3VJCA

Crystal structure of the human squalene synthase in complex with zaragozic acid a
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
334
structure length
334
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Squalene synthase
publication title Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/transferase inhibitor
total genus 133
structure length 334
sequence length 334
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2011-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3vjcA00
1YQ7A 5CG5A 3WCDA 4KUXA 3KROB 2AZJA 5ILIA 2E8TA 4GP2A 3PKOA 4PVYF 3WE9A 3LVSA 3VJ9A 4DEMF 1EZFA 4FP4A 4MC8A 5IVGA 3NF2A 2QISA 3WEHA 2E91A 3RBMA 2ZY1A 3LMDA 3Q2ZA 1N22A 3KRPA 5B00A 3Q2QA 2Z7IA 3BNYA 2ZCRA 1JFAA 1RQJA 2PS4A 5HN8A 3SDRA 4F6XA 3M0GA 3WCJA 3WJKA 5IK9A 3RYWA 3VJ8A 5DIQF 4LFEA 3V1XA 3KRCB 5IL8A 4KFAA 1YJ4A 2ZCSA 2Z78A 3LSNA 2PS8A 3DYFA 3KB9A 4KVWA 3P5RA 3KRPB 3KBKA 4JYXA 1VG7A 4XQRF 3OABA 5DW7A 3LJIA 5IK6A 4PVXF 3NPKA 3LLWA 1YYTA 3PH7A 3LOMA 3BNXA 3ACYA 4LFVF 2F92F 3ASXA 3VJDA 5DZ2A 4OMHA 5DGSF 4N9UA 1HM7A 4LTVA 5ILYA 3N3DA 3B7LA 1JFGA 3P41A 1V4KA 2PS5A 3KROA 4LA6A 4RXEA 1DGPA 3WCBA 3SDTA 2VF6A 4P0XA 3M00A 3M9UA 1UBVA 4LPGF 3N0FA 4KVDA 5B03A 4NUAA 4JZXA 4XQSF 5ILJA 2J1OA 4LTZA 2F94F 5EROA 1VG3A 1WY0A 2F8CF 4GAXA 3G4FA 3P8RA 3ID0A 5IMNA 5JV0F 4E9UA 5DJVF 4N1ZF 3QKCA 4H5DF 3AQ0A 2Z7HA 3ICZA 4XQTF 4DZWA 3SAEA 3WEGA 5JUZF 4LFGA 5B0MA 4DWBA 3SDQA 3VJAA 4E9ZA 4NFKF 2Q58A 3KRCA 3NPRA 3N0GA 3CC9A 4NKEA 4RXAA 4F6VA 2J5CA 2E94A 2RAHA 1YHLA 5JV1F 1YYRA 4LUUA 1VG4A 3EFQA 1UBXA 5HN7A 1N24A 1V4EA 3M02A 4JVJF 5H9DA 2OGDA 1FPSA 5IKHA 4EA1A 3WCGA 2F8ZF 4L2XF 3LGKA 5DGMF 1UBYA 3WCFA 3KRAA 2E4OA 2AETA 3IBAA 3S9VA 2Z4XA 3DYHA 2ZEVA 2E8WA 1WL1A 3WC9A 3VJEA 1V4IA 3CP6A 4QPFA 3MAVA 4JZBA 3M01A 5DGNF 2I19A 5EATA 3ICKA 2FTZA 3N49F 1YYQA 3N3LF 3PYAA 3P5PA 2E95A 1KIYA 1V4JA 2PS6A 4E1EA 5ILDA 3APZA 4KKMA 3KRAB 2E8UA 2P1CA 4EA0A 3W7FA 2E90A 3N46F 5AHUB 4OMGA 3ICNA 3TC1A 5B02A 1YYUA 2OA6A 4KWDA 2Z52A 1N20A 3UCAA 5ILKA 1N1BA 5ILZA 4KQSA 4NFJF 3PYBA 1VG2A 3LDWA 4LZ0A 3TFPA 3IPIA 5DHKA 2ONHA 3ZL6A 5ER8A 3WEIA 4NKFA 5DHIA 3N45F 5JV2F 1HXGA 5A0KA 3P8LA 2OPNA 2Z4WA 1WKZA 4JXYA 4GA3A 1WMWA 5JA0F 4RYPA 1YHKA 4LA5A 5B0JA 3WJOA 4MC0A 3WEKA 2O1OA 5HNAA 3OACB 5I1UA 1N21A 3WEFA 3ACWA 3N1WF 5EASA 3QQVA 4NG6A 5IMIA 5B0LA 3CKEA 3N5JF 3ZCDA 4LPHF 4P0WA 5AELA 4LZ3A 3LK5A 4KK2A 3SDVA 3WEJA 3VJCA 2F89F 3TFNA 2F9KF 2Z4ZA 4DWGA 5IMPA 2AEKA 2EWGA 5B0KA 1WL3A 2H8OA 4KVIA 5ERMA 3G4DA 3KRFB 2ZCOA 4OGUA 4UMJA 2AZKA 1DI1A 5E8LA 1N23A 4LOBA 3ACXA 3RYEA 5A0JA 3EGTA 4KPDA 4KVYA 2AELA 3V1VA 3Q30A 4LZCA 5A0IA 4RXDA 3TS7A 2ONGA 3WCLA 3AQBB 2Q9YA 4Q23A 1UBWA 4OKMA 2OPMA 5E8KA 2F7MF 5IN8A 3VJBA 4JXNA 3ADZA 5IKAA 2DH4A 5HN9A 2ZEUA 1HX9A 5CG6A 2Z50A 3NRIA 1WL2A 2Z4VA 3ZOUA 3SDUA 5IK0A 4RXCA 1YV5A 5AYPA 4DXJA 2E8VA 3WSBA 3N6KF 