3VJ8A

Crystal structure of the human squalene synthase
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
335
structure length
335
Chain Sequence
SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 144
structure length 335
sequence length 335
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2011-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3vj8A00
4QXSF 5IVGA 3DYHA 3M9UA 3RYWA 3KRCB 3LVSA 4OMGA 5DW7A 5IM1A 2I19A 5ER8A 2F92F 2OPMA 3ASXA 4LOBA 3KRAA 3WEHA 4EA0A 4KQ5A 1YYTA 3WEJA 1VG3A 2PS8A 1WL3A 3WCJA 5EROA 3WSAA 3SDVA 3MZVA 1N1BA 4LLSA 1JFAA 4XQSF 2E8TA 3M00A 5DJRF 3NPKA 3TFPA 5EAUA 4RXAA 4EA2A 4Q23A 1V4KA 1WL2A 5ILJA 3KRCA 4DWBA 4KFAA 4XQTF 2AETA 3G4FA 1RTRA 3KRPB 5DHKA 4OKMA 5IKHA 3N3LF 2AELA 4OGUA 5E8HA 3DYFA 5AYPA 2ZEVA 4N1ZF 4GA3A 2OA6A 5DGSF 3P8RA 5JUZF 4FP4A 4NKFA 5IMNA 3TFVA 3PYBA 3VJ8A 3CC9A 2ZCOA 3UCAA 5JV2F 3BNYA 3QQVA 2Z4YA 4DEMF 3SDUA 3N3DA 5HN8A 1N24A 2QISA 3KRPA 3LEEA 3N1VF 2F7MF 3EZ3A 1WY0A 4JVJF 2FTZA 3LSNA 3WJNA 4KQSA 2E4OA 2F9KF 3QKCA 2E8UA 3ID0A 3WE9A 3WEKA 1YJ4A 3LJIA 3VJBA 3WC9A 4GP1A 5B0IA 2AZJA 2J5CA 4KWDA 3ZMCA 1HXGA 3KB9A 3CP6A 1HM7A 3OABB 4HD1A 4KKMA 1WL1A 4NFJF 3LOMA 5JV0F 1YYUA 3ZOUA 5IK0A 5CG6A 1V4EA 1EZFA 5ILYA 4WK5A 1YV5A 1HXCA 3V1XA 4LA5A 3WCFA 2PS4A 4ZQ8A 1HX9A 4GAXA 1UBXA 2F8CF 2F89F 3WCBA 4RXDA 3LMDA 5ILIA 3B7LA 1VG4A 4LXWA 3OABA 4NFIF 1N21A 1YYRA 1WL0A 3PH7A 5IL3A 5AFXA 2AZLA 4LPGF 4LTVA 2ZCQA 5JA0F 1WMWA 4JYXA 5H9DA 3MAVA 3PYAA 3P5PA 4LIXA 3ACWA 3WJOA 3W7FA 3IBAA 1N20A 3AE0A 2AEKA 2E94A 3EGTA 1YHLA 3WCEA 5DGMF 1N23A 4LTZA 5A0KA 4NUAA 4DHDA 3KROB 3AQBB 2RAHA 5AHUB 3NRIA 3SDTA 4LA6A 2Q9YA 5E8KA 1RQIA 1RQJA 5IMIA 3WJKA 4UMJA 5B0MA 3WCIA 2AZKA 2ZY1A 3N1WF 3KRFB 3LGKA 4RXCA 4L2XF 2E8WA 5IN8A 2E8VA 3N5JF 2ZEUA 3SAEA 3G4DA 4JXYA 2Z4XA 5ILHA 3KROA 2PS7A 1YHMA 2J1PA 1V4HA 3S9VA 2ONGA 3N46F 3P41A 5B02A 1N22A 2Q80A 2PS5A 1JFGA 4P0WA 3SDQA 2E90A 4KVDA 2E91A 4PVYF 5DHIA 5HN7A 5IK6A 3V66A 1VG2A 2E8XA 2F8ZF 2O1OA 2Z50A 4PVXF 4KPJA 2Z7IA 3IPIA 5E8LA 1HXAA 4KVYA 3V1VA 1HM4A 3KRFA 3NF2A 5C05A 2EWGA 4LPHF 2Z7HA 3VJ9A 2Z78A 5AELA 1KIZA 2J1OA 3VJDA 4XQRF 3OYRA 3LDWA 3WCDA 4FJQA 4LZ3A 4MC0A 2E93A 3VJEA 1DI1A 3WCLA 2OPNA 2P1CA 1YYQA 4KVIA 4RXEA 5IMPA 5EASA 3LG5A 5B00A 5ERNA 3LZ9A 5KSXF 4LFVF 3M0GA 5EATA 1DGPA 3ICNA 4E9UA 1UBWA 4H5CF 3ADZA 5DZ2A 4DWGA 3ACYA 3RBMA 3LLWA 4H5EF 4LLTA 3ZL6A 1UBYA 3Q2QA 3ICKA 3WCGA 3WCHA 4JZBA 3N6KF 2Q9ZA 1VG6A 3RYEA 2H8OA 4E9ZA 1YHKA 3APZA 5B03A 4LZ0A 5ILDA 2Z4WA 4P0XA 3CKEA 3P5RA 4H5DF 4KQUA 3TS7A 5ERMA 3KBKA 1KIYA 3ZMBA 5B0KA 1YYSA 4JXNA 4KUXA 4NKEA 1PS1A 4RYPA 5B01A 1FPSA 4DI5A 2VF6A 3Q2ZA 4QPFA 4K10A 4LFGA 5JV1F 2E95A 2ZCSA 4LFEA 2ZCRA 5ILZA 3RMGA 3VJAA 4LUUA 3WSBA 3LK5A 5DIQF 5CG5A 5ILKA 5HN9A 3N0FA 4P0VA 4JZXA 3VJCA 5A0IA 3WCCA 2FORA 4KK2A 1V4JA 3EFQA 4EA1A 4GP2A 3WCMA 1YQ7A 4F6VA 