3V45A

Crystal structure of de novo designed serine hydrolase osh55, northeast structural genomics consortium target or130
Total Genus 56
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
166
structure length
166
Chain Sequence
ARIREVQGDITEFQGDAIVNAANNYLKLGAGVAGAILRKGGPSIQEECDRIGKIRVGEAAVTGAGNLPVRYVIHAAVLGDEPASLETVRKATKSALEKAVELGLKTVAFTALGAWVGGLPAEAVLRVMLEEIKKAPDTLEVTGVHGTEKSAEAARRALLEHHHHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Design of activated serine-containing catalytic triads with atomic-level accuracy.
pubmed doi rcsb
molecule tags De novo protein
molecule keywords Serine hydrolase OSH55
total genus 56
structure length 166
sequence length 166
ec nomenclature
pdb deposition date 2011-12-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3v45A00
1ZR3A 3SIGA 3V2BA 3Q71A 3GQOA 2AFCA 5AILA 3IIDA 4D86A 4R6TA 3IIFA 3EWRA 3H8EA 4ETKA 1HJZA 5D8NA 3SIHA 4K3NA 3EWOA 4ZY0A 4ESSA 3EJGA 2X47A 4ETJA 3ETIA 2XD7A 2LGRA 3EKEA 4K0CA 1LCPA 4JLLA 4TU0A 4R76A 2EWBA 5E3BA 1BPNA 5FSYA 1BLLE 4JCAA 5FSZA 4ZY1A 2FG1A 4ZY2A 5CB5A 4ABKA 3GQEA 4X2TA 5CMSA 3SIJA 4ZYQA 2FXKA 3JZTA 4GVWA 3Q6ZA 4R7MA 4J5RA 2BFRA 4JGKA 1LAPA 3GPGA 1ZR5A 5HIHA 1YD9A 4J4ZA 3GPQA 4KYBA 4GUAA 2BFQA 3KQZA 3EW5A 1BPMA 1GYTA 2FAVA 3GPOA 2ACFA 2DX6A 4UMLA 5FSVA 5FSXA 3H8FA 3KQXA 1NJRA 3EWPA 3EWQA 4ZI6A 2EEEA 5DUSA 3SIIA 5CB3A 1LAMA 5FSUA 3KZWA 3IJ3A 3H8GA 3EJFA 4J5QA 3KR4A 4ZX8A 3T8WA 3V45A 4GVVA 3PEIA 4IQYA 4ABLA 1SPVA 4ZX9A 2J9AA 4JVVA 4J5SA 1VHUA 1TXZA 1TY8A 5CBMA 3JRUA 2L8RA 1LANA 5HOLA 2VRIA 3KR5A 3VFQA 4KSIA
chains in the Genus database with same CATH superfamily
1ZR3A 3SIGA 3V2BA 3Q71A 3GQOA 2AFCA 5AILA 3IIDA 4D86A 4R6TA 3IIFA 3EWRA 3H8EA 4ETKA 1HJZA 5D8NA 3SIHA 4K3NA 3EWOA 4ZY0A 4ESSA 3EJGA 2X47A 4ETJA 3ETIA 2XD7A 2LGRA 3EKEA 4K0CA 2KQVA 2RNKA 1LCPA 4JLLA 4TU0A 4R76A 2EWBA 5E3BA 1BPNA 5FSYA 1BLLE 4JCAA 5FSZA 4ZY1A 2FG1A 4ZY2A 5CB5A 4ABKA 3GQEA 4X2TA 5CMSA 3SIJA 4ZYQA 2FXKA 3JZTA 4GVWA 3Q6ZA 4R7MA 2WCTA 4J5RA 2BFRA 4JGKA 1LAPA 3GPGA 1ZR5A 5HIHA 1YD9A 4J4ZA 3GPQA 4KYBA 4GUAA 2BFQA 3KQZA 3EW5A 1BPMA 1GYTA 2FAVA 3GPOA 2W2GA 2ACFA 2DX6A 4UMLA 5FSVA 5FSXA 3H8FA 3KQXA 1NJRA 3EWPA 3EWQA 4ZI6A 2EEEA 5DUSA 3SIIA 5CB3A 1LAMA 2JZEA 5FSUA 3KZWA 3IJ3A 2JZFA 3H8GA 3EJFA 4J5QA 3KR4A 4ZX8A 3T8WA 3V45A 4GVVA 3PEIA 4IQYA 4ABLA 1SPVA 4ZX9A 2J9AA 4JVVA 4J5SA 1VHUA 1TXZA 1TY8A 2JZDA 5CBMA 3JRUA 2L8RA 1LANA 5HOLA 2VRIA 3KR5A 3VFQA 4KSIA