5C05A 3N1VF 4LLSA 4K10A 3WCCA 4H5CF 4WK5A 1HXCA 1VG6A 3LZ9A 3LG5A 3DYGA 1YYSA 3LEEA 5EAUA 4RNQA 4EA2A 4F62A 4DI5A 3AQCB 4HD1A 1HXAA 4ZQ8A 4P0VA 1RQIA 4OKZA 4FJQA 4H5EF 3OACA 1PS1A 3ICMA 4LIXA 3WCMA 3RMGA 4KQ5A 4QXSF 1KIZA 3MZVA 5IM1A 1YHMA 1N1ZA 3ZMCA 3ZMBA 4GP1A 4NFIF 5B01A 4LXWA 3EZ3A 2E93A 3TFVA 4KQUA 2Q80A 5E8HA 2AZLA 3LGZB 2E8XA 2FORA 2J1PA 3S4JA 3OYRA 5AFXA 3KRFA 3WCIA 3PDEA 2Q9ZA 3N5HF 3WJNA 3OABB 3WCEA 1V4HA 3AE0A 1HM4A 4MC3A 3WCHA 5KSXF 5ILHA 5DJRF 5B0IA 3V66A 1ZW5A 2ZCQA 3WSAA 2E92A 1RTRA 4DHDA 4LLTA 4KPJA 5ERNA 5DJPF 1WL0A 3WCAA 2PS7A 2Z4YA 3Q1OA 5IL3A
chains in the Genus database with same CATH superfamily
1YQ7A 5CG5A 3WCDA 4KUXA 3KROB 2AZJA 5ILIA 2E8TA 4GP2A 3PKOA 4PVYF 3WE9A 3LVSA 3VJ9A 4DEMF 1EZFA 4FP4A 4MC8A 5IVGA 3NF2A 2QISA 3WEHA 2E91A 3RBMA 2ZY1A 3LMDA 3Q2ZA 1N22A 3KRPA 5B00A 3Q2QA 2Z7IA 3BNYA 2ZCRA 1JFAA 1RQJA 2PS4A 5HN8A 3SDRA 4F6XA 3M0GA 3WCJA 3WJKA 5IK9A 3RYWA 3VJ8A 5DIQF 4LFEA 3V1XA 3KRCB 5IL8A 4KFAA 1YJ4A 2ZCSA 2Z78A 3LSNA 2PS8A 3DYFA 3KB9A 4KVWA 3P5RA 3KRPB 3KBKA 4JYXA 1VG7A 4XQRF 3OABA 5DW7A 3LJIA 5IK6A 4PVXF 3NPKA 3LLWA 1YYTA 3PH7A 3LOMA 3BNXA 3ACYA 4LFVF 2F92F 3ASXA 3VJDA 5DZ2A 4OMHA 5DGSF 4N9UA 1HM7A 4LTVA 5ILYA 3N3DA 3B7LA 1JFGA 3P41A 1V4KA 2PS5A 3KROA 4LA6A 4RXEA 1DGPA 3WCBA 3SDTA 2VF6A 4P0XA 3M00A 3M9UA 1UBVA 4LPGF 3N0FA 4KVDA 5B03A 4NUAA 4JZXA 4XQSF 5ILJA 2J1OA 4LTZA 2F94F 5EROA 1VG3A 1WY0A 2F8CF 4GAXA 3G4FA 3P8RA 3ID0A 5IMNA 5JV0F 4E9UA 5DJVF 4N1ZF 3QKCA 4H5DF 3AQ0A 2Z7HA 3ICZA 4XQTF 4DZWA 3SAEA 3WEGA 5JUZF 4LFGA 5B0MA 4DWBA 3SDQA 3VJAA 4E9ZA 4NFKF 2Q58A 3KRCA 3NPRA 3N0GA 3CC9A 4NKEA 4RXAA 4F6VA 2J5CA 2E94A 2RAHA 1YHLA 5JV1F 1YYRA 4LUUA 1VG4A 3EFQA 1UBXA 5HN7A 1N24A 1V4EA 3M02A 4JVJF 5H9DA 2OGDA 1FPSA 5IKHA 4EA1A 3WCGA 2F8ZF 4L2XF 3LGKA 5DGMF 1UBYA 3WCFA 3KRAA 2E4OA 2AETA 3IBAA 3S9VA 2Z4XA 3DYHA 2ZEVA 2E8WA 1WL1A 3WC9A 3VJEA 1V4IA 3CP6A 4QPFA 3MAVA 4JZBA 3M01A 5DGNF 2I19A 5EATA 3ICKA 2FTZA 3N49F 1YYQA 3N3LF 3PYAA 3P5PA 2E95A 1KIYA 1V4JA 2PS6A 4E1EA 5ILDA 3APZA 4KKMA 3KRAB 2E8UA 2P1CA 4EA0A 3W7FA 2E90A 3N46F 5AHUB 4OMGA 3ICNA 3TC1A 5B02A 1YYUA 2OA6A 4KWDA 2Z52A 1N20A 3UCAA 5ILKA 1N1BA 5ILZA 4KQSA 4NFJF 3PYBA 1VG2A 3LDWA 4LZ0A 3TFPA 3IPIA 5DHKA 2ONHA 3ZL6A 5ER8A 3WEIA 4NKFA 5DHIA 3N45F 5JV2F 1HXGA 5A0KA 3P8LA 2OPNA 2Z4WA 1WKZA 4JXYA 4GA3A 1WMWA 5JA0F 4RYPA 1YHKA 4LA5A 5B0JA 3WJOA 4MC0A 3WEKA 2O1OA 5HNAA 3OACB 5I1UA 1N21A 3WEFA 3ACWA 3N1WF 5EASA 3QQVA 4NG6A 5IMIA 5B0LA 3CKEA 3N5JF 3ZCDA 4LPHF 4P0WA 5AELA 4LZ3A 3LK5A 4KK2A 3SDVA 3WEJA 3VJCA 2F89F 3TFNA 2F9KF 2Z4ZA 4DWGA 5IMPA 2AEKA 2EWGA 5B0KA 1WL3A 2H8OA 4KVIA 5ERMA 3G4DA 3KRFB 2ZCOA 4OGUA 4UMJA 2AZKA 1DI1A 5E8LA 1N23A 4LOBA 3ACXA 3RYEA 5A0JA 3EGTA 4KPDA 4KVYA 2AELA 3V1VA 3Q30A 4LZCA 5A0IA 4RXDA 3TS7A 2ONGA 3WCLA 3AQBB 2Q9YA 4Q23A 1UBWA 4OKMA 2OPMA 5E8KA 2F7MF 5IN8A 3VJBA 4JXNA 3ADZA 