3LGZB 4MC8A 5IK9A 3M02A 3TFNA 2ONHA 5A0JA 4DZWA 2F94F 3OACB 4MC3A 3WEIA 3ZCDA 4DXJA 5IL8A 2E92A 5B0LA 4KVWA 2DH4A 2OGDA 4E1EA 1WKZA 3WCAA 2Q58A 1N1ZA 1ZW5A 3M01A 3WEFA 3NPRA 4NG6A 5DJPF 4LZCA 3Q30A 3DYGA 5IKAA 5DGNF 2PS6A 4OKZA 3SDRA 4F62A 4RNQA 3P8LA 4F6XA 3AQCB 3OACA 3N49F 4OMHA 3KRAB 3AQ0A 3ICZA 4N9UA 3ACXA 3N45F 3PKOA 3N0GA 1UBVA 3N5HF 3TC1A 5HNAA 5I1UA 2Z52A 3ICMA 5B0JA 1V4IA 1VG7A 3S4JA 2Z4ZA 3WEGA 2Z4VA 3Q1OA 4KPDA 3PDEA 3BNXA 5DJVF 4NFKF
chains in the Genus database with same CATH superfamily
4QXSF 5IVGA 3DYHA 3M9UA 3RYWA 3KRCB 3LVSA 4OMGA 5DW7A 5IM1A 2I19A 5ER8A 2F92F 2OPMA 3ASXA 4LOBA 3KRAA 3WEHA 4EA0A 4KQ5A 1YYTA 3WEJA 1VG3A 2PS8A 1WL3A 3WCJA 5EROA 3WSAA 3SDVA 3MZVA 1N1BA 4LLSA 1JFAA 4XQSF 2E8TA 3M00A 5DJRF 3NPKA 3TFPA 5EAUA 4RXAA 4EA2A 4Q23A 1V4KA 1WL2A 5ILJA 3KRCA 4DWBA 4KFAA 4XQTF 2AETA 3G4FA 1RTRA 3KRPB 5DHKA 4OKMA 5IKHA 3N3LF 2AELA 4OGUA 5E8HA 3DYFA 5AYPA 2ZEVA 4N1ZF 4GA3A 2OA6A 5DGSF 3P8RA 5JUZF 4FP4A 4NKFA 5IMNA 3TFVA 3PYBA 3VJ8A 3CC9A 2ZCOA 3UCAA 5JV2F 3BNYA 3QQVA 2Z4YA 4DEMF 3SDUA 3N3DA 5HN8A 1N24A 2QISA 3KRPA 3LEEA 3N1VF 2F7MF 3EZ3A 1WY0A 4JVJF 2FTZA 3LSNA 3WJNA 4KQSA 2E4OA 2F9KF 3QKCA 2E8UA 3ID0A 3WE9A 3WEKA 1YJ4A 3LJIA 3VJBA 3WC9A 4GP1A 5B0IA 2AZJA 2J5CA 4KWDA 3ZMCA 1HXGA 3KB9A 3CP6A 1HM7A 3OABB 4HD1A 4KKMA 1WL1A 4NFJF 3LOMA 5JV0F 1YYUA 3ZOUA 5IK0A 5CG6A 1V4EA 1EZFA 5ILYA 4WK5A 1YV5A 1HXCA 3V1XA 4LA5A 3WCFA 2PS4A 4ZQ8A 1HX9A 4GAXA 1UBXA 2F8CF 2F89F 3WCBA 4RXDA 3LMDA 5ILIA 3B7LA 1VG4A 4LXWA 3OABA 4NFIF 1N21A 1YYRA 1WL0A 3PH7A 5IL3A 5AFXA 2AZLA 4LPGF 4LTVA 2ZCQA 5JA0F 1WMWA 4JYXA 5H9DA 3MAVA 3PYAA 3P5PA 4LIXA 3ACWA 3WJOA 3W7FA 3IBAA 1N20A 3AE0A 2AEKA 2E94A 3EGTA 1YHLA 3WCEA 5DGMF 1N23A 4LTZA 5A0KA 4NUAA 4DHDA 3KROB 3AQBB 2RAHA 5AHUB 3NRIA 3SDTA 4LA6A 2Q9YA 5E8KA 1RQIA 1RQJA 5IMIA 3WJKA 4UMJA 5B0MA 3WCIA 2AZKA 2ZY1A 3N1WF 3KRFB 3LGKA 4RXCA 4L2XF 2E8WA 5IN8A 2E8VA 3N5JF 2ZEUA 3SAEA 3G4DA 4JXYA 2Z4XA 5ILHA 3KROA 2PS7A 1YHMA 2J1PA 1V4HA 3S9VA 2ONGA 3N46F 3P41A 5B02A 1N22A 2Q80A 2PS5A 1JFGA 4P0WA 3SDQA 2E90A 4KVDA 2E91A 4PVYF 5DHIA 5HN7A 5IK6A 3V66A 1VG2A 2E8XA 2F8ZF 2O1OA 2Z50A 4PVXF 4KPJA 2Z7IA 3IPIA 5E8LA 1HXAA 4KVYA 3V1VA 1HM4A 3KRFA 3NF2A 5C05A 2EWGA 4LPHF 2Z7HA 3VJ9A 2Z78A 5AELA 1KIZA 2J1OA 3VJDA 4XQRF 3OYRA 3LDWA 3WCDA 4FJQA 4LZ3A 4MC0A 2E93A 3VJEA 1DI1A 3WCLA 2OPNA 2P1CA 1YYQA 4KVIA 4RXEA 5IMPA 5EASA 3LG5A 5B00A 5ERNA 3LZ9A 5KSXF 4LFVF 3M0GA 5EATA 1DGPA 3ICNA 4E9UA 1UBWA 4H5CF 3ADZA 5DZ2A 4DWGA 3ACYA 3RBMA 3LLWA 4H5EF 4LLTA 3ZL6A 1UBYA 3Q2QA 3ICKA 3WCGA 3WCHA 4JZBA 3N6KF 2Q9ZA 1VG6A 3RYEA 2H8OA 4E9ZA 1YHKA 3APZA 5B03A 4LZ0A 5ILDA 2Z4WA 4P0XA 3CKEA 3P5RA 4H5DF 4KQUA 3TS7A 5ERMA 3KBKA 1KIYA 3ZMBA 5B0KA 1YYSA 4JXNA 4KUXA 4NKEA 1PS1A 4RYPA 5B01A 1FPSA 4DI5A 2VF6A 3Q2ZA 4QPFA 4K10A 4LFGA 5JV1F 2E95A 2ZCSA 4LFEA 2ZCRA 5ILZA 3RMGA 