chains in the Genus database with same CATH topology
1ZR3A 3SIGA 3V2BA 3Q71A 3GQOA 2AFCA 5AILA 3IIDA 4D86A 4R6TA 3IIFA 3EWRA 3H8EA 4ETKA 1HJZA 5D8NA 3SIHA 4K3NA 3EWOA 4ZY0A 4ESSA 3EJGA 2X47A 4ETJA 3ETIA 2XD7A 2LGRA 3EKEA 4K0CA 1LCPA 4JLLA 4TU0A 4R76A 2EWBA 5E3BA 1BPNA 5FSYA 1BLLE 4JCAA 5FSZA 4ZY1A 2FG1A 4ZY2A 5CB5A 4ABKA 3GQEA 4X2TA 5CMSA 3SIJA 4ZYQA 2FXKA 3JZTA 4GVWA 3Q6ZA 4R7MA 4J5RA 2BFRA 4JGKA 1LAPA 3GPGA 1ZR5A 5HIHA 1YD9A 4J4ZA 3GPQA 4KYBA 4GUAA 2BFQA 3KQZA 3EW5A 1BPMA 1GYTA 2FAVA 3GPOA 2ACFA 2DX6A 4UMLA 5FSVA 5FSXA 3H8FA 3KQXA 1NJRA 3EWPA 3EWQA 4ZI6A 2EEEA 5DUSA 3SIIA 5CB3A 1LAMA 5FSUA 3KZWA 3IJ3A 3H8GA 3EJFA 4J5QA 3KR4A 4ZX8A 3T8WA 3V45A 4GVVA 3PEIA 4IQYA 4ABLA 1SPVA 4ZX9A 2J9AA 4JVVA 4J5SA 1VHUA 1TXZA 1TY8A 5CBMA 3JRUA 2L8RA 1LANA 5HOLA 2VRIA 3KR5A 3VFQA 4KSIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZR3 A;  3SIG A;  3V2B A;  3Q71 A;  3GQO A;  2AFC A;  5AIL A;  3IID A;  4D86 A;  4R6T A;  3IIF A;  3EWR A;  3H8E A;  4ETK A;  1HJZ A;  5D8N A;  3SIH A;  4K3N A;  3EWO A;  4ZY0 A;  4ESS A;  3EJG A;  2X47 A;  4ETJ A;  3ETI A;  2XD7 A;  2LGR A;  3EKE A;  4K0C A;  1LCP A;  4JLL A;  4TU0 A;  4R76 A;  2EWB A;  5E3B A;  1BPN A;  5FSY A;  1BLL E;  4JCA A;  5FSZ A;  4ZY1 A;  2FG1 A;  4ZY2 A;  5CB5 A;  4ABK A;  3GQE A;  4X2T A;  5CMS A;  3SIJ A;  4ZYQ A;  2FXK A;  3JZT A;  4GVW A;  3Q6Z A;  4R7M A;  4J5R A;  2BFR A;  4JGK A;  1LAP A;  3GPG A;  1ZR5 A;  5HIH A;  1YD9 A;  4J4Z A;  3GPQ A;  4KYB A;  4GUA A;  2BFQ A;  3KQZ A;  3EW5 A;  1BPM A;  1GYT A;  2FAV A;  3GPO A;  2ACF A;  2DX6 A;  4UML A;  5FSV A;  5FSX A;  3H8F A;  3KQX A;  1NJR A;  3EWP A;  3EWQ A;  4ZI6 A;  2EEE A;  5DUS A;  3SII A;  5CB3 A;  1LAM A;  5FSU A;  3KZW A;  3IJ3 A;  3H8G A;  3EJF A;  4J5Q A;  3KR4 A;  4ZX8 A;  3T8W A;  3V45 A;  4GVV A;  3PEI A;  4IQY A;  4ABL A;  1SPV A;  4ZX9 A;  2J9A A;  4JVV A;  4J5S A;  1VHU A;  1TXZ A;  1TY8 A;  5CBM A;  3JRU A;  2L8R A;  1LAN A;  5HOL A;  2VRI A;  3KR5 A;  3VFQ A;  4KSI A; 
#chains in the Genus database with same CATH topology