5IKAA 2DH4A 5HN9A 2ZEUA 1HX9A 5CG6A 2Z50A 3NRIA 1WL2A 2Z4VA 3ZOUA 3SDUA 5IK0A 4RXCA 1YV5A 5AYPA 4DXJA 2E8VA 3WSBA 3N6KF 5C05A 3N1VF 4LLSA 4K10A 3WCCA 4H5CF 4WK5A 1HXCA 1VG6A 3LZ9A 3LG5A 3DYGA 1YYSA 3LEEA 5EAUA 4RNQA 4EA2A 4F62A 4DI5A 3AQCB 4HD1A 1HXAA 4ZQ8A 4P0VA 1RQIA 4OKZA 4FJQA 4H5EF 3OACA 1PS1A 3ICMA 4LIXA 3WCMA 3RMGA 4KQ5A 4QXSF 1KIZA 3MZVA 5IM1A 1YHMA 1N1ZA 3ZMCA 3ZMBA 4GP1A 4NFIF 5B01A 4LXWA 3EZ3A 2E93A 3TFVA 4KQUA 2Q80A 5E8HA 2AZLA 3LGZB 2E8XA 2FORA 2J1PA 3S4JA 3OYRA 5AFXA 3KRFA 3WCIA 3PDEA 2Q9ZA 3N5HF 3WJNA 3OABB 3WCEA 1V4HA 3AE0A 1HM4A 4MC3A 3WCHA 5KSXF 5ILHA 5DJRF 5B0IA 3V66A 1ZW5A 2ZCQA 3WSAA 2E92A 1RTRA 4DHDA 4LLTA 4KPJA 5ERNA 5DJPF 1WL0A 3WCAA 2PS7A 2Z4YA 3Q1OA 5IL3A
chains in the Genus database with same CATH topology
1YQ7A 5CG5A 3WCDA 4KUXA 3KROB 2AZJA 5ILIA 2E8TA 4GP2A 3PKOA 4PVYF 3WE9A 3LVSA 3VJ9A 4DEMF 1EZFA 4FP4A 4MC8A 5IVGA 3NF2A 2QISA 3WEHA 2E91A 3RBMA 2ZY1A 3LMDA 3Q2ZA 1N22A 3KRPA 5B00A 3Q2QA 2Z7IA 3BNYA 2ZCRA 1JFAA 1RQJA 2PS4A 5HN8A 3SDRA 4F6XA 3M0GA 3WCJA 3WJKA 5IK9A 3RYWA 3VJ8A 5DIQF 4LFEA 3V1XA 3KRCB 5IL8A 4KFAA 1YJ4A 2ZCSA 2Z78A 3LSNA 2PS8A 3DYFA 3KB9A 4KVWA 3P5RA 3KRPB 3KBKA 4JYXA 1VG7A 4XQRF 3OABA 5DW7A 3LJIA 5IK6A 4PVXF 3NPKA 3LLWA 1YYTA 3PH7A 3LOMA 3BNXA 3ACYA 4LFVF 2F92F 3ASXA 3VJDA 5DZ2A 4OMHA 5DGSF 4N9UA 1HM7A 4LTVA 5ILYA 3N3DA 3B7LA 1JFGA 3P41A 1V4KA 2PS5A 3KROA 4LA6A 4RXEA 1DGPA 3WCBA 3SDTA 2VF6A 4P0XA 3M00A 3M9UA 1UBVA 4LPGF 3N0FA 4KVDA 5B03A 4NUAA 4JZXA 4XQSF 5ILJA 2J1OA 4LTZA 2F94F 5EROA 1VG3A 1WY0A 2F8CF 4GAXA 3G4FA 3P8RA 3ID0A 5IMNA 5JV0F 4E9UA 5DJVF 4N1ZF 3QKCA 4H5DF 3AQ0A 2Z7HA 3ICZA 4XQTF 4DZWA 3SAEA 3WEGA 5JUZF 4LFGA 5B0MA 4DWBA 3SDQA 3VJAA 4E9ZA 4NFKF 2Q58A 3KRCA 3NPRA 3N0GA 3CC9A 4NKEA 4RXAA 4F6VA 2J5CA 2E94A 2RAHA 1YHLA 5JV1F 1YYRA 4LUUA 1VG4A 3EFQA 1UBXA 5HN7A 1N24A 1V4EA 3M02A 4JVJF 5H9DA 2OGDA 1FPSA 5IKHA 4EA1A 3WCGA 2F8ZF 4L2XF 3LGKA 5DGMF 1UBYA 3WCFA 3KRAA 2E4OA 2AETA 3IBAA 3S9VA 2Z4XA 3DYHA 2ZEVA 2E8WA 1WL1A 3WC9A 3VJEA 1V4IA 3CP6A 4QPFA 3MAVA 4JZBA 3M01A 5DGNF 2I19A 5EATA 3ICKA 2FTZA 3N49F 1YYQA 3N3LF 3PYAA 3P5PA 2E95A 1KIYA 1V4JA 2PS6A 4E1EA 5ILDA 3APZA 4KKMA 3KRAB 2E8UA 2P1CA 4EA0A 3W7FA 2E90A 3N46F 5AHUB 4OMGA 3ICNA 3TC1A 5B02A 1YYUA 2OA6A 4KWDA 2Z52A 1N20A 3UCAA 5ILKA 1N1BA 5ILZA 4KQSA 4NFJF 3PYBA 1VG2A 3LDWA 4LZ0A 3TFPA 3IPIA 5DHKA 2ONHA 3ZL6A 5ER8A 3WEIA 4NKFA 5DHIA 3N45F 5JV2F 1HXGA 5A0KA 3P8LA 2OPNA 2Z4WA 1WKZA 4JXYA 4GA3A 1WMWA 5JA0F 4RYPA 1YHKA 4LA5A 5B0JA 3WJOA 4MC0A 3WEKA 2O1OA 5HNAA 3OACB 5I1UA 1N21A 3WEFA 3ACWA 3N1WF 5EASA 3QQVA 4NG6A 5IMIA 5B0LA 3CKEA 3N5JF 3ZCDA 4LPHF 4P0WA 5AELA 4LZ3A 3LK5A 4KK2A 3SDVA 3WEJA 3VJCA 2F89F 3TFNA 2F9KF 2Z4ZA 4DWGA 5IMPA 2AEKA 2EWGA 5B0KA 1WL3A 2H8OA 4KVIA 5ERMA 3G4DA 3KRFB 2ZCOA 4OGUA 4UMJA 2AZKA 1DI1A 5E8LA 1N23A 4LOBA 3ACXA 3RYEA 5A0JA 3EGTA 4KPDA 4KVYA 2AELA 