3VJAA 4LUUA 3WSBA 3LK5A 5DIQF 5CG5A 5ILKA 5HN9A 3N0FA 4P0VA 4JZXA 3VJCA 5A0IA 3WCCA 2FORA 4KK2A 1V4JA 3EFQA 4EA1A 4GP2A 3WCMA 1YQ7A 4F6VA 3LGZB 4MC8A 5IK9A 3M02A 3TFNA 2ONHA 5A0JA 4DZWA 2F94F 3OACB 4MC3A 3WEIA 3ZCDA 4DXJA 5IL8A 2E92A 5B0LA 4KVWA 2DH4A 2OGDA 4E1EA 1WKZA 3WCAA 2Q58A 1N1ZA 1ZW5A 3M01A 3WEFA 3NPRA 4NG6A 5DJPF 4LZCA 3Q30A 3DYGA 5IKAA 5DGNF 2PS6A 4OKZA 3SDRA 4F62A 4RNQA 3P8LA 4F6XA 3AQCB 3OACA 3N49F 4OMHA 3KRAB 3AQ0A 3ICZA 4N9UA 3ACXA 3N45F 3PKOA 3N0GA 1UBVA 3N5HF 3TC1A 5HNAA 5I1UA 2Z52A 3ICMA 5B0JA 1V4IA 1VG7A 3S4JA 2Z4ZA 3WEGA 2Z4VA 3Q1OA 4KPDA 3PDEA 3BNXA 5DJVF 4NFKF
chains in the Genus database with same CATH topology
4QXSF 5IVGA 3DYHA 3M9UA 3RYWA 3KRCB 3LVSA 4OMGA 5DW7A 5IM1A 2I19A 5ER8A 2F92F 2OPMA 3ASXA 4LOBA 3KRAA 3WEHA 4EA0A 4KQ5A 1YYTA 3WEJA 1VG3A 2PS8A 1WL3A 3WCJA 5EROA 3WSAA 3SDVA 3MZVA 1N1BA 4LLSA 1JFAA 4XQSF 2E8TA 3M00A 5DJRF 3NPKA 3TFPA 5EAUA 4RXAA 4EA2A 4Q23A 1V4KA 1WL2A 5ILJA 3KRCA 4DWBA 4KFAA 4XQTF 2AETA 3G4FA 1RTRA 3KRPB 5DHKA 4OKMA 5IKHA 3N3LF 2AELA 4OGUA 5E8HA 3DYFA 5AYPA 2ZEVA 4N1ZF 4GA3A 2OA6A 5DGSF 3P8RA 5JUZF 4FP4A 4NKFA 5IMNA 3TFVA 3PYBA 3VJ8A 3CC9A 2ZCOA 3UCAA 5JV2F 3BNYA 3QQVA 2Z4YA 4DEMF 3SDUA 3N3DA 5HN8A 1N24A 2QISA 3KRPA 3LEEA 3N1VF 2F7MF 3EZ3A 1WY0A 4JVJF 2FTZA 3LSNA 3WJNA 4KQSA 2E4OA 2F9KF 3QKCA 2E8UA 3ID0A 3WE9A 3WEKA 1YJ4A 3LJIA 3VJBA 3WC9A 4GP1A 5B0IA 2AZJA 2J5CA 4KWDA 3ZMCA 1HXGA 3KB9A 3CP6A 1HM7A 3OABB 4HD1A 4KKMA 1WL1A 4NFJF 3LOMA 5JV0F 1YYUA 3ZOUA 5IK0A 5CG6A 1V4EA 1EZFA 5ILYA 4WK5A 1YV5A 1HXCA 3V1XA 4LA5A 3WCFA 2PS4A 4ZQ8A 1HX9A 4GAXA 1UBXA 2F8CF 2F89F 3WCBA 4RXDA 3LMDA 5ILIA 3B7LA 1VG4A 4LXWA 3OABA 4NFIF 1N21A 1YYRA 1WL0A 3PH7A 5IL3A 5AFXA 2AZLA 4LPGF 4LTVA 2ZCQA 5JA0F 1WMWA 4JYXA 5H9DA 3MAVA 3PYAA 3P5PA 4LIXA 3ACWA 3WJOA 3W7FA 3IBAA 1N20A 3AE0A 2AEKA 2E94A 3EGTA 1YHLA 3WCEA 5DGMF 1N23A 4LTZA 5A0KA 4NUAA 4DHDA 3KROB 3AQBB 2RAHA 5AHUB 3NRIA 3SDTA 4LA6A 2Q9YA 5E8KA 1RQIA 1RQJA 5IMIA 3WJKA 4UMJA 5B0MA 3WCIA 2AZKA 2ZY1A 3N1WF 3KRFB 3LGKA 4RXCA 4L2XF 2E8WA 5IN8A 2E8VA 3N5JF 2ZEUA 3SAEA 3G4DA 4JXYA 2Z4XA 5ILHA 3KROA 2PS7A 1YHMA 2J1PA 1V4HA 3S9VA 2ONGA 3N46F 3P41A 5B02A 1N22A 2Q80A 2PS5A 1JFGA 4P0WA 3SDQA 2E90A 4KVDA 2E91A 4PVYF 5DHIA 5HN7A 5IK6A 3V66A 1VG2A 2E8XA 2F8ZF 2O1OA 2Z50A 4PVXF 4KPJA 2Z7IA 3IPIA 5E8LA 1HXAA 4KVYA 3V1VA 1HM4A 3KRFA 3NF2A 5C05A 2EWGA 4LPHF 2Z7HA 3VJ9A 2Z78A 5AELA 1KIZA 2J1OA 3VJDA 4XQRF 3OYRA 3LDWA 3WCDA 4FJQA 4LZ3A 4MC0A 2E93A 3VJEA 1DI1A 3WCLA 2OPNA 2P1CA 1YYQA 4KVIA 4RXEA 5IMPA 5EASA 3LG5A 5B00A 5ERNA 3LZ9A 5KSXF 4LFVF 3M0GA 5EATA 1DGPA 3ICNA 4E9UA 1UBWA 4H5CF 3ADZA 5DZ2A 4DWGA 3ACYA 3RBMA 3LLWA 4H5EF 4LLTA 3ZL6A 1UBYA 3Q2QA 3ICKA 3WCGA 3WCHA 4JZBA 3N6KF 2Q9ZA 1VG6A 3RYEA 2H8OA 4E9ZA 1YHKA 3APZA 5B03A 4LZ0A 5ILDA 2Z4WA 4P0XA 3CKEA 3P5RA 4H5DF 4KQUA 3TS7A 5ERMA 3KBKA 1KIYA 3ZMBA 