 1ZR3 A;  3SIG A;  3V2B A;  3Q71 A;  3GQO A;  2AFC A;  5AIL A;  3IID A;  4D86 A;  4R6T A;  3IIF A;  3EWR A;  3H8E A;  4ETK A;  1HJZ A;  5D8N A;  3SIH A;  4K3N A;  3EWO A;  4ZY0 A;  4ESS A;  3EJG A;  2X47 A;  4ETJ A;  3ETI A;  2XD7 A;  2LGR A;  3EKE A;  4K0C A;  2KQV A;  2RNK A;  1LCP A;  4JLL A;  4TU0 A;  4R76 A;  2EWB A;  5E3B A;  1BPN A;  5FSY A;  1BLL E;  4JCA A;  5FSZ A;  4ZY1 A;  2FG1 A;  4ZY2 A;  5CB5 A;  4ABK A;  3GQE A;  4X2T A;  5CMS A;  3SIJ A;  4ZYQ A;  2FXK A;  3JZT A;  4GVW A;  3Q6Z A;  4R7M A;  2WCT A;  4J5R A;  2BFR A;  4JGK A;  1LAP A;  3GPG A;  1ZR5 A;  5HIH A;  1YD9 A;  4J4Z A;  3GPQ A;  4KYB A;  4GUA A;  2BFQ A;  3KQZ A;  3EW5 A;  1BPM A;  1GYT A;  2FAV A;  3GPO A;  2W2G A;  2ACF A;  2DX6 A;  4UML A;  5FSV A;  5FSX A;  3H8F A;  3KQX A;  1NJR A;  3EWP A;  3EWQ A;  4ZI6 A;  2EEE A;  5DUS A;  3SII A;  5CB3 A;  1LAM A;  2JZE A;  5FSU A;  3KZW A;  3IJ3 A;  2JZF A;  3H8G A;  3EJF A;  4J5Q A;  3KR4 A;  4ZX8 A;  3T8W A;  3V45 A;  4GVV A;  3PEI A;  4IQY A;  4ABL A;  1SPV A;  4ZX9 A;  2J9A A;  4JVV A;  4J5S A;  1VHU A;  1TXZ A;  1TY8 A;  2JZD A;  5CBM A;  3JRU A;  2L8R A;  1LAN A;  5HOL A;  2VRI A;  3KR5 A;  3VFQ A;  4KSI A; 
#chains in the Genus database with same CATH homology
 1ZR3 A;  3SIG A;  3V2B A;  3Q71 A;  3GQO A;  2AFC A;  5AIL A;  3IID A;  4D86 A;  4R6T A;  3IIF A;  3EWR A;  3H8E A;  4ETK A;  1HJZ A;  5D8N A;  3SIH A;  4K3N A;  3EWO A;  4ZY0 A;  4ESS A;  3EJG A;  2X47 A;  4ETJ A;  3ETI A;  2XD7 A;  2LGR A;  3EKE A;  4K0C A;  1LCP A;  4JLL A;  4TU0 A;  4R76 A;  2EWB A;  5E3B A;  1BPN A;  5FSY A;  1BLL E;  4JCA A;  5FSZ A;  4ZY1 A;  2FG1 A;  4ZY2 A;  5CB5 A;  4ABK A;  3GQE A;  4X2T A;  5CMS A;  3SIJ A;  4ZYQ A;  2FXK A;  3JZT A;  4GVW A;  3Q6Z A;  4R7M A;  4J5R A;  2BFR A;  4JGK A;  1LAP A;  3GPG A;  1ZR5 A;  5HIH A;  1YD9 A;  4J4Z A;  3GPQ A;  4KYB A;  4GUA A;  2BFQ A;  3KQZ A;  3EW5 A;  1BPM A;  1GYT A;  2FAV A;  3GPO A;  2ACF A;  2DX6 A;  4UML A;  5FSV A;  5FSX A;  3H8F A;  3KQX A;  1NJR A;  3EWP A;  3EWQ A;  4ZI6 A;  2EEE A;  5DUS A;  3SII A;  5CB3 A;  1LAM A;  5FSU A;  3KZW A;  3IJ3 A;  3H8G A;  3EJF A;  4J5Q A;  3KR4 A;  4ZX8 A;  3T8W A;  3V45 A;  4GVV A;  3PEI A;  4IQY A;  4ABL A;  1SPV A;  4ZX9 A;  2J9A A;  4JVV A;  4J5S A;  1VHU A;  1TXZ A;  1TY8 A;  5CBM A;  3JRU A;  2L8R A;  1LAN A;  5HOL A;  2VRI A;  3KR5 A;  3VFQ A;  4KSI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...