3V1VA 3Q30A 4LZCA 5A0IA 4RXDA 3TS7A 2ONGA 3WCLA 3AQBB 2Q9YA 4Q23A 1UBWA 4OKMA 2OPMA 5E8KA 2F7MF 5IN8A 3VJBA 4JXNA 3ADZA 5IKAA 2DH4A 5HN9A 2ZEUA 1HX9A 5CG6A 2Z50A 3NRIA 1WL2A 2Z4VA 3ZOUA 3SDUA 5IK0A 4RXCA 1YV5A 5AYPA 4DXJA 2E8VA 3WSBA 3N6KF 5C05A 3N1VF 4LLSA 4K10A 3WCCA 4H5CF 4WK5A 1HXCA 1VG6A 3LZ9A 3LG5A 3DYGA 1YYSA 3LEEA 5EAUA 4RNQA 4EA2A 4F62A 4DI5A 3AQCB 4HD1A 1HXAA 4ZQ8A 4P0VA 1RQIA 4OKZA 4FJQA 4H5EF 3OACA 1PS1A 3ICMA 4LIXA 3WCMA 3RMGA 4KQ5A 4QXSF 1KIZA 3MZVA 5IM1A 1YHMA 1N1ZA 3ZMCA 3ZMBA 4GP1A 4NFIF 5B01A 4LXWA 3EZ3A 2E93A 3TFVA 4KQUA 2Q80A 5E8HA 2AZLA 3LGZB 2E8XA 2FORA 2J1PA 3S4JA 3OYRA 5AFXA 3KRFA 3WCIA 3PDEA 2Q9ZA 3N5HF 3WJNA 3OABB 3WCEA 1V4HA 3AE0A 1HM4A 4MC3A 3WCHA 5KSXF 5ILHA 5DJRF 5B0IA 3V66A 1ZW5A 2ZCQA 3WSAA 2E92A 1RTRA 4DHDA 4LLTA 4KPJA 5ERNA 5DJPF 1WL0A 3WCAA 2PS7A 2Z4YA 3Q1OA 5IL3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YQ7 A;  5CG5 A;  3WCD A;  4KUX A;  3KRO B;  2AZJ A;  5ILI A;  2E8T A;  4GP2 A;  3PKO A;  4PVY F;  3WE9 A;  3LVS A;  3VJ9 A;  4DEM F;  1EZF A;  4FP4 A;  4MC8 A;  5IVG A;  3NF2 A;  2QIS A;  3WEH A;  2E91 A;  3RBM A;  2ZY1 A;  3LMD A;  3Q2Z A;  1N22 A;  3KRP A;  5B00 A;  3Q2Q A;  2Z7I A;  3BNY A;  2ZCR A;  1JFA A;  1RQJ A;  2PS4 A;  5HN8 A;  3SDR A;  4F6X A;  3M0G A;  3WCJ A;  3WJK A;  5IK9 A;  3RYW A;  3VJ8 A;  5DIQ F;  4LFE A;  3V1X A;  3KRC B;  5IL8 A;  4KFA A;  1YJ4 A;  2ZCS A;  2Z78 A;  3LSN A;  2PS8 A;  3DYF A;  3KB9 A;  4KVW A;  3P5R A;  3KRP B;  3KBK A;  4JYX A;  1VG7 A;  4XQR F;  3OAB A;  5DW7 A;  3LJI A;  5IK6 A;  4PVX F;  3NPK A;  3LLW A;  1YYT A;  3PH7 A;  3LOM A;  3BNX A;  3ACY A;  4LFV F;  2F92 F;  3ASX A;  3VJD A;  5DZ2 A;  4OMH A;  5DGS F;  4N9U A;  1HM7 A;  4LTV A;  5ILY A;  3N3D A;  3B7L A;  1JFG A;  3P41 A;  1V4K A;  2PS5 A;  3KRO A;  4LA6 A;  4RXE A;  1DGP A;  3WCB A;  3SDT A;  2VF6 A;  4P0X A;  3M00 A;  3M9U A;  1UBV A;  4LPG F;  3N0F A;  4KVD A;  5B03 A;  4NUA A;  4JZX A;  4XQS F;  5ILJ A;  2J1O A;  4LTZ A;  2F94 F;  5ERO A;  1VG3 A;  1WY0 A;  2F8C F;  4GAX A;  3G4F A;  3P8R A;  3ID0 A;  5IMN A;  5JV0 F;  4E9U A;  5DJV F;  4N1Z F;  3QKC A;  4H5D F;  3AQ0 A;  2Z7H A;  3ICZ A;  4XQT F;  4DZW A;  3SAE A;  3WEG A;  5JUZ F;  4LFG A;  5B0M A;  4DWB A;  3SDQ A;  3VJA A;  4E9Z A;  4NFK F;  2Q58 A;  3KRC A;  3NPR A;  3N0G A;  3CC9 A;  4NKE A;  4RXA A;  4F6V A;  2J5C A;  2E94 A;  2RAH A;  1YHL A;  5JV1 F;  1YYR A;  4LUU A;  1VG4 A;  3EFQ A;  1UBX A;  5HN7 A;  1N24 A;  1V4E A;  3M02 A;  4JVJ F;  5H9D A;  2OGD A;  1FPS A;  5IKH A;  4EA1 A;  3WCG A;  2F8Z F;  4L2X F;  3LGK A;  5DGM F;  1UBY A;  3WCF A;  3KRA A;  2E4O A;  2AET A;  3IBA A;  3S9V A;  2Z4X A;  3DYH A;  2ZEV A;  2E8W A;  1WL1 A;  3WC9 A;  3VJE A;  1V4I A;  3CP6 A;  4QPF A;  3MAV A;  4JZB A;  3M01 A;  5DGN F;  2I19 A;  5EAT A;  3ICK A;  2FTZ A;  3N49 F;  