5B0KA 1YYSA 4JXNA 4KUXA 4NKEA 1PS1A 4RYPA 5B01A 1FPSA 4DI5A 2VF6A 3Q2ZA 4QPFA 4K10A 4LFGA 5JV1F 2E95A 2ZCSA 4LFEA 2ZCRA 5ILZA 3RMGA 3VJAA 4LUUA 3WSBA 3LK5A 5DIQF 5CG5A 5ILKA 5HN9A 3N0FA 4P0VA 4JZXA 3VJCA 5A0IA 3WCCA 2FORA 4KK2A 1V4JA 3EFQA 4EA1A 4GP2A 3WCMA 1YQ7A 4F6VA 3LGZB 4MC8A 5IK9A 3M02A 3TFNA 2ONHA 5A0JA 4DZWA 2F94F 3OACB 4MC3A 3WEIA 3ZCDA 4DXJA 5IL8A 2E92A 5B0LA 4KVWA 2DH4A 2OGDA 4E1EA 1WKZA 3WCAA 2Q58A 1N1ZA 1ZW5A 3M01A 3WEFA 3NPRA 4NG6A 5DJPF 4LZCA 3Q30A 3DYGA 5IKAA 5DGNF 2PS6A 4OKZA 3SDRA 4F62A 4RNQA 3P8LA 4F6XA 3AQCB 3OACA 3N49F 4OMHA 3KRAB 3AQ0A 3ICZA 4N9UA 3ACXA 3N45F 3PKOA 3N0GA 1UBVA 3N5HF 3TC1A 5HNAA 5I1UA 2Z52A 3ICMA 5B0JA 1V4IA 1VG7A 3S4JA 2Z4ZA 3WEGA 2Z4VA 3Q1OA 4KPDA 3PDEA 3BNXA 5DJVF 4NFKF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QXS F;  5IVG A;  3DYH A;  3M9U A;  3RYW A;  3KRC B;  3LVS A;  4OMG A;  5DW7 A;  5IM1 A;  2I19 A;  5ER8 A;  2F92 F;  2OPM A;  3ASX A;  4LOB A;  3KRA A;  3WEH A;  4EA0 A;  4KQ5 A;  1YYT A;  3WEJ A;  1VG3 A;  2PS8 A;  1WL3 A;  3WCJ A;  5ERO A;  3WSA A;  3SDV A;  3MZV A;  1N1B A;  4LLS A;  1JFA A;  4XQS F;  2E8T A;  3M00 A;  5DJR F;  3NPK A;  3TFP A;  5EAU A;  4RXA A;  4EA2 A;  4Q23 A;  1V4K A;  1WL2 A;  5ILJ A;  3KRC A;  4DWB A;  4KFA A;  4XQT F;  2AET A;  3G4F A;  1RTR A;  3KRP B;  5DHK A;  4OKM A;  5IKH A;  3N3L F;  2AEL A;  4OGU A;  5E8H A;  3DYF A;  5AYP A;  2ZEV A;  4N1Z F;  4GA3 A;  2OA6 A;  5DGS F;  3P8R A;  5JUZ F;  4FP4 A;  4NKF A;  5IMN A;  3TFV A;  3PYB A;  3VJ8 A;  3CC9 A;  2ZCO A;  3UCA A;  5JV2 F;  3BNY A;  3QQV A;  2Z4Y A;  4DEM F;  3SDU A;  3N3D A;  5HN8 A;  1N24 A;  2QIS A;  3KRP A;  3LEE A;  3N1V F;  2F7M F;  3EZ3 A;  1WY0 A;  4JVJ F;  2FTZ A;  3LSN A;  3WJN A;  4KQS A;  2E4O A;  2F9K F;  3QKC A;  2E8U A;  3ID0 A;  3WE9 A;  3WEK A;  1YJ4 A;  3LJI A;  3VJB A;  3WC9 A;  4GP1 A;  5B0I A;  2AZJ A;  2J5C A;  4KWD A;  3ZMC A;  1HXG A;  3KB9 A;  3CP6 A;  1HM7 A;  3OAB B;  4HD1 A;  4KKM A;  1WL1 A;  4NFJ F;  3LOM A;  5JV0 F;  1YYU A;  3ZOU A;  5IK0 A;  5CG6 A;  1V4E A;  1EZF A;  5ILY A;  4WK5 A;  1YV5 A;  1HXC A;  3V1X A;  4LA5 A;  3WCF A;  2PS4 A;  4ZQ8 A;  1HX9 A;  4GAX A;  1UBX A;  2F8C F;  2F89 F;  3WCB A;  4RXD A;  3LMD A;  5ILI A;  3B7L A;  1VG4 A;  4LXW A;  3OAB A;  4NFI F;  1N21 A;  1YYR A;  1WL0 A;  3PH7 A;  5IL3 A;  5AFX A;  2AZL A;  4LPG F;  4LTV A;  2ZCQ A;  5JA0 F;  1WMW A;  4JYX A;  5H9D A;  3MAV A;  3PYA A;  3P5P A;  4LIX A;  3ACW A;  3WJO A;  3W7F A;  3IBA A;  1N20 A;  3AE0 A;  2AEK A;  2E94 A;  3EGT A;  1YHL A;  3WCE A;  5DGM F;  1N23 A;  4LTZ A;  5A0K A;  4NUA A;  4DHD A;  3KRO B;  3AQB B;  2RAH A;  5AHU B;  3NRI A;  3SDT A;  4LA6 A;  2Q9Y A;  5E8K A;  1RQI A;  1RQJ A;  5IMI A;  3WJK A;  4UMJ A;  5B0M A;  3WCI A;  2AZK A;  2ZY1 A;  3N1W F;  3KRF B;  3LGK A;  4RXC A;  