0PA 1PVQA 4E0JA 4F43A 4F41A 1NZBA 3VCFA 2HOFA 1P7DA 1P4EC 2CRXA
chains in the Genus database with same CATH topology
1PVPA 1F44A 1M6XC 1XO0A 3MGVA 5C6KA 1KBUA 4CRXA 1Z1BA 1XNSA 1AE9A 1OUQA 3NKHA 1DRGA 1AIHA 1CRXA 3C29A 4A8EA 1Z19A 1Q3UA 4DKSA 1P4EA 1Q3VA 3CRXA 3UXUA 1FLOA 1A0PA 1M6XA 5DCFA 5CRXA 2HOIA 1PVRA 3C28A 2A3VA 1MA7A 5DORA 1PVQA 1NZBA 2HOFA 3VCFA 1P7DA 1P4EC 2CRXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PVP A;  1F44 A;  1M6X C;  1XO0 A;  3MGV A;  5C6K A;  1KBU A;  4CRX A;  1Z1B A;  1XNS A;  1AE9 A;  1OUQ A;  3NKH A;  1DRG A;  1AIH A;  1CRX A;  3C29 A;  4A8E A;  1Z19 A;  1Q3U A;  4DKS A;  1P4E A;  1Q3V A;  3CRX A;  3UXU A;  1FLO A;  1A0P A;  1M6X A;  5DCF A;  5CRX A;  2HOI A;  1PVR A;  3C28 A;  2A3V A;  1MA7 A;  5DOR A;  1PVQ A;  1NZB A;  2HOF A;  3VCF A;  1P7D A;  1P4E C;  2CRX A; 
#chains in the Genus database with same CATH topology
 1PVP A;  1F44 A;  1M6X C;  1XO0 A;  3MGV A;  5C6K A;  1KBU A;  4CRX A;  1Z1B A;  4E0Z A;  1XNS A;  1AE9 A;  4E10 A;  1OUQ A;  3NKH A;  1DRG A;  1AIH A;  2V6E A;  3SQI A;  1CRX A;  3C29 A;  4A8E A;  4E0G A;  1Z19 A;  4DWP A;  1Q3U A;  4DKS A;  3T79 A;  1Q3V A;  1P4E A;  3CRX A;  3UXU A;  1FLO A;  1A0P A;  1M6X A;  4E0Y A;  5DCF A;  5CRX A;  2HOI A;  1PVR A;  3C28 A;  2A3V A;  1MA7 A;  4ACO A;  5DOR A;  4E0P A;  1PVQ A;  4E0J A;  4F43 A;  4F41 A;  1NZB A;  3VCF A;  2HOF A;  1P7D A;  1P4E C;  2CRX A; 
#chains in the Genus database with same CATH homology
 1PVP A;  1F44 A;  1M6X C;  1XO0 A;  3MGV A;  5C6K A;  1KBU A;  4CRX A;  1Z1B A;  1XNS A;  1AE9 A;  1OUQ A;  3NKH A;  1DRG A;  1AIH A;  1CRX A;  3C29 A;  4A8E A;  1Z19 A;  1Q3U A;  4DKS A;  1P4E A;  1Q3V A;  3CRX A;  3UXU A;  1FLO A;  1A0P A;  1M6X A;  5DCF A;  5CRX A;  2HOI A;  1PVR A;  3C28 A;  2A3V A;  1MA7 A;  5DOR A;  1PVQ A;  1NZB A;  2HOF A;  3VCF A;  1P7D A;  1P4E C;  2CRX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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