1YYQ A;  3N3L F;  3PYA A;  3P5P A;  2E95 A;  1KIY A;  1V4J A;  2PS6 A;  4E1E A;  5ILD A;  3APZ A;  4KKM A;  3KRA B;  2E8U A;  2P1C A;  4EA0 A;  3W7F A;  2E90 A;  3N46 F;  5AHU B;  4OMG A;  3ICN A;  3TC1 A;  5B02 A;  1YYU A;  2OA6 A;  4KWD A;  2Z52 A;  1N20 A;  3UCA A;  5ILK A;  1N1B A;  5ILZ A;  4KQS A;  4NFJ F;  3PYB A;  1VG2 A;  3LDW A;  4LZ0 A;  3TFP A;  3IPI A;  5DHK A;  2ONH A;  3ZL6 A;  5ER8 A;  3WEI A;  4NKF A;  5DHI A;  3N45 F;  5JV2 F;  1HXG A;  5A0K A;  3P8L A;  2OPN A;  2Z4W A;  1WKZ A;  4JXY A;  4GA3 A;  1WMW A;  5JA0 F;  4RYP A;  1YHK A;  4LA5 A;  5B0J A;  3WJO A;  4MC0 A;  3WEK A;  2O1O A;  5HNA A;  3OAC B;  5I1U A;  1N21 A;  3WEF A;  3ACW A;  3N1W F;  5EAS A;  3QQV A;  4NG6 A;  5IMI A;  5B0L A;  3CKE A;  3N5J F;  3ZCD A;  4LPH F;  4P0W A;  5AEL A;  4LZ3 A;  3LK5 A;  4KK2 A;  3SDV A;  3WEJ A;  3VJC A;  2F89 F;  3TFN A;  2F9K F;  2Z4Z A;  4DWG A;  5IMP A;  2AEK A;  2EWG A;  5B0K A;  1WL3 A;  2H8O A;  4KVI A;  5ERM A;  3G4D A;  3KRF B;  2ZCO A;  4OGU A;  4UMJ A;  2AZK A;  1DI1 A;  5E8L A;  1N23 A;  4LOB A;  3ACX A;  3RYE A;  5A0J A;  3EGT A;  4KPD A;  4KVY A;  2AEL A;  3V1V A;  3Q30 A;  4LZC A;  5A0I A;  4RXD A;  3TS7 A;  2ONG A;  3WCL A;  3AQB B;  2Q9Y A;  4Q23 A;  1UBW A;  4OKM A;  2OPM A;  5E8K A;  2F7M F;  5IN8 A;  3VJB A;  4JXN A;  3ADZ A;  5IKA A;  2DH4 A;  5HN9 A;  2ZEU A;  1HX9 A;  5CG6 A;  2Z50 A;  3NRI A;  1WL2 A;  2Z4V A;  3ZOU A;  3SDU A;  5IK0 A;  4RXC A;  1YV5 A;  5AYP A;  4DXJ A;  2E8V A;  3WSB A;  3N6K F;  5C05 A;  3N1V F;  4LLS A;  4K10 A;  3WCC A;  4H5C F;  4WK5 A;  1HXC A;  1VG6 A;  3LZ9 A;  3LG5 A;  3DYG A;  1YYS A;  3LEE A;  5EAU A;  4RNQ A;  4EA2 A;  4F62 A;  4DI5 A;  3AQC B;  4HD1 A;  1HXA A;  4ZQ8 A;  4P0V A;  1RQI A;  4OKZ A;  4FJQ A;  4H5E F;  3OAC A;  1PS1 A;  3ICM A;  4LIX A;  3WCM A;  3RMG A;  4KQ5 A;  4QXS F;  1KIZ A;  3MZV A;  5IM1 A;  1YHM A;  1N1Z A;  3ZMC A;  3ZMB A;  4GP1 A;  4NFI F;  5B01 A;  4LXW A;  3EZ3 A;  2E93 A;  3TFV A;  4KQU A;  2Q80 A;  5E8H A;  2AZL A;  3LGZ B;  2E8X A;  2FOR A;  2J1P A;  3S4J A;  3OYR A;  5AFX A;  3KRF A;  3WCI A;  3PDE A;  2Q9Z A;  3N5H F;  3WJN A;  3OAB B;  3WCE A;  1V4H A;  3AE0 A;  1HM4 A;  4MC3 A;  3WCH A;  5KSX F;  5ILH A;  5DJR F;  5B0I A;  3V66 A;  1ZW5 A;  2ZCQ A;  3WSA A;  2E92 A;  1RTR A;  4DHD A;  4LLT A;  4KPJ A;  5ERN A;  5DJP F;  1WL0 A;  3WCA A;  2PS7 A;  2Z4Y A;  3Q1O A;  5IL3 A; 
#chains in the Genus database with same CATH topology