4L2X F;  2E8W A;  5IN8 A;  2E8V A;  3N5J F;  2ZEU A;  3SAE A;  3G4D A;  4JXY A;  2Z4X A;  5ILH A;  3KRO A;  2PS7 A;  1YHM A;  2J1P A;  1V4H A;  3S9V A;  2ONG A;  3N46 F;  3P41 A;  5B02 A;  1N22 A;  2Q80 A;  2PS5 A;  1JFG A;  4P0W A;  3SDQ A;  2E90 A;  4KVD A;  2E91 A;  4PVY F;  5DHI A;  5HN7 A;  5IK6 A;  3V66 A;  1VG2 A;  2E8X A;  2F8Z F;  2O1O A;  2Z50 A;  4PVX F;  4KPJ A;  2Z7I A;  3IPI A;  5E8L A;  1HXA A;  4KVY A;  3V1V A;  1HM4 A;  3KRF A;  3NF2 A;  5C05 A;  2EWG A;  4LPH F;  2Z7H A;  3VJ9 A;  2Z78 A;  5AEL A;  1KIZ A;  2J1O A;  3VJD A;  4XQR F;  3OYR A;  3LDW A;  3WCD A;  4FJQ A;  4LZ3 A;  4MC0 A;  2E93 A;  3VJE A;  1DI1 A;  3WCL A;  2OPN A;  2P1C A;  1YYQ A;  4KVI A;  4RXE A;  5IMP A;  5EAS A;  3LG5 A;  5B00 A;  5ERN A;  3LZ9 A;  5KSX F;  4LFV F;  3M0G A;  5EAT A;  1DGP A;  3ICN A;  4E9U A;  1UBW A;  4H5C F;  3ADZ A;  5DZ2 A;  4DWG A;  3ACY A;  3RBM A;  3LLW A;  4H5E F;  4LLT A;  3ZL6 A;  1UBY A;  3Q2Q A;  3ICK A;  3WCG A;  3WCH A;  4JZB A;  3N6K F;  2Q9Z A;  1VG6 A;  3RYE A;  2H8O A;  4E9Z A;  1YHK A;  3APZ A;  5B03 A;  4LZ0 A;  5ILD A;  2Z4W A;  4P0X A;  3CKE A;  3P5R A;  4H5D F;  4KQU A;  3TS7 A;  5ERM A;  3KBK A;  1KIY A;  3ZMB A;  5B0K A;  1YYS A;  4JXN A;  4KUX A;  4NKE A;  1PS1 A;  4RYP A;  5B01 A;  1FPS A;  4DI5 A;  2VF6 A;  3Q2Z A;  4QPF A;  4K10 A;  4LFG A;  5JV1 F;  2E95 A;  2ZCS A;  4LFE A;  2ZCR A;  5ILZ A;  3RMG A;  3VJA A;  4LUU A;  3WSB A;  3LK5 A;  5DIQ F;  5CG5 A;  5ILK A;  5HN9 A;  3N0F A;  4P0V A;  4JZX A;  3VJC A;  5A0I A;  3WCC A;  2FOR A;  4KK2 A;  1V4J A;  3EFQ A;  4EA1 A;  4GP2 A;  3WCM A;  1YQ7 A;  4F6V A;  3LGZ B;  4MC8 A;  5IK9 A;  3M02 A;  3TFN A;  2ONH A;  5A0J A;  4DZW A;  2F94 F;  3OAC B;  4MC3 A;  3WEI A;  3ZCD A;  4DXJ A;  5IL8 A;  2E92 A;  5B0L A;  4KVW A;  2DH4 A;  2OGD A;  4E1E A;  1WKZ A;  3WCA A;  2Q58 A;  1N1Z A;  1ZW5 A;  3M01 A;  3WEF A;  3NPR A;  4NG6 A;  5DJP F;  4LZC A;  3Q30 A;  3DYG A;  5IKA A;  5DGN F;  2PS6 A;  4OKZ A;  3SDR A;  4F62 A;  4RNQ A;  3P8L A;  4F6X A;  3AQC B;  3OAC A;  3N49 F;  4OMH A;  3KRA B;  3AQ0 A;  3ICZ A;  4N9U A;  3ACX A;  3N45 F;  3PKO A;  3N0G A;  1UBV A;  3N5H F;  3TC1 A;  5HNA A;  5I1U A;  2Z52 A;  3ICM A;  5B0J A;  1V4I A;  1VG7 A;  3S4J A;  2Z4Z A;  3WEG A;  2Z4V A;  3Q1O A;  4KPD A;  3PDE A;  3BNX A;  5DJV F;  4NFK F; 
#chains in the Genus database with same CATH topology
