3VFQA

Human parp14 (artd8, bal2) - macro domains 1 and 2 in complex with adenosine-5-diphosphoribose
Total Genus 122
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
401
structure length
375
Chain Sequence
KCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVFKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Poly [ADP-ribose] polymerase 14
total genus 122
structure length 375
sequence length 401
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3vfqA02
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 3vfqA01
2LGRA 3KQXA 4GVWA 4ABLA 4J5SA 3EJGA 3EWOA 5HIHA 3V2BA 2FAVA 5D8NA 5HOLA 3SIIA 3KR4A 4JCAA 2AFCA 4JLLA 4X2TA 3JZTA 4ABKA 1NJRA 1BLLE 5CB3A 2BFRA 4J4ZA 3JRUA 1TXZA 3ETIA 4IQYA 2L8RA 3EWRA 3SIHA 1BPMA 1SPVA 2FXKA 3Q71A 2DX6A 5CMSA 3GPQA 2EWBA 3Q6ZA 4ZYQA 3IIFA 4ZX9A 3PEIA 4ETJA 3GQEA 2X47A 4ETKA 4ESSA 4TU0A 5E3BA 4K0CA 4KYBA 4R76A 4ZY0A 3VFQA 4UMLA 4ZY2A 5FSXA 3GQOA 2EEEA 3EW5A 5FSVA 3EWPA 2J9AA 4R7MA 4R6TA 4J5RA 3SIGA 1HJZA 1GYTA 5FSUA 3KZWA 3IJ3A 4KSIA 4GVVA 3EWQA 3GPGA 3V45A 4J5QA 3EJFA 5CBMA 1LANA 1LAPA 1VHUA 3IIDA 4D86A 2ACFA 4GUAA 1LCPA 2VRIA 4ZI6A 3SIJA 3GPOA 5DUSA 1LAMA 3EKEA 4JGKA 3H8GA 4K3NA 2XD7A 5AILA 5CB5A 1TY8A 1BPNA 4ZX8A 4ZY1A 1ZR5A 3KR5A 3H8EA 5FSYA 2BFQA 5FSZA 3H8FA 1YD9A 2FG1A 3KQZA 4JVVA 3T8WA 1ZR3A
chains in the Genus database with same CATH superfamily
2LGRA 3KQXA 4GVWA 4ABLA 4J5SA 3EJGA 3EWOA 5HIHA 3V2BA 2FAVA 5D8NA 5HOLA 3SIIA 3KR4A 4JCAA 2AFCA 4JLLA 4X2TA 3JZTA 4ABKA 1NJRA 1BLLE 5CB3A 2BFRA 4J4ZA 3JRUA 1TXZA 3ETIA 4IQYA 2L8RA 3EWRA 3SIHA 1BPMA 1SPVA 2FXKA 3Q71A 2DX6A 5CMSA 3GPQA 2EWBA 3Q6ZA 4ZYQA 3IIFA 4ZX9A 2JZEA 3PEIA 4ETJA 3GQEA 2X47A 4ETKA 4ESSA 4TU0A 5E3BA 4K0CA 4KYBA 4R76A 4ZY0A 2WCTA 3VFQA 4UMLA 4ZY2A 5FSXA 3GQOA 2EEEA 3EW5A 5FSVA 3EWPA 2J9AA 4R7MA 4R6TA 4J5RA 3SIGA 1HJZA 1GYTA 5FSUA 3KZWA 3IJ3A 4KSIA 4GVVA 3EWQA 3GPGA 3V45A 4J5QA 2JZDA 3EJFA 5CBMA 2KQVA 1LANA 1LAPA 2JZFA 1VHUA 3IIDA 4D86A 2ACFA 4GUAA 1LCPA 2VRIA 4ZI6A 3SIJA 3GPOA 5DUSA 1LAMA 3EKEA 4JGKA 3H8GA 4K3NA 2XD7A 5AILA 2RNKA 5CB5A 1TY8A 1BPNA 4ZX8A 4ZY1A 1ZR5A 3KR5A 3H8EA 2W2GA 5FSYA 2BFQA 5FSZA 3H8FA 1YD9A 2FG1A 3KQZA 4JVVA 3T8WA 1ZR3A
chains in the Genus database with same CATH topology