 1YQ7 A;  5CG5 A;  3WCD A;  4KUX A;  3KRO B;  2AZJ A;  5ILI A;  2E8T A;  4GP2 A;  3PKO A;  4PVY F;  3WE9 A;  3LVS A;  3VJ9 A;  4DEM F;  1EZF A;  4FP4 A;  4MC8 A;  5IVG A;  3NF2 A;  2QIS A;  3WEH A;  2E91 A;  3RBM A;  2ZY1 A;  3LMD A;  3Q2Z A;  1N22 A;  3KRP A;  5B00 A;  3Q2Q A;  2Z7I A;  3BNY A;  2ZCR A;  1JFA A;  1RQJ A;  2PS4 A;  5HN8 A;  3SDR A;  4F6X A;  3M0G A;  3WCJ A;  3WJK A;  5IK9 A;  3RYW A;  3VJ8 A;  5DIQ F;  4LFE A;  3V1X A;  3KRC B;  5IL8 A;  4KFA A;  1YJ4 A;  2ZCS A;  2Z78 A;  3LSN A;  2PS8 A;  3DYF A;  3KB9 A;  4KVW A;  3P5R A;  3KRP B;  3KBK A;  4JYX A;  1VG7 A;  4XQR F;  3OAB A;  5DW7 A;  3LJI A;  5IK6 A;  4PVX F;  3NPK A;  3LLW A;  1YYT A;  3PH7 A;  3LOM A;  3BNX A;  3ACY A;  4LFV F;  2F92 F;  3ASX A;  3VJD A;  5DZ2 A;  4OMH A;  5DGS F;  4N9U A;  1HM7 A;  4LTV A;  5ILY A;  3N3D A;  3B7L A;  1JFG A;  3P41 A;  1V4K A;  2PS5 A;  3KRO A;  4LA6 A;  4RXE A;  1DGP A;  3WCB A;  3SDT A;  2VF6 A;  4P0X A;  3M00 A;  3M9U A;  1UBV A;  4LPG F;  3N0F A;  4KVD A;  5B03 A;  4NUA A;  4JZX A;  4XQS F;  5ILJ A;  2J1O A;  4LTZ A;  2F94 F;  5ERO A;  1VG3 A;  1WY0 A;  2F8C F;  4GAX A;  3G4F A;  3P8R A;  3ID0 A;  5IMN A;  5JV0 F;  4E9U A;  5DJV F;  4N1Z F;  3QKC A;  4H5D F;  3AQ0 A;  2Z7H A;  3ICZ A;  4XQT F;  4DZW A;  3SAE A;  3WEG A;  5JUZ F;  4LFG A;  5B0M A;  4DWB A;  3SDQ A;  3VJA A;  4E9Z A;  4NFK F;  2Q58 A;  3KRC A;  3NPR A;  3N0G A;  3CC9 A;  4NKE A;  4RXA A;  4F6V A;  2J5C A;  2E94 A;  2RAH A;  1YHL A;  5JV1 F;  1YYR A;  4LUU A;  1VG4 A;  3EFQ A;  1UBX A;  5HN7 A;  1N24 A;  1V4E A;  3M02 A;  4JVJ F;  5H9D A;  2OGD A;  1FPS A;  5IKH A;  4EA1 A;  3WCG A;  2F8Z F;  4L2X F;  3LGK A;  5DGM F;  1UBY A;  3WCF A;  3KRA A;  2E4O A;  2AET A;  3IBA A;  3S9V A;  2Z4X A;  3DYH A;  2ZEV A;  2E8W A;  1WL1 A;  3WC9 A;  3VJE A;  1V4I A;  3CP6 A;  4QPF A;  3MAV A;  4JZB A;  3M01 A;  5DGN F;  2I19 A;  5EAT A;  3ICK A;  2FTZ A;  3N49 F;  1YYQ A;  3N3L F;  3PYA A;  3P5P A;  2E95 A;  1KIY A;  1V4J A;  2PS6 A;  4E1E A;  5ILD A;  3APZ A;  4KKM A;  3KRA B;  2E8U A;  2P1C A;  4EA0 A;  3W7F A;  2E90 A;  3N46 F;  5AHU B;  4OMG A;  3ICN A;  3TC1 A;  5B02 A;  1YYU A;  2OA6 A;  4KWD A;  2Z52 A;  1N20 A;  3UCA A;  5ILK A;  1N1B A;  5ILZ A;  4KQS A;  4NFJ F;  3PYB A;  1VG2 A;  3LDW A;  4LZ0 A;  3TFP A;  3IPI A;  5DHK A;  2ONH A;  3ZL6 A;  5ER8 A;  3WEI A;  4NKF A;  5DHI A;  3N45 F;  5JV2 F;  1HXG A;  5A0K A;  3P8L A;  2OPN A;  2Z4W A;  1WKZ A;  4JXY A;  4GA3 A;  1WMW A;  5JA0 F;  4RYP A;  1YHK A;  4LA5 A;  5B0J A;  3WJO A;  4MC0 A;  3WEK A;  2O1O A;  5HNA A;  3OAC B;  5I1U A;  1N21 A;  3WEF A;  3ACW A;  3N1W F;  5EAS A;  3QQV A;  4NG6 A;  5IMI A;  5B0L A;  3CKE A;  3N5J F;  3ZCD A;  4LPH F;  4P0W A;  5AEL A;  4LZ3 A;  3LK5 A;  4KK2 A;  3SDV A;  3WEJ A;  3VJC A;  2F89 F;  3TFN A;  2F9K F;  2Z4Z A;  4DWG A;  5IMP A;  2AEK A;  2EWG A;  5B0K A;  1WL3 A;  2H8O A;  4KVI A;  5ERM A;  3G4D A;  3KRF B;  2ZCO A;  4OGU A;  4UMJ A;  2AZK A;  1DI1 A;  5E8L A;  1N23 A;  4LOB A;  3ACX A;  3RYE A;  5A0J A;  3EGT A;  4KPD A;  4KVY A;  2AEL A;  3V1V A;  3Q30 A;  4LZC A;  5A0I A;  4RXD A;  3TS7 A;  2ONG A;  3WCL A;  3AQB B;  2Q9Y A;  4Q23 A;  1UBW A;  