 4QXS F;  5IVG A;  3DYH A;  3M9U A;  3RYW A;  3KRC B;  3LVS A;  4OMG A;  5DW7 A;  5IM1 A;  2I19 A;  5ER8 A;  2F92 F;  2OPM A;  3ASX A;  4LOB A;  3KRA A;  3WEH A;  4EA0 A;  4KQ5 A;  1YYT A;  3WEJ A;  1VG3 A;  2PS8 A;  1WL3 A;  3WCJ A;  5ERO A;  3WSA A;  3SDV A;  3MZV A;  1N1B A;  4LLS A;  1JFA A;  4XQS F;  2E8T A;  3M00 A;  5DJR F;  3NPK A;  3TFP A;  5EAU A;  4RXA A;  4EA2 A;  4Q23 A;  1V4K A;  1WL2 A;  5ILJ A;  3KRC A;  4DWB A;  4KFA A;  4XQT F;  2AET A;  3G4F A;  1RTR A;  3KRP B;  5DHK A;  4OKM A;  5IKH A;  3N3L F;  2AEL A;  4OGU A;  5E8H A;  3DYF A;  5AYP A;  2ZEV A;  4N1Z F;  4GA3 A;  2OA6 A;  5DGS F;  3P8R A;  5JUZ F;  4FP4 A;  4NKF A;  5IMN A;  3TFV A;  3PYB A;  3VJ8 A;  3CC9 A;  2ZCO A;  3UCA A;  5JV2 F;  3BNY A;  3QQV A;  2Z4Y A;  4DEM F;  3SDU A;  3N3D A;  5HN8 A;  1N24 A;  2QIS A;  3KRP A;  3LEE A;  3N1V F;  2F7M F;  3EZ3 A;  1WY0 A;  4JVJ F;  2FTZ A;  3LSN A;  3WJN A;  4KQS A;  2E4O A;  2F9K F;  3QKC A;  2E8U A;  3ID0 A;  3WE9 A;  3WEK A;  1YJ4 A;  3LJI A;  3VJB A;  3WC9 A;  4GP1 A;  5B0I A;  2AZJ A;  2J5C A;  4KWD A;  3ZMC A;  1HXG A;  3KB9 A;  3CP6 A;  1HM7 A;  3OAB B;  4HD1 A;  4KKM A;  1WL1 A;  4NFJ F;  3LOM A;  5JV0 F;  1YYU A;  3ZOU A;  5IK0 A;  5CG6 A;  1V4E A;  1EZF A;  5ILY A;  4WK5 A;  1YV5 A;  1HXC A;  3V1X A;  4LA5 A;  3WCF A;  2PS4 A;  4ZQ8 A;  1HX9 A;  4GAX A;  1UBX A;  2F8C F;  2F89 F;  3WCB A;  4RXD A;  3LMD A;  5ILI A;  3B7L A;  1VG4 A;  4LXW A;  3OAB A;  4NFI F;  1N21 A;  1YYR A;  1WL0 A;  3PH7 A;  5IL3 A;  5AFX A;  2AZL A;  4LPG F;  4LTV A;  2ZCQ A;  5JA0 F;  1WMW A;  4JYX A;  5H9D A;  3MAV A;  3PYA A;  3P5P A;  4LIX A;  3ACW A;  3WJO A;  3W7F A;  3IBA A;  1N20 A;  3AE0 A;  2AEK A;  2E94 A;  3EGT A;  1YHL A;  3WCE A;  5DGM F;  1N23 A;  4LTZ A;  5A0K A;  4NUA A;  4DHD A;  3KRO B;  3AQB B;  2RAH A;  5AHU B;  3NRI A;  3SDT A;  4LA6 A;  2Q9Y A;  5E8K A;  1RQI A;  1RQJ A;  5IMI A;  3WJK A;  4UMJ A;  5B0M A;  3WCI A;  2AZK A;  2ZY1 A;  3N1W F;  3KRF B;  3LGK A;  4RXC A;  4L2X F;  2E8W A;  5IN8 A;  2E8V A;  3N5J F;  2ZEU A;  3SAE A;  3G4D A;  4JXY A;  2Z4X A;  5ILH A;  3KRO A;  2PS7 A;  1YHM A;  2J1P A;  1V4H A;  3S9V A;  2ONG A;  3N46 F;  3P41 A;  5B02 A;  1N22 A;  2Q80 A;  2PS5 A;  1JFG A;  4P0W A;  3SDQ A;  2E90 A;  4KVD A;  2E91 A;  4PVY F;  5DHI A;  5HN7 A;  5IK6 A;  3V66 A;  1VG2 A;  2E8X A;  2F8Z F;  2O1O A;  2Z50 A;  4PVX F;  4KPJ A;  2Z7I A;  3IPI A;  5E8L A;  1HXA A;  4KVY A;  3V1V A;  1HM4 A;  3KRF A;  3NF2 A;  5C05 A;  2EWG A;  4LPH F;  2Z7H A;  3VJ9 A;  2Z78 A;  5AEL A;  1KIZ A;  2J1O A;  3VJD A;  4XQR F;  3OYR A;  3LDW A;  3WCD A;  4FJQ A;  4LZ3 A;  4MC0 A;  2E93 A;  3VJE A;  1DI1 A;  3WCL A;  2OPN A;  2P1C A;  1YYQ A;  4KVI A;  4RXE A;  5IMP A;  5EAS A;  3LG5 A;  5B00 A;  5ERN A;  3LZ9 A;  5KSX F;  4LFV F;  3M0G A;  5EAT A;  1DGP A;  3ICN A;  4E9U A;  1UBW A;  4H5C F;  3ADZ A;  5DZ2 A;  4DWG A;  3ACY A;  3RBM A;  3LLW A;  4H5E F;  4LLT A;  3ZL6 A;  1UBY A;  3Q2Q A;  3ICK A;  3WCG A;  3WCH A;  4JZB A;  3N6K F;  2Q9Z A;  1VG6 A;  3RYE A;  2H8O A;  4E9Z A;  1YHK A;  3APZ A;  5B03 A;  4LZ0 A;  5ILD A;  2Z4W A;  4P0X A;  3CKE A;  3P5R A;  4H5D F;  4KQU A;  3TS7 A;  5ERM A;  3KBK A;  1KIY A;  3ZMB A;  5B0K A;  