2LGRA 3KQXA 4GVWA 4ABLA 4J5SA 3EJGA 3EWOA 5HIHA 3V2BA 2FAVA 5D8NA 5HOLA 3SIIA 3KR4A 4JCAA 2AFCA 4JLLA 4X2TA 3JZTA 4ABKA 1NJRA 1BLLE 5CB3A 2BFRA 4J4ZA 3JRUA 1TXZA 3ETIA 4IQYA 2L8RA 3EWRA 3SIHA 1BPMA 1SPVA 2FXKA 3Q71A 2DX6A 5CMSA 3GPQA 2EWBA 3Q6ZA 4ZYQA 3IIFA 4ZX9A 3PEIA 4ETJA 3GQEA 2X47A 4ETKA 4ESSA 4TU0A 5E3BA 4K0CA 4KYBA 4R76A 4ZY0A 3VFQA 4UMLA 4ZY2A 5FSXA 3GQOA 2EEEA 3EW5A 5FSVA 3EWPA 2J9AA 4R7MA 4R6TA 4J5RA 3SIGA 1HJZA 1GYTA 5FSUA 3KZWA 3IJ3A 4KSIA 4GVVA 3EWQA 3GPGA 3V45A 4J5QA 3EJFA 5CBMA 1LANA 1LAPA 1VHUA 3IIDA 4D86A 2ACFA 4GUAA 1LCPA 2VRIA 4ZI6A 3SIJA 3GPOA 5DUSA 1LAMA 3EKEA 4JGKA 3H8GA 4K3NA 2XD7A 5AILA 5CB5A 1TY8A 1BPNA 4ZX8A 4ZY1A 1ZR5A 3KR5A 3H8EA 5FSYA 2BFQA 5FSZA 3H8FA 1YD9A 2FG1A 3KQZA 4JVVA 3T8WA 1ZR3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LGR A;  3KQX A;  4GVW A;  4ABL A;  4J5S A;  3EJG A;  3EWO A;  5HIH A;  3V2B A;  2FAV A;  5D8N A;  5HOL A;  3SII A;  3KR4 A;  4JCA A;  2AFC A;  4JLL A;  4X2T A;  3JZT A;  4ABK A;  1NJR A;  1BLL E;  5CB3 A;  2BFR A;  4J4Z A;  3JRU A;  1TXZ A;  3ETI A;  4IQY A;  2L8R A;  3EWR A;  3SIH A;  1BPM A;  1SPV A;  2FXK A;  3Q71 A;  2DX6 A;  5CMS A;  3GPQ A;  2EWB A;  3Q6Z A;  4ZYQ A;  3IIF A;  4ZX9 A;  3PEI A;  4ETJ A;  3GQE A;  2X47 A;  4ETK A;  4ESS A;  4TU0 A;  5E3B A;  4K0C A;  4KYB A;  4R76 A;  4ZY0 A;  3VFQ A;  4UML A;  4ZY2 A;  5FSX A;  3GQO A;  2EEE A;  3EW5 A;  5FSV A;  3EWP A;  2J9A A;  4R7M A;  4R6T A;  4J5R A;  3SIG A;  1HJZ A;  1GYT A;  5FSU A;  3KZW A;  3IJ3 A;  4KSI A;  4GVV A;  3EWQ A;  3GPG A;  3V45 A;  4J5Q A;  3EJF A;  5CBM A;  1LAN A;  1LAP A;  1VHU A;  3IID A;  4D86 A;  2ACF A;  4GUA A;  1LCP A;  2VRI A;  4ZI6 A;  3SIJ A;  3GPO A;  5DUS A;  1LAM A;  3EKE A;  4JGK A;  3H8G A;  4K3N A;  2XD7 A;  5AIL A;  5CB5 A;  1TY8 A;  1BPN A;  4ZX8 A;  4ZY1 A;  1ZR5 A;  3KR5 A;  3H8E A;  5FSY A;  2BFQ A;  5FSZ A;  3H8F A;  1YD9 A;  2FG1 A;  3KQZ A;  4JVV A;  3T8W A;  1ZR3 A; 
#chains in the Genus database with same CATH topology