4OKM A;  2OPM A;  5E8K A;  2F7M F;  5IN8 A;  3VJB A;  4JXN A;  3ADZ A;  5IKA A;  2DH4 A;  5HN9 A;  2ZEU A;  1HX9 A;  5CG6 A;  2Z50 A;  3NRI A;  1WL2 A;  2Z4V A;  3ZOU A;  3SDU A;  5IK0 A;  4RXC A;  1YV5 A;  5AYP A;  4DXJ A;  2E8V A;  3WSB A;  3N6K F;  5C05 A;  3N1V F;  4LLS A;  4K10 A;  3WCC A;  4H5C F;  4WK5 A;  1HXC A;  1VG6 A;  3LZ9 A;  3LG5 A;  3DYG A;  1YYS A;  3LEE A;  5EAU A;  4RNQ A;  4EA2 A;  4F62 A;  4DI5 A;  3AQC B;  4HD1 A;  1HXA A;  4ZQ8 A;  4P0V A;  1RQI A;  4OKZ A;  4FJQ A;  4H5E F;  3OAC A;  1PS1 A;  3ICM A;  4LIX A;  3WCM A;  3RMG A;  4KQ5 A;  4QXS F;  1KIZ A;  3MZV A;  5IM1 A;  1YHM A;  1N1Z A;  3ZMC A;  3ZMB A;  4GP1 A;  4NFI F;  5B01 A;  4LXW A;  3EZ3 A;  2E93 A;  3TFV A;  4KQU A;  2Q80 A;  5E8H A;  2AZL A;  3LGZ B;  2E8X A;  2FOR A;  2J1P A;  3S4J A;  3OYR A;  5AFX A;  3KRF A;  3WCI A;  3PDE A;  2Q9Z A;  3N5H F;  3WJN A;  3OAB B;  3WCE A;  1V4H A;  3AE0 A;  1HM4 A;  4MC3 A;  3WCH A;  5KSX F;  5ILH A;  5DJR F;  5B0I A;  3V66 A;  1ZW5 A;  2ZCQ A;  3WSA A;  2E92 A;  1RTR A;  4DHD A;  4LLT A;  4KPJ A;  5ERN A;  5DJP F;  1WL0 A;  3WCA A;  2PS7 A;  2Z4Y A;  3Q1O A;  5IL3 A; 
#chains in the Genus database with same CATH homology
 1YQ7 A;  5CG5 A;  3WCD A;  4KUX A;  3KRO B;  2AZJ A;  5ILI A;  2E8T A;  4GP2 A;  3PKO A;  4PVY F;  3WE9 A;  3LVS A;  3VJ9 A;  4DEM F;  1EZF A;  4FP4 A;  4MC8 A;  5IVG A;  3NF2 A;  2QIS A;  3WEH A;  2E91 A;  3RBM A;  2ZY1 A;  3LMD A;  3Q2Z A;  1N22 A;  3KRP A;  5B00 A;  3Q2Q A;  2Z7I A;  3BNY A;  2ZCR A;  1JFA A;  1RQJ A;  2PS4 A;  5HN8 A;  3SDR A;  4F6X A;  3M0G A;  3WCJ A;  3WJK A;  5IK9 A;  3RYW A;  3VJ8 A;  5DIQ F;  4LFE A;  3V1X A;  3KRC B;  5IL8 A;  4KFA A;  1YJ4 A;  2ZCS A;  2Z78 A;  3LSN A;  2PS8 A;  3DYF A;  3KB9 A;  4KVW A;  3P5R A;  3KRP B;  3KBK A;  4JYX A;  1VG7 A;  4XQR F;  3OAB A;  5DW7 A;  3LJI A;  5IK6 A;  4PVX F;  3NPK A;  3LLW A;  1YYT A;  3PH7 A;  3LOM A;  3BNX A;  3ACY A;  4LFV F;  2F92 F;  3ASX A;  3VJD A;  5DZ2 A;  4OMH A;  5DGS F;  4N9U A;  1HM7 A;  4LTV A;  5ILY A;  3N3D A;  3B7L A;  1JFG A;  3P41 A;  1V4K A;  2PS5 A;  3KRO A;  4LA6 A;  4RXE A;  1DGP A;  3WCB A;  3SDT A;  2VF6 A;  4P0X A;  3M00 A;  3M9U A;  1UBV A;  4LPG F;  3N0F A;  4KVD A;  5B03 A;  4NUA A;  4JZX A;  4XQS F;  5ILJ A;  2J1O A;  4LTZ A;  2F94 F;  5ERO A;  1VG3 A;  1WY0 A;  2F8C F;  4GAX A;  3G4F A;  3P8R A;  3ID0 A;  5IMN A;  5JV0 F;  4E9U A;  5DJV F;  4N1Z F;  3QKC A;  4H5D F;  3AQ0 A;  2Z7H A;  3ICZ A;  4XQT F;  4DZW A;  3SAE A;  3WEG A;  5JUZ F;  4LFG A;  5B0M A;  4DWB A;  3SDQ A;  3VJA A;  4E9Z A;  4NFK F;  2Q58 A;  3KRC A;  3NPR A;  3N0G A;  3CC9 A;  4NKE A;  4RXA A;  4F6V A;  2J5C A;  2E94 A;  2RAH A;  1YHL A;  5JV1 F;  1YYR A;  4LUU A;  1VG4 A;  3EFQ A;  1UBX A;  5HN7 A;  1N24 A;  1V4E A;  3M02 A;  4JVJ F;  5H9D A;  2OGD A;  1FPS