1YYS A;  4JXN A;  4KUX A;  4NKE A;  1PS1 A;  4RYP A;  5B01 A;  1FPS A;  4DI5 A;  2VF6 A;  3Q2Z A;  4QPF A;  4K10 A;  4LFG A;  5JV1 F;  2E95 A;  2ZCS A;  4LFE A;  2ZCR A;  5ILZ A;  3RMG A;  3VJA A;  4LUU A;  3WSB A;  3LK5 A;  5DIQ F;  5CG5 A;  5ILK A;  5HN9 A;  3N0F A;  4P0V A;  4JZX A;  3VJC A;  5A0I A;  3WCC A;  2FOR A;  4KK2 A;  1V4J A;  3EFQ A;  4EA1 A;  4GP2 A;  3WCM A;  1YQ7 A;  4F6V A;  3LGZ B;  4MC8 A;  5IK9 A;  3M02 A;  3TFN A;  2ONH A;  5A0J A;  4DZW A;  2F94 F;  3OAC B;  4MC3 A;  3WEI A;  3ZCD A;  4DXJ A;  5IL8 A;  2E92 A;  5B0L A;  4KVW A;  2DH4 A;  2OGD A;  4E1E A;  1WKZ A;  3WCA A;  2Q58 A;  1N1Z A;  1ZW5 A;  3M01 A;  3WEF A;  3NPR A;  4NG6 A;  5DJP F;  4LZC A;  3Q30 A;  3DYG A;  5IKA A;  5DGN F;  2PS6 A;  4OKZ A;  3SDR A;  4F62 A;  4RNQ A;  3P8L A;  4F6X A;  3AQC B;  3OAC A;  3N49 F;  4OMH A;  3KRA B;  3AQ0 A;  3ICZ A;  4N9U A;  3ACX A;  3N45 F;  3PKO A;  3N0G A;  1UBV A;  3N5H F;  3TC1 A;  5HNA A;  5I1U A;  2Z52 A;  3ICM A;  5B0J A;  1V4I A;  1VG7 A;  3S4J A;  2Z4Z A;  3WEG A;  2Z4V A;  3Q1O A;  4KPD A;  3PDE A;  3BNX A;  5DJV F;  4NFK F; 
#chains in the Genus database with same CATH homology
 4QXS F;  5IVG A;  3DYH A;  3M9U A;  3RYW A;  3KRC B;  3LVS A;  4OMG A;  5DW7 A;  5IM1 A;  2I19 A;  5ER8 A;  2F92 F;  2OPM A;  3ASX A;  4LOB A;  3KRA A;  3WEH A;  4EA0 A;  4KQ5 A;  1YYT A;  3WEJ A;  1VG3 A;  2PS8 A;  1WL3 A;  3WCJ A;  5ERO A;  3WSA A;  3SDV A;  3MZV A;  1N1B A;  4LLS A;  1JFA A;  4XQS F;  2E8T A;  3M00 A;  5DJR F;  3NPK A;  3TFP A;  5EAU A;  4RXA A;  4EA2 A;  4Q23 A;  1V4K A;  1WL2 A;  5ILJ A;  3KRC A;  4DWB A;  4KFA A;  4XQT F;  2AET A;  3G4F A;  1RTR A;  3KRP B;  5DHK A;  4OKM A;  5IKH A;  3N3L F;  2AEL A;  4OGU A;  5E8H A;  3DYF A;  5AYP A;  2ZEV A;  4N1Z F;  4GA3 A;  2OA6 A;  5DGS F;  3P8R A;  5JUZ F;  4FP4 A;  4NKF A;  5IMN A;  3TFV A;  3PYB A;  3VJ8 A;  3CC9 A;  2ZCO A;  3UCA A;  5JV2 F;  3BNY A;  3QQV A;  2Z4Y A;  4DEM F;  3SDU A;  3N3D A;  5HN8 A;  1N24 A;  2QIS A;  3KRP A;  3LEE A;  3N1V F;  2F7M F;  3EZ3 A;  1WY0 A;  4JVJ F;  2FTZ A;  3LSN A;  3WJN A;  4KQS A;  2E4O A;  2F9K F;  3QKC A;  2E8U A;  3ID0 A;  3WE9 A;  3WEK A;  1YJ4 A;  3LJI A;  3VJB A;  3WC9 A;  4GP1 A;  5B0I A;  2AZJ A;  2J5C A;  4KWD A;  3ZMC A;  1HXG A;  3KB9 A;  3CP6 A;  1HM7 A;  3OAB B;  4HD1 A;  4KKM A;  1WL1 A;  4NFJ F;  3LOM A;  5JV0 F;  1YYU A;  3ZOU A;  5IK0 A;  5CG6 A;  1V4E A;  1EZF A;  5ILY A;  4WK5 A;  1YV5 A;  1HXC A;  3V1X A;  4LA5 A;  3WCF A;  2PS4 A;  4ZQ8 A;  1HX9 A;  4GAX A;  1UBX A;  2F8C F;  2F89 F;  3WCB A;  4RXD A;  3LMD A;  5ILI A;  3B7L A;  1VG4 A;  4LXW A;  3OAB A;  4NFI F;  1N21 A;  1YYR A;  1WL0 A;  3PH7 A;  5IL3 A;  5AFX A;  2AZL A;  4LPG F;  4LTV A;  2ZCQ A;  5JA0 F;  1WMW A;  4JYX A;  5H9D A;  3MAV A;  3PYA A;  3P5P A;  4LIX