 2LGR A;  3KQX A;  4GVW A;  4ABL A;  4J5S A;  3EJG A;  3EWO A;  5HIH A;  3V2B A;  2FAV A;  5D8N A;  5HOL A;  3SII A;  3KR4 A;  4JCA A;  2AFC A;  4JLL A;  4X2T A;  3JZT A;  4ABK A;  1NJR A;  1BLL E;  5CB3 A;  2BFR A;  4J4Z A;  3JRU A;  1TXZ A;  3ETI A;  4IQY A;  2L8R A;  3EWR A;  3SIH A;  1BPM A;  1SPV A;  2FXK A;  3Q71 A;  2DX6 A;  5CMS A;  3GPQ A;  2EWB A;  3Q6Z A;  4ZYQ A;  3IIF A;  4ZX9 A;  2JZE A;  3PEI A;  4ETJ A;  3GQE A;  2X47 A;  4ETK A;  4ESS A;  4TU0 A;  5E3B A;  4K0C A;  4KYB A;  4R76 A;  4ZY0 A;  2WCT A;  3VFQ A;  4UML A;  4ZY2 A;  5FSX A;  3GQO A;  2EEE A;  3EW5 A;  5FSV A;  3EWP A;  2J9A A;  4R7M A;  4R6T A;  4J5R A;  3SIG A;  1HJZ A;  1GYT A;  5FSU A;  3KZW A;  3IJ3 A;  4KSI A;  4GVV A;  3EWQ A;  3GPG A;  3V45 A;  4J5Q A;  2JZD A;  3EJF A;  5CBM A;  2KQV A;  1LAN A;  1LAP A;  2JZF A;  1VHU A;  3IID A;  4D86 A;  2ACF A;  4GUA A;  1LCP A;  2VRI A;  4ZI6 A;  3SIJ A;  3GPO A;  5DUS A;  1LAM A;  3EKE A;  4JGK A;  3H8G A;  4K3N A;  2XD7 A;  5AIL A;  2RNK A;  5CB5 A;  1TY8 A;  1BPN A;  4ZX8 A;  4ZY1 A;  1ZR5 A;  3KR5 A;  3H8E A;  2W2G A;  5FSY A;  2BFQ A;  5FSZ A;  3H8F A;  1YD9 A;  2FG1 A;  3KQZ A;  4JVV A;  3T8W A;  1ZR3 A; 
#chains in the Genus database with same CATH homology
 2LGR A;  3KQX A;  4GVW A;  4ABL A;  4J5S A;  3EJG A;  3EWO A;  5HIH A;  3V2B A;  2FAV A;  5D8N A;  5HOL A;  3SII A;  3KR4 A;  4JCA A;  2AFC A;  4JLL A;  4X2T A;  3JZT A;  4ABK A;  1NJR A;  1BLL E;  5CB3 A;  2BFR A;  4J4Z A;  3JRU A;  1TXZ A;  3ETI A;  4IQY A;  2L8R A;  3EWR A;  3SIH A;  1BPM A;  1SPV A;  2FXK A;  3Q71 A;  2DX6 A;  5CMS A;  3GPQ A;  2EWB A;  3Q6Z A;  4ZYQ A;  3IIF A;  4ZX9 A;  3PEI A;  4ETJ A;  3GQE A;  2X47 A;  4ETK A;  4ESS A;  4TU0 A;  5E3B A;  4K0C A;  4KYB A;  4R76 A;  4ZY0 A;  3VFQ A;  4UML A;  4ZY2 A;  5FSX A;  3GQO A;  2EEE A;  3EW5 A;  5FSV A;  3EWP A;  2J9A A;  4R7M A;  4R6T A;  4J5R A;  3SIG A;  1HJZ A;  1GYT A;  5FSU A;  3KZW A;  3IJ3 A;  4KSI A;  4GVV A;  3EWQ A;  3GPG A;  3V45 A;  4J5Q A;  3EJF A;  5CBM A;  1LAN A;  1LAP A;  1VHU A;  3IID A;  4D86 A;  2ACF A;  4GUA A;  1LCP A;  2VRI A;  4ZI6 A;  3SIJ A;  3GPO A;  5DUS A;  1LAM A;  3EKE A;  4JGK A;  3H8G A;  4K3N A;  2XD7 A;  5AIL A;  5CB5 A;  1TY8 A;  1BPN A;  4ZX8 A;  4ZY1 A;  1ZR5 A;  3KR5 A;  3H8E A;  5FSY A;  2BFQ A;  5FSZ A;  3H8F A;  1YD9 A;  2FG1 A;  3KQZ A;  4JVV A;  3T8W A;  1ZR3 A; 
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