A;  5IKH A;  4EA1 A;  3WCG A;  2F8Z F;  4L2X F;  3LGK A;  5DGM F;  1UBY A;  3WCF A;  3KRA A;  2E4O A;  2AET A;  3IBA A;  3S9V A;  2Z4X A;  3DYH A;  2ZEV A;  2E8W A;  1WL1 A;  3WC9 A;  3VJE A;  1V4I A;  3CP6 A;  4QPF A;  3MAV A;  4JZB A;  3M01 A;  5DGN F;  2I19 A;  5EAT A;  3ICK A;  2FTZ A;  3N49 F;  1YYQ A;  3N3L F;  3PYA A;  3P5P A;  2E95 A;  1KIY A;  1V4J A;  2PS6 A;  4E1E A;  5ILD A;  3APZ A;  4KKM A;  3KRA B;  2E8U A;  2P1C A;  4EA0 A;  3W7F A;  2E90 A;  3N46 F;  5AHU B;  4OMG A;  3ICN A;  3TC1 A;  5B02 A;  1YYU A;  2OA6 A;  4KWD A;  2Z52 A;  1N20 A;  3UCA A;  5ILK A;  1N1B A;  5ILZ A;  4KQS A;  4NFJ F;  3PYB A;  1VG2 A;  3LDW A;  4LZ0 A;  3TFP A;  3IPI A;  5DHK A;  2ONH A;  3ZL6 A;  5ER8 A;  3WEI A;  4NKF A;  5DHI A;  3N45 F;  5JV2 F;  1HXG A;  5A0K A;  3P8L A;  2OPN A;  2Z4W A;  1WKZ A;  4JXY A;  4GA3 A;  1WMW A;  5JA0 F;  4RYP A;  1YHK A;  4LA5 A;  5B0J A;  3WJO A;  4MC0 A;  3WEK A;  2O1O A;  5HNA A;  3OAC B;  5I1U A;  1N21 A;  3WEF A;  3ACW A;  3N1W F;  5EAS A;  3QQV A;  4NG6 A;  5IMI A;  5B0L A;  3CKE A;  3N5J F;  3ZCD A;  4LPH F;  4P0W A;  5AEL A;  4LZ3 A;  3LK5 A;  4KK2 A;  3SDV A;  3WEJ A;  3VJC A;  2F89 F;  3TFN A;  2F9K F;  2Z4Z A;  4DWG A;  5IMP A;  2AEK A;  2EWG A;  5B0K A;  1WL3 A;  2H8O A;  4KVI A;  5ERM A;  3G4D A;  3KRF B;  2ZCO A;  4OGU A;  4UMJ A;  2AZK A;  1DI1 A;  5E8L A;  1N23 A;  4LOB A;  3ACX A;  3RYE A;  5A0J A;  3EGT A;  4KPD A;  4KVY A;  2AEL A;  3V1V A;  3Q30 A;  4LZC A;  5A0I A;  4RXD A;  3TS7 A;  2ONG A;  3WCL A;  3AQB B;  2Q9Y A;  4Q23 A;  1UBW A;  4OKM A;  2OPM A;  5E8K A;  2F7M F;  5IN8 A;  3VJB A;  4JXN A;  3ADZ A;  5IKA A;  2DH4 A;  5HN9 A;  2ZEU A;  1HX9 A;  5CG6 A;  2Z50 A;  3NRI A;  1WL2 A;  2Z4V A;  3ZOU A;  3SDU A;  5IK0 A;  4RXC A;  1YV5 A;  5AYP A;  4DXJ A;  2E8V A;  3WSB A;  3N6K F;  5C05 A;  3N1V F;  4LLS A;  4K10 A;  3WCC A;  4H5C F;  4WK5 A;  1HXC A;  1VG6 A;  3LZ9 A;  3LG5 A;  3DYG A;  1YYS A;  3LEE A;  5EAU A;  4RNQ A;  4EA2 A;  4F62 A;  4DI5 A;  3AQC B;  4HD1 A;  1HXA A;  4ZQ8 A;  4P0V A;  1RQI A;  4OKZ A;  4FJQ A;  4H5E F;  3OAC A;  1PS1 A;  3ICM A;  4LIX A;  3WCM A;  3RMG A;  4KQ5 A;  4QXS F;  1KIZ A;  3MZV A;  5IM1 A;  1YHM A;  1N1Z A;  3ZMC A;  3ZMB A;  4GP1 A;  4NFI F;  5B01 A;  4LXW A;  3EZ3 A;  2E93 A;  3TFV A;  4KQU A;  2Q80 A;  5E8H A;  2AZL A;  3LGZ B;  2E8X A;  2FOR A;  2J1P A;  3S4J A;  3OYR A;  5AFX A;  3KRF A;  3WCI A;  3PDE A;  2Q9Z A;  3N5H F;  3WJN A;  3OAB B;  3WCE A;  1V4H A;  3AE0 A;  1HM4 A;  4MC3 A;  3WCH A;  5KSX F;  5ILH A;  5DJR F;  5B0I A;  3V66 A;  1ZW5 A;  2ZCQ A;  3WSA A;  2E92 A;  1RTR A;  4DHD A;  4LLT A;  4KPJ A;  5ERN A;  5DJP F;  1WL0 A;  3WCA A;  2PS7 A;  2Z4Y A;  3Q1O A;  5IL3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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