A;  3ACW A;  3WJO A;  3W7F A;  3IBA A;  1N20 A;  3AE0 A;  2AEK A;  2E94 A;  3EGT A;  1YHL A;  3WCE A;  5DGM F;  1N23 A;  4LTZ A;  5A0K A;  4NUA A;  4DHD A;  3KRO B;  3AQB B;  2RAH A;  5AHU B;  3NRI A;  3SDT A;  4LA6 A;  2Q9Y A;  5E8K A;  1RQI A;  1RQJ A;  5IMI A;  3WJK A;  4UMJ A;  5B0M A;  3WCI A;  2AZK A;  2ZY1 A;  3N1W F;  3KRF B;  3LGK A;  4RXC A;  4L2X F;  2E8W A;  5IN8 A;  2E8V A;  3N5J F;  2ZEU A;  3SAE A;  3G4D A;  4JXY A;  2Z4X A;  5ILH A;  3KRO A;  2PS7 A;  1YHM A;  2J1P A;  1V4H A;  3S9V A;  2ONG A;  3N46 F;  3P41 A;  5B02 A;  1N22 A;  2Q80 A;  2PS5 A;  1JFG A;  4P0W A;  3SDQ A;  2E90 A;  4KVD A;  2E91 A;  4PVY F;  5DHI A;  5HN7 A;  5IK6 A;  3V66 A;  1VG2 A;  2E8X A;  2F8Z F;  2O1O A;  2Z50 A;  4PVX F;  4KPJ A;  2Z7I A;  3IPI A;  5E8L A;  1HXA A;  4KVY A;  3V1V A;  1HM4 A;  3KRF A;  3NF2 A;  5C05 A;  2EWG A;  4LPH F;  2Z7H A;  3VJ9 A;  2Z78 A;  5AEL A;  1KIZ A;  2J1O A;  3VJD A;  4XQR F;  3OYR A;  3LDW A;  3WCD A;  4FJQ A;  4LZ3 A;  4MC0 A;  2E93 A;  3VJE A;  1DI1 A;  3WCL A;  2OPN A;  2P1C A;  1YYQ A;  4KVI A;  4RXE A;  5IMP A;  5EAS A;  3LG5 A;  5B00 A;  5ERN A;  3LZ9 A;  5KSX F;  4LFV F;  3M0G A;  5EAT A;  1DGP A;  3ICN A;  4E9U A;  1UBW A;  4H5C F;  3ADZ A;  5DZ2 A;  4DWG A;  3ACY A;  3RBM A;  3LLW A;  4H5E F;  4LLT A;  3ZL6 A;  1UBY A;  3Q2Q A;  3ICK A;  3WCG A;  3WCH A;  4JZB A;  3N6K F;  2Q9Z A;  1VG6 A;  3RYE A;  2H8O A;  4E9Z A;  1YHK A;  3APZ A;  5B03 A;  4LZ0 A;  5ILD A;  2Z4W A;  4P0X A;  3CKE A;  3P5R A;  4H5D F;  4KQU A;  3TS7 A;  5ERM A;  3KBK A;  1KIY A;  3ZMB A;  5B0K A;  1YYS A;  4JXN A;  4KUX A;  4NKE A;  1PS1 A;  4RYP A;  5B01 A;  1FPS A;  4DI5 A;  2VF6 A;  3Q2Z A;  4QPF A;  4K10 A;  4LFG A;  5JV1 F;  2E95 A;  2ZCS A;  4LFE A;  2ZCR A;  5ILZ A;  3RMG A;  3VJA A;  4LUU A;  3WSB A;  3LK5 A;  5DIQ F;  5CG5 A;  5ILK A;  5HN9 A;  3N0F A;  4P0V A;  4JZX A;  3VJC A;  5A0I A;  3WCC A;  2FOR A;  4KK2 A;  1V4J A;  3EFQ A;  4EA1 A;  4GP2 A;  3WCM A;  1YQ7 A;  4F6V A;  3LGZ B;  4MC8 A;  5IK9 A;  3M02 A;  3TFN A;  2ONH A;  5A0J A;  4DZW A;  2F94 F;  3OAC B;  4MC3 A;  3WEI A;  3ZCD A;  4DXJ A;  5IL8 A;  2E92 A;  5B0L A;  4KVW A;  2DH4 A;  2OGD A;  4E1E A;  1WKZ A;  3WCA A;  2Q58 A;  1N1Z A;  1ZW5 A;  3M01 A;  3WEF A;  3NPR A;  4NG6 A;  5DJP F;  4LZC A;  3Q30 A;  3DYG A;  5IKA A;  5DGN F;  2PS6 A;  4OKZ A;  3SDR A;  4F62 A;  4RNQ A;  3P8L A;  4F6X A;  3AQC B;  3OAC A;  3N49 F;  4OMH A;  3KRA B;  3AQ0 A;  3ICZ A;  4N9U A;  3ACX A;  3N45 F;  3PKO A;  3N0G A;  1UBV A;  3N5H F;  3TC1 A;  5HNA A;  5I1U A;  2Z52 A;  3ICM A;  5B0J A;  1V4I A;  1VG7 A;  3S4J A;  2Z4Z A;  3WEG A;  2Z4V A;  3Q1O A;  4KPD A;  3PDE A;  3BNX A;  5DJV F;  4NFK F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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